Page last updated: 2024-10-22

aristolochic acid i and Carcinoma, Transitional Cell

aristolochic acid i has been researched along with Carcinoma, Transitional Cell in 28 studies

aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.

Carcinoma, Transitional Cell: A malignant neoplasm derived from TRANSITIONAL EPITHELIAL CELLS, occurring chiefly in the URINARY BLADDER; URETERS; or RENAL PELVIS.

Research Excerpts

ExcerptRelevanceReference
"Balkan endemic nephropathy is a chronic tubulointerstitial disease with insidious onset, slowly progressing to end-stage renal disease and frequently associated with urothelial carcinoma of the upper urinary tract (UTUC)."2.61Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid. ( Arlt, VM; Colet, JM; Dika, Ž; Jelaković, B; Nikolić, J; Nortier, JL; Pavlović, NM; Stiborova, M; Vanherweghem, JL, 2019)
"UTUC and bladder cancer share some common risk factors, even if they are two different entities regarding practical, biological and clinical characteristics."2.55Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC). ( Babjuk, M; Chade, DC; Fernández, MI; Fritsche, HM; Grollman, AP; Kassouf, W; Kikuchi, E; Lerner, SP; Lotan, Y; Rink, M; Shariat, SF; Soria, F; Spiess, PE; Thalmann, GN; Ye, D, 2017)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.14)18.2507
2000's8 (28.57)29.6817
2010's10 (35.71)24.3611
2020's8 (28.57)2.80

Authors

AuthorsStudies
Karanović, S1
Ardin, M1
Tang, Z1
Tomić, K1
Villar, S1
Renard, C1
Venturini, E1
Lorch, AH1
Lee, DS1
Stipančić, Ž1
Slade, N2
Vuković Brinar, I1
Dittrich, D1
Karlović, K1
Borovečki, F1
Dickman, KG4
Olivier, M1
Grollman, AP6
Jelaković, B3
Zavadil, J2
Thangavelu, M1
Ismail, A1
Zakaria, A1
Elmansy, H1
Shahrour, W1
Prowse, O1
Kotb, A1
Chen, CH4
Pu, YS4
Li, S1
Zhang, J2
Tian, Y2
Zhu, Y1
Guo, Y1
Wang, Z1
Yang, Y1
Ding, G1
Lin, J1
Komatsu, M1
Funakoshi, T1
Aki, T1
Unuma, K1
Uemura, K1
Jhuang, JR1
Chiu, PC1
Hsieh, TC1
Lee, WC1
Liao, CI1
Fang, HC1
Lee, PT1
Hsu, CY1
Chen, CL1
Huang, CW1
Chen, XY1
Ou, SH1
Tsai, CT1
Chou, KJ1
Radic Savic, Z1
Coric, V1
Vidovic, S1
Vidovic, V1
Becarevic, J1
Milovac, I1
Reljic, Z1
Mirjanic-Azaric, B1
Skrbic, R1
Gajanin, R1
Matic, M1
Simic, T1
Shao, IH1
Chang, YH1
Pang, ST1
Dika, Ž1
Arlt, VM2
Stiborova, M1
Pavlović, NM1
Nikolić, J1
Colet, JM1
Vanherweghem, JL2
Nortier, JL2
Fang, D1
Zhang, L3
Li, X1
Xiong, G1
Chen, X1
Han, W1
He, Z1
Zhou, L2
Zhang, A1
Shang, D1
Shi, R1
Fu, F1
Soria, F1
Shariat, SF1
Lerner, SP1
Fritsche, HM1
Rink, M1
Kassouf, W1
Spiess, PE1
Lotan, Y1
Ye, D1
Fernández, MI1
Kikuchi, E1
Chade, DC1
Babjuk, M1
Thalmann, GN1
Yuan, M1
Shi, YB1
Li, ZH1
Xia, M1
Ji, GZ1
Xu, GX1
Han, Y1
Stefanovic, V1
Polenakovic, M1
Toncheva, D1
Moriya, M3
Sidorenko, VS1
Edwards, KL1
Gnatenko, DV1
Wu, L2
Turesky, RJ2
Wu, XR1
Schetter, AJ1
Harris, CC1
Cao, YL1
Li, WG1
Fu, FT1
Wang, X1
Shi, XH1
Huang, CY1
Shun, CT1
Tai, HC1
Huang, KH1
Wang, SM1
Lee, YJ1
Kanaan, N1
Cosyns, JP2
Jadoul, M2
Goffin, E1
Laing, C1
Hamour, S1
Sheaff, M1
Miller, R1
Woolfson, R1
Shibutani, S1
Miller, F1
Moll, U1
Suzuki, N1
Fernandes, A1
Rosenquist, T1
Medverec, Z1
Jakovina, K1
Brdar, B1
Goodenough, AK1
Rieger, R1
Vukelić, M1
Squifflet, JP1
Wese, FX1
van Ypersele de Strihou, C1
De Broe, ME1
Lord, GM1
Cook, T1
Schmeiser, HH1
Williams, G1
Pusey, CD1
Debelle, FD1
De Prez, EG1
Garbar, CH1
Vienne, AR1
Salmon, IJ1
Deschodt-Lanckman, MM1
Lampert, N1
Xu, Y1
Nortier, J1

Reviews

5 reviews available for aristolochic acid i and Carcinoma, Transitional Cell

ArticleYear
Aristolochic acid-containing Chinese herbal medicine and upper urinary tract urothelial carcinoma in Taiwan: a narrative review.
    World journal of urology, 2023, Volume: 41, Issue:4

    Topics: Aristolochic Acids; Carcinogens; Carcinoma, Transitional Cell; DNA Adducts; Drugs, Chinese Herbal; F

2023
Recent advances in upper tract urothelial carcinomas: From bench to clinics.
    International journal of urology : official journal of the Japanese Urological Association, 2019, Volume: 26, Issue:2

    Topics: Animals; Antineoplastic Agents; Aristolochic Acids; Arsenic; Carcinogens; Carcinoma, Transitional Ce

2019
Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid.
    Seminars in nephrology, 2019, Volume: 39, Issue:3

    Topics: Animals; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Carcinoma, Transitional

2019
Epidemiology, diagnosis, preoperative evaluation and prognostic assessment of upper-tract urothelial carcinoma (UTUC).
    World journal of urology, 2017, Volume: 35, Issue:3

    Topics: Aristolochic Acids; Carcinoma, Transitional Cell; Colorectal Neoplasms, Hereditary Nonpolyposis; Hum

2017
Urothelial carcinoma associated with Balkan endemic nephropathy. A worldwide disease.
    Pathologie-biologie, 2011, Volume: 59, Issue:5

    Topics: Aristolochic Acids; Balkan Nephropathy; Carcinoma, Transitional Cell; Diet; DNA Adducts; Endemic Dis

2011

Other Studies

23 other studies available for aristolochic acid i and Carcinoma, Transitional Cell

ArticleYear
Molecular profiles and urinary biomarkers of upper tract urothelial carcinomas associated with aristolochic acid exposure.
    International journal of cancer, 2022, 01-15, Volume: 150, Issue:2

    Topics: Aristolochic Acids; Biomarkers, Tumor; Carcinoma, Transitional Cell; Exome; Follow-Up Studies; Gene

2022
Aristolochic acid: What urologists should know.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2022, Mar-30, Volume: 94, Issue:1

    Topics: Aristolochic Acids; Carcinoma, Transitional Cell; Humans; Urinary Bladder Neoplasms; Urologists

2022
De novo upper tract urothelial carcinoma after renal transplantation: a single-center experience in China.
    BMC urology, 2023, Feb-20, Volume: 23, Issue:1

    Topics: Carcinoma, Transitional Cell; Humans; Kidney Transplantation; Neoplasm Recurrence, Local; Prognosis;

2023
Aristolochic acid induces an inflammatory response with prostaglandin E2 production and apoptosis in NRK-52E proximal tubular cells.
    Toxicology letters, 2023, Apr-01, Volume: 378

    Topics: Animals; Apoptosis; Aristolochic Acids; Carcinoma, Transitional Cell; Cell Line; Cyclooxygenase 2; D

2023
Latency period of aristolochic acid-induced upper urinary tract urothelial carcinoma.
    Frontiers in public health, 2023, Volume: 11

    Topics: Adult; Carcinoma, Transitional Cell; Cohort Studies; Female; Humans; Kidney Neoplasms; Male; Middle

2023
Trends in the incidence of urothelial carcinoma in Taiwan after the ban on aristolochic acid-containing Chinese herbal preparations, 2001-2018: a national population-based cohort study.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:11

    Topics: Carcinoma, Transitional Cell; Cohort Studies; Humans; Incidence; Taiwan; Urinary Bladder Neoplasms;

2023
    Medicina (Kaunas, Lithuania), 2023, Aug-04, Volume: 59, Issue:8

    Topics: Balkan Nephropathy; Carcinoma, Transitional Cell; Female; Glutathione Peroxidase; Humans; Kelch-Like

2023
Risk factors and treatment outcomes of new contralateral upper urinary urothelial carcinoma after nephroureterectomy: the experiences of a large Chinese center.
    Journal of cancer research and clinical oncology, 2014, Volume: 140, Issue:3

    Topics: Aged; Aristolochic Acids; Carcinogens; Carcinoma, Transitional Cell; China; Female; Humans; Kaplan-M

2014
A retrospective review of patients with urothelial cancer in 3,370 recipients after renal transplantation: a single-center experience.
    World journal of urology, 2015, Volume: 33, Issue:5

    Topics: Adult; Aged; Aristolochic Acids; Carcinoma, Transitional Cell; China; Cystectomy; Drugs, Chinese Her

2015
De novo urothelial carcinoma in kidney transplant patients with end-stage aristolochic acid nephropathy in China.
    Transplantation proceedings, 2009, Volume: 41, Issue:5

    Topics: Adult; Aged; Antiviral Agents; Aristolochic Acids; Cadaver; Carcinoma, Transitional Cell; China; Fem

2009
Aristolochic acid-associated urothelial cancer in Taiwan.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, May-22, Volume: 109, Issue:21

    Topics: Adult; Aged; Aged, 80 and over; Aristolochic Acids; Carcinoma, Renal Cell; Carcinoma, Transitional C

2012
Tumor suppressor p53 (TP53) at the crossroads of the exposome and the cancer genome.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, May-22, Volume: 109, Issue:21

    Topics: Aristolochic Acids; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Fema

2012
Transitional cell carcinoma associated with aristolochic acid nephropathy: most common cancer in chronic hemodialysis patients in China.
    Chinese medical journal, 2012, Volume: 125, Issue:24

    Topics: Adult; Aged; Aged, 80 and over; Aristolochic Acids; Carcinoma, Transitional Cell; China; Female; Hum

2012
Aristolochic acid-induced upper tract urothelial carcinoma in Taiwan: clinical characteristics and outcomes.
    International journal of cancer, 2013, Volume: 133, Issue:1

    Topics: Adenine; Adult; Age Factors; Aged; Aged, 80 and over; Aristolochic Acids; Carcinogens; Carcinoma, Tr

2013
The importance of a histology-based diagnosis of interstitial nephropathy in two patients with renal insufficiency.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:2

    Topics: Aged; Aristolochic Acids; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Female; Humans; Kidne

2003
Chinese herbal uropathy and nephropathy.
    Lancet (London, England), 2006, Jul-22, Volume: 368, Issue:9532

    Topics: Adult; Aristolochic Acids; Carcinogens; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Humans;

2006
Aristolochic acid and the etiology of endemic (Balkan) nephropathy.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jul-17, Volume: 104, Issue:29

    Topics: Aristolochic Acids; Balkan Nephropathy; Carcinoma, Transitional Cell; DNA Adducts; Female; Humans; K

2007
Urothelial lesions in Chinese-herb nephropathy.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:6

    Topics: Adult; Aristolochic Acids; Carcinogens; Carcinoma in Situ; Carcinoma, Transitional Cell; Drugs, Chin

1999
On a nephrotoxic and carcinogenic slimming regimen.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1999, Volume: 33, Issue:6

    Topics: Analgesics; Animals; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Carcinoma, Transitional Ce

1999
Urothelial malignant disease and Chinese herbal nephropathy.
    Lancet (London, England), 2001, Nov-03, Volume: 358, Issue:9292

    Topics: Aristolochic Acids; Carcinogens; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Female; Humans

2001
Aristolochic acids induce chronic renal failure with interstitial fibrosis in salt-depleted rats.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:2

    Topics: Animals; Aristolochic Acids; Body Weight; Carcinoma, Transitional Cell; Dose-Response Relationship,

2002
Chinese herbal nephropathy.
    Lancet (London, England), 2002, Mar-02, Volume: 359, Issue:9308

    Topics: Aristolochic Acids; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Humans; Kidney Failure, Chr

2002
[Renal interstitial fibrosis and urotelial carcinomas after ingestion of a Chinese herb (Aristolochia fangchi)].
    Nephrologie, 2002, Volume: 23, Issue:1

    Topics: Anti-Obesity Agents; Aristolochia; Aristolochic Acids; Atrophy; Biomarkers; Carcinogens; Carcinoma,

2002