aristolochic acid i has been researched along with Cancer of Stomach in 7 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The rats of Radix Aristolochice showed serious toxic responses of renal tubule atrophy and necrosis, meanwhile, the levels of BUN, Cr and NAG were increased obviously." | 1.34 | [Nephrotoxicity of Radix Aristolochice and it's substitution material Radix Inulae in rats]. ( Li, LD; Liu, YY; Qiao, HX; Wu, LM, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Liang, A | 1 |
| Gao, S | 1 |
| Hui, L | 1 |
| Liu, T | 1 |
| Cao, C | 1 |
| Zhao, Y | 1 |
| Hao, R | 1 |
| Yi, Y | 1 |
| Guo, J | 1 |
| Mengs, U | 1 |
| Fernando, RC | 2 |
| Schmeiser, HH | 3 |
| Scherf, HR | 1 |
| Wiessler, M | 2 |
| Hadjiolov, D | 1 |
| Hadjiolov, N | 1 |
| Pirajnov, G | 1 |
| Cosyns, JP | 1 |
| Goebbels, RM | 1 |
| Liberton, V | 1 |
| Bieler, CA | 1 |
| Bernard, AM | 1 |
| Qiao, HX | 2 |
| Liu, YY | 2 |
| Wu, LM | 2 |
| Li, LD | 2 |
7 other studies available for aristolochic acid i and Cancer of Stomach
| Article | Year |
|---|---|
[Development of gastric precancerous lesion animal model].
Topics: Animals; Aristolochia; Aristolochic Acids; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Ma | 2012 |
On the histopathogenesis of rat forestomach carcinoma caused by aristolochic acid.
Topics: Animals; Antineoplastic Agents; Aristolochic Acids; Hyperplasia; Male; Neoplasms, Experimental; Papi | 1983 |
Formation and persistence of specific purine DNA adducts by 32P-postlabelling in target and non-target organs of rats treated with aristolochic acid I.
Topics: Animals; Aristolochic Acids; Carcinogens; Deoxyadenosines; Deoxyguanosine; DNA; DNA Damage; Gastric | 1993 |
Effect of diallyl sulfide on aristolochic acid-induced forestomach carcinogenesis in rats.
Topics: Allyl Compounds; Animals; Antineoplastic Agents; Aristolochic Acids; Carcinogens; DNA; DNA Damage; D | 1993 |
Chinese herbs nephropathy-associated slimming regimen induces tumours in the forestomach but no interstitial nephropathy in rats.
Topics: Animals; Anti-Obesity Agents; Aristolochic Acids; Carcinogens; Drugs, Chinese Herbal; Female; Fibrin | 1998 |
[Hepatic and renal injury induced by Radix Aristolochiae or Guanxin Suhe Wan for a long-term in rats].
Topics: Animals; Aristolochia; Drugs, Chinese Herbal; Kidney; Liver; Male; Rats; Rats, Sprague-Dawley; Stoma | 2008 |
[Nephrotoxicity of Radix Aristolochice and it's substitution material Radix Inulae in rats].
Topics: Acetylglucosaminidase; Animals; Aristolochia; Blood Urea Nitrogen; Creatinine; Drugs, Chinese Herbal | 2007 |