aristolochic acid i has been researched along with Cancer of Prostate in 3 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Additionally, we allude to some of the cancer types where there is molecular epidemiological evidence that these agents are aetiological risk factors." | 2.58 | Carcinogens and DNA damage. ( Barnes, JL; John, K; Martin, FL; Poirier, MC; Zubair, M, 2018) |
| "Together, in PC3 human prostate cancer cells, thapsigargin induced [Ca²⁺](i) rises by causing phospholipase C-independent Ca²⁺ release from the endoplasmic reticulum and Ca²⁺ influx via phospholipase A2-sensitive Ca²⁺ channels." | 1.37 | Effect of thapsigargin on Ca²+ fluxes and viability in human prostate cancer cells. ( Chang, HT; Chen, IS; Chou, CT; Ho, CM; Huang, JK; Jan, CR; Kuo, CC; Liao, WC; Lin, KL; Liu, SI; Lu, YC; Shu, SS; Tsai, JY; Wang, JL, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JL | 1 |
| Zubair, M | 1 |
| John, K | 1 |
| Poirier, MC | 1 |
| Martin, FL | 1 |
| Huang, JK | 1 |
| Chou, CT | 1 |
| Chang, HT | 1 |
| Shu, SS | 1 |
| Kuo, CC | 2 |
| Tsai, JY | 2 |
| Liao, WC | 1 |
| Wang, JL | 1 |
| Lin, KL | 1 |
| Lu, YC | 1 |
| Chen, IS | 1 |
| Liu, SI | 1 |
| Ho, CM | 1 |
| Jan, CR | 2 |
| Shieh, P | 1 |
| Kuo, DH | 1 |
| Chen, FA | 1 |
1 review available for aristolochic acid i and Cancer of Prostate
| Article | Year |
|---|---|
Carcinogens and DNA damage.
Topics: Amines; Animals; Aristolochic Acids; Benzo(a)pyrene; Carcinogens; Cross-Linking Reagents; Diet; DNA; | 2018 |
2 other studies available for aristolochic acid i and Cancer of Prostate
| Article | Year |
|---|---|
Effect of thapsigargin on Ca²+ fluxes and viability in human prostate cancer cells.
Topics: Apoptosis; Aristolochic Acids; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Survival; Estrenes | 2011 |
Effect of m-3M3FBS on Ca²⁺ movement in PC3 human prostate cancer cells.
Topics: Adenocarcinoma; Aristolochic Acids; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Line, | 2010 |