aristolochic acid i has been researched along with Balkan Endemic Nephropathy in 57 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Described in the 1950s, Balkan Endemic Nephropathy (BEN) has been recognized as a chronic kidney disease (CKD) with clinical peculiarities and multiple etiological factors." | 6.82 | Aristolochic acid I as an emerging biogenic contaminant involved in chronic kidney diseases: A comprehensive review on exposure pathways, environmental health issues and future challenges. ( Drăghia, LP; Lukinich-Gruia, AT; Milovanović, D; Nortier, J; Păunescu, V; Pavlović, NM; Popović, M; Tatu, CA, 2022) |
| "We evaluated the role of exposure analysis in assessing whether ochratoxin A or aristolochic acid are the agents responsible for causing Balkan endemic nephropathy." | 4.84 | Role of exposure analysis in solving the mystery of Balkan endemic nephropathy. ( Long, DT; Voice, TC, 2007) |
| "Aristolochic acid I (AAI) is a potent nephrotoxic and carcinogenic compound produced by plants of the Aristolochiaceae family and thoroughly investigated as a main culprit in the etiology of Balkan endemic nephropathy (BEN)." | 4.02 | Aristolochic acid I: an investigation into the role of food crops contamination, as a potential natural exposure pathway. ( Drăghia, LP; Lukinich-Gruia, AT; Oprean, C; Păunescu, V; Pavlović, NM; Tatu, CA, 2021) |
| "Exposure to aristolochic acid I (AAI) can lead to aristolochic acid nephropathy (AAN), Balkan endemic nephropathy (BEN) and urothelial cancer." | 3.81 | Baicalin Protects Mice from Aristolochic Acid I-Induced Kidney Injury by Induction of CYP1A through the Aromatic Hydrocarbon Receptor. ( Feng, C; Gong, L; Li, C; Luan, Y; Qi, X; Ren, J; Wang, K; Xie, X; Xing, G; Yao, J; Zhu, X, 2015) |
| "Exposure to aristolochic acid I (AAI) is associated with aristolochic acid nephropathy, Balkan endemic nephropathy, and urothelial cancer." | 3.77 | Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice. ( Arlt, VM; Bárta, F; Evans, JD; Frei, E; Levová, K; Nebert, DW; Phillips, DH; Schmeiser, HH; Shi, Z; Stiborová, M, 2011) |
| " Even tough numerous dilemmas and conflicting opinions regarding BEN etiology are encountered in literature, prevailing theory is that BEN is caused by chronic poisoning with aristolochic acid ingested by food in people with genetic predisposition to this disease." | 3.76 | Early detection of Balkan endemic nephropathy in Bosanska Posavina. ( Mesić, E, 2010) |
| "The role of aristolochic acid in the etiology of Balkan endemic nephropathy (BEN) and associated upper urothelial carcinoma (UUC) was recently confirmed." | 3.75 | Molecular markers in upper urothelial carcinoma associated to Balkan endemic nephropathy. Aristolochic acid as the major risk factor of the worldwide disease. ( Hattori, T; Jankovic Velickovic, L; Stefanovic, V, 2009) |
| "To find out whether ochratoxin A (OTA), citrinin (CIT), aristolochic acids (AA) are etiologic agents of Balkan endemic nephropathy (BEN) or Chinese herbal nephrotoxicity, and associated urinary tract tumor (UTT), we have compared (i) in human kidney cell culture, the DNA adduct formation and persistence of OTA/CIT and AA adducts (ii) analyzed DNA adduct in several tumors from human kidney suspected to be exposed to either OTA and CIT, or AAs (iii) analyzed OTA, CIT, and AA in food." | 3.74 | New molecular and field evidences for the implication of mycotoxins but not aristolochic acid in human nephropathy and urinary tract tumor. ( Castegnaro, M; Manderville, R; Peraica, M; Pfohl-Leszkowicz, A; Stefanovic, V; Tozlovanu, M, 2007) |
| "Described in the 1950s, Balkan Endemic Nephropathy (BEN) has been recognized as a chronic kidney disease (CKD) with clinical peculiarities and multiple etiological factors." | 2.82 | Aristolochic acid I as an emerging biogenic contaminant involved in chronic kidney diseases: A comprehensive review on exposure pathways, environmental health issues and future challenges. ( Drăghia, LP; Lukinich-Gruia, AT; Milovanović, D; Nortier, J; Păunescu, V; Pavlović, NM; Popović, M; Tatu, CA, 2022) |
| "Balkan endemic nephropathy is a chronic tubulointerstitial disease with insidious onset, slowly progressing to end-stage renal disease and frequently associated with urothelial carcinoma of the upper urinary tract (UTUC)." | 2.61 | Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid. ( Arlt, VM; Colet, JM; Dika, Ž; Jelaković, B; Nikolić, J; Nortier, JL; Pavlović, NM; Stiborova, M; Vanherweghem, JL, 2019) |
| " In contrast, the molecular mechanism of renal interstitial fibrosis in humans after chronic administration of AA remains to be explored." | 2.41 | Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. ( Arlt, VM; Schmeiser, HH; Stiborova, M, 2002) |
| "Balkan endemic nephropathy is nowadays considered as an aristolochic acid nephropathy." | 1.42 | Herbs and hazards: risk of aristolochic acid nephropathy in Iran. ( Ardalan, MR; Jouyban, A; Khodaie, L; Nasri, H, 2015) |
| "Chinese herbs nephropathy (CHN) and Balkan endemic nephropathy (BEN) are chronic tubulointerstitial renal diseases associated with urothelial carcinoma." | 1.38 | Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy. ( De Broe, ME, 2012) |
| "Similarities of CHN to the Balkan endemic nephropathy (BEN) have led to the hypothesis of a common etiological agent for both diseases." | 1.31 | Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patients with Chinese herbs nephropathy. ( Arlt, VM; Cosyns, J; Pfohl-Leszkowicz, A; Schmeiser, HH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.75) | 18.2507 |
| 2000's | 15 (26.32) | 29.6817 |
| 2010's | 31 (54.39) | 24.3611 |
| 2020's | 10 (17.54) | 2.80 |
| Authors | Studies |
|---|---|
| Lukinich-Gruia, AT | 2 |
| Nortier, J | 1 |
| Pavlović, NM | 10 |
| Milovanović, D | 2 |
| Popović, M | 1 |
| Drăghia, LP | 2 |
| Păunescu, V | 3 |
| Tatu, CA | 4 |
| Zhang, J | 3 |
| Chan, KJ | 1 |
| Chan, W | 9 |
| Chan, CK | 6 |
| Chiang, SY | 1 |
| Wey, MT | 1 |
| Luo, YS | 1 |
| Shih, WC | 1 |
| Chimeddulam, D | 1 |
| Hsu, PC | 1 |
| Huang, HF | 1 |
| Tsai, TH | 1 |
| Wu, KY | 1 |
| Radic Savic, Z | 1 |
| Coric, V | 1 |
| Vidovic, S | 1 |
| Vidovic, V | 1 |
| Becarevic, J | 1 |
| Milovac, I | 1 |
| Reljic, Z | 1 |
| Mirjanic-Azaric, B | 1 |
| Skrbic, R | 1 |
| Gajanin, R | 1 |
| Matic, M | 1 |
| Simic, T | 1 |
| Rebhan, K | 1 |
| Ertl, IE | 1 |
| Shariat, SF | 1 |
| Grollman, AP | 8 |
| Rosenquist, T | 2 |
| Oprean, C | 2 |
| Guo, W | 1 |
| Sun, Z | 1 |
| Orem, WH | 1 |
| Radulović, NS | 1 |
| Gruia, AT | 1 |
| Ivan, A | 1 |
| Cean, A | 1 |
| Cristea, M | 1 |
| Draghia, L | 1 |
| Damiescu, R | 1 |
| Jelaković, B | 9 |
| Dika, Ž | 2 |
| Arlt, VM | 11 |
| Stiborova, M | 10 |
| Nikolić, J | 2 |
| Colet, JM | 1 |
| Vanherweghem, JL | 3 |
| Nortier, JL | 5 |
| Karanović, S | 4 |
| Lela, IV | 1 |
| Dickman, KG | 3 |
| Peić, AK | 1 |
| Dittrich, D | 2 |
| Knežević, M | 1 |
| Matijević, V | 2 |
| Fernandes, AS | 1 |
| Miller, F | 3 |
| Gökmen, MR | 2 |
| Cosyns, JP | 2 |
| Phillips, DH | 5 |
| Schmeiser, HH | 10 |
| Simmonds, MS | 1 |
| Cook, HT | 1 |
| Lord, GM | 3 |
| Cohen, J | 1 |
| Singh, R | 1 |
| Gamboa da Costa, G | 1 |
| Sennesael, J | 1 |
| Cassuto-Viguier, E | 1 |
| Ambrosetti, D | 1 |
| Rorive, S | 1 |
| Pozdzik, A | 1 |
| Castells, X | 1 |
| Tomić, K | 2 |
| Ardin, M | 1 |
| Zavadil, J | 1 |
| Vuković Lela, I | 1 |
| Kos, J | 2 |
| Dickman, K | 1 |
| Šekoranja, M | 1 |
| Poljičanin, T | 1 |
| Mišić, M | 1 |
| Premužić, V | 1 |
| Abramović, M | 1 |
| Miletić Medved, M | 1 |
| Cvitković, A | 1 |
| Edwards, K | 1 |
| Fuček, M | 1 |
| Leko, N | 1 |
| Teskera, T | 1 |
| Laganović, M | 1 |
| Čvorišćec, D | 1 |
| Ardalan, MR | 1 |
| Khodaie, L | 1 |
| Nasri, H | 1 |
| Jouyban, A | 1 |
| Fogazzi, GB | 1 |
| Bellincioni, C | 1 |
| Wang, K | 1 |
| Feng, C | 1 |
| Li, C | 1 |
| Yao, J | 1 |
| Xie, X | 1 |
| Gong, L | 1 |
| Luan, Y | 1 |
| Xing, G | 1 |
| Zhu, X | 1 |
| Qi, X | 1 |
| Ren, J | 1 |
| Barta, F | 2 |
| Levova, K | 3 |
| Hodek, P | 1 |
| Veale, EL | 1 |
| Mathie, A | 1 |
| Slade, N | 3 |
| Moll, UM | 1 |
| Brdar, B | 3 |
| Zorić, A | 1 |
| Stefanovic, V | 4 |
| Polenakovic, M | 2 |
| Toncheva, D | 3 |
| Jankovic Velickovic, L | 1 |
| Hattori, T | 1 |
| Mesić, E | 1 |
| Soderland, P | 1 |
| Lovekar, S | 1 |
| Weiner, DE | 1 |
| Brooks, DR | 1 |
| Kaufman, JS | 1 |
| Gluhovschi, G | 1 |
| Margineanu, F | 1 |
| Kaycsa, A | 1 |
| Velciov, S | 1 |
| Gluhovschi, C | 1 |
| Bob, F | 1 |
| Petrica, L | 1 |
| Bozdog, G | 1 |
| Dumitru, S | 1 |
| Olosz, E | 1 |
| Modalca, M | 1 |
| Pitt, JI | 1 |
| Shi, Z | 1 |
| Evans, JD | 1 |
| Frei, E | 2 |
| Nebert, DW | 2 |
| Vuković-Lela, I | 1 |
| Edwards, KL | 1 |
| Turesky, RJ | 3 |
| Stipančić, Ž | 1 |
| De Broe, ME | 2 |
| Moserova, M | 1 |
| Wooding, SP | 1 |
| Atanasova, S | 2 |
| Gunn, HC | 1 |
| Staneva, R | 1 |
| Dimova, I | 1 |
| Ferluga, D | 1 |
| Pfohl-Leszkowicz, A | 3 |
| Vukelic, M | 2 |
| Ceovic, S | 1 |
| vom Brocke, J | 1 |
| Simões, ML | 1 |
| Hollstein, M | 1 |
| Long, DT | 1 |
| Voice, TC | 1 |
| Shibutani, S | 1 |
| Moriya, M | 1 |
| Wu, L | 1 |
| Moll, U | 1 |
| Suzuki, N | 1 |
| Fernandes, A | 1 |
| Medverec, Z | 1 |
| Jakovina, K | 1 |
| Goodenough, AK | 1 |
| Rieger, R | 1 |
| Lincoln, T | 1 |
| Tozlovanu, M | 1 |
| Manderville, R | 1 |
| Peraica, M | 2 |
| Castegnaro, M | 1 |
| Domijan, AM | 1 |
| Sarić, M | 1 |
| Debelle, FD | 1 |
| Cosyns, J | 1 |
| Chan, KKJ | 2 |
| Tung, KK | 1 |
| Li, W | 3 |
| Wong, YL | 1 |
| Chan, HW | 1 |
| Liu, Y | 1 |
| Hu, Q | 1 |
| Liu, J | 1 |
| Deng, K | 1 |
| Wang, Y | 1 |
| Milosavljević, B | 1 |
| Kostić, EN | 1 |
| Yun, BH | 1 |
| Rosenquist, TA | 1 |
| Sidorenko, V | 1 |
| Iden, CR | 1 |
| Chen, CH | 1 |
| Pu, YS | 1 |
| Bonala, R | 1 |
| Johnson, F | 1 |
| Hranjec, T | 1 |
| Kovac, A | 1 |
| Mao, W | 1 |
| Chen, JJ | 1 |
14 reviews available for aristolochic acid i and Balkan Endemic Nephropathy
| Article | Year |
|---|---|
Aristolochic acid I as an emerging biogenic contaminant involved in chronic kidney diseases: A comprehensive review on exposure pathways, environmental health issues and future challenges.
Topics: Aristolochic Acids; Balkan Nephropathy; Environmental Health; Female; Humans; Male; Renal Insufficie | 2022 |
Balkan Endemic Nephropathy and the Causative Role of Aristolochic Acid.
Topics: Animals; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Carcinoma, Transitional | 2019 |
The epidemiology, diagnosis, and management of aristolochic acid nephropathy: a narrative review.
Topics: Aristolochic Acids; Balkan Nephropathy; Humans; Kidney Diseases; Plant Preparations; Risk Factors; U | 2013 |
Balkan endemic nephropathy: an update on its aetiology.
Topics: Animals; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Carcinogens, Environmental; Confoundi | 2016 |
p53 mutations as fingerprints for aristolochic acid: an environmental carcinogen in endemic (Balkan) nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Carcinogens, Environmental; Humans; Mutagens; Mutation; Tumo | 2009 |
Urothelial carcinoma associated with Balkan endemic nephropathy. A worldwide disease.
Topics: Aristolochic Acids; Balkan Nephropathy; Carcinoma, Transitional Cell; Diet; DNA Adducts; Endemic Dis | 2011 |
Chronic kidney disease associated with environmental toxins and exposures.
Topics: Aristolochic Acids; Balkan Nephropathy; Chronic Disease; Drugs, Chinese Herbal; Endemic Diseases; En | 2010 |
Aristolochic acid nephropathy: Harbinger of a global iatrogenic disease.
Topics: Aristolochic Acids; Balkan Nephropathy; DNA Adducts; Humans; Iatrogenic Disease; Kidney Cortex; Kidn | 2013 |
Aristolochic acid as a probable human cancer hazard in herbal remedies: a review.
Topics: Animals; Aristolochic Acids; Balkan Nephropathy; Carcinogens; DNA Adducts; Drugs, Chinese Herbal; He | 2002 |
Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.
Topics: Animals; Aristolochic Acids; Balkan Nephropathy; Cell Transformation, Neoplastic; DNA Adducts; Genes | 2007 |
Role of exposure analysis in solving the mystery of Balkan endemic nephropathy.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Croatia; Environmental Exposure; Goiter, Endem | 2007 |
Mycotoxic and aristolochic acid theories of the development of endemic nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Humans; Ochratoxins | 2008 |
Aristolochic acid nephropathy: a worldwide problem.
Topics: Animals; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Belgium; Cell Transformation, Neoplas | 2008 |
Etiology of Balkan endemic nephropathy and associated urothelial cancer.
Topics: Aristolochia; Balkan Nephropathy; Disease Susceptibility; Environmental Exposure; Genetic Markers; H | 2006 |
43 other studies available for aristolochic acid i and Balkan Endemic Nephropathy
| Article | Year |
|---|---|
Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Coal; DNA Adducts; Esters; Female; Humans; Kidney Diseases; | 2022 |
Effects of Diet on Aristolochic Acid-DNA Adduct Formation: Implications for Balkan Endemic Nephropathy Etiology.
Topics: Aristolochic Acids; Balkan Nephropathy; Diet; DNA Adducts; Humans; Kidney Diseases; Neoplasms | 2023 |
Simultaneous toxicokinetic studies of aristolochic acid I and II and aristolactam I and II using a newly-developed microdialysis liquid chromatography-tandem mass spectrometry.
Topics: Animals; Aristolochic Acids; Balkan Nephropathy; Chromatography, Liquid; Kidney Diseases; Microdialy | 2023 |
Topics: Balkan Nephropathy; Carcinoma, Transitional Cell; Female; Glutathione Peroxidase; Humans; Kelch-Like | 2023 |
Aristolochic acid and its effect on different cancers in uro-oncology.
Topics: Aristolochic Acids; Balkan Nephropathy; Carcinogens; DNA Adducts; Drugs, Chinese Herbal; Humans; Uri | 2020 |
Aristolochic acid I: an investigation into the role of food crops contamination, as a potential natural exposure pathway.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Crops, Agricultural | 2021 |
Analysis of Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Soil and Food Grains from the Balkan Peninsula: Implication on DNA Adduct Formation by Aristolochic Acid I and Balkan Endemic Nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Balkan Peninsula; DNA Adducts; Esters; Humans; Phthalic Acid | 2021 |
Balkan endemic nephropathy and aristolochic acid I: an investigation into the role of soil and soil organic matter contamination, as a potential natural exposure pathway.
Topics: Aristolochic Acids; Balkan Nephropathy; Chromatography, High Pressure Liquid; Crops, Agricultural; E | 2018 |
Variation in presentation and presence of DNA adducts and p53 mutations in patients with endemic nephropathy--an environmental form of the aristolochic acid nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; DNA Adducts; Environmental Exposure; Genes, p53; Humans; Kid | 2013 |
A Balkan riddle's serendipitous solution.
Topics: Animals; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Croatia; Horse Diseases; Horses; Huma | 2014 |
Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy.
Topics: Adult; Aged; Aristolochic Acids; Balkan Nephropathy; Biomarkers; Chromatography, Thin Layer; DNA Add | 2014 |
Renal cell carcinomas of chronic kidney disease patients harbor the mutational signature of carcinogenic aristolochic acid.
Topics: Adult; Aged; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Carcinoma, Renal Cell; Exome; Fema | 2015 |
Chronic dietary exposure to aristolochic acid and kidney function in native farmers from a Croatian endemic area and Bosnian immigrants.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Agricultural Workers' Diseases; Agriculture; Alpha-Globu | 2015 |
Herbs and hazards: risk of aristolochic acid nephropathy in Iran.
Topics: Aristolochiaceae; Aristolochic Acids; Balkan Nephropathy; Humans; Iran; Phytotherapy; Plant Extracts | 2015 |
Aristolochia clematitis, the herb responsible for aristolochic acid nephropathy, in an uncultivated piece of land of an Italian nephrologist.
Topics: Adult; Aged; Aged, 80 and over; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Ethnobotany; F | 2015 |
Baicalin Protects Mice from Aristolochic Acid I-Induced Kidney Injury by Induction of CYP1A through the Aromatic Hydrocarbon Receptor.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aristolochic Acids; Balkan Ne | 2015 |
The effects of heavy metal ions, phthalates and ochratoxin A on oxidation of carcinogenic aristolochic acid I causing Balkan endemic nephropathy.
Topics: Animals; Aristolochic Acids; Arsenic; Balkan Nephropathy; Cadmium; Carcinogens; Chromatography, High | 2015 |
Aristolochic acid, a plant extract used in the treatment of pain and linked to Balkan endemic nephropathy, is a regulator of K2P channels.
Topics: Aristolochic Acids; Balkan Nephropathy; Cells, Cultured; Dose-Response Relationship, Drug; Humans; M | 2016 |
Molecular markers in upper urothelial carcinoma associated to Balkan endemic nephropathy. Aristolochic acid as the major risk factor of the worldwide disease.
Topics: Adult; Aged; Aged, 80 and over; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Biomarkers, Tu | 2009 |
Early detection of Balkan endemic nephropathy in Bosanska Posavina.
Topics: Adolescent; Adult; Aged; Aristolochic Acids; Balkan Nephropathy; Bosnia and Herzegovina; Child; Fema | 2010 |
Therapeutic remedies based on Aristolochia clematitis in the main foci of Balkan endemic nephropathy in Romania.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Beverages; Data Collection; Female; Humans; Pl | 2010 |
Chinese herbal medicines, aristolochic acid and Balkan endemic nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Drug Contamination; Drugs, Chinese Herbal; Food Contaminatio | 2011 |
Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.
Topics: Animals; Aristolochic Acids; Balkan Nephropathy; Biotransformation; Carcinogens; Cytochrome P-450 CY | 2011 |
Aristolactam-DNA adducts are a biomarker of environmental exposure to aristolochic acid.
Topics: Adult; Aged; Aged, 80 and over; Aristolochic Acids; Balkan Nephropathy; Biomarkers; Biotransformatio | 2012 |
Chinese herbs nephropathy and Balkan endemic nephropathy: toward a single entity, aristolochic acid nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Carcinogens, Environmental; Carcinoma; DNA Adducts; Environm | 2012 |
Aristolochic acid nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Carcinogens; Drugs, Chinese Herbal; Humans; Kidney Diseases; | 2012 |
NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I.
Topics: Animals; Aristolochic Acids; Balkan Nephropathy; Blotting, Western; Cell Line; Cytochrome P-450 CYP1 | 2012 |
Association of a bitter taste receptor mutation with Balkan Endemic Nephropathy (BEN).
Topics: Aged; Alleles; Aristolochic Acids; Balkan Nephropathy; Case-Control Studies; Cohort Studies; Female; | 2012 |
Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer?
Topics: Aged; Aristolochic Acids; Balkan Nephropathy; Carcinogens; DNA Adducts; Female; Humans; Middle Aged; | 2002 |
Aristolochic acid and the etiology of endemic (Balkan) nephropathy.
Topics: Aristolochic Acids; Balkan Nephropathy; Carcinoma, Transitional Cell; DNA Adducts; Female; Humans; K | 2007 |
Toxicology: danger in the diet.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Belgium; Croatia; Diet; Humans | 2007 |
New molecular and field evidences for the implication of mycotoxins but not aristolochic acid in human nephropathy and urinary tract tumor.
Topics: Aged; Aged, 80 and over; Anti-Obesity Agents; Aristolochic Acids; Balkan Nephropathy; Belgium; Bulga | 2007 |
On a nephrotoxic and carcinogenic slimming regimen.
Topics: Analgesics; Animals; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Carcinoma, Transitional Ce | 1999 |
Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patients with Chinese herbs nephropathy.
Topics: Adult; Animals; Anti-Obesity Agents; Aristolochic Acids; Balkan Nephropathy; Belgium; DNA Adducts; D | 2001 |
Liquid chromatography-tandem mass spectrometry analysis of aristolochic acids in soil samples collected from Serbia: Link to Balkan endemic nephropathy.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Chromatography, Liquid; Crops, Agricultural; H | 2020 |
Remediation of aristolochic acid-contaminated soil by an effective advanced oxidation process.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Balkan Peninsula; Humans; Hydrogen Peroxide; S | 2020 |
Cooking methods employing natural anti-oxidant food additives effectively reduced concentration of nephrotoxic and carcinogenic aristolochic acids in contaminated food grains.
Topics: Antioxidants; Aristolochia; Aristolochic Acids; Ascorbic Acid; Balkan Nephropathy; Carcinogens; Citr | 2018 |
Etiology of Balkan Endemic Nephropathy: An Update on Aristolochic Acids Exposure Mechanisms.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Crops, Agricultural; Humans; Soil Pollutants; | 2018 |
Uptake and Accumulation of Nephrotoxic and Carcinogenic Aristolochic Acids in Food Crops Grown in Aristolochia clematitis-Contaminated Soil and Water.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Carcinogens; Crops, Agricultural; Humans; Soil | 2016 |
Quantitation of Aristolochic Acids in Corn, Wheat Grain, and Soil Samples Collected in Serbia: Identifying a Novel Exposure Pathway in the Etiology of Balkan Endemic Nephropathy.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Environmental Exposure; Humans; Serbia; Soil; | 2016 |
Biomonitoring of aristolactam-DNA adducts in human tissues using ultra-performance liquid chromatography/ion-trap mass spectrometry.
Topics: Adult; Aged; Animals; Aristolochia; Aristolochic Acids; Balkan Nephropathy; Chromatography, Liquid; | 2012 |
Endemic nephropathy: the case for chronic poisoning by aristolochia.
Topics: Aristolochia; Balkan Nephropathy; Case-Control Studies; Chi-Square Distribution; Chronic Disease; Cr | 2005 |
Role of environmental toxins in endemic (Balkan) nephropathy. October 2006, Zagreb, Croatia.
Topics: Aristolochia; Aristolochic Acids; Balkan Nephropathy; Humans; Toxins, Biological; Urologic Neoplasms | 2007 |