aristolochic acid i has been researched along with American Trypanosomiasis in 1 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The need for novel drugs for American trypanosomiasis is evident, and these secondary metabolites from A." | 1.36 | Antitrypanosomal activity of a diterpene and lignans isolated from Aristolochia cymbifera. ( Carvalho, CS; Lorenzi, H; Reimão, JQ; Sartorelli, P; Tempone, AG, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sartorelli, P | 1 |
| Carvalho, CS | 1 |
| Reimão, JQ | 1 |
| Lorenzi, H | 1 |
| Tempone, AG | 1 |
1 other study available for aristolochic acid i and American Trypanosomiasis
| Article | Year |
|---|---|
Antitrypanosomal activity of a diterpene and lignans isolated from Aristolochia cymbifera.
Topics: Animals; Aristolochia; Chagas Disease; Diterpenes; Hemolytic Agents; Inhibitory Concentration 50; Li | 2010 |