Page last updated: 2024-10-22

aristolochic acid i and Aging

aristolochic acid i has been researched along with Aging in 2 studies

aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Generally, renal aging is accompanied by renal fibrosis, which is the final common pathway of chronic kidney diseases."5.62Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice. ( Abe, E; Atobe, Y; Azushima, K; Funakoshi, K; Kanaoka, T; Kinguchi, S; Suzuki, T; Taguchi, S; Tamura, K; Tanaka, S; Tsukamoto, S; Uneda, K; Urate, S; Wakui, H; Yamaji, T; Yamashita, A, 2021)
"Generally, renal aging is accompanied by renal fibrosis, which is the final common pathway of chronic kidney diseases."1.62Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice. ( Abe, E; Atobe, Y; Azushima, K; Funakoshi, K; Kanaoka, T; Kinguchi, S; Suzuki, T; Taguchi, S; Tamura, K; Tanaka, S; Tsukamoto, S; Uneda, K; Urate, S; Wakui, H; Yamaji, T; Yamashita, A, 2021)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Urate, S1
Wakui, H1
Azushima, K1
Yamaji, T1
Suzuki, T1
Abe, E1
Tanaka, S1
Taguchi, S1
Tsukamoto, S1
Kinguchi, S1
Uneda, K1
Kanaoka, T1
Atobe, Y1
Funakoshi, K1
Yamashita, A1
Tamura, K1
Watson, SN1
Wright, N1
Hermann, PM1
Wildering, WC1

Other Studies

2 other studies available for aristolochic acid i and Aging

ArticleYear
Aristolochic Acid Induces Renal Fibrosis and Senescence in Mice.
    International journal of molecular sciences, 2021, Nov-18, Volume: 22, Issue:22

    Topics: Aging; Animals; Aristolochic Acids; beta-Galactosidase; Collagen; Cyclin-Dependent Kinase Inhibitor

2021
Phospholipase A₂: the key to reversing long-term memory impairment in a gastropod model of aging.
    Neurobiology of aging, 2013, Volume: 34, Issue:2

    Topics: Aging; Amidines; Animals; Aristolochic Acids; Conditioning, Operant; Lymnaea; Memory Disorders; Memo

2013