aristolochic acid i has been researched along with Adverse Drug Event in 5 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Toxic effects from chronic or cumulative dosing are difficult to detect in the traditional setting and recent reports have demonstrated the health problems from Aristolochia species." | 2.46 | Toxicological risks of Chinese herbs. ( Shaw, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tian, JZ | 1 |
| Liu, SY | 1 |
| Gao, Y | 1 |
| Zhang, BL | 1 |
| Liang, AH | 1 |
| Song, HB | 1 |
| Ren, JT | 1 |
| Yang, L | 1 |
| Guo, XX | 1 |
| Du, XX | 1 |
| Stegelmeier, BL | 1 |
| Brown, AW | 1 |
| Welch, KD | 1 |
| Shaw, D | 1 |
| Liang, Q | 1 |
| Ni, C | 1 |
| Yan, X | 1 |
| Xie, M | 1 |
| Zhang, Y | 2 |
| Zhang, Q | 1 |
| Yang, M | 1 |
| Peng, S | 1 |
3 reviews available for aristolochic acid i and Adverse Drug Event
| Article | Year |
|---|---|
[Advance in studies on toxicity of aristolochic acid and analysis on risk factors].
Topics: Animals; Aristolochia; Aristolochic Acids; Drug Therapy; Drug-Related Side Effects and Adverse React | 2014 |
Safety concerns of herbal products and traditional Chinese herbal medicines: dehydropyrrolizidine alkaloids and aristolochic acid.
Topics: Aristolochic Acids; Consumer Product Safety; Drug Contamination; Drug-Related Side Effects and Adver | 2015 |
Toxicological risks of Chinese herbs.
Topics: Aconitum; Adverse Drug Reaction Reporting Systems; Aristolochia; China; Drug Contamination; Drug-Rel | 2010 |
2 other studies available for aristolochic acid i and Adverse Drug Event
| Article | Year |
|---|---|
[Risk assessment, safe medication and scientific supervision of traditional Chinese medicine containing aristolochic acids--toxicity is different among aristolochic acids, and detection and control of aristolochic acid Ⅰ/Ⅱ is critical].
Topics: Aristolochia; Aristolochic Acids; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese He | 2022 |
[Comparative study on metabonomics and on liver and kidney toxicity of Aristolochia fangchi and Stephania tetrandra].
Topics: Animals; Aristolochia; Blood Chemical Analysis; Drug-Related Side Effects and Adverse Reactions; Dru | 2010 |