aristolochic acid i has been researched along with Adenoma, Oxyphilic in 1 studies
aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.
Adenoma, Oxyphilic: A usually benign glandular tumor composed of oxyphil cells, large cells with small irregular nuclei and dense acidophilic granules due to the presence of abundant MITOCHONDRIA. Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askanazy cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These results differ from previous reports in that tumours originating from both epithelial and mesenchymal tissues were found, which may be attributed to the duration of treatment and the dosage of the drug." | 1.33 | Tumour induction in rats following exposure to short-term high dose aristolochic acid I. ( Cui, M; Li, H; Li, LS; Liu, ZH; Qiu, Q, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, M | 1 |
| Liu, ZH | 1 |
| Qiu, Q | 1 |
| Li, H | 1 |
| Li, LS | 1 |
1 other study available for aristolochic acid i and Adenoma, Oxyphilic
| Article | Year |
|---|---|
Tumour induction in rats following exposure to short-term high dose aristolochic acid I.
Topics: Adenoma, Oxyphilic; Animals; Aristolochic Acids; Carcinogens; Female; Kidney; Kidney Neoplasms; Rats | 2005 |