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aristolochic acid i and Abnormalities, Drug-Induced

aristolochic acid i has been researched along with Abnormalities, Drug-Induced in 1 studies

aristolochic acid I: phospholipase A inhibitor
aristolochic acid A : An aristolochic acid that is phenanthrene-1-carboxylic acid that is substituted by a methylenedioxy group at the 3,4 positions, by a methoxy group at position 8, and by a nitro group at position 10. It is the most abundant of the aristolochic acids and is found in almost all Aristolochia (birthworts or pipevines) species. It has been tried in a number of treatments for inflammatory disorders, mainly in Chinese and folk medicine. However, there is concern over their use as aristolochic acid is both carcinogenic and nephrotoxic.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ding, YJ1
Chen, YH1

Other Studies

1 other study available for aristolochic acid i and Abnormalities, Drug-Induced

ArticleYear
Developmental nephrotoxicity of aristolochic acid in a zebrafish model.
    Toxicology and applied pharmacology, 2012, May-15, Volume: 261, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Aristolochic Acids; Dose-Response Relationship, Drug; Embryo,

2012