Page last updated: 2024-09-05

arimoclomol and Disease Models, Animal

arimoclomol has been researched along with Disease Models, Animal in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aguila, M; Athanasiou, D; Bevilacqua, D; Cheetham, ME; Coffey, PJ; Greensmith, L; Kalmar, B; Kanuga, N; McCulley, CH; Mendes, HF; Munro, PM; Novoselov, SS; Parfitt, DA1
Arenz, C; Atkins, J; Begley, D; Bornæs, C; Drndarski, S; Gray, J; Hinsby, A; Ingemann, L; Jäättelä, M; Jørgensen, SH; Kirkegaard, T; Klein, A; Morris, L; Olsen, OD; Petersen, NH; Platt, FM; Priestman, DA; Smith, DA; Wallom, KL; Williams, I1
Cheetham, ME; Gray, A; Greensmith, L; Kalmar, B; Margulis, B; Novoselov, S1
Edet-Amana, E; Greensmith, L; Kalmar, B1
Dick, J; Greensmith, L; Kalmar, B; Lu, CH; Malaspina, A; Petzold, A1
Gray, AL; Greensmith, L; Hanna, MG; La Spada, AR; Malik, B; Nirmalananthan, N1
Benn, SC; Brown, RH1

Other Studies

7 other study(ies) available for arimoclomol and Disease Models, Animal

ArticleYear
The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa.
    Cell death & disease, 2014, May-22, Volume: 5

    Topics: Animals; Cell Line; Cell Survival; Cytoprotection; Disease Models, Animal; Dose-Response Relationship, Drug; Electroretinography; Heat-Shock Response; Humans; Hydroxylamines; Mutation; Photoreceptor Cells, Vertebrate; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Retinal Degeneration; Retinitis Pigmentosa; Rhodopsin; Time Factors; Transfection; Unfolded Protein Response; Vision, Ocular

2014
Heat shock protein-based therapy as a potential candidate for treating the sphingolipidoses.
    Science translational medicine, 2016, 09-07, Volume: 8, Issue:355

    Topics: Administration, Intravenous; Animals; Blood-Brain Barrier; Bone Morphogenetic Proteins; Disease Models, Animal; Disease Progression; Fabry Disease; Fibroblasts; Glycosphingolipids; Heat-Shock Proteins; Humans; Hydroxylamines; Injections, Intraperitoneal; Intracellular Signaling Peptides and Proteins; Lysosomes; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Proteins; Recombinant Proteins; Sphingolipidoses; Tissue Distribution

2016
Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS.
    Journal of neurochemistry, 2008, Volume: 107, Issue:2

    Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Disease Progression; Female; HSP70 Heat-Shock Proteins; Humans; Hydroxylamines; Male; Mice; Mice, Transgenic; Motor Neurons; Muscle, Skeletal; Spinal Cord; Statistics, Nonparametric; Superoxide Dismutase; Survival Analysis; Ubiquitin

2008
Treatment with a coinducer of the heat shock response delays muscle denervation in the SOD1-G93A mouse model of amyotrophic lateral sclerosis.
    Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2012, Volume: 13, Issue:4

    Topics: Acetylcholinesterase; Amyotrophic Lateral Sclerosis; Animals; Choline O-Acetyltransferase; Disease Models, Animal; Disease Progression; GPI-Linked Proteins; Heat-Shock Response; HSP70 Heat-Shock Proteins; Hydroxylamines; Longitudinal Studies; Mice; Mice, Transgenic; Motor Neurons; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Neuromuscular Junction; Succinate Dehydrogenase; Superoxide Dismutase

2012
Plasma neurofilament heavy chain levels correlate to markers of late stage disease progression and treatment response in SOD1(G93A) mice that model ALS.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Amyotrophic Lateral Sclerosis; Animals; Biomarkers; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Female; Hydroxylamines; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscles; Neurofilament Proteins; Phosphorylation; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Treatment Outcome

2012
Co-induction of the heat shock response ameliorates disease progression in a mouse model of human spinal and bulbar muscular atrophy: implications for therapy.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 3

    Topics: Animals; Blotting, Western; Disease Models, Animal; Disease Progression; Heat-Shock Proteins; Heat-Shock Response; Hydroxylamines; Male; Mice; Muscular Disorders, Atrophic; Neuroprotective Agents; Real-Time Polymerase Chain Reaction

2013
Putting the heat on ALS.
    Nature medicine, 2004, Volume: 10, Issue:4

    Topics: Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Heat-Shock Response; Hydroxylamines; Life Expectancy; Mice; Superoxide Dismutase

2004