arginyl-glycyl-aspartic acid has been researched along with Ovarian Neoplasms in 43 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (9.30) | 18.2507 |
2000's | 24 (55.81) | 29.6817 |
2010's | 14 (32.56) | 24.3611 |
2020's | 1 (2.33) | 2.80 |
Authors | Studies |
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Feng, W; Tang, Z; Wang, Q; Yang, Y | 1 |
Guo, L; Long, Q; Pu, L; Zhu, W | 1 |
Chen, H; Li, J; Li, X; Luo, J; Niu, W; Tang, J; Tong, L; Wang, J; Wang, Y; Xiao, Q; Zhong, L; Zhu, J | 1 |
Buckway, B; Cheney, DL; Ghandehari, H; Larson, N; Ray, A; Roberts, S | 1 |
Ashur-Fabian, O; Baraf, L; Cohen, K; Davis, PJ; Ellis, M; Hercbergs, A; Nabriski, D; Shinderman-Maman, E; Twito, O; Weingarten, C; Werner, H | 1 |
Lin, Z; Wu, J; Yao, D | 1 |
Chen, G; Gong, S; Wang, L; Wang, Y | 1 |
Gou, M; Han, J; Jiang, Q; Li, B; Li, Q; Wang, J; Xiao, R; Zheng, Y | 1 |
Gao, JQ; Han, M; Hatanaka, Y; Kanagawa, N; Mayumi, T; Mizuguchi, H; Nakagawa, S; Okada, N; Tani, Y; Tsuda, Y; Tsutsumi, Y; Xu, DH | 1 |
Luo, CL; Sun, QS; Wang, JC; Zhang, Q; Zhao, H | 1 |
Cai, W; Cao, F; Chen, K; Chen, X; Lee, A; Li, Z; Liu, Z; Wang, H; Wu, JC | 1 |
Ballmer-Hofer, K; Cohrs, S; Fischer, E; Friedli, A; Grünberg, J; Novak-Hofer, I; Schibli, R; Schubiger, PA | 1 |
Addadi, Y; Eisenhut, M; Huppert, J; Jayapaul, J; Kiessling, F; Mueller, MM; Neeman, M; Semmler, W; Woenne, EC; Zentgraf, H; Zhang, C; Zwick, S | 1 |
Aulicino, C; Bargiotti, A; Bucci, F; Castorina, M; Dal Pozzo, A; Dallavalle, S; Esposito, E; Foderà, R; Giannini, G; Musso, L; Ni, MH; Penco, S; Pisano, C; Vesci, L | 1 |
Han, HD; Kim, HS; Lee, JW; Lee, SJ; Lopez-Berestein, G; Lu, C; Mangala, LS; Mora, EM; Nam, EJ; Nick, AM; Roh, JW; Shahzad, MM; Shen, D; Sood, AK; Stone, RL | 1 |
Clements, JA; Hutmacher, DW; Loessner, D; Lutolf, MP; Rizzi, SC; Stok, KS | 1 |
Kim, Y; Morris, DL; Pourgholami, MH; Stenzel, MH | 1 |
Liu, Y; Wei, Y; Yin, X; Zhang, B; Zhang, P; Zheng, J | 1 |
Brenton, JD; Temple, J; Tumbarello, DA | 1 |
Alloatti, D; Badaloni, E; Cabri, W; Castorina, M; Giannini, G; Pisano, C; Vesci, L | 1 |
Boerman, OC; Boonstra, H; Corstens, FH; Dijkgraaf, I; Edwards, DS; Frielink, C; Janssen, ML; Massuger, LF; Oyen, WJ; Rajopadhye, M | 1 |
Boerman, OC; Corstens, FH; Dijkgraaf, I; Edwards, DS; Frielink, C; Janssen, M; Massuger, LF; Oyen, WJ; Radjopadhye, M | 1 |
Alvarez, RD; Barker, SD; Barnes, MN; Bauerschmitz, GJ; Blackwell, JL; Curiel, DT; Hemminki, A; Kanerva, A; Lam, JT; Siegal, GP; Straughn, JM; Wang, M | 1 |
Bartlett, JS; Shi, W | 1 |
Alvarez, RD; Barnes, MN; Curiel, DT; Dmitriev, I; Han, T; Kashentseva, E; Lam, JT; Leath, CA; Wu, H | 1 |
Ramakrishnan, S; Yokoyama, Y | 1 |
Boerman, O; Corstens, F; Dijkgraaf, I; Edwards, DS; Frielink, C; Janssen, M; Liu, S; Massuger, L; Oyen, W; Rajopadhye, M | 1 |
Beck, V; Benge, A; Geppert, HG; Herold, H; Hutzler, P; Kessler, H; Luber, B; Reuning, U; Schmitt, M; Tschesche, H | 1 |
Alvarez, RD; Barnes, MN; Curiel, DT; Dmitriev, I; Hemminki, A; Krasnykh, V; Liu, B; Siegal, GP; Wang, M | 1 |
Boturyn, D; Coll, JL; Dumy, P; Favrot, MC; Garanger, E; Jin, Z | 1 |
Alvarez, RD; Carey, D; Chada, S; Curiel, DT; Dent, P; Fisher, PB; Haisma, HJ; Kataram, M; Mahasreshti, PJ; Wu, H; Yalavarthy, LP | 1 |
Boerman, OC; Corstens, FH; Dijkgraaf, I; Frielink, C; Kruijtzer, JA; Liskamp, RM; Oyen, WJ | 1 |
Alvarez, RD; Curiel, DT; Lu, B; Makhija, SK; Rivera, AA; Rocconi, RP; Stoff-Khalili, M; Wang, M; Zhu, ZB | 1 |
Alvarez, RD; Aurigemma, R; Broadt, T; Curiel, DT; Harris, R; Makhija, S; Noker, PE; Page, JG; Polley-Nelson, J; Schweikart, K; Tian, B; Tomaszewski, J; Wang, M | 1 |
Akiyama, M; Einfeld, DA; King, CR; Murugesan, SR; Wickham, TJ | 1 |
Gao, JQ; Han, M; Hatanaka, Y; Kanagawa, N; Mayumi, T; Mizuguchi, H; Nakagawa, S; Okada, N; Sugita, T; Tani, Y; Tsutsumi, Y; Xu, DH | 1 |
Amano, R; Kawai, K; Mori, H; Ogawa, K; Shikano, N; Washiyama, K; Yoshimoto, M | 1 |
Cannistra, SA; DiCarlo, J; Niloff, J; Orta, B; Ottensmeier, C | 1 |
Belousova, N; Curiel, DT; Dmitriev, I; Kashentseva, E; Krasnykh, V; Mikheeva, G; Miller, CR; Wang, M | 1 |
Alvarez, R; Barnes, M; Curiel, DT; Dmitriev, I; Gómez-Navarro, J; Krasnykh, V; Rancourt, C; Siegal, GP; Vanderkwaak, TJ; Wang, M | 1 |
Bar-Shavit, R; Even-Ram, SC; Maoz, M; Meir, G; Neeman, M; Schiffenbauer, YS | 1 |
Alemany, R; Alvarez, RD; Barnes, MN; Bauerschmitz, GJ; Curiel, DT; Dall, P; Dmitriev, I; Hemminki, A; Kanerva, A; Krasnykh, V; Lam, JT; Mikheeva, GV; Nettelbeck, DM; Suzuki, K | 1 |
Murae, M; Yamamoto, K; Yasuda, M | 1 |
43 other study(ies) available for arginyl-glycyl-aspartic acid and Ovarian Neoplasms
Article | Year |
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Gemcitabine-loaded RGD modified liposome for ovarian cancer: preparation, characterization and pharmacodynamic studies.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; China; Deoxycytidine; Drug Delivery Systems; Drug Liberation; Female; Gemcitabine; Humans; Liposomes; Mice; Mice, Inbred BALB C; Nanoparticles; Oligopeptides; Ovarian Neoplasms; Particle Size; Rats | 2019 |
RGD-Conjugated Resveratrol HSA Nanoparticles as a Novel Delivery System in Ovarian Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms, Experimental; Oligopeptides; Ovarian Neoplasms; Resveratrol; Serum Albumin, Human | 2020 |
cRGD-functionalized nanoparticles for combination therapy of anti-endothelium dependent vessels and anti-vasculogenic mimicry to inhibit the proliferation of ovarian cancer.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Chick Embryo; Endothelium, Vascular; Female; Folic Acid; Heparin; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Ovarian Neoplasms; Xenograft Model Antitumor Assays | 2019 |
In vitro synergistic action of geldanamycin- and docetaxel-containing HPMA copolymer-RGDfK conjugates against ovarian cancer.
Topics: Antibiotics, Antineoplastic; Benzoquinones; Cell Death; Cell Line, Tumor; Docetaxel; Drug Screening Assays, Antitumor; Female; Humans; Integrin alphaVbeta3; Lactams, Macrocyclic; Methacrylates; Oligopeptides; Ovarian Neoplasms; Taxoids | 2014 |
The thyroid hormone-αvβ3 integrin axis in ovarian cancer: regulation of gene transcription and MAPK-dependent proliferation.
Topics: Antibodies, Neutralizing; Cell Division; Cell Line, Tumor; Culture Media; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; Hypothyroidism; Integrin alphaV; Integrin alphaVbeta3; Integrin beta3; MAP Kinase Signaling System; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Oligopeptides; Ovarian Neoplasms; Phosphorylation; Protein Processing, Post-Translational; RNA, Messenger; RNA, Neoplasm; Thyroxine; Transcription, Genetic; Triiodothyronine | 2016 |
Near-Infrared Fluorogenic Probes with Polarity-Sensitive Emission for in Vivo Imaging of an Ovarian Cancer Biomarker.
Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescent Dyes; Humans; Integrin alphaVbeta3; Lysophospholipids; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Oligopeptides; Ovarian Neoplasms; Spectroscopy, Near-Infrared; Transplantation, Heterologous | 2016 |
Carboplatin-Complexed and cRGD-Conjugated Unimolecular Nanoparticles for Targeted Ovarian Cancer Therapy.
Topics: Antineoplastic Agents; Carboplatin; Female; Flow Cytometry; Humans; Microscopy, Confocal; Nanoparticles; Oligopeptides; Ovarian Neoplasms; Polymers | 2017 |
rLj-RGD3 induces apoptosis via the mitochondrial-dependent pathway and inhibits adhesion, migration and invasion of human HeyA8 cells via FAK pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Movement; Cell Proliferation; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Female; Focal Adhesion Kinase 1; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitochondria; Neoplasm Invasiveness; Oligopeptides; Ovarian Neoplasms; Phosphorylation; Recombinant Proteins | 2017 |
NK cells are migrated and indispensable in the anti-tumor activity induced by CCL27 gene therapy.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Chemokine CCL27; Female; Genetic Therapy; Genetic Vectors; Humans; Injections, Intralesional; Interleukin-12; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Oligopeptides; Ovarian Neoplasms | 2009 |
RGD-based strategies for improving antitumor activity of paclitaxel-loaded liposomes in nude mice xenografted with human ovarian cancer.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Body Weight; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Fluorescence; Humans; Inhibitory Concentration 50; Injections, Intravenous; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oligopeptides; Ovarian Neoplasms; Paclitaxel; Xenograft Model Antitumor Assays | 2009 |
Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Copper Radioisotopes; Embryonic Stem Cells; Endothelial Cells; Female; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Organometallic Compounds; Ovarian Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Teratoma; Transplantation, Heterologous | 2009 |
The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor.
Topics: Angiogenic Proteins; Animals; Antibodies, Monoclonal; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chickens; Chorioallantoic Membrane; Collagen; Drug Combinations; Endothelial Cells; Female; Fibronectins; Humans; Laminin; Neoplasms; Neovascularization, Pathologic; Neural Cell Adhesion Molecule L1; Oligopeptides; Ovarian Neoplasms; Protein Structure, Tertiary; Proteoglycans; Repetitive Sequences, Amino Acid; Solubility; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
RGD-labeled USPIO inhibits adhesion and endocytotic activity of alpha v beta3-integrin-expressing glioma cells and only accumulates in the vascular tumor compartment.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Survival; Cells, Cultured; Contrast Media; Dextrans; Endocytosis; Endothelium, Vascular; Female; Ferrosoferric Oxide; Fluorescent Antibody Technique; Glioblastoma; Glioma; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Nude; Neoplasm Transplantation; Oligopeptides; Ovarian Neoplasms; Umbilical Veins | 2009 |
Novel tumor-targeted RGD peptide-camptothecin conjugates: synthesis and biological evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carcinoma; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Female; Humans; Mice; Mice, Nude; Molecular Structure; Oligopeptides; Ovarian Neoplasms | 2010 |
Targeted gene silencing using RGD-labeled chitosan nanoparticles.
Topics: Animals; Antineoplastic Agents; Blotting, Western; Chitosan; Drug Delivery Systems; Female; Gene Silencing; Genetic Therapy; Humans; Mice; Mice, Nude; Nanoparticles; Neoplasm Proteins; Oligopeptides; Ovarian Neoplasms; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2010 |
Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Bioengineering; Biomimetic Materials; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Epithelial Cells; Female; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Integrins; Mechanical Phenomena; Oligopeptides; Ovarian Neoplasms; Paclitaxel; Polyethylene Glycols; Spheroids, Cellular | 2010 |
An optimized RGD-decorated micellar drug delivery system for albendazole for the treatment of ovarian cancer: from RAFT polymer synthesis to cellular uptake.
Topics: Albendazole; Cell Death; Cell Line, Tumor; Cell Survival; Chromatography, Gel; Drug Delivery Systems; Female; Humans; Hydrodynamics; Micelles; Microscopy, Fluorescence; Molecular Weight; Oligopeptides; Ovarian Neoplasms; Polymerization; Polymers; Polymethacrylic Acids; Solubility; Surface Tension | 2011 |
A novel CRAd in combination with cisplatin enhanced the antitumor efficacy in ovarian cancer.
Topics: Adenoviruses, Human; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cisplatin; Combined Modality Therapy; Female; Humans; Inhibitor of Apoptosis Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Oncolytic Virotherapy; Ovarian Neoplasms; Random Allocation; Survivin; Virus Replication; Xenograft Model Antitumor Assays | 2011 |
ß3 integrin modulates transforming growth factor beta induced (TGFBI) function and paclitaxel response in ovarian cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Cell Adhesion; Cell Adhesion Molecules; Cell Death; Cell Line, Tumor; Extracellular Matrix; Extracellular Matrix Proteins; Female; Gene Expression Regulation, Neoplastic; Humans; Integrin beta3; Oligopeptides; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Interaction Domains and Motifs; Protein Subunits; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Signal Transduction; Syndecan-1; Transforming Growth Factor beta | 2012 |
Camptothecins in tumor homing via an RGD sequence mimetic.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Female; Humans; Integrins; Male; Oligopeptides; Ovarian Neoplasms; Prostatic Neoplasms; Rats | 2012 |
Tumor targeting with radiolabeled alpha(v)beta(3) integrin binding peptides in a nude mouse model.
Topics: Animals; Female; Humans; Indium Radioisotopes; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Ovarian Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Substrate Specificity; Technetium; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Yttrium Radioisotopes | 2002 |
Comparison of a monomeric and dimeric radiolabeled RGD-peptide for tumor targeting.
Topics: Animals; Dimerization; Female; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Oligopeptides; Ovarian Neoplasms; Technetium; Tissue Distribution; Tumor Cells, Cultured | 2002 |
Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids.
Topics: Adenoviridae; Ascites; Female; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrins; Oligopeptides; Ovarian Neoplasms; Spheroids, Cellular; Tumor Cells, Cultured; Virus Replication | 2003 |
RGD inclusion in VP3 provides adeno-associated virus type 2 (AAV2)-based vectors with a heparan sulfate-independent cell entry mechanism.
Topics: Animals; Biological Transport; Capsid Proteins; Cell Culture Techniques; Dependovirus; Epitopes; Female; Genetic Vectors; HeLa Cells; Heparin; Humans; Integrins; K562 Cells; Mice; Mice, SCID; Oligopeptides; Ovarian Neoplasms; Proteoglycans; Tumor Cells, Cultured; Virion | 2003 |
Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy.
Topics: Adenoviridae; Animals; Disease Models, Animal; Female; Gene Targeting; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Oligopeptides; Ovarian Neoplasms; Polylysine; Tumor Cells, Cultured | 2004 |
Addition of integrin binding sequence to a mutant human endostatin improves inhibition of tumor growth.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Endostatins; Female; Half-Life; Humans; Integrins; Ligands; Mice; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Ovarian Neoplasms | 2004 |
Improved tumor targeting of radiolabeled RGD peptides using rapid dose fractionation.
Topics: Animals; Dose Fractionation, Radiation; Female; Humans; Indium Radioisotopes; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Ovarian Neoplasms; Radiopharmaceuticals; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes | 2004 |
ADAM15 decreases integrin alphavbeta3/vitronectin-mediated ovarian cancer cell adhesion and motility in an RGD-dependent fashion.
Topics: ADAM Proteins; Animals; Cell Adhesion; Cell Line, Tumor; Cell Movement; CHO Cells; Cricetinae; Cricetulus; Female; Humans; Immunohistochemistry; Integrin alphaVbeta3; Kinetics; Membrane Proteins; Metalloendopeptidases; Microscopy, Confocal; Oligopeptides; Ovarian Neoplasms; Vitronectin | 2005 |
Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.
Topics: Adenoviridae; Animals; Antibodies; Antibody Formation; Capsid Proteins; Female; Gene Transfer Techniques; Humans; Luciferases; Mice; Mice, Inbred BALB C; Oligopeptides; Ovarian Neoplasms | 2005 |
New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors.
Topics: Animals; Binding, Competitive; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Separation; Dose-Response Relationship, Drug; Endosomes; Female; Flow Cytometry; Genetic Therapy; Genetic Vectors; Humans; Immunohistochemistry; Infusions, Intravenous; Integrin alphaVbeta3; Ligands; Mice; Mice, Nude; Models, Chemical; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Oligopeptides; Ovarian Neoplasms; Peptides; Peptides, Cyclic; Polymers; Stereoisomerism; Vitronectin | 2005 |
Ovarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy.
Topics: Adenocarcinoma; Adenoviridae; Animals; Cell Line, Tumor; Female; Genetic Therapy; Genetic Vectors; Humans; Interleukins; Mice; Mice, SCID; Oligopeptides; Ovarian Neoplasms; Polymerase Chain Reaction; Xenograft Model Antitumor Assays | 2006 |
Alpha v beta 3 integrin-targeting of intraperitoneally growing tumors with a radiolabeled RGD peptide.
Topics: Animals; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Injections, Intraperitoneal; Injections, Intravenous; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Ovarian Neoplasms; Peritoneal Neoplasms; Radiopharmaceuticals; Survival Analysis; Tissue Distribution; Xenograft Model Antitumor Assays | 2007 |
Treatment of ovarian cancer with a novel dual targeted conditionally replicative adenovirus (CRAd).
Topics: Adenoviruses, Human; Capsid; Cell Line, Tumor; Female; Humans; Liver; Oligopeptides; Oncolytic Virotherapy; Ovarian Neoplasms; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; Virus Replication | 2007 |
Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer.
Topics: Adenoviridae; Analysis of Variance; Animals; Disease Models, Animal; Female; Gene Transfer Techniques; Genetic Vectors; Injections, Intraperitoneal; Injections, Intravenous; Neoplasm Recurrence, Local; Oligopeptides; Oncolytic Virotherapy; Ovarian Neoplasms; Polymerase Chain Reaction; Probability; Random Allocation; Rats; Rats, Inbred Strains; Reference Values; Sensitivity and Specificity; Sigmodontinae; Survival Analysis | 2007 |
Experimental treatment of ovarian cancers by adenovirus vectors combining receptor targeting and selective expression of tumor necrosis factor.
Topics: Adenoviridae; Animals; Capsid; Female; Gene Targeting; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrin alphaVbeta3; Luciferases; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, SCID; Oligopeptides; Ovarian Neoplasms; Peritoneal Neoplasms; Promoter Regions, Genetic; Survival Rate; Transduction, Genetic; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2007 |
Combination of two fiber-mutant adenovirus vectors, one encoding the chemokine FKN and another encoding cytokine interleukin 12, elicits notably enhanced anti-tumor responses.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Drug Therapy, Combination; Female; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Interferon-gamma; Interleukin-11 Receptor alpha Subunit; Interleukin-12; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Oligopeptides; Ovarian Neoplasms | 2008 |
alpha(v)beta(3) Integrin-targeting radionuclide therapy and imaging with monomeric RGD peptide.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 1-Ring; Humans; Indium Radioisotopes; Integrin alphaVbeta3; Isotope Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Ovarian Neoplasms; Protein Conformation; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution; Xenograft Model Antitumor Assays; Yttrium Radioisotopes | 2008 |
Expression and function of beta 1 and alpha v beta 3 integrins in ovarian cancer.
Topics: Amino Acid Sequence; Cell Adhesion; Collagen; Epithelial Cells; Epithelium; Extracellular Matrix; Female; Fibronectins; Humans; Immunohistochemistry; Integrin beta1; Integrins; Laminin; Molecular Sequence Data; Oligopeptides; Ovarian Neoplasms; Peritoneal Cavity; Receptors, Cytoadhesin; Receptors, Fibronectin; Receptors, Vitronectin; RNA, Messenger; Tumor Cells, Cultured | 1995 |
An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism.
Topics: Adenoviruses, Human; Base Sequence; Capsid; Capsid Proteins; Cell Line; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Enterovirus; Female; Genetic Therapy; Genetic Vectors; Humans; Molecular Sequence Data; Oligopeptides; Ovarian Neoplasms; Plasmids; Receptors, Virus; Recombination, Genetic; Tumor Cells, Cultured | 1998 |
An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.
Topics: Adenoviridae; Amino Acid Sequence; Female; Gene Transfer Techniques; Genetic Vectors; Humans; Luciferases; Oligopeptides; Ovarian Neoplasms; Tumor Cells, Cultured | 1999 |
Gonadotropin stimulation of MLS human epithelial ovarian carcinoma cells augments cell adhesion mediated by CD44 and by alpha(v)-integrin.
Topics: Antigens, CD; Blotting, Western; Cell Adhesion; Epithelial Cells; Female; Follicle Stimulating Hormone; Humans; Hyaluronan Receptors; Hyaluronic Acid; Integrin alphaV; Luteinizing Hormone; Oligopeptides; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 2002 |
Treatment of ovarian cancer with a tropism modified oncolytic adenovirus.
Topics: Adenoviridae; Animals; Female; Genetic Therapy; Mice; Mice, SCID; Oligopeptides; Ovarian Neoplasms; Spheroids, Cellular; Virus Replication | 2002 |
RGD-containing peptides inhibit experimental peritoneal seeding of human ovarian cancer cells.
Topics: Animals; Cell Adhesion; Extracellular Matrix; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oligopeptides; Ovarian Neoplasms; Peritoneal Neoplasms; Tumor Cells, Cultured | 1991 |