arginyl-glycyl-aspartic acid has been researched along with Neoplasms in 243 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (2.88) | 18.2507 |
| 2000's | 62 (25.51) | 29.6817 |
| 2010's | 152 (62.55) | 24.3611 |
| 2020's | 22 (9.05) | 2.80 |
| Authors | Studies |
|---|---|
| Kesharwani, P; Md, S; Sheikh, A | 1 |
| Chen, X; Han, Z; Hua, Y; Kang, X; Liu, JQ; Wang, Y; Wang, ZY; Xu, F; Zang, SQ; Zhang, C; Zhao, X | 1 |
| Jiang, T; Li, A; Liu, W; Ouyang, A; Wang, X; Zhang, W; Zhao, D | 1 |
| Ali, MK; Bian, X; Chen, X; Kong, Q; Li, M; Liang, K; Tian, Z; Zhang, X | 1 |
| Ahmadi, Z; Jha, D; Kumar Gautam, H; Kumar Sharma, A; Kumar, P | 1 |
| Mohri, K; Mukai, H; Nhat, KPH; Tagami, S; Wada, Y; Warashina, S; Watanabe, Y; Zouda, M | 1 |
| Chen, G; Dai, J; Huang, B; Li, Y; Liu, J; Nie, J; Ren, L; Yin, J | 1 |
| Ematsu, Y; Fuchigami, T; Hirose, K; Imai, S; Kinuya, S; Mishiro, K; Munekane, M; Ogawa, K | 1 |
| Demin, AM; Gruzdev, DA; Krasnov, VP; Levit, GL; Vakhrushev, AV | 1 |
| Alt, K; Björnmalm, M; Braunger, JA; Caruso, F; Cui, J; Dai, Q; Dai, Y; Gunawan, ST; Guo, J; Hagemeyer, CE; Ju, Y; Richardson, JJ; Wang, TY | 1 |
| Bañobre, M; Belderbos, S; Danhier, P; de Cuyper, M; Gallez, B; Gallo, J; Garcia Ribeiro, RS; Gsell, W; Himmelreich, U; Manshian, BB; Soenen, SJ | 1 |
| Bai, YJ; Gong, YK; Li, N; Li, T; Ma, Y; Xing, CM | 1 |
| Bao, W; Chen, H; Chen, Q; Chen, S; Liu, T; Luo, Y; Ma, M; Xue, F; Zhang, L | 1 |
| Ge, Y; O'Shea, DF | 1 |
| Chernyavska, M; Freitag, PC; Huck, WTS; Palacio-Castañeda, V; Piruska, A; Plückthun, A; Schmid, M; Verdurmen, WPR | 1 |
| Akrami, M; Alipour, M; Baneshi, M; Bardania, H; Hosseinkhani, S; Jabari Arabzadeh, A; Mahmoudi, R; Mehrzad, J | 1 |
| Farahani, AM; Maleki, F; Sadeghzadeh, N | 1 |
| Agut, M; Boix-Garriga, E; Boyle, RW; Bryden, F; de Las Heras, E; Lange, N; Mora, M; Nonell, S; Sagristá, ML | 1 |
| Chen, S; Gu, YT; Liu, F; Pan, BQ; Wang, YF; Yan, GP; Yan, JR; Zhang, Q | 1 |
| Chen, W; Dong, C; Guo, X; Li, F; Song, C; Wang, L; Zhang, J | 1 |
| Lv, X; Shuaizhen, Q; Yu, R; Zhang, C; Zheng, Y | 1 |
| Farokhzad, OC; Hanyu, M; Hu, K; Ji, X; Liang, SH; Nagatsu, K; Ouyang, J; Suzuki, H; Tao, W; Wang, L; Wei, J; Xie, L; Xu, H; Yang, Z; Zhang, MR; Zhang, Y | 1 |
| Hao, X; Liu, J; Qiu, K; Wang, J; Zhao, Z | 1 |
| Bruban, V; Choulier, L; Dontenwill, M; Entz-Werle, N; Etienne-Selloum, N; Fuchs, Q; Laquerriere, P; Martin, S; Messe, M; Pierrevelcin, M; Reita, D; Sani, S | 1 |
| Deli, MA; Dér, A; Horvath, R; Kanyo, N; Kovacs, KD; Peter, B; Saftics, A; Santa-Maria, AR; Szekacs, I; Walter, FR | 1 |
| Bai, J; Cao, J; Gao, Z; Gong, Z; Guan, X; Hong, Z; Liu, X; Lu, H; Pan, X; Sun, X; Wang, G; Xu, Y; Zhang, J; Zhou, B | 1 |
| Bauwens, M; Florea, A; Mottaghy, FM | 1 |
| Hu, D; Li, K; Li, Y; Li, Z; Lu, SB; Sheng, Z; Wang, S; Zha, M | 1 |
| Echigo, H; Hirata, S; Kinuya, S; Kitamura, Y; Mishiro, K; Ogawa, K; Shiba, K; Takahashi, K; Washiyama, K | 1 |
| Wang, H; Xu, J; Yang, J; Yin, H; Zhang, Q; Zheng, J | 1 |
| Bao, Y; Guo, Y; Huang, Z; Li, Y; Wu, F; Xu, H; Xu, P; Yan, X | 1 |
| Abbasi, MM; Adli, ADF; Behzadi, R; Farajnia, S; Farajzadeh, D; Jahanban-Esfahlan, R; Javaheri, T; Minofar, B; Monhemi, H; Seidi, K; Zare, P; Zarghami, N | 1 |
| Du, L; Hu, Y; Li, X; Shen, M; Shi, X; Wang, R; Xing, L; Xiong, Z; Xu, X | 1 |
| Jin, X; Liang, G; Xing, D; Zhang, S | 1 |
| Sun, Y; Teng, Z; Wang, L; Weng, L; Xiu, W; Yuwen, L; Zhang, Q; Zhang, Y; Zhu, D | 1 |
| Chatzisideri, T; Dalezis, P; Katsamakas, S; Sarli, V; Thysiadis, S; Trafalis, D | 1 |
| Chen, M; Chen, X; Guo, Z; Tian, H; Xu, M; Zhou, X | 1 |
| Harashima, H; Sakurai, Y; Yamamoto, S | 1 |
| Bharathiraja, S; Bui, NQ; Kim, H; Lee, KD; Manivasagan, P; Mondal, S; Moorthy, MS; Oh, J; Phuoc, NT; Seo, H; Vy Phan, TT | 1 |
| Cao, QR; Chen, LQ; Cui, JH; Huang, HY; Jin, H; Lee, BJ; Li, B; Liu, Y; Zhang, XX | 1 |
| Fu, S; Ma, Y; Xu, X; Zhang, S | 1 |
| Bartolomé, RA; Casal, JI | 1 |
| Chen, X; Chen, Y; Hu, C; Huang, Y | 1 |
| Li, F; Mao, C; Ming, X; Zhao, Y | 1 |
| Carvalho, SM; Cunha, ADS; Leite, MF; Lobato, ZIP; Mansur, AAP; Mansur, HS | 1 |
| Chen, F; Chen, H; Ding, N; Ji, L; Liu, B; Meng, F; Qian, H; Sha, H; Xu, Q; Yu, L; Zhang, L; Zhou, Y; Zhu, A | 1 |
| Flores-Holguín, N; Glossman-Mitnik, D; Landeros-Martínez, LL | 1 |
| Cheng, Y; Ji, Y | 1 |
| Hu, M; Sun, Y; Xu, C; Yang, C; Yu, Y; Zhang, Z | 1 |
| Fu, Z; Guo, B; Hu, Q; Huang, Z; Liu, B; Middha, E; Wang, Z | 1 |
| Guo, J; Jiang, L; Min, Q; Wu, R; Zheng, T; Zhu, JJ | 1 |
| Cherukula, K; Park, IK; Uthaman, S | 1 |
| Han, G; Huang, K; Iris, A; Li, J; Ma, B; Mei, L; Qiu, Y; Sun, Y; Xie, J | 1 |
| Cao, S; Du, R; Gao, R; Li, X; Wang, J; Wang, P; Wu, W; Xiang, R; Zhang, C; Zhu, H | 1 |
| Chen, D; Chen, X; Li, H; Li, K; Liang, J; Liu, Y; Xu, X; Zeng, Q; Zeng, Y; Zhan, Y | 1 |
| Backert, S; Buß, M; Dong, X; Li, J; Niemann, HH; Schnieder, J; Springer, TA; Tegtmeyer, N | 1 |
| Cal, S; Cobo, J; Cobo, JL; Cobo, T; Fontanil, T; Mohamedi, Y; Obaya, ÁJ; Pérez-Basterrechea, M; Vega, JA | 1 |
| Arosio, D; Feni, L; Gazzola, S; Neundorf, I; Parente, S; Piarulli, U; Robert, C | 1 |
| Bao, B; Su, P; Tong, L; Wang, L; Weng, L; Xu, Y; Zhai, X; Zhang, J | 1 |
| Harashima, H; Hatakeyama, H; Hida, K; Kibria, G; Ohga, N | 1 |
| Baishya, R; Chatterjee, N; Debnath, MC; Halder, KK; Karmakar, S; Nayak, DK | 1 |
| Baù, L; Boscaini, A; Bovis, M; Colombatti, M; Compagnin, C; Echevarria, IM; Fedeli, C; Fracasso, G; MacKenzie, A; MacRobert, AJ; Mancin, F; Moret, F; Papini, E; Rastrelli, F; Reddi, E; Segat, D; Selvestrel, F; Tavano, R; Woodhams, JH; Yaghini, E; Zanini, S | 1 |
| Li, Y; Shen, Y; Wang, A; Wang, F; Wang, S; Xie, T | 1 |
| Achilefu, S; Chen, H; Cui, S; Dai, S; Gu, Y; Ma, Y; Zhang, X | 1 |
| Barui, S; Chaudhuri, A; Mondal, G; Saha, S | 1 |
| Chen, H; Chuang, YJ; Pan, Z; Tang, W; Todd, T; Wang, L; Xie, J; Zhen, Z | 1 |
| Ke, MR; Lo, PC; Ng, DK | 1 |
| Liu, Z; Wang, F | 1 |
| Chen, X; Eden, HS; Guo, J; Guo, N; Kiesewetter, DO; Lang, L; Li, Q; Niu, G; Xie, Q | 1 |
| Delplace, V; Diou, O; Fattal, E; Mackiewicz, N; Mériaux, S; Nicolas, J; Robic, C; Tsapis, N; Valette, J | 1 |
| Braun, GB; Kotamraju, VR; Pang, HB; Ruoslahti, E; She, ZG; Sugahara, KN; Teesalu, T | 1 |
| Patterson, LH; Sheldrake, HM | 1 |
| An, L; Du, J; Hu, H; Li, F; Shi, H; Wang, L; Wei, J; Wu, D; Yang, H; Yang, S | 1 |
| Cheng, Z; Chin, FT; Gambhir, SS; Jiang, L; Kimura, RH; Ma, X; Miao, Z; Shen, B; Shi, H; Tu, Y | 1 |
| Abe, S; Akasaka, T; Chen, X; Komatsu, N; Watari, F; Xu, YH; Zhao, L | 1 |
| Steinmetz, NF; Wen, AM | 1 |
| Chen, X; Chuang, YJ; Lin, X; Liu, G; Niu, G; Pan, Z; Tang, W; Todd, T; Wang, L; Xie, J; Zhang, W; Zhen, Z | 1 |
| Kim, HA; Kim, SW; Nam, K | 1 |
| Christie, RJ; Fukushima, S; Kataoka, K; Low, SA; Matsumoto, Y; Miura, Y; Miyata, K; Naito, M; Nishiyama, N; Oe, Y; Toh, K | 1 |
| Guan, X; Hu, X; Jing, X; Li, J; Liu, M; Pei, Q; Xie, Z | 1 |
| Jiang, B; Jiang, Y; Liu, C; Liu, Y; Wang, K; Zhang, X | 1 |
| Barnhart, TE; Cai, W; Chakravarty, R; Hernandez, R; Hong, H; Valdovinos, HF; Yang, Y | 1 |
| Chen, X; Hu, H; Huang, P; Jin, A; Li, W; Lin, J; Niu, G; Rong, P; Wang, W; Wang, Z; Yan, X; Yue, X; Zeng, W; Zhang, MG; Zhou, K | 1 |
| Ao, M; Chen, H; Gu, Y; Guo, Y; Li, B; Peng, K; Sun, K; Wang, Y; Zhang, M | 1 |
| Baishya, R; Chattopadhyay, S; Debnath, MC; Ganguly, S; Karmakar, S; Nayak, DK; Sachdeva, SS; Sarkar, BR | 1 |
| Artigas, G; Barrabés, S; Escribano, E; González-Cantó, A; Marchán, V; Massaguer, A; Moreno, V | 1 |
| Epple, M; Gräfe, S; Haedicke, K; Hilger, I; Kozlova, D; Teichgräber, U | 1 |
| Cai, P; Chen, X; Hong, M; Liao, LD; Liu, B; Liu, J; Thakor, N; Wang, Z; Yuan, Y | 1 |
| Chen, Z; Fu, Q; Lv, P; Ma, G; Ni, D; Wei, W; Yue, H; Yue, Z; Zhang, L | 1 |
| Chu, L; Deng, H; Deng, L; Dong, A; Huang, P; Liu, J; Liu, Q; Yang, C; Zhang, Y; Zhao, X | 1 |
| Akhtar, AM; Allen, D; Chen, X; Choudhury, RP; Hamilton, A; Jefferson, A; Larkin, JR; Melemenidis, S; Muschel, RJ; Perez-Balderas, F; Ruparelia, N; Sibson, NR; Smart, SC; Xie, J | 1 |
| Bhatt, P; Misra, A; Patil, S; Vhora, I | 1 |
| Chen, S; Li, H; Liu, M; Ren, L; Ye, C; Zhang, Z; Zhou, X | 1 |
| Barkhodari, A; Chin, F; Gambhir, SS; Iagaru, A; Jamali, M; Minamimoto, R; Mittra, E; Mosci, C; Shen, B | 1 |
| Fu, F; Shen, M; Shi, X; Xiong, Z; Zhu, J | 1 |
| Hu, K; Huang, T; Liang, X; Nie, D; Tang, G; Tang, X; Wang, H; Yao, S | 1 |
| Belvisi, L; Dal Corso, A; Gennari, C; Pignataro, L | 1 |
| Gao, H; He, Q; Liu, Y; Mei, L; Yu, Q; Zhang, Q; Zhang, Z | 1 |
| Chen, T; Huang, Y; Li, W; Yang, L; Zhou, Y | 1 |
| Aslanidi, G; Colon-Cortes, Y; Ling, C; Nolasco, D; Pandya, M; Sayroo, R; Yin, Z | 1 |
| Baguña Torres, J; Blower, PJ; Cullinane, C; Hicks, RJ; Imberti, C; Ma, MT; Roselt, P; Terry, SY | 1 |
| Belfield, KD; Githaiga, GW; Komatsu, M; Liu, X; Morales, AR; Sawada, J; Tang, S; Woodward, AW; Yue, X | 1 |
| Gai, S; Gu, R; Gulzar, A; He, F; Lv, R; Yang, G; Yang, P; Zhang, S; Zhong, C | 1 |
| Cai, J; Jiang, J; Li, Q; Wu, H; Xu, H | 1 |
| Dong, A; Huang, P; Kong, D; Liu, J; Wang, W; Zhang, Y; Zhao, F | 1 |
| Aliev, G; Rubtsov, MA; Syrkina, MS | 1 |
| Curiel, DT; Dobbins, GC; Gillespie, GY; Ugai, H | 1 |
| Corbet, C; Feron, O; Marchand-Brynaert, J; Pourcelle, V; Préat, V; Ragelle, H; Vanvarenberg, K | 1 |
| Liu, M; Liu, Z; Wang, X; Yu, L; Zeng, W; Zhang, X | 1 |
| Cai, J; Cheng, D; Li, X; Liu, S; Shi, H; Su, H; Yang, Y; Zhang, C; Zhang, J; Zhang, L; Zhang, Y | 1 |
| Li, X; Pan, L; Shi, J; Wu, M | 1 |
| Cun, X; Gao, H; He, Q; Liu, Y; Lu, L; Shi, K; Yang, Y; Zhang, L; Zhang, Q | 1 |
| Guo, L; Liu, G; Xu, X; Yao, W; Yin, R; Zhang, J; Zhang, W; Zhu, H | 1 |
| Gao, J; Lu, W; Ren, Y; Wei, X; Xie, C; Yan, Z; Ying, M; Zhang, M | 1 |
| Bhasin, S; Farokhzad, OC; Ha, E; Li, Q; Liu, Y; Shi, J; Wu, J; Xu, X; Yu, M; Zhao, L; Zhu, X | 1 |
| Cheng, H; Li, SY; Qiu, WX; Song, LL; Xie, BR; Zhang, XZ; Zhuo, RX | 1 |
| Fan, X; Wang, X; Wu, G; Zhao, F | 1 |
| Hu, JJ; Wang, SB; Xiao, D; Zhang, XZ; Zhu, JY; Zhuo, RX | 1 |
| Chen, J; Hu, Y; Li, X; Shen, M; Shi, X; Wang, H; Wei, P | 1 |
| Blower, PJ; Clarke, F; Cope, AP; Cornish, GH; Cullinane, C; Hicks, RJ; Imberti, C; Ma, MT; Ramakrishnan, NK; Roselt, P; Terry, SY | 1 |
| Dong, H; Gao, Y; Guo, H; Jiang, S; Liu, X; Qin, W; Sun, S; Teng, Z; Wei, Y; Yan, D; Yin, H | 1 |
| Bomba, HN; Gu, Z; Hu, Q; Qian, C; Sun, W; Xin, H | 1 |
| Barnes, LA; Cheresh, DA; Lutu-Fuga, K; Majeti, BK; Makale, M; Murphy, EA; Weis, SM; Wrasidlo, W | 1 |
| Lavasanifar, A; Mahmud, A; Uludağ, H; Xiong, XB | 1 |
| Guo, G; Li, W; Mao, XH; Xiao, B; Yang, J; Zou, QM | 1 |
| Castermans, K; Chin, PT; Fayad, ZA; Griffioen, AW; Kaijzel, EL; Löwik, CW; Mulder, WJ; Nicolay, K; Oude Egbrink, MG; Que, I; Storm, G; Strijkers, GJ; van Beijnum, JR | 1 |
| Barnett, J; Cuthbertson, A; Morrison, MS; Ricketts, SA; Tessier, J; Wedge, SR | 1 |
| Cheng, Z; De, A; Gambhir, SS; Hoerner, JK; Levi, J; Namavari, M; Syud, FA; Yaghoubi, SS; Zhang, R | 1 |
| Beer, AJ; Dijkgraaf, I; Wester, HJ | 1 |
| Decristoforo, C; Haubner, R | 1 |
| Chen, X; Liu, S; Liu, Z; Wang, F | 1 |
| Da Violante, G; Gourlaouen, M; Hart, IR; Hodivala-Dilke, KM; Jones, DT; Jones, MC; Kostourou, V; Norman, JC; Perron-Sierra, F; Reynolds, AR; Robinson, SD; Salih, M; Saunders, G; Silva, RG; Tucker, GC; Watson, AR; Welti, JC | 1 |
| Boerman, OC; Oyen, WJ; Ruers, TJ; Stollman, TH | 1 |
| Arap, W; Hajitou, A; Hanna, E; Henry, C; Kachala, S; Khanna, C; Leblanc, A; Libutti, SK; Mazcko, C; Newman, S; Paoloni, MC; Pasqualini, R; Sorenmo, K; Tandle, A; Thamm, D; Vail, D | 1 |
| Ballmer-Hofer, K; Cohrs, S; Fischer, E; Friedli, A; Grünberg, J; Novak-Hofer, I; Schibli, R; Schubiger, PA | 1 |
| Cheon, J; Lee, JH; Lee, K; Lee, Y; Moon, SH; Park, TG | 1 |
| Jia, B; Kim, YS; Liu, S; Shi, J; Wang, F; Wang, L; Zhai, S | 1 |
| Alemany, R; Bayo-Puxan, N; Cascallo, M; Gimenez-Alejandre, M; Gros, A; Hemminki, A; Lavilla-Alonso, S | 1 |
| Liu, S | 1 |
| Anthony, T; Hao, G; Hsieh, JT; Liu, W; Long, MA; Sun, X | 1 |
| Behera, D; Biswal, S; Chen, K; Chen, X; Michalski, MH; Wang, A; Xie, J; Xu, H | 1 |
| Nishikawa, M; Nishizaki, C; Oku, M; Sakai, Y; Takakura, Y; Yata, T; Yurimoto, H | 1 |
| Lane, SR; Nanda, PK; Pandey, US; Retzloff, LB; Smith, CJ | 1 |
| Agemy, L; Girard, OM; Hanahan, D; Karmali, PP; Kotamraju, VR; Mattrey, RF; Ruoslahti, E; Sugahara, KN; Teesalu, T | 1 |
| Han, Y; Li, Z; Ma, Y; Shen, H; Yin, D; Yu, J; Zhou, W | 1 |
| Boerman, OC; Dijkgraaf, I | 1 |
| Chen, X; Liu, S; Liu, Z; Niu, G; Wang, F | 1 |
| Cochran, JR; Deshpande, N; Gambhir, SS; Kimura, RH; Lutz, AM; Willmann, JK | 1 |
| Auzzas, L; Battistini, L; Burreddu, P; Carta, P; Casiraghi, G; Curti, C; Rassu, G; Zanardi, F | 1 |
| Jia, B; Jin, X; Li, F; Liu, S; Liu, Z; Shi, J; Wang, F; Zhao, H | 1 |
| Ferro-Flores, G; Meléndez-Alafort, L; Ramírez, Fde M; Santos-Cuevas, CL | 1 |
| Chen, KJ; Chiou, PY; Lin, WY; Ohashi, M; Tseng, HR; Wang, H; Wang, S; Wu, TH | 1 |
| Berdel, WE; Bremer, C; Dreischalück, J; Heindel, W; Hintelmann, H; Kessler, T; Liersch, R; Mesters, RM; Persigehl, T; Ring, J; Schwöppe, C | 1 |
| Feron, O | 1 |
| Chang, C; Chen, JX; Li, C; Quan, CY; Wang, HY; Zhang, XZ; Zhuo, RX | 1 |
| Boturyn, D; Dumy, P; Fujibayashi, Y; Fukumura, T; Furukawa, T; Galibert, M; Jin, ZH; Saga, T | 1 |
| Cheng, Z; De, A; Gambhir, SS; Rosenberg, J; Smith, BR | 1 |
| Chen, X; Jacobson, O; Kiesewetter, DO; Liu, S; Ma, Y; Niu, G; Sun, X; Szajek, LP; Weiss, ID; Yan, Y; Zhu, L | 1 |
| Chen, X; Jia, B; Li, F; Liu, S; Liu, Y; Liu, Z; Shi, J; Tian, J; Wang, F; Yu, Z; Zhao, H | 1 |
| Chen, X; Ma, Y; Niu, G; Ye, Y; Zhu, L | 1 |
| Allard, M; Hazari, PP; Mishra, AK; Pal, S; Stromberg, R; Uppal, JK; Varshney, R | 1 |
| Eldar-Boock, A; Lupu, R; Miller, K; Sanchis, J; Satchi-Fainaro, R; Vicent, MJ | 1 |
| Armijo, AL; Czernin, J; Ng, QK; Radu, CG; Segura, T; Su, H | 1 |
| Cheng, Z; Fan, F; Kimura, R; Liu, H; Miao, Z; Zhang, X | 1 |
| Boturyn, D; Coll, JL; Dumy, P; Fujibayashi, Y; Fukumura, T; Furukawa, T; Galibert, M; Jin, ZH; Saga, T | 1 |
| Kim, J; Kim, PH; Kim, SW; Kim, TI; Nam, HY; Ryu, J; Yun, CO | 1 |
| Cerullo, V; Diaconu, I; Dotti, G; Escutenaire, S; Guse, K; Haavisto, E; Hannuksela, P; Hemminki, A; Holm, SL; Joensuu, T; Kanerva, A; Kangasniemi, L; Karioja-Kallio, A; Karli, E; Kauppinen, S; Laasonen, L; Nokisalmi, P; Oksanen, M; Partanen, K; Pesonen, S; Raki, M | 1 |
| Huang, X; Liu, Z; Pan, L; Ren, Y; Xu, H; Yang, Y | 1 |
| Li, J; Liu, P; Xu, LX; Yang, K; Zhang, C | 1 |
| Jasti, B; Kotamraj, P; Li, X; Russu, WA; Wu, J | 1 |
| Alemany, R; Cascallo, M; Gil-Hoyos, R; Gimenez-Alejandre, M; Rojas, JJ | 1 |
| Ding, Y; Li, W; Luo, B; Meng, S; Rui, W; Yi, X; Zeng, Y; Zhao, Y; Zhou, C | 1 |
| Barragán, F; Betanzos-Lara, S; Habtemariam, A; López-Senín, P; Marchán, V; Moreno, V; Sadler, PJ; Salassa, L | 1 |
| Cai, W; Engle, JW; Hong, H; Nickles, RJ; Shi, J; Wang, X; Yang, Y; Zhang, Y | 1 |
| Jing, C; Li, Y; Long, YT; Zhang, L | 1 |
| Chen, X; Guo, N; Kiesewetter, DO; Lang, L; Li, W; Ma, Y; Niu, G; Shen, B; Zhu, L | 1 |
| Harada, H; Hiraoka, M; Kimura, A; Kuramochi, Y; Matsuoka, H; Miki, K; Ohe, K; Oride, K | 1 |
| Kim, J; Kim, PH; Kim, SW; Yun, CO | 1 |
| Chen, X; Guo, N; Kiesewetter, DO; Lang, L; Li, W; Ma, Y; Niu, G; Shen, B | 1 |
| Li, HZ; Li, LT; Pei, DS; Yang, ZX; Yin, XX; Zhang, BF; Zheng, JN | 1 |
| Lu, X; Wang, RF | 1 |
| Huang, X; Li, W; Li, Y; Liu, Z; Pan, L; Pu, C; Ren, Y; Xu, HM; Yang, Y; Zhang, C | 1 |
| Jalkanen, S; Nanni, C; Roivainen, A | 1 |
| Beer, AJ; Gaertner, FC; Kessler, H; Schwaiger, M; Wester, HJ | 1 |
| Danhier, F; Feron, O; Jérôme, C; Marchand-Brynaert, J; Pourcelle, V; Préat, V | 1 |
| Chaudhary, K; Gautam, A; Kapoor, P; Kumar, R; Raghava, GP; Singh, H | 1 |
| Bhuniya, S; Han, JH; Kang, C; Kim, JS; Kim, JY; Lee, MH; Sessler, JL | 1 |
| Inoue, T; Oka, T; Tateishi, U | 1 |
| Cal, S; Moncada-Pazos, A; Obaya, AJ; Rua, S | 1 |
| Achilefu, S; Akers, W; Bloch, S; Odonkor, C; Xu, B; Ye, Y | 1 |
| Chen, CH; Cheng, TL; Chiu, YH; Chuang, HY; Hsu, WT; Liao, KW; Lin, YL; Liu, YK | 1 |
| Czarny, B; Dubois, A; Ducongé, F; Garofalakis, A; Tavitian, B; Thézé, B | 1 |
| Belfield, KD; Biswas, S; Komatsu, M; Morales, AR; Urakami, T; Wang, X; Yanez, CO; Zhang, Y | 1 |
| Danhier, F; Le Breton, A; Préat, V | 1 |
| Kim, J; Kim, WJ; Namgung, R; Park, J; Singha, K; Son, S; Yun, CO | 1 |
| Amadei, GA; Breadner, D; Cho, CF; Lewis, JD; Luyt, LG | 1 |
| Berendsen, AD; Bos, EJ; de Leij, LF; Kok, RJ; Meijer, DK; Molema, G; Moorlag, HE; Schraa, AJ | 1 |
| Alemany, R; Curiel, DT; Suzuki, K; Yamamoto, M | 1 |
| Jiang, X; Pen, S; Wang, C; Zhao, M | 1 |
| Hill-Bator, A; Opolski, A | 1 |
| Fujii, Y; Fujimoto, Z; Horii, K; Mizuno, H; Morita, T; Okuda, D | 1 |
| Bernard, B; Breeman, W; Capello, A; de Jong, M; Erion, J; Krenning, E; Schmidt, M; Srinivasan, A; van Gameren, A; van Hagen, M | 1 |
| Fretz, MM; Koning, GA; Krijger, GC; Storm, G; Woroniecka, U | 1 |
| Botter, SM; de Leij, LF; Kok, RJ; Meijer, DK; Molema, G; Schraa, AJ; Withoff, S | 1 |
| Guedez, L; Kelly, K; Lake, R; Stetler-Stevenson, WG; Tian, L; Wang, T; Ward, Y | 1 |
| Lewis, MR | 1 |
| Capello, A; de Jong, M; Hofland, LJ; Krenning, EP; van Hagen, MP | 1 |
| Asai, T; Oku, N | 1 |
| Bakker, CT; Bosma, PJ; Lie-A-Ling, M; Wesseling, JG | 1 |
| Achilefu, S; Bloch, S; Chance, B; Dorshow, RB; Liang, K; Markiewicz, MA; Ye, Y; Zhong, T | 1 |
| Boturyn, D; Coll, JL; Dumy, P; Favrot, MC; Garanger, E; Jin, Z | 1 |
| Archimandritis, SC; Fani, M; Psimadas, D; Varvarigou, AD; Xanthopoulos, S; Zikos, C | 1 |
| Bleeker, EJ; Griffioen, AW; Habets, JW; Koning, GA; Mulder, WJ; Nicolay, K; Storm, G; Strijkers, GJ; van der Schaft, DW | 1 |
| Baker, JR; Kotlyar, A; Myc, A; Peters, J; Shukla, R; Thomas, TP | 1 |
| Kok, RJ; Molema, G; Schiffelers, RM; Temming, K | 1 |
| Arap, W; Bover, L; Cardó-Vila, M; Do, KA; Giordano, RJ; Holbeck, SL; Jaalouk, DE; Kolonin, MG; Kunyiasu, A; Lahdenranta, J; Moya, CA; Ozawa, MG; Pasqualini, R; Sausville, EA; Scudiero, DA; Souza, GR; Staquicini, FI; Sun, J; Zurita, AJ | 1 |
| Akakura, N; Chuang, CC; Lee, SC; Mori, S; Takada, Y; Wu, PL; Wu, WG | 1 |
| Beer, AJ; Goebel, M; Grosu, AL; Haubner, R; Luderschmidt, S; Martinez, MJ; Niemeyer, M; Schwaiger, M; Weber, WA; Wester, HJ; Wolf, I | 1 |
| Boutillon, M; Casara, PJ; Hickman, JA; Maubant, S; Perron-Sierra, F; Saint-Dizier, D; Tucker, GC; Van Obberghen-Schilling, E | 1 |
| Auernheimer, J; Kessler, H; Meyer, A; Modlinger, A | 1 |
| Cai, W; Chen, X | 2 |
| Ai, H; Bey, E; Boothman, DA; Chin, SF; Gao, J; Guthi, JS; Khemtong, C; Nasongkla, N; Ren, J; Sherry, AD | 1 |
| Baiula, M; Cardillo, G; Gentilucci, L; Spampinato, S; Sparta, A; Squassabia, F; Tolomelli, A | 1 |
| Carlson, CB; Dykhuizen, EC; Kiessling, LL; Mowery, P; Owen, RM | 1 |
| Borgstrom, P; Deisseroth, A; Koziol, J; Liu, Y | 1 |
| Han, W; Hao, Q; Li, L; Li, M; Li, W; Meng, J; Qin, X; Wan, Y; Wu, J; Xue, X; Yan, Z; You, Y; Zhang, C; Zhang, Y | 1 |
| Alberto, R; Decristoforo, C; Duatti, A; Haubner, R; Kuenstler, JU; Pietzsch, HJ; Rey, A; Santos, I; Smith, CJ; Von Guggenberg, E | 1 |
| Cao, L; Chen, Y; Fang, L; Hua, Z; Jin, G; Ma, D; Ye, J; Zhou, B | 1 |
| Barnés, CM; Barnes, KR; Haskel, A; Lippard, SJ; Mukhopadhyay, S; Short, SM | 1 |
| Boturyn, D; Dumy, P; Garanger, E | 1 |
| Markland, FS; Ramu, S; Swenson, S | 1 |
| Cao, L; Du, P; Hua, ZC; Huang, QL; Jiang, SH; Jin, GH | 1 |
| Dickinson, CD; Koivunen, E; Ruoslahti, E; Wang, B | 1 |
| Nicolson, GL | 1 |
| Cheresh, DA; Varner, JA | 1 |
| Iizuka, J; Katagiri, Y; Murakami, M; Uede, T | 1 |
| Hill, J; Kay, J; Powell, DJ; Smith, TS; Tatnell, PJ; Tew, DG | 1 |
| Bernard, HF; Breeman, WA; de Jong, M; Krenning, EP; Mooij, CM; Schaar, M; Schmidt, MA; Srinivasan, A; van Hagen, PM | 1 |
| Brüsselbach, S; Fahr, A; Müller, K; Müller, R; Nahde, T | 1 |
| Chakravarthy, A; Cmelak, A; Geng, L; Giorgio, T; Hallahan, DE; Martin, W; Qu, S; Scarfone, C | 1 |
| Ruoslahti, E | 1 |
44 review(s) available for arginyl-glycyl-aspartic acid and Neoplasms
| Article | Year |
|---|---|
RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy.
Topics: Dendrimers; Humans; Nanomedicine; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2021 |
Recent progress in biomedical applications of RGD-based ligand: From precise cancer theranostics to biomaterial engineering: A systematic review.
Topics: Animals; Biocompatible Materials; Biomedical Technology; Clinical Trials as Topic; Drug Delivery Systems; Gene Transfer Techniques; Humans; Ligands; Neoplasms; Oligopeptides; Theranostic Nanomedicine; Tissue Engineering | 2020 |
The Influence of Different Spacers on Biological Profile of Peptide Radiopharmaceuticals for Diagnosis and Therapy of Human Cancers.
Topics: Animals; Bombesin; Gastrins; Humans; Melanocyte-Stimulating Hormones; Neoplasms; Neurotensin; Oligopeptides; Peptides; Radiopharmaceuticals; Somatostatin | 2020 |
Biological Relevance of RGD-Integrin Subtype-Specific Ligands in Cancer.
Topics: Animals; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; Ligands; Neoplasms; Oligopeptides; Peptidomimetics; Protein Binding | 2021 |
Molecular Imaging of Angiogenesis in Oncology: Current Preclinical and Clinical Status.
Topics: Animals; Biomarkers, Tumor; Cell Hypoxia; Glucose; Humans; Integrins; Matrix Metalloproteinases; Medical Oncology; Molecular Imaging; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Tomography, Emission-Computed, Single-Photon; Vascular Endothelial Growth Factor A | 2021 |
iRGD as a tumor‑penetrating peptide for cancer therapy (Review).
Topics: Antineoplastic Agents; Doxorubicin; Drug Carriers; Humans; Integrins; Neoplasm Metastasis; Neoplasms; Oligopeptides | 2017 |
RGD peptide-based non-viral gene delivery vectors targeting integrin α
Topics: Animals; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrin alphaVbeta3; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2019 |
RGD cadherins and α2β1 integrin in cancer metastasis: A dangerous liaison.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Immunological; Binding Sites; Cadherins; Cell Adhesion; Cell Movement; Cell Proliferation; Humans; Integrin alpha2beta1; Neoplasm Metastasis; Neoplasms; Oligopeptides; Protein Binding; Receptors, Immunologic; Receptors, Peptide; Signal Transduction | 2018 |
RGD-modified polymer and liposome nanovehicles: Recent research progress for drug delivery in cancer therapeutics.
Topics: Antineoplastic Agents; Drug Delivery Systems; Humans; Liposomes; Nanostructures; Neoplasms; Oligopeptides | 2019 |
The functions and applications of RGD in tumor therapy and tissue engineering.
Topics: Animals; Biomimetic Materials; Drug Delivery Systems; Gene Transfer Techniques; Humans; Integrins; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Tissue Engineering | 2013 |
Development of RGD-based radiotracers for tumor imaging and therapy: translating from bench to bedside.
Topics: Animals; Humans; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Radiotherapy, Image-Guided; Surgery, Computer-Assisted; Tomography, Emission-Computed, Single-Photon; Translational Research, Biomedical | 2013 |
Strategies to inhibit tumor associated integrin receptors: rationale for dual and multi-antagonists.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Binding Sites; Humans; Integrins; Molecular Targeted Therapy; Neoplasms; Oligopeptides; Protein Conformation | 2014 |
Protein- and Peptide-drug conjugates: an emerging drug delivery technology.
Topics: Albumins; Antibodies; Antineoplastic Agents; Cell-Penetrating Peptides; Delayed-Action Preparations; Drug Carriers; Gelatin; Humans; Immunoconjugates; Molecular Targeted Therapy; Neoplasms; Oligopeptides; RNA, Small Interfering; Transferrin | 2015 |
αvβ3 Integrin-Targeted Peptide/Peptidomimetic-Drug Conjugates: In-Depth Analysis of the Linker Technology.
Topics: Animals; Antineoplastic Agents; Drug Carriers; Humans; Integrin alphaVbeta3; Neoplasms; Oligopeptides; Peptidomimetics | 2016 |
RGD-based Therapy: Principles of Selectivity.
Topics: Animals; Antineoplastic Agents; Drug Design; Humans; Integrins; Ligands; Molecular Targeted Therapy; Neoplasms; Oligopeptides | 2016 |
Integrin (αvβ3) Targeted RGD Peptide Based Probe for Cancer Optical Imaging.
Topics: Biomarkers, Tumor; Fluorescent Dyes; Humans; Integrin alphaVbeta3; Luminescent Measurements; Molecular Imaging; Molecular Probe Techniques; Molecular Probes; Nanoparticles; Neoplasms; Oligopeptides; Optical Imaging; Protein Multimerization | 2016 |
Application of RGD-containing peptides as imaging probes for alphavbeta3 expression.
Topics: Animals; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Molecular Probes; Neoplasms; Oligopeptides; Positron-Emission Tomography; Ultrasonography | 2009 |
Radiolabelled RGD peptides and peptidomimetics for tumour targeting.
Topics: Humans; Integrins; Molecular Mimicry; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2009 |
New targeted probes for radioimaging of angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antigens, Surface; Biomarkers, Tumor; Extracellular Matrix Proteins; Glutamate Carboxypeptidase II; Humans; Integrin alphaVbeta3; Matrix Metalloproteinases; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Radiopharmaceuticals; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A | 2009 |
Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency.
Topics: Binding Sites; Humans; Integrin alphaVbeta3; Neoplasms; Oligopeptides; Peptides, Cyclic; Radioisotopes; Radionuclide Imaging; Tissue Distribution | 2009 |
Radiolabeled regulatory peptides for imaging and therapy.
Topics: Humans; Molecular Imaging; Neoplasms; Oligopeptides; Peptides; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Bombesin; Receptors, Melanocortin; Receptors, Peptide; Receptors, Somatostatin | 2010 |
Radionuclide imaging of tumor angiogenesis.
Topics: Alternative Splicing; Angiogenesis Inhibitors; Animals; Endothelium, Vascular; Fluorodeoxyglucose F18; Humans; Indium Radioisotopes; Integrin alphaVbeta3; Magnetic Resonance Imaging; Matrix Metalloproteinases; Mice; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Receptors, Immunologic; Receptors, Peptide; Receptors, Vascular Endothelial Growth Factor | 2009 |
Targeting alphavbeta3 integrin: design and applications of mono- and multifunctional RGD-based peptides and semipeptides.
Topics: Antineoplastic Agents; Drug Design; Humans; Integrin alphaVbeta3; Ligands; Neoplasms; Oligopeptides; Peptides | 2010 |
Peptides for in vivo target-specific cancer imaging.
Topics: Animals; Fluorescent Dyes; Gene Products, tat; Humans; Magnetic Resonance Imaging; Molecular Imaging; Nanoparticles; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Quantum Dots; Receptors, Peptide; Tomography, Emission-Computed, Single-Photon | 2010 |
Resonance scattering particles as biological nanosensors in vitro and in vivo.
Topics: Amyloid; Animals; Biosensing Techniques; Energy Transfer; Humans; Nanoparticles; Neoplasms; Oligopeptides; Surface Plasmon Resonance | 2012 |
Enhancing the therapeutic efficacy of adenovirus in combination with biomaterials.
Topics: Adenoviridae; Animals; Biocompatible Materials; Chitosan; Genetic Therapy; Humans; Ligands; Liposomes; Methacrylates; Mice; Neoplasms; Oligopeptides; Peptides; Polyethylene Glycols; Polyethyleneimine; Polylysine; Polymers | 2012 |
A concise review of current radiopharmaceuticals in tumor angiogenesis imaging.
Topics: Amino Acid Sequence; Animals; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2012 |
Gallium-labelled peptides for imaging of inflammation.
Topics: Amine Oxidase (Copper-Containing); Animals; Atherosclerosis; Cell Adhesion Molecules; Fracture Healing; Gallium Radioisotopes; Humans; Infections; Inflammation; Integrin alphaVbeta3; Mice; Mice, Knockout; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Receptors, Somatostatin | 2012 |
Radiolabelled RGD peptides for imaging and therapy.
Topics: Angiogenesis Inhibitors; Copper Radioisotopes; Galactose; Gallium Radioisotopes; Humans; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Peptides; Peptides, Cyclic; Polyethylene Glycols; Radiopharmaceuticals; Technetium; Tomography, Emission-Computed, Single-Photon | 2012 |
Radiolabeled RGD peptides as integrin alpha(v)beta3-targeted PET tracers.
Topics: Animals; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Isotope Labeling; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radioactive Tracers | 2012 |
RGD-based strategies to target alpha(v) beta(3) integrin in cancer therapy and diagnosis.
Topics: Humans; Integrin alphaVbeta3; Neoplasms; Oligopeptides; Radiopharmaceuticals | 2012 |
A review of RGD-functionalized nonviral gene delivery vectors for cancer therapy.
Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Endothelium; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Polyethylene Glycols | 2012 |
[Biological activity of synthetic analogs of laminin active sequences: YIGSR, RGD, SIKVAV].
Topics: Animals; Antineoplastic Agents; Humans; Laminin; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neoplastic Processes; Neovascularization, Pathologic; Oligopeptides; Platelet Aggregation; Thrombosis | 2002 |
Induction of apoptosis with hybrids of Arg-Gly-Asp molecules and peptides and antimitotic effects of hybrids of cytostatic drugs and peptides.
Topics: Animals; Antineoplastic Agents; Apoptosis; Humans; Mitosis; Neoplasms; Oligopeptides; Peptides; Receptors, Somatostatin; Treatment Outcome | 2005 |
RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Doxorubicin; Drug Carriers; Endothelial Cells; Genetic Therapy; Genetic Vectors; Humans; Integrin alphaVbeta3; Mutation; Neoplasms; Oligopeptides; Peptides, Cyclic; Polyethylene Glycols; Recombinant Proteins; RNA, Small Interfering; Transfection; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2005 |
Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting.
Topics: Animals; Drug Delivery Systems; Drug Design; Humans; Integrins; Neoplasms; Oligopeptides; Technology, Pharmaceutical | 2006 |
Anti-angiogenic cancer therapy based on integrin alphavbeta3 antagonism.
Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disintegrins; Drug Delivery Systems; Gene Silencing; Gene Targeting; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Neoplasms; Oligopeptides; Positron-Emission Tomography; RNA, Small Interfering; Snake Venoms; Tomography, Emission-Computed, Single-Photon; Ultrasonography | 2006 |
Tumor targeting with RGD peptide ligands-design of new molecular conjugates for imaging and therapy of cancers.
Topics: Animals; Drug Delivery Systems; Drug Design; Humans; Integrin alphaVbeta3; Ligands; Neoplasms; Oligopeptides; Tissue Distribution | 2007 |
Anti-angiogenesis and RGD-containing snake venom disintegrins.
Topics: Angiogenesis Inhibitors; Animals; Disintegrins; Humans; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Snake Venoms | 2007 |
Tumor cell interactions with the vascular endothelium and their role in cancer metastasis.
Topics: Amino Acid Sequence; Animals; Cell Adhesion; Cell Differentiation; Cell Movement; Endothelium, Vascular; Growth Inhibitors; Growth Substances; Humans; Microcirculation; Models, Biological; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Oligopeptides | 1995 |
Tumor angiogenesis and the role of vascular cell integrin alphavbeta3.
Topics: Adult; Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Child; Clinical Trials, Phase II as Topic; Endothelial Growth Factors; Extracellular Matrix Proteins; Eye Diseases; Female; Fibroblast Growth Factors; Humans; Inflammation; Lymphokines; Male; Metalloendopeptidases; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Receptors, Vitronectin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
Osteopontin, a coordinator of host defense system: a cytokine or an extracellular adhesive protein?
Topics: Amino Acid Sequence; Animals; Cardiovascular Physiological Phenomena; Humans; Hyaluronan Receptors; Mice; Molecular Sequence Data; Neoplasm Metastasis; Neoplasms; Oligopeptides; Osteopontin; Protein Binding; Protein Conformation; Rats; Sialoglycoproteins; Signal Transduction; Urinary Tract Physiological Phenomena | 1997 |
Radiation-mediated control of drug delivery.
Topics: Animals; Antineoplastic Agents; Bacterial Proteins; Clinical Trials, Phase I as Topic; Drug Delivery Systems; Drug Evaluation, Preclinical; Electromagnetic Phenomena; Fibrinogen; Genetic Therapy; Humans; Immunoconjugates; Ligands; Liposomes; Microspheres; Neoplasms; Oligopeptides; Peptide Library; Radiation-Sensitizing Agents; Radiation, Ionizing; Radioimmunotherapy; Receptors, Immunologic; Receptors, Peptide; Repressor Proteins | 2001 |
Integrins.
Topics: Animals; Humans; Integrins; Leukocytes; Neoplasms; Oligopeptides; Platelet Membrane Glycoproteins; Wound Healing | 1991 |
3 trial(s) available for arginyl-glycyl-aspartic acid and Neoplasms
| Article | Year |
|---|---|
Biodistribution of the ¹⁸F-FPPRGD₂ PET radiopharmaceutical in cancer patients: an atlas of SUV measurements.
Topics: Biological Transport; Female; Humans; Male; Middle Aged; Neoplasms; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution | 2015 |
Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature.
Topics: Adenoviridae; Animals; Dogs; Genetic Therapy; Genetic Vectors; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Treatment Outcome; Tumor Necrosis Factor-alpha | 2009 |
Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors.
Topics: Adenoviridae; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; DNA, Viral; Drug Resistance, Neoplasm; Fatigue; Female; Fever; Genetic Vectors; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Integrins; Male; Middle Aged; Neoplasms; Oligopeptides; Oncolytic Virotherapy; Oncolytic Viruses; Real-Time Polymerase Chain Reaction; Treatment Outcome; Viral Load; Virus Replication | 2012 |
196 other study(ies) available for arginyl-glycyl-aspartic acid and Neoplasms
| Article | Year |
|---|---|
A multifunctional AIE gold cluster-based theranostic system: tumor-targeted imaging and Fenton reaction-assisted enhanced radiotherapy.
Topics: Animals; Cell Line, Tumor; Cell Survival; Female; Ferric Compounds; Gold; Humans; Hydrogen Peroxide; Iron; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Oligopeptides; Photochemotherapy; Radiation-Sensitizing Agents; Theranostic Nanomedicine; Tissue Distribution | 2021 |
Covalent RGD-graphene-phthalocyanine nanocomposite for fluorescence imaging-guided dual active/passive tumor-targeted combinatorial phototherapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Female; Fluorescent Dyes; Graphite; HEK293 Cells; Humans; Isoindoles; Light; Mice; Nanocomposites; Nanoparticles; Neoplasms; Oligopeptides; Optical Imaging; Photochemotherapy; Photosensitizing Agents; Phototherapy; Singlet Oxygen | 2022 |
Attenuated Salmonella Typhimurium with truncated LPS and outer membrane-displayed RGD peptide for cancer therapy.
Topics: Animals; Endostatins; Integrin alphaV; Lipid A; Lipopolysaccharides; Mice; Neoplasms; O Antigens; Peptides; Salmonella typhimurium | 2022 |
Cationic RGD peptidomimetic nanoconjugates as effective tumor targeting gene delivery vectors with antimicrobial potential.
Topics: Anti-Infective Agents; Antineoplastic Agents; Cations; Gene Transfer Techniques; Genes, Neoplasm; Genetic Therapy; Genetic Vectors; Humans; Nanoconjugates; Neoplasms; Oligopeptides; Peptidomimetics | 2022 |
Lasso peptide microcin J25 variant containing RGD motif as a PET probe for integrin a v ß 3 in tumor imaging.
Topics: Animals; Escherichia coli; Integrin alphaVbeta3; Lysine; Mice; Molecular Probes; Neoplasms; Positron-Emission Tomography; Tissue Distribution | 2023 |
pH/Redox Dual-Responsive Drug Delivery System with on-Demand RGD Exposure for Photochemotherapy of Tumors.
Topics: Docetaxel; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Micelles; Neoplasms; Oligopeptides; Oxidation-Reduction; Photochemotherapy; Tumor Microenvironment | 2022 |
RGD Peptide-Conjugated Dodecaborate with the Ga-DOTA Complex: A Preliminary Study for the Development of Theranostic Agents for Boron Neutron Capture Therapy and Its Companion Diagnostics.
Topics: Albumins; Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Iodine Radioisotopes; Mice; Neoplasms; Precision Medicine; Tissue Distribution | 2022 |
Synthesis of Novel Carborane-Containing Derivatives of RGD Peptide.
Topics: Boranes; Humans; Neoplasms; Oligopeptides; Peptides | 2023 |
Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake.
Topics: Animals; Cell Line, Tumor; Cytoplasm; Drug Delivery Systems; Endocytosis; Humans; Ligands; Neoplasms; Oligopeptides; Polyethylene Glycols; Signal Transduction; Silicon Dioxide; Surface Properties | 2019 |
Targeting tumor cells and neovascularization using RGD-functionalized magnetoliposomes.
Topics: Animals; Cell Line, Tumor; Dynamic Light Scattering; Female; Humans; Integrin alphaVbeta3; Liposomes; Magnetic Phenomena; Magnetic Resonance Imaging; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Optical Imaging; Xenograft Model Antitumor Assays | 2019 |
A blood cell repelling and tumor cell capturing surface for high-purity enrichment of circulating tumor cells.
Topics: Blood Cells; Cell Adhesion; Cell Separation; Cell Survival; Folic Acid; HeLa Cells; Humans; Liquid Biopsy; MCF-7 Cells; Microfluidic Analytical Techniques; Neoplasms; Neoplastic Cells, Circulating; Oligopeptides; Polyethylene Glycols | 2019 |
Targeted Therapeutic-Immunomodulatory Nanoplatform Based on Noncrystalline Selenium.
Topics: Animals; Cell Line, Tumor; Humans; Immunity, Cellular; Immunomodulation; Metal Nanoparticles; Mice; Neoplasms; Oligopeptides; Selenium; Silicon Dioxide | 2019 |
RGD conjugated switch on near infrared-fluorophores for fluorescence guided cancer surgeries.
Topics: Fluorescent Dyes; Humans; Neoplasms; Oligopeptides; Optical Imaging; Surgery, Computer-Assisted | 2019 |
Unravelling Receptor and RGD Motif Dependence of Retargeted Adenoviral Vectors using Advanced Tumor Model Systems.
Topics: Adenoviridae; Amino Acid Motifs; Capsid Proteins; Cell Culture Techniques; Cell Line, Tumor; Coculture Techniques; Epithelial Cell Adhesion Molecule; ErbB Receptors; Fibroblasts; Genetic Therapy; Genetic Vectors; Humans; Lab-On-A-Chip Devices; Neoplasms; Oligopeptides; Spheroids, Cellular; Transduction, Genetic; Virus Internalization | 2019 |
c(RGDfK)- and ZnTriMPyP-Bound Polymeric Nanocarriers for Tumor-Targeted Photodynamic Therapy.
Topics: Cell Line, Tumor; Drug Carriers; Humans; Integrins; Kinetics; Nanoparticles; Neoplasms; Oligopeptides; Photochemotherapy; Photosensitizing Agents; Polymers; Singlet Oxygen; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2020 |
Polypeptide-rhodamine B probes containing laminin/fibronectin receptor-targeting sequence (YIGSR/RGD) for fluorescent imaging in cancers.
Topics: Animals; Cell Line, Tumor; Female; Fluorescent Dyes; Laminin; Mice, Inbred BALB C; Microscopy, Fluorescence; Neoplasms; Oligopeptides; Optical Imaging; Receptors, Fibronectin; Rhodamines | 2020 |
Gold nanostars for cancer cell-targeted SERS-imaging and NIR light-triggered plasmonic photothermal therapy (PPTT) in the first and second biological windows.
Topics: A549 Cells; Cell Survival; Gold; Humans; Light; Nanostructures; Neoplasms; Oligopeptides; Phototherapy; Spectrum Analysis, Raman | 2019 |
Design of integrin α
Topics: Animals; Antineoplastic Agents; bcl-2 Homologous Antagonist-Killer Protein; Cell Proliferation; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Female; Humans; Inhibitory Concentration 50; Integrin alphaVbeta3; MCF-7 Cells; Mice; Nanoparticles; Neoplasms; Oligopeptides; Particle Size; Rats | 2020 |
Marriage of black phosphorus and Cu
Topics: Animals; Cell Death; Cell Line, Tumor; Combined Modality Therapy; Copper; Humans; Hyperthermia, Induced; Ions; Mice; Nanostructures; Neoplasms; Oligopeptides; Phosphorus; Phototherapy; Polyethylene Glycols; Positron-Emission Tomography; Spectrophotometry, Ultraviolet; Theranostic Nanomedicine | 2020 |
Two-photon photodynamic ablation of tumour cells using an RGD peptide-conjugated ruthenium(ii) photosensitiser.
Topics: Animals; Cell Line, Tumor; Coordination Complexes; Humans; Mice; Mice, Nude; Mitochondria; Neoplasms; Oligopeptides; Photochemotherapy; Photons; Photosensitizing Agents; Reactive Oxygen Species; Ruthenium; Transplantation, Heterologous | 2020 |
Glycocalyx regulates the strength and kinetics of cancer cell adhesion revealed by biophysical models based on high resolution label-free optical data.
Topics: Biophysical Phenomena; Biosensing Techniques; Cell Adhesion; Chondroitin ABC Lyase; Chondroitin Sulfates; Dermatan Sulfate; Focal Adhesions; Glycocalyx; HeLa Cells; Humans; Integrins; Kinetics; Models, Biological; Neoplasms; Oligopeptides | 2020 |
Tumor acidic microenvironment-induced drug release of RGD peptide nanoparticles for cellular uptake and cancer therapy.
Topics: Animals; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Nanoparticles; Neoplasms; Oligopeptides | 2021 |
Targeted NIR-II emissive nanoprobes for tumor detection in mice and rabbits.
Topics: Animals; Brain; Disease Models, Animal; Fluorescent Dyes; Indocyanine Green; Mice; Nanoparticles; Neoplasms; Oligopeptides; Rabbits; Spectroscopy, Near-Infrared | 2021 |
Topics: Animals; Astatine; Cell Line, Tumor; Drug Stability; Gallium Radioisotopes; Humans; Mice; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Xenograft Model Antitumor Assays | 2021 |
Hyaluronic acid and Arg-Gly-Asp peptide modified Graphene oxide with dual receptor-targeting function for cancer therapy.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Delayed-Action Preparations; Doxorubicin; Drug Delivery Systems; Graphite; Humans; Hyaluronan Receptors; Hyaluronic Acid; Integrins; Neoplasms; Oligopeptides; Oxides | 2017 |
RGD delivery of truncated coagulase to tumor vasculature affords local thrombotic activity to induce infarction of tumors in mice.
Topics: Animals; Bacterial Proteins; Cell Line, Tumor; Cells, Cultured; Coagulase; Humans; Infarction; Mice, Inbred C57BL; Mice, Nude; Mutation; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Recombinant Fusion Proteins; Thrombosis; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
An RGD-modified hollow silica@Au core/shell nanoplatform for tumor combination therapy.
Topics: Animals; Cell Line, Tumor; Doxorubicin; Gold; Humans; Mice; Nanoparticles; Neoplasms; Oligopeptides; Porosity; Silicon Dioxide; Xenograft Model Antitumor Assays | 2017 |
RGD peptide-modified fluorescent gold nanoclusters as highly efficient tumor-targeted radiotherapy sensitizers.
Topics: Animals; Drug Delivery Systems; Fluorescent Dyes; Gold; HeLa Cells; Humans; MCF-7 Cells; Metal Nanoparticles; Mice, Inbred BALB C; Neoplasms; Oligopeptides; Radiation-Sensitizing Agents | 2017 |
RGD-QD-MoS
Topics: Animals; Fluorescence; HeLa Cells; Hot Temperature; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanostructures; Neoplasms; Oligopeptides; Phototherapy; Quantum Dots; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2017 |
Novel c(RGDyK)-based conjugates of POPAM and 5-fluorouracil for integrin-targeted cancer therapy.
Topics: A549 Cells; Amino Acid Sequence; Aniline Mustard; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Fluorouracil; Humans; Integrins; Magnetic Resonance Spectroscopy; MCF-7 Cells; Neoplasms; Oligopeptides; Peptides, Cyclic; Propionates | 2017 |
Dimeric camptothecin-loaded RGD-modified targeted cationic polypeptide-based micelles with high drug loading capacity and redox-responsive drug release capability.
Topics: Camptothecin; Cations; Drug Carriers; Drug Liberation; Humans; MCF-7 Cells; Micelles; Neoplasms; Oligopeptides; Oxidation-Reduction; Peptides; Polyethylene Glycols | 2017 |
Failure of active targeting by a cholesterol-anchored ligand and improvement by altering the lipid composition to prevent ligand desorption.
Topics: Animals; Cell Line, Tumor; Cholesterol; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Ligands; Lipids; Liposomes; Mice; Mice, Inbred BALB C; Neoplasms; Oligopeptides; Peptides; Polyethylene Glycols; RNA, Small Interfering | 2018 |
Multimodal tumor-homing chitosan oligosaccharide-coated biocompatible palladium nanoparticles for photo-based imaging and therapy.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Chitosan; Humans; Lasers; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Multimodal Imaging; Neoplasms; Oligopeptides; Oligosaccharides; Palladium; Photochemotherapy; Tissue Distribution; Transplantation, Heterologous | 2018 |
Effective deactivation of A549 tumor cells in vitro and in vivo by RGD-decorated chitosan-functionalized single-walled carbon nanotube loading docetaxel.
Topics: A549 Cells; Animals; Antineoplastic Agents; Cell Survival; Chitosan; Docetaxel; Drug Carriers; Drug Liberation; Female; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Nanotubes, Carbon; Neoplasms; Oligopeptides; Taxoids; Tumor Burden; Xenograft Model Antitumor Assays | 2018 |
Co-administration of kla-TAT peptide and iRGD to enhance the permeability on A549 3D multiple sphere cells and accumulation on xenograft mice.
Topics: A549 Cells; Amino Acid Sequence; Animals; Cell Cycle Checkpoints; Cell Survival; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neuropilin-1; Oligopeptides; Peptide Fragments; Peptides; Permeability; tat Gene Products, Human Immunodeficiency Virus; Transplantation, Heterologous | 2018 |
Multiarm Nanoconjugates for Cancer Cell-Targeted Delivery of Photosensitizers.
Topics: 3T3 Cells; Animals; Apoptosis; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Mice; Nanoconjugates; Neoplasms; Oligopeptides; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Spheroids, Cellular | 2018 |
Design and Development of Polysaccharide-Doxorubicin-Peptide Bioconjugates for Dual Synergistic Effects of Integrin-Targeted and Cell-Penetrating Peptides for Cancer Chemotherapy.
Topics: Animals; Antibiotics, Antineoplastic; Arginine; Carboxymethylcellulose Sodium; Cell Line, Tumor; Cell-Penetrating Peptides; Chickens; Doxorubicin; Drug Carriers; Drug Delivery Systems; HEK293 Cells; Humans; Integrins; Neoplasms; Oligopeptides | 2018 |
Lipid insertion enables targeted functionalization of paclitaxel-loaded erythrocyte membrane nanosystem by tumor-penetrating bispecific recombinant protein.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Drug Delivery Systems; ErbB Receptors; Erythrocyte Membrane; Erythrocytes; Fluorescence; Humans; Lipids; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Oligopeptides; Paclitaxel; Phosphatidylethanolamines; Polyethylene Glycols; Recombinant Proteins; Tissue Distribution | 2018 |
Studying the chemical reactivity properties of the target tumor-environment tripeptides NGR (asparagine-glycine-arginine) and RGD (arginine-glycine-aspartic acid) in their interactions with tamoxifen through conceptual density functional theory.
Topics: Antineoplastic Agents, Hormonal; Cell Survival; Density Functional Theory; Drug Liberation; Humans; Models, Molecular; Nanodiamonds; Neoplasms; Oligopeptides; Protein Binding; Tamoxifen; Thermodynamics; Tumor Microenvironment | 2018 |
A sequentially responsive and structure-transformable nanoparticle with a comprehensively improved 'CAPIR cascade' for enhanced antitumor effect.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Liberation; Humans; Hydrogen-Ion Concentration; Matrix Metalloproteinase 9; MCF-7 Cells; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Nanoparticles; Neoplasms; Oligopeptides; Optical Imaging; Particle Size; Tumor Microenvironment | 2019 |
Microfluidics-Prepared Uniform Conjugated Polymer Nanoparticles for Photo-Triggered Immune Microenvironment Modulation and Cancer Therapy.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Cytokines; Female; Lasers; Mice; Mice, Inbred BALB C; Microfluidics; Nanoparticles; Neoplasms; Oligopeptides; Phototherapy; Polymers; RAW 264.7 Cells; T-Lymphocytes, Cytotoxic; Transplantation, Homologous | 2019 |
Sequential Delivery and Cascade Targeting of Peptide Therapeutics for Triplexed Synergistic Therapy with Real-Time Monitoring Shuttled by Magnetic Gold Nanostars.
Topics: Animals; Apoptosis; Drug Carriers; Ferrosoferric Oxide; Gold; HeLa Cells; Humans; Hyperthermia, Induced; Infrared Rays; Magnetics; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Nanostructures; Neoplasms; Oligopeptides; Peptides; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays | 2019 |
Design of an Amphiphilic Poly(aspartamide)-mediated Self-assembled Nanoconstruct for Long-Term Tumor Targeting and Bioimaging.
Topics: Amines; Animals; Cell Line, Tumor; Doxorubicin; Gene Expression Regulation, Neoplastic; Glycine; Humans; Indoles; Integrins; Mice; Nanoparticles; Neoplasms; Oligopeptides; Peptides; Polyethylene Glycols; Polymers; Xenograft Model Antitumor Assays | 2019 |
A photo-inducible protein-inorganic nanoparticle assembly for active targeted tumour theranostics.
Topics: Animals; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Male; Mice; Mice, Inbred BALB C; Microscopy, Atomic Force; Muramidase; Nanoparticles; Neoplasms; Oligopeptides; Paclitaxel; Polyethylene Glycols; Quantum Dots; Theranostic Nanomedicine; Tissue Distribution; Transplantation, Heterologous; Ultraviolet Rays | 2019 |
Engineered Cell-Assisted Photoactive Nanoparticle Delivery for Image-Guided Synergistic Photodynamic/Photothermal Therapy of Cancer.
Topics: Animals; Cell Line, Tumor; Female; Humans; Ketones; Lasers; Mice; Mice, Inbred BALB C; Mice, Nude; Monocytes; Nanoparticles; Neoplasms; Oligopeptides; Peptides, Cyclic; Photochemotherapy; Photosensitizing Agents; Phototherapy; Pyrroles; Quantum Theory; Singlet Oxygen; Transplantation, Heterologous | 2019 |
A photo-triggered conjugation approach for attaching RGD ligands to biodegradable mesoporous silica nanoparticles for the tumor fluorescent imaging.
Topics: Animals; Cell Death; Cell Line, Tumor; Cell Survival; Endocytosis; Humans; Ligands; Light; Lysine; Mice; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Oligopeptides; Porosity; Silicon Dioxide; Tissue Distribution; Toxicity Tests, Acute | 2019 |
Specific high affinity interaction of Helicobacter pylori CagL with integrin α
Topics: Antigens, Bacterial; Antigens, Neoplasm; Bacterial Proteins; Helicobacter Infections; Helicobacter pylori; Host-Pathogen Interactions; Humans; Integrins; Interleukin-8; Neoplasms; Oligopeptides; Protein Binding; Protein Transport; Tumor Cells, Cultured; Type IV Secretion Systems | 2019 |
Antitumor Potential of Fibulin-5 in Breast Cancer Cells Depends on Its RGD Cell Adhesion Motif.
Topics: Animals; Breast Neoplasms; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Extracellular Matrix Proteins; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Neoplasms; Oligopeptides; Recombinant Proteins; Transplantation, Homologous; Vimentin | 2019 |
Kiss and Run: Promoting Effective and Targeted Cellular Uptake of a Drug Delivery Vehicle Composed of an Integrin-Targeting Diketopiperazine Peptidomimetic and a Cell-Penetrating Peptide.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell-Penetrating Peptides; Diketopiperazines; Drug Carriers; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Neoplasms; Oligopeptides; Peptidomimetics | 2019 |
Mussel-inspired functionalization of semiconducting polymer nanoparticles for amplified photoacoustic imaging and photothermal therapy.
Topics: Animals; Cell Survival; Female; HeLa Cells; Humans; Lasers; Mice; Mice, Nude; Nanoparticles; Neoplasms; Oligopeptides; Photoacoustic Techniques; Phototherapy; Polyethylene Glycols; Polymers; Semiconductors | 2019 |
The effect of liposomal size on the targeted delivery of doxorubicin to Integrin αvβ3-expressing tumor endothelial cells.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Shape; Doxorubicin; Drug Delivery Systems; Drug Resistance, Neoplasm; Endocytosis; Endothelial Cells; Humans; Integrin alphaVbeta3; Liposomes; Male; Mice; Mice, Inbred BALB C; Neoplasms; Oligopeptides; Organ Specificity; Particle Size; Polyethylene Glycols; Tissue Distribution | 2013 |
Synthesis, characterization, and biological evaluation of (99m) Tc(CO)3 -labeled peptides for potential use as tumor targeted radiopharmaceuticals.
Topics: Amino Acid Sequence; Animals; Blood Proteins; Cell Line, Tumor; Half-Life; Mice; Neoplasms; Oligopeptides; Organotechnetium Compounds; Peptides; Protein Binding; Radiopharmaceuticals; Rats; Tissue Distribution; Transplantation, Heterologous | 2014 |
Targeted delivery of photosensitizers: efficacy and selectivity issues revealed by multifunctional ORMOSIL nanovectors in cellular systems.
Topics: Antibodies, Neoplasm; Drug Delivery Systems; ErbB Receptors; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Nanoparticles; Neoplasms; Oligopeptides; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Siloxanes | 2013 |
Multifunctional gold nanostar conjugates for tumor imaging and combined photothermal and chemo-therapy.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Doxorubicin; Drug Therapy; Gold; Humans; Mice; Nanostructures; Neoplasms; Oligopeptides; Phenylacetates; Photochemotherapy; Receptors, Immunologic; Receptors, Peptide | 2013 |
Tumor growth inhibition through targeting liposomally bound curcumin to tumor vasculature.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Drug Delivery Systems; Female; Human Umbilical Vein Endothelial Cells; Humans; Liposomes; Mice; Mice, Inbred C57BL; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2013 |
Label-free luminescent mesoporous silica nanoparticles for imaging and drug delivery.
Topics: Antineoplastic Agents; Biological Products; Cell Line, Tumor; Doxorubicin; Drug Carriers; Humans; Nanoparticles; Neoplasms; Oligopeptides; Optical Imaging; Silicon Dioxide | 2013 |
Synthesis and in vitro photodynamic activities of an integrin-targeting cRGD-conjugated zinc(II) phthalocyanine.
Topics: Apoptosis; Cell Line, Tumor; Coordination Complexes; Humans; Indoles; Integrins; Isoindoles; MCF-7 Cells; Microscopy, Fluorescence; Neoplasms; Oligopeptides; Organometallic Compounds; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Zinc Compounds | 2014 |
(18)F-alfatide II and (18)F-FDG dual-tracer dynamic PET for parametric, early prediction of tumor response to therapy.
Topics: Albumin-Bound Paclitaxel; Albumins; Animals; Antineoplastic Agents; Doxorubicin; Female; Fluorodeoxyglucose F18; Humans; Mice; Mice, Nude; Neoplasms; Oligopeptides; Paclitaxel; Peptides, Cyclic; Positron-Emission Tomography; Radiopharmaceuticals; Time Factors | 2014 |
RGD decoration of PEGylated polyester nanocapsules of perfluorooctyl bromide for tumor imaging: influence of pre or post-functionalization on capsule morphology.
Topics: Animals; Cell Line, Tumor; Contrast Media; Cryoelectron Microscopy; Female; Fluorine-19 Magnetic Resonance Imaging; Fluorocarbons; Hydrocarbons, Brominated; Mice, Nude; Microscopy, Electron, Transmission; Nanocapsules; Neoplasms; Oligopeptides; Particle Size; Polyethylene Glycols; Surface Properties | 2014 |
A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity.
Topics: Amino Acid Sequence; Animals; Cysteine; Drug Delivery Systems; Half-Life; Mice; Mice, Inbred BALB C; Neoplasms; Oligopeptides | 2014 |
Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging.
Topics: Administration, Intravenous; Animals; Cell Line, Tumor; Contrast Media; Disease Models, Animal; Drug Delivery Systems; Feces; Gadolinium DTPA; Humans; Liver; Lung; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Nanospheres; Neoplasm Transplantation; Neoplasms; Oligopeptides; Polystyrenes; Silicon Dioxide; Tissue Distribution; Ultrasonography | 2014 |
A radiofluorinated divalent cystine knot peptide for tumor PET imaging.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cysteine; Cystine-Knot Miniproteins; Epitopes; Female; Fluorine Radioisotopes; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Integrin alphaVbeta3; Liver; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Transplantation; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Protease Inhibitors; Protein Binding; Trypsin | 2014 |
Polyglycerol-coated nanodiamond as a macrophage-evading platform for selective drug delivery in cancer cells.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Drug Carriers; Drug Delivery Systems; Glycerol; Humans; Liposomes; Macrophages; Nanodiamonds; Neoplasms; Oligopeptides; Phagocytosis; Polymers; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; U937 Cells | 2014 |
The aspect ratio of nanoparticle assemblies and the spatial arrangement of ligands can be optimized to enhance the targeting of cancer cells.
Topics: Animals; Cell Line, Tumor; Comovirus; Drug Delivery Systems; Ligands; Mammals; Nanoparticles; Neoplasms; Oligopeptides | 2014 |
Tumor vasculature targeted photodynamic therapy for enhanced delivery of nanoparticles.
Topics: Animals; Cell Line, Tumor; Doxorubicin; Drug Carriers; Electron Spin Resonance Spectroscopy; Ferritins; Humans; Mice; Microscopy, Fluorescence; Nanomedicine; Nanoparticles; Neoplasms; Oligopeptides; Oxygen; Permeability; Photochemotherapy; Polyethylene Glycols; Quantum Dots | 2014 |
Tumor targeting RGD conjugated bio-reducible polymer for VEGF siRNA expressing plasmid delivery.
Topics: Cell Line; Cell Line, Tumor; Gene Transfer Techniques; Humans; Neoplasms; Oligopeptides; Oxidation-Reduction; Plasmids; Polymers; RNA Interference; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2014 |
Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors.
Topics: Amidines; Animals; Cholesterol; Cross-Linking Reagents; Disulfides; Endocytosis; Female; Gene Transfer Techniques; HeLa Cells; Humans; Ions; Light; Mice, Nude; Micelles; Neoplasms; Oligopeptides; Peptides, Cyclic; Polyethylene Glycols; Polylysine; Proton Magnetic Resonance Spectroscopy; RNA, Small Interfering; Scattering, Radiation | 2014 |
Hybrid polymer micelles capable of cRGD targeting and pH-triggered surface charge conversion for tumor selective accumulation and promoted uptake.
Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Cell Line, Tumor; Cell Survival; Doxorubicin; Hydrogen-Ion Concentration; Imidazoles; Mice, Inbred BALB C; Micelles; Neoplasms; Oligopeptides; Polymers; Surface Properties | 2014 |
Tumor penetrability and anti-angiogenesis using iRGD-mediated delivery of doxorubicin-polymer conjugates.
Topics: Angiogenesis Inhibitors; Animals; Area Under Curve; Capillary Permeability; Cell Line, Tumor; Cell-Penetrating Peptides; Dendrimers; Doxorubicin; Drug Delivery Systems; Endocytosis; Humans; Inhibitory Concentration 50; Kaplan-Meier Estimate; Male; Mice, Inbred ICR; Neoplasms; Oligopeptides; Polyethylene Glycols; Polymers; Tissue Distribution; Treatment Outcome | 2014 |
(44)Sc: an attractive isotope for peptide-based PET imaging.
Topics: Amino Acid Motifs; Animals; Binding, Competitive; Calcium; Cell Line, Tumor; Disease Models, Animal; Heterocyclic Compounds, 1-Ring; Humans; Image Processing, Computer-Assisted; Inhibitory Concentration 50; Integrin alphaVbeta3; Mice; Molecular Imaging; Neoplasm Transplantation; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Radioisotopes; Scandium; Tissue Distribution | 2014 |
Dye-loaded ferritin nanocages for multimodal imaging and photothermal therapy.
Topics: Animals; Cell Line, Tumor; Ferritins; Fluorescent Dyes; Indocyanine Green; Lasers; Mice; Microscopy, Atomic Force; Microscopy, Fluorescence; Nanostructures; Neoplasms; Oligopeptides; Particle Size; Photochemotherapy; Photosensitizing Agents; Tissue Distribution; Transplantation, Homologous; Ultrasonography | 2014 |
Characterization of tumor-targeting Ag2S quantum dots for cancer imaging and therapy in vivo.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Diagnostic Imaging; Doxorubicin; Female; Fluorescent Dyes; Humans; MCF-7 Cells; Mice; Mice, Nude; Molecular Imaging; Nanoconjugates; Nanomedicine; Neoplasms; Oligopeptides; Optics and Photonics; Peptides; Quantum Dots; Silver Compounds | 2014 |
Synthesis and evaluation of technetium-99m-labeled bioreductive pharmacophores conjugated with amino acids and peptides for tumor imaging.
Topics: Amino Acids; Animals; Cell Line, Tumor; Mice; Molecular Imaging; Neoplasms; Oligopeptides; Organotechnetium Compounds; Radionuclide Imaging; Rats, Sprague-Dawley | 2015 |
Integrin-targeted delivery into cancer cells of a Pt(IV) pro-drug through conjugation to RGD-containing peptides.
Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Neoplasms; Oligopeptides; Organoplatinum Compounds; Prodrugs; Receptors, Vitronectin | 2015 |
Multifunctional calcium phosphate nanoparticles for combining near-infrared fluorescence imaging and photodynamic therapy.
Topics: Animals; Apoptosis; Calcium Phosphates; Cell Line, Tumor; Endocytosis; Female; Fluorescence; Humans; Infrared Rays; Light; Luminescent Measurements; Mice, Nude; Molecular Imaging; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Photochemotherapy; Scattering, Radiation; Tissue Distribution | 2015 |
Conjugated polymer and drug co-encapsulated nanoparticles for chemo- and photo-thermal combination therapy with two-photon regulated fast drug release.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Nucleus; Combined Modality Therapy; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; HEK293 Cells; Humans; Hyperthermia, Induced; Inhibitory Concentration 50; Integrin alphaVbeta3; Lactic Acid; Lasers; Magnetic Resonance Spectroscopy; MCF-7 Cells; Microscopy, Confocal; Nanoparticles; Nanotechnology; Naphthoquinones; Neoplasms; Oligopeptides; Photochemotherapy; Photons; Polyesters; Polymers; Spectroscopy, Near-Infrared | 2015 |
Programmed co-delivery of paclitaxel and doxorubicin boosted by camouflaging with erythrocyte membrane.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Chitosan; Doxorubicin; Drug Carriers; Erythrocyte Membrane; Humans; Hydrophobic and Hydrophilic Interactions; Magnetic Fields; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Neoplasms; Oligopeptides; Paclitaxel; Polyethylene Glycols; Survival Rate; Tissue Distribution | 2015 |
Integrin-targeted pH-responsive micelles for enhanced efficiency of anticancer treatment in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Doxorubicin; Drug Delivery Systems; Endocytosis; Hep G2 Cells; Humans; Integrins; Mice; Neoplasm Proteins; Neoplasms; NIH 3T3 Cells; Oligopeptides; Propylene Glycols | 2015 |
Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates.
Topics: Animals; Cells, Cultured; Endothelial Cells; Female; Ferric Compounds; Humans; Magnetic Resonance Imaging; Mice, Inbred C57BL; Microspheres; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Protein Binding; Radiography | 2015 |
MRI-visible liposome nanovehicles for potential tumor-targeted delivery of multimodal therapies.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Contrast Media; Drug Carriers; Fluorescent Dyes; Heterocyclic Compounds; Humans; Liposomes; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Nanostructures; Neoplasms; Oligopeptides; Organometallic Compounds; Paclitaxel; Polyethylene Glycols; Radiography; Transplantation, Heterologous | 2015 |
Dendrimer-entrapped gold nanoparticles modified with RGD peptide and alpha-tocopheryl succinate enable targeted theranostics of cancer cells.
Topics: alpha-Tocopherol; Dendrimers; Gold; Metal Nanoparticles; Neoplasms; Oligopeptides; Theranostic Nanomedicine; Tomography, X-Ray Computed | 2015 |
In Vivo Cancer Dual-Targeting and Dual-Modality Imaging with Functionalized Quantum Dots.
Topics: Animals; Biocompatible Materials; Bombesin; Copper Radioisotopes; Female; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms; Nitrophenols; Oligopeptides; Peptides; Positron-Emission Tomography; Prostatic Neoplasms; Quantum Dots; Receptors, Bombesin; Semiconductors; Spectrometry, Fluorescence; Tissue Distribution | 2015 |
Integrin αvβ3 targeting activity study of different retro-inverso sequences of RGD and their potentiality in the designing of tumor targeting peptides.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Fluorescein-5-isothiocyanate; HeLa Cells; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Neoplasms; Oligopeptides; Xenograft Model Antitumor Assays | 2015 |
Rational Design of Cancer-Targeted Benzoselenadiazole by RGD Peptide Functionalization for Cancer Theranostics.
Topics: Azoles; Drug Design; Endocytosis; Humans; Neoplasms; Oligopeptides; Proton Magnetic Resonance Spectroscopy; Reactive Oxygen Species; Signal Transduction; Theranostic Nanomedicine | 2015 |
Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells.
Topics: Animals; Capsid Proteins; Cell Line, Tumor; Dependovirus; Disease Models, Animal; Genetic Therapy; Genetic Vectors; HEK293 Cells; Hepatocytes; Humans; Male; Mice; Neoplasms; Oligopeptides; Plasmids; Recombinant Proteins; Transduction, Genetic; Viral Tropism; Xenograft Model Antitumor Assays | 2016 |
New Tris(hydroxypyridinone) Bifunctional Chelators Containing Isothiocyanate Groups Provide a Versatile Platform for Rapid One-Step Labeling and PET Imaging with (68)Ga(3.).
Topics: Animals; Chelating Agents; Gallium Radioisotopes; Integrin alphaVbeta3; Isothiocyanates; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides; Positron-Emission Tomography; Pyridones; Tissue Distribution | 2016 |
RGD-conjugated two-photon absorbing near-IR emitting fluorescent probes for tumor vasculature imaging.
Topics: Animals; Carcinoma, Lewis Lung; Fluorescent Dyes; Humans; Infrared Rays; Integrins; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Nanoparticles; Neoplasms; Oligopeptides; Optical Imaging; Photons | 2015 |
Synthesis, luminescence, and anti-tumor properties of MgSiO3:Eu-DOX-DPP-RGD hollow microspheres.
Topics: Animals; Antineoplastic Agents; Cell Survival; Doxorubicin; Drug Carriers; Endocytosis; Erythrocytes; Europium; HeLa Cells; Hemolysis; Humans; Light; Mice; Microspheres; Neoplasms; Oligopeptides; Platinum; Porosity; Prodrugs; Silicon Dioxide; Transplantation, Heterologous | 2015 |
RGD mimetics γ-AApeptides and methods of use (US 20,140,004,039 A1): a patent evaluation.
Topics: Animals; Antineoplastic Agents; Drug Design; Humans; Integrin alphaVbeta3; Mice; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Patents as Topic; Positron-Emission Tomography | 2016 |
Zwitterionic nanoparticles constructed from bioreducible RAFT-ROP double head agent for shell shedding triggered intracellular drug delivery.
Topics: Animals; Betaine; Doxorubicin; Drug Delivery Systems; Drug Screening Assays, Antitumor; Female; Hep G2 Cells; Humans; Nanoparticles; Neoplasms; Oligopeptides; Polyesters; Polymethacrylic Acids; Rats; Rats, Wistar; Theranostic Nanomedicine | 2016 |
A Multi Targeting Conditionally Replicating Adenovirus Displays Enhanced Oncolysis while Maintaining Expression of Immunotherapeutic Agents.
Topics: Adenoviridae; Adenovirus E1A Proteins; Base Sequence; Cell Line, Tumor; Humans; Immunotherapy; Neoplasms; Oligopeptides; Oncolytic Virotherapy; Oncolytic Viruses; Sequence Deletion; Virus Replication | 2015 |
Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and grafting method.
Topics: Amino Acid Transport System ASC; Animals; Cell Cycle Proteins; Cell Line, Tumor; Chitosan; Female; Green Fluorescent Proteins; Humans; Ligands; Mice, Nude; Minor Histocompatibility Antigens; Molecular Structure; Nanoparticles; Neoplasms; Oligopeptides; Oncogene Proteins; Polyethylene Glycols; RNA, Small Interfering | 2016 |
Tumor Angiogenesis Targeted Radiosensitization Therapy Using Gold Nanoprobes Guided by MRI/SPECT Imaging.
Topics: Animals; Cell Death; Cell Line, Tumor; Gadolinium; Gold; Humans; Immunohistochemistry; Integrin alphaVbeta3; Magnetic Resonance Imaging; Metal Nanoparticles; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Radiation Tolerance; Subcellular Fractions; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2016 |
Tumor vascular-targeted co-delivery of anti-angiogenesis and chemotherapeutic agents by mesoporous silica nanoparticle-based drug delivery system for synergetic therapy of tumor.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Drug Carriers; Drug Delivery Systems; HeLa Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Nanoparticles; Neoplasms; Oligopeptides; Silicon Dioxide; Stilbenes; Tissue Distribution; Xenograft Model Antitumor Assays | 2016 |
Dual-functionalized liposomal delivery system for solid tumors based on RGD and a pH-responsive antimicrobial peptide.
Topics: Animals; Antimicrobial Cationic Peptides; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Humans; Hydrogen-Ion Concentration; Integrin alphaVbeta3; Liposomes; MCF-7 Cells; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Neoplasms; Oligopeptides; Paclitaxel; Particle Size; Polyethylene Glycols; Tissue Distribution; Transplantation, Heterologous; Tumor Microenvironment | 2016 |
RGD and polyhistidine tumor homing peptides potentiates the action of human Maspin as an antineoplastic candidate.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Escherichia coli; Female; Gene Expression Regulation; Genes, Tumor Suppressor; Histidine; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides; Recombinant Proteins; Serpins; Xenograft Model Antitumor Assays | 2016 |
RGD-modified lipid disks as drug carriers for tumor targeted drug delivery.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Erythrocytes; Hemolysis; Humans; Lipids; Male; Melitten; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasms; Oligopeptides; Rats; Rats, Sprague-Dawley; Tissue Distribution; Xenograft Model Antitumor Assays | 2016 |
Ultra-pH-Responsive and Tumor-Penetrating Nanoplatform for Targeted siRNA Delivery with Robust Anti-Cancer Efficacy.
Topics: Cell Line, Tumor; Delayed-Action Preparations; Gene Transfer Techniques; HeLa Cells; Humans; Hydrogen-Ion Concentration; Inhibitor of Apoptosis Proteins; Nanoparticles; Neoplasms; Oligopeptides; Polyethylene Glycols; Polymers; RNA, Small Interfering; RNAi Therapeutics; Survivin | 2016 |
A ratiometric theranostic probe for tumor targeting therapy and self-therapeutic monitoring.
Topics: Animals; Chlorocebus aethiops; COS Cells; Drug Monitoring; Fluorescence Resonance Energy Transfer; Nanocapsules; Neoplasms; Neoplasms, Experimental; Oligopeptides; Photosensitizing Agents; Protoporphyrins; Reactive Oxygen Species; Theranostic Nanomedicine; Treatment Outcome | 2016 |
Doxorubicin-triggered self-assembly of native amphiphilic peptides into spherical nanoparticles.
Topics: A549 Cells; Amino Acid Motifs; Circular Dichroism; Cytosol; Delayed-Action Preparations; Doxorubicin; Drug Carriers; Flow Cytometry; HEK293 Cells; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Micelles; Microscopy, Confocal; Nanoparticles; Neoplasms; Oligopeptides; Peptides; Polymers | 2016 |
A redox-responsive mesoporous silica nanoparticle with a therapeutic peptide shell for tumor targeting synergistic therapy.
Topics: Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Doxorubicin; Drug Delivery Systems; Humans; Nanoparticles; Neoplasms; Oligopeptides; Oxidation-Reduction; Peptides; Porosity; Silicon Dioxide | 2016 |
Dendrimer-Stabilized Gold Nanostars as a Multifunctional Theranostic Nanoplatform for CT Imaging, Photothermal Therapy, and Gene Silencing of Tumors.
Topics: Animals; Cell Line, Tumor; Dendrimers; Gene Silencing; Gold; Humans; Infrared Rays; Integrin alphaVbeta3; Metal Nanoparticles; Mice; Nanostructures; Neoplasms; Oligopeptides; Phototherapy; RNA, Small Interfering; Theranostic Nanomedicine; Vascular Endothelial Growth Factor A | 2016 |
Enhancing PET Signal at Target Tissue in Vivo: Dendritic and Multimeric Tris(hydroxypyridinone) Conjugates for Molecular Imaging of α
Topics: Animals; Arthritis, Rheumatoid; Chelating Agents; Female; Gallium Radioisotopes; Integrin alphaVbeta3; Joints; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms; Oligopeptides; Positron-Emission Tomography; Pyridines; Tissue Distribution | 2017 |
Foot-and-mouth disease virus-like particles as integrin-based drug delivery system achieve targeting anti-tumor efficacy.
Topics: Animals; Antibiotics, Antineoplastic; Cats; Cell Line; Cell Survival; Doxorubicin; Drug Carriers; Drug Delivery Systems; Foot-and-Mouth Disease Virus; HeLa Cells; Humans; Integrins; Male; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides | 2017 |
Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy.
Topics: Animals; Antineoplastic Agents; Biomimetic Materials; Blood Vessels; Cell Line, Tumor; Cell Survival; Cells, Cultured; Dextrans; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells; Humans; Mice, Nude; Microtubules; Nanostructures; Neoplasm Transplantation; Neoplasms; Oligopeptides; Paclitaxel; Tumor Necrosis Factor-alpha | 2017 |
Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Endothelium; Integrin alphaVbeta3; Kidney Neoplasms; Mice; Nanoparticles; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2008 |
Multifunctional polymeric micelles for enhanced intracellular delivery of doxorubicin to metastatic cancer cells.
Topics: Antibiotics, Antineoplastic; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Hydrolysis; Magnetic Resonance Spectroscopy; Micelles; Neoplasm Metastasis; Neoplasms; Oligopeptides; Polymers; Solubility | 2008 |
RGD-IL-24, a novel tumor-targeted fusion cytokine: expression, purification and functional evaluation.
Topics: Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Female; Humans; Interleukins; Neoplasms; Oligopeptides; Recombinant Fusion Proteins | 2009 |
Molecular imaging of tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots.
Topics: Animals; Chickens; Chorioallantoic Membrane; Diagnostic Imaging; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Quantum Dots | 2009 |
Use of a novel Arg-Gly-Asp radioligand, 18F-AH111585, to determine changes in tumor vascularity after antitumor therapy.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; Carcinoma, Non-Small-Cell Lung; Dose-Response Relationship, Drug; Mice; Neoplasms; Oligopeptides; Paclitaxel; Peptides; Polyethylene Glycols; Positron-Emission Tomography; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Tissue Distribution; Triazoles | 2009 |
A novel method for direct site-specific radiolabeling of peptides using [18F]FDG.
Topics: Animals; Cell Line, Tumor; Fluorodeoxyglucose F18; Humans; Integrin alphaVbeta3; Mice; Mice, Nude; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals | 2009 |
Noninvasive imaging of tumor integrin expression using (18)F-labeled RGD dimer peptide with PEG (4) linkers.
Topics: Animals; Azides; Dimerization; Female; Gene Expression Regulation, Neoplastic; Glutamic Acid; Humans; Integrin alphaVbeta3; Iodine Radioisotopes; Isotope Labeling; Mice; Neoplasms; Oligopeptides; Polyethylene Glycols; Positron-Emission Tomography; Radiochemistry; Tissue Distribution | 2009 |
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Humans; Integrin alphaVbeta3; Lung Neoplasms; Melanoma, Experimental; Mice; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Vascular Endothelial Growth Factor A | 2009 |
The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor.
Topics: Angiogenic Proteins; Animals; Antibodies, Monoclonal; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chickens; Chorioallantoic Membrane; Collagen; Drug Combinations; Endothelial Cells; Female; Fibronectins; Humans; Laminin; Neoplasms; Neovascularization, Pathologic; Neural Cell Adhesion Molecule L1; Oligopeptides; Ovarian Neoplasms; Protein Structure, Tertiary; Proteoglycans; Repetitive Sequences, Amino Acid; Solubility; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery.
Topics: Cell Line, Tumor; Ferric Compounds; Fluorescent Dyes; Gene Knockdown Techniques; Gene Silencing; Humans; Magnetic Resonance Imaging; Magnetics; Nanoparticles; Neoplasms; Oligopeptides; RNA, Small Interfering; Spectrometry, Fluorescence; Transfection | 2009 |
99mTcO(MAG2-3G3-dimer): a new integrin alpha(v)beta(3)-targeted SPECT radiotracer with high tumor uptake and favorable pharmacokinetics.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Female; Humans; Integrin alphaVbeta3; Mice; Neoplasms; Oligopeptides; Organotechnetium Compounds; Radioactive Tracers; Radiochemistry; Substrate Specificity; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Tumor Burden | 2009 |
Replacement of adenovirus type 5 fiber shaft heparan sulfate proteoglycan-binding domain with RGD for improved tumor infectivity and targeting.
Topics: Adenoviridae; Animals; Cell Line, Tumor; Genetic Vectors; Heparan Sulfate Proteoglycans; Humans; Liver; Luciferases; Mice; Neoplasms; Oligopeptides; Protein Structure, Tertiary; Recombination, Genetic; Tissue Distribution; Transduction, Genetic | 2009 |
Imparting multivalency to a bifunctional chelator: a scaffold design for targeted PET imaging probes.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Drug Design; Humans; Integrin alphaVbeta3; Mice; Neoplasms; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography; Transplantation, Heterologous | 2009 |
Triblock copolymer coated iron oxide nanoparticle conjugate for tumor integrin targeting.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Ferric Compounds; Fluorescent Dyes; Glioblastoma; Humans; Integrins; Materials Testing; Mice; Molecular Structure; Nanoparticles; Neoplasms; Oligopeptides; Polymers; Surface Properties; Tissue Distribution; Transplantation, Heterologous | 2009 |
Control of hypoxia-induced tumor cell adhesion by cytophilic human catalase.
Topics: Animals; Catalase; Cats; Cell Adhesion; Cell Hypoxia; Endothelium, Vascular; Humans; Hydrogen Peroxide; Hypoxia-Inducible Factor 1; Mice; Neoplasms; NF-kappa B; Oligopeptides; Reactive Oxygen Species; Recombinant Fusion Proteins | 2009 |
Tissue-penetrating delivery of compounds and nanoparticles into tumors.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Integrins; Mice; Mice, Nude; Nanoparticles; Neoplasms; Neoplasms, Experimental; Neuropilin-1; Oligopeptides | 2009 |
Radiolabeling RGD peptide and preliminary biodistribution evaluation in mice bearing S180 tumors.
Topics: Amino Acid Sequence; Animals; Cattle; Integrin alphaVbeta3; Mice; Neoplasms; Oligopeptides; Protein Stability; Radioisotopes; Rhenium; Tissue Distribution | 2010 |
Optical imaging of integrin alphavbeta3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers.
Topics: Analysis of Variance; Animals; Cell Line, Tumor; Ethylene Glycol; Female; Fluorescent Antibody Technique; Fluorometry; Humans; Indoles; Integrin alphaVbeta3; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Oligopeptides; Spectroscopy, Near-Infrared; Whole Body Imaging | 2010 |
Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Biomimetic Materials; Cell Adhesion; Cell Line, Tumor; Cell Transformation, Neoplastic; Contrast Media; Drug Design; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; Integrins; Mice; Microbubbles; Molecular Sequence Data; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Reproducibility of Results; Ultrasonography | 2010 |
Tumor uptake of the RGD dimeric probe (99m)Tc-G3-2P4-RGD2 is correlated with integrin αvβ3 expressed on both tumor cells and neovasculature.
Topics: Animals; Dimerization; Female; Fluorescent Dyes; HT29 Cells; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organotechnetium Compounds; Peptides, Cyclic; Tissue Distribution; Tumor Cells, Cultured | 2010 |
Photothermal effects of supramolecularly assembled gold nanoparticles for the targeted treatment of cancer cells.
Topics: Cell Line, Tumor; Fluorescent Dyes; Gold; Humans; Metal Nanoparticles; Microscopy, Fluorescence; Neoplasms; Oligopeptides; Photosensitizing Agents | 2010 |
Tissue-factor fusion proteins induce occlusion of tumor vessels.
Topics: Animals; Antineoplastic Agents; Blood Vessels; Escherichia coli; Gene Expression; Humans; Male; Mice; Mice, Nude; Neoplasms; Oligopeptides; Recombinant Fusion Proteins; Thromboplastin | 2010 |
Tumor-penetrating peptides: a shift from magic bullets to magic guns.
Topics: Drug Delivery Systems; Humans; Integrins; Neoplasms; Oligopeptides; Protein Binding; Translational Research, Biomedical | 2010 |
Core-shell nanosized assemblies mediated by the alpha-beta cyclodextrin dimer with a tumor-triggered targeting property.
Topics: alpha-Cyclodextrins; beta-Cyclodextrins; Cell Survival; Dimerization; Doxorubicin; Drug Carriers; Fluorescein-5-isothiocyanate; Fluorescent Dyes; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Micelles; Nanoshells; Neoplasms; Oligopeptides; Polyethylene Glycols; Rhodamines | 2010 |
RGD-cyclam conjugate: synthesis and potential application for positron emission tomography.
Topics: Animals; Copper Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Mice; Mice, Nude; Neoplasms; Oligopeptides; Positron-Emission Tomography | 2010 |
Dynamic visualization of RGD-quantum dot binding to tumor neovasculature and extravasation in multiple living mouse models using intravital microscopy.
Topics: Animals; Cell Line, Tumor; Humans; Mice; Mice, Nude; Microscopy; Nanoparticles; Nanotechnology; Neoplasms; Oligopeptides; Quantum Dots | 2010 |
MicroPET imaging of integrin αvβ3 expressing tumors using 89Zr-RGD peptides.
Topics: Animals; Binding, Competitive; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Ligands; Mice; Mice, Nude; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Tissue Distribution; Zirconium | 2011 |
Two ⁹⁰Y-labeled multimeric RGD peptides RGD4 and 3PRGD2 for integrin targeted radionuclide therapy.
Topics: Animals; Dimerization; Female; Fluorescent Antibody Technique; Humans; Indium Radioisotopes; Integrin alphaVbeta3; Maximum Tolerated Dose; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides; Radiopharmaceuticals; Substrate Specificity; Technetium; Tissue Distribution; Tomography, Emission-Computed; Tumor Cells, Cultured; Xenograft Model Antitumor Assays; Yttrium Radioisotopes | 2011 |
Synthesis and evaluation of new iRGD peptide analogs for tumor optical imaging.
Topics: Amino Acid Sequence; Animals; Fluorescent Dyes; Heterocyclic Compounds, 1-Ring; Integrin alphaVbeta3; Mice; Mice, Nude; Neoplasms; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography; Transplantation, Heterologous | 2011 |
Solid phase synthesis, radiolabeling and biological evaluation of a (99m) Tc-labeled α(V)β(3) tripeptide (RGD) conjugated to DOTA as a tumor imaging agent.
Topics: Animals; Cell Line, Tumor; Cell Survival; Drug Stability; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria; Neoplasms; Oligopeptides; Quality Control; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Technetium | 2011 |
Integrin-assisted drug delivery of nano-scaled polymer therapeutics bearing paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cathepsin B; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Humans; Integrins; Mice; Mice, Inbred BALB C; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Paclitaxel; Polyglutamic Acid; Rats; Rats, Wistar | 2011 |
Clustered Arg-Gly-Asp peptides enhances tumor targeting of nonviral vectors.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Genetic Vectors; HeLa Cells; Humans; Mice; Molecular Sequence Data; Neoplasms; NIH 3T3 Cells; Oligopeptides; Positron-Emission Tomography; Structure-Activity Relationship | 2011 |
Macrocyclic chelator assembled RGD multimers for tumor targeting.
Topics: Animals; Chelating Agents; Diagnostic Imaging; Drug Delivery Systems; Heterocyclic Compounds, 1-Ring; Macrocyclic Compounds; Mice; Molecular Structure; Neoplasms; Oligopeptides | 2011 |
Noninvasive visualization and quantification of tumor αVβ3 integrin expression using a novel positron emission tomography probe, 64Cu-cyclam-RAFT-c(-RGDfK-)4.
Topics: Animals; Biological Transport; Cell Line, Tumor; Coordination Complexes; Drug Stability; Female; Gene Expression Regulation, Neoplastic; Half-Life; HEK293 Cells; Humans; Integrin alphaVbeta3; Mice; Molecular Imaging; Neoplasms; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography | 2011 |
Active targeting of RGD-conjugated bioreducible polymer for delivery of oncolytic adenovirus expressing shRNA against IL-8 mRNA.
Topics: Adenoviridae; Apoptosis; Cell Line, Tumor; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrins; Interleukin-8; Materials Testing; Molecular Structure; Neoplasms; Oligopeptides; Oncolytic Viruses; Particle Size; Polymers; Receptors, Virus; RNA, Small Interfering; Vascular Endothelial Growth Factor A | 2011 |
RGD-modified angiogenesis inhibitor HM-3 dose: dual function during cancer treatment.
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; Oligopeptides; Organ Culture Techniques; Peptides; Proto-Oncogene Proteins c-akt | 2011 |
SPIO-RGD nanoparticles as a molecular targeting probe for imaging tumor angiogenesis using synchrotron radiation.
Topics: Animals; Cell Line, Tumor; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Probes; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Synchrotrons | 2011 |
Novel integrin-targeted binding-triggered drug delivery system for methotrexate.
Topics: Amino Acid Sequence; Antimetabolites, Antineoplastic; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Methotrexate; Models, Molecular; Neoplasms; Oligopeptides; Prodrugs; Protein Binding; Protein Conformation | 2011 |
Improved systemic antitumor therapy with oncolytic adenoviruses by replacing the fiber shaft HSG-binding domain with RGD.
Topics: Adenoviridae; Animals; Binding Sites; Cell Line, Tumor; Gene Transfer Techniques; Genetic Vectors; Heparitin Sulfate; Mice; Mice, Inbred BALB C; Neoplasms; Oligopeptides; Oncolytic Virotherapy; Receptors, Cell Surface | 2012 |
Magnetic resonance imaging contrast agent: cRGD-ferric oxide nanometer particle and its role in the diagnosis of tumor.
Topics: Animals; Cell Line, Tumor; Contrast Media; Ferric Compounds; Humans; Magnetic Resonance Imaging; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides | 2011 |
Photocontrolled DNA binding of a receptor-targeted organometallic ruthenium(II) complex.
Topics: Antineoplastic Agents; Binding Sites; DNA; Drug Delivery Systems; Humans; Neoplasms; Octreotide; Oligopeptides; Organometallic Compounds; Photochemical Processes; Ruthenium | 2011 |
Cancer-targeted optical imaging with fluorescent zinc oxide nanowires.
Topics: Biocompatible Materials; Cell Line, Tumor; Humans; Integrin alphaVbeta3; Metal Nanoparticles; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Models, Chemical; Nanowires; Neoplasms; Oligopeptides; Optics and Photonics; Solubility; Zinc Oxide | 2011 |
Comparison study of [18F]FAl-NOTA-PRGD2, [18F]FPPRGD2, and [68Ga]Ga-NOTA-PRGD2 for PET imaging of U87MG tumors in mice.
Topics: Animals; Cell Line, Tumor; Fluorine Radioisotopes; Gallium Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Mice; Neoplasms; Oligopeptides; Positron-Emission Tomography | 2011 |
Influence of side chain length on fluorescence intensity of ROMP-based polymeric nanoparticles and their tumor specificity in in-vivo tumor imaging.
Topics: Animals; Diagnostic Imaging; Fluorescence; Fluorescent Dyes; Folic Acid; Glucosamine; Mice; Nanoparticles; Neoplasms; Oligopeptides; Polymerization; Polymers | 2011 |
N-Succinimidyl 4-[(18)F]-fluoromethylbenzoate-labeled dimeric RGD peptide for imaging tumor integrin expression.
Topics: Amino Acid Sequence; Animals; Benzoates; Cell Line, Tumor; Female; Fluorine Radioisotopes; Integrin alphaVbeta3; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Staining and Labeling; Succinimides; Tissue Distribution | 2012 |
Enhanced apoptosis-inducing function of MDA-7/IL-24 RGD mutant via the increased adhesion to tumor cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Adhesion; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; HeLa Cells; Hep G2 Cells; Humans; Integrin alpha5; Integrin beta3; Interleukins; Mutation; Neoplasm Proteins; Neoplasms; Oligopeptides | 2012 |
In vivo pharmacokinetics, immunogenicity and mechanism of PEGylated antitumor polypeptide.
Topics: Animals; Antibodies; Antineoplastic Agents; Area Under Curve; Cell Line, Tumor; Endostatins; Female; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; Male; Mice; Mice, Inbred BALB C; Necrosis; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Polyethylene Glycols; Protein Binding; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2012 |
Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles.
Topics: Animals; Antineoplastic Agents; Apoptosis; Drug Delivery Systems; Endothelium, Vascular; HeLa Cells; Humans; In Vitro Techniques; Lactic Acid; Male; Mice; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Oligopeptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
TumorHoPe: a database of tumor homing peptides.
Topics: Carrier Proteins; Databases, Protein; Humans; Information Storage and Retrieval; Neoplasm Proteins; Neoplasms; Oligopeptides; Peptides; Software | 2012 |
Direct fluorescence monitoring of the delivery and cellular uptake of a cancer-targeted RGD peptide-appended naphthalimide theragnostic prodrug.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Humans; Microscopy, Confocal; Naphthalimides; Neoplasms; Oligopeptides; Prodrugs | 2012 |
The dual role of fibulins in tumorigenesis.
Topics: ADAM Proteins; ADAMTS1 Protein; Animals; Calcium-Binding Proteins; Cell Transformation, Neoplastic; Elastic Tissue; Elastin; Extracellular Matrix; Extracellular Matrix Proteins; Gene Silencing; Humans; Mice; Mice, Knockout; Microfibrils; Neoplasm Proteins; Neoplasms; Oligopeptides; Protein Isoforms | 2012 |
Near-infrared fluorescent divalent RGD ligand for integrin αvβ₃-targeted optical imaging.
Topics: Animals; Carbocyanines; Cell Line, Tumor; Fluorescent Dyes; Humans; Integrin alphaVbeta3; Mice; Mice, Nude; Neoplasms; Oligopeptides; Optical Imaging | 2012 |
A rapid and convenient method to enhance transgenic expression in target cells.
Topics: Cell Line, Tumor; CREB-Binding Protein; Gene Expression; Gene Targeting; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Integrin alphaVbeta3; Neoplasm Proteins; Neoplasms; NF-kappa B; Oligopeptides; Polyethyleneimine; Response Elements; Transfection | 2012 |
Fusion of [(18)F]FDG PET with fluorescence diffuse optical tomography to improve validation of probes and tumor imaging.
Topics: Animals; Cathepsins; Cell Line, Tumor; Diffusion; Fluorescent Dyes; Fluorodeoxyglucose F18; Humans; Mice; Molecular Probes; Neoplasms; Oligopeptides; Positron-Emission Tomography; Reproducibility of Results; Tissue Distribution; Tomography, Optical | 2013 |
Small molecule fluorophore and copolymer RGD peptide conjugates for ex vivo two-photon fluorescence tumor vasculature imaging.
Topics: Animals; Carcinoma, Lewis Lung; Cell Line, Tumor; Fluorescent Dyes; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Microscopy, Fluorescence; Neoplasms; Oligopeptides | 2012 |
Discovery of novel integrin ligands from combinatorial libraries using a multiplex "beads on a bead" approach.
Topics: Biotin; Biotinylation; Cell Adhesion; Cell Line, Tumor; Collagen; Combinatorial Chemistry Techniques; Cytological Techniques; Drug Combinations; Endothelial Cells; Humans; Integrin alphaVbeta3; Laminin; Ligands; Magnetics; Microscopy, Fluorescence; Neoplasms; Oligopeptides; Peptide Library; Peptides; Proteoglycans | 2012 |
Endothelial cells internalize and degrade RGD-modified proteins developed for tumor vasculature targeting.
Topics: Cells, Cultured; Dose-Response Relationship, Drug; Drug Delivery Systems; Endothelium, Vascular; Humans; Neoplasms; Oligopeptides | 2002 |
The presence of the adenovirus E3 region improves the oncolytic potency of conditionally replicative adenoviruses.
Topics: Adenoviridae; Adenovirus E3 Proteins; Animals; Female; Gentian Violet; Humans; Mice; Mice, Nude; Models, Genetic; Neoplasm Transplantation; Neoplasms; Oligopeptides; Plasmids; Spectrophotometry; Time Factors; Tumor Cells, Cultured | 2002 |
Synthesis of RGD containing peptides and their bioactivities.
Topics: Blood Platelets; Cell Aggregation; In Vitro Techniques; Neoplasm Invasiveness; Neoplasms; Oligopeptides; Peptides; Platelet Aggregation | 2002 |
Crystal structure of trimestatin, a disintegrin containing a cell adhesion recognition motif RGD.
Topics: Amino Acid Motifs; Amino Acid Sequence; Angiogenesis Inhibitors; Antineoplastic Agents; Asparagine; Aspartic Acid; Blood Platelets; Cell Adhesion; Crystallography, X-Ray; Disintegrins; Integrin alphaVbeta3; Integrins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Neoplasms; Oligopeptides; Platelet Aggregation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Snake Venoms; Tryptophan | 2003 |
Radiolabeled RGD-DTPA-Tyr3-octreotate for receptor-targeted radionuclide therapy.
Topics: Animals; Cell Line, Tumor; Indium Radioisotopes; Neoplasms; Oligopeptides; Pentetic Acid; Peptides, Cyclic; Rats; Receptors, Somatostatin; Sensitivity and Specificity; Tissue Distribution | 2004 |
Targeting liposomes to tumor endothelial cells for neutron capture therapy.
Topics: Boron; Boron Neutron Capture Therapy; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA, Neoplasm; Endothelium, Vascular; Gamma Rays; Humans; Isotopes; Liposomes; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2004 |
RGD-modified anti-CD3 antibodies redirect cytolytic capacity of cytotoxic T lymphocytes toward alphavbeta3-expressing endothelial cells.
Topics: Antibodies; CD3 Complex; Endothelial Cells; Humans; Immunotherapy; Integrin alphaVbeta3; Leukocytes, Mononuclear; Neoplasms; Oligopeptides; T-Lymphocytes, Cytotoxic | 2004 |
CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells.
Topics: Animals; Antigens, CD; Cell Adhesion; Chondroitin Sulfates; Endothelium, Vascular; Epidermal Growth Factor; HT29 Cells; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; Membrane Glycoproteins; Mice; Neoplasms; Neovascularization, Physiologic; NIH 3T3 Cells; Oligopeptides; Phenotype; Protein Structure, Tertiary; Rats; Receptors, G-Protein-Coupled; Umbilical Veins | 2005 |
Radiolabeled RGD peptides move beyond cancer: PET imaging of delayed-type hypersensitivity reaction.
Topics: Animals; Humans; Hypersensitivity, Delayed; Image Enhancement; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals | 2005 |
Liposomalized oligopeptides in cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Line; Drug Carriers; Humans; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Structure; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2005 |
AdEasy-based cloning system to generate tropism expanded replicating adenoviruses expressing transgenes late in the viral life cycle.
Topics: Adenoviridae; Adenoviridae Infections; Adenovirus E1 Proteins; Adenovirus E3 Proteins; Capsid Proteins; Cloning, Molecular; Gene Expression; Genetic Engineering; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Neoplasms; Oligopeptides; Transgenes; Tropism; Virus Replication | 2005 |
Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression.
Topics: Animals; Carbocyanines; Fluorometry; Integrins; Ligands; Mice; Mice, Nude; Microscopy, Fluorescence; Molecular Probe Techniques; Neoplasms; Oligopeptides; Peptides, Cyclic; Snake Venoms; Spectrophotometry; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2005 |
New multifunctional molecular conjugate vector for targeting, imaging, and therapy of tumors.
Topics: Animals; Binding, Competitive; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Separation; Dose-Response Relationship, Drug; Endosomes; Female; Flow Cytometry; Genetic Therapy; Genetic Vectors; Humans; Immunohistochemistry; Infusions, Intravenous; Integrin alphaVbeta3; Ligands; Mice; Mice, Nude; Models, Chemical; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Oligopeptides; Ovarian Neoplasms; Peptides; Peptides, Cyclic; Polymers; Stereoisomerism; Vitronectin | 2005 |
Study of the labeling of two novel RGD-peptidic derivatives with the precursor [99mTc(H2O)3(CO)3]+ and evaluation for early angiogenesis detection in cancer.
Topics: Animals; Female; Isotope Labeling; Mice; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Technetium Compounds; Tissue Distribution | 2006 |
MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle.
Topics: Animals; Binding, Competitive; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Integrin alphaVbeta3; Lipids; Liposomes; Magnetic Resonance Imaging; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Nanostructures; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Platelet Endothelial Cell Adhesion Molecule-1; Umbilical Veins | 2005 |
Tumor angiogenic vasculature targeting with PAMAM dendrimer-RGD conjugates.
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Dendrimers; Drug Delivery Systems; Humans; Integrins; Mice; Molecular Structure; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Polyamines | 2005 |
Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries.
Topics: Amino Acid Motifs; Amino Acid Sequence; Cell Line, Tumor; Cell Membrane; Cluster Analysis; Combinatorial Chemistry Techniques; ErbB Receptors; Humans; Ligands; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Oligopeptides; Peptide Library; Peptides; Reproducibility of Results | 2006 |
Non-cytotoxic cobra cardiotoxin A5 binds to alpha(v)beta3 integrin and inhibits bone resorption. Identification of cardiotoxins as non-RGD integrin-binding proteins of the Ly-6 family.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Bone Resorption; Cattle; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Cobra Cardiotoxin Proteins; Dose-Response Relationship, Drug; Elapidae; Endothelial Cells; Glycoproteins; Inflammation; Integrin alphaVbeta3; Integrins; Ligands; Mice; Microscopy, Electron, Scanning; Molecular Sequence Data; Necrosis; Neoplasms; Oligopeptides; Osteoclasts; Protein Binding; Protein Structure, Secondary; Pulmonary Artery; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Time Factors | 2006 |
PET-based human dosimetry of 18F-galacto-RGD, a new radiotracer for imaging alpha v beta3 expression.
Topics: Adult; Aged; Aged, 80 and over; Female; Fluorodeoxyglucose F18; Humans; Integrin alphaVbeta3; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Oligopeptides; Positron-Emission Tomography; Radiometry; Radiopharmaceuticals | 2006 |
Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.
Topics: Anoikis; Apoptosis; Benzocycloheptenes; Cell Culture Techniques; Cell Death; Endothelium, Vascular; Fetal Blood; gamma-Aminobutyric Acid; Humans; Integrin alphaVbeta3; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Umbilical Veins; Vitronectin | 2006 |
Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems.
Topics: Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Doxorubicin; Drug Delivery Systems; Ferric Compounds; Humans; Hydrogen-Ion Concentration; Integrin alphaVbeta3; Ligands; Magnetic Resonance Imaging; Micelles; Nanoparticles; Neoplasms; Oligopeptides; Polymers; Sensitivity and Specificity; Structure-Activity Relationship; Surface Properties | 2006 |
Inhibition of cancer cell adhesion by heterochiral Pro-containing RGD mimetics.
Topics: Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Fibronectins; Humans; Inhibitory Concentration 50; Molecular Mimicry; Molecular Structure; Neoplasms; Oligopeptides; Peptide Library; Proline; Protein Conformation; Structure-Activity Relationship | 2007 |
Selective tumor cell targeting using low-affinity, multivalent interactions.
Topics: Antineoplastic Agents; Cell Line, Tumor; Complement System Proteins; Disaccharides; Doxorubicin; Drug Design; Humans; Integrin alphaVbeta3; Molecular Weight; Neoplasms; Oligopeptides | 2007 |
Methods for delivery of adenoviral vectors to tumor vasculature.
Topics: Adenoviridae; Animals; BALB 3T3 Cells; Flucytosine; Fluorescent Antibody Technique; Gene Transfer Techniques; Genetic Vectors; Green Fluorescent Proteins; Humans; Hydroxyethyl Starch Derivatives; Injections, Intraperitoneal; Injections, Intravenous; Liver; Luciferases; Mice; Mice, Nude; Neoplasms; Oligopeptides; Skin; Spheroids, Cellular; Tumor Cells, Cultured | 2007 |
High-yield expression, purification and characterization of tumor-targeted IFN-alpha2a.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Movement; Chromatography, High Pressure Liquid; Endothelial Cells; Epithelial Cells; Escherichia coli; Gene Expression; Humans; Interferon-alpha; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Confocal; Neoplasms; Oligopeptides; Recombinant Fusion Proteins; Xenograft Model Antitumor Assays | 2007 |
Comparison of in vitro and in vivo properties of [99mTc]cRGD peptides labeled using different novel Tc-cores.
Topics: Animals; Binding Sites; Isotope Labeling; Metabolic Clearance Rate; Mice; Neoplasms; Oligopeptides; Organ Specificity; Protein Binding; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Tissue Distribution | 2007 |
Purification and characterization of RGD tumor-homing peptide conjugated human tumor necrosis factor alpha over-expressed in Escherichia coli.
Topics: Animals; Cell Adhesion; Chromatography, Affinity; Endopeptidases; Enteropeptidase; Escherichia coli; Gene Expression; Histidine; Humans; Mice; Neoplasms; Oligopeptides; Recombinant Fusion Proteins; Solubility; Spectrometry, Mass, Electrospray Ionization; Tumor Necrosis Factor-alpha | 2007 |
Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature.
Topics: Amino Acid Motifs; Animals; Cattle; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Inhibitory Concentration 50; Integrin alphaV; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organometallic Compounds; Peptides; Platinum | 2008 |
Preparation of peptide-conjugated quantum dots for tumor vasculature-targeted imaging.
Topics: Biomarkers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Humans; Iodine Radioisotopes; Neoplasms; Oligopeptides; Quantum Dots; Spectrometry, Fluorescence; Spectroscopy, Near-Infrared | 2008 |
Enhancement of antitumor properties of TRAIL by targeted delivery to the tumor neovasculature.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fas-Associated Death Domain Protein; Female; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Skin; Survival Rate; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Starving tumors.
Topics: Animals; Antibodies, Monoclonal; Chick Embryo; Humans; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Cytoadhesin; Receptors, Vitronectin | 1995 |
Peptides in cell adhesion research.
Topics: Amino Acid Sequence; Animals; Bacteriophages; Base Sequence; Binding Sites; Cell Adhesion; Cell Adhesion Molecules; Chromatography, Affinity; Fibronectins; Genetic Vectors; Humans; Integrins; Laminin; Molecular Sequence Data; Neoplasms; Oligopeptides; Peptides | 1994 |
Napsins: new human aspartic proteinases. Distinction between two closely related genes.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Base Sequence; Cell Line; Enzyme Precursors; Glycosylation; HeLa Cells; Humans; Kidney; Lung; Mice; Molecular Sequence Data; Neoplasms; Oligopeptides; Organ Specificity; Pepsinogen A; Protein Biosynthesis; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Swine; Tumor Cells, Cultured | 1998 |
Evaluation of a radiolabelled cyclic DTPA-RGD analogue for tumour imaging and radionuclide therapy.
Topics: Animals; Antineoplastic Agents; Autoradiography; Chromatography, High Pressure Liquid; Humans; Immunohistochemistry; Indium Radioisotopes; Iodine Radioisotopes; Neoplasms; Oligopeptides; Pentetic Acid; Peptides, Cyclic; Radionuclide Imaging; Radiopharmaceuticals; Receptors, Vitronectin | 2000 |
Highly efficient transduction of endothelial cells by targeted artificial virus-like particles.
Topics: Antineoplastic Agents; Endothelium, Vascular; Gene Targeting; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrins; Liposomes; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Polyethyleneimine; Transduction, Genetic | 2001 |