arginyl-glycyl-aspartic acid has been researched along with Disease Models, Animal in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.32) | 18.7374 |
| 1990's | 5 (6.58) | 18.2507 |
| 2000's | 20 (26.32) | 29.6817 |
| 2010's | 47 (61.84) | 24.3611 |
| 2020's | 3 (3.95) | 2.80 |
| Authors | Studies |
|---|---|
| Balasse, L; Blot-Chabaud, M; Brige, P; Dignat-George, F; Fernandez, S; Garrigue, P; Guillet, B; Hache, G; Hubert, F; Moyon, A; Nail, V; Rochais, F | 1 |
| Barksby, BS; Barnes, R; Barrett, JW; Barrett, TN; Borthwick, LA; Burgoyne, RA; Fisher, AJ; Gower, E; Hatley, RJD; Jenkins, RG; John, AE; Luckett, JC; Macdonald, SJF; Man, Y; Marshall, RP; Morrison, VS; Procopiou, PA; Pun, KT; Roper, JA; Slack, RJ; Wilkinson, AL | 1 |
| Hu, D; Li, K; Li, Y; Li, Z; Lu, SB; Sheng, Z; Wang, S; Zha, M | 1 |
| Harashima, H; Sakurai, Y; Yamamoto, S | 1 |
| Merabtene, F; Nataf, V; Prignon, A; Provost, C; Rozenblum-Beddok, L; Talbot, JN | 1 |
| Cohen, N; Costin, A; Currie, PD; Hersey, L; Joshi, V; Li, M; Manneken, JD; McKaige, EA; Miles, LB; Siegel, A; Sonntag, C; Wood, AJ | 1 |
| Chung, JK; Eo, JS; Jeong, JM; Kang, KW; Lee, DS; Lee, S; Lee, YS; Paeng, JC | 1 |
| Ge, H; Guan, L; Liu, H; Liu, P; Luo, X; Ni, S; Qi, D; Sun, Y; Tian, P; Xiao, N; Xiong, Y; Yin, X | 1 |
| Dixon, KA; Ensor, J; Gupta, S; Jackson, J; Li, C; Lu, W; Miller, J; Nazario, J; Shaw, C; Tian, M; Wright, K; Xiong, C; Zhang, R | 1 |
| Chang, E; Chin, FT; Dalman, RL; Gambhir, SS; James, ML; Kitagawa, T; Kosuge, H; McConnell, MV; Shen, B; Yamamoto, T | 1 |
| Kotra, S; Kumar, A; Mayuren, C; Pulicherla, KK; Rao, KR | 1 |
| Liu, YL; Wang, JL; Wang, ZH; Xi, Y; Zhang, Q | 1 |
| Akashi, Y; Enomoto, T; Hashimoto, S; Kurokawa, T; Miyamoto, R; Oda, T; Ohara, Y; Ohkohchi, N; Satake, M; Yamada, K | 1 |
| Hu, J; Li, W; Liu, Q; Liu, X; Shen, H; Xia, X; Xie, P; Xu, H; Yuan, D; Yuan, S | 1 |
| Berman, DS; Chen, G; Gangadharmath, UB; Gomez, LF; Gorodny, N; Kolb, HC; Mu, F; Su, H; Szardenings, K; Tamarappoo, BK; Walsh, JC | 1 |
| An, L; Du, J; Hu, H; Li, F; Shi, H; Wang, L; Wei, J; Wu, D; Yang, H; Yang, S | 1 |
| Joner, M; Kapp, TG; Kessler, H; Laufer, B; Li, L; Mas-Moruno, C; Neubauer, S; Rechenmacher, F; Steigerwald, K | 1 |
| Graham, A; Holbert, J; Nothnick, WB; Weiss, MJ | 1 |
| Barnhart, TE; Cai, W; Chakravarty, R; Hernandez, R; Hong, H; Valdovinos, HF; Yang, Y | 1 |
| Chen, Z; Ding, X; Jin, S; Li, Q; Ren, H; Tong, Y; Wang, X; Zhao, X | 1 |
| Ai, H; Chen, S; Cheng, Z; Jiang, X; Li, X; Lu, H; Qing, H; Wei, R; Wu, C; Xu, G | 1 |
| Aslanidi, G; Colon-Cortes, Y; Ling, C; Nolasco, D; Pandya, M; Sayroo, R; Yin, Z | 1 |
| Buchpiguel, CA; Carneiro, CG; de Oliveira, ÉA; Faintuch, BL; Faria, DP; Fonoff, ET; Garcez, AT; Martinez, RCR; Moro, AM; Pagano, RL; Targino, RC | 1 |
| Ballarin, B; Coles, B; Elliott Donaghue, I; Führmann, T; Morshead, CM; Nagy, A; Shoichet, MS; Tam, RY; Tator, CH; van der Kooy, D | 1 |
| Hu, Q; Kang, LK; Wang, T; Wang, XY; Wei, HM; Wen, ZH; Xu, CM | 1 |
| Cui, Y; Li, X; Liu, H; Wang, D; Zhang, C; Zhang, Y; Zhang, Z | 1 |
| Harmsen, S; Holland, EC; Huang, R; Karabeber, H; Kircher, MF; Pitter, KL; Samii, JM | 1 |
| Choy, HE; Hong, Y; Jiang, SN; Kim, DY; Min, JH; Min, JJ; Nguyen, VH; Park, SH; Szardenings, M; Zheng, JH | 1 |
| Gu, N; Jia, Z; Ma, M; Ma, Z; Song, J; Song, L; Teng, G; Xie, J; Yan, C; Zang, F; Zhang, W; Zhang, Y | 1 |
| Dalman, RL; Douglas, T; Iida, Y; Kitagawa, T; Kosuge, H; McConnell, MV; Uchida, M | 1 |
| Ashur-Fabian, O; Gellerman, G; Gerlitz, G; Luboshits, G; Pinhasov, A; Redko, B; Segal, T; Tobi, D; Tuchinsky, H | 1 |
| Atakilit, A; Chen, C; DeGrado, W; Huang, X; Jo, H; Khalifeh-Soltani, A; Qiu, W; Ren, X; Sheppard, D; Sundaram, A | 1 |
| Adem, A; Basu, I; Claros, CS; Gorecka, J; Guha, C; Healy, N; Kabarriti, R; Liu, L; Maggi, E; Quinn, TJ; Sara, A; Scandiuzzi, L; Yuan, Z | 1 |
| Bartolomé, RA; Calviño, E; Casal, JI; Escudero-Paniagua, B; Isern de Val, S; Teixidó, J; Torres, S | 1 |
| Bhakoo, KK; Boominathan, R; Cheng, P; Goggi, JL; Ng, M; Sekar, S; Shenoy, N | 1 |
| Chang, CY; Chen, KH; Chen, ZY; Lin, FH; Liu, GS; Miyagawa, T; Tseng, CL; Wang, MC | 1 |
| Barnes, LA; Cheresh, DA; Lutu-Fuga, K; Majeti, BK; Makale, M; Murphy, EA; Weis, SM; Wrasidlo, W | 1 |
| Du, KT; Gu, Y; Lee, RJ; Mihardja, S; Sievers, RE; Yu, J | 1 |
| Ambati, BK; Edelhauser, HF; Grossniklaus, HE; Kang, SJ; Kompella, UB; Singh, SR | 1 |
| Da Violante, G; Gourlaouen, M; Hart, IR; Hodivala-Dilke, KM; Jones, DT; Jones, MC; Kostourou, V; Norman, JC; Perron-Sierra, F; Reynolds, AR; Robinson, SD; Salih, M; Saunders, G; Silva, RG; Tucker, GC; Watson, AR; Welti, JC | 1 |
| Blankesteijn, WM; Daemen, MJ; Fujimoto, A; Fujimoto, S; Hofstra, L; Isobe, S; Li, P; Lovhaug, D; Narula, J; Narula, N; Petrov, A; Pitt, B; Reutelingsperger, C; Smits, JF; van den Borne, SW; Vannan, MA; Wong, ND; Zandbergen, HR; Zannad, F | 1 |
| Busuttil, RW; Coito, AJ; Duarte, S; Fondevila, C; Shen, XD | 1 |
| García, AJ; Landázuri, N; Phelps, EA; Taylor, WR; Thulé, PM | 1 |
| Banh, A; Bouley, DM; Brustugun, OT; Cao, H; Courter, D; Denko, NC; Giaccia, A; Kong, C; Koong, AC; Kuo, P; Kwok, S; Le, QT; Vice, C | 1 |
| Chen, K; Chen, X; Cheng, Z; Gao, J; Peng, X; Xie, J; Xie, R; Yan, Y | 1 |
| Du, KT; Fang, Q; Gu, Y; Lee, RJ; Mihardja, SS; Sievers, RE; Wu, JC; Yu, J | 1 |
| Berndorff, D; Chang, E; Cheng, Z; Chin, F; Gambhir, SS; Gekeler, V; Gowrishankar, G; Liu, S; Wedgeworth, JP; Yaghoubi, S | 1 |
| Bornstein, MM; Bosshardt, DD; Buser, D; Chen, B; Jensen, SS | 1 |
| Dalman, RL; Douglas, T; Dua, MM; Iida, Y; Kitagawa, T; Kosuge, H; McConnell, MV; Uchida, M | 1 |
| Acarin, L; Castellano, B; Gonzalez, B; Gonzalez, P; Peluffo, H; Villaverde, A | 1 |
| Amann, K; Daniel, C; Haas, CS; Hartner, A; Schöcklmann, HO; Schüssler, J | 1 |
| Kompella, UB; Scheinman, RI; Trivedi, R; Vermillion, S | 1 |
| Faintuch, BL; Moro, AM; Nanda, PK; Núñez, EG; Oliveira, ÉA; Smith, CJ | 1 |
| Han, J; Kong, D; Li, D; Song, L; Wang, S; Wang, Z; Yang, Z; Zhang, J; Zhao, Q; Zheng, W; Zheng, XL | 1 |
| Chen, X; Guo, N; Huang, X; Lee, S; Lu, G; Mohamedali, KA; Niu, G; Rosenblum, MG; Swierczewska, M; Wang, AY; Xu, H; Zhang, F; Zhu, L | 1 |
| Calcagno, C; Chen, W; Deddens, LH; Dijkhuizen, RM; Fayad, ZA; Gianella, A; Griffioen, AW; Jarzyna, PA; Kann, BH; Mulder, WJ; Ramachandran, S | 1 |
| Alvarez, RD; Barnes, MN; Curiel, DT; Dmitriev, I; Han, T; Kashentseva, E; Lam, JT; Leath, CA; Wu, H | 1 |
| Bleeker, EJ; Griffioen, AW; Habets, JW; Koning, GA; Mulder, WJ; Nicolay, K; Storm, G; Strijkers, GJ; van der Schaft, DW | 1 |
| Boulanger, P; Franqueville, L; Hong, SS; Lindholm, L; Miossec, P; Toh, ML; van de Loo, F; van den Berg, W | 1 |
| Goo, SY; Han, KL; Kim, KS; Kim, SM; Kim, WH; Lee, HJ; Lee, KH; Park, DK; Park, SJ | 1 |
| Alvarez, RD; Aurigemma, R; Broadt, T; Curiel, DT; Harris, R; Makhija, S; Noker, PE; Page, JG; Polley-Nelson, J; Schweikart, K; Tian, B; Tomaszewski, J; Wang, M | 1 |
| Baudy-Floc'h, M; Bi, L; Bi, W; Cai, J; Liu, S | 1 |
| Kuppuswamy, D; McDermott, PJ; Moschella, PC; Shiraishi, H; Tuxworth, WJ; Yamane, K | 1 |
| Rozdzinski, E; Tuomanen, E | 1 |
| Gailit, J; Goligorsky, MS; Gurrath, M; Kessler, H; Magazine, H; Muller, G; Noiri, E; Sheth, D | 1 |
| Bachelet, CM; Guiso, N; Khelef, N; Vargaftig, BB | 1 |
| Blevitt, JM; Craig, WS; Harasaki, H; Helmus, MN; Jones, M; Pierschbacher, M; Tweden, KS | 1 |
| Blajchman, MA | 1 |
| Doi, R; Fujii, N; Fujimoto, K; Hosotani, R; Ida, J; Imamura, M; Kawaguchi, M; Koizumi, M; Masui, T; Nakajima, S; Ohishi, S; Toyoda, E; Tsuji, S; Tulachan, SS; Wada, M | 1 |
| Saiki, I; Sawada, S; Tsuchiya, Y; Tsukada, K | 1 |
| Lin, N; Peng, S; Wang, C; Zhao, M | 1 |
| Burke, PA; DeNardo, GL; DeNardo, SJ; Kukis, DL; Miers, LA | 1 |
| Bretzel, RG; Brownlee, M; Chavakis, E; Hammes, HP; Lin, J; Linn, T; Preissner, KT; Riecke, B | 1 |
| Banai, S; Fishbein, I; Gertz, SD; Golomb, G; Margolin, L; Perez, LS; Reich, R | 1 |
| Bunting, S; Collen, D; Imura, Y; Stassen, JM; Stockmans, F | 1 |
| Cadroy, Y; Hanson, SR; Houghten, RA | 1 |
2 review(s) available for arginyl-glycyl-aspartic acid and Disease Models, Animal
| Article | Year |
|---|---|
Adhesion of microbial pathogens to leukocyte integrins: methods to study ligand mimicry.
Topics: Amino Acid Sequence; Animals; Bacterial Adhesion; Cell Movement; Disease Models, Animal; Factor X; Humans; In Vitro Techniques; Integrins; Leukocytes; Ligands; Meningitis, Pneumococcal; Molecular Sequence Data; Oligopeptides | 1995 |
Novel platelet products, substitutes and alternatives.
Topics: Animals; Blood Platelets; Blood Preservation; Blood Substitutes; Cell Membrane; Clinical Trials as Topic; Cryopreservation; Disease Models, Animal; Dogs; Erythrocytes; Factor VIIa; Factor X; Fibrinogen; Freeze Drying; Furocoumarins; Hemorrhage; Hemostatic Techniques; Histocompatibility; Humans; Ligands; Liposomes; Microspheres; Oligopeptides; Photochemistry; Platelet Transfusion; Ultraviolet Rays | 2001 |
74 other study(ies) available for arginyl-glycyl-aspartic acid and Disease Models, Animal
| Article | Year |
|---|---|
Comparison of a New
Topics: Animals; CD146 Antigen; Disease Models, Animal; Fibrosis; Fluorodeoxyglucose F18; Gallium Radioisotopes; Integrin alphaVbeta3; Male; Mice; Myocardial Infarction; Myocardium; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals | 2021 |
Pharmacological characterisation of GSK3335103, an oral αvβ6 integrin small molecule RGD-mimetic inhibitor for the treatment of fibrotic disease.
Topics: Administration, Oral; Animals; Antifibrotic Agents; Antigens, Neoplasm; Biological Availability; Bleomycin; Cells, Cultured; Disease Models, Animal; Epithelial Cells; Humans; Integrins; Lung; Lysosomes; Male; Mice; Oligopeptides; Primary Cell Culture; Proteolysis; Pulmonary Fibrosis; Transforming Growth Factor beta | 2021 |
Targeted NIR-II emissive nanoprobes for tumor detection in mice and rabbits.
Topics: Animals; Brain; Disease Models, Animal; Fluorescent Dyes; Indocyanine Green; Mice; Nanoparticles; Neoplasms; Oligopeptides; Rabbits; Spectroscopy, Near-Infrared | 2021 |
Failure of active targeting by a cholesterol-anchored ligand and improvement by altering the lipid composition to prevent ligand desorption.
Topics: Animals; Cell Line, Tumor; Cholesterol; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Ligands; Lipids; Liposomes; Mice; Mice, Inbred BALB C; Neoplasms; Oligopeptides; Peptides; Polyethylene Glycols; RNA, Small Interfering | 2018 |
[
Topics: Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Fluorodeoxyglucose F18; Gallium Radioisotopes; Glioblastoma; Humans; Mice; Oligopeptides; Positron-Emission Tomography; Temozolomide; Tissue Distribution; Treatment Outcome; Tumor Burden | 2019 |
RGD inhibition of itgb1 ameliorates laminin-α2-deficient zebrafish fibre pathology.
Topics: Animals; Basement Membrane; Biomarkers; Collagen; Disease Models, Animal; Disease Susceptibility; Genetic Loci; Immunohistochemistry; Integrin beta1; Laminin; Mice, Knockout; Muscle Fibers, Skeletal; Muscular Dystrophies; Oligopeptides; Phenotype; Protein Stability | 2019 |
Angiogenesis imaging in myocardial infarction using 68Ga-NOTA-RGD PET: characterization and application to therapeutic efficacy monitoring in rats.
Topics: Angiogenesis Inducing Agents; Animals; Coordination Complexes; Disease Models, Animal; Female; Fibroblast Growth Factor 2; Gallium Radioisotopes; Heart; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Myocardial Infarction; Neovascularization, Physiologic; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley | 2013 |
A C-terminal fragment BIGH3 protein with an RGDRGD motif inhibits corneal neovascularization in vitro and in vivo.
Topics: Amino Acid Motifs; Angiogenesis Inhibitors; Animals; Apoptosis; Blood Vessels; Blotting, Western; Caspases; Cell Adhesion; Cell Movement; Cell Proliferation; Corneal Neovascularization; Disease Models, Animal; Extracellular Matrix Proteins; Flow Cytometry; Human Umbilical Vein Endothelial Cells; Integrin alphaVbeta3; Mutagenesis, Site-Directed; Oligopeptides; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Folding; Proto-Oncogene Proteins c-akt; Rabbits; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A | 2013 |
Tumor uptake of hollow gold nanospheres after intravenous and intra-arterial injection: PET/CT study in a rabbit VX2 liver cancer model.
Topics: Animals; Disease Models, Animal; Gold; Injections, Intra-Arterial; Injections, Intravenous; Liver Neoplasms; Nanospheres; Oligopeptides; Polyethylene Glycols; Positron-Emission Tomography; Rabbits; Tissue Distribution; Tomography, X-Ray Computed; Whole Body Imaging | 2013 |
Integrin-targeted molecular imaging of experimental abdominal aortic aneurysms by (18)F-labeled Arg-Gly-Asp positron-emission tomography.
Topics: Animals; Aortic Aneurysm, Abdominal; Diagnosis, Differential; Disease Models, Animal; Fluorodeoxyglucose F18; Immunohistochemistry; Integrin alphaVbeta3; Male; Mice; Molecular Imaging; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results | 2013 |
Evaluation of a multifunctional staphylokinase variant with thrombin inhibition and antiplatelet aggregation activities produced from salt-inducible E. coli GJ1158.
Topics: Animals; Antithrombins; Blood Coagulation; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Hirudins; Male; Metalloendopeptidases; Mice; Mice, Inbred BALB C; Oligopeptides; Partial Thromboplastin Time; Peptide Fragments; Platelet Aggregation; Platelet Aggregation Inhibitors; Prothrombin Time; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Recombinant Proteins; Sodium Chloride; Thrombin Time; Thrombosis; Time Factors | 2013 |
Combination of targeted PDT and anti-VEGF therapy for rat CNV by RGD-modified liposomal photocyanine and sorafenib.
Topics: Animals; Choroidal Neovascularization; Disease Models, Animal; Fluorescein Angiography; Fundus Oculi; Humans; Liposomes; Male; Niacinamide; Oligopeptides; Phenylurea Compounds; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Inbred BN; Receptors, Immunologic; Sorafenib; Vascular Endothelial Growth Factor A | 2013 |
Anticancer effects of gemcitabine are enhanced by co-administered iRGD peptide in murine pancreatic cancer models that overexpressed neuropilin-1.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Deoxycytidine; Disease Models, Animal; Drug Synergism; Female; Gemcitabine; Humans; Male; Mice; Middle Aged; Neuropilin-1; Oligopeptides; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Pharmacokinetics of HM-3 after intravitreal administration in mice.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Blood-Retinal Barrier; Choroid; Choroidal Neovascularization; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Intravitreal Injections; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Vitreous Body | 2014 |
Atherosclerotic plaque uptake of a novel integrin tracer ¹⁸F-Flotegatide in a mouse model of atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Biomarkers; Disease Models, Animal; Female; Fluorine Radioisotopes; Integrin alphaVbeta3; Mice; Mice, Knockout; Molecular Imaging; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity | 2014 |
Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging.
Topics: Administration, Intravenous; Animals; Cell Line, Tumor; Contrast Media; Disease Models, Animal; Drug Delivery Systems; Feces; Gadolinium DTPA; Humans; Liver; Lung; Magnetic Resonance Imaging; Male; Mice; Mice, Nude; Nanospheres; Neoplasm Transplantation; Neoplasms; Oligopeptides; Polystyrenes; Silicon Dioxide; Tissue Distribution; Ultrasonography | 2014 |
The integrin ligand c(RGDf(NMe)Nal) reduces neointimal hyperplasia in a polymer-free drug-eluting stent system.
Topics: Animals; Cell Line; Cell Proliferation; Disease Models, Animal; Drug-Eluting Stents; Hyperplasia; Immunosuppressive Agents; Integrins; Oligopeptides; Polymers; Rabbits; Snake Venoms; Wound Healing | 2014 |
miR-451 deficiency is associated with altered endometrial fibrinogen alpha chain expression and reduced endometriotic implant establishment in an experimental mouse model.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cells, Cultured; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Endometriosis; Endometrium; Female; Fibrinogen; Humans; Mice; Mice, Inbred C57BL; MicroRNAs; Molecular Sequence Data; Oligopeptides; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
(44)Sc: an attractive isotope for peptide-based PET imaging.
Topics: Amino Acid Motifs; Animals; Binding, Competitive; Calcium; Cell Line, Tumor; Disease Models, Animal; Heterocyclic Compounds, 1-Ring; Humans; Image Processing, Computer-Assisted; Inhibitory Concentration 50; Integrin alphaVbeta3; Mice; Molecular Imaging; Neoplasm Transplantation; Neoplasms; Oligopeptides; Peptides; Positron-Emission Tomography; Radioisotopes; Scandium; Tissue Distribution | 2014 |
RGD peptides protects against acute lung injury in septic mice through Wisp1-integrin β6 pathway inhibition.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Capillaries; CCN Intercellular Signaling Proteins; Disease Models, Animal; Immunoprecipitation; Integrin beta Chains; Interleukin-6; Lung; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Proto-Oncogene Proteins; Sepsis; Tumor Necrosis Factor-alpha | 2015 |
Ex-vivo biodistribution and micro-PET/CT imaging of 18F-FDG, 18F-FLT, 18F-FMISO, and 18F-AlF-NOTA-PRGD2 in a prostate tumor-bearing nude mouse model.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Dideoxynucleosides; Disease Models, Animal; Fluorodeoxyglucose F18; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Male; Mice; Mice, Nude; Misonidazole; Multimodal Imaging; Oligopeptides; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Tissue Distribution; Tomography, X-Ray Computed | 2015 |
Development of novel AAV serotype 6 based vectors with selective tropism for human cancer cells.
Topics: Animals; Capsid Proteins; Cell Line, Tumor; Dependovirus; Disease Models, Animal; Genetic Therapy; Genetic Vectors; HEK293 Cells; Hepatocytes; Humans; Male; Mice; Neoplasms; Oligopeptides; Plasmids; Recombinant Proteins; Transduction, Genetic; Viral Tropism; Xenograft Model Antitumor Assays | 2016 |
Evaluation of GX1 and RGD-GX1 peptides as new radiotracers for angiogenesis evaluation in experimental glioma models.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Glioma; Humans; Mice; Mice, SCID; Neovascularization, Pathologic; Oligopeptides; Radiopharmaceuticals; Technetium; Tomography, Emission-Computed, Single-Photon | 2016 |
Injectable hydrogel promotes early survival of induced pluripotent stem cell-derived oligodendrocytes and attenuates longterm teratoma formation in a spinal cord injury model.
Topics: Animals; Behavior, Animal; Cattle; Cell Differentiation; Cell Lineage; Cell Movement; Cell Survival; Disease Models, Animal; Female; Flow Cytometry; Humans; Hyaluronic Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Induced Pluripotent Stem Cells; Injections; Methylcellulose; Oligodendroglia; Oligopeptides; Platelet-Derived Growth Factor; Rats, Sprague-Dawley; Spinal Cord Injuries; Teratoma | 2016 |
RGD-Targeted Ultrasound Contrast Agent for Longitudinal Assessment of Hep-2 Tumor Angiogenesis In Vivo.
Topics: Acoustics; Animals; Avidin; Binding, Competitive; Biotin; Cell Adhesion; Cell Line; Cell Line, Tumor; Contrast Media; Disease Models, Animal; Endothelial Cells; Female; Humans; Integrin alphaVbeta3; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microbubbles; Microscopy, Fluorescence; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides; Protein Binding; Ultrasonography; Video Recording | 2016 |
Molecular magnetic resonance imaging of activated hepatic stellate cells with ultrasmall superparamagnetic iron oxide targeting integrin αvβ₃ for staging liver fibrosis in rat model.
Topics: Animals; Carbon Tetrachloride; Dextrans; Disease Models, Animal; Hepatic Stellate Cells; Integrin alphaVbeta3; Liver Cirrhosis; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Oligopeptides; Rats | 2016 |
High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive SERRS Molecular Imaging Probe.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Glioblastoma; Integrins; Mice; Molecular Imaging; Nanoparticles; Oligopeptides; Spectrum Analysis, Raman | 2016 |
RGD Peptide Cell-Surface Display Enhances the Targeting and Therapeutic Efficacy of Attenuated Salmonella-mediated Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Breast Neoplasms; Cell Surface Display Techniques; Disease Models, Animal; Drug Carriers; Heterografts; Humans; Integrin alphaVbeta3; Melanoma; Mice; Oligopeptides; Recombinant Fusion Proteins; Salmonella typhimurium; Survival Analysis; Treatment Outcome | 2016 |
Active-target T1-weighted MR Imaging of Tiny Hepatic Tumor via RGD Modified Ultra-small Fe3O4 Nanoprobes.
Topics: Animals; Antineoplastic Agents; Cell Line; Contrast Media; Disease Models, Animal; Ferric Compounds; Humans; Liver Neoplasms; Magnetic Resonance Imaging; Mice; Nanostructures; Oligopeptides; Sensitivity and Specificity | 2016 |
RGD targeting of human ferritin iron oxide nanoparticles enhances in vivo MRI of vascular inflammation and angiogenesis in experimental carotid disease and abdominal aortic aneurysm.
Topics: Animals; Aortic Aneurysm, Abdominal; Carotid Arteries; Carotid Artery Diseases; Disease Models, Animal; Ferric Compounds; Ferritins; Inflammation; Magnetic Resonance Imaging; Male; Mice; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Vascular Diseases | 2017 |
Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma.
Topics: Animals; Antineoplastic Agents; Caspase 3; Cell Line, Tumor; Cell Survival; Disease Models, Animal; DNA Damage; Drug Discovery; Drug Evaluation, Preclinical; Drug Stability; Humans; Integrin alphaVbeta3; Melanoma; Mice; Models, Molecular; Molecular Conformation; Molecular Structure; Oligopeptides; Peptides, Cyclic; Protein Binding; Xenograft Model Antitumor Assays | 2017 |
Targeting integrin α5β1 ameliorates severe airway hyperresponsiveness in experimental asthma.
Topics: Animals; Asthma; Cell Adhesion; Cell Line; Chymases; Disease Models, Animal; Humans; Integrin alpha5beta1; Interleukin-13; Isoproterenol; Mice; Muscle Relaxation; Myocytes, Smooth Muscle; Oligopeptides; Phosphorylation; Rabbits | 2017 |
Preclinical evaluation of radiation and systemic, RGD-targeted, adeno-associated virus phage-TNF gene therapy in a mouse model of spontaneously metastatic melanoma.
Topics: Animals; Cell Line, Tumor; Combined Modality Therapy; Dependovirus; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Genetic Therapy; Genetic Vectors; Melanoma; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Oligopeptides; Radiotherapy; Radiotherapy, Image-Guided; Survival Analysis; Treatment Outcome; Tumor Burden; Tumor Microenvironment; Tumor Necrosis Factor-alpha | 2017 |
VE-cadherin RGD motifs promote metastasis and constitute a potential therapeutic target in melanoma and breast cancers.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Breast Neoplasms; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Models, Animal; Female; Gene Expression; Heterografts; Humans; Integrins; Melanoma; Mice; Models, Biological; Molecular Targeted Therapy; Neoplasm Metastasis; Oligopeptides; Prognosis; Protein Binding; Protein Interaction Domains and Motifs; Protein Interaction Maps; Signal Transduction | 2017 |
Simvastatin augments revascularization and reperfusion in a murine model of hind limb ischemia - Multimodal imaging assessment.
Topics: Animals; Capillaries; Disease Models, Animal; Gene Expression Regulation; Hindlimb; Ischemia; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred BALB C; Multimodal Imaging; Muscles; Neovascularization, Physiologic; Oligopeptides; Regional Blood Flow; Simvastatin; Technetium; Tomography, Emission-Computed, Single-Photon; Vascular Endothelial Growth Factor A | 2017 |
Preparation of arginine-glycine-aspartic acid-modified biopolymeric nanoparticles containing epigalloccatechin-3-gallate for targeting vascular endothelial cells to inhibit corneal neovascularization.
Topics: Angiogenesis Inhibitors; Animals; Burns, Chemical; Catechin; Cell Survival; Corneal Neovascularization; Disease Models, Animal; Eye Burns; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Integrin alphaVbeta3; Mice, Inbred C57BL; Molecular Targeted Therapy; Nanoparticles; Oligopeptides; Ophthalmic Solutions | 2017 |
Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Endothelium; Integrin alphaVbeta3; Kidney Neoplasms; Mice; Nanoparticles; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2008 |
The effect of injected RGD modified alginate on angiogenesis and left ventricular function in a chronic rat infarct model.
Topics: Alginates; Animals; Cell Adhesion; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Glucuronic Acid; Hexuronic Acids; Humans; Myocardial Infarction; Oligopeptides; Rats; Rats, Sprague-Dawley; Ventricular Function, Left; Ventricular Remodeling | 2009 |
Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV.
Topics: Animals; Chemistry, Physical; Choroidal Neovascularization; Disease Models, Animal; Gene Transfer Techniques; Genetic Therapy; Injections, Intravenous; Lasers; Male; Microscopy, Confocal; Nanoparticles; Oligopeptides; Rats; Rats, Inbred BN; Receptors, Vascular Endothelial Growth Factor; Retina; Retinal Pigment Epithelium; Tissue Distribution; Transferrin; Vascular Endothelial Growth Factor A | 2009 |
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Humans; Integrin alphaVbeta3; Lung Neoplasms; Melanoma, Experimental; Mice; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Vascular Endothelial Growth Factor A | 2009 |
Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carbocyanines; Cardiovascular Agents; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Fibrillar Collagens; Fibroblasts; Fibrosis; Losartan; Mice; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; Oligopeptides; Predictive Value of Tests; Spironolactone; Technetium; Tomography, Emission-Computed, Single-Photon; Ventricular Function, Left; Ventricular Remodeling | 2009 |
Cytoprotective effects of a cyclic RGD peptide in steatotic liver cold ischemia and reperfusion injury.
Topics: Animals; Blotting, Western; Cold Temperature; Cytoprotection; Disease Models, Animal; Down-Regulation; Fatty Liver; Immunohistochemistry; In Situ Nick-End Labeling; Interferon-gamma; Matrix Metalloproteinase 9; Neutrophils; Nitric Oxide Synthase Type II; Oligopeptides; Rats; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Survival Rate | 2009 |
Bioartificial matrices for therapeutic vascularization.
Topics: Animals; Disease Models, Animal; Extremities; Hydrogels; Ischemia; Male; Mice; Mice, Inbred Strains; Neovascularization, Physiologic; Oligopeptides; Pharmaceutical Vehicles; Polyethylene Glycols; Rats; Regeneration; Regenerative Medicine; Vascular Endothelial Growth Factor A | 2010 |
The RGD domain of human osteopontin promotes tumor growth and metastasis through activation of survival pathways.
Topics: Animals; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Mice; Mutation; Neoplasm Metastasis; Neoplasm Transplantation; Oligopeptides; Osteopontin; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary | 2010 |
In vivo tumor-targeted fluorescence imaging using near-infrared non-cadmium quantum dots.
Topics: Animals; Disease Models, Animal; Female; Fluorescence; Fluorescent Dyes; Humans; Mice; Mice, Nude; Neoplasms, Experimental; Oligopeptides; Particle Size; Polyethylene Glycols; Quantum Dots | 2010 |
The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat.
Topics: Alginates; Animals; Cell Survival; Disease Models, Animal; Echocardiography; Female; Glucuronic Acid; Hexuronic Acids; Humans; Mesenchymal Stem Cells; Microspheres; Myocardial Infarction; Oligopeptides; Polymerase Chain Reaction; Rats; Rats, Nude; Tissue Engineering | 2010 |
Reproducibility study of [(18)F]FPP(RGD)2 uptake in murine models of human tumor xenografts.
Topics: Animals; Biological Transport; Cell Transformation, Neoplastic; Colonic Neoplasms; Disease Models, Animal; Female; HCT116 Cells; Humans; Injections; Mice; Oligopeptides; Polyethylene Glycols; Positron-Emission Tomography; Reproducibility of Results; Tail; Tumor Burden; Veins | 2011 |
Effect of enamel matrix derivative and parathyroid hormone on bone formation in standardized osseous defects: an experimental study in minipigs.
Topics: Alveolar Ridge Augmentation; Animals; Biocompatible Materials; Bone Regeneration; Bone Substitutes; Cell Adhesion; Dental Enamel Proteins; Disease Models, Animal; Drug Therapy, Combination; Hydrogel, Polyethylene Glycol Dimethacrylate; Oligopeptides; Osteogenesis; Parathyroid Hormone; Peptide Fragments; Statistics, Nonparametric; Swine; Swine, Miniature; Tissue Scaffolds | 2011 |
RGD-conjugated human ferritin nanoparticles for imaging vascular inflammation and angiogenesis in experimental carotid and aortic disease.
Topics: Animals; Aortic Diseases; Carotid Arteries; Carotid Artery Diseases; Cattle; Cells, Cultured; Diagnostic Techniques, Cardiovascular; Disease Models, Animal; Endothelial Cells; Ferritins; Humans; Immunohistochemistry; Inflammation; Macrophages; Male; Mice; Mice, Transgenic; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Protein Binding; Spectrometry, Fluorescence; Spectroscopy, Near-Infrared; Tomography | 2012 |
Interleukin-10 overexpression does not synergize with the neuroprotective action of RGD-containing vectors after postnatal brain excitotoxicity but modulates the main inflammatory cell responses.
Topics: Analysis of Variance; Animals; Animals, Newborn; CD11b Antigen; Cell Death; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Fluoresceins; Gene Expression Regulation; Genetic Vectors; Glial Fibrillary Acidic Protein; Histidine; Interleukin-10; Macrophages; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; Neurotoxicity Syndromes; Neutrophils; Oligopeptides; Organic Chemicals; Peroxidase; Plant Lectins; Rats; Rats, Long-Evans; Transduction, Genetic; Vimentin | 2012 |
Beneficial effects of integrin αvβ3-blocking RGD peptides in early but not late phase of experimental glomerulonephritis.
Topics: Animals; Apoptosis; Cell Proliferation; Cells, Cultured; Creatinine; Crotalid Venoms; Disease Models, Animal; Dose-Response Relationship, Drug; Glomerulonephritis; In Vitro Techniques; Integrin alphaVbeta3; Male; Mesangial Cells; Mice; Mice, Inbred C57BL; Oligopeptides; Time Factors | 2012 |
Functionalized STAT1 siRNA nanoparticles regress rheumatoid arthritis in a mouse model.
Topics: Animals; Arthritis, Rheumatoid; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug Stability; Gene Silencing; Genetic Therapy; Interleukin-10; Lactic Acid; Macrophages; Mice; Nanoparticles; Oligopeptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; STAT1 Transcription Factor | 2011 |
Radiotracers for different angiogenesis receptors in a melanoma model.
Topics: Animals; Disease Models, Animal; Humans; Melanoma; Melanoma, Experimental; Mice; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Polyvinyls; Radioactive Tracers; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Technetium Compounds | 2012 |
Endothelialization and patency of RGD-functionalized vascular grafts in a rabbit carotid artery model.
Topics: Animals; Carotid Arteries; Disease Models, Animal; Endothelium, Vascular; Extracellular Matrix; Fluorescent Antibody Technique; Materials Testing; Microscopy, Electron, Scanning; Muscle, Smooth; Oligopeptides; Platelet Adhesiveness; Polyesters; Prosthesis Implantation; Rabbits; Regeneration; Vascular Grafting; Vascular Patency | 2012 |
Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Ferric Compounds; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Integrin beta3; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Platelet Endothelial Cell Adhesion Molecule-1; Staining and Labeling; Vascular Endothelial Growth Factor A | 2012 |
Tumor angiogenesis phenotyping by nanoparticle-facilitated magnetic resonance and near-infrared fluorescence molecular imaging.
Topics: Animals; Bone Neoplasms; Colorectal Neoplasms; Contrast Media; Disease Models, Animal; Fluorescence; Humans; Immunoenzyme Techniques; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Molecular Imaging; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Sarcoma, Ewing; Spectroscopy, Near-Infrared | 2012 |
Preclinical evaluation of a class of infectivity-enhanced adenoviral vectors in ovarian cancer gene therapy.
Topics: Adenoviridae; Animals; Disease Models, Animal; Female; Gene Targeting; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Mice; Mice, SCID; Neoplasm Transplantation; Oligopeptides; Ovarian Neoplasms; Polylysine; Tumor Cells, Cultured | 2004 |
MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle.
Topics: Animals; Binding, Competitive; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Integrin alphaVbeta3; Lipids; Liposomes; Magnetic Resonance Imaging; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Nanostructures; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Platelet Endothelial Cell Adhesion Molecule-1; Umbilical Veins | 2005 |
Enhancement of adenovirus-mediated gene delivery to rheumatoid arthritis synoviocytes and synovium by fiber modifications: role of arginine-glycine-aspartic acid (RGD)- and non-RGD-binding integrins.
Topics: Adenoviridae; Animals; Arthritis, Rheumatoid; Cytokines; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Humans; Inflammation; Integrins; Mice; Oligopeptides; Organ Culture Techniques; Receptors, Virus; Synovial Membrane; Transduction, Genetic | 2005 |
Identification of OmpU of Vibrio vulnificus as a fibronectin-binding protein and its role in bacterial pathogenesis.
Topics: Adhesins, Bacterial; Animals; Bacterial Adhesion; Disease Models, Animal; Extracellular Matrix; Fibronectins; Humans; Mice; Mutation; Oligopeptides; Vibrio Infections; Vibrio vulnificus | 2006 |
Identifying the safety profile of a novel infectivity-enhanced conditionally replicative adenovirus, Ad5-delta24-RGD, in anticipation of a phase I trial for recurrent ovarian cancer.
Topics: Adenoviridae; Analysis of Variance; Animals; Disease Models, Animal; Female; Gene Transfer Techniques; Genetic Vectors; Injections, Intraperitoneal; Injections, Intravenous; Neoplasm Recurrence, Local; Oligopeptides; Oncolytic Virotherapy; Ovarian Neoplasms; Polymerase Chain Reaction; Probability; Random Allocation; Rats; Rats, Inbred Strains; Reference Values; Sensitivity and Specificity; Sigmodontinae; Survival Analysis | 2007 |
Design, synthesis and cardioprotective effect of a new class of dual-acting agents: phenolic tetrahydro-beta-carboline RGD peptidomimetic conjugates.
Topics: Animals; Carbolines; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Fibrinolytic Agents; Free Radical Scavengers; Molecular Structure; Oligopeptides; PC12 Cells; Phenol; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Thrombosis | 2007 |
Translational activation of 5'-TOP mRNA in pressure overload myocardium.
Topics: Actins; Analysis of Variance; Animals; Blotting, Western; Cats; Cells, Cultured; Disease Models, Animal; Endothelins; Hypertrophy, Right Ventricular; Insulin; Myocytes, Cardiac; Myosin Heavy Chains; Nonmuscle Myosin Type IIB; Oligopeptides; Phosphorylation; Polyribosomes; Protein Biosynthesis; Protein Kinases; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6; Ribosomal Protein S6 Kinases; RNA 5' Terminal Oligopyrimidine Sequence; RNA, Messenger; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; TOR Serine-Threonine Kinases | 2008 |
Cyclic RGD peptides ameliorate ischemic acute renal failure in rats.
Topics: Acute Kidney Injury; Amino Acid Sequence; Animals; Cell Adhesion; Cell Line; Chlorocebus aethiops; Constriction, Pathologic; Disease Models, Animal; Ischemia; Kidney; Kidney Tubules; Male; Molecular Sequence Data; Oligopeptides; Peptides, Cyclic; Protein Conformation; Rats; Rats, Sprague-Dawley | 1994 |
Characterization of murine lung inflammation after infection with parental Bordetella pertussis and mutants deficient in adhesins or toxins.
Topics: Amino Acid Sequence; Animals; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Bacterial Toxins; Bordetella pertussis; Bronchoalveolar Lavage Fluid; Cell Adhesion Molecules; Disease Models, Animal; Hemagglutinins; Inflammation; Lung; Mice; Molecular Sequence Data; Oligopeptides; Pulmonary Alveoli; Virulence; Virulence Factors, Bordetella; Whooping Cough | 1994 |
Accelerated healing of cardiovascular textiles promoted by an RGD peptide.
Topics: Amino Acid Sequence; Animals; Biocompatible Materials; Blood Vessel Prosthesis; Cell Adhesion; Disease Models, Animal; Dogs; Endothelium; Fibronectins; Fibrosis; Heart Valve Prosthesis; Humans; Inflammation; Oligopeptides; Polyethylene Terephthalates; Polytetrafluoroethylene; Prosthesis Design; Receptors, Immunologic; Surface Properties; Surface-Active Agents; Textiles; Thrombosis; Tunica Intima; Wound Healing | 1995 |
A novel synthetic Arg-Gly-Asp-containing peptide cyclo(-RGDf==V-) is the potent inhibitor of angiogenesis.
Topics: Animals; Binding Sites; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic | 2001 |
A new pseudo-peptide of Arg-Gly-Asp (RGD) inhibits intrahepatic metastasis of orthotopically implanted murine hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Adhesion; Cell Death; Cell Division; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Oligopeptides; Tumor Cells, Cultured | 2002 |
Synthesis and antithrombotic activity of carbolinecarboxyl RGD sequence.
Topics: Animals; Carbolines; Cell Adhesion; Disease Models, Animal; Fibrinolytic Agents; Humans; Male; Oligopeptides; Platelet Aggregation; Rabbits; Rats; Rats, Wistar; Structure-Activity Relationship; Thrombosis; Tumor Cells, Cultured | 2002 |
Combined modality radioimmunotherapy. Promise and peril.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cetuximab; Combined Modality Therapy; Disease Models, Animal; Female; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Mortality; Neoplasm Transplantation; Neoplasms, Experimental; Oligopeptides; Paclitaxel; Proto-Oncogene Proteins c-bcl-2; Radioimmunotherapy; Radiotherapy; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2002 |
Kinetics of integrin expression in the mouse model of proliferative retinopathy and success of secondary intervention with cyclic RGD peptides.
Topics: Animals; Diabetic Retinopathy; Disease Models, Animal; Integrins; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Platelet Aggregation Inhibitors; Retinal Vessels | 2002 |
Metalloproteinase inhibitor attenuates neointima formation and constrictive remodeling after angioplasty in rats: augmentative effect of alpha(v)beta(3) receptor blockade.
Topics: Angioplasty, Balloon; Animals; Arteries; Cell Movement; Constriction, Pathologic; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Hydroxamic Acids; Hyperplasia; Male; Matrix Metalloproteinase Inhibitors; Muscle, Smooth, Vascular; Oligopeptides; Phenylalanine; Rats; Receptors, Vitronectin; Thiophenes; Tunica Intima | 2002 |
Antithrombotic properties of L-cysteine, N-(mercaptoacetyl)-D-Tyr-Arg-Gly-Asp-sulfoxide (G4120) in a hamster platelet-rich femoral vein thrombosis model.
Topics: Amino Acid Sequence; Animals; Cricetinae; Disease Models, Animal; Dogs; Femoral Vein; Fibrinolytic Agents; Humans; Male; Molecular Sequence Data; Oligopeptides; Peptides, Cyclic; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rats; Sulfoxides; Thrombosis | 1992 |
RGDV peptide selectively inhibits platelet-dependent thrombus formation in vivo. Studies using a baboon model.
Topics: Amino Acid Sequence; Animals; Blood Platelets; Collagen; Disease Models, Animal; Fibrinolytic Agents; Infusions, Intravenous; Male; Molecular Sequence Data; Oligopeptides; Papio; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis | 1989 |