arginyl-glycyl-aspartic acid has been researched along with Astrocytoma, Grade IV in 63 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.59) | 18.2507 |
2000's | 18 (28.57) | 29.6817 |
2010's | 40 (63.49) | 24.3611 |
2020's | 4 (6.35) | 2.80 |
Authors | Studies |
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Arosio, D; Belvisi, L; Dal Corso, A; Gennari, C; Paolillo, M; Pignataro, L; Sacco, G | 1 |
Liu, H; Tong, H; Xu, K; Xue, W; Zhang, J; Zhang, W; Zhao, Z | 1 |
Dai, S; Hu, F; Liu, Y; Meng, T; Qiu, G; Tan, Y; Wen, L; Yu, F; Yuan, H; Zhu, Y | 1 |
Choy, CJ; Coombes, JD; Kenny, SJ; Kumar, S; Lee, S; Shukla, P; Springer, K; Wolf, KJ; Xu, K | 1 |
Bradley, M; Chankeshwara, SV; Clavadetscher, J; Indrigo, E; Lilienkampf, A | 1 |
Deng, G; Liu, Q; Wang, J; Wang, Q; Wang, X; Yang, H; Yang, S; Zhao, H; Zhou, P; Zhou, Z | 1 |
Brancaccio, D; Cavallini, C; Cerofolini, L; Costa, B; Da Settimo, F; Daniele, S; Di Leva, FS; Di Maro, S; Fragai, M; Giuntini, S; Kessler, H; La Pietra, V; Luchinat, C; Marinelli, L; Martini, C; Merlino, F; Novellino, E; Piccarducci, R; Reichart, F; Taliani, S; Tomassi, S | 1 |
Merabtene, F; Nataf, V; Prignon, A; Provost, C; Rozenblum-Beddok, L; Talbot, JN | 1 |
Bierman, RD; Ehsanipour, A; Liang, J; Liu, S; Nathanson, DA; Seidlits, SK; Sohrabi, A; Wang, S; Xiao, W; Yu, Q; Zhang, R | 1 |
An, X; Ge, H; Gu, T; Guo, L; Jiang, Q; Meng, X; Ning, X; Shan, X; Zhang, L | 1 |
Che, Y; Chen, H; Ito, M; Paholak, H; Qian, W; Sansanaphongpricha, K; Sun, D | 1 |
Bouchaud, V; Franconi, JM; Mellet, P; Miraux, S; Moncelet, D; Ribot, E; Voisin, P | 1 |
Brandt-Larsen, M; El-Ali, HH; Kjaer, A; Madsen, J; Myschetzky, R; Oxboel, J; Schjoeth-Eskesen, C | 1 |
Han, Y; Li, H; Tian, Y; Wang, Q; Wu, H; Zhou, W | 1 |
Cao, S; Gao, H; Jiang, X; Xiong, Y; Yang, Z; Zhang, S | 1 |
Kim, Y; Kumar, S | 1 |
Chen, X; Guo, J; Huang, X; Jacobson, O; Kiesewetter, DO; Liu, D; Niu, G; Sun, S; Sun, X; Szajek, LP; Wang, Y; Yan, X; Zhu, W | 1 |
Cheng, L; Cheng, R; Liu, Z; Meng, F; Wang, C; Zhong, Y; Zhong, Z | 1 |
Ahn, H; An, GI; Bhatt, N; Ha, YS; Kim, JY; Lee, H; Lee, W; Lee, YJ; Pandya, DN; Soni, N; Yoo, J | 1 |
Bouziotis, P; Fragogeorgi, EA; Kagadis, GC; Karnabatidis, D; Loudos, G; Palamaris, L; Paravatou-Petsotas, M; Psimadas, D; Tsiapa, I; Varvarigou, AD; Xanthopoulos, S | 1 |
Chen, Y; Chong, HS; Kang, CS; Kweon, J; Lee, H; Lewis, MR; Liu, D; Sun, X | 1 |
Fan, D; Jia, B; Liu, X; Liu, Z; Shi, J; Sun, Y; Wang, F; Zhang, X; Zhao, H; Zhong, L; Zhu, Z | 1 |
Chen, Q; Feng, L; Li, Y; Liu, Z; Wang, C; Wang, X | 1 |
Gao, H; He, Q; Liu, Y; Shi, K; Zhang, Q; Zhou, J; Zong, T | 1 |
Akay, M; Akay, YM; Avci, NG; Dragomir, A; Fan, Y; Fueyo-Margareto, J; Gomez-Manzano, C | 1 |
Li, Z; Yao, T; Zhang, C; Zhang, L; Zhang, Q; Zheng, Y; Zhou, D | 1 |
Chen, Z; Diao, Y; Hou, J; Li, W; Wu, Y; Yang, Z; Zhang, L | 1 |
Harmsen, S; Holland, EC; Huang, R; Karabeber, H; Kircher, MF; Pitter, KL; Samii, JM | 1 |
Alves, CS; Kong, L; Shi, X; Wu, Y | 1 |
Boucher, M; Lalatonne, Y; Mériaux, S; Motte, L; Richard, S | 1 |
Dou, NN; Gao, G; Liu, MX; Visocchi, M; Zhong, J | 1 |
Boturyn, D; Degardin, M; Dumy, P; Fujibayashi, Y; Furukawa, T; Higashi, T; Jin, ZH; Ohya, T; Saga, T; Sugyo, A; Tsuji, AB; Zhang, MR | 1 |
Mikkelsen, T; Nabors, LB; Reardon, DA; Stupp, R | 1 |
Chen, K; Chen, X; Hsu, AR; Lee, HY; Li, Z; Sun, S; Xie, J; Xu, C | 1 |
Cheng, Z; Cochran, JR; Gambhir, SS; Kimura, RH | 1 |
Czernin, JG; Dumont, RA; Haubner, R; Hildebrandt, I; Mischel, PS; Reischl, G; Su, H; Weber, WA | 1 |
Chen, X; Li, ZB | 1 |
De Luca, S; Del Gatto, A; Del Vecchio, S; Grieco, P; Iommelli, F; Novellino, E; Panico, M; Papaccioli, A; Pedone, C; Salvatore, M; Saviano, M; Sommella, J; Speranza, A; Zaccaro, L; Zannetti, A | 1 |
Behera, D; Biswal, S; Chen, K; Chen, X; Michalski, MH; Wang, A; Xie, J; Xu, H | 1 |
Addadi, Y; Eisenhut, M; Huppert, J; Jayapaul, J; Kiessling, F; Mueller, MM; Neeman, M; Semmler, W; Woenne, EC; Zentgraf, H; Zhang, C; Zwick, S | 1 |
Andreeff, M; Bogler, O; Fueyo, J; Gumin, J; Lang, FF; Marini, FC; Shinojima, N; Vecil, GG; Yong, RL | 1 |
Gu, B; Li, C; Liu, M; Lu, W; Lu, WY; Lv, Y; Mao, Y; Pazgier, M; Wei, G; Yuan, W; Zhan, C | 1 |
Nabors, LB; Neyns, B; Reardon, DA; Stupp, R; Tonn, JC; Weller, M | 1 |
Cheng, Z; Jiang, H; Liu, H; Liu, S; Xu, Y; Zhang, H | 1 |
Cho, G; Cho, JH; Choi, N; Hong, KS; Kim, SM; Lee, C; Ryu, EK | 1 |
Alves, F; Dullin, C; Kessler, H; Mathejczyk, JE; Napp, J; Pauli, J; Resch-Genger, U; Tietze, LF | 1 |
Li, C; Lu, W; Shen, J; Wei, X; Xie, C | 1 |
Arosio, D; Bartolomeo, MP; Belvisi, L; Bianchi, A; Brioschi, C; Buonsanti, F; Cabella, C; Casagrande, C; Civera, M; De Matteo, M; Fugazza, L; Lattuada, L; Maisano, F; Manzoni, L; Miragoli, L; Neira, C; Pilkington-Miksa, M; Scolastico, C | 1 |
Chen, X; Guo, N; Huang, X; Lee, S; Lu, G; Mohamedali, KA; Niu, G; Rosenblum, MG; Swierczewska, M; Wang, AY; Xu, H; Zhang, F; Zhu, L | 1 |
Chen, J; Rotstein, BH; Roxin, Á; Scully, CC; Yudin, AK; Zheng, G | 1 |
Blasberg, RG; Huang, R; Kircher, MF; Kovar, JL; Mayer-Kuckuk, P; Mellinghoff, IK; Olive, DM; Vider, J | 1 |
Ciusani, E; Colombo, L; Curti, D; Paolillo, M; Russo, MA; Sanchez-Hernandez, Y; Schinelli, S; Serra, M | 1 |
Hong, S; Im, K; Kang, JH; Kang, M; Lee, J; Lee, TS; Lim, SM; Park, S; Ryu, J; Song, R | 1 |
Alemany, R; Curiel, DT; Dirven, CM; Fueyo, J; Geoerger, B; Gerritsen, WR; Grill, J; Lamfers, ML; Pinedo, HM; Van Beusechem, VW; Van Den Berg, J; Vandertop, WP; Vassal, G | 1 |
Bading, JR; Chen, X; Conti, PS; Park, R; Shahinian, AH | 1 |
Bading, JR; Bozorgzadeh, MH; Chen, X; Conti, PS; Khankaldyyan, V; Laug, WE; Moats, R; Park, R; Shahinian, AH; Tohme, M | 1 |
Bading, JR; Chen, X; Conti, PS; Hou, Y; Park, R; Tohme, M | 1 |
Bading, JR; Chen, X; Conti, PS; Gonzales-Gomez, I; Hou, Y; Khankaldyyan, V; Laug, WE; Park, R; Tohme, M | 1 |
Cai, W; Cao, Q; Chen, K; Chen, X; Gambhir, SS; Gheysens, O; Shin, DW; Wang, SX | 1 |
Cai, W; Chen, X; Chin, FT; He, L; Li, F; Li, ZB; Wu, Z | 1 |
Chen, K; Chen, X; Li, ZB | 1 |
Gladson, CL; Grammer, JR; Murphy-Ullrich, JE; Pearce, SF; Pijuan-Thompson, V; Silverstein, RL; Stewart, J; Tuszynski, GP | 1 |
Adamson, E; Liu, C; Mercola, D; Yao, J | 1 |
1 review(s) available for arginyl-glycyl-aspartic acid and Astrocytoma, Grade IV
Article | Year |
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Cilengitide: an integrin-targeting arginine-glycine-aspartic acid peptide with promising activity for glioblastoma multiforme.
Topics: Animals; Antineoplastic Agents; Central Nervous System Neoplasms; Clinical Trials as Topic; Drug Evaluation, Preclinical; Glioblastoma; Humans; Integrins; Models, Molecular; Oligopeptides; Protein Binding; Snake Venoms; Treatment Outcome | 2008 |
62 other study(ies) available for arginyl-glycyl-aspartic acid and Astrocytoma, Grade IV
Article | Year |
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A dimeric bicyclic RGD ligand displays enhanced integrin binding affinity and strong biological effects on U-373 MG glioblastoma cells.
Topics: Binding Sites; Cell Adhesion; Cell Line, Tumor; Dimerization; Extracellular Matrix Proteins; Focal Adhesion Kinase 1; Glioblastoma; Humans; Integrins; Ligands; Oligopeptides; Peptides, Cyclic; Phosphorylation | 2019 |
Albumin-stabilized manganese-based nanocomposites with sensitive tumor microenvironment responsivity and their application for efficient SiRNA delivery in brain tumors.
Topics: Animals; Brain Neoplasms; Cattle; Cell Survival; Drug Delivery Systems; Female; Glioblastoma; Humans; Manganese; Mice; Mice, Inbred BALB C; Mice, Nude; Nanocomposites; Neoplasms, Experimental; Oligopeptides; Optical Imaging; Particle Size; RNA, Small Interfering; Serum Albumin, Bovine; Surface Properties; Tumor Cells, Cultured; Tumor Microenvironment | 2020 |
Enhancing Drug Delivery for Overcoming Angiogenesis and Improving the Phototherapy Efficacy of Glioblastoma by ICG-Loaded Glycolipid-Like Micelles.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Endothelial Cells; Glioblastoma; Glycolipids; Humans; Indocyanine Green; Mice, Nude; Micelles; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Photosensitizing Agents; Phototherapy; Tissue Distribution; Xenograft Model Antitumor Assays | 2020 |
A mode of cell adhesion and migration facilitated by CD44-dependent microtentacles.
Topics: Actins; Animals; Brain; Cell Adhesion; Cell Line, Tumor; Cell Movement; Extracellular Matrix; Female; Gene Knockout Techniques; Glioblastoma; Humans; Hyaluronan Receptors; Hyaluronic Acid; Mice; Microtubule-Associated Proteins; Microtubules; Myosins; Neoplasm Proteins; Oligopeptides; Organ Culture Techniques; ras GTPase-Activating Proteins | 2020 |
In-Cell Dual Drug Synthesis by Cancer-Targeting Palladium Catalysts.
Topics: Antineoplastic Agents; Brain Neoplasms; Catalysis; Cell Line, Tumor; Drug Delivery Systems; Fluorescent Dyes; Glioblastoma; Humans; Metal Nanoparticles; Microscopy, Fluorescence; Oligopeptides; Palladium; Prodrugs | 2017 |
Photoacoustic-Enabled Self-Guidance in Magnetic-Hyperthermia Fe@Fe
Topics: Animals; Cell Line, Tumor; Glioblastoma; Humans; Hyperthermia, Induced; Magnetic Field Therapy; Magnetite Nanoparticles; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Photoacoustic Techniques; Theranostic Nanomedicine; Xenograft Model Antitumor Assays | 2018 |
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.
Topics: Animals; Cell Line, Tumor; Glioblastoma; Integrin alpha5beta1; Integrin alphaVbeta3; Mice; Models, Molecular; Molecular Targeted Therapy; Oligopeptides; Peptidomimetics; Protein Conformation; Proto-Oncogene Proteins c-mdm2 | 2018 |
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Topics: Animals; Bevacizumab; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Fluorodeoxyglucose F18; Gallium Radioisotopes; Glioblastoma; Humans; Mice; Oligopeptides; Positron-Emission Tomography; Temozolomide; Tissue Distribution; Treatment Outcome; Tumor Burden | 2019 |
Bioengineered scaffolds for 3D culture demonstrate extracellular matrix-mediated mechanisms of chemotherapy resistance in glioblastoma.
Topics: Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Extracellular Matrix; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hyaluronan Receptors; Hyaluronic Acid; Integrin alphaV; Models, Biological; Oligopeptides; Temozolomide; Tissue Scaffolds; Tumor Microenvironment | 2020 |
Novel Integrin αvβ3-Specific Ligand for the Sensitive Diagnosis of Glioblastoma.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Gene Knockout Techniques; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Ligands; Male; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Optical Imaging; Protein Binding; Snake Venoms; Transfection; Xenograft Model Antitumor Assays | 2019 |
'Living' PEGylation on gold nanoparticles to optimize cancer cell uptake by controlling targeting ligand and charge densities.
Topics: Biological Transport; Cell Line, Tumor; Drug Delivery Systems; Glioblastoma; Gold; Humans; Macrophages; Nanoparticles; Oligopeptides; Polyethylene Glycols | 2013 |
Cellular density effect on RGD ligand internalization in glioblastoma for MRI application.
Topics: Cell Count; Cell Line, Tumor; Endocytosis; Flow Cytometry; Glioblastoma; Humans; Ligands; Magnetic Resonance Imaging; Neoplasm Grading; Neoplasm Invasiveness; Oligopeptides; Sensitivity and Specificity; Signal-To-Noise Ratio | 2013 |
Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E[c(RGDyK)]2 and (64)Cu-NODAGA-E[c(RGDyK)]2; in vivo imaging studies in human xenograft tumors.
Topics: Acetates; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Copper Radioisotopes; Female; Gallium Radioisotopes; Glioblastoma; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiochemistry; Radiometry; Tissue Distribution; Tomography, X-Ray Computed | 2014 |
[Tumor targeting efficacy of a novel PET radiotracer (1)8F-AlF-NOTA-PRGD2 in mice].
Topics: Animals; Cell Line, Tumor; Fluorine Radioisotopes; Glioblastoma; Humans; Mice; Mice, Nude; Oligopeptides; Positron-Emission Tomography; Radioactive Tracers | 2014 |
RGD and interleukin-13 peptide functionalized nanoparticles for enhanced glioblastoma cells and neovasculature dual targeting delivery and elevated tumor penetration.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Cell Membrane Permeability; Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Endocytosis; Flow Cytometry; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Mice; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Pathologic; Oligopeptides | 2014 |
CD44-mediated adhesion to hyaluronic acid contributes to mechanosensing and invasive motility.
Topics: Brain Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Shape; Fibronectins; Glioblastoma; Humans; Hyaluronan Receptors; Hyaluronic Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Integrins; Mechanotransduction, Cellular; Models, Biological; Neoplasm Invasiveness; Oligopeptides | 2014 |
Chelator-free (64)Cu-integrated gold nanomaterials for positron emission tomography imaging guided photothermal cancer therapy.
Topics: Animals; Cell Line, Tumor; Copper; Copper Radioisotopes; Glioblastoma; Gold; Humans; Mice; Nanostructures; Nanotubes; Oligopeptides; Oxidation-Reduction; Phototherapy; Polyethylene Glycols; Positron-Emission Tomography; Tissue Distribution | 2014 |
cRGD-directed, NIR-responsive and robust AuNR/PEG-PCL hybrid nanoparticles for targeted chemotherapy of glioblastoma in vivo.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Doxorubicin; Drug Carriers; Glioblastoma; Gold; Humans; Mice, Nude; Nanoparticles; Nanotubes; Oligopeptides; Polyesters; Polyethylene Glycols; Tissue Distribution; Xenograft Model Antitumor Assays | 2014 |
Propylene cross-bridged macrocyclic bifunctional chelator: a new design for facile bioconjugation and robust (64)Cu complex stability.
Topics: Alkenes; Animals; Chelating Agents; Coordination Complexes; Copper; Copper Radioisotopes; Drug Design; Glioblastoma; Heterocyclic Compounds; Humans; Macrocyclic Compounds; Mice; Mice, Nude; Models, Chemical; Molecular Structure; Oligopeptides; Positron-Emission Tomography; Rats; Tissue Distribution; Transplantation, Heterologous | 2014 |
Evaluation of ανβ3-mediated tumor expression with a 99mTc-labeled ornithine-modified RGD derivative during glioblastoma growth in vivo.
Topics: Animals; Cell Line, Tumor; Glioblastoma; Humans; Integrin alphaVbeta3; Isotope Labeling; Mice; Mice, SCID; Neovascularization, Pathologic; Oligopeptides; Ornithine; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Tissue Distribution | 2014 |
Synthesis and evaluation of a new bifunctional NETA chelate for molecular targeted radiotherapy using(90)Y or(177)Lu.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Chemistry Techniques, Synthetic; Drug Stability; Glioblastoma; Heterocyclic Compounds; Humans; Isotope Labeling; Kinetics; Lutetium; Mice; Molecular Targeted Therapy; Oligopeptides; Tissue Distribution; Yttrium Radioisotopes | 2015 |
(68)Ga-labeled 3PRGD2 for dual PET and Cerenkov luminescence imaging of orthotopic human glioblastoma.
Topics: Animals; Cell Line, Tumor; Female; Fluorodeoxyglucose F18; Gallium Radioisotopes; Glioblastoma; Humans; Luminescence; Luminescent Measurements; Mice; Mice, Inbred BALB C; Oligopeptides; Optical Imaging; Organometallic Compounds; Peptides, Cyclic; Positron-Emission Tomography; Tissue Distribution | 2015 |
Drug-Induced Self-Assembly of Modified Albumins as Nano-theranostics for Tumor-Targeted Combination Therapy.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chlorophyllides; Combined Modality Therapy; Female; Glioblastoma; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Models, Molecular; Molecular Targeted Therapy; Oligopeptides; Paclitaxel; Porphyrins; Protein Aggregates; Protein Conformation; Serum Albumin; Theranostic Nanomedicine | 2015 |
Arginine-Glycine-Aspartic Acid-Modified Lipid-Polymer Hybrid Nanoparticles for Docetaxel Delivery in Glioblastoma Multiforme.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Diffusion; Docetaxel; Glioblastoma; Lipids; Nanocapsules; Nanocomposites; Oligopeptides; Polymers; Rats; Rats, Sprague-Dawley; Survival Rate; Taxoids; Treatment Outcome | 2015 |
Delta-24-RGD Induces Cytotoxicity of Glioblastoma Spheroids in Three Dimensional PEG Microwells.
Topics: Adenoviridae; Cell Culture Techniques; Cell Line, Tumor; Gene Transfer Techniques; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Hydrogels; Models, Biological; Oligopeptides; Polyethylene Glycols; Spheroids, Cellular; Tumor Cells, Cultured; Tumor Microenvironment | 2015 |
Development of next generation adeno-associated viral vectors capable of selective tropism and efficient gene delivery.
Topics: Amino Acid Sequence; Animals; Capsid Proteins; Cell Line; Cell Line, Tumor; Dependovirus; Drug Carriers; Gene Transfer Techniques; Genetic Code; Genetic Therapy; Genetic Vectors; Glioblastoma; Humans; Mice, Inbred BALB C; Mice, Nude; Models, Molecular; Oligopeptides; Protein Engineering; Transduction, Genetic | 2016 |
RGD peptide conjugation results in enhanced antitumor activity of PD0325901 against glioblastoma by both tumor-targeting delivery and combination therapy.
Topics: Animals; Antineoplastic Agents; Benzamides; Cell Proliferation; Central Nervous System Neoplasms; Diphenylamine; Drug Delivery Systems; Drug Liberation; Drug Synergism; Female; Glioblastoma; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Inbred BALB C; Oligopeptides; Xenograft Model Antitumor Assays | 2016 |
High Precision Imaging of Microscopic Spread of Glioblastoma with a Targeted Ultrasensitive SERRS Molecular Imaging Probe.
Topics: Animals; Brain Neoplasms; Disease Models, Animal; Glioblastoma; Integrins; Mice; Molecular Imaging; Nanoparticles; Oligopeptides; Spectrum Analysis, Raman | 2016 |
Efficient delivery of therapeutic siRNA into glioblastoma cells using multifunctional dendrimer-entrapped gold nanoparticles.
Topics: Animals; Cell Line, Tumor; Dendrimers; Drug Delivery Systems; Drug Liberation; Gene Silencing; Glioblastoma; Gold; Humans; Metal Nanoparticles; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Particle Size; Polyethylene Glycols; RNA, Small Interfering; Transfection | 2016 |
Iron oxide nanoparticle surface decorated with cRGD peptides for magnetic resonance imaging of brain tumors.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Contrast Media; Ferric Compounds; Glioblastoma; Heterografts; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Mice, Nude; Nanomedicine; Oligopeptides; Predictive Value of Tests; Surface Properties | 2017 |
One-Pot Aqueous Synthesization of Near-Infrared Quantum Dots for Bioimaging and Photodynamic Therapy of Gliomas.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Brain Neoplasms; Cadmium Compounds; Cell Line, Tumor; Cell Survival; Glioblastoma; Glioma; Humans; In Vitro Techniques; Low-Level Light Therapy; Mice; Microscopy, Confocal; Oligopeptides; Photochemotherapy; Quantum Dots; Tellurium | 2017 |
67Cu-Radiolabeling of a multimeric RGD peptide for αVβ3 integrin-targeted radionuclide therapy: stability, therapeutic efficacy, and safety studies in mice.
Topics: Animals; Cell Line, Tumor; Copper Radioisotopes; Drug Stability; Female; Glioblastoma; Humans; Integrin alphaVbeta3; Isotope Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Oligopeptides; Organometallic Compounds; Radiopharmaceuticals; Radiotherapy Dosage; Treatment Outcome; Xenograft Model Antitumor Assays | 2017 |
PET/MRI dual-modality tumor imaging using arginine-glycine-aspartic (RGD)-conjugated radiolabeled iron oxide nanoparticles.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Female; Ferric Compounds; Glioblastoma; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanoparticles; Neoplasm Transplantation; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Transplantation, Heterologous | 2008 |
Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain Neoplasms; Carbocyanines; Cell Line, Tumor; Copper Radioisotopes; Glioblastoma; Heterocyclic Compounds, 1-Ring; Humans; Integrins; Mice; Mice, Nude; Molecular Sequence Data; Oligopeptides; Peptides; Positron-Emission Tomography; Spectroscopy, Near-Infrared; Substrate Specificity; Transplantation, Heterologous | 2009 |
Noninvasive imaging of alphaVbeta3 function as a predictor of the antimigratory and antiproliferative effects of dasatinib.
Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Copper Radioisotopes; Dasatinib; Focal Adhesions; Glioblastoma; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Male; Mice; Mice, SCID; Oligopeptides; Organometallic Compounds; Positron-Emission Tomography; Protein Kinase Inhibitors; Pyrimidines; src-Family Kinases; Thiazoles | 2009 |
MicroPET, MicroSPECT, and NIR fluorescence imaging of biomolecules in vivo.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Fluorescence; Fluorine Radioisotopes; Glioblastoma; Humans; Infrared Rays; Integrin alphaVbeta3; Mice; Mice, Nude; Molecular Probe Techniques; Molecular Probes; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Technetium; Tomography, Emission-Computed, Single-Photon | 2009 |
Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5).
Topics: Amino Acid Sequence; Animals; Glioblastoma; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; K562 Cells; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Oligopeptides; Peptides; Positron-Emission Tomography; Protein Binding; Receptors, Vitronectin; Recombinant Fusion Proteins; Substrate Specificity; Transplantation, Heterologous; Tumor Cells, Cultured | 2009 |
Triblock copolymer coated iron oxide nanoparticle conjugate for tumor integrin targeting.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Ferric Compounds; Fluorescent Dyes; Glioblastoma; Humans; Integrins; Materials Testing; Mice; Molecular Structure; Nanoparticles; Neoplasms; Oligopeptides; Polymers; Surface Properties; Tissue Distribution; Transplantation, Heterologous | 2009 |
RGD-labeled USPIO inhibits adhesion and endocytotic activity of alpha v beta3-integrin-expressing glioma cells and only accumulates in the vascular tumor compartment.
Topics: Animals; Cell Adhesion; Cell Line, Tumor; Cell Survival; Cells, Cultured; Contrast Media; Dextrans; Endocytosis; Endothelium, Vascular; Female; Ferrosoferric Oxide; Fluorescent Antibody Technique; Glioblastoma; Glioma; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Nude; Neoplasm Transplantation; Oligopeptides; Ovarian Neoplasms; Umbilical Veins | 2009 |
Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus Delta24-RGD to human gliomas.
Topics: Adenoviridae; Adenovirus E1A Proteins; Animals; Bone Marrow Cells; Brain Neoplasms; Glioblastoma; Humans; Injections, Intra-Arterial; Male; Mesenchymal Stem Cells; Mice; Mice, Nude; Oligopeptides; Oncolytic Virotherapy; Transduction, Genetic; Virus Replication; Xenograft Model Antitumor Assays | 2009 |
D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms.
Topics: Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Liposomes; Mice; Mice, Nude; Oligopeptides; Peptides; Protein Binding; Proto-Oncogene Proteins c-mdm2; Transplantation, Heterologous; Tumor Suppressor Protein p53 | 2010 |
Cilengitide: an RGD pentapeptide ανβ3 and ανβ5 integrin inhibitor in development for glioblastoma and other malignancies.
Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Drug Evaluation, Preclinical; Drug Industry; Glioblastoma; Humans; Integrins; Oligopeptides; Snake Venoms; Treatment Outcome | 2011 |
One-step radiosynthesis of ¹⁸F-AlF-NOTA-RGD₂ for tumor angiogenesis PET imaging.
Topics: Animals; Cell Line, Tumor; Drug Stability; Female; Glioblastoma; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Integrins; Mice; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiochemistry | 2011 |
The use of the fusion protein RGD-HSA-TIMP2 as a tumor targeting imaging probe for SPECT and PET.
Topics: Animals; Cell Line, Tumor; Gadolinium; Glioblastoma; Humans; Iodine Radioisotopes; Male; Materials Testing; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Oligopeptides; Positron-Emission Tomography; Recombinant Fusion Proteins; Serum Albumin; Tissue Inhibitor of Metalloproteinase-2; Tomography, Emission-Computed, Single-Photon | 2011 |
Spectroscopically well-characterized RGD optical probe as a prerequisite for lifetime-gated tumor imaging.
Topics: Animals; Carbocyanines; Cell Line, Tumor; Fluorescent Dyes; Glioblastoma; Humans; Integrin alphaVbeta3; Male; Mice; Mice, Nude; Molecular Imaging; Molecular Probes; Neoplasm Transplantation; Oligopeptides; Protein Binding; Spectroscopy, Near-Infrared; Transplantation, Heterologous | 2011 |
Targeted delivery of a novel palmitylated D-peptide for antiglioblastoma molecular therapy.
Topics: Acylation; Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Compounding; Glioblastoma; Humans; Lipopeptides; Liposomes; Male; Mice; Mice, Nude; Molecular Targeted Therapy; Oligopeptides; Palmitic Acid; Peptides, Cyclic; Proto-Oncogene Proteins c-mdm2; Random Allocation; Stereoisomerism; Surface Properties; Tumor Suppressor Protein p53 | 2012 |
Synthesis of Gd and (68)Ga complexes in conjugation with a conformationally optimized RGD sequence as potential MRI and PET tumor-imaging probes.
Topics: Animals; Cell Line, Tumor; Coordination Complexes; Gadolinium; Gallium Radioisotopes; Glioblastoma; Humans; Magnetic Resonance Imaging; Mice; Mice, Nude; Models, Molecular; Oligopeptides; Positron-Emission Tomography; Protein Binding; Radiopharmaceuticals; Transplantation, Heterologous | 2012 |
Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Ferric Compounds; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Integrin beta3; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Platelet Endothelial Cell Adhesion Molecule-1; Staining and Labeling; Vascular Endothelial Growth Factor A | 2012 |
Conformational modulation of in vitro activity of cyclic RGD peptides via aziridine aldehyde-driven macrocyclization chemistry.
Topics: Aldehydes; Aziridines; Cyanides; Cyclization; Glioblastoma; Humans; Macrocyclic Compounds; Models, Molecular; Molecular Conformation; Oligopeptides; Peptides, Cyclic; Tumor Cells, Cultured | 2012 |
Integrin αvβ3-targeted IRDye 800CW near-infrared imaging of glioblastoma.
Topics: Animals; Benzenesulfonates; Cell Line, Tumor; Glioblastoma; Humans; Indoles; Integrin alphaVbeta3; Mice; Mice, Transgenic; Molecular Imaging; Neoplasms, Experimental; Oligopeptides; Radiography; Spectroscopy, Near-Infrared; Tissue Distribution | 2012 |
A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells.
Topics: Actin Cytoskeleton; Anoikis; Blotting, Western; Brain Neoplasms; Cell Adhesion; Cell Movement; Cell Proliferation; Enzyme-Linked Immunosorbent Assay; Focal Adhesion Protein-Tyrosine Kinases; Glioblastoma; Humans; Immunoenzyme Techniques; Integrin alphaVbeta3; Oligopeptides; Phosphorylation; Real-Time Polymerase Chain Reaction; Receptors, Vitronectin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 2013 |
RGD peptide-conjugated multimodal NaGdF4:Yb3+/Er3+ nanophosphors for upconversion luminescence, MR, and PET imaging of tumor angiogenesis.
Topics: Animals; Cell Line, Tumor; Dimerization; Erbium; Feasibility Studies; Fluorides; Gadolinium; Glioblastoma; Humans; Integrin alphaVbeta3; Iodine Radioisotopes; Luminescent Agents; Luminescent Measurements; Magnetic Resonance Imaging; Mice; Molecular Imaging; Nanostructures; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Positron-Emission Tomography; Ytterbium | 2013 |
Potential of the conditionally replicative adenovirus Ad5-Delta24RGD in the treatment of malignant gliomas and its enhanced effect with radiotherapy.
Topics: Adenoviridae; Adult; Aged; Animals; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Female; Glioblastoma; Humans; Integrin alphaVbeta3; Integrins; Male; Mice; Mice, Nude; Middle Aged; Oligopeptides; Receptors, Virus; Receptors, Vitronectin; Spheroids, Cellular; Tumor Cells, Cultured; Virus Replication; Xenograft Model Antitumor Assays | 2002 |
Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by PEGylation.
Topics: Animals; Glioblastoma; Iodine Radioisotopes; Male; Metabolic Clearance Rate; Mice; Mice, Nude; Oligopeptides; Organ Specificity; Polyethylene Glycols; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution | 2004 |
18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Feasibility Studies; Female; Fluorine Radioisotopes; Glioblastoma; Humans; Integrin alphaVbeta3; Metabolic Clearance Rate; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Organ Specificity; Pilot Projects; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution | 2004 |
Micro-PET imaging of alphavbeta3-integrin expression with 18F-labeled dimeric RGD peptide.
Topics: Animals; Brain; Capillaries; Cells, Cultured; Dimerization; Endothelium, Vascular; Female; Fluorine Radioisotopes; Glioblastoma; Glutamic Acid; Humans; Integrin alphaVbeta3; Isotope Labeling; Kidney; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography; Radiopharmaceuticals; Reference Standards; Time Factors; Transplantation, Heterologous | 2004 |
Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression.
Topics: Animals; Brain Neoplasms; Copper Radioisotopes; Female; Glioblastoma; Integrin alphaVbeta3; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Oligopeptides; Organ Specificity; Peptides; Polyethylene Glycols; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution | 2004 |
Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects.
Topics: Animals; Cell Line, Tumor; Coated Materials, Biocompatible; Glioblastoma; Humans; Mice; Mice, Nude; Microscopy, Fluorescence; Neovascularization, Pathologic; Oligopeptides; Particle Size; Quantum Dots; Spectrophotometry, Infrared; Whole Body Imaging | 2006 |
18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2): synthesis and microPET imaging of alphavbeta3 integrin expression.
Topics: Animals; Dimerization; Female; Fluorine Radioisotopes; Gene Expression Profiling; Glioblastoma; Integrin alphaVbeta3; Metabolic Clearance Rate; Mice; Mice, Nude; Oligopeptides; Organ Specificity; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution | 2007 |
(68)Ga-labeled multimeric RGD peptides for microPET imaging of integrin alpha(v)beta (3) expression.
Topics: Animals; Cell Line, Tumor; Dimerization; Female; Gallium Radioisotopes; Glioblastoma; Humans; Integrin alphaVbeta3; Isotope Labeling; Metabolic Clearance Rate; Mice; Mice, Nude; Oligopeptides; Organ Specificity; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution | 2008 |
Retinoic acid alters the mechanism of attachment of malignant astrocytoma and neuroblastoma cells to thrombospondin-1.
Topics: Astrocytes; Astrocytoma; Brain; CD36 Antigens; Cell Adhesion; Cell Differentiation; Chondroitin ABC Lyase; Chondroitin Sulfates; Cytoskeleton; Endothelium; Ganglioneuroblastoma; Ganglioneuroma; Glioblastoma; Heparin; Humans; Integrin alpha3beta1; Integrins; Neuroblastoma; Neurons; Oligopeptides; Peptide Fragments; Polysaccharide-Lyases; Receptors, Fibronectin; Recombinant Proteins; Thrombospondin 1; Tretinoin; Tumor Cells, Cultured | 1999 |
The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251.
Topics: Antibodies; Binding Sites; Cell Adhesion; Cell Movement; DNA-Binding Proteins; Early Growth Response Protein 1; Extracellular Matrix; Fibronectins; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glioblastoma; Humans; Immediate-Early Proteins; Mutation; Oligopeptides; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Transcription Factors; Transcriptional Activation; Transforming Growth Factor beta; Tumor Cells, Cultured | 2000 |