arginyl-glycyl-aspartic acid has been researched along with Angiogenesis, Pathologic in 167 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (3.59) | 18.2507 |
| 2000's | 71 (42.51) | 29.6817 |
| 2010's | 84 (50.30) | 24.3611 |
| 2020's | 6 (3.59) | 2.80 |
| Authors | Studies |
|---|---|
| Balasse, L; Blot-Chabaud, M; Brige, P; Dignat-George, F; Fernandez, S; Garrigue, P; Guillet, B; Hache, G; Hubert, F; Moyon, A; Nail, V; Rochais, F | 1 |
| Kesharwani, P; Md, S; Sheikh, A | 1 |
| Bañobre, M; Belderbos, S; Danhier, P; de Cuyper, M; Gallez, B; Gallo, J; Garcia Ribeiro, RS; Gsell, W; Himmelreich, U; Manshian, BB; Soenen, SJ | 1 |
| Lin, HH; Tjong, WY | 1 |
| Attipoe, L; Ballinger, J; Chaabo, K; Cook, G; Cope, AP; Garrood, T; Hassan, FU; Morrison, M; Shivapatham, D; Wajed, J | 1 |
| Dai, S; Hu, F; Liu, Y; Meng, T; Qiu, G; Tan, Y; Wen, L; Yu, F; Yuan, H; Zhu, Y | 1 |
| Makowski, L; Olson-Sidford, W; W-Weisel, J | 1 |
| Bauwens, M; Florea, A; Mottaghy, FM | 1 |
| Chen, T; Fu, Y; Gong, T; Song, X; Yang, L; Zhang, Z | 1 |
| Banach, M; Cole, JA; Czaplewska, P; Czerwinski, A; Dobrucki, IT; Dobrucki, LW; Hedhli, J; Hood, L; Imoukhuede, P; Kalinowski, L; Mamer, SB; Płoska, A; Schuelke, M; Sowinski, P | 1 |
| Abbasi, MM; Adli, ADF; Behzadi, R; Farajnia, S; Farajzadeh, D; Jahanban-Esfahlan, R; Javaheri, T; Minofar, B; Monhemi, H; Seidi, K; Zare, P; Zarghami, N | 1 |
| Chen, T; Fang, X; Jiang, W; Yang, F | 1 |
| Aguiar, PC; Barrias, CC; Bidarra, SJ; Pinto, MT; Silva, EA; Torres, AL | 1 |
| Fu, S; Ma, Y; Xu, X; Zhang, S | 1 |
| Lebrun, R; Loret, EP; Luis, J; Mansuelle, P; Nuccio, C; Villard, C; Villard, PH | 1 |
| He, Y; Ji, X; Jiang, A; Song, B; Su, Y; Tang, M; Xu, H; Zhang, L | 1 |
| Buenestado, S; Calvis, C; Gandioso, A; Hernández, JL; Marchán, V; Massaguer, A; Mitjans, F; Rodríguez, V; Ruiz, J; Zamora, A | 1 |
| Battistini, L; Bianchini, F; Calorini, L; Curti, C; D'Errico, G; De Santis, A; Peppicelli, S; Portioli, E; Russo Krauss, I; Sartori, A; Zanardi, F | 1 |
| Chen, H; Li, J; Li, X; Luo, J; Niu, W; Tang, J; Tong, L; Wang, J; Wang, Y; Xiao, Q; Zhong, L; Zhu, J | 1 |
| Aitken, JB; Austin, CJ; Harris, HH; Jolliffe, KA; Rendina, LM; Sheridan, EJ; Vogt, S | 1 |
| Hu, GQ; Hu, GY; Liu, C; Liu, DB; Long, GX; Mei, Q; Qiu, H; Wang, JF | 1 |
| Kim, IS; Kim, S; Nam, JO; Son, HN | 1 |
| Li, Y; Shen, Y; Wang, A; Wang, F; Wang, S; Xie, T | 1 |
| Barui, S; Chaudhuri, A; Mondal, G; Saha, S | 1 |
| Chen, X; Huang, P; Liu, G; Lu, G; Ma, Y; Nie, L; Rong, P; Wang, S; Wang, X | 1 |
| Abiraj, K; Boerman, OC; Bussink, J; Frielink, C; Oyen, WJ; Terry, SY; van Dijk, LK | 1 |
| Brandt-Larsen, M; El-Ali, HH; Kjaer, A; Madsen, J; Myschetzky, R; Oxboel, J; Schjoeth-Eskesen, C | 1 |
| Hui, T; Rittling, SR; Warot, GA; Wejse, PL; Yagiz, K | 1 |
| Cao, S; Gao, H; Jiang, X; Xiong, Y; Yang, Z; Zhang, S | 1 |
| Chen, K; Kang, F; Li, G; Liang, W; Ma, X; Shao, Y; Wang, J; Yang, W; Zong, S | 1 |
| Fan, D; Jia, B; Jin, Z; Liu, X; Liu, Z; Shi, J; Sun, Y; Wang, F; Zhao, H; Zhu, Z | 1 |
| Barnucz, E; Braun, F; Fani, M; Lassmann, S; Maecke, HR; Rylova, SN; Weber, WA; Werner, M | 1 |
| Faintuch, BL; Oliveira, EA | 1 |
| Bouziotis, P; Fragogeorgi, EA; Kagadis, GC; Karnabatidis, D; Loudos, G; Palamaris, L; Paravatou-Petsotas, M; Psimadas, D; Tsiapa, I; Varvarigou, AD; Xanthopoulos, S | 1 |
| Epple, M; Gräfe, S; Haedicke, K; Hilger, I; Kozlova, D; Teichgräber, U | 1 |
| Andreucci, E; Bianchini, F; Bottoncetti, A; Calorini, L; Fabbrizzi, P; Guarna, A; Menchi, G; Passeri, A; Pupi, A; Raspanti, S; Trabocchi, A | 1 |
| Chen, G; Cordie, T; Eliceiri, KW; Gong, S; Vokoun, C; Wang, L | 1 |
| Akhtar, AM; Allen, D; Chen, X; Choudhury, RP; Hamilton, A; Jefferson, A; Larkin, JR; Melemenidis, S; Muschel, RJ; Perez-Balderas, F; Ruparelia, N; Sibson, NR; Smart, SC; Xie, J | 1 |
| Gao, H; He, Q; Liu, Y; Mei, L; Qiu, Y; Shi, K; Xu, C; Yang, Y; Yu, Q; Zhang, Q; Zhang, Z | 1 |
| Chakraborty, S; Chakravarty, R; Dash, A | 1 |
| Cai, J; Jiang, J; Li, Q; Wu, H; Xu, H | 1 |
| Buchpiguel, CA; Carneiro, CG; de Oliveira, ÉA; Faintuch, BL; Faria, DP; Fonoff, ET; Garcez, AT; Martinez, RCR; Moro, AM; Pagano, RL; Targino, RC | 1 |
| Law, WC; Lin, G; Liu, L; Yin, F; Yong, KT | 1 |
| Chen, H; Chen, X; Niu, G; Wu, H | 1 |
| Cai, J; Cheng, D; Li, X; Liu, S; Shi, H; Su, H; Yang, Y; Zhang, C; Zhang, J; Zhang, L; Zhang, Y | 1 |
| Hu, Q; Kang, LK; Wang, T; Wang, XY; Wei, HM; Wen, ZH; Xu, CM | 1 |
| Feng, D; Li, L; Li, Y; Li, Z; Sheng, J; Wang, A; Wang, F; Yin, F; Zhang, X | 1 |
| Jung, JH; Kim, SE; Lee, BC; Lee, MS; Park, HS; Yoo, JS | 1 |
| Hu, L; Wang, J; Wang, Y; Xu, H | 1 |
| Eo, JS; Jeong, JM | 1 |
| Dalman, RL; Douglas, T; Iida, Y; Kitagawa, T; Kosuge, H; McConnell, MV; Uchida, M | 1 |
| Adem, A; Basu, I; Claros, CS; Gorecka, J; Guha, C; Healy, N; Kabarriti, R; Liu, L; Maggi, E; Quinn, TJ; Sara, A; Scandiuzzi, L; Yuan, Z | 1 |
| Arosio, D; Battistini, L; Bianchini, F; Calorini, L; Portioli, E; Pupi, A; Sartori, A; Vacondio, F; Zanardi, F | 1 |
| Akhtari, M; de Oliveira, EA; Faintuch, BL; Guo, L; Lazovic, J; Pope, W; Soto, H | 1 |
| Barnes, LA; Cheresh, DA; Lutu-Fuga, K; Majeti, BK; Makale, M; Murphy, EA; Weis, SM; Wrasidlo, W | 1 |
| Caruthers, SD; Lanza, GM; Robertson, JD; Schmieder, AH; Wickline, SA; Williams, TA; Zhang, H | 1 |
| Griffioen, AW; Mulder, WJ; Nicolay, K; Reutelingsperger, CP; Strijkers, GJ; van der Schaft, DW; van Tilborg, GA | 1 |
| Castermans, K; Chin, PT; Fayad, ZA; Griffioen, AW; Kaijzel, EL; Löwik, CW; Mulder, WJ; Nicolay, K; Oude Egbrink, MG; Que, I; Storm, G; Strijkers, GJ; van Beijnum, JR | 1 |
| Du, X; Huo, T; Li, X; Liu, X; Zhang, S | 1 |
| Decristoforo, C; Haubner, R | 1 |
| Da Violante, G; Gourlaouen, M; Hart, IR; Hodivala-Dilke, KM; Jones, DT; Jones, MC; Kostourou, V; Norman, JC; Perron-Sierra, F; Reynolds, AR; Robinson, SD; Salih, M; Saunders, G; Silva, RG; Tucker, GC; Watson, AR; Welti, JC | 1 |
| Boerman, OC; Oyen, WJ; Ruers, TJ; Stollman, TH | 1 |
| Cai, W; Cao, F; Chen, K; Chen, X; Lee, A; Li, Z; Liu, Z; Wang, H; Wu, JC | 1 |
| Achilefu, S; Anderson, CJ; Lewis, JS; Wadas, TJ; Wei, L; Welch, MJ; Ye, Y | 1 |
| Arap, W; Hajitou, A; Hanna, E; Henry, C; Kachala, S; Khanna, C; Leblanc, A; Libutti, SK; Mazcko, C; Newman, S; Paoloni, MC; Pasqualini, R; Sorenmo, K; Tandle, A; Thamm, D; Vail, D | 1 |
| Ballmer-Hofer, K; Cohrs, S; Fischer, E; Friedli, A; Grünberg, J; Novak-Hofer, I; Schibli, R; Schubiger, PA | 1 |
| Chen, X; Li, ZB | 1 |
| McParland, BJ; Oulie, I; Roed, L; Skotland, T | 1 |
| Wang, J; Wang, X; Wang, Y; Yang, S; Zhang, Q; Zhang, X; Zhang, Y | 1 |
| Aikawa, R; Dean, J; Dobrucki, LW; Gavin, M; Kalinowski, L; Mendizabal, M; Sen, S; Sinusas, AJ; Tsutsumi, Y | 1 |
| Boerman, OC; Dijkgraaf, I | 1 |
| Chen, W; Cormode, DP; Fayad, ZA; Fisher, EA; Griffioen, AW; Jarzyna, PA; Klink, A; Mulder, WJ; Nguyen, VA; Randolph, GJ; van Tilborg, GA | 1 |
| Hiki, S; Kano, MR; Kataoka, K; Koyama, H; Miyata, K; Miyazono, K; Nishiyama, N; Oba, M; Vachutinsky, Y | 1 |
| Byrne, AT; Fens, MH; Gaillard, CA; Pelgrim, RC; Schiffelers, RM; Storm, G; Ultee, A; van Solinge, WW | 1 |
| Cochran, JR; Deshpande, N; Gambhir, SS; Kimura, RH; Lutz, AM; Willmann, JK | 1 |
| Jia, B; Jin, X; Li, F; Liu, S; Liu, Z; Shi, J; Wang, F; Zhao, H | 1 |
| Bianchini, F; Bottoncetti, A; Calorini, L; Cini, N; Guarna, A; Menchi, G; Pupi, A; Raspanti, S; Trabocchi, A | 1 |
| Bin, JP; Cai, JJ; Hu, GQ; Liao, WJ; Liu, J; Wu, JF; Xiao, YB; Xie, JJ; Yang, L | 1 |
| Chung, JK; Jeong, JM; Jeong, SY; Ju, CH; Kim, YJ; Lee, BC; Lee, DS; Lee, MC; Lee, YS | 1 |
| Hong, M; Jiang, Y; Pei, Y; Qian, L; Zhang, L; Zhu, S | 1 |
| Eldar-Boock, A; Lupu, R; Miller, K; Sanchis, J; Satchi-Fainaro, R; Vicent, MJ | 1 |
| Guo, FQ; Kang, L; Li, L; Wang, RF; Yan, P; Yang, M; Zhang, CL; Zhang, L | 1 |
| Calcagno, C; Dijk, WJ; Fayad, ZA; Gianella, A; Griffioen, AW; Jarzyna, PA; Kann, B; Mani, V; Mulder, WJ; Ramachandran, S; Storm, G; Tang, J; Thijssen, VL | 1 |
| Cheng, Z; Jiang, H; Liu, H; Liu, S; Xu, Y; Zhang, H | 1 |
| Dalman, RL; Douglas, T; Dua, MM; Iida, Y; Kitagawa, T; Kosuge, H; McConnell, MV; Uchida, M | 1 |
| Li, J; Liu, P; Xu, LX; Yang, K; Zhang, C | 1 |
| Deininger, F; Dumont, RA; Fani, M; Haubner, R; Maecke, HR; Weber, WA | 1 |
| Faintuch, BL; Moro, AM; Nanda, PK; Núñez, EG; Oliveira, ÉA; Smith, CJ | 1 |
| Han, SW; Jeong, JM; Kang, KW; Kim, JH; Kim, TY; Lee, DS; Lee, HY; Lee, JS; Lee, YS | 1 |
| Dayton, PA; Feingold, S; Gessner, RC; Streeter, JE; Tsuruta, J | 1 |
| Lu, X; Wang, RF | 1 |
| Huang, X; Li, W; Li, Y; Liu, Z; Pan, L; Pu, C; Ren, Y; Xu, HM; Yang, Y; Zhang, C | 1 |
| Beer, AJ; Gaertner, FC; Kessler, H; Schwaiger, M; Wester, HJ | 1 |
| Cai, W; He, Z; Jia, Y; Jiang, Y; Li, M; Li, W; Lin, M; Lu, D; Luo, G; Meng, S; Qian, L; Wang, Y; Wu, J; Yang, W; Yang, Y; Zhang, H; Zhang, Q; Zhu, X | 1 |
| Hu, JL; Huang, XF; Li, YB; Pu, CY; Xu, HM; Yang, YJ; Zhang, C; Zheng, H | 1 |
| Chen, X; Guo, N; Huang, X; Lee, S; Lu, G; Mohamedali, KA; Niu, G; Rosenblum, MG; Swierczewska, M; Wang, AY; Xu, H; Zhang, F; Zhu, L | 1 |
| Bianchini, F; Bottoncetti, A; Calorini, L; Cini, N; Guarna, A; Menchi, G; Pupi, A; Raspanti, S; Trabocchi, A; Vanzi, E | 1 |
| Aoki, I; Jo, J; Lin, X; Nakahara, T; Saga, T; Tabata, Y | 1 |
| Chung, JK; Hoigebazar, L; Jeong, JM; Lee, BC; Lee, DS; Lee, MC; Lee, YK; Lee, YS; Yang, BY; Youn, H | 1 |
| Kim, J; Kim, WJ; Namgung, R; Park, J; Singha, K; Son, S; Yun, CO | 1 |
| Boumezbeur, F; Geffroy, F; Giraudeau, C; Le Bihan, D; Lethimonnier, F; Mériaux, S; Port, M; Robert, P; Robic, C; Valette, J | 1 |
| Coll, JL; Feige, JJ; Josserand, V; Keramidas, M | 1 |
| Calcagno, C; Chen, W; Deddens, LH; Dijkhuizen, RM; Fayad, ZA; Gianella, A; Griffioen, AW; Jarzyna, PA; Kann, BH; Mulder, WJ; Ramachandran, S | 1 |
| Hong, S; Im, K; Kang, JH; Kang, M; Lee, J; Lee, TS; Lim, SM; Park, S; Ryu, J; Song, R | 1 |
| Bouziotis, P; Fragogeorgi, E; Kagadis, GC; Loudos, G; Mihailidis, D; Nikiforidis, GC; Psimadas, D; Tsiapa, I; Tsotakos, T; Varvarigou, A; Xanthopoulos, S | 1 |
| Han, SO; Kim, SW; Suh, W; Yu, L | 1 |
| Goldmann, U; Haier, J; Hotz, B; Keilholz, U; Runkel, N | 1 |
| Hill-Bator, A; Opolski, A | 1 |
| Janssen, AP; Kok, RJ; Koning, GA; Molema, G; Schiffelers, RM; Schraa, AJ; Storm, G; ten Hagen, TL | 2 |
| Attardo, G; Bergeron, F; Bowlin, T; Bubenik, M; Chan, L; Gourdeau, H; Grouix, B; Leblond, L; Meerovitch, K; Poirier, C | 1 |
| Kalluri, R; Lively, J; Sudhakar, A; Sugimoto, H; Yang, C; Zeisberg, M | 1 |
| Contino-Pépin, C; Jasseron, S; Maurizis, JC; Pucci, B; Rapp, M | 1 |
| Bading, JR; Bozorgzadeh, MH; Chen, X; Conti, PS; Khankaldyyan, V; Laug, WE; Moats, R; Park, R; Shahinian, AH; Tohme, M | 1 |
| Barton, LB; Burgin, KE; Holmes, LM; Ji, J; Li, J; Wagner, TE; Wei, Y; Yu, X | 1 |
| Lü, L; Ren, F; Wang, JH; Wu, Y; Zhao, BC | 1 |
| Ramakrishnan, S; Yokoyama, Y | 1 |
| Fretz, MM; Koning, GA; Krijger, GC; Storm, G; Woroniecka, U | 1 |
| Akhtar, N; Auerbach, R; Dickerson, EB; Helfand, SC; Lindstrom, MJ; Padilla, ML; Steinberg, H; Wang, ZY | 1 |
| Ghandehari, H; Line, BR; McNeill, E; Mitra, A; Mulholland, J; Nan, A | 1 |
| Asai, T; Oku, N | 1 |
| Bading, JR; Bart, R; Bremner, R; Chen, X; Conti, PS; Hou, Y; Park, R; Sievers, E; Tohme, M | 1 |
| Ansari, AM; Fens, MH; Lu, PY; Mixson, AJ; Molema, G; Scaria, PV; Schiffelers, RM; Storm, G; Tang, Q; Woodle, MC; Xu, J; Zhou, Q | 1 |
| Archimandritis, SC; Fani, M; Psimadas, D; Varvarigou, AD; Xanthopoulos, S; Zikos, C | 1 |
| Ghandehari, H; Line, BR; Mitra, A; Nan, A | 1 |
| Kumar, C; Mitola, S; Presta, M; Ribatti, D; Rusnati, M; Tanghetti, E; Urbinati, C; Waltenberger, J | 1 |
| Bleeker, EJ; Griffioen, AW; Habets, JW; Koning, GA; Mulder, WJ; Nicolay, K; Storm, G; Strijkers, GJ; van der Schaft, DW | 1 |
| Belvisi, L; Carminati, P; Chiarucci, I; Ciucci, A; Efrati, D; Giannini, G; Lombardo, K; Manzoni, L; Marcellini, M; Nico, B; Orlandi, A; Pisano, C; Potenza, D; Presta, M; Ribatti, D; Riccioni, T; Scolastico, C; Stasi, MA; Vesci, L | 1 |
| Baker, JR; Kotlyar, A; Myc, A; Peters, J; Shukla, R; Thomas, TP | 1 |
| Kessler, H; Wester, HJ | 1 |
| Ghandehari, H; Line, BR; Mitra, A; Nan, A; Papadimitriou, JC | 1 |
| Arap, W; Chanthery, YH; Kasman, IM; McDonald, DM; Ozawa, MG; Pasqualini, R; Varner, AS; Yao, VJ | 1 |
| Kok, RJ; Koning, GA; Mastrobattista, E; Molema, G; Schiffelers, RM; Storm, G; ten Hagen, TL; Wauben, MH | 1 |
| Cai, W; Cao, Q; Chen, K; Chen, X; Gambhir, SS; Gheysens, O; Shin, DW; Wang, SX | 1 |
| Schiffelers, RM; Storm, G | 1 |
| Haubner, R | 1 |
| Ahmed, N; Dobler, D; Eboigbodin, KE; Song, L; Thornalley, PJ | 1 |
| Boutillon, M; Casara, PJ; Hickman, JA; Maubant, S; Perron-Sierra, F; Saint-Dizier, D; Tucker, GC; Van Obberghen-Schilling, E | 1 |
| Doi, M; Hirohata, S; Hudson, BG; Kondo, S; Kusachi, S; Kyo, S; Miyoshi, T; Ninomiya, Y; Obika, M; Ogawa, H; Sado, Y; Shiratori, Y; Yonezawa, T | 1 |
| Bock, M; Eisenhut, M; Jugold, M; Kiessling, F; Lammers, T; Morgenstern, B; Mueller, MM; Semmler, W; Woenne, EC; Zentgraf, H; Zhang, C | 1 |
| Feng, Y; Jeong, EK; Ke, T; Lu, ZR; Parker, DL; Wang, X | 1 |
| Barnés, CM; Barnes, KR; Haskel, A; Lippard, SJ; Mukhopadhyay, S; Short, SM | 1 |
| Cai, W; Chen, K; Chen, X; Gambhir, SS; Li, ZB | 1 |
| Markland, FS; Ramu, S; Swenson, S | 1 |
| Hustvedt, SO; Knüttel, T; Oulie, I; Roed, L; Skotland, T; Toft, KG | 1 |
| Bao, S; Centeno, B; Cheng, AW; Datto, MB; Jiang, S; Lin, F; Ma, C; Radiloff, DR; Rong, Y; Wang, XF; Yeatman, TJ | 1 |
| Chan Kwon, I; Chi, DY; Choi, K; Kang, E; Kim, IS; Kim, JH; Kim, K; Kim, YS; Lee, S; Nam, HY; Park, JH; Park, K; Park, RW | 1 |
| Chang, YS; Cheon, GJ; Chung, JK; Hong, MK; Jeong, JM; Kim, YJ; Lee, DS; Lee, MC; Lee, YS | 1 |
| Cao, L; Du, P; Hua, ZC; Huang, QL; Jiang, SH; Jin, GH | 1 |
| Nakashima, Y; Sueishi, K; Takei, A; Tashiro, Y | 1 |
| Cheresh, DA; Varner, JA | 1 |
| Koivunen, E; Pasqualini, R; Ruoslahti, E | 1 |
| Barillari, G; Cafaro, A; Colombini, S; Ensoli, B; Fiorelli, V; Manzari, V; Modesti, A; Nair, BC; Samaniego, F; Sgadari, C; Stürzl, M | 1 |
| Kang, IC; Kim, DS; Lee, YD | 1 |
| Burke, PA; DeNardo, GL; DeNardo, SJ; Goodman, SL; Jonczyk, A; Kroger, LA; Lamborn, KR; Leigh, BR; Matzku, S; Miers, LA; O'Donnell, RT | 1 |
| Colorado, PC; Kalluri, R; Maeshima, Y | 1 |
| Boger, DL; Cheresh, DA; Goldberg, J; Kessler, T; Silletti, S | 1 |
| Burkhart, F; Goodman, SL; Haubner, R; Kessler, H; Schwaiger, M; Senekowitsch-Schmidtke, R; Weber, W; Wester, HJ | 1 |
| Brüsselbach, S; Fahr, A; Müller, K; Müller, R; Nahde, T | 1 |
| Armstrong, L; Kumar, CC; Liu, M; Malkowski, M; Nechuta, T; Neustadt, B; Presta, M; Smith, EM; Tanghetti, E; Varner, J; Yaremko, B; Yin, Z | 1 |
| Bretzel, RG; Brownlee, M; Chavakis, E; Hammes, HP; Linn, T; Preissner, KT; Riecke, B | 1 |
| Gao, G; Kaufman, PL; Ma, JX; Saunders, RA; Zhang, D | 1 |
| Doi, R; Fujii, N; Fujimoto, K; Hosotani, R; Ida, J; Imamura, M; Kawaguchi, M; Koizumi, M; Masui, T; Nakajima, S; Ohishi, S; Toyoda, E; Tsuji, S; Tulachan, SS; Wada, M | 1 |
| Borges, E; Bredesen, DE; Ellerby, HM; Firestein, GS; Gerlag, DM; Pasqualini, R; Ruoslahti, E; Tak, PP | 1 |
| Buerkle, MA; Dellian, M; Jonczyk, A; Messmer, K; Pahernik, SA; Sutter, A | 1 |
| Bretzel, RG; Brownlee, M; Chavakis, E; Hammes, HP; Lin, J; Linn, T; Preissner, KT; Riecke, B | 1 |
18 review(s) available for arginyl-glycyl-aspartic acid and Angiogenesis, Pathologic
| Article | Year |
|---|---|
RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy.
Topics: Dendrimers; Humans; Nanomedicine; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2021 |
Biological and Clinical Consequences of Integrin Binding via a Rogue RGD Motif in the SARS CoV-2 Spike Protein.
Topics: Blood Coagulation Disorders; COVID-19; Humans; Integrins; Neovascularization, Pathologic; Oligopeptides; Protein Binding; Receptors, Virus; SARS-CoV-2; Signal Transduction; Spike Glycoprotein, Coronavirus; Virus Internalization | 2021 |
Molecular Imaging of Angiogenesis in Oncology: Current Preclinical and Clinical Status.
Topics: Animals; Biomarkers, Tumor; Cell Hypoxia; Glucose; Humans; Integrins; Matrix Metalloproteinases; Medical Oncology; Molecular Imaging; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Tomography, Emission-Computed, Single-Photon; Vascular Endothelial Growth Factor A | 2021 |
RGD peptide-based non-viral gene delivery vectors targeting integrin α
Topics: Animals; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrin alphaVbeta3; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2019 |
The functions and applications of RGD in tumor therapy and tissue engineering.
Topics: Animals; Biomimetic Materials; Drug Delivery Systems; Gene Transfer Techniques; Humans; Integrins; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Tissue Engineering | 2013 |
Molecular Imaging of Breast Cancer: Role of RGD Peptides.
Topics: Animals; Breast; Breast Neoplasms; Female; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Molecular Imaging; Molecular Probes; Multimodal Imaging; Neovascularization, Pathologic; Oligopeptides; Optical Imaging; Positron-Emission Tomography; Tomography, Emission-Computed, Single-Photon; Ultrasonography, Mammary | 2015 |
Clinical Application of Radiolabeled RGD Peptides for PET Imaging of Integrin αvβ3.
Topics: Animals; Clinical Trials as Topic; Humans; Integrin alphaVbeta3; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radioisotopes; Staining and Labeling | 2016 |
Angiogenesis Imaging Using (68)Ga-RGD PET/CT: Therapeutic Implications.
Topics: Animals; Gallium Radioisotopes; Humans; Neovascularization, Pathologic; Neovascularization, Physiologic; Oligopeptides; Positron Emission Tomography Computed Tomography; Treatment Outcome | 2016 |
Radiolabelled RGD peptides and peptidomimetics for tumour targeting.
Topics: Humans; Integrins; Molecular Mimicry; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2009 |
New targeted probes for radioimaging of angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antigens, Surface; Biomarkers, Tumor; Extracellular Matrix Proteins; Glutamate Carboxypeptidase II; Humans; Integrin alphaVbeta3; Matrix Metalloproteinases; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Radiopharmaceuticals; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A | 2009 |
Radionuclide imaging of tumor angiogenesis.
Topics: Alternative Splicing; Angiogenesis Inhibitors; Animals; Endothelium, Vascular; Fluorodeoxyglucose F18; Humans; Indium Radioisotopes; Integrin alphaVbeta3; Magnetic Resonance Imaging; Matrix Metalloproteinases; Mice; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Receptors, Immunologic; Receptors, Peptide; Receptors, Vascular Endothelial Growth Factor | 2009 |
A concise review of current radiopharmaceuticals in tumor angiogenesis imaging.
Topics: Amino Acid Sequence; Animals; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon | 2012 |
Radiolabelled RGD peptides for imaging and therapy.
Topics: Angiogenesis Inhibitors; Copper Radioisotopes; Galactose; Gallium Radioisotopes; Humans; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Peptides; Peptides, Cyclic; Polyethylene Glycols; Radiopharmaceuticals; Technetium; Tomography, Emission-Computed, Single-Photon | 2012 |
A review of RGD-functionalized nonviral gene delivery vectors for cancer therapy.
Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Endothelium; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Polyethylene Glycols | 2012 |
[Biological activity of synthetic analogs of laminin active sequences: YIGSR, RGD, SIKVAV].
Topics: Animals; Antineoplastic Agents; Humans; Laminin; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Neoplastic Processes; Neovascularization, Pathologic; Oligopeptides; Platelet Aggregation; Thrombosis | 2002 |
Alphavbeta3-integrin imaging: a new approach to characterise angiogenesis?
Topics: Animals; Humans; Image Processing, Computer-Assisted; Integrin alphaVbeta3; Melanoma; Mice; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radioisotopes | 2006 |
Anti-angiogenesis and RGD-containing snake venom disintegrins.
Topics: Angiogenesis Inhibitors; Animals; Disintegrins; Humans; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Snake Venoms | 2007 |
Tumor angiogenesis and the role of vascular cell integrin alphavbeta3.
Topics: Adult; Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion Molecules; Cell Transformation, Neoplastic; Child; Clinical Trials, Phase II as Topic; Endothelial Growth Factors; Extracellular Matrix Proteins; Eye Diseases; Female; Fibroblast Growth Factors; Humans; Inflammation; Lymphokines; Male; Metalloendopeptidases; Neoplasm Proteins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Receptors, Vitronectin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1996 |
3 trial(s) available for arginyl-glycyl-aspartic acid and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Launching a novel preclinical infrastructure: comparative oncology trials consortium directed therapeutic targeting of TNFalpha to cancer vasculature.
Topics: Adenoviridae; Animals; Dogs; Genetic Therapy; Genetic Vectors; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Treatment Outcome; Tumor Necrosis Factor-alpha | 2009 |
Human urinary excretion of NC100692, an RGD-peptide for imaging angiogenesis.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Freeze Drying; Humans; Male; Mass Spectrometry; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Radiography; Radiopharmaceuticals; Single-Blind Method; Technetium | 2009 |
Topical application of integrin antagonists inhibits proliferative retinopathy.
Topics: Adhesiveness; Administration, Topical; Animals; Diabetic Retinopathy; Hypoxia; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oligopeptides; Ophthalmic Solutions; Receptors, Vitronectin; Retina | 2001 |
146 other study(ies) available for arginyl-glycyl-aspartic acid and Angiogenesis, Pathologic
| Article | Year |
|---|---|
Comparison of a New
Topics: Animals; CD146 Antigen; Disease Models, Animal; Fibrosis; Fluorodeoxyglucose F18; Gallium Radioisotopes; Integrin alphaVbeta3; Male; Mice; Myocardial Infarction; Myocardium; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals | 2021 |
Targeting tumor cells and neovascularization using RGD-functionalized magnetoliposomes.
Topics: Animals; Cell Line, Tumor; Dynamic Light Scattering; Female; Humans; Integrin alphaVbeta3; Liposomes; Magnetic Phenomena; Magnetic Resonance Imaging; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Optical Imaging; Xenograft Model Antitumor Assays | 2019 |
The role of the RGD motif in CD97/ADGRE5-and EMR2/ADGRE2-modulated tumor angiogenesis.
Topics: Amino Acid Motifs; Animals; Antigens, CD; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chick Embryo; Culture Media, Conditioned; Human Umbilical Vein Endothelial Cells; Humans; Matrix Metalloproteinase 9; Membrane Proteins; Neovascularization, Pathologic; Oligopeptides; Receptors, G-Protein-Coupled; Vascular Endothelial Growth Factor A | 2019 |
Imaging neoangiogenesis in rheumatoid arthritis (INIRA): whole-body synovial uptake of a
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Neovascularization, Pathologic; Oligopeptides; Organotechnetium Compounds; Proof of Concept Study; Radioactive Tracers; Reproducibility of Results; Synovial Membrane; Ultrasonography, Doppler | 2020 |
Enhancing Drug Delivery for Overcoming Angiogenesis and Improving the Phototherapy Efficacy of Glioblastoma by ICG-Loaded Glycolipid-Like Micelles.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Endothelial Cells; Glioblastoma; Glycolipids; Humans; Indocyanine Green; Mice, Nude; Micelles; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Photosensitizing Agents; Phototherapy; Tissue Distribution; Xenograft Model Antitumor Assays | 2020 |
nRGD modified lycobetaine and octreotide combination delivery system to overcome multiple barriers and enhance anti-glioma efficacy.
Topics: Amaryllidaceae Alkaloids; Animals; Antineoplastic Agents, Hormonal; Cell Proliferation; Central Nervous System Neoplasms; Drug Delivery Systems; Glioma; Indolizines; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neovascularization, Pathologic; Octreotide; Oligopeptides; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured | 2017 |
Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a Dimeric-cRGD Peptide for Targeted Imaging of α
Topics: Animals; Cell Line, Tumor; Copper Radioisotopes; Dimerization; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Kidney; Mice; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography; Rats; Tissue Distribution | 2017 |
RGD delivery of truncated coagulase to tumor vasculature affords local thrombotic activity to induce infarction of tumors in mice.
Topics: Animals; Bacterial Proteins; Cell Line, Tumor; Cells, Cultured; Coagulase; Humans; Infarction; Mice, Inbred C57BL; Mice, Nude; Mutation; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Recombinant Fusion Proteins; Thrombosis; Tumor Burden; Xenograft Model Antitumor Assays | 2017 |
Bioresponsive cancer-targeted polysaccharide nanosystem to inhibit angiogenesis.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Movement; Chick Embryo; Chorioallantoic Membrane; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen-Ion Concentration; Nanostructures; Neovascularization, Pathologic; Oligopeptides; Polysaccharides; Vascular Endothelial Growth Factor A | 2017 |
Guiding morphogenesis in cell-instructive microgels for therapeutic angiogenesis.
Topics: Alginates; Animals; Cell Movement; Cellular Microenvironment; Chick Embryo; Endothelial Cells; Extracellular Matrix; Gels; Glucuronic Acid; Hexuronic Acids; Humans; Intercellular Signaling Peptides and Proteins; Mesenchymal Stem Cells; Morphogenesis; Neovascularization, Pathologic; Neovascularization, Physiologic; Oligopeptides; Oxygen | 2018 |
A Low Molecular Weight Protein from the Sea Anemone
Topics: Amino Acid Sequence; Angiogenesis Inhibitors; Animals; Cell Proliferation; Cells, Cultured; Circular Dichroism; Humans; Molecular Weight; Neovascularization, Pathologic; Oligopeptides; Proteins; Sea Anemones; Vascular Endothelial Growth Factor A | 2018 |
Photostable and Biocompatible Fluorescent Silicon Nanoparticles-Based Theranostic Probes for Simultaneous Imaging and Treatment of Ocular Neovascularization.
Topics: Animals; Biocompatible Materials; Cell Line; Drug Stability; Fluorescent Dyes; Humans; MCF-7 Cells; Mice; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Optical Imaging; Retina; Silicon; Theranostic Nanomedicine; Time Factors; Tissue Distribution | 2018 |
Toward Angiogenesis Inhibitors Based on the Conjugation of Organometallic Platinum(II) Complexes to RGD Peptides.
Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Human Umbilical Vein Endothelial Cells; Humans; Molecular Structure; Neovascularization, Pathologic; Oligopeptides; Organoplatinum Compounds; Structure-Activity Relationship | 2018 |
Integrin-targeted AmpRGD sunitinib liposomes as integrated antiangiogenic tools.
Topics: Angiogenesis Inhibitors; Animals; Cell Adhesion; Endothelial Progenitor Cells; Humans; Infant, Newborn; Integrin alphaVbeta3; Lipids; Liposomes; Mice; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Phospholipids; Phosphorylation; Proline; Sunitinib; Vascular Endothelial Growth Factor Receptor-2; Vitronectin | 2019 |
cRGD-functionalized nanoparticles for combination therapy of anti-endothelium dependent vessels and anti-vasculogenic mimicry to inhibit the proliferation of ovarian cancer.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Chick Embryo; Endothelium, Vascular; Female; Folic Acid; Heparin; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Ovarian Neoplasms; Xenograft Model Antitumor Assays | 2019 |
Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells.
Topics: Animals; Bromine; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Spectrometry, X-Ray Emission; Tumor Cells, Cultured | 2013 |
Specific targeting of angiogenesis in lung cancer with RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a 4.7T magnetic resonance scanner.
Topics: Animals; Cells, Cultured; Dextrans; Humans; Integrin alphaVbeta3; Lung Neoplasms; Magnetic Resonance Imaging; Magnetite Nanoparticles; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oligopeptides | 2013 |
Multiple FAS1 domains and the RGD motif of TGFBI act cooperatively to bind αvβ3 integrin, leading to anti-angiogenic and anti-tumor effects.
Topics: Animals; Antibodies, Monoclonal; Antibody Formation; Blotting, Western; Carcinoma, Lewis Lung; Cell Proliferation; Endothelium, Vascular; Extracellular Matrix Proteins; fas Receptor; Humans; Immunoenzyme Techniques; Integrin alphaVbeta3; Male; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Transforming Growth Factor beta; Tumor Cells, Cultured | 2013 |
Tumor growth inhibition through targeting liposomally bound curcumin to tumor vasculature.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Drug Delivery Systems; Female; Human Umbilical Vein Endothelial Cells; Humans; Liposomes; Mice; Mice, Inbred C57BL; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2013 |
In vivo volumetric photoacoustic molecular angiography and therapeutic monitoring with targeted plasmonic nanostars.
Topics: Angiography; Animals; Cell Line, Tumor; Contrast Media; Glioma; Gold; Humans; Hyperthermia, Induced; Imaging, Three-Dimensional; Integrin alphaVbeta3; Metal Nanoparticles; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Phantoms, Imaging; Photoacoustic Techniques | 2014 |
Imaging integrin αvβ3 on blood vessels with 111In-RGD2 in head and neck tumor xenografts.
Topics: Animals; Blood Vessels; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Head and Neck Neoplasms; Immunohistochemistry; Indium Radioisotopes; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Radiopharmaceuticals; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2014 |
Comparison of two new angiogenesis PET tracers 68Ga-NODAGA-E[c(RGDyK)]2 and (64)Cu-NODAGA-E[c(RGDyK)]2; in vivo imaging studies in human xenograft tumors.
Topics: Acetates; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Copper Radioisotopes; Female; Gallium Radioisotopes; Glioblastoma; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiochemistry; Radiometry; Tissue Distribution; Tomography, X-Ray Computed | 2014 |
Suppression of tumour growth by orally administered osteopontin is accompanied by alterations in tumour blood vessels.
Topics: Administration, Oral; Animals; Binding Sites; Blood Vessels; Cattle; Cell Growth Processes; Female; Integrin alpha Chains; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Osteopontin; Peptides; Protein Binding | 2014 |
RGD and interleukin-13 peptide functionalized nanoparticles for enhanced glioblastoma cells and neovasculature dual targeting delivery and elevated tumor penetration.
Topics: Animals; Blood-Brain Barrier; Blotting, Western; Brain Neoplasms; Cell Membrane Permeability; Cell Proliferation; Cells, Cultured; Drug Delivery Systems; Endocytosis; Flow Cytometry; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Interleukin-13; Interleukin-13 Receptor alpha2 Subunit; Mice; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Pathologic; Oligopeptides | 2014 |
A direct comparison of tumor angiogenesis with ⁶⁸Ga-labeled NGR and RGD peptides in HT-1080 tumor xenografts using microPET imaging.
Topics: Adenocarcinoma; Animals; Biological Transport; Cell Line, Tumor; Drug Stability; Female; Fibrosarcoma; Gallium Radioisotopes; Humans; Hydrophobic and Hydrophilic Interactions; Mice, Nude; Molecular Imaging; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Renal Elimination; Tissue Distribution; Xenograft Model Antitumor Assays | 2014 |
PET imaging of neovascularization with (68)Ga-3PRGD2 for assessing tumor early response to Endostar antiangiogenic therapy.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Lewis Lung; Cell Line, Tumor; Endostatins; Female; Gallium Radioisotopes; Humans; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiopharmaceuticals; Recombinant Proteins; Time Factors | 2014 |
Does imaging αvβ3 integrin expression with PET detect changes in angiogenesis during bevacizumab therapy?
Topics: Acetates; Algorithms; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Carcinoma, Squamous Cell; Cell Line, Tumor; Female; Gallium Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Microcirculation; Necrosis; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides; Permeability; Positron-Emission Tomography; Time Factors | 2014 |
Radiolabeling and biological evaluation of the GX1 and RGD-GX1 peptide sequence for angiogenesis targeting.
Topics: Amino Acid Sequence; Animals; Blood Proteins; Chelating Agents; Dimerization; Drug Stability; Humans; Hydrazines; Isotope Labeling; Mice; Mice, Inbred BALB C; Molecular Imaging; Neovascularization, Pathologic; Nicotinic Acids; Oligopeptides; Radiochemistry; Technetium; Tissue Distribution | 2015 |
Evaluation of ανβ3-mediated tumor expression with a 99mTc-labeled ornithine-modified RGD derivative during glioblastoma growth in vivo.
Topics: Animals; Cell Line, Tumor; Glioblastoma; Humans; Integrin alphaVbeta3; Isotope Labeling; Mice; Mice, SCID; Neovascularization, Pathologic; Oligopeptides; Ornithine; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Tissue Distribution | 2014 |
Multifunctional calcium phosphate nanoparticles for combining near-infrared fluorescence imaging and photodynamic therapy.
Topics: Animals; Apoptosis; Calcium Phosphates; Cell Line, Tumor; Endocytosis; Female; Fluorescence; Humans; Infrared Rays; Light; Luminescent Measurements; Mice, Nude; Molecular Imaging; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Photochemotherapy; Scattering, Radiation; Tissue Distribution | 2015 |
Radiosynthesis and micro-SPECT analysis of triazole-based RGD integrin ligands as non-peptide molecular imaging probes for angiogenesis.
Topics: Animals; Heterografts; Humans; Integrins; Ligands; Melanoma; Mice; Models, Molecular; Molecular Probes; Neovascularization, Pathologic; Oligopeptides; Tomography, Emission-Computed, Single-Photon; Triazoles | 2015 |
Multi-functional self-fluorescent unimolecular micelles for tumor-targeted drug delivery and bioimaging.
Topics: Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Humans; Hydrodynamics; Hydrogen-Ion Concentration; Integrin alphaVbeta3; Magnetic Resonance Spectroscopy; Micelles; Microscopy, Fluorescence; Neovascularization, Pathologic; Oligopeptides; Peptides; Photons; Polyethylene Glycols; Polymers; Spectroscopy, Fourier Transform Infrared | 2015 |
Molecular magnetic resonance imaging of angiogenesis in vivo using polyvalent cyclic RGD-iron oxide microparticle conjugates.
Topics: Animals; Cells, Cultured; Endothelial Cells; Female; Ferric Compounds; Humans; Magnetic Resonance Imaging; Mice, Inbred C57BL; Microspheres; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Protein Binding; Radiography | 2015 |
Multifunctional Tandem Peptide Modified Paclitaxel-Loaded Liposomes for the Treatment of Vasculogenic Mimicry and Cancer Stem Cells in Malignant Glioma.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Glioma; Liposomes; Mice, Inbred BALB C; Neoplastic Stem Cells; Neovascularization, Pathologic; Oligopeptides; Paclitaxel; Treatment Outcome | 2015 |
RGD mimetics γ-AApeptides and methods of use (US 20,140,004,039 A1): a patent evaluation.
Topics: Animals; Antineoplastic Agents; Drug Design; Humans; Integrin alphaVbeta3; Mice; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Patents as Topic; Positron-Emission Tomography | 2016 |
Evaluation of GX1 and RGD-GX1 peptides as new radiotracers for angiogenesis evaluation in experimental glioma models.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Glioma; Humans; Mice; Mice, SCID; Neovascularization, Pathologic; Oligopeptides; Radiopharmaceuticals; Technetium; Tomography, Emission-Computed, Single-Photon | 2016 |
Near-infrared fluorescent peptide probes for imaging of tumor in vivo and their biotoxicity evaluation.
Topics: Animals; Carbocyanines; Female; Fluorescent Dyes; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Optical Imaging; Pancreas; Pancreatic Neoplasms; Spectroscopy, Near-Infrared | 2016 |
Tumor Angiogenesis Targeted Radiosensitization Therapy Using Gold Nanoprobes Guided by MRI/SPECT Imaging.
Topics: Animals; Cell Death; Cell Line, Tumor; Gadolinium; Gold; Humans; Immunohistochemistry; Integrin alphaVbeta3; Magnetic Resonance Imaging; Metal Nanoparticles; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Radiation Tolerance; Subcellular Fractions; Technetium; Tissue Distribution; Tomography, Emission-Computed, Single-Photon | 2016 |
RGD-Targeted Ultrasound Contrast Agent for Longitudinal Assessment of Hep-2 Tumor Angiogenesis In Vivo.
Topics: Acoustics; Animals; Avidin; Binding, Competitive; Biotin; Cell Adhesion; Cell Line; Cell Line, Tumor; Contrast Media; Disease Models, Animal; Endothelial Cells; Female; Humans; Integrin alphaVbeta3; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Microbubbles; Microscopy, Fluorescence; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides; Protein Binding; Ultrasonography; Video Recording | 2016 |
Tat PTD-Endostatin-RGD: A novel protein with anti-angiogenesis effect in retina via eye drops.
Topics: Animals; Blood-Retinal Barrier; Chick Embryo; Chorioallantoic Membrane; Diabetic Retinopathy; Endostatins; Humans; Integrin alphaVbeta3; Mice; Neovascularization, Pathologic; Oligopeptides; Ophthalmic Solutions; Rats; Recombinant Fusion Proteins; Retina; Retinal Neovascularization; Retinal Vessels; S-Nitroso-N-Acetylpenicillamine | 2016 |
Identification of Angiogenesis Rich-Viable Myocardium using RGD Dimer based SPECT after Myocardial Infarction.
Topics: Animals; Fluorodeoxyglucose F18; Integrin alphaVbeta3; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Neovascularization, Pathologic; Oligopeptides; Organotechnetium Compounds; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tomography, Emission-Computed, Single-Photon | 2016 |
An integrin αvβ3 antagonistic modified peptide inhibits tumor growth through inhibition of the ERK and AKT signaling pathways.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chick Embryo; Female; Humans; Integrin alphaVbeta3; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Oligonucleotide Array Sequence Analysis; Oligopeptides; Polyethylene Glycols; Polymerase Chain Reaction; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Xenograft Model Antitumor Assays | 2016 |
RGD targeting of human ferritin iron oxide nanoparticles enhances in vivo MRI of vascular inflammation and angiogenesis in experimental carotid disease and abdominal aortic aneurysm.
Topics: Animals; Aortic Aneurysm, Abdominal; Carotid Arteries; Carotid Artery Diseases; Disease Models, Animal; Ferric Compounds; Ferritins; Inflammation; Magnetic Resonance Imaging; Male; Mice; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Vascular Diseases | 2017 |
Preclinical evaluation of radiation and systemic, RGD-targeted, adeno-associated virus phage-TNF gene therapy in a mouse model of spontaneously metastatic melanoma.
Topics: Animals; Cell Line, Tumor; Combined Modality Therapy; Dependovirus; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Genetic Therapy; Genetic Vectors; Melanoma; Melanoma, Experimental; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Oligopeptides; Radiotherapy; Radiotherapy, Image-Guided; Survival Analysis; Treatment Outcome; Tumor Burden; Tumor Microenvironment; Tumor Necrosis Factor-alpha | 2017 |
Synthesis of Novel c(AmpRGD)-Sunitinib Dual Conjugates as Molecular Tools Targeting the α
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Humans; Indoles; Integrin alphaVbeta3; Mice; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor Receptor-2 | 2017 |
Evaluation of Magnetonanoparticles Conjugated with New Angiogenesis Peptides in Intracranial Glioma Tumors by MRI.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Contrast Media; Glioma; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides | 2017 |
Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Endothelium; Integrin alphaVbeta3; Kidney Neoplasms; Mice; Nanoparticles; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2008 |
Three-dimensional MR mapping of angiogenesis with alpha5beta1(alpha nu beta3)-targeted theranostic nanoparticles in the MDA-MB-435 xenograft mouse model.
Topics: Angiogenesis Inhibitors; Animals; Breast Neoplasms; Cell Adhesion; Contrast Media; Cyclohexanes; Fatty Acids, Unsaturated; Fibronectins; Flow Cytometry; Integrin alphaVbeta3; Magnetic Resonance Angiography; Mice; Microscopy, Confocal; Nanoparticles; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Particle Size; Receptors, Vitronectin; Sesquiterpenes | 2008 |
Improved magnetic resonance molecular imaging of tumor angiogenesis by avidin-induced clearance of nonbound bimodal liposomes.
Topics: Animals; Avidin; Cell Line, Tumor; Endothelium, Vascular; Humans; Integrin alphaVbeta3; Liposomes; Magnetic Resonance Imaging; Melanoma; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Nanoparticles; Neovascularization, Pathologic; Oligopeptides | 2008 |
Molecular imaging of tumor angiogenesis using alphavbeta3-integrin targeted multimodal quantum dots.
Topics: Animals; Chickens; Chorioallantoic Membrane; Diagnostic Imaging; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Microscopy, Fluorescence; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Quantum Dots | 2009 |
Gd-EDDA/HYNIC-RGD as an MR molecular probe imaging integrin alphanubeta3 receptor-expressed tumor-MR molecular imaging of angiogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Contrast Media; Diethylamines; Gadolinium; Humans; Hydrazines; Image Enhancement; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Mice, Nude; Molecular Probe Techniques; Neovascularization, Pathologic; Nicotinic Acids; Oligopeptides; Rats; Reproducibility of Results; Sensitivity and Specificity | 2010 |
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors.
Topics: Angiogenesis Inhibitors; Animals; Disease Models, Animal; Humans; Integrin alphaVbeta3; Lung Neoplasms; Melanoma, Experimental; Mice; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Vascular Endothelial Growth Factor A | 2009 |
Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Copper Radioisotopes; Embryonic Stem Cells; Endothelial Cells; Female; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Organometallic Compounds; Ovarian Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Teratoma; Transplantation, Heterologous | 2009 |
(64)Cu-labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity.
Topics: Animals; Binding, Competitive; Chelating Agents; Dipeptides; Heterocyclic Compounds; Humans; Integrin alphaVbeta3; Male; Melanoma; Mice; Neovascularization, Pathologic; Oligopeptides; Organometallic Compounds; Positron-Emission Tomography; Sarcosine; Staining and Labeling; Tissue Distribution | 2009 |
The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor.
Topics: Angiogenic Proteins; Animals; Antibodies, Monoclonal; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chickens; Chorioallantoic Membrane; Collagen; Drug Combinations; Endothelial Cells; Female; Fibronectins; Humans; Laminin; Neoplasms; Neovascularization, Pathologic; Neural Cell Adhesion Molecule L1; Oligopeptides; Ovarian Neoplasms; Protein Structure, Tertiary; Proteoglycans; Repetitive Sequences, Amino Acid; Solubility; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2009 |
MicroPET, MicroSPECT, and NIR fluorescence imaging of biomolecules in vivo.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Fluorescence; Fluorine Radioisotopes; Glioblastoma; Humans; Infrared Rays; Integrin alphaVbeta3; Mice; Mice, Nude; Molecular Probe Techniques; Molecular Probes; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Technetium; Tomography, Emission-Computed, Single-Photon | 2009 |
RGD-modified polymeric micelles as potential carriers for targeted delivery to integrin-overexpressing tumor vasculature and tumor cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Drug Carriers; Drug Delivery Systems; Endothelium, Vascular; Humans; Integrin alphaVbeta3; Melanoma; Mice; Micelles; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Receptors, Vitronectin; Umbilical Veins | 2009 |
Analysis of angiogenesis induced by local IGF-1 expression after myocardial infarction using microSPECT-CT imaging.
Topics: Animals; Dependovirus; Gene Expression Regulation; Humans; Insulin-Like Growth Factor I; Integrin alphaV; Myocardial Infarction; Neovascularization, Pathologic; Oligopeptides; Rats; Rats, Sprague-Dawley; Technetium; Time Factors; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2010 |
RGD peptide functionalized and reconstituted high-density lipoprotein nanoparticles as a versatile and multimodal tumor targeting molecular imaging probe.
Topics: Animals; Cells, Cultured; Endothelium, Vascular; Humans; Immunoenzyme Techniques; Integrin alphaVbeta3; Lipoproteins, HDL; Macrophages; Magnetic Resonance Imaging; Mice; Mice, Nude; Microscopy, Confocal; Molecular Imaging; Molecular Probes; Nanoparticles; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Phagocytosis; Sarcoma, Ewing; Spectroscopy, Near-Infrared; Tissue Distribution; Umbilical Veins | 2010 |
Antiangiogenic gene therapy of experimental pancreatic tumor by sFlt-1 plasmid DNA carried by RGD-modified crosslinked polyplex micelles.
Topics: Animals; Cell Line, Tumor; Cross-Linking Reagents; DNA; Female; Gene Transfer Techniques; Genetic Therapy; Injections, Intravenous; Lysine; Mice; Mice, Inbred BALB C; Micelles; Microvessels; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Pancreatic Neoplasms; Peptides, Cyclic; Plasmids; Polyethylene Glycols; Polylysine; Reverse Transcriptase Polymerase Chain Reaction; Sulfhydryl Compounds; Transfection; Vascular Endothelial Growth Factor Receptor-1 | 2011 |
Erythrophagocytosis by angiogenic endothelial cells is enhanced by loss of erythrocyte deformability.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Erythrocyte Deformability; Erythrocytes; Flow Cytometry; Glutaral; Humans; Integrin alpha Chains; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Neovascularization, Pathologic; Oligopeptides; Phagocytosis; rac1 GTP-Binding Protein; Surface Properties | 2010 |
Targeted contrast-enhanced ultrasound imaging of tumor angiogenesis with contrast microbubbles conjugated to integrin-binding knottin peptides.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Biomimetic Materials; Cell Adhesion; Cell Line, Tumor; Cell Transformation, Neoplastic; Contrast Media; Drug Design; Female; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Integrin alphaVbeta3; Integrins; Mice; Microbubbles; Molecular Sequence Data; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Reproducibility of Results; Ultrasonography | 2010 |
Tumor uptake of the RGD dimeric probe (99m)Tc-G3-2P4-RGD2 is correlated with integrin αvβ3 expressed on both tumor cells and neovasculature.
Topics: Animals; Dimerization; Female; Fluorescent Dyes; HT29 Cells; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organotechnetium Compounds; Peptides, Cyclic; Tissue Distribution; Tumor Cells, Cultured | 2010 |
Click-chemistry-derived triazole ligands of arginine-glycine-aspartate (RGD) integrins with a broad capacity to inhibit adhesion of melanoma cells and both in vitro and in vivo angiogenesis.
Topics: Alkynes; Angiogenesis Inhibitors; Animals; Azides; Cell Adhesion; Cell Line, Tumor; Drug Screening Assays, Antitumor; Endothelial Cells; Extracellular Matrix Proteins; Humans; Integrin alphaVbeta3; Ligands; Melanoma; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Mimicry; Neovascularization, Pathologic; Oligopeptides; Phenylpropionates; Protein Binding; Radioligand Assay; Receptors, Vitronectin; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2010 |
[Evaluation of tumor angiogenesis using microbubbles conjugated with RGD peptides and contrast enhanced ultrasound].
Topics: Animals; Cell Line, Tumor; Contrast Media; Endothelium, Vascular; Female; Humans; Integrin alphaVbeta3; Liver Neoplasms; Male; Mice; Mice, Nude; Microbubbles; Muscle, Skeletal; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Ultrasonics; Ultrasonography | 2010 |
Development of a ¹⁷⁷Lu-labeled RGD derivative for targeting angiogenesis.
Topics: Animal Structures; Animals; Chelating Agents; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Delivery Systems; Drug Stability; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Kidney; Lutetium; Male; Mice; Mice, Inbred BALB C; Molecular Structure; Neovascularization, Pathologic; Oligopeptides; Radioisotopes; Radiopharmaceuticals; Tissue Distribution | 2010 |
RGD-modified PEG-PAMAM-DOX conjugate: in vitro and in vivo targeting to both tumor neovascular endothelial cells and tumor cells.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Proliferation; Dendrimers; Doxorubicin; Endothelial Cells; Humans; Ligands; Mice; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Polyethylene Glycols | 2011 |
Integrin-assisted drug delivery of nano-scaled polymer therapeutics bearing paclitaxel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cathepsin B; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Humans; Integrins; Mice; Mice, Inbred BALB C; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Paclitaxel; Polyglutamic Acid; Rats; Rats, Wistar | 2011 |
[(131)I labeling and bioactivity evaluation of a novel RGD dimer targeted to integrin αvβ3 receptor].
Topics: Animals; Dimerization; Integrin alphaVbeta3; Iodine Radioisotopes; Isotope Labeling; Melanoma, Experimental; Mice; Neovascularization, Pathologic; Oligopeptides; Radionuclide Imaging | 2011 |
Multifunctional nanoemulsion platform for imaging guided therapy evaluated in experimental cancer.
Topics: Animals; Colonic Neoplasms; Drug Carriers; Emulsions; Glucocorticoids; Lipids; Magnetic Resonance Imaging; Medical Oncology; Mice; Microscopy, Electron, Transmission; Nanomedicine; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Photons; Prednisolone | 2011 |
One-step radiosynthesis of ¹⁸F-AlF-NOTA-RGD₂ for tumor angiogenesis PET imaging.
Topics: Animals; Cell Line, Tumor; Drug Stability; Female; Glioblastoma; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Integrins; Mice; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiochemistry | 2011 |
RGD-conjugated human ferritin nanoparticles for imaging vascular inflammation and angiogenesis in experimental carotid and aortic disease.
Topics: Animals; Aortic Diseases; Carotid Arteries; Carotid Artery Diseases; Cattle; Cells, Cultured; Diagnostic Techniques, Cardiovascular; Disease Models, Animal; Endothelial Cells; Ferritins; Humans; Immunohistochemistry; Inflammation; Macrophages; Male; Mice; Mice, Transgenic; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Protein Binding; Spectrometry, Fluorescence; Spectroscopy, Near-Infrared; Tomography | 2012 |
SPIO-RGD nanoparticles as a molecular targeting probe for imaging tumor angiogenesis using synchrotron radiation.
Topics: Animals; Cell Line, Tumor; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Probes; Nanoparticles; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Synchrotrons | 2011 |
Novel (64)Cu- and (68)Ga-labeled RGD conjugates show improved PET imaging of α(ν)β(3) integrin expression and facile radiosynthesis.
Topics: Animals; Binding, Competitive; Cell Line, Tumor; Chelating Agents; Contrast Media; Copper Radioisotopes; Female; Gallium Radioisotopes; Gene Expression Regulation; Humans; Integrin alphaVbeta3; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Peptides; Positron-Emission Tomography; Temperature; Time Factors | 2011 |
Radiotracers for different angiogenesis receptors in a melanoma model.
Topics: Animals; Disease Models, Animal; Humans; Melanoma; Melanoma, Experimental; Mice; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Polyvinyls; Radioactive Tracers; Radionuclide Imaging; Radiopharmaceuticals; Technetium; Technetium Compounds | 2012 |
Whole-body distribution and radiation dosimetry of (68)Ga-NOTA-RGD, a positron emission tomography agent for angiogenesis imaging.
Topics: Adult; Aged; Female; Gallium Radioisotopes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Radiation Dosage; Radiometry; Radiopharmaceuticals; Tissue Distribution | 2012 |
Assessment of molecular imaging of angiogenesis with three-dimensional ultrasonography.
Topics: Animals; Contrast Media; Fibrosarcoma; Imaging, Three-Dimensional; Immunohistochemistry; Integrin alphaVbeta3; Microbubbles; Molecular Imaging; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Rats; Ultrasonography | 2011 |
In vivo pharmacokinetics, immunogenicity and mechanism of PEGylated antitumor polypeptide.
Topics: Animals; Antibodies; Antineoplastic Agents; Area Under Curve; Cell Line, Tumor; Endostatins; Female; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; Male; Mice; Mice, Inbred BALB C; Necrosis; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Polyethylene Glycols; Protein Binding; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays | 2012 |
Dual function of RGD-modified VEGI-192 for breast cancer treatment.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chickens; Chorioallantoic Membrane; Female; Human Umbilical Vein Endothelial Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oligopeptides; Signal Transduction; Tumor Necrosis Factor Ligand Superfamily Member 15; Xenograft Model Antitumor Assays | 2012 |
RGD-modified endostatin fragments showed an antitumor effect through antiangiogenesis.
Topics: Animals; Antineoplastic Agents; Aorta, Thoracic; Cell Adhesion; Cell Movement; Drug Delivery Systems; Endostatins; Female; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oligopeptides; Rats, Sprague-Dawley | 2012 |
Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles.
Topics: Animals; Cell Line, Tumor; Disease Models, Animal; Female; Ferric Compounds; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Integrin beta3; Magnetic Resonance Imaging; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Platelet Endothelial Cell Adhesion Molecule-1; Staining and Labeling; Vascular Endothelial Growth Factor A | 2012 |
¹²⁵I-radiolabeled morpholine-containing arginine-glycine-aspartate (RGD) ligand of αvβ₃ integrin as a molecular imaging probe for angiogenesis.
Topics: Cell Adhesion; Cell Movement; Human Umbilical Vein Endothelial Cells; Humans; Integrin alphaVbeta3; Iodine Radioisotopes; Ligands; Melanoma; Models, Molecular; Molecular Probes; Morpholines; Multimodal Imaging; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Positron-Emission Tomography; Radiopharmaceuticals; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution; Tomography, X-Ray Computed; Transplantation, Heterologous | 2012 |
Preparation of polymer-based magnetic resonance imaging contrast agent to visualize therapeutic angiogenesis.
Topics: Animals; Contrast Media; Dextrans; Drug Carriers; Gadolinium DTPA; Image Enhancement; Ischemia; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oligopeptides | 2013 |
Nanoparticles modified by encapsulation of ligands with a long alkyl chain to affect multispecific and multimodal imaging.
Topics: Animals; Capsules; Cell Line, Tumor; Female; Humans; Hydrophobic and Hydrophilic Interactions; Lactose; Ligands; Liver; Mannose; Mice; Molecular Imaging; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Polysorbates; Quantum Dots; Radionuclide Imaging; Spleen | 2012 |
19F molecular MR imaging for detection of brain tumor angiogenesis: in vivo validation using targeted PFOB nanoparticles.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Fluorine; Fluorocarbons; Humans; Hydrocarbons, Brominated; Injections; Magnetic Resonance Imaging; Mice; Microscopy, Fluorescence; Molecular Imaging; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Reproducibility of Results; Xenograft Model Antitumor Assays | 2013 |
Noninvasive and quantitative assessment of in vivo angiogenesis using RGD-based fluorescence imaging of subcutaneous sponges.
Topics: Angiogenesis Inhibitors; Angiostatins; Animals; Female; Fibroblast Growth Factor 2; Fluorescence; Mice; Mice, Nude; Molecular Imaging; Neovascularization, Pathologic; Neovascularization, Physiologic; Oligopeptides; Subcutaneous Tissue; Surgical Sponges | 2013 |
Tumor angiogenesis phenotyping by nanoparticle-facilitated magnetic resonance and near-infrared fluorescence molecular imaging.
Topics: Animals; Bone Neoplasms; Colorectal Neoplasms; Contrast Media; Disease Models, Animal; Fluorescence; Humans; Immunoenzyme Techniques; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Molecular Imaging; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Sarcoma, Ewing; Spectroscopy, Near-Infrared | 2012 |
RGD peptide-conjugated multimodal NaGdF4:Yb3+/Er3+ nanophosphors for upconversion luminescence, MR, and PET imaging of tumor angiogenesis.
Topics: Animals; Cell Line, Tumor; Dimerization; Erbium; Feasibility Studies; Fluorides; Gadolinium; Glioblastoma; Humans; Integrin alphaVbeta3; Iodine Radioisotopes; Luminescent Agents; Luminescent Measurements; Magnetic Resonance Imaging; Mice; Molecular Imaging; Nanostructures; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Positron-Emission Tomography; Ytterbium | 2013 |
Biological evaluation of an ornithine-modified (99m)Tc-labeled RGD peptide as an angiogenesis imaging agent.
Topics: Animals; Cell Line, Tumor; Drug Stability; Female; Humans; Isotope Labeling; Magnetic Resonance Imaging; Mice; Neovascularization, Pathologic; Oligopeptides; Ornithine; Quality Control; Rhenium; Technetium; Tomography, Emission-Computed, Single-Photon | 2013 |
An angiogenic, endothelial-cell-targeted polymeric gene carrier.
Topics: Cells, Cultured; Endothelium; Gene Transfer Techniques; Genes, Reporter; Genetic Vectors; Humans; Integrin alphaVbeta3; Integrins; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Neovascularization, Pathologic; Oligopeptides; Peptides; Plasmids; Polymers; Receptors, Vitronectin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transfection | 2002 |
Inhibition of tumor progression and neoangiogenesis using cyclic RGD-peptides in a chemically induced colon carcinoma in rats.
Topics: Animals; Carcinogens; Cell Division; Colonic Neoplasms; Dimethylhydrazines; Disease Progression; Male; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
Peptide-targeted PEG-liposomes in anti-angiogenic therapy.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Lewis Lung; Cells, Cultured; Drug Carriers; Drug Delivery Systems; Endothelium, Vascular; Flow Cytometry; Humans; In Vitro Techniques; Liposomes; Mice; Microscopy, Confocal; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Polyethylene Glycols; Receptors, Vascular Endothelial Growth Factor; Time Factors; Transplants | 2003 |
A novel RGD antagonist that targets both alphavbeta3 and alpha5beta1 induces apoptosis of angiogenic endothelial cells on type I collagen.
Topics: Anoikis; Apoptosis; Cell Adhesion; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Collagen Type I; Endothelium, Vascular; Extracellular Matrix; Guanidines; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Molecular Mimicry; Neovascularization, Pathologic; Oligopeptides; Peptides; Receptors, Immunologic; Sulfonamides; Vitronectin | 2003 |
Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins.
Topics: Amino Acid Sequence; Autoantigens; Binding, Competitive; Cells, Cultured; Collagen; Collagen Type IV; Collagen Type XVIII; Endostatins; Endothelium, Vascular; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alpha5beta1; Integrin alphaVbeta3; MAP Kinase Signaling System; Models, Biological; Molecular Sequence Data; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Protein Binding; Protein-Tyrosine Kinases; Recombinant Proteins; Vitronectin | 2003 |
In vitro and in vivo evaluations of THAM derived telomers bearing RGD and Ara-C for tumour neovasculature targeting.
Topics: Acrylates; Animals; Cell Division; Cell Line, Tumor; Cytarabine; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Male; Methylamines; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oligopeptides; Prodrugs; Tissue Distribution | 2003 |
18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Feasibility Studies; Female; Fluorine Radioisotopes; Glioblastoma; Humans; Integrin alphaVbeta3; Metabolic Clearance Rate; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Organ Specificity; Pilot Projects; Radionuclide Imaging; Radiopharmaceuticals; Tissue Distribution | 2004 |
Fusion protein from RGD peptide and Fc fragment of mouse immunoglobulin G inhibits angiogenesis in tumor.
Topics: Adenoviridae; Animals; Cell Line, Tumor; Cell Proliferation; Female; Genetic Therapy; Immunoglobulin Fc Fragments; Immunoglobulin G; Integrin alphaV; Integrin beta3; Mice; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Recombinant Fusion Proteins; Transduction, Genetic | 2004 |
Cloning and characterization of Adinbitor, a novel disintegrin from the snake venom of Agkistrodon halys brevicaudus stejneger.
Topics: Agkistrodon; Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; Cell Proliferation; Cell Survival; Chick Embryo; Chromatography; Cloning, Molecular; Collagen; Crotalid Venoms; Disintegrins; DNA, Complementary; Dose-Response Relationship, Drug; Drug Combinations; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 2; Genetic Vectors; Inhibitory Concentration 50; Laminin; Methylcellulose; Molecular Sequence Data; Neovascularization, Pathologic; Oligopeptides; Platelet Aggregation; Proteoglycans; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2004 |
Addition of integrin binding sequence to a mutant human endostatin improves inhibition of tumor growth.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Endostatins; Female; Half-Life; Humans; Integrins; Ligands; Mice; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Ovarian Neoplasms | 2004 |
Targeting liposomes to tumor endothelial cells for neutron capture therapy.
Topics: Boron; Boron Neutron Capture Therapy; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA, Neoplasm; Endothelium, Vascular; Gamma Rays; Humans; Isotopes; Liposomes; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2004 |
Enhancement of the antiangiogenic activity of interleukin-12 by peptide targeted delivery of the cytokine to alphavbeta3 integrin.
Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; CHO Cells; Cloning, Molecular; Cricetinae; Flow Cytometry; Integrin alphaVbeta3; Interferon-gamma; Interleukin-12; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Necrosis; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides; Plasmids; Protein Engineering; Protein Isoforms; Receptors, Interleukin; Receptors, Interleukin-12; Recombinant Fusion Proteins; Recombinant Proteins; Signal Transduction; Time Factors; Transfection | 2004 |
Targeting tumor angiogenic vasculature using polymer-RGD conjugates.
Topics: Animals; Cell Line, Tumor; Cells, Cultured; Dose-Response Relationship, Drug; Drug Delivery Systems; Humans; Male; Mice; Mice, SCID; Neovascularization, Pathologic; Oligopeptides; Polymers; Prostatic Neoplasms; Xenograft Model Antitumor Assays | 2005 |
Liposomalized oligopeptides in cancer therapy.
Topics: Animals; Antineoplastic Agents; Cell Line; Drug Carriers; Humans; Liposomes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Structure; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Oligopeptides | 2005 |
Integrin alpha v beta 3-targeted imaging of lung cancer.
Topics: Animals; Cell Adhesion; Chromatography, High Pressure Liquid; Copper; Dimerization; Dose-Response Relationship, Drug; Fluorodeoxyglucose F18; Humans; Integrin alphaVbeta3; Kinetics; Lung; Lung Neoplasms; Male; Mice; Mice, SCID; Microscopy, Fluorescence; Models, Chemical; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides; Polyethylene Glycols; Positron-Emission Tomography; Protein Binding; Protein Structure, Tertiary; Radiopharmaceuticals; Time Factors | 2005 |
Transporting silence: design of carriers for siRNA to angiogenic endothelium.
Topics: Angiogenesis Inhibitors; Animals; Cells, Cultured; Drug Delivery Systems; Flow Cytometry; Humans; Indicators and Reagents; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Neovascularization, Pathologic; Oligopeptides; Peptides; Phosphatidylethanolamines; Polyethylene Glycols; RNA, Small Interfering | 2005 |
Study of the labeling of two novel RGD-peptidic derivatives with the precursor [99mTc(H2O)3(CO)3]+ and evaluation for early angiogenesis detection in cancer.
Topics: Animals; Female; Isotope Labeling; Mice; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organotechnetium Compounds; Radionuclide Imaging; Radiopharmaceuticals; Technetium Compounds; Tissue Distribution | 2006 |
Targeting tumor angiogenesis: comparison of peptide and polymer-peptide conjugates.
Topics: Animals; Cell Line, Tumor; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Male; Metabolic Clearance Rate; Methacrylates; Mice; Mice, SCID; Neovascularization, Pathologic; Oligopeptides; Organ Specificity; Prostatic Neoplasms; Radionuclide Imaging; Tissue Distribution | 2005 |
Integrin alphavbeta3 as a target for blocking HIV-1 Tat-induced endothelial cell activation in vitro and angiogenesis in vivo.
Topics: Animals; Aorta; Benzimidazoles; Cattle; Cell Line, Transformed; Chick Embryo; Chickens; Endothelium, Vascular; Gene Products, tat; HIV Infections; HIV-1; Humans; In Vitro Techniques; Integrin alphaVbeta3; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Signal Transduction; Swine; tat Gene Products, Human Immunodeficiency Virus; Umbilical Veins | 2005 |
MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle.
Topics: Animals; Binding, Competitive; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Integrin alphaVbeta3; Lipids; Liposomes; Magnetic Resonance Imaging; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Models, Biological; Nanostructures; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Platelet Endothelial Cell Adhesion Molecule-1; Umbilical Veins | 2005 |
Biological and molecular properties of a new alpha(v)beta3/alpha(v)beta5 integrin antagonist.
Topics: Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Cattle; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Chickens; Crystallography, X-Ray; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibroblast Growth Factor 2; Glycine; Guinea Pigs; Humans; Inhibitory Concentration 50; Integrin alphaVbeta3; Integrins; Ligands; Mice; Mice, Nude; Microcirculation; Models, Chemical; Models, Molecular; Molecular Conformation; Monte Carlo Method; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Platelet Aggregation; Protein Binding; Protein Conformation; Receptors, Vitronectin; Recombinant Proteins; Stochastic Processes; Vascular Endothelial Growth Factor A; Vitronectin | 2005 |
Tumor angiogenic vasculature targeting with PAMAM dendrimer-RGD conjugates.
Topics: Angiogenesis Inhibitors; Animals; Cell Line; Dendrimers; Drug Delivery Systems; Humans; Integrins; Mice; Molecular Structure; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Polyamines | 2005 |
Molecular targeting with peptides or peptide-polymer conjugates: just a question of size?
Topics: Animals; Drug Delivery Systems; Humans; Integrin alphaVbeta3; Ligands; Neovascularization, Pathologic; Oligopeptides; Peptides; Polymers; Protein Binding; Radioimmunotherapy; Signal Transduction | 2005 |
Polymer-peptide conjugates for angiogenesis targeted tumor radiotherapy.
Topics: Animals; Drug Carriers; Humans; Male; Metabolic Clearance Rate; Methacrylates; Mice; Mice, SCID; Neovascularization, Pathologic; Oligopeptides; Organ Specificity; Prostatic Neoplasms; Radiopharmaceuticals; Radiotherapy; Technetium; Tissue Distribution; Treatment Outcome; Yttrium Radioisotopes | 2006 |
Antiangiogenic therapy decreases integrin expression in normalized tumor blood vessels.
Topics: Adenoma, Islet Cell; Animals; Axitinib; Bacteriophage M13; Endothelial Cells; Female; Imidazoles; Indazoles; Integrin alpha5beta1; Integrin alphaVbeta3; Male; Mice; Mice, Transgenic; Microscopy, Fluorescence; Neovascularization, Pathologic; Oligopeptides; Pancreatic Neoplasms; Substrate Specificity | 2006 |
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate-containing RGD peptide liposomes inhibits experimental arthritis.
Topics: Animals; Arthritis; Dexamethasone; Drug Carriers; Endothelial Cells; Female; Liposomes; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Rats | 2006 |
Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects.
Topics: Animals; Cell Line, Tumor; Coated Materials, Biocompatible; Glioblastoma; Humans; Mice; Mice, Nude; Microscopy, Fluorescence; Neovascularization, Pathologic; Oligopeptides; Particle Size; Quantum Dots; Spectrophotometry, Infrared; Whole Body Imaging | 2006 |
ICS-283: a system for targeted intravenous delivery of siRNA.
Topics: Animals; Drug Delivery Systems; Humans; Mice; Nanostructures; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Polyethyleneimine; RNA, Small Interfering; Vascular Endothelial Growth Factor Receptor-2 | 2006 |
Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification.
Topics: Amino Acid Sequence; Anoikis; Cell Adhesion; Cell Line; Endothelium, Vascular; Extracellular Matrix; Glycosylation; Humans; Hyperglycemia; Mass Spectrometry; Models, Molecular; Neovascularization, Pathologic; Neovascularization, Physiologic; Oligopeptides; Peptide Mapping | 2006 |
Blockade of alpha v beta3 and alpha v beta5 integrins by RGD mimetics induces anoikis and not integrin-mediated death in human endothelial cells.
Topics: Anoikis; Apoptosis; Benzocycloheptenes; Cell Culture Techniques; Cell Death; Endothelium, Vascular; Fetal Blood; gamma-Aminobutyric Acid; Humans; Integrin alphaVbeta3; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Umbilical Veins; Vitronectin | 2006 |
Tumor-specific expression of the RGD-alpha3(IV)NC1 domain suppresses endothelial tube formation and tumor growth in mice.
Topics: Adenoviridae; Animals; Autoantigens; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Collagen Type IV; DNA-Binding Proteins; Endothelium, Vascular; Fibrosarcoma; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Prostatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Telomerase; Transfection; Transplantation, Heterologous; Umbilical Veins | 2006 |
Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner.
Topics: Animals; Carcinoma, Squamous Cell; Cells, Cultured; Endothelial Cells; Ferric Compounds; Humans; Integrin alphaVbeta3; Magnetic Resonance Imaging; Mice; Mice, Nude; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Particle Size; Propylamines; Silanes | 2007 |
RGD targeted poly(L-glutamic acid)-cystamine-(Gd-DO3A) conjugate for detecting angiogenesis biomarker alpha(v) beta3 integrin with MRT, mapping.
Topics: Animals; Biomarkers; Cell Line; Contrast Media; Cystamine; Drug Delivery Systems; Humans; Image Enhancement; Integrin alphaVbeta3; Magnetic Resonance Imaging; Neovascularization, Pathologic; Oligopeptides; Organometallic Compounds; Polyglutamic Acid | 2007 |
Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature.
Topics: Amino Acid Motifs; Animals; Cattle; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Cisplatin; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Inhibitory Concentration 50; Integrin alphaV; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Organometallic Compounds; Peptides; Platinum | 2008 |
Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature.
Topics: Animals; Cell Line, Tumor; Chelating Agents; Copper Radioisotopes; Heterocyclic Compounds, 1-Ring; Humans; Integrin alphaVbeta3; Intercellular Signaling Peptides and Proteins; Iodine Radioisotopes; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Peptides; Positron-Emission Tomography; Quantum Dots; Radiopharmaceuticals; Spectroscopy, Near-Infrared; Tissue Distribution; Transplantation, Heterologous | 2007 |
Metabolism in rats of NC100692, an RGD-peptide for imaging of angiogenesis.
Topics: Animals; Autoradiography; Carbon Radioisotopes; Male; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Rats; Rats, Sprague-Dawley | 2008 |
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Cadherins; Cell Line, Tumor; Colonic Neoplasms; Endothelial Cells; Endothelium, Vascular; Extracellular Matrix; Extracellular Matrix Proteins; Humans; Integrins; Intercellular Junctions; Lung Neoplasms; Mice; Mice, SCID; Molecular Sequence Data; Neoplasm Invasiveness; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Transforming Growth Factor beta | 2008 |
Self-assembled glycol chitosan nanoparticles for the sustained and prolonged delivery of antiangiogenic small peptide drugs in cancer therapy.
Topics: Angiogenesis Inhibitors; Animals; Chitosan; Delayed-Action Preparations; Drug Carriers; Glycols; Male; Materials Testing; Melanoma; Mice; Mice, Nude; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Treatment Outcome | 2008 |
Preparation of a promising angiogenesis PET imaging agent: 68Ga-labeled c(RGDyK)-isothiocyanatobenzyl-1,4,7-triazacyclononane-1,4,7-triacetic acid and feasibility studies in mice.
Topics: Animals; Coordination Complexes; Feasibility Studies; Gallium Radioisotopes; Heterocyclic Compounds; Hindlimb; Humans; Hypoxia; Ischemia; Isothiocyanates; Male; Mice; Neovascularization, Pathologic; Oligopeptides; Positron-Emission Tomography; Staining and Labeling; Transplantation, Heterologous | 2008 |
Enhancement of antitumor properties of TRAIL by targeted delivery to the tumor neovasculature.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 8; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Fas-Associated Death Domain Protein; Female; Humans; Integrin alphaVbeta3; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Skin; Survival Rate; TNF-Related Apoptosis-Inducing Ligand | 2008 |
Starving tumors.
Topics: Animals; Antibodies, Monoclonal; Chick Embryo; Humans; Integrins; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Receptors, Cytoadhesin; Receptors, Vitronectin | 1995 |
Effects of fibrin on the angiogenesis in vitro of bovine endothelial cells in collagen gel.
Topics: Amino Acid Sequence; Animals; Cattle; Cells, Cultured; Collagen; Endothelium, Vascular; Fibrin; Fibroblast Growth Factor 2; Gels; Immunoglobulin G; Molecular Sequence Data; Neovascularization, Pathologic; Oligopeptides; Structure-Activity Relationship; Urokinase-Type Plasminogen Activator | 1995 |
Alpha v integrins as receptors for tumor targeting by circulating ligands.
Topics: Amino Acid Sequence; Animals; Antigens, Viral; Bacteriophages; Breast Neoplasms; Drug Carriers; Female; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Transplantation, Heterologous | 1997 |
The Tat protein of human immunodeficiency virus type-1 promotes vascular cell growth and locomotion by engaging the alpha5beta1 and alphavbeta3 integrins and by mobilizing sequestered basic fibroblast growth factor.
Topics: Binding, Competitive; Cell Adhesion; Cell Division; Cell Movement; Cytokines; Endothelium, Vascular; Extracellular Matrix Proteins; Fibroblast Growth Factor 2; Gene Products, tat; Genes, tat; Heparan Sulfate Proteoglycans; HIV-1; Humans; Macromolecular Substances; Molecular Mimicry; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Protein Conformation; Receptors, Fibronectin; Receptors, Vitronectin; Recombinant Proteins; Sarcoma, Kaposi; Skin Neoplasms; Solubility; tat Gene Products, Human Immunodeficiency Virus | 1999 |
A novel disintegrin salmosin inhibits tumor angiogenesis.
Topics: Allantois; Animals; Antineoplastic Agents; Carcinoma; Cattle; Cell Adhesion; Cells, Cultured; Chick Embryo; Chorion; Crotalid Venoms; Endothelium, Vascular; Fibroblast Growth Factor 2; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Receptors, Vitronectin; Tumor Cells, Cultured; Vitronectin | 1999 |
Neovascular targeting with cyclic RGD peptide (cRGDf-ACHA) to enhance delivery of radioimmunotherapy.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Breast Neoplasms; Combined Modality Therapy; Female; Heterocyclic Compounds; Humans; Indium Radioisotopes; Metabolic Clearance Rate; Mice; Mice, Nude; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Radioimmunotherapy; Radiopharmaceuticals; Tumor Cells, Cultured | 2000 |
Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Autoantigens; Binding Sites; Cattle; Cell Adhesion; Cell Division; Collagen; Collagen Type IV; Endothelium, Vascular; Humans; Integrin alpha6beta1; Integrins; Melanoma; Mutation; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Protein Binding; Receptors, Vitronectin; Sequence Deletion | 2000 |
Disruption of matrix metalloproteinase 2 binding to integrin alpha vbeta 3 by an organic molecule inhibits angiogenesis and tumor growth in vivo.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Division; Chick Embryo; Chorion; Collagen; Cricetinae; Endothelium, Vascular; Enzyme Activation; Histocytochemistry; Immunoblotting; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Melanoma; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Protein Binding; Receptors, Vitronectin; Tumor Cells, Cultured; Vitronectin | 2001 |
Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics.
Topics: Animals; Extracellular Matrix Proteins; Glycosylation; Humans; Integrins; Iodine Radioisotopes; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Oligopeptides; Osteosarcoma; Radionuclide Imaging; Receptors, Vitronectin | 2001 |
Highly efficient transduction of endothelial cells by targeted artificial virus-like particles.
Topics: Antineoplastic Agents; Endothelium, Vascular; Gene Targeting; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Integrins; Liposomes; Neoplasms; Neovascularization, Pathologic; Oligopeptides; Polyethyleneimine; Transduction, Genetic | 2001 |
Inhibition of angiogenesis and tumor growth by SCH221153, a dual alpha(v)beta3 and alpha(v)beta5 integrin receptor antagonist.
Topics: Allantois; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Adhesion; Cell Division; Chick Embryo; Chorion; Endothelial Growth Factors; Endothelium, Vascular; Female; Fibroblast Growth Factor 2; Growth Inhibitors; Humans; Integrins; Intercellular Signaling Peptides and Proteins; Lymphokines; Melanoma; Mice; Mice, SCID; Molecular Mimicry; Neovascularization, Pathologic; Neovascularization, Physiologic; Oligopeptides; Peptides; Receptors, Vitronectin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vitronectin; Xenograft Model Antitumor Assays | 2001 |
Intravitreal injection of plasminogen kringle 5, an endogenous angiogenic inhibitor, arrests retinal neovascularization in rats.
Topics: Angiogenesis Inhibitors; Animals; Capillaries; Cell Count; Cells, Cultured; Endothelium, Vascular; Humans; Hypoxia; Injections; Kringles; Neovascularization, Pathologic; Oligopeptides; Oxygen; Peptide Fragments; Plasminogen; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Recombinant Proteins; Reference Values; Retina; Retinal Diseases; Retinal Vessels; Vitreous Body | 2001 |
A novel synthetic Arg-Gly-Asp-containing peptide cyclo(-RGDf==V-) is the potent inhibitor of angiogenesis.
Topics: Animals; Binding Sites; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic | 2001 |
Suppression of murine collagen-induced arthritis by targeted apoptosis of synovial neovasculature.
Topics: Animals; Apoptosis; Arthritis, Experimental; Bacteriophage M13; Binding, Competitive; Collagen; Drug Delivery Systems; Genetic Therapy; In Situ Nick-End Labeling; Integrins; Male; Mice; Mice, Inbred DBA; Neovascularization, Pathologic; Oligopeptides; Peptide Fragments; Receptors, Vitronectin; Synovial Membrane | 2001 |
Inhibition of the alpha-nu integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Cricetinae; Endothelium; Infusions, Parenteral; Integrin alpha1; Leukocytes; Male; Melanoma; Microcirculation; Neoplasm Metastasis; Neoplasms, Experimental; Neovascularization, Pathologic; Oligopeptides; Skin Neoplasms | 2002 |
Kinetics of integrin expression in the mouse model of proliferative retinopathy and success of secondary intervention with cyclic RGD peptides.
Topics: Animals; Diabetic Retinopathy; Disease Models, Animal; Integrins; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Oligopeptides; Peptides, Cyclic; Platelet Aggregation Inhibitors; Retinal Vessels | 2002 |
Targeting of liposomes to angiogenic endothelial cells.
Topics: Animals; Drug Carriers; Drug Delivery Systems; Endothelium, Vascular; Liposomes; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; Receptors, Vitronectin | 2002 |