arginine has been researched along with Pulmonary Hypertension in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 54 (27.69) | 18.2507 |
| 2000's | 68 (34.87) | 29.6817 |
| 2010's | 64 (32.82) | 24.3611 |
| 2020's | 9 (4.62) | 2.80 |
| Authors | Studies |
|---|---|
| Ding, JJ; Gu, M; Lu, Q; Zhang, WT | 1 |
| Aschner, JL; Avachat, C; Birnbaum, AK; Fike, CD; Sherwin, CM | 1 |
| Liu, X; Wang, D; Wei, Q; Yu, Y; Zhang, L; Zhou, L; Zou, L | 1 |
| Elwing, JM; Fallon, MB; Jose, A; Kawut, SM; McCormack, FX; Nichols, WC; Pauciulo, MW; Sherman, KE | 1 |
| Aschner, JL; Cunningham, G; Dikalova, A; Fike, CD; Kaplowitz, MR; Summar, M | 2 |
| Jankowski, Z; Kocić, I; Sztormowska-Achranowicz, K | 1 |
| Contiero, B; Domenech, O; Guglielmini, C; Poser, H; Valente, C; Zini, E | 1 |
| Beghetti, M; Milano, G; Reinero, M; Samaja, M; Segesser, LKV; Tozzi, P | 1 |
| Değertekin, MM; Gezer Taş, S; Güleç, S; İşbir, T; Mutlu, B; Olgun Yıldızeli, Ş; Özveren, O; Şimşek, MA; Türer Cabbar, A; Yanartaş, M; Yıldızeli, B | 1 |
| Akin, İ; Behnes, M; Sahin, A; Yildiz, M | 1 |
| Feng, T; Ge, RL; Quanyu, Y; Yuhong, L; Zhengzhong, B | 1 |
| Morris, CR; Shilo, NR | 1 |
| Ahmadipour, B; Khajali, F; Sharifi, M | 1 |
| El Amrousy, D; El-Serogy, H; Farag, M; Zoair, A | 1 |
| Abd El-Hameed, F; Badraia, I; Donia, A; El-Shanshory, M; Mabrouk, M | 1 |
| Bakr, A; Brandes, RP; Cooke, JP; Ghofrani, HA; Gierhardt, M; Grimminger, F; Hamada, F; Hemeida, R; Huang, N; Janssen, W; Pak, O; Schermuly, RT; Seeger, W; Sommer, N; Taye, A; Weissmann, N; Witzenrath, M | 1 |
| Fukuda, K; Ono, T; Sasayama, S; Satoh, T; Tamura, Y | 1 |
| Chen, R; Chen, XY; Fan, XF; Gong, YS; Hu, LG; Liu, SF; Mao, SZ; Xue, F; Yuan, GS | 1 |
| Kimura, J; Misaka, S; Munakata, M; Ogata, H; Sato, S; Shikama, Y; Yatabe, M | 1 |
| Al-Hiti, H; Baňasová, A; Chovanec, M; Herget, J; Kautzner, J; Melenovský, V; Vajnerová, O | 1 |
| Bergmeister, H; Bonderman, D; Jakowitsch, J; Lang, IM; Mascherbauer, J; Panzenböck, A; Schreiber, C; Strobl, M; Wexberg, P; Winter, MP | 1 |
| Hassanpour, H; Khajali, F; Moghaddam, MH | 1 |
| Courtney, D; Hwang, S; Kline, JA; Lee, YY; Watts, J | 1 |
| Haghighat, M; Khajali, F; Saki, A | 1 |
| Deeks, SG; Ganz, P; Hsue, PY; Hur, S; Leone, A; Macgregor, JS; Martin, JN; Mistry, V; Nitta, EM; Parikh, RV; Scherzer, R | 1 |
| Amr, D; Ibrahim, B; Mohamed, el-S; Mokhtar, M; Noha, el-K | 1 |
| Bálint, Z; Crnkovic, S; Egemnazarov, B; Gattinger, N; Ghanim, B; Jain, P; Klepetko, W; Kovacs, G; Kwapiszewska, G; Marsh, LM; Olschewski, A; Schermuly, RT; Seay, U; Weissmann, N | 1 |
| Agha, AM; Ahmed, LA; Obaid, AA; Zaki, HF | 1 |
| Dubois, O; Duluc, L; Iannone, L; Leiper, J; Rhodes, CJ; Wharton, J; Wilkins, MR; Wojciak-Stothard, B; Zhao, L | 1 |
| Benninger, RK; Bowler, RP; Enghild, JJ; Gally, F; Goldstrohm, DA; Hartney, JM; Johnson, R; Kosmider, B; Leahy, KF; Nozik-Grayck, E; Oberley-Deegan, RE; Scavenius, C; Stidham, T; Valnickova-Hansen, Z; Weaver, MR; Zimmermann, AK | 1 |
| Backes, CH; Chen, B; Klebanoff, MA; Nelin, LD; Peterson, E; Rogers, LK; Trittmann, JK | 1 |
| Aschner, JL; Fike, CD | 1 |
| Coates, TD; Detterich, J; Harmatz, P; Meloni, A; Pepe, A; Wood, JC | 1 |
| Belik, J; Dhaliwal, R; Grasemann, H; Ivanovska, J; Jankov, RP; Kantores, C; McNamara, PJ; Scott, JA | 1 |
| Fang, ZF; Hu, XQ; Huang, YY; Shen, XQ; Tang, JJ; Tang, L; Zhou, SH | 1 |
| Hassell, K; Kim, HY; Klings, ES; Kuypers, FA; Kwiatkowski, JL; Larkin, S; Morris, CR; Neufeld, EJ; Olivieri, NF; Porter, JB; Suh, JH; Sweeters, N; Taher, A; Thompson, AA; Trachtenberg, F; Vichinsky, EP; Virzi, L; Wood, J | 1 |
| Bondesson, U; Egeröd, H; Hedeland, M; Henrohn, D; Sandqvist, A; Wernroth, L; Wikström, G | 1 |
| Hassanpour, H; Khajali, F; Pirany, N; Pour-Reza, J; Sharifi, MR | 1 |
| Ambrozova, G; Cerna, A; Kadlec, J; Klinke, A; Kolarova, H; Koudelka, A; Kubala, L; Kuchta, R; Kuchtova, Z; Lojek, A; Pekarova, M; Sindlerova Svihalkova, L; Trundova, M | 1 |
| Chu, L; de Perrot, M; Granton, E; Granton, J; Hsin, M; Keshavjee, S; Lin, K; Peng, J; Waddell, T; Wu, L; Yin, L; Yu, A; Zhao, YD | 1 |
| Beloiartsev, A; Clish, CB; Dhakal, BP; Domos, C; Farrell, L; Gerszten, RE; Hemnes, AR; Lewis, GD; Ngo, D; Pappagianopoulos, PP; Pugh, ME; Shi, X; Sinha, S; Souza, A | 1 |
| Calvo, E; García-Álvarez, A; Vázquez, J | 1 |
| Arriaza, K; Böger, RH; Brito, J; Klose, H; Leon-Velarde, F; Lüneburg, N; Pena, E; Siques, P | 1 |
| Lin, HC; Ma, L; Neu, J; Zhou, P | 1 |
| Chen, B; Chicoine, LG; Jin, Y; Liu, Y; Nelin, LD; Trittmann, JK | 1 |
| Chen, P; Fang, Z; Hu, X; Huang, Y; Shen, X; Zhou, S | 1 |
| Beyer, J; Ewert, R; Halank, M; Hoeffken, G; Kolditz, M; Opitz, C; Rubens, C; Schellong, S | 1 |
| Ali, O; Bauersachs, J; Bédard, E; Diller, GP; Gatzoulis, MA; Gibbs, JS; Hobbs, AJ; Howard, LS; Okonko, DO; Thum, T; van Eijl, S; Wharton, J; Wilkins, MR; Wort, SJ | 1 |
| Cau, SB; Dias-Junior, CA; Tanus-Santos, JE | 1 |
| Biemond, BJ; Brandjes, DP; Duits, AJ; Kappers-Klunne, MC; Landburg, PP; Mac Gillavry, MR; Muskiet, FA; Schnog, JJ; Teerlink, T; van Beers, EJ; van Esser, JW | 1 |
| Dimitroula, H; Dimitroulas, T; Giannakoulas, G; Karvounis, H; Koliakos, G; Settas, L; Sfetsios, T | 1 |
| Gladwin, MT; Kato, GJ; Morris, CR | 1 |
| Morris, CR | 2 |
| Bahr, MJ; Bode-Böger, SM; Gebel, M; Haller, H; Hesse, G; Kielstein, JT; Manns, MP; Martens-Lobenhoffer, J; Panning, B; Terkamp, C; Tsikas, D | 1 |
| Blackwelder, WC; Hazen, SL; Kato, GJ; Machado, RF; Taylor, JG; Wang, Z | 1 |
| Costello, CM; Dooley, I; Howell, K; McLoughlin, P; Sands, M | 1 |
| Fan, XF; Gong, YS; Guo, YM; Hong, L; Hu, LG; Mao, SZ; Zhang, L | 1 |
| Biemond, BJ; Brandjes, DP; Duits, AJ; Landburg, PP; Muskiet, FA; Schnog, JB; Teerlink, T | 1 |
| Huang, DD; Luo, D; Luo, W; Ou, JS; Ou, ZJ; Wang, ZP; Wei, W; Zhang, X | 1 |
| Barr, FE; Macrae, D | 1 |
| Dimitroula, H; Dimitroulas, T; Garyfallos, A; Giannakoulas, G; Karvounis, H; Koliakos, G; Papadopoulou, K; Parcharidou, D; Settas, L; Sfetsios, T; Styliadis, I | 1 |
| Ozturk, EI; Uma, S | 1 |
| Aschner, JL; Eaton, F; Magarik, J; Rey-Parra, GJ; Summar, M; Thébaud, B; Vadivel, A; Zeng, H | 1 |
| Adams, MR; Celermajer, DS; Ilsar, R; Kritharides, L; Levitt, J; Ng, MK | 1 |
| Augustine, M; Chicoine, LG; Cua, CL; Jin, Y; Nash, PL; Nelin, LD; Rogers, LK | 1 |
| Gielis, JF; Lin, JY; Moens, AL; Schmidt, HH; Van Schil, PE; Wingler, K | 1 |
| George, P; Gladwin, MT; Zuckerbraun, BS | 1 |
| Fleming, I; Ghofrani, HA; Grimminger, F; Leiper, J; Mayer, K; Pullamsetti, SS; Savai, R; Schaefer, MB; Schermuly, RT; Schudt, C; Seeger, W; Weissmann, N; Wilhelm, J | 1 |
| Talukder, MA; Zweier, JL | 1 |
| Edo, K; Ishibashi, T; Ishikawa, K; Maruyama, Y; Ogata, H; Takahashi, T; Watanabe, M | 1 |
| Dai, G; Ma, P; Pei, Y; Wang, X; Xu, Q; Yan, L; Zhang, W; Zhang, X; Zheng, P | 1 |
| Artuković, B; Cenan, S; Cooper, RG; Dinarina-Sablić, M; Dzaja, P; Grabarević, Z; Tisljar, M; Zelenika, TA | 1 |
| Das, SK; Fulkerson, MB; Gellar, MA; Kline, JA; Watts, JA | 1 |
| Borowski, AG; Hazen, SL; Moravec, CS; Shao, Z; Shrestha, K; Sweet, W; Tang, WH; Thakur, A; Thomas, JD; Wang, Z | 1 |
| Cevik, A; Gulbahar, O; Kula, S; Oguz, D; Olgunturk, R; Pasaoglu, H; Sanli, C; Tunaoglu, FS | 1 |
| Aramburo, A; Black, SM; Fineman, JR; Kalkan, G; Kallarackal, S; Kumar, S; Rafikov, R; Rehmani, I; Sharma, S; Sun, X; Tian, J | 1 |
| Billecke, SS; D'Alecy, LG; Marcovitz, PA | 1 |
| Atli, O; Demirel-Yilmaz, E; Ilgin, S; Sirmagul, B; Usanmaz, SE | 1 |
| Borowski, AG; Schuster, A; Tang, WH; Thakur, A; Thomas, JD; Wang, Z | 1 |
| Calvert, TJ; Chen, B; Chicoine, LG; Jin, Y; Liu, Y; Nelin, LD | 1 |
| Aggarwal, S; Black, SM; Burns, T; Dasarathy, S; Fineman, JR; Fratz, S; Kumar, S; Lu, Q; Radman, M; Rafikov, R; Rafikova, O; Schreiber, C; Sharma, S; Sun, X; Wright, J | 1 |
| Dong, WQ; Zhang, MX | 1 |
| Haraguchi, R; Kitazawa, R; Kitazawa, S; Kurata, M; Makita, K; Munenori, K; Soga, Y; Takeji, M; Yoshida, K | 1 |
| Du, J; Li, J; Qi, J; Tang, C; Wei, B | 1 |
| Bing, W; Chaoshu, T; Jian, L; Jianguang, Q; Junbao, D | 1 |
| Arrigoni, FI; Haworth, SG; Leiper, JM; Vallance, P | 1 |
| Claster, S; Hagar, W; Kepka-Lenhart, D; Kuypers, FA; Machado, L; Morris, CR; Morris, SM; Van Warmerdam, J; Vichinsky, EP | 1 |
| Peacock, AJ | 1 |
| Ni, W; Xu, YJ; Zhang, YC; Zhang, ZX; Zhen, GH | 1 |
| Amtorp, O; Boberg, B; Ravn, JB; Sander, M; Welling, KL | 1 |
| Gladwin, MT; Jison, ML | 1 |
| Carey, RM; Johns, RA; Leiper, JM; Li, D; Millatt, LJ; Siragy, HM; Whitley, GS | 1 |
| Cooke, JP | 1 |
| Archer, SL; McMurtry, MS; Michelakis, ED; Sonnenberg, B | 1 |
| Asano, M; Manabe, T; Maruyama, K; Mishima, A; Nomura, N; Sasaki, S; Ukai, T | 1 |
| Aschner, JL | 1 |
| Allamand, F; Fernández, MS; Germain, AM; Lacassie, HJ; López, H; Valdés, G | 1 |
| Becker, EJ; Hester, RK; Jeffrey, JS; Martinez-Lemus, LA; Meininger, GA; Odom, TW; Ramirez, GA | 1 |
| Kost, CK; Likness, MM; Schlenker, EH | 1 |
| Ao, Q; Huang, L; Wang, D; Xiong, M; Zhu, P | 1 |
| Archer, SL; Badesch, DB; Barst, RJ; Fanburg, BL; Gail, DB; Garcia, JG; Kao, PN; Knowles, JA; Loyd, JE; McGoon, MD; Morse, JH; Newman, JH; Nichols, WC; Rabinovitch, M; Rodman, DM; Stevens, T; Tuder, RM; Voelkel, NF | 1 |
| Amano, H; Fuse, D; Harasawa, H; Matsuda, T; Nakamoto, T | 1 |
| Krywawych, S; Petros, AJ; Pierce, CM | 2 |
| Damiano, RJ; Deshpande, SP; Lawton, JS; Zanaboni, PB | 1 |
| Gerlach, RF; Metzger, IF; Rocha, JB; Souza-Costa, DC; Tanus-Santos, JE; Zerbini, T | 1 |
| Dreyhaupt, J; Eitel, K; Fiehn, W; Gorenflo, M; Gross, J; Hagl, S; Ullmann, MV | 1 |
| Aigner, C; Fink, L; Ghofrani, HA; Grimminger, F; Haredza, P; Kiss, L; Klepetko, W; Muyal, JP; Pullamsetti, S; Schermuly, RT; Seeger, W; Voswinckel, R; Weissmann, N | 1 |
| Bing, W; Chaoshu, T; Hui, Y; Jian, L; Jianguang, Q; Junbao, D | 1 |
| Bode-Böger, SM; Fliser, D; Hesse, G; Hoeper, MM; Kielstein, JT; Martens-Lobenhoffer, J; Takacs, A | 1 |
| Blackwelder, WC; Gladwin, MT; Hazen, SL; Kato, GJ; Morris, CR; Morris, SM; Poljakovic, M; Sachdev, V; Vichinsky, EP; Wang, X | 1 |
| Erzurum, SC; Lara, AR | 1 |
| Li, JC; Liu, YJ; Pan, JQ; Sun, WD; Tan, X; Wang, XL | 1 |
| Chu, SJ; Lee, TY; Li, MH; Lin, SH; Yan, HC | 1 |
| Anthony, S; Hubank, M; Leiper, JM; Smith, CL; Vallance, P | 1 |
| Dias-Junior, CA; Evora, PR; Moreno, H; Souza-Silva, AR; Tanus-Santos, JE; Uzuelli, JA | 1 |
| Waugh, WH | 1 |
| Cooke, JP; Kielstein, JT | 1 |
| Howard, LS; Morrell, NW | 1 |
| Kato, GJ; Kuypers, FA; Larkin, S; Lavrisha, L; Morris, CR; Singer, T; Vichinsky, EP | 1 |
| Czp, A | 1 |
| Tanus-Santos, JE | 1 |
| Dandel, M; Hetzer, R; Lehmkuhl, HB | 1 |
| Hu, YX; Li, JC; Pan, JQ; Sun, WD; Tan, X; Wang, JY; Wang, XL | 1 |
| Chaoshu, T; Junbao, D; Lin, S; Yanfei, W | 1 |
| Barr, FE; Canter, JA; Christian, KG; Christman, BW; Drinkwater, DC; Rice, GD; Scholl, FG; Smith, HA; Summar, ML | 1 |
| Morris, CR; Singer, ST; Walters, MC | 1 |
| Azuma, H; Doi, S; Mizutani, S; Sasaki, A | 1 |
| Bonderman, D; Hitsch, R; Jakowitsch, J; Klepetko, W; Kneussl, MP; Lang, IM; Mittermayer, F; Panzenboeck, A; Sadushi, R; Skoro-Sajer, N; Wolzt, M | 1 |
| Abrahams, S; Louw, VJ; Smedema, JP | 1 |
| Dauzat, M; Goret, L; Guiraud, I; Obert, P; Tanguy, S | 1 |
| Arnold, R; Eichhorn, J; Gorenflo, M; Gross, J; Hoss, K; Kark, M; Klimpel, H; Loukanov, T; Sebening, C; Ulmer, HE | 1 |
| Maarsingh, H; Meurs, H; Pera, T | 1 |
| Archer, SL; Hampl, V; Nelson, DP; Weir, EK | 1 |
| Barer, G; Howard, P; Kapeller, K; Russell, P; Wright, C | 1 |
| Berger, JI; Gibson, RL; Mayock, DE; Redding, GJ; Standaert, TA; Truog, WE | 1 |
| Alvarez, TA; Choy, JS; Hacker, AD; Keller, PA; Madden, JA | 1 |
| Camporesi, EM; Hakim, TS; Oleary, CE; Picone, A | 1 |
| Langleben, D; Levy, RD; Mehta, S; Stewart, DJ | 1 |
| Hughes, IE; O'Donnell, SR; Wanstall, JC | 1 |
| Chen, SC; Li, MR; Ma, G | 1 |
| Kavanagh, BP; Lindeborg, DM; Pearl, RG; Van Meurs, K | 1 |
| Bottje, WG; Ismail, M; Kirby, YK; Moore, RW; Vardeman, RC; Wideman, RF | 1 |
| Fineman, JR; Soifer, SJ; Vanderford, PA; Winters, J; Wong, J | 1 |
| Cao, W; Zeng, Z; Zhu, Y | 1 |
| Fineman, JR; Soifer, SJ; Vanderford, PA; Wong, J | 1 |
| Cao, WB; Luo, WC; Zhu, YJ | 1 |
| Maruyama, J; Maruyama, K; Miyasaka, K; Muneyuki, M; Yokochi, A | 1 |
| Bieroń, K; Dubiel, JS; Gryglewski, RJ; Kostka-Trabka, E; Surdacki, A; Zmudka, K | 1 |
| Cioffi, WG; Johnson, AA; Jordan, BS; Offner, PJ; Ogura, H; Pruitt, BA; Saitoh, D | 1 |
| Pearl, RG; Xu, H | 1 |
| Abman, SH; Ivy, DD; Kinsella, JP | 1 |
| Chang, R; Fineman, JR; Soifer, SJ; Vanderford, PA; Wong, J | 1 |
| Braner, DA; Chang, R; Fineman, JR; Soifer, SJ | 1 |
| Bath, P; Baudouin, SV; Du Bois, R; Evans, TW; Martin, JF | 1 |
| Lundberg, JM; Rudehill, A; Weitzberg, E | 1 |
| Fineman, JR; Soifer, SJ; Wong, J | 1 |
| Cocks, TM; Kemp, BK; Ritchie, BC; Smolich, JJ | 1 |
| Gewitz, MH; Mathew, R; Tun, H; Zeballos, GA | 1 |
| Lipsitz, EC; Smerling, AJ; Stolar, CJ; Weinstein, S | 1 |
| Baird, M; MacLean, MR; McCulloch, KM | 1 |
| DiBernardo, LR; Gaynor, JW; Jacobs, MT; Kirshbom, PM; Schwinn, DA; Tsui, SS; Ungerleider, RM | 1 |
| Chang, R; Fineman, JR; Johengen, M; Liddicoat, JR; Reddy, VM; Wong, J | 1 |
| Bode-Böger, SM; Böger, RH; Frölich, JC; Heinzel, D; Höper, MM; Mügge, A | 1 |
| Benditte, H; Grünberger, T; Längle, F; Mittlböck, M; Mühlbacher, F; Roth, E; Schindl, M; Soliman, T; Steininger, R; Waldmann, E; Windberger, U | 1 |
| Chen, W; Cheng, D; Yang, X | 1 |
| Maruyama, K; Mitani, Y; Sakurai, M | 1 |
| Alper, SL; Huang, YC; Nozik-Grayck, E; Piantadosi, CA; van Adelsberg, J | 1 |
| Nonami, Y | 1 |
| Cao, W; Luo, W; Wang, Z; Zeng, Z; Zhu, Y | 1 |
| Maruyama, J; Maruyama, K; Yokochi, A | 1 |
| Fagan, JM; Hayes-Licitra, SA; Rex, SE; Waxman, L | 1 |
| McMurtry, IF; Rodman, DM; Sato, K | 1 |
| Becker, EJ; Hester, RK; Jeffrey, JS; Martinez-Lemus, LA; Odom, TW | 1 |
| Arnal, JF; Darblade, B; Dinh-Xuan, AT; Pueyo, M; Rami, J | 1 |
| Bush, A; Collins, P; Kelleher, A; Li, J; Morgan, C; Penny, DJ; Redington, AN; Rigby, ML; Schulze-Neick, I; Shinebourne, EA | 1 |
| Cai, Y; Gong, Y; Lin, H; Song, W; Zhou, X | 1 |
| Ayuso, D; Delgado, MA; Esteban, A; Fernández-Segoviano, P; Hervás, M; Lorente, JA; Mon, E; Pascual, T; Rieppi, G; Soler, A; Tejedor, C | 1 |
| Baribeau, J; Berkenbosch, JW; Perreault, T | 1 |
| Wang, R; Wang, Z | 1 |
| Li, HZ; Qi, HW; Yang, JP | 1 |
| Li, G; Liang, Y; Lu, J | 1 |
| Kyotani, S; Miyatake, K; Nagaya, N; Nakanishi, N; Oya, H; Sakamaki, F; Sato, N; Uematsu, M; Ueno, K; Yamagishi, M | 1 |
| Fiehn, W; Gorenflo, M; Ulmer, HE; Werle, E; Zheng, C | 1 |
| Chen, S; Xu, Y; Zhong, N | 1 |
| Chen, L; Fan, S; Shen, W; Wang, Y; Zhang, L | 1 |
| Bettendorf, M; Fiehn, W; Gorenflo, M; Pöge, A; Ulmer, HE; Werle, E; Zheng, C | 1 |
| Galiè, N; Hoeper, MM; Rubin, LJ; Simonneau, G | 1 |
| Chang, R; Fineman, JR; Soifer, SJ | 2 |
| Adnot, S; Braquet, P; Chabrier, PE; Eddahibi, S; Raffestin, B | 1 |
| Barer, G; Bee, D; Emery, C; Oddoy, A | 1 |
| Fineman, JR; Heymann, MA; Soifer, SJ | 1 |
22 review(s) available for arginine and Pulmonary Hypertension
| Article | Year |
|---|---|
An Expanding Role of Biomarkers in Pulmonary Arterial Hypertension.
Topics: Arginine; Biomarkers; Endothelins; Humans; Hypertension, Pulmonary; Prognosis; Sensitivity and Specificity; Severity of Illness Index; von Willebrand Factor | 2017 |
Pathways to pulmonary hypertension in sickle cell disease: the search for prevention and early intervention.
Topics: Anemia, Sickle Cell; Arginine; Biomarkers; Blood Coagulation; Echocardiography; Genetic Predisposition to Disease; Hemolysis; Humans; Hypertension, Pulmonary; Hypoxia; Nitric Oxide; Oxidative Stress; Respiratory Function Tests; Risk Assessment | 2017 |
Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia.
Topics: Acetylcysteine; Antioxidants; Arginine; Bronchopulmonary Dysplasia; Citrulline; Cysteine; Fatty Acids, Unsaturated; Glutamine; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Infant, Premature; Inositol; Selenium; Vitamin A; Vitamin B Complex | 2017 |
[Role of nitric oxide in the control of the pulmonary circulation: physiological, pathophysiological, and therapeutic implications].
Topics: Animals; Arginine; Clinical Trials as Topic; Cyclic GMP; Humans; Hypertension, Pulmonary; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pulmonary Circulation | 2008 |
Nitric oxide and arginine dysregulation: a novel pathway to pulmonary hypertension in hemolytic disorders.
Topics: Arginase; Arginine; Free Radical Scavengers; Hematologic Diseases; Humans; Hypertension, Pulmonary; Nitric Oxide | 2008 |
Asthma management: reinventing the wheel in sickle cell disease.
Topics: Acute Disease; Adult; Anemia, Sickle Cell; Anti-Asthmatic Agents; Arginase; Arginine; Asthma; Black or African American; Chest Pain; Child; Child, Preschool; Combined Modality Therapy; Comorbidity; Erythrocytes, Abnormal; Genetic Predisposition to Disease; Humans; Hypertension, Pulmonary; Hypoxia; Long QT Syndrome; Nitric Oxide; Oxidative Stress; Oxygen Inhalation Therapy; Prevalence; United States | 2009 |
Inhaled nitric oxide and related therapies.
Topics: Administration, Inhalation; Administration, Oral; Arginine; Cardiac Surgical Procedures; Child; Child, Preschool; Citrulline; Clinical Trials as Topic; Endothelium-Dependent Relaxing Factors; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Injections, Intravenous; Nitric Oxide; Postoperative Complications | 2010 |
Pathogenetic role of eNOS uncoupling in cardiopulmonary disorders.
Topics: Arginine; Atherosclerosis; Biopterins; Blood Pressure; Cardiac Surgical Procedures; Cell Adhesion; Endothelium, Vascular; Folic Acid; Humans; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oxidation-Reduction; Oxygen; Reactive Oxygen Species; Vasodilation; Ventricular Remodeling | 2011 |
Nitrite in pulmonary arterial hypertension: therapeutic avenues in the setting of dysregulated arginine/nitric oxide synthase signalling.
Topics: Arginine; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Signal Transduction | 2011 |
[Endogenous metabolites--arginine/nitric oxide regulate the body's physiological function].
Topics: Animals; Arginine; Homeostasis; Humans; Hypertension; Hypertension, Pulmonary; Nitric Oxide; Vasodilation | 2012 |
Hemolytic anemia-associated pulmonary hypertension of sickle cell disease and the nitric oxide/arginine pathway.
Topics: Anemia, Hemolytic; Anemia, Sickle Cell; Arginine; Biological Availability; Humans; Hypertension, Pulmonary; Nitric Oxide; Prognosis; Pulmonary Wedge Pressure; Syndrome; Vasodilator Agents | 2003 |
A novel mechanism for pulmonary arterial hypertension?
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Humans; Hypertension, Pulmonary; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Vasomotor System | 2003 |
The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
Topics: Administration, Inhalation; Administration, Oral; Animals; Arginine; Dichloroacetic Acid; Disease Models, Animal; Humans; Hypertension, Pulmonary; Models, Biological; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Potassium Channels; Pulmonary Circulation; Purines; Rats; Sildenafil Citrate; Sulfones | 2003 |
[Nitric oxide and pulmonary hypertension].
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Inhalation; Animals; Arginine; Cyclic Nucleotide Phosphodiesterases, Type 5; Genetic Therapy; Humans; Hypertension, Pulmonary; Hypoxia; Microcirculation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pulmonary Circulation; Vasoconstriction | 2004 |
New therapeutic agents for pulmonary vascular disease.
Topics: Adult; Antihypertensive Agents; Arginine; Bosentan; Child; Drug Therapy, Combination; Epoprostenol; Humans; Hypertension, Pulmonary; Iloprost; Nitric Oxide; Phosphodiesterase Inhibitors; Platelet Aggregation Inhibitors; Sulfonamides | 2005 |
Advances in the medical treatment of pulmonary hypertension.
Topics: Antihypertensive Agents; Arginine; Endothelin Receptor Antagonists; Epoprostenol; Humans; Hypertension, Pulmonary; Nitric Oxide; Phosphodiesterase Inhibitors; Terminology as Topic | 2005 |
Clinical hemoglobinopathies: iron, lungs and new blood.
Topics: Anemia, Sickle Cell; Arginine; beta-Thalassemia; Child; Hematopoietic Stem Cell Transplantation; Humans; Hypertension, Pulmonary; Iron Chelating Agents; Iron Overload; Prognosis | 2006 |
Arginase and pulmonary diseases.
Topics: Animals; Arginase; Arginine; Asthma; Cystic Fibrosis; Disease Models, Animal; Humans; Hypertension, Pulmonary; Lung; Lung Diseases; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Urea | 2008 |
The role of nitric oxide in cardiac surgery.
Topics: Animals; Arginine; Cardiac Surgical Procedures; Disease Models, Animal; Heart Diseases; Humans; Hypertension, Pulmonary; Hypoxia; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophil Activation; Nitric Oxide; Nitric Oxide Synthase; Vasodilation | 1997 |
[Management of pulmonary circulation: mechanism of action of vasoactive substances].
Topics: Administration, Inhalation; Animals; Arginine; Hypertension, Pulmonary; Muscle, Smooth, Vascular; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Vascular Resistance | 1997 |
Endothelium-derived nitric oxide and vascular physiology and pathology.
Topics: Animals; Arginine; Arteriosclerosis; Blood Vessels; Caveolin 1; Caveolins; Cell Adhesion; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Humans; Hypertension; Hypertension, Pulmonary; Isoenzymes; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Oxidative Stress; Rabbits; Signal Transduction; Vascular Diseases; Vasodilation | 1999 |
New treatments for pulmonary arterial hypertension.
Topics: Arginine; Endothelin Receptor Antagonists; Humans; Hypertension, Pulmonary; Nitric Oxide; Phosphodiesterase Inhibitors; Prostaglandins; Vasodilator Agents | 2002 |
9 trial(s) available for arginine and Pulmonary Hypertension
| Article | Year |
|---|---|
Pulmonary hypertensive response of broiler chickens to arginine and guanidinoacetic acid under high-altitude hypoxia.
Topics: Altitude; Animals; Arginine; Chickens; Dietary Supplements; Glycine; Hypertension, Pulmonary; Hypoxia; Male; Poultry Diseases | 2018 |
Evaluation of a new formulation of epoprostenol sodium in Japanese patients with pulmonary arterial hypertension (EPITOME4).
Topics: Administration, Intravenous; Adult; Aged; Antihypertensive Agents; Arginine; Chemistry, Pharmaceutical; Drug Stability; Drug Storage; Epoprostenol; Excipients; Familial Primary Pulmonary Hypertension; Female; Humans; Hypertension, Pulmonary; Japan; Male; Middle Aged; Patient Satisfaction; Sucrose; Treatment Outcome | 2013 |
Changes in plasma levels of asymmetric dimethylarginine, symmetric dimethylarginine, and arginine after a single dose of vardenafil in patients with pulmonary hypertension.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Arginine; Atrial Function, Right; Atrial Pressure; Biomarkers; Cardiac Output; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Phosphodiesterase 5 Inhibitors; Time Factors; Treatment Outcome; Vardenafil Dihydrochloride; Vasodilator Agents | 2015 |
Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?
Topics: Administration, Oral; Adolescent; Adult; Amino Acids; Anemia, Sickle Cell; Arginase; Arginine; Biological Availability; Case-Control Studies; Echocardiography; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nitric Oxide; Ornithine; Oximetry; Pulmonary Wedge Pressure; Treatment Outcome | 2003 |
Asymmetric dimethyl arginine and symmetric dimethyl arginine levels in infants with persistent pulmonary hypertension of the newborn.
Topics: Arginine; Chromatography, High Pressure Liquid; Cohort Studies; Female; Humans; Hypertension, Pulmonary; Infant, Newborn; Intensive Care Units, Pediatric; Male; Nitric Oxide Synthase | 2004 |
Nitric oxide precursors and congenital heart surgery: a randomized controlled trial of oral citrulline.
Topics: Administration, Oral; Arginine; Blood Pressure; Cardiac Surgical Procedures; Child, Preschool; Citrulline; Double-Blind Method; Female; Fontan Procedure; Humans; Hypertension, Pulmonary; Infant; Male; Multivariate Analysis; Pilot Projects; Postoperative Complications | 2006 |
Lack of beneficial effects of L-arginine infusion in primary pulmonary hypertension.
Topics: Adolescent; Adult; Arginine; Cardiac Catheterization; Cardiac Output; Cyclic GMP; Female; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Oxygen; Pulmonary Wedge Pressure; Vascular Resistance | 1994 |
Differential systemic and pulmonary hemodynamic effects of L-arginine in patients with coronary artery disease or primary pulmonary hypertension.
Topics: Adult; Arginine; Blood Pressure; Coronary Disease; Cyclic GMP; Female; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Signal Transduction; Vascular Resistance | 1996 |
Short-term oral administration of L-arginine improves hemodynamics and exercise capacity in patients with precapillary pulmonary hypertension.
Topics: Administration, Oral; Analysis of Variance; Arginine; Double-Blind Method; Drug Administration Schedule; Exercise Tolerance; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Probability; Reference Values; Treatment Outcome | 2001 |
164 other study(ies) available for arginine and Pulmonary Hypertension
| Article | Year |
|---|---|
Association of asymmetric dimethylarginine with the pathological process of persistent pulmonary hypertension of the newborn.
Topics: Arginine; Biomarkers; Humans; Hypertension, Pulmonary; Infant, Newborn; Prospective Studies | 2022 |
Pharmacokinetics of L-Citrulline in Neonates at Risk of Developing Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension.
Topics: Arginine; Bronchopulmonary Dysplasia; Child; Citrulline; Gestational Age; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn | 2023 |
Arginine attenuates chronic mountain sickness in rats via microRNA-144-5p.
Topics: Altitude Sickness; Animals; Arginine; Hypertension, Pulmonary; Hypoxia; MicroRNAs; Rats | 2023 |
Human liver single nuclear RNA sequencing implicates BMPR2, GDF15, arginine, and estrogen in portopulmonary hypertension.
Topics: Arginine; Bone Morphogenetic Protein Receptors, Type II; Estrogens; Growth Differentiation Factor 15; Humans; Hypertension, Portal; Hypertension, Pulmonary; Liver Transplantation; Pulmonary Arterial Hypertension | 2023 |
Combined l-citrulline and tetrahydrobiopterin therapy improves NO signaling and ameliorates chronic hypoxia-induced pulmonary hypertension in newborn pigs.
Topics: Animals; Animals, Newborn; Arginine; Biopterins; Citrulline; Hypertension, Pulmonary; Hypoxia; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Signal Transduction; Swine; Vascular Resistance | 2020 |
Protective effect of nicotinamide and L-arginine against monocrotaline-induced pulmonary hypertension in rats: gender dependence.
Topics: Animals; Arginine; Female; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocardium; Niacinamide; Protective Agents; Pulmonary Artery; Rats; Rats, Wistar | 2020 |
Symmetric dimethylarginine in dogs with myxomatous mitral valve disease at various stages of disease severity.
Topics: Animals; Arginine; Biomarkers; Case-Control Studies; Dog Diseases; Dogs; Echocardiography; Female; Heart Failure; Heart Valve Diseases; Hypertension, Pulmonary; Male; Mitral Valve; Mitral Valve Insufficiency; Mitral Valve Prolapse; Retrospective Studies; Severity of Illness Index | 2020 |
Nitric Oxide-cGMP Pathway Modulation in an Experimental Model of Hypoxic Pulmonary Hypertension.
Topics: Animals; Arginine; Cyclic GMP; Hypertension, Pulmonary; Hypoxia; Male; Myocardium; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Vasodilator Agents | 2021 |
Evaluation of Asymmetric Dimethylarginine Levels in Patients With Chronic Thromboembolic Pulmonary Hypertension Undergoing Pulmonary Endarterectomy.
Topics: Arginine; Chronic Disease; Endarterectomy; Humans; Hypertension, Pulmonary | 2022 |
L-arginine Attenuates Hypobaric Hypoxia-Induced Increase in Ornithine Decarboxylase 1.
Topics: Altitude Sickness; Animals; Arginine; Arterial Pressure; Gene Expression; Hypertension, Pulmonary; Hypoxia; Lung; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Rats; Rats, Sprague-Dawley | 2017 |
Role of plasma asymmetric dimethyl-L-arginine levels in detection of pulmonary hypertension in children with CHD.
Topics: Arginine; Biomarkers; Child, Preschool; Echocardiography; Female; Follow-Up Studies; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Male; Nitric Oxide Synthase; Predictive Value of Tests; Prospective Studies; Pulmonary Wedge Pressure | 2018 |
Asymmetric dimethylarginine levels in children with sickle cell disease and its correlation to tricuspid regurgitant jet velocity.
Topics: Adolescent; Anemia, Sickle Cell; Arginine; Blood Transfusion; Case-Control Studies; Child; Cross-Sectional Studies; Echocardiography, Doppler; Female; Hemolysis; Humans; Hypertension, Pulmonary; Male; Risk Factors; Tricuspid Valve Insufficiency | 2013 |
Effects of dimethylarginine dimethylaminohydrolase-1 overexpression on the response of the pulmonary vasculature to hypoxia.
Topics: Amidohydrolases; Animals; Arginine; Blood Vessels; Cyclic GMP; Gene Expression; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Mice; Nitric Oxide; Nitroarginine; Organ Culture Techniques; Oxadiazoles; Signal Transduction; Vasoconstriction | 2013 |
Intermedin modulates hypoxic pulmonary vascular remodeling by inhibiting pulmonary artery smooth muscle cell proliferation.
Topics: Adrenomedullin; Animals; Apoptosis; Arginine; Cell Proliferation; Endoplasmic Reticulum Stress; Familial Primary Pulmonary Hypertension; Heat-Shock Proteins; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Membrane Glycoproteins; Muscle, Smooth, Vascular; Neuropeptides; Nitric Oxide; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 2014 |
Effect of oral L-arginine administration on exhaled nitric oxide (NO) concentration in healthy volunteers.
Topics: Administration, Oral; Adult; Arginine; Breath Tests; Humans; Hypertension, Pulmonary; Immunoglobulin E; Middle Aged; Nitric Oxide | 2013 |
L-arginine in combination with sildenafil potentiates the attenuation of hypoxic pulmonary hypertension in rats.
Topics: Animals; Arginine; Blood Pressure; Drug Synergism; Drug Therapy, Combination; Hypertension, Pulmonary; Hypoxia; Male; Piperazines; Pulmonary Gas Exchange; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Treatment Outcome; Vasodilator Agents | 2013 |
Exhaled nitric oxide measurement to monitor pulmonary hypertension in a pneumonectomy-monocrotaline rat model.
Topics: Animals; Arginine; Arterial Pressure; Biomarkers; Biopterins; Exhalation; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Nitric Oxide; Pneumonectomy; Pulmonary Artery; Random Allocation; Rats; Rats, Sprague-Dawley | 2013 |
An L-Arginine supplement improves broiler hypertensive response and gut function in broiler chickens reared at high altitude.
Topics: Altitude; Animal Feed; Animals; Arginine; Chickens; Dietary Supplements; Heart Ventricles; Hematocrit; Hypertension, Pulmonary; Ileum; Intestinal Mucosa; Jejunum; Male; Nitric Oxide; Organ Size | 2014 |
Severe pulmonary embolism decreases plasma L-arginine.
Topics: Arginase; Arginine; Chromatography, High Pressure Liquid; Echocardiography, Doppler; Hemolysis; Humans; Hypertension, Pulmonary; Prospective Studies; Pulmonary Embolism; Tricuspid Valve; Tricuspid Valve Insufficiency | 2014 |
Supplemental arginine administered in ovo or in the feed reduces the susceptibility of broilers to pulmonary hypertension syndrome.
Topics: Animals; Arginine; Ascites; Body Weight; Chi-Square Distribution; Chickens; Dietary Supplements; Endothelin-1; Hypertension, Pulmonary; Male; Nitric Oxide; Ovum; Poultry Diseases; Random Allocation; Thyroid Hormones | 2013 |
Increased levels of asymmetric dimethylarginine are associated with pulmonary arterial hypertension in HIV infection.
Topics: Adult; Arginine; Biomarkers; Blood Pressure; Catheterization, Swan-Ganz; Cohort Studies; Echocardiography; Familial Primary Pulmonary Hypertension; Female; HIV Infections; Humans; Hypertension, Pulmonary; Male; Middle Aged; Prospective Studies | 2014 |
Asymmetric dimethylarginine levels in children with β-thalassemia and their correlations to tricuspid regurgitant jet velocity.
Topics: Adolescent; Arginine; beta-Thalassemia; Case-Control Studies; Child; Echocardiography, Doppler; Female; Follow-Up Studies; Humans; Hypertension, Pulmonary; Male; Prognosis; Risk Factors; Tricuspid Valve Insufficiency | 2014 |
NPY/Y₁ receptor-mediated vasoconstrictory and proliferative effects in pulmonary hypertension.
Topics: Adult; Animals; Arginine; Cell Proliferation; Epinephrine; Female; Humans; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Indoles; Lung; Male; Mice, Inbred C57BL; Monocrotaline; Myocytes, Smooth Muscle; Neuropeptide Y; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Vasoconstriction; Vasoconstrictor Agents; Young Adult | 2014 |
Naringenin adds to the protective effect of L-arginine in monocrotaline-induced pulmonary hypertension in rats: favorable modulation of oxidative stress, inflammation and nitric oxide.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Caspase 3; Flavanones; Hypertension, Pulmonary; Inflammation; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Pulmonary Artery; Rats, Wistar; Tumor Necrosis Factor-alpha | 2014 |
miR-21/DDAH1 pathway regulates pulmonary vascular responses to hypoxia.
Topics: Amidohydrolases; Animals; Arginine; Cells, Cultured; Cyclic GMP; Endothelial Cells; Familial Primary Pulmonary Hypertension; Humans; Hypertension, Pulmonary; Hypoxia; Lung; Male; Mice; Mice, Transgenic; MicroRNAs; Myocytes, Smooth Muscle | 2014 |
A common polymorphism in extracellular superoxide dismutase affects cardiopulmonary disease risk by altering protein distribution.
Topics: Animals; Antioxidants; Arginine; Bronchoalveolar Lavage Fluid; Genetic Predisposition to Disease; Genotype; Glycine; Heparin; Humans; Hypertension, Pulmonary; Lung; Mice; Mice, Inbred C57BL; Mice, Transgenic; Polymorphism, Single Nucleotide; Risk Factors; Sepharose; Sequence Analysis, DNA; Superoxide Dismutase | 2014 |
Plasma asymmetric dimethylarginine levels are increased in neonates with bronchopulmonary dysplasia-associated pulmonary hypertension.
Topics: Arginine; Bronchopulmonary Dysplasia; Case-Control Studies; Humans; Hypertension, Pulmonary; Infant, Newborn | 2015 |
Plasma asymmetric dimethylarginine in infants with bronchopulmonary dysplasia: a promising biomarker despite uncertain pathogenic significance.
Topics: Arginine; Bronchopulmonary Dysplasia; Humans; Hypertension, Pulmonary | 2015 |
Pulmonary hypertension in well-transfused thalassemia major patients.
Topics: Adolescent; Adult; Arginine; beta-Thalassemia; Erythrocyte Transfusion; Female; Hemolysis; Humans; Hypertension, Pulmonary; Iron; Iron Overload; Male; Risk Factors; Tricuspid Valve Insufficiency; Ultrasonography | 2015 |
Rescue Treatment with L-Citrulline Inhibits Hypoxia-Induced Pulmonary Hypertension in Newborn Pigs.
Topics: Animals; Animals, Newborn; Arginine; Cell Hypoxia; Citrulline; Drug Evaluation, Preclinical; Hypertension, Pulmonary; Sus scrofa | 2015 |
Arginase inhibition prevents bleomycin-induced pulmonary hypertension, vascular remodeling, and collagen deposition in neonatal rat lungs.
Topics: Aminocaproates; Animals; Antibiotics, Antineoplastic; Arginase; Arginine; Bleomycin; Boron Compounds; Bronchopulmonary Dysplasia; Collagen; Disease Models, Animal; Hypertension, Pulmonary; Lung; Lung Injury; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2015 |
Asymmetric Dimethyl-L-Arginine is a Biomarker for Disease Stage and Follow-Up of Pulmonary Hypertension Associated with Congenital Heart Disease.
Topics: Adult; Arginine; Biomarkers; Female; Follow-Up Studies; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Male; Middle Aged; Prospective Studies; Pulmonary Artery; Sildenafil Citrate; Treatment Outcome; Vascular Resistance; Vasodilator Agents; Young Adult | 2015 |
Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia.
Topics: Adult; Arginase; Arginine; Case-Control Studies; Cross-Sectional Studies; Echocardiography, Doppler; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Thalassemia; Young Adult | 2015 |
L-arginine supplementation of reduced-protein diets improves pulmonary hypertensive response in broiler chickens reared at high altitude.
Topics: Altitude; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Diet, Protein-Restricted; Dietary Supplements; Hypertension, Pulmonary; Male; Poultry Diseases; Random Allocation | 2015 |
Asymmetric dimethyl arginine induces pulmonary vascular dysfunction via activation of signal transducer and activator of transcription 3 and stabilization of hypoxia-inducible factor 1-alpha.
Topics: Amidohydrolases; Arginine; Calcium; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Hypertension, Pulmonary; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation Mediators; Intercellular Adhesion Molecule-1; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Signal Transduction; STAT3 Transcription Factor | 2015 |
A Biochemical Approach to Understand the Pathogenesis of Advanced Pulmonary Arterial Hypertension: Metabolomic Profiles of Arginine, Sphingosine-1-Phosphate, and Heme of Human Lung.
Topics: Adult; Arginine; Female; Heme; Humans; Hypertension, Pulmonary; Lung; Lysophospholipids; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Nitric Oxide; Sphingosine; Vascular Remodeling | 2015 |
Metabolic Profiling of Right Ventricular-Pulmonary Vascular Function Reveals Circulating Biomarkers of Pulmonary Hypertension.
Topics: Adult; Aged; Animals; Arginine; Arterial Pressure; Biomarkers; Female; Humans; Hypertension, Pulmonary; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Mice; Middle Aged; Nitric Oxide; Pulmonary Circulation; Purines; Reproducibility of Results; Statistics as Topic; Tricarboxylic Acids; Vascular Resistance; Ventricular Dysfunction, Right | 2016 |
The Quest for Metabolic Biomarkers of Pulmonary Hypertension.
Topics: Animals; Arginine; Female; Humans; Hypertension, Pulmonary; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Nitric Oxide; Purines; Tricarboxylic Acids; Ventricular Dysfunction, Right | 2016 |
Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?
Topics: Altitude Sickness; Amidohydrolases; Animals; Arginine; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Pulmonary Circulation; Rats; Rats, Wistar; Signal Transduction; Time Factors; Vascular Resistance | 2016 |
An arginase-1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO-mediated apoptosis in lymphocytes.
Topics: Apoptosis; Arginase; Arginine; Bronchopulmonary Dysplasia; Caspase 3; Cohort Studies; Humans; Hypertension, Pulmonary; Infant, Newborn; Lymphocytes; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Polymorphism, Single Nucleotide; Urea | 2016 |
[Clinical value of ADMA in patients with pulmonary arterial hypertension combination with congenital heart disease].
Topics: Adult; Arginine; Biomarkers; Echocardiography; Female; Heart Defects, Congenital; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Prognosis; Sensitivity and Specificity; Sildenafil Citrate | 2017 |
L-arginine plasma levels and severity of idiopathic pulmonary arterial hypertension.
Topics: Adult; Aged; Arginine; Biomarkers; Blood Pressure; Cardiac Catheterization; Chromatography, High Pressure Liquid; Citrulline; Cohort Studies; Exercise Test; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Male; Middle Aged; Pilot Projects; Pulmonary Artery; Severity of Illness Index | 2008 |
Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension.
Topics: AC133 Antigen; Aged; Antigens, CD; Antigens, CD34; Arginine; Cells, Cultured; Cyclic GMP; Down Syndrome; Eisenmenger Complex; Endothelium, Vascular; Exercise; Female; Flow Cytometry; Glycoproteins; Hematopoietic Stem Cells; Humans; Hypertension, Pulmonary; Inflammation Mediators; Male; Middle Aged; Natriuretic Peptide, Brain; Peptides; Piperazines; Pulmonary Artery; Purines; Sildenafil Citrate; Stem Cells; Sulfones; Vascular Endothelial Growth Factor Receptor-2; Vasodilator Agents | 2008 |
Association of asymmetric dimethylarginine with sickle cell disease-related pulmonary hypertension.
Topics: Adult; Anemia, Sickle Cell; Arginine; Biomarkers; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged | 2008 |
Asymmetrical dimethylarginine in systemic sclerosis-related pulmonary arterial hypertension.
Topics: Aged; Analysis of Variance; Arginine; Case-Control Studies; Echocardiography; Echocardiography, Doppler; Exercise Test; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Respiratory Function Tests; Scleroderma, Systemic | 2008 |
Procedure-related pulmonary hypertension in patients with hepatocellular carcinoma undergoing percutaneous ethanol injection--role of ethanol, hemolysis, asymmetric dimethylarginine, and the nitric oxide system.
Topics: Aged; Arginine; Carcinoma, Hepatocellular; Cross-Sectional Studies; Ethanol; Female; Hemolysis; Humans; Hypertension, Pulmonary; Injections; Liver Neoplasms; Male; Nitric Oxide | 2009 |
Endogenous nitric oxide synthase inhibitors in sickle cell disease: abnormal levels and correlations with pulmonary hypertension, desaturation, haemolysis, organ dysfunction and death.
Topics: Anemia, Sickle Cell; Arginine; Case-Control Studies; Citrulline; Follow-Up Studies; Hemolysis; Humans; Hypertension, Pulmonary; Kidney Diseases; Linear Models; Nitric Oxide Synthase; omega-N-Methylarginine; Oxygen; Proportional Hazards Models; Risk; Survival Rate | 2009 |
L-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension.
Topics: Animals; Arginine; Body Weight; Chronic Disease; Hematocrit; Hypertension, Pulmonary; Hypoxia; Male; Neovascularization, Physiologic; Nitric Oxide; Pulmonary Circulation; Rats; Rats, Inbred WKY; Vascular Endothelial Growth Factor A | 2009 |
[Effect of apelin on hypoxic pulmonary hypertension in rats: role of the NO pathway].
Topics: Animals; Arginine; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Intercellular Signaling Peptides and Proteins; Male; Nitric Oxide Synthase Type II; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Signal Transduction | 2009 |
Plasma asymmetric dimethylarginine concentrations in sickle cell disease are related to the hemolytic phenotype.
Topics: Adult; Albuminuria; Anemia, Sickle Cell; Arginine; beta-Thalassemia; Cholelithiasis; Female; Hemolysis; Humans; Hypertension, Pulmonary; Leg Ulcer; Male; Middle Aged; Nitric Oxide; Osteonecrosis; Phenotype; Priapism; Retinal Diseases; Sickle Cell Trait; Young Adult | 2010 |
L-arginine restores endothelial nitric oxide synthase-coupled activity and attenuates monocrotaline-induced pulmonary artery hypertension in rats.
Topics: Animals; Arginine; Blood Pressure; Blotting, Western; Body Weight; HSP90 Heat-Shock Proteins; Hypertension, Pulmonary; Immunoprecipitation; Kaplan-Meier Estimate; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 2010 |
Left atrial volume and N-terminal pro-B type natriuretic peptide are associated with elevated pulmonary artery pressure in patients with systemic sclerosis.
Topics: Aged; Arginine; Biomarkers; Blood Pressure; Cross-Sectional Studies; Female; Follow-Up Studies; Heart Atria; Humans; Hypertension, Pulmonary; Male; Middle Aged; Multivariate Analysis; Natriuretic Peptide, Brain; Peptide Fragments; Predictive Value of Tests; Prospective Studies; Pulmonary Artery; Scleroderma, Systemic; Ultrasonography; Ventricular Dysfunction, Right | 2010 |
Effects of atorvastatin and L-arginine treatments on electrical field stimulation-mediated relaxations in pulmonary arterial rings of monocrotaline-induced pulmonary hypertensive rats.
Topics: Animals; Arginine; Atorvastatin; Electric Stimulation; Endothelium, Vascular; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; In Vitro Techniques; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Vasodilation | 2010 |
L-citrulline attenuates arrested alveolar growth and pulmonary hypertension in oxygen-induced lung injury in newborn rats.
Topics: Animals; Animals, Newborn; Arginine; Bronchopulmonary Dysplasia; Citrulline; Disease Models, Animal; Humans; Hypertension, Pulmonary; Infant, Newborn; Lung; Lung Injury; Nitric Oxide; Pulmonary Alveoli; Rats | 2010 |
Bosentan and improved pulmonary endothelial function in pulmonary arterial hypertension.
Topics: Acetylcholine; Aged; Antihypertensive Agents; Arginine; Bosentan; Endothelium, Vascular; Familial Primary Pulmonary Hypertension; Female; Humans; Hypertension, Pulmonary; Lung; Male; Middle Aged; Nitroprusside; omega-N-Methylarginine; Pulmonary Artery; Sulfonamides; Ultrasonography | 2010 |
Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.
Topics: Arginine; Biomarkers; Down Syndrome; Female; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates; Nitrites | 2011 |
cAMP phosphodiesterase inhibitors increases nitric oxide production by modulating dimethylarginine dimethylaminohydrolases.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amidohydrolases; Apoptosis; Arginine; Cell Proliferation; Cell Survival; Cells, Cultured; Cyclic GMP; Cytokines; Endothelial Cells; Hemodynamics; Humans; Hypertension, Pulmonary; Naphthyridines; Nitric Oxide; Phosphodiesterase Inhibitors; Promoter Regions, Genetic; Pulmonary Gas Exchange | 2011 |
Targeting dimethylarginine dimethylaminohydrolases in pulmonary arterial hypertension: a new approach to improve vascular dysfunction?
Topics: Amidohydrolases; Arginine; Humans; Hypertension, Pulmonary; Naphthyridines; Nitric Oxide; Nitric Oxide Synthase; Phosphodiesterase Inhibitors | 2011 |
Effects of oral supplementation of L-arginine in the treatment of pulmonary hypertension secondary to pulmonary embolism: a case report.
Topics: Administration, Oral; Arginine; Dietary Supplements; Female; Heart Failure; Humans; Hypertension, Pulmonary; Middle Aged; Natriuretic Peptide, Brain; Pulmonary Embolism | 2010 |
Rosuvastatin attenuates monocrotaline-induced pulmonary hypertension via regulation of Akt/eNOS signaling and asymmetric dimethylarginine metabolism.
Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Body Weight; Fluorobenzenes; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Nitric Oxide Synthase Type III; Organ Size; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Signal Transduction; Sulfonamides; Ventricular Dysfunction, Right | 2011 |
The impact of L-NAME and L-arginine chronic toxicity induced lesions on ascites--pulmonary hypertension syndrome development in broiler chickens.
Topics: Animals; Arginine; Ascites; Chickens; Hemorrhage; Hypertension, Pulmonary; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Poultry Diseases; Toxicity Tests, Chronic | 2011 |
Arginase depletes plasma l-arginine and decreases pulmonary vascular reserve during experimental pulmonary embolism.
Topics: Animals; Arginase; Arginine; Blood Pressure; Cardiac Output; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Hemoglobins; Hemolysis; Hypertension, Pulmonary; Lactic Acid; Male; Microspheres; Pulmonary Circulation; Pulmonary Embolism; Rats; Rats, Sprague-Dawley; Vascular Resistance; Vasoconstriction | 2012 |
Pulmonary hypertension associated with advanced systolic heart failure: dysregulated arginine metabolism and importance of compensatory dimethylarginine dimethylaminohydrolase-1.
Topics: Aged; Amidohydrolases; Arginine; Disease Progression; Female; Heart Failure, Systolic; Humans; Hypertension, Pulmonary; Male; Middle Aged | 2012 |
Elevated homocysteine and asymmetric dimethyl arginine levels in pulmonary hypertension associated with congenital heart disease.
Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiac Catheterization; Case-Control Studies; Child; Child, Preschool; Echocardiography; Enzyme-Linked Immunosorbent Assay; Familial Primary Pulmonary Hypertension; Heart Defects, Congenital; Hemodynamics; Homocysteine; Humans; Hypertension, Pulmonary; Infant; Nitric Oxide; Predictive Value of Tests; ROC Curve; Sensitivity and Specificity; Statistics, Nonparametric | 2012 |
Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.
Topics: Acetylcarnitine; Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Arginine; Biopterins; Disease Models, Animal; Endothelial Cells; Female; GTP Cyclohydrolase; HSP70 Heat-Shock Proteins; Hypertension, Pulmonary; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pulmonary Artery; Pulmonary Heart Disease; Sheep; Signal Transduction; Ubiquitin-Protein Ligases; Ubiquitination | 2012 |
Potential treatment influences and mechanisms related to asymmetric dimethylarginine control in heart failure.
Topics: Amidohydrolases; Arginine; Female; Heart Failure, Systolic; Humans; Hypertension, Pulmonary; Male | 2012 |
Assessment of the endothelial functions in monocrotaline-induced pulmonary hypertension.
Topics: Animals; Aorta, Thoracic; Arginine; Disease Models, Animal; Endothelium, Vascular; Hydrogen Sulfide; Hypertension, Pulmonary; Iloprost; Male; Monocrotaline; Nitric Oxide; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents | 2013 |
Increased exhaled nitric oxide levels after exercise in patients with chronic systolic heart failure with pulmonary venous hypertension.
Topics: Arginine; Biomarkers; Endothelium, Vascular; Exercise; Exercise Test; Exhalation; Female; Heart Failure, Systolic; Humans; Hypertension, Pulmonary; Male; Middle Aged; Multivariate Analysis; Nitric Oxide; Oxidative Stress; Surveys and Questionnaires; Time Factors; Ultrasonography | 2012 |
Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous L-arginine.
Topics: Animals; Arginine; Blood Pressure; Chronic Disease; Citrulline; Compliance; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Perfusion; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance; Vasoconstriction; Ventricular Dysfunction, Right | 2013 |
Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow.
Topics: Adenosine Triphosphate; Animals; Arginine; Carnitine; Disease Models, Animal; Endothelial Cells; Heart Defects, Congenital; Homeostasis; Hypertension, Pulmonary; Lung; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Circulation; Regional Blood Flow; Sheep; Signal Transduction | 2013 |
Pulmonary hypertension associated with diffuse deposition of pentosidine in pulmonary arterioles.
Topics: Aged; Arginine; Diabetes Mellitus; Female; Humans; Hypertension, Pulmonary; Lysine | 2013 |
The modulating effect of L-arginine on collagen metabolism of pulmonary artery in pulmonary hypertension induced by a left-to-right shunt.
Topics: Animals; Arginine; Collagen; Collagen Type I; Collagen Type III; Hypertension, Pulmonary; Immunohistochemistry; In Situ Hybridization; Lung; Male; Matrix Metalloproteinase 1; Pulmonary Artery; Pulmonary Wedge Pressure; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1 | 2002 |
L-arginine impacts pulmonary vascular structure in rats with an aortocaval shunt.
Topics: Animals; Aorta; Apoptosis; Arginine; Arteriovenous Shunt, Surgical; Cell Division; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Pulmonary Circulation; Pulmonary Wedge Pressure; Rats; Rats, Sprague-Dawley; Vena Cava, Inferior | 2002 |
Metabolism of asymmetric dimethylarginines is regulated in the lung developmentally and with pulmonary hypertension induced by hypobaric hypoxia.
Topics: Amidohydrolases; Animals; Animals, Newborn; Arginine; Hypertension, Pulmonary; Hypoxia; Immunohistochemistry; Lung; Male; Pressure; Protein Isoforms; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swine | 2003 |
Treatment of pulmonary hypertension.
Topics: Administration, Inhalation; Antihypertensive Agents; Arginine; Endothelin Receptor Antagonists; Enzyme Inhibitors; Humans; Hypertension, Pulmonary; Nitric Oxide | 2003 |
[The effects of long-term application of L-arginine on K+ channel in pulmonary artery smooth muscle cells from rats exposed to chronic hypoxia].
Topics: Animals; Arginine; Hypertension, Pulmonary; Hypoxia; Male; Membrane Potentials; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Potassium Channels, Voltage-Gated; Pulmonary Artery; Random Allocation; Rats; Rats, Wistar | 2003 |
Endogenous NO does not regulate baseline pulmonary pressure, but reduces acute pulmonary hypertension in dogs.
Topics: Acute Disease; Animals; Arginine; Blood Pressure; Dogs; Enzyme Inhibitors; Female; Hypertension, Pulmonary; Hypoxia; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Alveoli | 2003 |
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Chronic Disease; Disease Models, Animal; Enzyme Activation; Hypertension, Pulmonary; Hypoxia; Isoenzymes; Lung; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Sprague-Dawley | 2003 |
Nitric oxide formation and plasma L-arginine levels in pulmonary hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Body Weight; Endothelin-1; Endothelium, Vascular; Hypertension, Pulmonary; Male; Nitrates; Nitric Oxide; Pulmonary Artery; Rats; Rats, Wistar | 2004 |
New therapies for pulmonary hypertension in neonates and children.
Topics: Antihypertensive Agents; Arginine; Child; Endothelin-1; Epoprostenol; Exercise Tolerance; Humans; Hypertension, Pulmonary; Infant, Newborn | 2004 |
Management of Eisenmenger syndrome in pregnancy with sildenafil and L-arginine.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adult; Arginine; Drug Therapy, Combination; Eisenmenger Complex; Female; Humans; Hypertension, Pulmonary; Patient Care Team; Phosphodiesterase Inhibitors; Piperazines; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Purines; Sildenafil Citrate; Sulfones | 2004 |
In vitro hypoxia differentially affects constriction and relaxation responses of isolated pulmonary arteries from broiler and leghorn chickens.
Topics: Acetylcholine; Animals; Arginine; Body Weight; Chickens; Endothelin-1; Endothelium, Vascular; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Organ Size; Oxygen; Potassium Chloride; Poultry Diseases; Pulmonary Artery | 2004 |
Effects of long-term captopril and L-arginine treatment on ventilation and blood pressure in obese male SHHF rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Captopril; Hypertension, Pulmonary; Hypoventilation; Male; Obesity; Oxygen Consumption; Pulmonary Ventilation; Rats; Treatment Outcome | 2004 |
Inhibition of expression of hypoxia-inducible factor-1alpha mRNA by nitric oxide in hypoxic pulmonary hypertension rats.
Topics: Animals; Arginine; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2004 |
Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop.
Topics: Adult; Animals; Arginine; Bone Morphogenetic Protein Receptors, Type II; Enzyme Inhibitors; Female; Forecasting; Genetic Predisposition to Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Pulmonary; Male; Models, Biological; Pancreatic Elastase; Platelet Aggregation Inhibitors; Potassium Channels; Protein Serine-Threonine Kinases; Rats; Research; Signal Transduction | 2004 |
Spontaneous atrioventricular groove disruption during off-pump coronary artery bypass grafting.
Topics: Aged; Anticoagulants; Arginine; Cardiopulmonary Bypass; Coronary Artery Bypass, Off-Pump; Coronary Stenosis; Emergencies; Fatal Outcome; Female; Heart Injuries; Heparin; Humans; Hypertension, Pulmonary; Internal Mammary-Coronary Artery Anastomosis; Intraoperative Complications; Mitral Valve; Myocardial Infarction; Pipecolic Acids; Postoperative Complications; Rupture, Spontaneous; Sulfonamides; Suture Techniques; Thrombocytopenia; Thromboembolism | 2005 |
l-Arginine attenuates acute pulmonary embolism-induced oxidative stress and pulmonary hypertension.
Topics: Acute Disease; Animals; Arginine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pulmonary Artery; Pulmonary Embolism; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2005 |
Elevated levels of asymmetric di-methylarginine in neonates with congenital diaphragmatic hernia.
Topics: Arginine; Case-Control Studies; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pulmonary; Infant, Newborn; Nitric Oxide Synthase | 2005 |
Plasma L-arginine and metabolites of nitric oxide synthase in patients with left-to-right shunt after intracardiac repair.
Topics: Adolescent; Adult; Arginine; Cardiopulmonary Bypass; Child; Child, Preschool; Cyclic GMP; Female; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant; Male; Nitric Oxide Synthase | 2005 |
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension.
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Humans; Hypertension, Pulmonary; Isoenzymes; Lung; Male; Monocrotaline; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2005 |
Effect of L-arginine on collagen of high flow-induced pulmonary arterial remodeling.
Topics: Animals; Arginine; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypertension, Pulmonary; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 2005 |
Asymmetrical dimethylarginine in idiopathic pulmonary arterial hypertension.
Topics: Adult; Arginine; Biomarkers; Cardiac Catheterization; Female; Follow-Up Studies; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nitric Oxide Synthase Type III; Pulmonary Circulation; Stroke Volume; Survival Analysis; Vascular Resistance | 2005 |
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease.
Topics: Adult; Aged; Amino Acids; Anemia, Sickle Cell; Arginase; Arginine; Case-Control Studies; Female; Humans; Hypertension, Pulmonary; Male; Middle Aged; Nitric Oxide; Ornithine; Proportional Hazards Models | 2005 |
A urinary test for pulmonary arterial hypertension?
Topics: Antihypertensive Agents; Arginine; Bosentan; Humans; Hypertension, Pulmonary; Nitric Oxide; Pulmonary Artery; Sulfonamides | 2005 |
L-Arginine inhibiting pulmonary vascular remodelling is associated with promotion of apoptosis in pulmonary arterioles smooth muscle cells in broilers.
Topics: Animals; Apoptosis; Arginine; Arterioles; Body Weight; Chickens; Cold Temperature; Female; Hypertension, Pulmonary; Lung; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Poultry Diseases; Pulmonary Artery | 2005 |
L-Arginine prevents air embolism-induced acute lung injury in rats.
Topics: Acute Disease; Animals; Arginine; Bronchoalveolar Lavage; Capillary Permeability; Disease Models, Animal; Embolism, Air; Hypertension, Pulmonary; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Organ Size; Proteins; Pulmonary Edema; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA.
Topics: Arginine; Atherosclerosis; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Proteins; Cardiovascular Diseases; Cell Culture Techniques; Endothelial Cells; Gene Expression Profiling; Gene Expression Regulation; Humans; Hypertension, Pulmonary; Oligonucleotide Array Sequence Analysis; Protein-Arginine N-Methyltransferases; Smad5 Protein; Transforming Growth Factor beta | 2005 |
Hemodynamic effects of combined sildenafil and L-arginine during acute pulmonary embolism-induced pulmonary hypertension.
Topics: Acute Disease; Analysis of Variance; Animals; Arginine; Blood Pressure; Cyclic GMP; Dogs; Female; Heart Rate; Hypertension, Pulmonary; Infusions, Intravenous; Male; Nitrates; Nitrites; Piperazines; Pulmonary Artery; Pulmonary Embolism; Purines; Respiration; Sildenafil Citrate; Sulfones; Time Factors; Vasodilator Agents | 2005 |
Arginine metabolism, pulmonary hypertension, and sickle cell disease.
Topics: Anemia, Sickle Cell; Arginase; Arginine; Citrulline; Dietary Supplements; Humans; Hypertension, Pulmonary | 2005 |
Arginine metabolism, pulmonary hypertension, and sickle cell disease.
Topics: Anemia, Sickle Cell; Arginase; Arginine; Humans; Hypertension, Pulmonary; Nitric Oxide Synthase | 2005 |
Hemolysis-associated pulmonary hypertension in thalassemia.
Topics: alpha-Thalassemia; Arginase; Arginine; Endothelium, Vascular; Erythrocytes; Hemoglobin E; Hemolysis; Humans; Hypertension, Pulmonary; Nitric Oxide; Ornithine; Thalassemia; Tricuspid Valve | 2005 |
Citrulline, Viagra and BiDil--bad medicine.
Topics: Adult; Arginine; Chronic Disease; Citrulline; Cyclic GMP; Endothelium, Vascular; Erectile Dysfunction; Humans; Hypertension, Pulmonary; Infant; Male; Marketing; Nitric Oxide; Piperazines; Purines; Sildenafil Citrate; Sulfones; Vasodilator Agents | 2005 |
New strategies for the treatment of pulmonary hypertension in sickle cell disease : the rationale for arginine therapy.
Topics: Anemia, Sickle Cell; Arginase; Arginine; Humans; Hypertension, Pulmonary; Nitric Oxide; Prospective Studies | 2006 |
L-arginine and pulmonary embolism.
Topics: Animals; Arginine; Dogs; Embolism, Air; Hypertension, Pulmonary; Pulmonary Embolism; Rats | 2006 |
Changes in pulmonary arteriole protein kinase calpha expression associated with supplemental L-arginine in broilers during cool temperature exposure.
Topics: Animals; Arginine; Chickens; Cold Temperature; Dietary Supplements; Female; Gene Expression Regulation, Enzymologic; Hypertension, Pulmonary; Male; Nitric Oxide; Poultry Diseases; Protein Kinase C-alpha; Pulmonary Artery | 2006 |
Impact of L-arginine on hydrogen sulfide/cystathionine-gamma-lyase pathway in rats with high blood flow-induced pulmonary hypertension.
Topics: Animals; Arginine; Blood Flow Velocity; Cystathionine gamma-Lyase; Gene Expression Regulation; Hydrogen Sulfide; Hypertension, Pulmonary; Male; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats.
Topics: Amidohydrolases; Animals; Arginase; Arginine; Cyclic GMP; Endothelial Cells; Enzyme Activation; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Isometric Contraction; Lung; Male; Monocrotaline; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Vasoconstriction | 2007 |
Asymmetric dimethylarginine is increased in chronic thromboembolic pulmonary hypertension.
Topics: Aged; Arginine; Chronic Disease; Endothelial Cells; Enzyme Inhibitors; Female; Humans; Hypertension, Pulmonary; Kaplan-Meier Estimate; Male; Middle Aged; Nitric Oxide Synthase; Osmolar Concentration; Prognosis; Pulmonary Artery; Severity of Illness Index; Thromboembolism | 2007 |
Partial reversal of hemolysis-associated pulmonary arterial hypertension in response to oral administration of L-arginine in a patient with hereditary spherocytosis.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Arginine; Aspirin; Hemolysis; Humans; Hypertension, Pulmonary; Male; Middle Aged; Spherocytosis, Hereditary; Vasodilator Agents; Warfarin | 2007 |
Acute administration of l-arginine restores nitric oxide-mediated relaxation in isolated pulmonary arteries from pulmonary hypertensive exercise trained rats.
Topics: Animals; Arginine; Hypertension, Pulmonary; In Vitro Techniques; Male; Nitric Oxide; Nitroprusside; Physical Conditioning, Animal; Pulmonary Artery; Rats; Rats, Wistar; Vasodilation | 2008 |
Endothelin-1 and asymmetric dimethylarginine in children with left-to-right shunt after intracardiac repair.
Topics: Adolescent; Adult; Arginine; Biomarkers; Cardiopulmonary Bypass; Child; Child, Preschool; Endothelin-1; Female; Humans; Hypertension, Pulmonary; Infant; Male; Nitric Oxide Synthase; Pancreatitis-Associated Proteins; Postoperative Complications; Prospective Studies; Statistics, Nonparametric; Time Factors; Treatment Outcome; Young Adult | 2008 |
Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Perfusion; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Substance P; Vasodilation | 1993 |
Attenuation of chronic hypoxic pulmonary hypertension in rats by cyclooxygenase products and by nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arachidonic Acid; Arginine; Blood Pressure; Dilatation; Dinoprost; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Rats; Rats, Wistar | 1993 |
Effect of nitric oxide synthase inhibition during group B streptococcal sepsis in neonatal piglets.
Topics: Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Hemodynamics; Hypertension, Pulmonary; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pulmonary Gas Exchange; Sepsis; Streptococcal Infections; Streptococcus agalactiae; Swine | 1994 |
L-arginine-related responses to pressure and vasoactive agents in monocrotaline-treated rat pulmonary arteries.
Topics: Air Pressure; Animals; Arginine; Calcium; Enzyme Inhibitors; Hypertension, Pulmonary; Male; Monocrotaline; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 1995 |
Protamine-induced pulmonary venoconstriction in heparinized pigs.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Central Venous Pressure; Disease Models, Animal; Female; Heparin; Hypertension, Pulmonary; Male; Nitric Oxide; Nitroarginine; Protamines; Pulmonary Artery; Pulmonary Veins; Pulmonary Wedge Pressure; Swine; Vascular Resistance; Vasoconstrictor Agents | 1995 |
Short-term pulmonary vasodilation with L-arginine in pulmonary hypertension.
Topics: Adult; Aged; Arginine; Epoprostenol; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung; Male; Middle Aged; Nitric Oxide; Vasodilation | 1995 |
Evidence that nitric oxide from the endothelium attenuates inherent tone in isolated pulmonary arteries from rats with hypoxic pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Dose-Response Relationship, Drug; Endothelium; Hypertension, Pulmonary; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Pulmonary Artery; Rats; Rats, Wistar | 1995 |
[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats].
Topics: Animals; Arginine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Nifedipine; Nitrendipine; Rats; Rats, Sprague-Dawley | 1994 |
Inhaled nitric oxide does not alter the longitudinal distribution of pulmonary vascular resistance.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Administration, Inhalation; Animals; Arginine; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Endoperoxides, Synthetic; Pulmonary Wedge Pressure; Rabbits; Respiration, Artificial; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents | 1995 |
Supplemental L-arginine attenuates pulmonary hypertension syndrome (ascites) in broilers.
Topics: Animals; Arginine; Chickens; Food, Fortified; Hypertension, Pulmonary; Male; Poultry Diseases | 1995 |
Endothelinb receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Arginine; Blood Pressure; Disease Models, Animal; Endothelins; Endothelium, Vascular; Glyburide; Hypertension, Pulmonary; Injections, Intra-Arterial; Nitroarginine; Peptide Fragments; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Regional Blood Flow; Sheep; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents; Vasodilation | 1995 |
[Effect of NG-nitro-L-arginine methylester on the secretion of endothelin-1 in vivo and in cultured endothelial cells].
Topics: Animals; Arginine; Cells, Cultured; Dogs; Endothelins; Endothelium, Vascular; Female; Humans; Hypertension, Pulmonary; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Umbilical Veins | 1995 |
Developmental effects of endothelin-1 on the pulmonary circulation in sheep.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Arginine; Endothelins; Glyburide; Hemodynamics; Hypertension, Pulmonary; Meclofenamic Acid; Nitric Oxide; Nitroarginine; Potassium Channel Blockers; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pulmonary Circulation; Sheep; Thromboxane A2; Vasoconstrictor Agents | 1994 |
[Inhibition of endogenous nitric oxide synthesis enhances acute hypoxic pulmonary vasoconstriction].
Topics: Animals; Arginine; Blood Pressure; Dogs; Hypertension, Pulmonary; Hypoxia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Artery; Vascular Resistance; Vasoconstriction | 1994 |
Vasodilatory effects of ketamine on pulmonary arteries in rats with chronic hypoxic pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Dinoprost; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Ketamine; Male; Nitric Oxide; Nitroarginine; Nitroprusside; Pulmonary Artery; Rats; Rats, Wistar; Vasodilation | 1995 |
The pulmonary effect of nitric oxide synthase inhibition following endotoxemia in a swine model.
Topics: Administration, Inhalation; Animals; Arginine; Bacteremia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli Infections; Female; Hypertension, Pulmonary; Hypoxia; Lung Volume Measurements; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Edema; Pulmonary Wedge Pressure; Random Allocation; Swine | 1994 |
Effect of l-glutamine on pulmonary hypertension in the perfused rabbit lung.
Topics: Animals; Arginine; Blood Pressure; Glutamine; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Pulmonary Artery; Rabbits | 1994 |
Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation.
Topics: Animals; Arginine; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Fetus; Hypertension, Pulmonary; Muscle Tonus; Nitric Oxide; Nitroarginine; Peptides, Cyclic; Perfusion; Protein Precursors; Pulmonary Circulation; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Sheep; Vascular Resistance; Viper Venoms | 1994 |
Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Arginine; Endothelins; Glyburide; Hypertension, Pulmonary; Hypoxia; Injections, Intra-Arterial; Meclofenamic Acid; Nitroarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Rest; Sheep; Vasodilation | 1993 |
M&B 22948, a cGMP phosphodiesterase inhibitor, is a pulmonary vasodilator in lambs.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Animals, Newborn; Arginine; Hypertension, Pulmonary; Hypoxia; Infusions, Intravenous; Nitroarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Purinones; Sheep; Vasodilator Agents | 1993 |
L-arginine infusion has no effect on systemic haemodynamics in normal volunteers, or systemic and pulmonary haemodynamics in patients with elevated pulmonary vascular resistance.
Topics: Adult; Arginine; Blood Pressure; Cyclic GMP; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Male; Pulmonary Circulation; Pulse; Sclerosis; Skin Temperature; Vascular Resistance | 1993 |
Nitric oxide inhalation attenuates pulmonary hypertension and improves gas exchange in endotoxin shock.
Topics: Administration, Inhalation; Animals; Arginine; Blood Gas Analysis; Blood Pressure; Endothelins; Female; Hemodynamics; Hypertension, Pulmonary; Male; Neuropeptide Y; Nitric Oxide; Nitroarginine; Norepinephrine; Pulmonary Circulation; Pulmonary Gas Exchange; Shock, Septic; Swine; Vascular Resistance | 1993 |
Hyperoxia and alkalosis produce pulmonary vasodilation independent of endothelium-derived nitric oxide in newborn lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkalosis; Animals; Animals, Newborn; Arginine; Hypertension, Pulmonary; Nitric Oxide; Nitroarginine; Oxygen; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Sheep; Vasodilation | 1993 |
Endothelium-dependent relaxations in sheep pulmonary arteries and veins: resistance to block by NG-nitro-L-arginine in pulmonary hypertension.
Topics: Animals; Arginine; Blood Gas Analysis; Endothelium, Vascular; Enzyme Inhibitors; Female; Hemodynamics; Hypertension, Pulmonary; In Vitro Techniques; Ionomycin; Ionophores; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Potassium Channels; Potassium Chloride; Pulmonary Artery; Pulmonary Veins; Sheep; Up-Regulation; Vasodilator Agents | 1995 |
Role of nitric oxide and endothelin-1 in monocrotaline-induced pulmonary hypertension in rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Calcimycin; Dose-Response Relationship, Drug; Endothelins; Endothelium, Vascular; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; In Vitro Techniques; Indomethacin; Male; Monocrotaline; Nitric Oxide; Nitroglycerin; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 1995 |
Endogenous nitric oxide and pulmonary vascular tone in the neonate.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Extracorporeal Membrane Oxygenation; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Respiratory Mechanics; Swine; Vascular Resistance | 1996 |
Effects of pulmonary hypertension on vasoconstrictor responses to endothelin-1 and sarafotoxin S6C and on inherent tone in rat pulmonary arteries.
Topics: Animals; Arginine; Endothelins; Endothelium, Vascular; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Pulmonary Artery; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms | 1995 |
Effects of cardiopulmonary bypass and circulatory arrest on endothelium-dependent vasodilation in the lung.
Topics: Animals; Arginine; Cardiopulmonary Bypass; Endothelium, Vascular; Heart Arrest, Induced; Hypertension, Pulmonary; Lung; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Swine; Vascular Resistance; Vasodilation | 1996 |
Altered endothelium-dependent responses in lambs with pulmonary hypertension and increased pulmonary blood flow.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Triphosphate; Animals; Animals, Newborn; Arginine; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Pulmonary; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Phosphodiesterase Inhibitors; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Purinones; Sheep; Thromboxane A2; Vasoconstrictor Agents | 1996 |
Improvement of cardiac output and liver blood flow and reduction of pulmonary vascular resistance by intravenous infusion of L-arginine during the early reperfusion period in pig liver transplantation.
Topics: Animals; Arginine; Blood Urea Nitrogen; Cardiac Output; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Infusions, Intravenous; Liver; Liver Circulation; Liver Transplantation; Male; Nitrates; Nitrites; Oxygen; Reperfusion Injury; Swine; Vascular Resistance | 1997 |
[Protective and treated effects of L-arginine on hypoxia-induced pulmonary hypertension in rats].
Topics: Animals; Arginine; Blood Pressure; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Rats; Rats, Wistar | 1996 |
Prolonged administration of L-arginine ameliorates chronic pulmonary hypertension and pulmonary vascular remodeling in rats.
Topics: Animals; Arginine; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Injections, Intraperitoneal; Monocrotaline; Poisons; Pulmonary Artery; Pulmonary Circulation; Rats | 1997 |
Protection of perfused lung from oxidant injury by inhibitors of anion exchange.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Antiporters; Arginine; Blotting, Western; Buffers; Dipyridamole; Extracellular Space; Hypertension, Pulmonary; Immunohistochemistry; In Vitro Techniques; Lung; Nitrites; Oxidants; Oxygen; Perfusion; Pulmonary Edema; Rabbits; Superoxides | 1997 |
[Effects of L-arginine on acute hypoxic pulmonary hypertension and production of endothelin-1 in vivo and in cultured endothelial cells].
Topics: Animals; Arginine; Blood Pressure; Cells, Cultured; Dogs; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension, Pulmonary; Hypoxia; Male | 1996 |
L-arginine reduces right heart hypertrophy in hypoxia-induced pulmonary hypertension.
Topics: Animals; Arginine; Cardiomegaly; Endothelins; Heart Ventricles; Humans; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley | 1999 |
Hypoxia inhibits increased ETB receptor-mediated NO synthesis in hypertensive rat lungs.
Topics: Animals; Arginine; Biopterins; Egtazic Acid; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; In Vitro Techniques; Luminescent Measurements; Lung; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin B; Receptors, Endothelin; Time Factors | 1999 |
Pulmonary artery endothelium-dependent vasodilation is impaired in a chicken model of pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Chickens; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Ionophores; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Papaverine; Pulmonary Artery; Vasodilation; Vasodilator Agents | 1999 |
L-arginine and substance P reverse the pulmonary endothelial dysfunction caused by congenital heart surgery.
Topics: Administration, Inhalation; Arginine; Cardiopulmonary Bypass; Endothelium, Vascular; Heart Defects, Congenital; Humans; Hypertension, Pulmonary; Infant; Infusions, Intravenous; Nitric Oxide; Oxygen; Postoperative Complications; Pulmonary Circulation; Substance P; Vascular Resistance; Vasodilation; Vasodilator Agents | 1999 |
[Effect of L-arg and SNP on pulmonary arterial pressure and vascular structural changes of chronically hypoxic rats].
Topics: Animals; Antihypertensive Agents; Arginine; Blood Pressure; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; Male; Muscle, Smooth, Vascular; Nitroprusside; Pulmonary Artery; Rats; Rats, Wistar | 1997 |
Modulation of systemic hemodynamics by exogenous L-arginine in normal and bacteremic sheep.
Topics: Acidosis; Animals; Arginine; Bacteremia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Escherichia coli Infections; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Hypoxia; Injections, Intravenous; Lactic Acid; Leukopenia; Prospective Studies; Pulmonary Wedge Pressure; Respiration, Artificial; Sheep; Treatment Outcome; Vascular Resistance | 1999 |
Decreased synthesis and vasodilation to nitric oxide in piglets with hypoxia-induced pulmonary hypertension.
Topics: Animals; Animals, Newborn; Arginine; Blood Vessels; Cyclic GMP; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Circulation; Swine; Vasodilation; Vasodilator Agents | 2000 |
[Experimental study of hypoxic pulmonary hypertension induced by nitric oxide in rats].
Topics: Animals; Arginine; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Nitroarginine; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 1997 |
[A study of the effects of L-arginine in pathogenesis of hypoxic pulmonary hypertension].
Topics: Animals; Arginine; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 2000 |
[Changes of nitric oxide synthase in hypoxic pulmonary hypertension and the effect of L-arg and L-NAME on pulmonary circulation].
Topics: Animals; Arginine; Endothelium, Vascular; Female; Hypertension, Pulmonary; Hypoxia; Lung; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Circulation; Random Allocation; Rats; Rats, Wistar | 1998 |
Plasma levels of asymmetrical dimethyl-L-arginine in patients with congenital heart disease and pulmonary hypertension.
Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Enzyme Inhibitors; Heart Defects, Congenital; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; Nitric Oxide Synthase | 2001 |
[L-arginine prolonged the efficacy of inhaled nitric oxide on the inhibition of pulmonary hypertension].
Topics: Administration, Inhalation; Animals; Arginine; Blood Pressure; Drug Synergism; Female; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Pulmonary Artery; Swine; Vascular Resistance; Vasodilator Agents | 1998 |
Interrelation between nitric oxide and endothelin-1 in an experimental acute hypoxia in rats and its intervention.
Topics: Animals; Arginine; Dexamethasone; Endothelin-1; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats | 1999 |
Metabolites of the L-arginine-NO pathway in patients with left-to-right shunt.
Topics: Adolescent; Adult; Age Factors; Arginine; Arteriovenous Shunt, Surgical; Cardiac Catheterization; Case-Control Studies; Child; Child, Preschool; Cyclic GMP; Endocardial Cushion Defects; Female; Heart Septal Defects; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; Male; Nitrates; Nitric Oxide; Pulmonary Circulation | 2001 |
EDRF inhibition augments pulmonary hypertension in intact newborn lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Arginine; Blood Pressure; Cardiac Output; Heart Rate; Hypertension, Pulmonary; Hypoxia; Nitric Oxide; Nitroarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Sheep; Vascular Resistance; Vasoconstrictor Agents | 1992 |
L-Arginine, a precursor of EDRF in vitro, produces pulmonary vasodilation in lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arginine; Blood Pressure; Cardiac Output; Heart Rate; Hypertension, Pulmonary; Isomerism; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Purinones; Sheep; Vasodilation | 1991 |
Pulmonary vascular reactivity to endothelin-1 in normal and chronically pulmonary hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Calcimycin; Endothelins; Hemodynamics; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Male; Muscle Tonus; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Effects of ligustrazine on the pressure/flow relationship in isolated perfused rat lungs.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Hypertension, Pulmonary; Hypoxia; Male; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Pyrazines; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents | 1991 |
N omega-nitro-L-arginine attenuates endothelium-dependent pulmonary vasodilation in lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Binding, Competitive; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Hemodynamics; Hypertension, Pulmonary; Isoproterenol; Lung; Nitric Oxide; Nitroarginine; Nitroprusside; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Sheep; Vasodilation | 1991 |