arginine and Neoplasms

arginine has been researched along with Neoplasms in 383 studies

Research

Studies (383)

TimeframeStudies, this research(%)All Research%
pre-199070 (18.28)18.7374
1990's46 (12.01)18.2507
2000's60 (15.67)29.6817
2010's119 (31.07)24.3611
2020's88 (22.98)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Chien, HC; Colas, C; Giacomini, KM; Hall, C; Schlessinger, A; Thomas, AA; Wells, A; Wolfe, H1
Chen, Z; DiGiovanni, J; Wilder, CS1
Richard, S; Xu, J1
Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y1
Jiang, L; Qiu, L; Wang, K1
Du, H; Liu, SS; Qian, LX; Wang, F; Wang, XW; Xu, HX1
Andresen, TL; Bak, M; Christensen, E; Kempen, PJ; Kristensen, K; Larsen, JB; Münter, R; Parhamifar, L1
Ji, C; Li, Z; Liu, P; Niu, F; Qian, L; Ren, Y; Xiong, Y; Ye, Q; Yu, Y1
Bagheri, M; Behzadi, M; Eghtedardoost, M1
Akhmetshina, A; Burgering, B; Eisenberg, T; Fasching, S; Hörl, G; Jany-Luig, E; Kerbl-Knapp, J; Korbelius, M; Kratky, D; Kuentzel, KB; Macher, T; Mack, M; Madl, T; Meinitzer, A; Paar, M; Pertschy, B; Pirchheim, A; Rinner, B; Rodriguez Colman, MJ; Stelzl, U; Steyrer, E; Vujić, N; Zhang, F1
Dai, W; Gong, J; Gong, Y; He, F; Li, S; Liu, Q; Tang, F; Wang, Z; Xie, C; Yang, Z; Zhang, J1
Burke, JP; Duggan, WP; O'Connell, E; Prehn, JHM1
Belykh, DV; Berezin, DB; Karimov, DR; Kukushkina, NV; Kustov, AV; Kustova, TV; Mal'shakova, MV; Morshnev, PK; Shukhto, OV; Smirnova, NL; Zorin, VP; Zorina, TE1
Coyne, MJ; Drake, C; Kincaid, D; McCrann, DJ1
Brekker, MA; Causey, CP; Knuckley, B; Rehman, FK; Sartawi, T; Sawatzky, TM1
Han, Y; Ju, HQ; Li, B; Li, H; Li, JJ; Liao, K; Lin, JF; Lu, YX; Luo, XJ; Meng, Q; Tan, YT; Wang, ZX; Wei, C; Xu, RH; Yu, K; Zeng, ZL1
Chen, M; Chen, X; Guo, Z; Liang, R; Tian, H; Wang, Z1
Cavaretta, JP; Huang, L; Huang, T; Lee, MM; Moon, D; Rozen, EJ; Sallis, B; Shohet, JM; Sun, X; Verdejo-Torres, O; Wang, G; Wigglesworth, K; Wu, Q; Zhang, L; Zhang, XO1
Choudhary, B; Mahadeva, R; Manjunath, M; Pradhan, SS; Rao K, R; Sivaramakrishnan, V; Swaroop, S1
Chen, W; Deng, X; Hu, H; Li, J; Liu, W; Song, Q; Xing, X; Yang, W; Zhang, Y1
Ecker, AK; Guiley, KZ; Morstein, J; Shokat, KM; Zhang, Z1
Calder, PC; Douglas, C; McCullough, FS; Miller, LJ; Stanworth, SJ1
Chen, L; Chen, Y; Lin, J; Liu, X; Lu, R; Wang, M; Yin, L; Zhang, J; Zhao, Z; Zheng, Y1
deGraffenried, L; Gries, P; Harlow, B; Jolly, C; McClellan, B; Tiziani, S1
Deng, M; Wan, L; Zhang, H1
Bayarsaikhan, B; Börzsei, R; Hetényi, C; Lontay, B; Zsidó, BZ1
Chen, X; Huang, J; Huang, L; Huang, S; Lin, Q; Tang, Y; Wang, S; Xu, Y; Zhu, Q; Zou, Y1
Chen, L; Fu, S; Lin, C; Ouyang, L; Zhang, D; Zhang, J; Zheng, Q1
Hlozkova, K; Safrhansova, L; Starkova, J1
Brzozowska, E; Deshmukh, S1
Andersen, MH; Ehrnrooth, E; Holmstroem, RB; Kjeldsen, JW; Lorentzen, CL; Martinenaite, E; Mørk, SK; Pedersen, AW; Svane, IM1
Hsu, SH; Hung, WC1
Ball, LE; Delaney, JR; Gan, W; Lin, B; Liu, L; Long, DT; Yin, S1
Ding, Q; Dong, H; Gu, J; Li, Y; Liu, Y; Ma, X; Miao, Z; Yang, Y; Yin, W; Zang, J; Zhang, T; Zhao, Y; Zheng, X1
Balasundaram, A; Doss, CGP1
Deng, Z; Dong, J; Duan, J; Garrido, C; Hui, Z; Xie, T; Ye, XY1
Chai, X; Cifelli, S; Fischer, C; Gathiaka, S; Kreamer, A; Kuvelkar, R; Liaw, A; McLaren, DG; Palte, RL; Richard Miller, J; So, SS; Wen, X1
Chao, S; Li, B; Pei, Y; Pei, Z; Shen, Z1
Yalta, K; Yalta, T; Yetkin, E1
Field, GC; Pavlyk, I; Szlosarek, PW1
Chen, J; Chen, Q; Li, X; Liang, X; Sun, S; Tang, Q; Wang, Y; Wu, R; Xu, M; Yue, X; Zhang, J1
Fu, L; Liu, H; Niu, C; Wu, K1
Bouley, RA; Petreaca, RC; Rasheed, S; Yoder, RJ1
Narayanan, R; Thakker, DP1
Bartee, E; Bartee, MY; Curtsinger, HD; Dryja, P1
Assi, G; Faour, WH1
Li, B; Wang, Y; Wu, X; Wu, Y; Zheng, J1
Guo, C; Han, C; Hou, X; Wang, Z; Wu, L; Zhao, L; Zheng, X1
Chu, YD; Lai, MW; Yeh, CT1
Jin, H; Liu, S; Liu, Y; Wan, L; Zhang, H; Zhang, M1
Han, X; Xu, Y; Yao, Q; You, S1
Prasad, SK; Sindhu, R; Supreeth, M; Thanmaya, M1
Chang, C; Chen, CP; Dong, W; Jiang, T; Xu, L; Zhang, G1
Du, X; Duan, J; Gao, S; Ge, K; Ma, L; Wang, L; Zhang, J; Zhou, G1
Gautier, C; Huynh, MA; Peron, C; Pol, J1
Fang, Z; Song, C; Zhang, J1
Avelar, RA; Brautigan, DL; Bryson, B; DiFeo, A; Gingras, AC; Haider, S; Jackson, M; Leonard, D; Narla, G; O'Connor, CM; Sangodkar, J; Schlatzer, D; Taylor, SE; Tokala, E; Upadhyay, A; Wang, Z; Westermarck, J; Wiredja, D; Xu, W1
Adam, S; Bashtrykov, P; Baude, A; Dukatz, M; Emperle, M; Jeltsch, A; Kunert, S; Plass, C; Rathert, P1
Chen, X; Li, Y; Li, Z; Qi, Y; Sun, X; Wang, Y; Yang, P; Zhang, N; Zhang, S; Zhong, J1
Chen, M; Chen, X; Guo, Z; Hao, K; Lin, L; Liu, F; Sun, P; Tang, Z; Tian, H; Wang, D; Yu, H1
Bobak, YP; Fletcher, MT; Kunz-Schughart, LA; Shuvayeva, GY; Stasyk, OV; Vovk, OI1
Al-Hamashi, AA; Diaz, K; Huang, R1
Buijsman, RC; de Man, J; Friesen, J; Grobben, Y; Uitdehaag, JCM; van den Hurk, H; van Groningen, J; Willemsen-Seegers, N; Zaman, GJR1
Harada, M; Iida, Y; Kotani, H; Notsu, Y; Satoh, Y; Taniura, T1
Golab, J; Grzywa, TM; Jasinski, M; Matryba, P; Nowis, D; Rydzynska, Z; Sosnowska, A1
Bian, X; Feng, Q; Liu, X; Ma, X; Quan, C; Wang, Y; Yao, Y; Zheng, Z; Zhou, H1
Anderson, JN; Bao, Y; Bartlett, JR; Bissonnette, S; Briant, AR; Carcel, C; Chan, K; Chen, H; Chen, L; Cheng, C; Chrétien, M; Conway Fitzgerald, A; Cyr, Y; Du, Y; El-Sayed, YY; Endo, T; Faraj, M; Fujimoto, K; Girsen, A; Goto, H; Hashimoto, D; Hayasaka, K; Hayase, E; Herrmann, N; Hidaka, D; Holst, JJ; Igbinosa, I; Iijima, H; Jeandidier, N; Jeong, DY; Jeong, GT; Joubert, M; Kagawa, I; Kahata, K; Kaushik, LK; Kim, SK; Kim, SR; Kuang, Y; Laird, M; Lamantia, V; Li, P; Li, Y; Li, Z; Lindsay, SE; Liu, X; Loizon, E; Lu, Z; Lyell, DJ; Ma, J; Magnani, CJ; Mahalingam, AK; Mandal, N; Mayer, G; Michimata, R; Ngo Sock, ET; Okada, K; Onozawa, M; Opigez, V; Palanisamy, M; Parienti, JJ; Park, YR; Pavlikova, B; Peyro Saint Paul, L; Ramsahye, N; Reyes, GA; Reznik, Y; Richardson, MT; Samo, IA; Sarkar, R; Shendge, AK; Shimizu, C; Shiratori, S; Steinberg, JR; Sugita, J; Sukwong, P; Sun, X; Sunagoya, K; Sunwoo, IY; Svendsen, B; Tang, L; Tang, Z; Teshima, T; Totée, C; Turner, BE; Unno, M; Vidal, H; Wang, C; Wang, M; Wang, S; Wang, X; Wang, Z; Wassef, H; Weeks, BT; Wong Chi Man, M; Xu, C; Xu, W; Yamamoto, S; Yu, H; Zhang, WY; Zhang, X; Zhong, Y1
Annan, RS; Creasy, CL; Liu, Y; McHugh, CF; Mohammad, HP; Montes de Oca, R; Noto, PB; Piccoli, SP; Sikorski, TW; Szapacs, ME; Wagner, CD; Zappacosta, F1
Goel, PN; Greene, MI; Grover, P1
Kong, D; Leng, X; Liu, J; Sun, Z; Wang, W; Wang, X; Wang, Z1
Chung, SF; Guan, X; Leung, YC; Tam, SY; Zhang, Y1
Berent, TE; Dorschner, JM; Jatoi, A; Kumar, R; Kunz, HE; Lanza, IR; Meyer, T; Wang, X1
Chen, R; Gan, Y; Wang, Y; Ying, S1
Chang, M; Ding, B; Han, G; Hou, Z; Kheraif, AAA; Liang, S; Lin, J; Liu, S; Wang, M; Zhao, Y1
Antman, EM; Castrillon, JA; Cheng, F; Eng, C; Fang, J; Hao, T; Hill, DE; Hou, Y; Huang, J; Keri, RA; Lathia, JD; Lightstone, FC; Liu, Z; Loscalzo, J; Lu, W; Ma, J; Martin, WR; Rabadan, R; Vidal, M; Wang, R; Wang, Y; Yue, H; Zhao, J; Zhou, Y1
Abd Elmaaboud, MA; Arab, HH; Kabel, AM1
Azurmendi, PA; Bettegowda, C; DiNapoli, SR; Douglass, J; Gabelli, SB; Hsiue, EH; Hwang, MS; Kinzler, KW; Konig, MF; Li, Y; Liu, Q; Miller, MS; Mog, BJ; Murphy, MB; Papadopoulos, N; Pardoll, DM; Paul, S; Pearlman, AH; Schaefer, A; Skora, AD; Vogelstein, B; Wang, Q; Watson, E; Wright, KM; Zhou, S1
Mondal, S; Thompson, PR1
Cheng, Y; Pan, Y; Rauf, A; Song, P; Wang, Y; Wu, X; Xu, K; Yan, J; Zhang, H; Zheng, R1
Ballabio, E; Barnkob, MB; Cerundolo, V; Chen, JL; Crump, NT; Gileadi, U; Godfrey, L; Hadjinicolaou, AV; Kessler, BM; Koohy, H; Lau, IJ; McCullagh, JSO; Milne, TA; Napolitani, G; Olsen, LR; Quek, L; Salio, M; Setshedi, M; Taylor, S; Vyas, P; Walsby-Tickle, J; Xia, M; Yu, Z1
Bae, GU; Cho, Y; Hwang, JW; Kim, SN; Kim, YK1
Martí I Líndez, AA; Reith, W1
Di Tullio, F; Guccione, E; Mzoughi, S; Schwarz, M1
Amarasekera, N; Manoharan, S; Sarker, P1
Guo, JY; Lattime, EC; White, E1
Bratlie, KM; Rehman, TU1
Du, J; Hong, K; Sun, Q; Zhang, X; Zhu, Y1
Alhumaydhi, FA; Alsagaby, SA; Batiha, GE; El-Ballat, EM; El-Demerdash, FM; El-Esawi, MA; Fareed, MM; Rauf, A1
Bansal, S; Kumari, N1
Berglund, UW; Brautigam, L; Helleday, T; Kadamov, Y; Tsuber, V1
Lenihan, DJ1
Chan, GC; Fung, MKL1
Bogeski, I; Bonhenry, D; Butorac, C; Cappello, S; Ettrich, RH; Frischauf, I; Groschner, K; Hochreiter, A; Litviňuková, M; Lunz, V; Muik, M; Pammer, T; Reha, D; Romanin, C; Schindl, R; Schober, R; Stallinger, A; Svobodová, B; Tociu, L; Zayats, V1
Bennett, MK; Chen, J; Emberley, E; Gross, MI; Huang, T; Janes, JR; Li, W; MacKinnon, AL; Makkouk, A; Marguier, G; Murray, PJ; Neou, S; Pan, A; Parlati, F; Rodriguez, MLM; Steggerda, SM; Van de Velde, LA; Wang, T; Works, M; Zhang, J; Zhang, W1
Abedi-Valugerdi, M; Hassan, M; Madjidzadeh, K; Shariatpanahi, SP1
Gu, J; Gu, Y; Liang, S; Wang, Q; Wu, L; Xu, H; Yin, L; Zhang, H; Zhao, C1
Jahani, M; Mansouri, K; Noroznezhad, F1
Cau, L; Méchin, MC; Simon, M1
Carvalho, SM; Cunha, ADS; Leite, MF; Lobato, ZIP; Mansur, AAP; Mansur, HS1
Erez, A; Keshet, R1
Dhankhar, R; Gulati, P; Kapoor, RK; Kumar, S1
Cao, X; Gao, YN; Ke, AQ; Li, ZF; Liu, AD; Liu, JY; Luo, DN; Xu, H; Yu, YQ1
Etrych, T; Fang, J; Imamura, T; Islam, W; Maeda, H; Subr, V; Ulbrich, K1
Hardy, JA; MacPherson, DJ; Mills, CL; Ondrechen, MJ1
Bosenberg, MW; Guo, JY; Hu, ZS; Jiang, C; Lattime, E; Lu, W; Maganti, A; Mehnert, JM; Poillet-Perez, L; Rabinowitz, JD; Sharp, DW; Su, X; White, E; Xie, X; Yang, Y; Zhan, L; Zheng, H1
Classen, CF; Fiedler, T; Junghanss, C; Kreikemeyer, B; Maletzki, C; Riess, C; Shokraie, F1
Berenjian, A; Ghasemi, Y; Morowvat, MH; Negahdaripour, M; Nezafat, N; Rahbar, MR; Zarei, M1
Danielak, A; Kruszewski, WJ; Szefel, J1
Harjes, U1
Cao, B; Hu, X; Ji, Z; Luo, W; Wang, W; Wang, Z; Xing, D; Zhai, S; Zhang, D; Zhang, Y1
Beal, FLR; Beal, JR; Beal, PR; Carvalho-Neves, N; Franco, OL; Silva, ON1
Bulock, CR; Chabes, A; Kane, DP; Moore, EA; Sharma, S; Shcherbakova, PV; Xing, X1
Perera, RM; Venida, A1
Bian, Y; Hu, Y; Ishimwe, N; Jin, P; Lin, J; Liu, L; Liu, Y; Qian, J; Ren, L; Sha, R; Wen, LP; Yin, S; Zhang, W; Zhang, Y1
Bogaerts, A; Ghasemitarei, M; Razzokov, J; Shokri, B; Yusupov, M1
Chen, X; Guo, T; Hu, Y; Li, Y; Li, Z; Liu, Y; Qiu, Y; Song, J; Wang, H; Yang, H1
Chu, CC; Ji, Y; Li, J; Shan, S; Zhao, J1
Patil, S; Sarode, GS; Sarode, SC; Sharma, NK1
Chang, SF; Godec, A; Hawkins, WG; Hirbe, AC; Prudner, BC; Rathore, R; Robinson, AM; Van Tine, BA1
Chakrabandhu, S; Chitapanarux, I; Chitapanarux, T; Chottaweesak, P; Jiratrachu, R; Pisprasert, V; Rasio, W; Sripan, P; Traisathit, P1
Davies, CC; Jarrold, J1
Hartley, AV; Jin, J; Lu, T; Martin, M1
Epifano, F; Felaco, M; Ferrone, A; Fiorito, S; Franceschelli, S; Gatta, DMP; Genovese, S; Grilli, A; Patruno, A; Pesce, M; Quiles, JL; Speranza, L; Taddeo, VA1
Ke, C; Liu, P; Wang, X; Xu, S; Zou, S1
Guccione, E; Richard, S1
Corbo, C; Orrù, S; Salvatore, F1
Bailey, TL; O'Connor, TR; Richard, S; Thandapani, P1
Cairns, RA; Mak, TW1
Hao, L; Song-Tao, Q; Xiao-Feng, H; Ye, S; Yi, L; Yun-Tao, L1
Fujii, C; Fujino, M; Fukunaga, M; Hachino, Y; Hamaguchi, Y; Imamura, H; Iseki, C; Ishizaka, T; Kamigaki, S; Kawabata, R; Kawase, T; Kimura, Y; Yamamoto, E1
VRAT, V1
Clegg, JM; Fay, MM; Powers, MA; Uchida, KA; Ullman, KS1
Campos, OA; Carey, MF; Kurdistani, SK; Macadangdang, BR; Oberai, A; Sheng, F; Spektor, T; Vogelauer, M1
Adamkiewicz-Drozynska, E; Stachowicz-Stencel, T; Synakiewicz, A1
Eli, M; Kong, B; Mamtimin, B; Turahun, A; Upur, H1
Alves, ID; Jobin, ML1
Boretsky, YR; Gonchar, MV; Sibirny, AA; Stasyk, OV1
Feun, LG; Kuo, MT; Savaraj, N2
Gudmann, NS; Hansen, NU; Jensen, AC; Karsdal, MA; Siebuhr, AS1
Krebs, JE; Shechter, D; Stopa, N1
Akande, T; Bomalaski, JS; Diaz, M; Dutia, MP; Gandara, DR; Gong, IY; Kelly, K; Lara, PN; Li, T; Mahaffey, N; Pan, CX; Semrad, T; Thomson, JA; Tomlinson, BK1
Didelija, IC; Marini, JC1
Choi, BY; Keum, YS1
Huang, J; Qiu, F; Sui, M1
Martindale, RG; Moore, FA; Rosenthal, MD; Vanzant, EL1
Queiroz, JA; Sousa, Â; Sousa, F1
Chang, JT; Davies, MA; Feun, LG; Kuo, MT; Liu, H; Long, Y; Park, JR; Rodriguez-Canales, J; Savaraj, N; Tsai, WB; Wistuba, II1
Bordeleau, F; Califano, JP; LaValley, DJ; Mason, BN; Negrón Abril, YL; Reinhart-King, CA; Shin, SJ; Weiss, RS1
Georgakis, MK; Latsios, G; Oikonomou, E; Papageorgiou, N; Papaioannou, S; Siasos, G; Tousoulis, D; Zaromitidou, M1
Cao, W; Gao, G; Gu, Y; Li, S; Liu, M; Shan, L; Wu, C; Xu, L; Zhao, L1
Li, G; Liu, F; Yang, Y; Zhang, L; Zhou, Y1
Deng, X; Dohmae, N; Hamamoto, R; Nakakido, M; Nakamura, Y; Piao, L; Suzuki, T; Von Keudell, G; Yoshioka, Y1
Bachman, M; Balasubramanian, S; Chin, JW; Elsässer, SJ; Mahesh, M; Walker, OS1
Janakiram, NB; Kumar, G; Madka, V; Mohammed, A; Rao, CV1
Choi, M; Gujrati, V; Jon, S; Kang, S; Kim, H; Kim, JI; Lee, J; Lee, Y; Saw, PE1
De Santo, C; Fultang, L; Mussai, F; Vardon, A1
Chandana, T; Venkatesh, YP1
Ashcroft, M; Burrows, N; Cane, G; Frezza, C; Gaude, E; Howat, WJ; Maxwell, PH; Pedley, RB; Robson, M; Szlosarek, PW1
Botelho, MG; Lau, SK; Lo, RC; Teng, JL; Woo, PC; Xiong, L1
Babykutty, S; Banerjee, UC; Bhaumik, J; Fukumura, D; Patil, MD1
Arachchillage, DR; Baglin, T; Besser, M; Maclean, R; van Veen, JJ1
Amin, ML; Kim, D; Kim, S1
Chen, H; Gupta, V; Lorton, B; Shechter, D1
Suematsu, M; Yamamoto, T1
Corbo, L; Le Romancer, M; Poulard, C1
Chang, JT; Chen, HH; Estecio, M; Feun, LG; Kuo, MT; Long, Y; Savaraj, N; Tsai, WB; Wangpaichitr, M1
Albaugh, VL; Barbul, A; Pinzon-Guzman, C1
Peng, C; Wong, CC1
Kuroda, S; Yugi, K1
Chen, J; He, G; Huang, Z; Yan, Q; Yi, X; Yin, Y; Zeng, T; Zhang, L; Zhang, Y1
Fujita, T; Furuhata, M; Hattori, Y; Kawakami, H; Maitani, Y; Toma, K1
Aletta, JM; Hu, JC1
BACH, SJ; LASNITZKI, I2
Klose, RJ; Ng, SS; Oppermann, U; Yue, WW1
Bera, S; Ray, M; Ray, S; Wallimann, T1
Bazer, FW; Carey Satterfield, M; Davis, TA; Kim, SW; Li, P; Marc Rhoads, J; Smith, SB; Spencer, TE; Wu, G; Yin, Y1
Bellone, M; Capuano, G; Freschi, M; Grioni, M; Rigamonti, N1
Cho, EC; Durant, ST; La Thangue, NB1
Fujisaki, Y; Horii, Y; Nagai, K; Shen, J1
Boelens, PG; De Bandt, JP; Dejong, CH; Deutz, NE; Ligthart-Melis, GC; van de Poll, MC; van den Tol, MP; van Leeuwen, PA; van Schaik, C; Vermeulen, MA1
Clerkin, K; Liang, JF; Shah, K; Tu, Z; Volk, M1
Glenfield, K; Jeyanthan, K; Mitchell, TR; Zhu, XD1
Gunduz, M; Mita, Y; Naomoto, Y; Ouchida, M; Sakai, A; Shimizu, K; Tanabe, S; Toyooka, S; Yamamoto, H; Yasuda, Y1
Hauser, AT; Heinke, R; Jung, M; Sippl, W; Spannhoff, A1
Munder, M1
Kim, PH; Kim, SW; Kim, TI; Yockman, JW; Yun, CO1
Cavaillès, V; Corbo, L; Jalaguier, S; Le Romancer, M; Sentis, S; Teyssier, C1
Choi, YB; Kim, NY; Kim, SW; Park, SH; Shin, S; Yang, JM1
Crook, T; Delage, B; Fennell, DA; Lemoine, NR; McNeish, I; Nicholson, L; Szlosarek, PW1
Guo, K; Hu, H; Li, J; Ma, Q; Sha, H; Wang, Z; Zhang, D; Zhang, M1
IRONS, WG1
Field, HI; Hamamoto, R; Hayami, S; Kelly, JD; Maehara, Y; Nakamura, Y; Neal, DE; Ponder, BA; Toyokawa, G; Tsunoda, T; Unoki, M; Yoshimatsu, M1
Reitman, ZJ; Yan, H1
Chen, BG; Liu, Z; Lu, Y; Mao, HM; Wei, W; Xiong, WJ1
Chen, RL; Huang, Y; Lee, HJ; Li, JF1
Bobak, YP; Kurlishchuk, YV; Sibirny, AA; Stasyk, OV; Vynnytska, BO1
Bobak, YP; Kurlishchuk, YV; Mayevska, OM; Stasyk, OV; Vynnytska, BO1
GREENSTEIN, JP; LEUTHARDT, FM1
Aletta, JM; Beghelli, S; Della Peruta, M; Mafficini, A; Mojica, WD; Mombello, A; Moratti, E; Scarpa, A; Sorio, C; Vezzalini, M1
Li, L; Li, N; Liu, Y; Ni, Y; Schwaneberg, U; Sun, Z; Zhu, L1
Adoue, V; Arnaud, J; Coudane, F; Méchin, MC; Nachat, R; Serre, G; Simon, M1
Aldawsari, H; Blatchford, DR; Dufès, C; Edrada-Ebel, R; Raj, BS; Tate, RJ; Tetley, L1
Lee, YH; Stallcup, MR1
Chang, YC; Liang, YF; Shen, LJ; Wei, MF; Wu, FL; Yo, HH1
Behrens, A; Davis, H; Lewis, A; Spencer-Dene, B; Stamp, G; Tateossian, H; Tomlinson, I1
Morassutti, I; Paccagnella, A; Rosti, G1
Aldawsari, H; Blatchford, DR; Dufès, C; Edrada-Ebel, R; Tate, RJ; Tetley, L1
Dwarakanath, BS; Ganguli, M; Jiang, Y; Kalra, N; Khanduri, R; Langel, U; Mann, A; Naik, R; Shukla, V; Singh, AK; Thakur, G1
Daly, JM; Jayarajan, S1
Ma, DX; Qi, XR; Shi, NQ1
Raines, RT; Sundlass, NK1
Chantranupong, L; Georgiou, G; Gonzalez, C; O'Neal, J; Rani, M; Stone, E; VanDenBerg, C1
Guan, W; Hu, Z; Huang, Y; Sun, S; Yao, Y; Zhang, C1
Cao, F; Huang, A; Li, H; Li, S; Ping, Q; Su, Z; Sun, M; Xiao, Y; Zhang, C1
La Thangue, NB; Moehlenbrink, J1
Buijs, N; Houdijk, AP; Luttikhold, J; van Leeuwen, PA1
Ochoa, AC; Raber, P; Rodríguez, PC1
Edwards, RP; Kalinski, P; Moysich, K; Obermajer, N; Odunsi, K; Wong, JL1
Bedford, MT; Yang, Y1
Kitamura, H; Masuko, K; Nakano, K; Narita, Y; Nishimura, T; Sumida, K; Terada, S; Wakita, D1
Buchegger, F; Dupertuis, YM; Pichard, C; Raguso, CA1
Dupertuis, YM; Genton, L; Karsegard, V; Maisonneuve, N; Pichard, C; Uldry, C1
Della Pietra, AC; Dumont, P; George, DL; Leu, JI; Murphy, M1
Kim, HH; Lee, WS; Shin, S; Yang, JM1
Fernández, A1
KRUSE, PF; McCOY, TA1
FLIPPIN, RS; MICKELSON, MN1
JOHNSTONE, RM1
PRAVDINA, KI1
BUSCH, H; DAVIS, JR; HONIG, GR1
BUSCH, H; STARBUCK, WC1
FUJII, M; HANO, S; ISHII, H; IWATA, S; KAGEYAMA, T; KURISU, T; TSUTSUMI, T; WADA, M; WAKABAYASHI, A1
GENTY, N; MELONI, GA; VENDRELY, R1
BECKMAN, D; BOLINE, J; VANPILSUM, JF; WARHOL, RM1
CHRISTENSEN, HN1
THOMPSON, CB1
ARMSTRONG, D; HAYFLICK, L; HENLE, G; SOMERSON, NL1
Bomalaski, JS; Clark, MA; Curley, SA; Dillon, BJ; Ensor, CM; Holtsberg, FW; Prieto, VG1
He, D; Huang, H; Lin, Q; Yang, H1
Wheatley, DN2
Czeczot, H; Scibior, D1
Choudry, HA; Epler, MJ; Karinch, A; Lin, C; Meng, Q; Pan, M; Souba, W1
Lind, DS1
Krause, E; Lödige, I; Meissner, T; Vinkemeier, U1
Dejong, CH; Deutz, NE; Fearon, KC; Luiking, YC; Vissers, YL; von Meyenfeldt, MF1
Okada, N1
Barbi, C; Bonafé, M; Franceschi, C; Gravina, S; Mondello, C; Monti, D; Rossi, M; Salvioli, S; Storci, G; Tiberi, L; Tocco, F; Trapassi, C1
Campbell, E; Kilfeather, R; Stitt, A; Wheatley, DN1
Beloussow, K; Shen, LJ; Shen, WC1
Roth, E; Wessner, B1
Baralle, D; Bonthron, DT; Charlton, R; Cole, TR; De Vos, M; Glaser, AW; Hayward, BE; Maher, ER; Mann, JR; McKeown, CM; Picton, S; Rankin, J; Sheridan, E; Taylor, GR; Yates, JR1
Prives, C; Zupnick, A1
Feun, L; Savaraj, N1
Graboń, W1
Ochoa, AC; Quiceno, DG; Rodriguez, PC1
Lavasanifar, A; Mahmud, A; Uludağ, H; Xiong, XB1
Hamajima, N; Hatooka, S; Hishida, A; Iwata, H; Kagami, Y; Kato, T; Matsuo, K; Mitsudomi, T; Naito, M; Ogura, M; Shinoda, M; Suyama, M; Tajima, K; Tamakoshi, A; Tanaka, D; Yamamoto, K; Yamamura, Y1
Ishida, T; Kashima, T; Makino, K; Soemantri, A1
Pal, S; Sif, S1
Gabrilovich, DI; Nagaraj, S1
Bronte, V; Dolcetti, L; Mantelli, B; Marigo, I; Peranzoni, E; Sonda, N; Taschin, E; Ugel, S; Zanovello, P1
Marx, J1
Berk, L; Hug, E; James, J; Kachnic, L; Mahadevan, A; Samuels, M; Schwartz, A1
Ochoa, AC; Rodríguez, PC1
Kapoor, S1
Brown, RR1
Cerutti, I; Chany, C1
Saito, H; Saito, S1
Cho-Chung, YS1
Bannai, K; Ishigaki, S; Ishii, B; Kogawa, K; Kohgo, Y; Koshida, Y; Kumai, R; Mogi, Y; Niitsu, Y; Urushizaki, I1
Holcenberg, JS1
Daly, JM; Hill, AD1
Garlick, PJ; McNurlan, MA1
Brittenden, J; Eremin, O; Heys, SD; Park, KG; Ross, J1
Brittenden, J; Eremin, O; Heys, SD1
Park, KG1
Bonaïti-Pellié, C; Brugières, L; Chompret, A; Flamant, F; Gardes, M; Lemerle, J; Martin, A; Meresse, V; Moutou, C; Poisson, N1
Gardiner, KR; Kirk, SJ; Neilly, PJ; Rowlands, BJ1
Eremin, O; Gough, DB; Heys, SD; Khan, L1
Carlberg, M; Johansson, KU1
Das, UN1
Griffith, OW; Kilbourn, RG2
Bunnak, A; Chockvivatanavanit, S; Chuntrasakul, C; Leowattana, W; Sarasombath, S; Siltharm, S; Sittapairochana, C1
Barber, MD; Delmore, G; Fearon, KC; Loprinzi, CL1
Masek, K; Zidek, Z1
Keshava, C; McCanlies, EC; Sharp, DS; Sun, Y; Weston, A1
Lima, LA; Novaes, MR1
Field, CJ; Johnson, I; Pratt, VC1
Lamb, J; Scott, L; Smith, S; Wheatley, DN1
Furuuchi, K; Hirai, A; Iggo, RD; Kaneda, M; Matsumoto, J; Mitsumoto, Y; Moriuchi, T; Tada, M; Takahashi, M1
Pham, HT; Ruediger, R; Walter, G1
Doi, H; Komatsu, H; Nishihira, T; Satomi, S1
Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H1
Dechelotte, P; Nitenberg, G1
Abumrad, NN; Barber, A; D'Olimpio, JT; Hourihane, A; May, PE1
Campbell, E; Wheatley, DN1
Caviezel, F; Girardi, AM; Murari, M; Poli, M; Pozza, G1
Ehrmeyer, SL; Joiner, BL; Kahan, L; Larson, FC; Metzenberg, RL1
Berry, DH; Dickinson, L; Dickinson, WP; Elders, MJ; Fiser, RH; Irvin, M; Schedewie, H1
Brajerski, W1
Carnegie, PR; Fellows, FC; Symington, GR1
Badowski, A; Orłowski, T; Witkowski, W1
Kobayashi, Y; Watanabe, N; Yoshikawa, T1
Egyud, LG; Lipinski, B1
Mülsch, A1
Matsumoto, H; Mori, S1
Hung, MC; Klostergaard, J; Leroux, ME1
Cacciatore, L; Fabris, N; Lingetti, M; Mocchegiani, E; Talarico, M1
Keist, R; Keller, R; Leist, TP; van der Meide, PH; Wechsler, A1
Alexander, JW; Peck, MD1
Blackburn, GL; Lowell, JA; Parnes, HL1
Merimee, TJ1
Bowser-Finn, RA; Kahan, L; Larson, FC; Traver, MI1
Kiyotaki, C1
Klostergaard, J; Leroux, ME1
Gabrielli, F; Tsugita, A1
Csiba, A; Rusznák, I; Trézl, L1
Balabanova, G; Becker, Y; Kotler, M; Weinberg, E1
Landon, J; Ratcliffe, JG; Rees, LH; Scott, AP1
Farbiszewski, R; Rzeczycki, W1
Farbiszewski, R; Glowinski, S; Rzeczycki, W; Worowski, K1
Asano, H; Kojima, R; Shimada, K1
Inoue, M; Nagata, Y1
Saito, T; Yoshida, S1
Farbiszewski, R; Rzeczycki, W; Worowski, K2
Kellen, JA; Lustig, V1
Abe, K; Kumagai, N; Mouri, T; Seki, T; Yoshinaga, K1
Freed, JJ; Schatz, SA1
Butschak, G; Graffi, A; Schneider, EJ1
Duan, L; He, S; Li, Y; Yang, H; Zhang, R1
Bicaku, E; Daud, AI; Marchion, DC; Munster, PN; Sullivan, DM; Turner, JG1
Marik, PE; Vahid, B1
Pawlicki, M; Zuchowska-Vogelgesang, B1
Płuzańska, A; Robak, T1
Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ1
Campbell, ED; Carter, WH; Stablein, DM; Wampler, GL1
Fuerst, ML1
Reich, SD1
Issell, BF1
Macbeth, FR1
Curry, ME; Issell, BF; Tihon, C1
Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA1
Schulz, JJ; Speckhart, VJ; Spremulli, E; Wampler, GL1
Felix, CA; Hosler, MR; Lange, BJ; Masterson, M; Wilson, AE; Winick, NJ1
Muggia, FM1
Joel, SP; Slevin, ML1
Crist, WM; Pratt, CB; Pui, CH; Rivera, GK; Santana, VM1
Evans, WE; McLeod, HL1
Kohno, K; Kuwano, M; Matsuo, K; Sato, S; Tanimura, H; Uchiumi, T; Yamada, Y1
Abe, T; Hisano, T; Kohno, K; Koike, K; Kubo, T; Kuwano, M; Wada, M1
Furukawa, M; Harada, T; Kuwano, M; Tanaka, T1
Hande, KR1
de Jong, RS; de Vries, EG; Groen, HJ; Höppener, FJ; Mulder, NH; Sleijfer, DT; Uges, DR; van der Graaf, WT; Willemse, PH1
Carter, SK; Slavik, M1
Adamson, RH; Mead, JA; Sieber, SM1
Carter, SK; Muggia, FM; Rozencweig, M; Slavik, M1
Sullivan, MP; Sutow, WW1
Bleyer, WA; Chard, RL; Hammond, D; Krivit, W1
Crooke, ST; Gutierrez, ML1
Allen, LM; Creaven, PJ1
Amiel, JL; Mathé, G; Misset, JL; Oldham, R; Pouillart, P; Schwarzenberg, L; Weiner, R1
Anderson, GR; Beerman, TA; Russo, CA; Spina, AM; Stoler, DL1
Weiss, RB1
Holthuis, JJ; Kok, TC; Post, MH; Splinter, TA1
Kok, TC; Smit, EF; Splinter, TA1
Kelley, SL; Muggia, FM1
Crist, WM; Crom, WR; Evans, WE; Groom, S; McLeod, HL; Relling, MV; Rivera, GK; Rodman, JH; Silverstein, K1
Chang, EH; Cunningham, JM; Francis, GE; Holland, MJ; Pirollo, KF1
D'Incalci, M; Garattini, S1
Holden, JA; Rolfson, DH; Wittwer, CT1
Bugat, R; Canal, P; Chatelut, E; Chevreau, C; De Forni, M; Houin, G1
McVie, G; Muggia, FM1
de Vries, EG; Mulder, NH; Postmus, PE; Sleijfer, DT; Vriesendorp, R; Willemse, PH1

Reviews

143 review(s) available for arginine and Neoplasms

ArticleYear
Pharmacologic approaches to amino acid depletion for cancer therapy.
    Molecular carcinogenesis, 2022, Volume: 61, Issue:2

    Topics: Amino Acids; Arginine; Glutamine; Humans; Neoplasms; Oxidation-Reduction

2022
Cellular pathways influenced by protein arginine methylation: Implications for cancer.
    Molecular cell, 2021, 11-04, Volume: 81, Issue:21

    Topics: Alternative Splicing; Animals; Arginine; B7-H1 Antigen; Cell Communication; Cell Line, Tumor; CRISPR-Cas Systems; DNA Damage; DNA Repair; Enzyme Inhibitors; Epigenesis, Genetic; Histones; Humans; Immune System; Immunotherapy; Methylation; Mice; Mice, Knockout; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; RNA Splicing; RNA, Messenger; Signal Transduction

2021
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
    International journal of molecular sciences, 2021, Oct-22, Volume: 22, Issue:21

    Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction

2021
Arginase: An emerging and promising therapeutic target for cancer treatment.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 149

    Topics: Animals; Arginase; Arginine; Mammals; Neoplasms; Tumor Microenvironment; Urea

2022
Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Arginine; Humans; Immunologic Factors; Immunotherapy; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases; Quality of Life

2022
Serine-Arginine Protein Kinase 1 (SRPK1): a systematic review of its multimodal role in oncogenesis.
    Molecular and cellular biochemistry, 2022, Volume: 477, Issue:10

    Topics: Arginine; Arginine Kinase; Carcinogenesis; Cell Transformation, Neoplastic; Humans; Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; RNA Splicing Factors; Serine; Transforming Growth Factor beta

2022
Impact of enteral immunonutrition on infectious complications and immune and inflammatory markers in cancer patients undergoing chemotherapy: A systematic review of randomised controlled trials.
    Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:10

    Topics: Adult; Arginine; Biomarkers; Fatty Acids, Omega-3; Glutamine; Humans; Malnutrition; Neoplasms; Nucleotides; Randomized Controlled Trials as Topic; Tumor Necrosis Factor-alpha; Vitamin A; Vitamins

2022
SR Splicing Factors Promote Cancer via Multiple Regulatory Mechanisms.
    Genes, 2022, 09-16, Volume: 13, Issue:9

    Topics: Arginine; Humans; Neoplasms; RNA; RNA Splicing Factors; RNA-Binding Proteins; Serine; Serine-Arginine Splicing Factors

2022
Medicinal chemistry strategies targeting PRMT5 for cancer therapy.
    European journal of medicinal chemistry, 2022, Dec-15, Volume: 244

    Topics: Arginine; Chemistry, Pharmaceutical; Enzyme Inhibitors; Humans; Molecular Targeted Therapy; Neoplasms; Protein-Arginine N-Methyltransferases

2022
Targeting amino acid metabolism in cancer.
    International review of cell and molecular biology, 2022, Volume: 373

    Topics: Amino Acids; Arginine; Asparagine; Cysteine; Humans; Methionine; Neoplasms

2022
Integrin Alpha v Beta 6 (αvβ6) and Its Implications in Cancer Treatment.
    International journal of molecular sciences, 2022, Oct-15, Volume: 23, Issue:20

    Topics: Antigens, Neoplasm; Arginine; Aspartic Acid; Glycine; Humans; Integrin alphaV; Integrins; Neoplasms; Oligopeptides; Transforming Growth Factor beta

2022
Protein arginine methyltransferase 3: A crucial regulator in metabolic reprogramming and gene expression in cancers.
    Cancer letters, 2023, 02-01, Volume: 554

    Topics: Arginine; Gene Expression; Humans; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases

2023
An updated patent review of protein arginine N-methyltransferase inhibitors (2019-2022).
    Expert opinion on therapeutic patents, 2022, Volume: 32, Issue:12

    Topics: Arginine; Enzyme Inhibitors; Humans; Neoplasms; Patents as Topic; Protein-Arginine N-Methyltransferases

2022
Bench-to-Bedside Studies of Arginine Deprivation in Cancer.
    Molecules (Basel, Switzerland), 2023, Feb-24, Volume: 28, Issue:5

    Topics: Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Humans; Hydrolases; Neoplasms; Polyethylene Glycols

2023
Research progress on PRMTs involved in epigenetic modification and tumour signalling pathway regulation (Review).
    International journal of oncology, 2023, Volume: 62, Issue:5

    Topics: Arginine; Carcinogenesis; Epigenesis, Genetic; Humans; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Signal Transduction; Tumor Microenvironment

2023
Arginine deiminase produced by lactic acid bacteria as a potent anti-cancer drug.
    Medical oncology (Northwood, London, England), 2023, May-12, Volume: 40, Issue:6

    Topics: Antineoplastic Agents; Arginine; Bacteria; Humans; Hydrolases; Lactobacillales; Neoplasms

2023
Arginine deprivation as a treatment approach targeting cancer cell metabolism and survival: A review of the literature.
    European journal of pharmacology, 2023, Aug-15, Volume: 953

    Topics: Amino Acids; Apoptosis; Arginine; Cell Death; Cell Line, Tumor; Humans; Neoplasms

2023
Targeting Arginine Methyltransferase PRMT5 for Cancer Therapy: Updated Progress and Novel Strategies.
    Journal of medicinal chemistry, 2023, 07-13, Volume: 66, Issue:13

    Topics: Arginine; Histones; Humans; Intracellular Signaling Peptides and Proteins; Neoplasms; Protein-Arginine N-Methyltransferases

2023
Unlocking the Potential of Arginine Deprivation Therapy: Recent Breakthroughs and Promising Future for Cancer Treatment.
    International journal of molecular sciences, 2023, Jun-26, Volume: 24, Issue:13

    Topics: Arginine; Argininosuccinate Synthase; Cell Death; Cell Line, Tumor; Humans; Hydrolases; Neoplasms; Polyethylene Glycols

2023
Research progress on the role of cationic amino acid transporter (CAT) family members in malignant tumors and immune microenvironment.
    Amino acids, 2023, Volume: 55, Issue:10

    Topics: Amino Acid Transport Systems, Basic; Amino Acids; Animals; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Humans; Mammals; Neoplasms; Tumor Microenvironment

2023
Shuttle between arginine and lysine: influence on cancer immunonutrition.
    Amino acids, 2023, Volume: 55, Issue:11

    Topics: Amino Acids; Arginine; Diet; Immunonutrition Diet; Lysine; Neoplasms

2023
Non-Histone Arginine Methylation by Protein Arginine Methyltransferases.
    Current protein & peptide science, 2020, Volume: 21, Issue:7

    Topics: Antineoplastic Agents; Arginine; Cardiovascular Diseases; Enzyme Inhibitors; Epigenesis, Genetic; Histones; Humans; Metabolic Diseases; Methylation; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; RNA Splicing; Signal Transduction; Transcription Factors

2020
Myeloid Cell-Derived Arginase in Cancer Immune Response.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Animals; Antineoplastic Agents; Arginase; Arginine; Clinical Trials as Topic; Humans; Macrophages; Mice; Myeloid Cells; Myeloid Progenitor Cells; Neoplasms

2020
PRMT5 and Tip60 Modify FOXP3 Function in Tumor Immunity.
    Critical reviews in immunology, 2020, Volume: 40, Issue:4

    Topics: Arginine; Epigenesis, Genetic; Forkhead Transcription Factors; Humans; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases

2020
Arginine deprivation as a strategy for cancer therapy: An insight into drug design and drug combination.
    Cancer letters, 2021, 04-01, Volume: 502

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arginase; Arginine; Clinical Trials as Topic; Drug Design; Humans; Hydrolases; Neoplasms

2021
The roles of PAD2- and PAD4-mediated protein citrullination catalysis in cancers.
    International journal of cancer, 2021, 01-15, Volume: 148, Issue:2

    Topics: Animals; Arginine; Citrulline; Humans; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4

2021
Chemical biology of protein citrullination by the protein A arginine deiminases.
    Current opinion in chemical biology, 2021, Volume: 63

    Topics: Animals; Arginine; Autoimmune Diseases; Catalysis; Citrullination; Citrulline; Epigenesis, Genetic; Humans; Neoplasms; Neurodegenerative Diseases; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteins

2021
Protein arginine methyltransferases: promising targets for cancer therapy.
    Experimental & molecular medicine, 2021, Volume: 53, Issue:5

    Topics: Antineoplastic Agents; Arginine; Biomarkers, Tumor; Cell Cycle; Disease Management; Disease Susceptibility; DNA Damage; Drug Development; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Methylation; Molecular Targeted Therapy; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases

2021
Arginine-dependent immune responses.
    Cellular and molecular life sciences : CMLS, 2021, Volume: 78, Issue:13

    Topics: Animals; Arginine; Communicable Diseases; Humans; Immunity; Neoplasms

2021
Cancer synthetic vulnerabilities to protein arginine methyltransferase inhibitors.
    Current opinion in pharmacology, 2021, Volume: 59

    Topics: Arginine; Humans; Methylation; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases

2021
Autophagy Regulates Stress Responses, Metabolism, and Anticancer Immunity.
    Trends in cancer, 2021, Volume: 7, Issue:8

    Topics: Adaptive Immunity; Alanine; Animals; Antineoplastic Agents; Arginine; Autophagy; Drug Resistance, Neoplasm; Humans; Lymphocyte Activation; Metabolic Networks and Pathways; Mice; Models, Animal; Neoplasms; Stress, Physiological; T-Lymphocytes; Tumor Escape

2021
Arginine depriving enzymes: applications as emerging therapeutics in cancer treatment.
    Cancer chemotherapy and pharmacology, 2021, Volume: 88, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Arginine; Autophagy; Cell Proliferation; Enzymes; Humans; Neoplasms; Oxidative Stress

2021
Drug-induced amino acid deprivation as strategy for cancer therapy.
    Journal of hematology & oncology, 2017, 07-27, Volume: 10, Issue:1

    Topics: Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparaginase; Glutamine; Humans; Neoplasms

2017
Arginine: Challenges and opportunities of this two-faced molecule in cancer therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: Animals; Arginine; Carcinogenesis; Humans; Immunity; Metabolome; Models, Biological; Neoplasms

2018
Peptidylarginine deiminases and deiminated proteins at the epidermal barrier.
    Experimental dermatology, 2018, Volume: 27, Issue:8

    Topics: Animals; Arginine; Arthritis, Rheumatoid; Calcium; Citrulline; Epidermal Cells; Epidermis; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrolases; Inflammation; Mice; Neoplasms; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminases

2018
Arginine and the metabolic regulation of nitric oxide synthesis in cancer.
    Disease models & mechanisms, 2018, 08-06, Volume: 11, Issue:8

    Topics: Animals; Antineoplastic Agents; Arginine; Humans; Models, Biological; Neoplasms; Nitric Oxide

2018
Arginine-lowering enzymes against cancer: a technocommercial analysis through patent landscape.
    Expert opinion on therapeutic patents, 2018, Volume: 28, Issue:8

    Topics: Animals; Antineoplastic Agents; Arginine; Drug Design; Humans; Hydrolases; Neoplasms; Patents as Topic; Polyethylene Glycols

2018
Arginine-Depleting Enzymes - An Increasingly Recognized Treatment Strategy for Therapy-Refractory Malignancies.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 51, Issue:2

    Topics: Arginase; Arginine; Humans; Hydrolases; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Tumor Microenvironment

2018
Arginine Deiminase: Current Understanding and Applications.
    Recent patents on biotechnology, 2019, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Arginine; Clinical Trials as Topic; Cloning, Molecular; Escherichia coli; Gene Expression; Humans; Hydrolases; Models, Molecular; Mycoplasma; Mycoplasma penetrans; Neoplasms; Patents as Topic; Protein Engineering; Protein Structure, Secondary; Pseudomonas aeruginosa; Recombinant Proteins

2019
Metabolic pathways of L-arginine and therapeutic consequences in tumors.
    Advances in medical sciences, 2019, Volume: 64, Issue:1

    Topics: Animals; Arginine; Humans; Metabolic Networks and Pathways; Myeloid-Derived Suppressor Cells; Neoplasms

2019
Perspectives on the Therapeutic Benefits of Arginine Supplementation in Cancer Treatment.
    Endocrine, metabolic & immune disorders drug targets, 2019, Volume: 19, Issue:7

    Topics: Animals; Antineoplastic Agents; Arginine; Dietary Supplements; Humans; Neoplasms; Treatment Outcome

2019
PRMTs and Arginine Methylation: Cancer's Best-Kept Secret?
    Trends in molecular medicine, 2019, Volume: 25, Issue:11

    Topics: Animals; Antineoplastic Agents; Arginine; DNA Damage; Drug Resistance; Epigenomics; Histones; Humans; Immunotherapy; Methylation; Mice; Molecular Targeted Therapy; Neoplasms; Protein Processing, Post-Translational; Protein Splicing; Protein-Arginine N-Methyltransferases; RNA Splicing; Stem Cells

2019
PRMTs and miRNAs: functional cooperation in cancer and beyond.
    Cell cycle (Georgetown, Tex.), 2019, Volume: 18, Issue:15

    Topics: 3' Untranslated Regions; Arginine; Cardiovascular Diseases; Epigenesis, Genetic; Histones; Humans; Inflammation; Methylation; MicroRNAs; Neoplasms; Neurodegenerative Diseases; Peptide Chain Initiation, Translational; Protein Binding; Protein-Arginine N-Methyltransferases

2019
Arginine metabolism and deprivation in cancer therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 118

    Topics: Animals; Antineoplastic Agents; Arginine; Clinical Trials as Topic; Drug Discovery; Drug Evaluation, Preclinical; Humans; Hydrolases; Neoplasms; Polyethylene Glycols

2019
The regulation, functions and clinical relevance of arginine methylation.
    Nature reviews. Molecular cell biology, 2019, Volume: 20, Issue:10

    Topics: Animals; Arginine; Humans; Methylation; Neoplasm Proteins; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Signal Transduction

2019
SRp20: an overview of its role in human diseases.
    Biochemical and biophysical research communications, 2013, Jun-21, Volume: 436, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Arginine; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neoplasms; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; RNA Splicing; RNA-Binding Proteins; RNA, Messenger; RNA, Small Nuclear; Sequence Homology, Amino Acid; Serine; Serine-Arginine Splicing Factors

2013
Defining the RGG/RG motif.
    Molecular cell, 2013, Jun-06, Volume: 50, Issue:5

    Topics: Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Apoptosis; Arginine; DNA Damage; Fragile X Syndrome; Humans; Methylation; Molecular Sequence Data; Neoplasms; Neuromuscular Diseases; Protein Biosynthesis; Protein Interaction Domains and Motifs; Proteins

2013
Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities.
    Cancer discovery, 2013, Volume: 3, Issue:7

    Topics: Animals; Arginine; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knock-In Techniques; Glutarates; Humans; Isocitrate Dehydrogenase; Mice; Mutation; Neoplasms

2013
Association between the XRCC1 Arg399Gln polymorphism and risk of cancer: evidence from 297 case-control studies.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Arginine; Asian People; Case-Control Studies; DNA-Binding Proteins; Genetic Predisposition to Disease; Humans; Neoplasms; X-ray Repair Cross Complementing Protein 1

2013
The role of arginine and the modified arginine deiminase enzyme ADI-PEG 20 in cancer therapy with special emphasis on Phase I/II clinical trials.
    Expert opinion on investigational drugs, 2014, Volume: 23, Issue:11

    Topics: Animals; Antineoplastic Agents; Arginine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Humans; Hydrolases; Molecular Targeted Therapy; Neoplasms; Polyethylene Glycols; Randomized Controlled Trials as Topic

2014
On the importance of electrostatic interactions between cell penetrating peptides and membranes: a pathway toward tumor cell selectivity?
    Biochimie, 2014, Volume: 107 Pt A

    Topics: Amino Acid Sequence; Arginine; Cell Membrane; Cell-Penetrating Peptides; Humans; Models, Biological; Molecular Sequence Data; Neoplasms; Protein Binding; Static Electricity

2014
Recombinant arginine-degrading enzymes in metabolic anticancer therapy and bioanalytics.
    Cell biology international, 2015, Volume: 39, Issue:3

    Topics: Antineoplastic Agents; Arginase; Arginine; Humans; Hydrolases; Neoplasms; Recombinant Proteins

2015
Arginine deprivation in cancer therapy.
    Current opinion in clinical nutrition and metabolic care, 2015, Volume: 18, Issue:1

    Topics: Antineoplastic Agents; Arginase; Arginine; Argininosuccinate Synthase; Humans; Hydrolases; Neoplasms; Polyethylene Glycols

2015
Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options.
    Autoimmunity, 2015, Volume: 48, Issue:2

    Topics: Arginine; Arthritis, Rheumatoid; Autoantibodies; Benzamidines; Biomarkers; Citrulline; Enzyme Inhibitors; Fibrosis; Humans; Hydrolases; Isoenzymes; Multiple Sclerosis; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Spondylitis, Ankylosing

2015
The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.
    Cellular and molecular life sciences : CMLS, 2015, Volume: 72, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Arginine; Catalytic Domain; Cell Differentiation; Gene Expression Regulation; Histones; Humans; Methylation; Multiprotein Complexes; Neoplasms; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Quaternary; Protein-Arginine N-Methyltransferases

2015
Isocitrate dehydrogenase mutations: new opportunities for translational research.
    BMB reports, 2015, Volume: 48, Issue:5

    Topics: Arginine; Enzyme Inhibitors; Glutarates; Humans; Isocitrate Dehydrogenase; Isoenzymes; Mutation, Missense; Neoplasms; Translational Research, Biomedical

2015
Targeting arginine metabolism pathway to treat arginine-dependent cancers.
    Cancer letters, 2015, Aug-01, Volume: 364, Issue:1

    Topics: Arginine; Cell Death; Humans; Neoplasms

2015
Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches.
    Current medicinal chemistry, 2015, Volume: 22, Issue:24

    Topics: Alzheimer Disease; Animals; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hypercholesterolemia; Neoplasms; Pre-Eclampsia; Pregnancy; Renal Insufficiency, Chronic

2015
Prevention and treatment of cancers by immune modulating nutrients.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:6

    Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes

2016
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
    International journal of cancer, 2016, 08-01, Volume: 139, Issue:3

    Topics: Animals; Antineoplastic Agents; Arginase; Arginine; Cell Proliferation; Cell Survival; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Therapy; Humans; Hydrolases; Metabolic Networks and Pathways; Neoplasms; Signal Transduction; Stress, Physiological

2016
Occurrence, Functions and Biological Significance of Arginine-Rich Proteins.
    Current protein & peptide science, 2016, Volume: 17, Issue:5

    Topics: Amino Acids; Arginine; Dietary Proteins; Humans; Neoplasms; Proteins; Virus Diseases

2016
Arginine Metabolism in Bacterial Pathogenesis and Cancer Therapy.
    International journal of molecular sciences, 2016, Mar-11, Volume: 17, Issue:3

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Arginase; Arginine; Bacteria; Bacterial Infections; Drug Resistance, Bacterial; Gene Expression Regulation; Humans; Hydrolases; Neoplasms; Signal Transduction

2016
Arginine dependence of tumor cells: targeting a chink in cancer's armor.
    Oncogene, 2016, 09-22, Volume: 35, Issue:38

    Topics: Arginase; Arginine; Argininosuccinate Synthase; Gene Expression Regulation, Neoplastic; Humans; Hydrolases; Neoplasms; Ornithine Carbamoyltransferase; Signal Transduction

2016
[Methionine metabolism regulates biotransformation of glucose via protein arginine methylation in cancer cells].
    Seikagaku. The Journal of Japanese Biochemical Society, 2016, Volume: 88, Issue:3

    Topics: Animals; Arginine; Glucose; Humans; Methionine; Methylation; Neoplasms; Proteins

2016
Protein arginine methylation/demethylation and cancer.
    Oncotarget, 2016, Oct-11, Volume: 7, Issue:41

    Topics: Arginine; Demethylation; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasms; Protein Processing, Post-Translational

2016
Arginine-Dual roles as an onconutrient and immunonutrient.
    Journal of surgical oncology, 2017, Volume: 115, Issue:3

    Topics: Animals; Arginine; Dietary Supplements; Humans; Neoplasms

2017
The story of protein arginine methylation: characterization, regulation, and function.
    Expert review of proteomics, 2017, Volume: 14, Issue:2

    Topics: Arginine; Cardiovascular Diseases; DNA Repair; Humans; Mass Spectrometry; Methylation; Multiple Sclerosis; Muscular Atrophy, Spinal; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins; Proteomics; Signal Transduction

2017
Protein arginine methylation in health and disease.
    Biotechnology annual review, 2008, Volume: 14

    Topics: Animals; Arginine; Autoimmune Diseases; Cardiovascular Diseases; Humans; Methylation; Models, Biological; Neoplasms; Virus Diseases

2008
Dynamic protein methylation in chromatin biology.
    Cellular and molecular life sciences : CMLS, 2009, Volume: 66, Issue:3

    Topics: Animals; Arginine; Chromatin; DNA Damage; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Regulation; Germ Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Models, Molecular; Molecular Structure; Neoplasms; Oxidoreductases, N-Demethylating; Protein Conformation; Protein Methyltransferases; Protein Processing, Post-Translational; Tumor Suppressor Protein p53

2009
Arginine metabolism and nutrition in growth, health and disease.
    Amino acids, 2009, Volume: 37, Issue:1

    Topics: Animals; Arginine; Cystic Fibrosis; Fetal Development; Humans; Metabolic Syndrome; Muscle, Skeletal; Neoplasms; Nutritional Requirements; Obesity; Reproduction; Wounds and Injuries

2009
The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors.
    ChemMedChem, 2009, Volume: 4, Issue:10

    Topics: Arginine; Enzyme Inhibitors; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational

2009
Arginase: an emerging key player in the mammalian immune system.
    British journal of pharmacology, 2009, Volume: 158, Issue:3

    Topics: Animals; Arginase; Arginine; Autoimmune Diseases; Humans; Immune System; Immune Tolerance; Inflammation; Mammals; Myeloid Cells; Neoplasms; Signal Transduction

2009
Protein arginine methylation in estrogen signaling and estrogen-related cancers.
    Trends in endocrinology and metabolism: TEM, 2010, Volume: 21, Issue:3

    Topics: Animals; Arginine; Breast Neoplasms; Estrogens; Female; Humans; Male; Methylation; Models, Biological; Neoplasms; Protein-Arginine N-Methyltransferases; Receptors, Estrogen; Signal Transduction

2010
Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer.
    International journal of cancer, 2010, Jun-15, Volume: 126, Issue:12

    Topics: Animals; Arginine; Argininosuccinate Synthase; Humans; Neoplasms; Prognosis

2010
Targeting the L-arginine-nitric oxide pathway for cancer treatment.
    Current pharmaceutical design, 2010, Volume: 16, Issue:4

    Topics: Animals; Arginine; Humans; Neoplasms; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase

2010
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism.
    Journal of the National Cancer Institute, 2010, Jul-07, Volume: 102, Issue:13

    Topics: Animals; Arginine; Brain Neoplasms; Codon; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioblastoma; Glucose; Glutarates; Humans; Hypoxia; Isocitrate Dehydrogenase; Mutation; NADP; Neoplasms; Oligodendroglioma; Oncogenes; Signal Transduction; Up-Regulation

2010
Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes.
    Oncotarget, 2010, Volume: 1, Issue:4

    Topics: Antineoplastic Agents; Arginase; Arginine; Argininosuccinate Synthase; Autophagy; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Hydrolases; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Targeted Therapy; Neoplasms; Polyethylene Glycols; Sp4 Transcription Factor

2010
[Deimination or citrullination, a post-translational modification with many physiological and pathophysiological facets].
    Medecine sciences : M/S, 2011, Volume: 27, Issue:1

    Topics: Animals; Arginine; Autoimmune Diseases; Body Water; Calcium; Chromatin; Citrulline; Conserved Sequence; Cornea; Epidermis; Evolution, Molecular; Gene Expression Regulation; Humans; Hydrolases; Isoenzymes; Mice; Myelin Proteins; Neoplasms; Nervous System Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 6; Protein-Arginine Deiminases; Skin Diseases

2011
Nutritional intervention for improving treatment tolerance in cancer patients.
    Current opinion in oncology, 2011, Volume: 23, Issue:4

    Topics: Amino Acids; Arginine; Cachexia; Dietary Supplements; Fatty Acids, Omega-3; Feeding Behavior; Glutamine; Humans; Malnutrition; Neoplasms; Nutritional Status; Nutritional Support; Weight Loss

2011
The relationships of nutrients, routes of delivery, and immunocompetence.
    The Surgical clinics of North America, 2011, Volume: 91, Issue:4

    Topics: Arginine; Dietary Supplements; Enteral Nutrition; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Glutamine; Humans; Immune System; Immune Tolerance; Immunocompetence; Malnutrition; Neoplasms; Nutritional Support; Parenteral Nutrition; Parenteral Nutrition, Total; Perioperative Care; Surgical Procedures, Operative; Wounds and Injuries

2011
The role of a disturbed arginine/NO metabolism in the onset of cancer cachexia: a working hypothesis.
    Current medicinal chemistry, 2012, Volume: 19, Issue:31

    Topics: Arginine; Cachexia; Humans; Neoplasms; Nitric Oxide; Proteins

2012
Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives.
    Immunological investigations, 2012, Volume: 41, Issue:6-7

    Topics: Animals; Arginase; Arginine; Cytokines; Gene Expression Regulation, Neoplastic; Humans; Immune Tolerance; Inflammation; Mice; Myeloid Progenitor Cells; Neoplasm Proteins; Neoplasms; Signal Transduction; T-Lymphocytes

2012
PGE(2)-driven induction and maintenance of cancer-associated myeloid-derived suppressor cells.
    Immunological investigations, 2012, Volume: 41, Issue:6-7

    Topics: Animals; Arginase; Arginine; Chemokine CXCL12; Cyclooxygenase 2; Dinoprostone; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Myeloid Progenitor Cells; Neoplasms; Nitric Oxide Synthase Type II; Receptors, CXCR4; Signal Transduction; T-Lymphocytes

2012
Protein arginine methyltransferases and cancer.
    Nature reviews. Cancer, 2013, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Arginine; DNA Methylation; Humans; Neoplasms; Protein-Arginine N-Methyltransferases

2013
[Nutrition and tumoral growth].
    Revue medicale de la Suisse romande, 2002, Volume: 122, Issue:7

    Topics: Animals; Arginine; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Nucleotides; Rats

2002
[Modulation of immunity in cancerous patient : an weapon with double edges?].
    Revue medicale de la Suisse romande, 2002, Volume: 122, Issue:7

    Topics: Animals; Arginine; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Nucleotides; Treatment Outcome

2002
Controlling cancer by restricting arginine availability--arginine-catabolizing enzymes as anticancer agents.
    Anti-cancer drugs, 2004, Volume: 15, Issue:9

    Topics: Animals; Antineoplastic Agents; Arginase; Arginine; Carboxy-Lyases; Humans; Neoplasms

2004
[Arginine--metabolism and functions in the human organism].
    Postepy higieny i medycyny doswiadczalnej (Online), 2004, Volume: 58

    Topics: Adult; Animals; Arginase; Arginine; Creatine; Humans; Intestine, Small; Kidney; Liver; Neoplasms; Nitric Oxide; Renal Insufficiency; Wounds and Injuries

2004
Arginine transport in catabolic disease states.
    The Journal of nutrition, 2004, Volume: 134, Issue:10 Suppl

    Topics: Animals; Arginine; Biological Transport; Cell Membrane; Endothelium, Vascular; Humans; Infections; Inflammation; Intestinal Mucosa; Liver; Neoplasms; Wounds and Injuries

2004
Arginine and cancer.
    The Journal of nutrition, 2004, Volume: 134, Issue:10 Suppl

    Topics: Animals; Antibody Formation; Antineoplastic Agents; Apoptosis; Arginine; Biological Transport; Disease Progression; Drug Synergism; Humans; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Nitric Oxide

2004
Arginine deprivation and metabolomics: important aspects of intermediary metabolism in relation to the differential sensitivity of normal and tumour cells.
    Seminars in cancer biology, 2005, Volume: 15, Issue:4

    Topics: Arginine; Argininosuccinate Synthase; Cell Death; Cell Division; Citrulline; Humans; Neoplasms

2005
[Design and creation of cytomedicine for application to cell therapy].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:8

    Topics: Animals; Arginine; Capsules; Cell- and Tissue-Based Therapy; Dendritic Cells; Diabetes Mellitus; Drug Delivery Systems; Drug Design; Genetic Therapy; Humans; Immunotherapy; Immunotherapy, Active; Islets of Langerhans; Neoplasms; Polylysine; Regenerative Medicine

2005
[L-arginine: an amino acid with multiple effects].
    Wiener klinische Wochenschrift, 2005, Volume: 117, Issue:19-20

    Topics: Arginine; Asthma; Body Constitution; Cardiovascular Diseases; Dietary Supplements; Fracture Healing; Humans; Neoplasms

2005
Pegylated arginine deiminase: a novel anticancer enzyme agent.
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:7

    Topics: Amino Acid Sequence; Amino Acids; Animals; Antineoplastic Agents; Arginine; Argininosuccinate Synthase; Carcinoma, Hepatocellular; Citrulline; Clinical Trials as Topic; Dexamethasone; Dogs; Drug Screening Assays, Antitumor; Drug Synergism; Drugs, Investigational; Humans; Hydrolases; Liver Neoplasms; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Molecular Sequence Data; Mycoplasma hominis; Neoplasm Proteins; Neoplasms; Nutritional Requirements; Polyethylene Glycols; Rabbits; Randomized Controlled Trials as Topic; Recombinant Proteins; Skin Neoplasms; Species Specificity; Treatment Outcome

2006
[Arginine as a crucial amino acid in carcinogenesis and tumor growth].
    Postepy higieny i medycyny doswiadczalnej (Online), 2006, Volume: 60

    Topics: Adult; Animals; Apoptosis; Arginine; Biological Transport; Cell Transformation, Neoplastic; Child; Disease Progression; Humans; In Vitro Techniques; Neoplasms; Neovascularization, Pathologic

2006
Interplay between chromatin remodelers and protein arginine methyltransferases.
    Journal of cellular physiology, 2007, Volume: 213, Issue:2

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arginine; Chromatin; Chromosomal Proteins, Non-Histone; DNA Repair; Gene Expression Regulation; Histones; Humans; Isoenzymes; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases; Transcription Factors; Transcription, Genetic

2007
Myeloid-derived suppressor cells.
    Advances in experimental medicine and biology, 2007, Volume: 601

    Topics: Animals; Antigens; Arginine; Cell Differentiation; Epitopes; Humans; Immune Tolerance; Models, Biological; Myeloid Cells; Neoplasms; Peroxynitrous Acid; Reactive Oxygen Species; T-Lymphocytes; T-Lymphocytes, Regulatory; Transforming Growth Factor beta

2007
Role of arginine metabolism in immunity and immunopathology.
    Immunobiology, 2007, Volume: 212, Issue:9-10

    Topics: Animals; Arginase; Arginine; Autoimmune Diseases; Cytokines; Humans; Immunity; Immunity, Active; Immunity, Innate; Infections; Inflammation; Myeloid Cells; Neoplasms; Nitric Oxide Synthase; Wound Healing

2007
Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives.
    Immunological reviews, 2008, Volume: 222

    Topics: Animals; Arginase; Arginine; CD3 Complex; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Immune Tolerance; Immunotherapy; Mice; Models, Immunological; Myeloid Cells; Neoplasms; Signal Transduction; T-Lymphocytes; Tumor Escape

2008
On the mechanism of cyclic AMP-mediated growth arrest of solid tumors.
    Advances in cyclic nucleotide research, 1980, Volume: 12

    Topics: Animals; Arginine; Bucladesine; Cell Division; Cyclic AMP; Female; Humans; Kinetics; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Neoplasms; Neoplasms, Experimental; Nucleoproteins; Phosphorylation; Rats; Receptors, Cyclic AMP

1980
Current indications for intravenous nutritional support in oncology patients.
    Surgical oncology clinics of North America, 1995, Volume: 4, Issue:3

    Topics: Animals; Arginine; Glutamine; Humans; Neoplasms; Nutrition Assessment; Parenteral Nutrition, Total; Preoperative Care; Randomized Controlled Trials as Topic; Treatment Outcome

1995
Protein metabolism in the cancer patient.
    Biochimie, 1994, Volume: 76, Issue:8

    Topics: Amino Acids, Branched-Chain; Animals; Arginine; Carbon Isotopes; Deuterium; Fasting; Humans; Neoplasms; Protein Biosynthesis

1994
L-arginine and malignant disease: a potential therapeutic role?
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1994, Volume: 20, Issue:2

    Topics: Animals; Arginine; Humans; Neoplasms; Neoplasms, Experimental; Wound Healing

1994
The Sir David Cuthbertson Medal Lecture 1992. The immunological and metabolic effects of L-arginine in human cancer.
    The Proceedings of the Nutrition Society, 1993, Volume: 52, Issue:3

    Topics: Animals; Arginine; Cell Division; Humans; Neoplasms; Nutritional Requirements

1993
The L-arginine/nitric oxide pathway--biological properties and therapeutic applications.
    The Ulster medical journal, 1994, Volume: 63, Issue:2

    Topics: Animals; Arginine; Child; Disease Models, Animal; Female; Humans; Neoplasms; Nitric Oxide; Sepsis; Wounds and Injuries

1994
Nutritional pharmacology and malignant disease: a therapeutic modality in patients with cancer.
    The British journal of surgery, 1996, Volume: 83, Issue:5

    Topics: Animals; Arginine; Cell Division; Fatty Acids, Essential; Glutamine; Humans; Immunity; Neoplasms; Nitrogen; Polyribonucleotides; Wound Healing

1996
NO-synthase: what can research on invertebrates add to what is already known?
    Advances in neuroimmunology, 1995, Volume: 5, Issue:4

    Topics: Animals; Arginine; Cell Death; Cytokines; Cytotoxicity, Immunologic; Endothelium, Vascular; Humans; Immunity, Cellular; Killer Cells, Natural; Macrophages; Mast Cells; Microglia; Neoplasms; Neutrophils; Nitric Oxide; Nitric Oxide Synthase

1995
Clinical significance of L-arginine--nitric oxide system.
    The Journal of the Association of Physicians of India, 1995, Volume: 43, Issue:2

    Topics: Arginine; Arteriosclerosis; Endothelium, Vascular; Humans; Neoplasms; Nitric Oxide

1995
Design of nitric oxide synthase inhibitors and their use to reverse hypotension associated with cancer immunotherapy.
    Advances in enzyme regulation, 1997, Volume: 37

    Topics: Animals; Arginine; Blood Pressure; Dogs; Drug Design; Enzyme Inhibitors; Humans; Hypotension; Immunotherapy; Interleukin-2; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine

1997
Erratic behavior of nitric oxide within the immune system: illustrative review of conflicting data and their immunopharmacological aspects.
    International journal of immunopharmacology, 1998, Volume: 20, Issue:7

    Topics: Animals; Apoptosis; Arginine; Autoimmune Diseases; Cytokines; Cytotoxicity, Immunologic; Encephalomyelitis, Autoimmune, Experimental; Endotoxemia; Histocompatibility Antigens Class II; Humans; Immune System; Infections; Inflammatory Bowel Diseases; Isoenzymes; Mice; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Species Specificity

1998
[Effects of dietetic supplementation with L-arginine in cancer patients. A review of the literature].
    Archivos latinoamericanos de nutricion, 1999, Volume: 49, Issue:4

    Topics: Animals; Arginine; Dietary Supplements; Humans; Neoplasms; Nutrition Disorders

1999
Glutamine and arginine: immunonutrients for improved health.
    Medicine and science in sports and exercise, 2000, Volume: 32, Issue:7 Suppl

    Topics: Arginine; Burns; Dietary Supplements; Glutamine; Health Status; HIV Infections; Humans; Immunity, Cellular; Immunocompromised Host; Infections; Neoplasms

2000
[Anti-cancer therapy with amino acid imbalance].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59 Suppl 5

    Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine

2001
Anticoagulation: the present and future.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:3

    Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis

2001
Is immune nutrition the Holy Grail for cancer patients?
    Nestle Nutrition workshop series. Clinical & performance programme, 2000, Volume: 4

    Topics: Arginine; Fatty Acids, Unsaturated; Glutamine; Hospitalization; Humans; Immunotherapy; Length of Stay; Neoplasms; Nutritional Physiological Phenomena; Nutritional Support; Ornithine; Treatment Outcome

2000
Arginine catabolism, liver extracts and cancer.
    Pathology oncology research : POR, 2002, Volume: 8, Issue:1

    Topics: Animals; Arginase; Arginine; Carboxy-Lyases; Cell Cycle; Food Deprivation; Humans; Hydrolases; Liver; Liver Extracts; Neoplasms; Tumor Cells, Cultured

2002
[Plasma clotting system in neoplastic diseases].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1976, Jul-05, Volume: 31, Issue:27

    Topics: Animals; Arginine; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Disseminated Intravascular Coagulation; Humans; Neoplasms; Platelet Aggregation; Thrombophlebitis; Thrombosis

1976
Overproduction of nitric oxide in cytokine-mediated and septic shock.
    Journal of the National Cancer Institute, 1992, Jun-03, Volume: 84, Issue:11

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cytokines; Humans; Interleukin-2; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic

1992
NO synthases: mechanism of activation, identity of NOX and expression in human cells.
    Research in immunology, 1991, Volume: 142, Issue:7

    Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Animals; Arginine; Enzyme Activation; Humans; Neoplasms; Nitric Oxide Synthase; Nitrogen Oxides; Parasites

1991
Future prospects for adjunctive therapy: pharmacologic and nutritional approaches to immune system modulation.
    Critical care medicine, 1990, Volume: 18, Issue:2 Suppl

    Topics: Animals; Arginine; Autoimmune Diseases; Humans; Immunity; Infections; Neoplasms; Nutritional Physiological Phenomena; Transplantation Immunology

1990
Dietary immunomodulation: beneficial effects on oncogenesis and tumor growth.
    Critical care medicine, 1990, Volume: 18, Issue:2 Suppl

    Topics: Animals; Arginine; Dietary Fats; Humans; Immunity; Neoplasms

1990
[Mechanisms of macrophage activation and macrophage-mediated tumoricidal activity].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1989, Volume: 16, Issue:10

    Topics: Arginine; Cytotoxicity, Immunologic; Humans; Interferon-gamma; Macrophage Activation; Macrophages; Neoplasms; Signal Transduction; Tumor Necrosis Factor-alpha

1989
Tumour-associated hormonal products.
    Journal of clinical pathology. Supplement (Royal College of Pathologists), 1974, Volume: 7

    Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Arginine; Biliary Tract Diseases; Bronchial Neoplasms; Carcinoma; Chorionic Gonadotropin; Colonic Neoplasms; Cushing Syndrome; Erythropoietin; Female; Follicle Stimulating Hormone; Growth Hormone; Gynecomastia; Hormones, Ectopic; Humans; Hypercalcemia; Lactation Disorders; Lung Neoplasms; Luteinizing Hormone; Models, Biological; Neoplasms; Paraganglioma; Paraneoplastic Endocrine Syndromes; Polycythemia; Pregnancy; Prolactin; Thyroid Neoplasms; Vasopressins

1974
[Regulation of DNA biosynthesis and cell division].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1971, Volume: 16, Issue:9

    Topics: Arginine; Carbon Isotopes; Cell Division; Cell Membrane; DNA; DNA, Bacterial; Electrophoresis; Escherichia coli; Leucine; Neoplasms; Peptide Hydrolases; Proteins; Temperature; Thymine; Triazines; Trypsin

1971
Pulmonary complications of novel antineoplastic agents for solid tumors.
    Chest, 2008, Volume: 133, Issue:2

    Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bevacizumab; Deoxycytidine; Doxorubicin; Epirubicin; Etoposide; Everolimus; Gemcitabine; Humans; Lung; Lung Diseases; Mitoxantrone; Neoplasms; Pneumonia; Pyrimidines; Risk Factors; Sirolimus; Teniposide; Trastuzumab

2008
[New antineoplastic agents, their value and use].
    Przeglad lekarski, 1982, Volume: 39, Issue:8

    Topics: Aminacrine; Antineoplastic Agents; Aspartic Acid; Cisplatin; Etoposide; Humans; Ifosfamide; Interferons; Medroxyprogesterone; Medroxyprogesterone Acetate; Methyltestosterone; Neoplasms; Phosphonoacetic Acid; Razoxane; Tamoxifen; Teniposide; Vinca Alkaloids

1982
Teniposide: a review of 12 years of experience.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide

1984
The podophyllotoxin derivatives VP16-213 and VM26.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Animals; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Etoposide; Humans; Neoplasms; Podophyllotoxin; Teniposide

1982
VM26: phase I and II studies.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Drug Evaluation; Humans; Neoplasms; Podophyllotoxin; Teniposide

1982
Teniposide: overview of its therapeutic potential in adult cancers.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

    Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Etoposide; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma, Kaposi; Teniposide

1994
Schedule-dependent topoisomerase II-inhibiting drugs.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

    Topics: Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Cycle; Clinical Trials, Phase I as Topic; DNA Repair; Drug Administration Schedule; Etoposide; Humans; Metabolic Clearance Rate; Neoplasms; Teniposide; Topoisomerase II Inhibitors

1994
Epipodophyllotoxins in the treatment of childhood cancer.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34 Suppl

    Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Second Primary; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide

1994
Clinical pharmacokinetics and pharmacodynamics of epipodophyllotoxins.
    Cancer surveys, 1993, Volume: 17

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Etoposide; Humans; Leukemia; Neoplasms; Neoplasms, Second Primary; Teniposide; Topoisomerase II Inhibitors

1993
[DNA topoisomerases targeting anticancer agents and mechanism for acquirement of drug resistance].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Humans; Irinotecan; Mutation; Neoplasms; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1997
Etoposide: four decades of development of a topoisomerase II inhibitor.
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:10

    Topics: Administration, Oral; Anthracyclines; Antineoplastic Agents, Phytogenic; Etoposide; Humans; Mitoxantrone; Neoplasms; Technology, Pharmaceutical; Teniposide; Topoisomerase II Inhibitors

1998
DNA topoisomerase II inhibitors.
    IARC monographs on the evaluation of carcinogenic risks to humans, 2000, Volume: 76

    Topics: Amsacrine; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Etoposide; Evidence-Based Medicine; Humans; Intestinal Absorption; Mitoxantrone; Neoplasms; Nucleic Acid Synthesis Inhibitors; Research Design; Risk Factors; Teniposide; Tissue Distribution; Topoisomerase II Inhibitors

2000
Investigational drugs under study by the United States National Cancer Institute.
    Cancer treatment reviews, 1976, Volume: 3, Issue:1

    Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Chemical Phenomena; Chemistry; Chromomycins; Cisplatin; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Humans; Ifosfamide; Leukemia L1210; Mice; Mitosis; National Institutes of Health (U.S.); Neoplasms; Neoplasms, Experimental; Razoxane; Tegafur; Teniposide; United States

1976
Pharmacology of antitumor agents from higher plants.
    Cancer treatment reports, 1976, Volume: 60, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine

1976
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
    Cancer treatment reviews, 1979, Volume: 6, Issue:3

    Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide

1979
Hypersensitivity reactions.
    Seminars in oncology, 1992, Volume: 19, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide

1992
Teniposide in adult solid tumors: a historical perspective.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 6

    Topics: Adult; Animals; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Neoplasms; Teniposide

1992
Disposition of antineoplastic agents in the very young child.
    The British journal of cancer. Supplement, 1992, Volume: 18

    Topics: Age Factors; Antineoplastic Agents; Blood Proteins; Child; Child, Preschool; Doxorubicin; Etoposide; Humans; Infant; Infant, Newborn; Liver; Mercaptopurine; Methotrexate; Neoplasms; Nervous System; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide

1992
Podophyllotoxin derivatives.
    Cancer chemotherapy and biological response modifiers, 1991, Volume: 12

    Topics: Animals; Drug Interactions; Drug Resistance; Etoposide; Humans; Neoplasms; Teniposide

1991

Trials

13 trial(s) available for arginine and Neoplasms

ArticleYear
Arginase-1 targeting peptide vaccine in patients with metastatic solid tumors - A phase I trial.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Arginase; Arginine; Cancer Vaccines; Humans; Leukocytes, Mononuclear; Neoplasms; Peptides; Tumor Microenvironment; Vaccines, Subunit

2022
    American journal of obstetrics & gynecology MFM, 2021, Volume: 3, Issue:1

    Topics: Adipose Tissue, White; Adult; Aged; Air Pollutants; Animals; Anti-Inflammatory Agents; Arginine; bcl-2-Associated X Protein; Biofuels; Biological Products; Blood Glucose; Breast Neoplasms; Caspases; CD36 Antigens; Cell Communication; Cell Proliferation; Cell Survival; Cooking; Cross-Sectional Studies; Databases, Factual; Diabetes Mellitus, Type 2; Diphtheria Toxin; Double-Blind Method; Exenatide; Extracellular Polymeric Substance Matrix; Feasibility Studies; Female; Filgrastim; Fruit; Galactose; Gene Deletion; Gene Knockdown Techniques; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Glucose; Glycated Hemoglobin; Hematopoietic Stem Cell Mobilization; Household Articles; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Lung; Lymphoma; Male; Metals, Heavy; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Nanoparticles; Neoplasms; Obesity; Obstetrics; Odds Ratio; Oxygen; Peripheral Blood Stem Cell Transplantation; Photochemotherapy; Plant Extracts; Polyethylene Glycols; Polyglutamic Acid; Porosity; Postprandial Period; Prospective Studies; Quality of Life; Receptors, Glucagon; Receptors, LDL; Receptors, Somatostatin; Registries; Rhodophyta; Rhodotorula; Risk Factors; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Somatostatin; Stilbenes; Terminalia; Treatment Outcome; United States; Venoms

2021
Arginine, glutamine, and fish oil supplementation in cancer patients treated with concurrent chemoradiotherapy: A randomized control study.
    Current problems in cancer, 2020, Volume: 44, Issue:1

    Topics: Arginine; Chemoradiotherapy; Dietary Supplements; Female; Fish Oils; Glutamine; Hematologic Diseases; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasms; Patient Compliance; Severity of Illness Index; Treatment Outcome

2020
Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2015, Jun-01, Volume: 21, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arginine; Docetaxel; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydrolases; Male; Neoplasm Staging; Neoplasms; Polyethylene Glycols; Taxoids; Treatment Outcome

2015
A randomized, double-blind, placebo-controlled trial of a beta-hydroxyl beta-methyl butyrate, glutamine, and arginine mixture for the treatment of cancer cachexia (RTOG 0122).
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2008, Volume: 16, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Arginine; Cachexia; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Placebos; Plethysmography; Quality of Life; Statistics, Nonparametric; Treatment Outcome; Valerates

2008
Metabolic and immune effects of dietary arginine, glutamine and omega-3 fatty acids supplementation in immunocompromised patients.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1998, Volume: 81, Issue:5

    Topics: Adult; Arginine; Burns; CD4-CD8 Ratio; Dietary Supplements; Enteral Nutrition; Fatty Acids, Omega-3; Female; Glutamine; Humans; Immunocompromised Host; Immunoglobulins; Lymphocyte Count; Male; Middle Aged; Neoplasms; Nutritional Status; Phenotype; Prospective Studies; Treatment Outcome; Wounds and Injuries

1998
Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine.
    American journal of surgery, 2002, Volume: 183, Issue:4

    Topics: Aged; Arginine; Body Composition; Cachexia; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Glutamine; Humans; Male; Middle Aged; Muscle, Skeletal; Neoplasms; Treatment Outcome; Valerates

2002
[New antineoplastic drugs of the podophyllotoxin derivative group].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1983, Jan-03, Volume: 38, Issue:1

    Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1983
Teniposide: a review of 12 years of experience.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide

1984
Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.
    British journal of cancer, 1999, Volume: 79, Issue:5-6

    Topics: Adult; Aged; Alanine Transaminase; Alkenes; Antibiotics, Antineoplastic; Aspartate Aminotransferases; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Half-Life; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Polyenes; Pyrones; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1999
Phase II study of VM-26 in acute leukemia, neuroblastoma, and other refractory childhood malignancies: a report from the Children's Cancer Study Group.
    Cancer treatment reports, 1979, Volume: 63, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Child; Clinical Trials as Topic; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Neoplasms; Neuroblastoma; Podophyllotoxin; Remission, Spontaneous; Teniposide

1979
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
    Cancer treatment reviews, 1979, Volume: 6, Issue:3

    Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide

1979
Absolute bioavailability and pharmacokinetics of oral teniposide.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 6

    Topics: Absorption; Administration, Oral; Adult; Aged; Biological Availability; Clinical Trials, Phase I as Topic; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Teniposide; Time Factors

1992

Other Studies

229 other study(ies) available for arginine and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.
    Bioorganic & medicinal chemistry letters, 2019, 08-15, Volume: 29, Issue:16

    Topics: Antineoplastic Agents; Brain Diseases; Click Chemistry; Dose-Response Relationship, Drug; Histidine; Humans; Large Neutral Amino Acid-Transporter 1; Molecular Structure; Neoplasms; Prodrugs; Structure-Activity Relationship; Triazoles; Tryptophan

2019
Engineered Bacteria Increase L-Arginine to Improve Immunotherapy Response.
    Cancer discovery, 2021, 12-01, Volume: 11, Issue:12

    Topics: Arginine; Bacteria; Humans; Immunotherapy; Neoplasms

2021
Near infrared light triggered ternary synergistic cancer therapy via L-arginine-loaded nanovesicles with modification of PEGylated indocyanine green.
    Acta biomaterialia, 2022, 03-01, Volume: 140

    Topics: Animals; Arginine; Cell Line, Tumor; Humans; Indocyanine Green; Mice; Mice, Nude; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Phototherapy; Polyethylene Glycols

2022
Armet from whitefly saliva acts as an effector to suppress plant defences by targeting tobacco cystatin.
    The New phytologist, 2022, Volume: 234, Issue:5

    Topics: Animals; Arginine; Cystatins; Hemiptera; Mammals; Neoplasms; Nicotiana; Plants; Saliva

2022
Mechanisms of selective monocyte targeting by liposomes functionalized with a cationic, arginine-rich lipopeptide.
    Acta biomaterialia, 2022, Volume: 144

    Topics: Animals; Arginine; Autoimmune Diseases; Cations; Humans; Lipopeptides; Lipopolysaccharide Receptors; Liposomes; Mice; Monocytes; Neoplasms

2022
Endocytosis Involved d-Oligopeptide of Tryptophan and Arginine Displays Ordered Nanostructures and Cancer Cell Stereoselective Toxicity by Autophagy.
    ACS applied materials & interfaces, 2022, Apr-06, Volume: 14, Issue:13

    Topics: Arginine; Autophagy; Cell Line, Tumor; Endocytosis; Humans; Nanostructures; Neoplasms; Oligopeptides; Tryptophan

2022
Global analysis of protein arginine methylation.
    Cell reports methods, 2021, 06-21, Volume: 1, Issue:2

    Topics: Animals; Arginine; Methylation; Mice; Neoplasms; Protein Processing, Post-Translational; Proteins

2021
Solvation, Cancer Cell Photoinactivation and the Interaction of Chlorin Photosensitizers with a Potential Passive Carrier Non-Ionic Surfactant Tween 80.
    International journal of molecular sciences, 2022, May-10, Volume: 23, Issue:10

    Topics: Arginine; Excipients; Galactose; Humans; Lipids; Micelles; Neoplasms; Photosensitizing Agents; Polysorbates; Porphyrins; Pulmonary Surfactants; Surface-Active Agents

2022
The association between symmetric dimethylarginine concentrations and various neoplasms in dogs and cats.
    Veterinary and comparative oncology, 2022, Volume: 20, Issue:4

    Topics: Animals; Arginine; Biomarkers; Case-Control Studies; Cat Diseases; Cats; Dog Diseases; Dogs; Neoplasms; Retrospective Studies

2022
A peptoid-based inhibitor of protein arginine methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:8

    Topics: Apoptosis; Arginine; Autophagy; Humans; Neoplasms; Peptoids; Protein-Arginine N-Methyltransferases; Repressor Proteins

2022
Arginine methylation of MTHFD1 by PRMT5 enhances anoikis resistance and cancer metastasis.
    Oncogene, 2022, Volume: 41, Issue:32

    Topics: Anoikis; Arginine; Formate-Tetrahydrofolate Ligase; Humans; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Neoplasms; Protein-Arginine N-Methyltransferases

2022
Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy.
    Bosnian journal of basic medical sciences, 2022, Oct-23, Volume: 22, Issue:6

    Topics: Antineoplastic Agents; Arginine; Camptothecin; Cell Line, Tumor; Humans; Lactones; Lysine; Mitochondria; Neoplasms; Prodrugs; Reactive Oxygen Species; Water

2022
PRMT5 activates AKT via methylation to promote tumor metastasis.
    Nature communications, 2022, 07-08, Volume: 13, Issue:1

    Topics: Arginine; Cell Line, Tumor; Humans; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt

2022
Integrated Transcriptome and Metabolomic Analysis Reveal Anti-Angiogenic Properties of Disarib, a Novel Bcl2-Specific Inhibitor.
    Genes, 2022, 07-06, Volume: 13, Issue:7

    Topics: Animals; Antineoplastic Agents; Arginine; Indoles; Mice; Neoplasms; Neovascularization, Pathologic; Oleic Acid; Thiadiazoles; Transcriptome

2022
Platinum-based nanocomposites loaded with MTH1 inhibitor amplify oxidative damage for cancer therapy.
    Colloids and surfaces. B, Biointerfaces, 2022, Volume: 218

    Topics: Arginine; Aspartic Acid; Catalase; Cell Line, Tumor; Glycine; Humans; Hydrogen Peroxide; Liposomes; Metal Nanoparticles; Nanocomposites; Nanoparticles; Neoplasms; Nucleotides; Oligopeptides; Oxidative Stress; Oxygen; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species; Silicon Dioxide; Singlet Oxygen

2022
Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile.
    Journal of the American Chemical Society, 2022, 09-07, Volume: 144, Issue:35

    Topics: Arginine; Genes, ras; Humans; Ligands; Mutation; Neoplasms; Proto-Oncogene Proteins p21(ras)

2022
Reactive oxygen species-responsive branched poly (β-amino ester) with robust efficiency for cytosolic protein delivery.
    Acta biomaterialia, 2022, 10-15, Volume: 152

    Topics: Arginine; Boronic Acids; Esters; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Nitrogen; Polymers; Reactive Oxygen Species; Saporins

2022
An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer.
    BMC cancer, 2022, Sep-12, Volume: 22, Issue:1

    Topics: Arginine; Cell Line, Tumor; Fatty Acid Synthases; Insulin-Like Growth Factor I; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; RNA; RNA, Messenger; Serine

2022
The Structural Effects of Phosphorylation of Protein Arginine Methyltransferase 5 on Its Binding to Histone H4.
    International journal of molecular sciences, 2022, Sep-26, Volume: 23, Issue:19

    Topics: Adaptor Proteins, Signal Transducing; Arginine; Histones; Humans; Neoplasms; Nucleosomes; Phosphorylation; Protein Binding; Protein-Arginine N-Methyltransferases

2022
Design, Synthesis and Biological Evaluation of Novel and Potent Protein Arginine Methyltransferases 5 Inhibitors for Cancer Therapy.
    Molecules (Basel, Switzerland), 2022, Oct-06, Volume: 27, Issue:19

    Topics: Arginine; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Humans; Neoplasms; Protein-Arginine N-Methyltransferases; Tetrahydroisoquinolines

2022
Arginine methylation of BRD4 by PRMT2/4 governs transcription and DNA repair.
    Science advances, 2022, 12-09, Volume: 8, Issue:49

    Topics: Arginine; Cell Cycle Proteins; Chromatin; DNA; DNA Repair; Humans; Intracellular Signaling Peptides and Proteins; Neoplasms; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Transcription Factors

2022
Dynamic tagging to drive arginine nano-assembly to metabolically potentiate immune checkpoint blockade therapy.
    Biomaterials, 2023, Volume: 292

    Topics: Animals; Arginine; Cell Line, Tumor; Immune Checkpoint Inhibitors; Immunotherapy; Mice; Neoplasms; Tumor Microenvironment

2023
Unraveling the Structural Changes in the DNA-Binding Region of Tumor Protein p53 (
    International journal of molecular sciences, 2022, Dec-07, Volume: 23, Issue:24

    Topics: Arginine; Codon; DNA; Humans; Mutation; Neoplasms; Protein Binding; Tumor Suppressor Protein p53

2022
Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
    Bioorganic & medicinal chemistry letters, 2023, 03-15, Volume: 84

    Topics: Arginase; Arginine; Boronic Acids; Enzyme Inhibitors; Humans; Models, Molecular; Neoplasms

2023
An L-arginine-functionalized pillar[5]arene-based supramolecular photosensitizer for synergistically enhanced cancer therapeutic effectiveness.
    Chemical communications (Cambridge, England), 2023, Mar-16, Volume: 59, Issue:23

    Topics: Arginine; Calixarenes; Humans; Micelles; Neoplasms; Photosensitizing Agents; Quaternary Ammonium Compounds

2023
Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications.
    Balkan medical journal, 2023, 03-08, Volume: 40, Issue:2

    Topics: Antineoplastic Agents; Arginine; Biomarkers; Cardiotoxicity; Echocardiography; Glycopeptides; Heart Injuries; Humans; Neoplasms

2023
Ultrasound-Induced Piezocatalysis Triggered NO Generation for Enhanced Hypoxic Tumor Therapy.
    ACS applied materials & interfaces, 2023, Mar-29, Volume: 15, Issue:12

    Topics: Arginine; Cell Line, Tumor; Humans; Hydrogen Peroxide; Hypoxia; Nanoparticles; Neoplasms; Photochemotherapy; Reactive Oxygen Species; Tumor Microenvironment

2023
Protein Arginine Methyltransferase 5 (PRMT5) Mutations in Cancer Cells.
    International journal of molecular sciences, 2023, Mar-23, Volume: 24, Issue:7

    Topics: Arginine; Artificial Intelligence; Histones; Humans; Mutation; Neoplasms; Protein-Arginine N-Methyltransferases

2023
Defects in intratumoral arginine metabolism attenuate the replication and therapeutic efficacy of oncolytic myxoma virus.
    Journal for immunotherapy of cancer, 2023, Volume: 11, Issue:6

    Topics: Arginine; Citrulline; Humans; Myxoma virus; Neoplasms; Oncolytic Viruses

2023
Research Progress on Small-molecule Inhibitors of Protein Arginine Methyltransferase 5 (PRMT5) for Treating Cancer.
    Current topics in medicinal chemistry, 2023, Volume: 23, Issue:21

    Topics: Arginine; Cell Line, Tumor; Enzyme Inhibitors; Humans; Neoplasms; Protein-Arginine N-Methyltransferases

2023
L-Arginine self-delivery supramolecular nanodrug for NO gas therapy.
    Acta biomaterialia, 2023, 10-01, Volume: 169

    Topics: Apoptosis; Arginine; Cell Line, Tumor; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Tumor Microenvironment

2023
A novel self-assembled nucleobase-nanofiber platform of CDN to activate the STING pathway for synergistic cancer immunotherapy.
    Colloids and surfaces. B, Biointerfaces, 2023, Volume: 232

    Topics: Animals; Arginine; Immunotherapy; Mice; Nanofibers; Neoplasms; Thymine

2023
A double-gain theranostic nanoplatform based on self-supplying H
    Journal of colloid and interface science, 2024, Jan-15, Volume: 654, Issue:Pt A

    Topics: Arginine; Cell Line, Tumor; Glutathione; Humans; Hydrogen Peroxide; Nanocomposites; Neoplasms; Nitric Oxide; Precision Medicine

2024
[Bacteria engineered to produce L-arginine potentiate cancer immunotherapy].
    Medecine sciences : M/S, 2023, Volume: 39, Issue:10

    Topics: Arginine; Bacteria; Humans; Immunotherapy; Neoplasms

2023
Molecular characteristics and clinical implications of serine/arginine-rich splicing factors in human cancer.
    Aging, 2023, 11-24, Volume: 15, Issue:22

    Topics: Alternative Splicing; Arginine; Humans; Neoplasms; Serine; Serine-Arginine Splicing Factors

2023
Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.
    Oncogene, 2020, Volume: 39, Issue:3

    Topics: Amino Acid Substitution; Arginine; Calmodulin-Binding Proteins; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Neoplasms; Nerve Tissue Proteins; Protein Kinase Inhibitors; Protein Phosphatase 2; Recombinant Proteins; Transfection; Tyrosine; Xenograft Model Antitumor Assays

2020
Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns.
    Nucleic acids research, 2019, 12-02, Volume: 47, Issue:21

    Topics: 5' Flanking Region; Amino Acid Substitution; Arginine; Binding Sites; Catalytic Domain; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; HCT116 Cells; Histidine; Humans; Mutation, Missense; Neoplasms; Substrate Specificity

2019
Tailoring Synthetic Melanin Nanoparticles for Enhanced Photothermal Therapy.
    ACS applied materials & interfaces, 2019, Nov-13, Volume: 11, Issue:45

    Topics: Animals; Arginine; Female; Humans; Hyperthermia, Induced; Melanins; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Phototherapy

2019
Helix Self-Assembly Behavior of Amino Acid-Modified Camptothecin Prodrugs and Its Antitumor Effect.
    ACS applied materials & interfaces, 2020, Feb-12, Volume: 12, Issue:6

    Topics: Animals; Antineoplastic Agents; Arginine; Camptothecin; Carbon; Cell Line, Tumor; Cisplatin; Drug Delivery Systems; Female; Humans; Mice; Nanofibers; Neoplasms; Prodrugs; Solubility

2020
Indospicine combined with arginine deprivation triggers cancer cell death via caspase-dependent apoptosis.
    Cell biology international, 2021, Volume: 45, Issue:3

    Topics: Apoptosis; Arginase; Arginine; Cell Line, Tumor; Cell Survival; Humans; Neoplasms; Norleucine; Protein Biosynthesis; Signal Transduction; Substrate Specificity

2021
High-Throughput Fluorescence-Based Activity Assay for Arginase-1.
    SLAS discovery : advancing life sciences R & D, 2020, Volume: 25, Issue:9

    Topics: Arginase; Arginine; Enzyme Inhibitors; Fluorescence; High-Throughput Screening Assays; Humans; Neoplasms; Ornithine; T-Lymphocytes

2020
Supplementation of l-arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy.
    Cancer science, 2020, Volume: 111, Issue:7

    Topics: Amino Acids; Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; Arginine; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cyclophosphamide; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Female; Flow Cytometry; Mice; Myeloid-Derived Suppressor Cells; Neoplasms; T-Lymphocyte Subsets

2020
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
    BMC cancer, 2020, Jul-16, Volume: 20, Issue:1

    Topics: Apoptosis; Arginine; Autophagy; Cell Line, Tumor; Chromatin; Cytosol; Ferritins; Histones; Humans; Hydrolases; Mitochondria; Neoplasms; Polyethylene Glycols

2020
Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues.
    Scientific reports, 2020, 12-17, Volume: 10, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; Arginine; Biomarkers; Cells, Cultured; Chromatography, Liquid; Drug Monitoring; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Heterogeneous Nuclear Ribonucleoprotein A1; Humans; Leukocytes, Mononuclear; Mass Spectrometry; Methylation; Mice; Molecular Targeted Therapy; Neoplasms; Protein-Arginine N-Methyltransferases; Repressor Proteins; Substrate Specificity

2020
ICG/l-Arginine Encapsulated PLGA Nanoparticle-Thermosensitive Hydrogel Hybrid Delivery System for Cascade Cancer Photodynamic-NO Therapy with Promoted Collagen Depletion in Tumor Tissues.
    Molecular pharmaceutics, 2021, 03-01, Volume: 18, Issue:3

    Topics: Animals; Arginine; Cell Line, Tumor; Cell Proliferation; Collagen; Drug Delivery Systems; Female; Hydrogels; Indocyanine Green; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Nitric Oxide; Photochemotherapy; Photosensitizing Agents; Phototherapy; Polyesters; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Microenvironment

2021
Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting.
    The Journal of biological chemistry, 2020, 12-18, Volume: 295, Issue:51

    Topics: Animals; Arginine; Cachexia; Female; Heterografts; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle Proteins; Neoplasms; omega-N-Methylarginine

2020
A Multifunctional Nanovaccine based on L-Arginine-Loaded Black Mesoporous Titania: Ultrasound-Triggered Synergistic Cancer Sonodynamic Therapy/Gas Therapy/Immunotherapy with Remarkably Enhanced Efficacy.
    Small (Weinheim an der Bergstrasse, Germany), 2021, Volume: 17, Issue:6

    Topics: Arginine; Humans; Immunotherapy; Neoplasms; Titanium

2021
Comprehensive characterization of protein-protein interactions perturbed by disease mutations.
    Nature genetics, 2021, Volume: 53, Issue:3

    Topics: Arachidonate 5-Lipoxygenase; Arginine; Computational Biology; Disease; Genome, Human; Histones; Humans; Mutation; Neoplasms; Pharmacogenomic Testing; Proprotein Convertase 9; Protein Interaction Maps; Receptors, LDL; Reproducibility of Results; rho Guanine Nucleotide Dissociation Inhibitor alpha; rhoA GTP-Binding Protein; Serine

2021
Effect of dapagliflozin and/or L-arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor-beta 1, autophagy, and apoptosis.
    Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:6

    Topics: Animals; Apoptosis; Arginine; Autophagy; Benzhydryl Compounds; Glucosides; Male; Mice; Neoplasms; Nitric Oxide; Transforming Growth Factor beta1; Transforming Growth Factors

2021
Targeting a neoantigen derived from a common
    Science (New York, N.Y.), 2021, 03-05, Volume: 371, Issue:6533

    Topics: Alleles; Animals; Antibodies, Bispecific; Antibodies, Neoplasm; Antigens, Neoplasm; Arginine; Chlorocebus aethiops; COS Cells; Female; HEK293 Cells; Histidine; HLA-A2 Antigen; Humans; Immunization, Passive; Jurkat Cells; Lymphocyte Activation; Mice, Inbred NOD; Mutation; Neoplasms; T-Lymphocytes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2021
Immunomodulation of Tumor Microenvironment by Arginine-Loaded Iron Oxide Nanoparticles for Gaseous Immunotherapy.
    ACS applied materials & interfaces, 2021, May-05, Volume: 13, Issue:17

    Topics: Acrylic Resins; Animals; Arginine; Gases; Humans; Immunotherapy; Macrophages; Magnetite Nanoparticles; Mice; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; Tumor Microenvironment; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays

2021
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation.
    Cell reports, 2021, 05-11, Volume: 35, Issue:6

    Topics: Animals; Arginine; Chromatin; Humans; Immune Evasion; Neoplasms; T-Lymphocytes

2021
Is there a link between the prevalence of cardiovascular disease, diabetes, kidney disease, chronic obstructive pulmonary disease and malignancies and the severity of COVID-19 within the BAME population?
    Clinical medicine (London, England), 2021, Volume: 21, Issue:Suppl 2

    Topics: Arginine; Cardiovascular Diseases; Comorbidity; COVID-19; Diabetes Mellitus; Humans; Kidney Diseases; Neoplasms; Prevalence; Pulmonary Disease, Chronic Obstructive; Risk Factors; SARS-CoV-2

2021
Improving selective targeting to cancer-associated fibroblasts by modifying liposomes with arginine based materials.
    Journal of drug targeting, 2022, Volume: 30, Issue:1

    Topics: Arginine; Cancer-Associated Fibroblasts; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Fluorescein; Liposomes; Neoplasms

2022
Bioreducible, arginine-rich polydisulfide-based siRNA nanocomplexes with excellent tumor penetration for efficient gene silencing.
    Biomaterials science, 2021, Jul-27, Volume: 9, Issue:15

    Topics: Arginine; Cell Line, Tumor; Gene Silencing; Humans; Neoplasms; RNA Interference; RNA, Small Interfering

2021
    BioMed research international, 2021, Volume: 2021

    Topics: Antineoplastic Agents; Arginine; Binding Sites; Cell Movement; Cell Proliferation; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Glyceric Acids; Humans; Ligands; Medicine, Chinese Traditional; Molecular Docking Simulation; Neoplasms; Phosphoglycerate Mutase; Protein Binding

2021
Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level.
    Biomolecules, 2017, 07-03, Volume: 7, Issue:3

    Topics: Amino Acid Substitution; Arginine; Cell Line, Tumor; Codon, Nonsense; Cysteine; Histidine; Humans; Neoplasms; Proteome; Tryptophan; Tumor Suppressor Protein p53

2017
The Horizon in Cardio-Oncology: "You Are Only as Good as Your Endothelium".
    Journal of the American College of Cardiology, 2017, 07-11, Volume: 70, Issue:2

    Topics: Arginine; Breast Neoplasms; Endothelium; Heart Diseases; Humans; Neoplasms; Nitric Oxide

2017
Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
    Science signaling, 2017, Nov-28, Volume: 10, Issue:507

    Topics: Animals; Arginine; Calcium; Cell Membrane; Drosophila melanogaster; Genomics; HCT116 Cells; HEK293 Cells; Humans; Ion Channel Gating; Molecular Dynamics Simulation; Muscular Diseases; Mutation; Neoplasm Proteins; Neoplasms; ORAI1 Protein; Patch-Clamp Techniques; Protein Structure, Secondary; Stromal Interaction Molecule 1; Transcriptional Activation

2017
Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.
    Journal for immunotherapy of cancer, 2017, 12-19, Volume: 5, Issue:1

    Topics: Animals; Arginase; Arginine; Cell Line, Tumor; Cell Proliferation; Female; Hep G2 Cells; Humans; K562 Cells; Male; Mice; Myeloid Cells; Neoplasms; Pyrrolidines; Small Molecule Libraries; T-Lymphocytes; Tumor Microenvironment; Up-Regulation; Xenograft Model Antitumor Assays

2017
Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies.
    Journal of theoretical biology, 2018, 04-07, Volume: 442

    Topics: Algorithms; Animals; Antineoplastic Agents; Arginine; Fluorouracil; Humans; Immune Tolerance; Immunity; Killer Cells, Natural; Lymphoma; Mice; Models, Immunological; Myeloid-Derived Suppressor Cells; Neoplasms; T-Lymphocytes, Cytotoxic

2018
Elevated mitochondrial SLC25A29 in cancer modulates metabolic status by increasing mitochondria-derived nitric oxide.
    Oncogene, 2018, Volume: 37, Issue:19

    Topics: Animals; Arginine; Carnitine Acyltransferases; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Glycolysis; HeLa Cells; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mitochondria; Mitochondrial Proteins; Neoplasm Transplantation; Neoplasms; Nitric Oxide; Up-Regulation

2018
Design and Development of Polysaccharide-Doxorubicin-Peptide Bioconjugates for Dual Synergistic Effects of Integrin-Targeted and Cell-Penetrating Peptides for Cancer Chemotherapy.
    Bioconjugate chemistry, 2018, 06-20, Volume: 29, Issue:6

    Topics: Animals; Antibiotics, Antineoplastic; Arginine; Carboxymethylcellulose Sodium; Cell Line, Tumor; Cell-Penetrating Peptides; Chickens; Doxorubicin; Drug Carriers; Drug Delivery Systems; HEK293 Cells; Humans; Integrins; Neoplasms; Oligopeptides

2018
Development of novel affinity reagents for detecting protein tyrosine phosphorylation based on superbinder SH2 domain in tumor cells.
    Analytica chimica acta, 2018, Nov-22, Volume: 1032

    Topics: Arginine; Cell Line, Tumor; Fluorescent Antibody Technique; Green Fluorescent Proteins; Humans; Immunoblotting; Microscopy, Fluorescence; Neoplasms; Optical Imaging; Phosphorylation; src Homology Domains; src-Family Kinases; Tyrosine

2018
Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide-Generating Agents Improves the Therapeutic Effects of Nanomedicines.
    Molecular cancer therapeutics, 2018, Volume: 17, Issue:12

    Topics: Animals; Antineoplastic Agents; Arginine; Disease Models, Animal; Doxorubicin; Female; Hydroxyurea; Macromolecular Substances; Male; Mice; Nanomedicine; Nanoparticles; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Permeability; Rats, Sprague-Dawley

2018
Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis.
    The Journal of biological chemistry, 2019, 01-04, Volume: 294, Issue:1

    Topics: Amino Acid Substitution; Arginine; Caspase 6; Humans; Hydrolysis; Mutation, Missense; Neoplasm Proteins; Neoplasms; Neurodegenerative Diseases; Protein Domains

2019
Autophagy maintains tumour growth through circulating arginine.
    Nature, 2018, Volume: 563, Issue:7732

    Topics: Allografts; Animals; Arginase; Arginine; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carcinogenesis; Cell Proliferation; Dietary Supplements; Hepatocytes; Liver; Male; Mice; Neoplasm Transplantation; Neoplasms; Ornithine

2018
Maintaining the tumour's diet.
    Nature reviews. Cancer, 2019, Volume: 19, Issue:2

    Topics: Arginine; Autophagy; Diet; Humans; Neoplasms

2019
Explosible nanocapsules excited by pulsed microwaves for efficient thermoacoustic-chemo combination therapy.
    Nanoscale, 2019, Jan-23, Volume: 11, Issue:4

    Topics: Animals; Arginine; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Liberation; Female; Humans; Hyperthermia, Induced; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microwaves; Nanocapsules; Neoplasms; Polymers; Skin; Survival Rate; Transplantation, Heterologous

2019
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.
    Nature communications, 2019, 01-22, Volume: 10, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; DNA; DNA Damage; DNA Polymerase II; DNA Repair Enzymes; DNA Replication; DNA-Directed DNA Polymerase; Genes, Fungal; Humans; Mutagenesis; Mutation; Mutation Rate; Neoplasms; Phenotype; Protein Domains; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2019
Host Control of Tumor Feeding: Autophagy Holds the Key.
    Cell metabolism, 2019, 02-05, Volume: 29, Issue:2

    Topics: Arginine; Autophagy; Humans; Neoplasms

2019
Blood Circulation-Prolonging Peptides for Engineered Nanoparticles Identified via Phage Display.
    Nano letters, 2019, 03-13, Volume: 19, Issue:3

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Bacteriophage M13; Biological Transport; Cell Surface Display Techniques; Doxorubicin; Ferritins; Glycine; Humans; Nanoparticles; Neoplasms; Peptide Library; Peptides

2019
Transport of cystine across xC
    Archives of biochemistry and biophysics, 2019, 03-30, Volume: 664

    Topics: Alanine; Amino Acid Substitution; Amino Acid Transport System y+; Antiporters; Arginine; Binding Sites; Cystine; Humans; Molecular Dynamics Simulation; Neoplasms; Protein Transport

2019
A Highly Effective π-π Stacking Strategy To Modify Black Phosphorus with Aromatic Molecules for Cancer Theranostics.
    ACS applied materials & interfaces, 2019, Mar-13, Volume: 11, Issue:10

    Topics: Arginine; Aspartic Acid; Glycine; Humans; Nanocomposites; Neoplasms; Peptides; Phosphorus; Phototherapy; Theranostic Nanomedicine

2019
A light-facilitated drug delivery system from a pseudo-protein/hyaluronic acid nanocomplex with improved anti-tumor effects.
    Nanoscale, 2019, May-28, Volume: 11, Issue:20

    Topics: Animals; Antineoplastic Agents; Arginine; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Endocytosis; Female; Humans; Hyaluronic Acid; Light; Mice; Mice, Nude; Nanostructures; Neoplasms; Peptides; Tissue Distribution

2019
Starvation in cancer cells: circulating arginine is good for cancer but bad for patients.
    Expert review of anticancer therapy, 2019, Volume: 19, Issue:6

    Topics: Animals; Antineoplastic Agents; Arginine; Autophagy; Humans; Neoplasms; Signal Transduction

2019
Arginine Starvation and Docetaxel Induce c-Myc-Driven hENT1 Surface Expression to Overcome Gemcitabine Resistance in ASS1-Negative Tumors.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 08-15, Volume: 25, Issue:16

    Topics: Animals; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Cell Membrane; Deoxycytidine; Disease Models, Animal; Docetaxel; Equilibrative Nucleoside Transporter 1; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Models, Biological; Neoplasms; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-myc; Xenograft Model Antitumor Assays

2019
Modulation of CAT-2B-Mediated l-Arginine Uptake and Nitric Oxide Biosynthesis in HCT116 Cell Line Through Biological Activity of 4'-Geranyloxyferulic Acid Extract from Quinoa Seeds.
    International journal of molecular sciences, 2019, Jul-02, Volume: 20, Issue:13

    Topics: Anticarcinogenic Agents; Arginine; Cationic Amino Acid Transporter 2; Chenopodium quinoa; Coumaric Acids; HCT116 Cells; Humans; Inflammation; Neoplasms; Nitric Oxide; Oxidative Stress; Seeds

2019
[Efficacy of AboundTM for hand-foot syndrome caused by capecitabine].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2013, Volume: 40, Issue:12

    Topics: Aged; Antimetabolites, Antineoplastic; Arginine; Butyrates; Capecitabine; Deoxycytidine; Female; Fluorouracil; Glutamine; Hand-Foot Syndrome; Humans; Hydroxy Acids; Male; Middle Aged; Neoplasms

2013
A preliminary report on the changes in the blood during malignancy, pregnancy, and injury.
    Permanente Foundation medical bulletin, 1951, Volume: 9, Issue:1

    Topics: Arginine; Blood Proteins; Female; Humans; Neoplasms; Pregnancy; Wounds and Injuries

1951
Enhanced arginine methylation of programmed cell death 4 protein during nutrient deprivation promotes tumor cell viability.
    The Journal of biological chemistry, 2014, Jun-20, Volume: 289, Issue:25

    Topics: Apoptosis Regulatory Proteins; Arginine; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasm Proteins; Neoplasms; Phosphorylation; Protein-Arginine N-Methyltransferases; RNA-Binding Proteins; Up-Regulation

2014
Evolution of histone 2A for chromatin compaction in eukaryotes.
    eLife, 2014, Jun-17, Volume: 3

    Topics: Animals; Arginine; Cell Line, Tumor; Chromatin; Chromatin Assembly and Disassembly; Evolution, Molecular; Genome, Fungal; HEK293 Cells; Histones; Humans; Neoplasms; Nucleosomes; Protein Structure, Tertiary; Saccharomyces cerevisiae; Xenopus laevis

2014
[Plasma amino acid profiling of "same symptom for different disease" in Uyghur medicine based on high-performance liquid chromatography].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2014, Volume: 39, Issue:6

    Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Cystine; Humans; Isoleucine; Leucine; Medicine, Chinese Traditional; Neoplasms; Serine; Tyrosine; Valine

2014
Pollution linked to lethal sea turtle tumours.
    Marine pollution bulletin, 2014, Nov-15, Volume: 88, Issue:1-2

    Topics: Animals; Arginine; Conservation of Natural Resources; Endangered Species; Environmental Exposure; Hawaii; Neoplasms; Rhodophyta; Turtles; Water Pollutants, Chemical

2014
Arginine depletion by arginine deiminase does not affect whole protein metabolism or muscle fractional protein synthesis rate in mice.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Animals; Arginine; Hydrolases; Male; Mice; Mice, Inbred ICR; Muscle Proteins; Muscle, Skeletal; Neoplasms; Polyethylene Glycols

2015
Evolving paradigms in the nutritional support of critically ill surgical patients.
    Current problems in surgery, 2015, Volume: 52, Issue:4

    Topics: Arginine; Burns; Cachexia; Critical Illness; Enteral Nutrition; Fish Oils; Gastrointestinal Tract; Glutamine; Humans; Infusions, Intravenous; Lipids; Microbiota; Multiple Organ Failure; Muscle, Skeletal; Neoplasms; Parenteral Nutrition; Perioperative Care; Protein-Energy Malnutrition; Stress, Physiological

2015
p53-Encoding pDNA Purification by Affinity Chromatography for Cancer Therapy.
    Methods in molecular biology (Clifton, N.J.), 2015, Volume: 1317

    Topics: Alkalies; Animals; Arginine; Blotting, Western; Chlorocebus aethiops; Chromatography, Affinity; COS Cells; DNA; Electrophoresis, Agar Gel; Neoplasms; Plasmids; Tumor Suppressor Protein p53

2015
Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents.
    Oncogene, 2016, Mar-31, Volume: 35, Issue:13

    Topics: Antineoplastic Agents; Arginine; Axl Receptor Tyrosine Kinase; Cell Death; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Hydrolases; Intercellular Signaling Peptides and Proteins; Molecular Targeted Therapy; Neoplasms; Polyethylene Glycols; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction

2016
Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Jul-07, Volume: 112, Issue:27

    Topics: Alternative Splicing; Animals; Arginine; Binding Sites; Biomechanical Phenomena; Blotting, Western; Cattle; Cells, Cultured; Endothelial Cells; Extracellular Matrix; Fibronectins; Humans; Mice; Microscopy, Confocal; Neoplasms; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Protein Isoforms; Proto-Oncogene Proteins c-akt; rho-Associated Kinases; RNA Interference; Serine; Signal Transduction; Tumor Microenvironment; Vascular Endothelial Growth Factor A

2015
Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Arginine; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Drug Carriers; Female; Fluorescein-5-isothiocyanate; Folic Acid; Glutamic Acid; HEK293 Cells; Humans; Lethal Dose 50; Male; Mice; Mice, Nude; Molecular Weight; Neoplasms; Paclitaxel; Prodrugs; Solubility; Toxicity Tests, Acute; Xenograft Model Antitumor Assays

2015
Twin-Arginine Translocation Peptide Conjugated Epirubicin-Loaded Nanoparticles for Enhanced Tumor Penetrating and Targeting.
    Journal of pharmaceutical sciences, 2015, Volume: 104, Issue:12

    Topics: Animals; Arginine; Cell Line, Tumor; Cell-Penetrating Peptides; Drug Carriers; Drug Delivery Systems; Epirubicin; Humans; Mice; Nanoparticles; Neoplasms; Rats; Tissue Distribution; Twin-Arginine-Translocation System

2015
PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.
    Oncotarget, 2015, Nov-03, Volume: 6, Issue:34

    Topics: Amino Acid Sequence; Arginine; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; HEK293 Cells; HeLa Cells; Humans; Methylation; Mitosis; Molecular Sequence Data; Neoplasms; Protein-Arginine N-Methyltransferases; Repressor Proteins; Transfection

2015
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.
    Journal of the American Chemical Society, 2016, Jan-27, Volume: 138, Issue:3

    Topics: Arginine; Epigenesis, Genetic; HEK293 Cells; Humans; Isocitrate Dehydrogenase; Models, Molecular; Molecular Structure; Mutant Proteins; Mutation; Neoplasms; Photochemical Processes

2016
Mono-arginine Cholesterol-based Small Lipid Nanoparticles as a Systemic siRNA Delivery Platform for Effective Cancer Therapy.
    Theranostics, 2016, Volume: 6, Issue:2

    Topics: Animals; Arginine; Cell Line, Tumor; Cholesterol; Female; Genetic Therapy; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; RNA, Small Interfering

2016
Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).
    Scientific reports, 2016, Mar-14, Volume: 6

    Topics: Animals; Arginine; Argininosuccinate Synthase; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; HCT116 Cells; Humans; Hydrolases; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mechanistic Target of Rapamycin Complex 1; Mice, SCID; Multiprotein Complexes; Neoplasms; Nitric Oxide; Nitric Oxide Synthase Type II; Perfusion; Polyethylene Glycols; TOR Serine-Threonine Kinases; Tumor Burden; Unfolded Protein Response; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2016
Combined factor IIa and Xa inhibitor therapy for thrombosis whilst on therapeutic anticoagulant.
    Thrombosis research, 2016, Volume: 143

    Topics: Adult; Aged; Anticoagulants; Antithrombins; Arginine; Dabigatran; Factor Xa Inhibitors; Female; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Neoplasms; Pipecolic Acids; Pyrazoles; Pyridones; Recurrence; Rivaroxaban; Sulfonamides; Venous Thrombosis

2016
Development of hematin conjugated PLGA nanoparticle for selective cancer targeting.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Aug-25, Volume: 91

    Topics: Arginine; Drug Delivery Systems; HeLa Cells; Hemin; Humans; Lactic Acid; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proton-Coupled Folate Transporter; Surface Properties

2016
A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.
    Oncogene, 2017, 01-19, Volume: 36, Issue:3

    Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenocarcinoma of Lung; Arginine; Breast Neoplasms; Carcinoma, Squamous Cell; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; MCF-7 Cells; Methylation; Neoplasm Invasiveness; Neoplasms; Prognosis; Protein-Arginine N-Methyltransferases; Sequence Analysis, RNA; Transcription, Genetic; Transforming Growth Factor beta

2017
Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation.
    Oncotarget, 2016, Dec-13, Volume: 7, Issue:50

    Topics: Antineoplastic Combined Chemotherapy Protocols; Arginine; Argininosuccinate Synthase; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cell Survival; Cisplatin; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Homeodomain Proteins; Humans; Hydrolases; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Polyethylene Glycols; Promoter Regions, Genetic; Proteasome Inhibitors; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; Time Factors; Transcription, Genetic; Transfection

2016
Metabolism-Centric Trans-Omics.
    Cell systems, 2017, 01-25, Volume: 4, Issue:1

    Topics: Arginine; Humans; Neoplasms; T-Lymphocytes

2017
Construction and in vitro evaluation of enzyme nanoreactors based on carboxymethyl chitosan for arginine deprivation in cancer therapy.
    Carbohydrate polymers, 2017, Apr-15, Volume: 162

    Topics: Arginine; Chitosan; Enzymes; Hydrolases; Micelles; Nanotechnology; Neoplasms

2017
High gene delivery in tumor by intratumoral injection of tetraarginine-PEG lipid-coated protamine/DNA.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, Jul-14, Volume: 129, Issue:2

    Topics: Animals; Arginine; DNA; Female; Genetic Therapy; HeLa Cells; Humans; Injections, Intralesional; Lipids; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides; Particle Size; Polyethylene Glycols; Protamines; Transfection; Xenograft Model Antitumor Assays

2008
Some aspects of the role of arginine and arginase in mouse carcinoma 63.
    Enzymologia, 1947, Volume: 12, Issue:3

    Topics: Animals; Arginase; Arginine; Humans; Mice; Neoplasms

1947
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells.
    The FEBS journal, 2008, Volume: 275, Issue:23

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Amidinotransferases; Animals; Arginase; Arginine; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Creatine; Creatinine; Enzymes; Female; Gene Expression Regulation, Neoplastic; Guanidinoacetate N-Methyltransferase; Kidney; Liver; Membrane Transport Proteins; Methionine; Mice; Muscle, Skeletal; Neoplasms; Ornithine; Ornithine Decarboxylase; Sarcoma 180

2008
Modulators of arginine metabolism support cancer immunosurveillance.
    BMC immunology, 2009, Jan-09, Volume: 10

    Topics: Animals; Arginine; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Immunologic Factors; Immunologic Surveillance; Interferon-gamma; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells; Myelopoiesis; Neoplasms; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Spleen; Weight Loss

2009
p53 methylation--the Arg-ument is clear.
    Cell cycle (Georgetown, Tex.), 2009, Mar-15, Volume: 8, Issue:6

    Topics: Animals; Arginine; DNA Damage; Humans; Methylation; Neoplasms; Phosphorylation; Protein Methyltransferases; Protein Processing, Post-Translational; Tumor Suppressor Protein p53

2009
Effects of L-arginine and L-lysine mixtures on splenic sympathetic nerve activity and tumor proliferation.
    Autonomic neuroscience : basic & clinical, 2009, May-11, Volume: 147, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arginine; Carcinoma; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Female; Humans; Immune Tolerance; Immunologic Factors; Killer Cells, Natural; Lysine; Male; Mice; Mice, Inbred BALB C; Neoplasms; Neuroimmunomodulation; Rats; Rats, Wistar; Spleen; Sympathetic Nervous System; Treatment Outcome

2009
Enteral administration of alanyl-[2-(15)N]glutamine contributes more to the de novo synthesis of arginine than does intravenous infusion of the dipeptide in humans.
    The American journal of clinical nutrition, 2009, Volume: 90, Issue:1

    Topics: Arginine; Body Mass Index; Citrulline; Dipeptides; Enteral Nutrition; Female; Gastrointestinal Diseases; Glutamine; Humans; Infusions, Intravenous; Isotope Labeling; Male; Middle Aged; Neoplasms; Nitrogen Isotopes

2009
Constructing bioactive peptides with pH-dependent activities.
    Peptides, 2009, Volume: 30, Issue:8

    Topics: Amino Acid Sequence; Animals; Arginine; Cell Death; Cell Line; Fluoresceins; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Mice; Mice, Nude; Micelles; Neoplasms; Peptides; Structure-Activity Relationship; Transplantation, Homologous

2009
Arginine methylation regulates telomere length and stability.
    Molecular and cellular biology, 2009, Volume: 29, Issue:18

    Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Cell Line; Cell Proliferation; Cellular Senescence; Chromatin Immunoprecipitation; Humans; Methylation; Molecular Sequence Data; Neoplasms; Protein Binding; Protein Structure, Tertiary; Protein-Arginine N-Methyltransferases; Repressor Proteins; Structure-Activity Relationship; Telomere; Telomeric Repeat Binding Protein 2

2009
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
    Journal of cancer research and clinical oncology, 2010, Volume: 136, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors

2010
The effect of surface modification of adenovirus with an arginine-grafted bioreducible polymer on transduction efficiency and immunogenicity in cancer gene therapy.
    Biomaterials, 2010, Volume: 31, Issue:7

    Topics: Adenoviridae; Animals; Arginine; Cations; Cell Death; Cell Line; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Genetic Therapy; Humans; Immune Evasion; Light; Mice; Neoplasms; Polyamines; Polyethyleneimine; Receptors, Virus; Reproducibility of Results; Scattering, Radiation; Serum; Surface Properties; Transduction, Genetic

2010
RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, May-10, Volume: 143, Issue:3

    Topics: Animals; Arginine; Chlorocebus aethiops; COS Cells; Genes, erbB-2; Genetic Therapy; Mice; Mice, Inbred BALB C; Neoplasms; Peptides; RNA Interference; RNA, Small Interfering

2010
Arginine-arginase relationship in regeneration, repair and development of neoplasms.
    Journal of dental research, 1946, Volume: 25, Issue:6

    Topics: Arginase; Arginine; Humans; Neoplasms; Regeneration; Wound Healing

1946
Some aspects of the metabolism of arginine in malignant tissue.
    The Biochemical journal, 1946, Volume: 40, Issue:4

    Topics: Arginine; Neoplasms

1946
Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
    International journal of cancer, 2011, Feb-01, Volume: 128, Issue:3

    Topics: Anthracenes; Arginine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line, Tumor; DNA Replication; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasms; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Propane; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA, Small Interfering; Urinary Bladder Neoplasms

2011
Simultaneous determination of l-citrulline and l-arginine in plasma by high performance liquid chromatography.
    Clinical biochemistry, 2010, Volume: 43, Issue:13-14

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Indicators and Reagents; Limit of Detection; Male; Methods; Middle Aged; Neoplasms

2010
Induction of apoptosis by gene transfer of human TRAIL mediated by arginine-rich intracellular delivery peptides.
    Anticancer research, 2010, Volume: 30, Issue:6

    Topics: Apoptosis; Arginine; Cell Line, Tumor; Drug Delivery Systems; Flow Cytometry; Genetic Therapy; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Neoplasms; Peptides; Plasmids; TNF-Related Apoptosis-Inducing Ligand

2010
Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes.
    Cell biology international, 2010, Volume: 34, Issue:11

    Topics: Arginase; Arginine; Argininosuccinate Synthase; Citrulline; Epithelial Cells; Humans; Neoplasms; Ornithine; Ornithine Carbamoyltransferase; Tumor Cells, Cultured

2010
Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells.
    Anti-cancer drugs, 2011, Volume: 22, Issue:2

    Topics: Apoptosis; Arginine; Canavanine; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Drug Therapy, Combination; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Neoplasms; Protein Binding

2011
Enzymatic hydrolysis of benzoylarginineamide in normal and neoplastic tissues.
    Journal of the National Cancer Institute, 1946, Volume: 6

    Topics: Arginine; Enzymes; Hydrolysis; Neoplasms

1946
Immunohistochemical detection of arginine methylated proteins (MeRP) in archival tissues.
    Histopathology, 2010, Volume: 57, Issue:5

    Topics: Antibodies; Antibody Specificity; Arginine; Immunohistochemistry; Methylation; Neoplasms; Paraffin Embedding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins

2010
Rapid evolution of arginine deiminase for improved anti-tumor activity.
    Applied microbiology and biotechnology, 2011, Volume: 90, Issue:1

    Topics: Amino Acid Sequence; Antineoplastic Agents; Arginine; Bacterial Proteins; Directed Molecular Evolution; Enzyme Stability; Hydrolases; Kinetics; Models, Molecular; Molecular Sequence Data; Neoplasms; Pseudomonas; Sequence Alignment

2011
Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex.
    Nanomedicine : nanotechnology, biology, and medicine, 2011, Volume: 7, Issue:5

    Topics: Animals; Arginine; beta-Galactosidase; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Therapy; Humans; Leucine; Lysine; Mice; Mice, Inbred BALB C; Neoplasms; Polyethyleneimine

2011
Roles of protein arginine methylation in DNA damage signaling pathways is CARM1 a life-or-death decision point?
    Cell cycle (Georgetown, Tex.), 2011, May-01, Volume: 10, Issue:9

    Topics: Arginine; Cell Survival; DNA Damage; DNA Methylation; Humans; Neoplasms; Protein-Arginine N-Methyltransferases; Signal Transduction

2011
RNA interference of argininosuccinate synthetase restores sensitivity to recombinant arginine deiminase (rADI) in resistant cancer cells.
    Journal of biomedical science, 2011, Apr-01, Volume: 18

    Topics: Antineoplastic Agents; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Cell Survival; Citrulline; Drug Resistance, Neoplasm; Gene Expression; HeLa Cells; Humans; Hydrolases; Neoplasms; Recombinant Proteins; RNA Interference; RNA, Small Interfering

2011
FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development.
    The Journal of pathology, 2011, Volume: 224, Issue:2

    Topics: Abnormalities, Multiple; Alleles; Amino Acid Sequence; Animals; Arginine; Cell Cycle Proteins; Disease Models, Animal; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Humans; Lung; Mice; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Point Mutation; Pulmonary Alveoli; Sequence Alignment; Transforming Growth Factor beta; Ubiquitin-Protein Ligases

2011
Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex.
    Biomaterials, 2011, Volume: 32, Issue:25

    Topics: Animals; Arginine; Female; Gene Expression; Humans; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Neoplasms; Polypropylenes

2011
Differences in DNA condensation and release by lysine and arginine homopeptides govern their DNA delivery efficiencies.
    Molecular pharmaceutics, 2011, Oct-03, Volume: 8, Issue:5

    Topics: Animals; Arginine; Biological Transport; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Packaging; DNA-Binding Proteins; DNA, Neoplasm; DNA, Viral; Gene Transfer Techniques; Genetic Vectors; Humans; Lysine; Molecular Weight; Neoplasms; Nucleic Acid Conformation; Oligopeptides; Particle Size; Peptides; Structure-Activity Relationship

2011
Distinct transduction modes of arginine-rich cell-penetrating peptides for cargo delivery into tumor cells.
    International journal of pharmaceutics, 2011, Oct-31, Volume: 419, Issue:1-2

    Topics: Animals; Arginine; Avidin; Biological Transport; Cell Line, Tumor; Cell Membrane; Cell-Penetrating Peptides; Drug Delivery Systems; Endocytosis; Fluorescein-5-isothiocyanate; Heparan Sulfate Proteoglycans; Humans; Mice; Molecular Weight; Neoplasms; Rats; Temperature; Time Factors

2011
Arginine residues are more effective than lysine residues in eliciting the cellular uptake of onconase.
    Biochemistry, 2011, Nov-29, Volume: 50, Issue:47

    Topics: Amphibian Proteins; Animals; Antineoplastic Agents; Arginine; Humans; K562 Cells; Lysine; Models, Molecular; Neoplasms; Rana pipiens; Ribonucleases

2011
Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2012, Feb-28, Volume: 158, Issue:1

    Topics: Animals; Arginase; Arginine; Cysteine; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Polyethylene Glycols

2012
Photodynamic anticancer activities of water-soluble C(60) derivatives and their biological consequences in a HeLa cell line.
    Chemico-biological interactions, 2012, Jan-05, Volume: 195, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Arginine; Caspase 3; Catalase; Cell Survival; Folic Acid; Fullerenes; Glutathione Peroxidase; HeLa Cells; Humans; Light; Malondialdehyde; Membrane Potential, Mitochondrial; Neoplasms; Phenylalanine; Photochemotherapy; Reactive Oxygen Species; Superoxide Dismutase; Water

2012
An arginine derivative contained nanostructure lipid carriers with pH-sensitive membranolytic capability for lysosomolytic anti-cancer drug delivery.
    International journal of pharmaceutics, 2012, Oct-15, Volume: 436, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arginine; Cell Line, Tumor; Cell Membrane; Cell Survival; Cells, Cultured; Drug Carriers; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; Lipids; Lysosomes; Male; Mice; Nanoparticles; Neoplasms; Paclitaxel; Rats; Serum Albumin, Bovine; Tissue Distribution

2012
T-ARG-eting E2F-1 growth control.
    Cell cycle (Georgetown, Tex.), 2012, Aug-15, Volume: 11, Issue:16

    Topics: Animals; Apoptosis; Arginine; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Methylation; Mice; Neoplasms; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Tumor Suppressor Protein p53; Ubiquitination

2012
The key role of IL-6-arginase cascade for inducing dendritic cell-dependent CD4(+) T cell dysfunction in tumor-bearing mice.
    Journal of immunology (Baltimore, Md. : 1950), 2013, Jan-15, Volume: 190, Issue:2

    Topics: Animals; Arginase; Arginine; CD4-Positive T-Lymphocytes; Dendritic Cells; Female; Histocompatibility Antigens Class II; Interleukin-6; Lymphocyte Activation; Mice; Mice, Transgenic; Neoplasms; Signal Transduction

2013
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential.
    Nature genetics, 2003, Volume: 33, Issue:3

    Topics: Apoptosis; Arginine; Cell Line; Chaperonin 60; Codon; Fatty Acids, Unsaturated; Genes, p53; Genetic Variation; HSP70 Heat-Shock Proteins; Humans; Membrane Proteins; Mitochondria; Neoplasms; Polymorphism, Genetic; Proline; Suppression, Genetic; Transcriptional Activation; Tumor Suppressor Protein p53; Ubiquitin

2003
Basic peptide system for efficient delivery of foreign genes.
    Biochimica et biophysica acta, 2003, May-12, Volume: 1640, Issue:2-3

    Topics: Animals; Arginine; Biological Transport; Cell Line; DNA; Genetic Therapy; Humans; Neoplasms; Peptides; Proteoglycans; Thymidine Kinase; Transfection

2003
Oncogenic mutations and packing defects in protein structure.
    Journal of biomolecular structure & dynamics, 2003, Volume: 21, Issue:1

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Glycine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Mutation; Neoplasms; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins p21(ras); Static Electricity; Tumor Suppressor Protein p53; Valine

2003
The competitive effect of canavanine on utilization of arginine in growth of Walker carcinosarcoma 256 cells in vitro.
    Cancer research, 1958, Volume: 18, Issue:3

    Topics: Amino Acids; Animals; Arginine; Canavanine; Carcinoma 256, Walker; In Vitro Techniques; Neoplasms

1958
Effects of certain amino acid derivatives on microorganisms and sarcoma 180.
    Journal of the National Cancer Institute, 1958, Volume: 20, Issue:3

    Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Lactobacillus; Neoplasms; Sarcoma 180

1958
Arginine uptake and arginase activity in Ehrlich ascites carcinoma cells.
    Canadian journal of biochemistry and physiology, 1959, Volume: 37, Issue:4

    Topics: Amidohydrolases; Arginase; Arginine; Ascites; Biochemical Phenomena; Carbohydrate Metabolism; Carbohydrates; Catabolite Repression; Glucose; Humans; Neoplasms

1959
[Free arginine in tumors and tumor-bearing animals].
    Voprosy onkologii, 1959, Volume: 5, Issue:2

    Topics: Animals; Arginine; Neoplasms; Neoplasms, Experimental

1959
Suppression of uptake of L-arginine-U-14C into chromatographically separated cationic nuclear proteins of tissues of tumour-bearing rats by 5-bis (2-chloroethyl) aminouracil.
    Biochemical pharmacology, 1961, Volume: 6

    Topics: Animals; Arginine; Biochemical Phenomena; Cations; Neoplasms; Nuclear Proteins; Nucleoproteins; Rats; Uracil

1961
Kinetics of incorporation of L-arginine-U-C14 into nuclear proteins of tumors and other tissues in vitro.
    Cancer research, 1960, Volume: 20

    Topics: Arginine; Histones; In Vitro Techniques; Kinetics; Neoplasms; Nuclear Proteins; Nucleoproteins

1960
[CLINICAL AND EXPERIMENTAL STUDIES ON CHANGES IN THE BODY FLUIDS IN CANCER].
    [Nisshin igaku] The Japanese journal of medical progress, 1963, Volume: 50

    Topics: Antineoplastic Agents; Arginine; Ascites; Aspartate Aminotransferases; Blood Chemical Analysis; Blood Proteins; Body Fluids; Cyclophosphamide; Glycoproteins; Mechlorethamine; Mitomycin; Mitomycins; Neoplasms; Neuraminic Acids; Pharmacology; Polarography; Rats; Research; Thiotepa

1963
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Nov-04, Volume: 257

    Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine

1963
TRANSAMIDINASE ACTIVITIES IN VITRO OF KIDNEYS FROM TUMOR-BEARING MICE AND RATS FED DIETS SUPPLEMENTED WITH PROTEIN OR CERTAIN AMINO ACIDS.
    Cancer research, 1964, Volume: 24

    Topics: Amidinotransferases; Amino Acids; Animals; Arginine; Blood Chemical Analysis; Carcinoma 256, Walker; Creatine; Creatinine; Diet; Dietary Proteins; Dietary Supplements; Glycine; In Vitro Techniques; Kidney; Mice; Neoplasms; Neoplasms, Experimental; Proteins; Rats; Research; Transferases; Urine

1964
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
    Proceedings of the National Academy of Sciences of the United States of America, 1964, Volume: 51

    Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research

1964
[ROLE OF THE ARGININE-ARGINASE COMPLEX IN NORMAL AND ABNORMAL TISSUE GROWTH].
    Anales de la Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay, 1963, Volume: 48

    Topics: Arginase; Arginine; Growth; Humans; Neoplasms; Ornithine; Physiological Phenomena; Proteins; Ultraviolet Rays

1963
CYTOPATHOGENIC MYCOPLASMAS ASSOCIATED WITH TWO HUMAN TUMORS. I. ISOLATION AND BIOLOGICAL ASPECTS.
    Journal of bacteriology, 1965, Volume: 90

    Topics: Animals; Arginine; Culture Media; Fibroma; Hemangioma; Humans; Microbiology; Mycoplasma; Neoplasms; Neutralization Tests; Pharyngeal Neoplasms; Research; Tissue Culture Techniques; Vesicular Stomatitis; Vesicular stomatitis Indiana virus; Viral Interference

1965
Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: a method for identifying cancers sensitive to arginine deprivation.
    Cancer, 2004, Feb-15, Volume: 100, Issue:4

    Topics: Arginine; Argininosuccinate Synthase; Biopsy; Citrullinemia; Humans; Immunohistochemistry; Neoplasms; Pharmacogenetics; Tumor Cells, Cultured

2004
Arg9-peptide facilitates the internalization of an anti-CEA immunotoxin and potentiates its specific cytotoxicity to target cells.
    The international journal of biochemistry & cell biology, 2005, Volume: 37, Issue:1

    Topics: Arginine; Carcinoembryonic Antigen; Cell Line, Tumor; Cytotoxicity, Immunologic; Endocytosis; Humans; Immunotoxins; Neoplasms; Oligopeptides; Protein Transport; Recombinant Fusion Proteins

2005
Arginine methylation of STAT1: a reassessment.
    Cell, 2004, Nov-24, Volume: 119, Issue:5

    Topics: Arginine; Artifacts; DNA-Binding Proteins; Humans; Interferons; Methylation; Methyltransferases; Mutation; Neoplasms; Reproducibility of Results; STAT1 Transcription Factor; Trans-Activators

2004
Plasma arginine concentrations are reduced in cancer patients: evidence for arginine deficiency?
    The American journal of clinical nutrition, 2005, Volume: 81, Issue:5

    Topics: Adult; Aged; Arginine; Breast Neoplasms; Case-Control Studies; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Neoplasms; Pancreatic Neoplasms; Weight Loss

2005
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
    Cell cycle (Georgetown, Tex.), 2005, Volume: 4, Issue:9

    Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; beta-Galactosidase; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Separation; Cells, Cultured; Chromatin Immunoprecipitation; Codon; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Flow Cytometry; Homozygote; Humans; Luciferases; Microscopy, Fluorescence; Neoplasms; Oligonucleotides; Oxidative Stress; Polymorphism, Genetic; Proline; Propidium; Protein Isoforms; Transfection

2005
Integrity and stability of the citrulline-arginine pathway in normal and tumour cell lines.
    Cancer letters, 2005, Sep-28, Volume: 227, Issue:2

    Topics: Animals; Arginine; Argininosuccinic Acid; Carbon Radioisotopes; Cell Division; Cells, Cultured; Citrulline; Cricetinae; Dogs; Humans; Mice; Neoplasms; Rats; Signal Transduction

2005
Modulation of arginine metabolic pathways as the potential anti-tumor mechanism of recombinant arginine deiminase.
    Cancer letters, 2006, Jan-08, Volume: 231, Issue:1

    Topics: Adenocarcinoma; Arginine; Breast Neoplasms; Humans; Hydrolases; Lung Neoplasms; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Protein Biosynthesis; Tumor Cells, Cultured

2006
PMS2 mutations in childhood cancer.
    Journal of the National Cancer Institute, 2006, Mar-01, Volume: 98, Issue:5

    Topics: Adenosine Triphosphatases; Adolescent; Arginine; Astrocytoma; Cafe-au-Lait Spots; Child; Colonic Polyps; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Female; Founder Effect; Genetic Predisposition to Disease; Glioma; Humans; Leukemia, T-Cell; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Mismatch Repair Endonuclease PMS2; Mutation; Neoplasms; Neoplasms, Second Primary; Pakistan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; United Kingdom

2006
Mutational analysis of the p53 core domain L1 loop.
    The Journal of biological chemistry, 2006, Jul-21, Volume: 281, Issue:29

    Topics: Alanine; Amino Acid Substitution; Arginine; Base Sequence; Binding Sites; DNA; DNA Mutational Analysis; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation, Missense; Neoplasms; Nucleic Acid Conformation; Point Mutation; Protein Conformation; Protein Structure, Secondary; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53

2006
L-arginine availability regulates T-lymphocyte cell-cycle progression.
    Blood, 2007, Feb-15, Volume: 109, Issue:4

    Topics: Animals; Arginine; Cell Cycle; Cell Proliferation; Clonal Anergy; Cyclin D3; Cyclin-Dependent Kinases; Cyclins; Gene Expression Regulation; Humans; Mice; Mice, Knockout; Neoplasms; Protein Serine-Threonine Kinases; T-Lymphocytes

2007
Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene oxide)-b-poly(epsilon-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells.
    Biomacromolecules, 2007, Volume: 8, Issue:3

    Topics: Aldehydes; Arginine; Aspartic Acid; Cell Line, Tumor; Drug Delivery Systems; Glycine; Humans; Lactones; Micelles; Microscopy, Confocal; Microscopy, Fluorescence; Models, Chemical; Neoplasm Metastasis; Neoplasms; Peptides; Polyethylene Glycols

2007
Polymorphism of dihydropyrimidine dehydrogenase (DPYD) Cys29Arg and risk of six malignancies in Japanese.
    Nagoya journal of medical science, 2005, Volume: 67, Issue:3-4

    Topics: Adult; Aged; Aged, 80 and over; Arginine; Asian People; Chi-Square Distribution; Cysteine; Dihydrouracil Dehydrogenase (NADP); Female; Gene Frequency; Genotype; Humans; Japan; Male; Middle Aged; Models, Biological; Neoplasms; Odds Ratio; Polymorphism, Genetic

2005
TP53 codon 72 polymorphism in 12 populations of insular Southeast Asia and Oceania.
    Journal of human genetics, 2007, Volume: 52, Issue:8

    Topics: Amino Acid Substitution; Arginine; Asia, Southeastern; Codon; Gene Frequency; Genetic Predisposition to Disease; Humans; Neoplasms; Oceania; Polymorphism, Genetic; Population; Proline; Tumor Suppressor Protein p53

2007
Cancer immunology. Cancer's bulwark against immune attack: MDS cells.
    Science (New York, N.Y.), 2008, Jan-11, Volume: 319, Issue:5860

    Topics: Animals; Arginine; B-Lymphocytes; Cancer Vaccines; Cyclooxygenase 2; Humans; Immune Tolerance; Inflammation; Interleukin-1beta; Macrophages; Myeloid Cells; Neoplasms; Peroxynitrous Acid; Receptors, Antigen, T-Cell; T-Lymphocytes; Vascular Endothelial Growth Factor A

2008
Inhibition of osteopontin dependent carcinogenesis.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:8

    Topics: Alkaloids; Antineoplastic Agents; Arginine; Humans; Neoplasms; Osteopontin; Oxazolidinones; Pipecolic Acids; Selenium; Sulfonamides

2008
Aminoaciduria resulting from cycloleucine administration in man.
    Science (New York, N.Y.), 1967, Jul-28, Volume: 157, Issue:3787

    Topics: Amino Acids; Arginine; Cystinuria; Humans; Kidney Tubules; Lysine; Neoplasms; Ornithine

1967
Antitumor therapy based on the use of an immune modulator, arginine butyrate and interferon.
    Medical oncology and tumor pharmacotherapy, 1984, Volume: 1, Issue:2

    Topics: Amniotic Fluid; Animals; Arginine; Butyrates; Cytoskeleton; Extracellular Matrix; Female; Humans; Immune System; Interferons; Mice; Mice, Inbred AKR; Neoplasms; Pregnancy; Propionibacterium acnes; Rats; Sarcoma 180

1984
Plasma somatostatin in normal subjects and in various diseases: increased levels in somatostatin-producing tumors.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1982, Volume: 14, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Aged; Arginine; Calcitonin; Carcinoma; Diabetes Mellitus; Female; Humans; Liver Diseases; Male; Middle Aged; Neoplasms; Pheochromocytoma; Somatostatin; Thyroid Neoplasms

1982
[Studies on platelet aggregation induced by human cultured carcinoma cell lines].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:3

    Topics: Arginine; Cell Line; Cells, Cultured; Female; Humans; Lung Neoplasms; Membrane Proteins; Microbial Collagenase; Neoplasms; Neoplastic Cells, Circulating; Neuraminidase; Pipecolic Acids; Platelet Aggregation; Stomach Neoplasms; Sulfonamides; Trypsin

1984
Enzyme therapy: problems and solutions.
    Annual review of biochemistry, 1982, Volume: 51

    Topics: Animals; Arginine; Blood Coagulation Disorders; Enzyme Therapy; Enzymes; Enzymes, Immobilized; Erwinia; Escherichia coli; Fabry Disease; Folic Acid; gamma-Glutamyl Hydrolase; Gaucher Disease; Humans; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Metabolic Clearance Rate; Neoplasms; Poisoning; Ribonucleases; Urokinase-Type Plasminogen Activator

1982
Nutritional pharmacology: effects of L-arginine on host defences, response to trauma and tumour growth.
    Clinical science (London, England : 1979), 1994, Volume: 86, Issue:2

    Topics: Animals; Arginine; Cytotoxicity, Immunologic; Hemodynamics; Humans; Immune System; Immunity, Cellular; Macrophages; Neoplasms; Wound Healing

1994
Screening for germ line p53 mutations in children with malignant tumors and a family history of cancer.
    Cancer research, 1993, Feb-01, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Alleles; Arginine; Base Sequence; Child; Child, Preschool; Exons; Family Health; Female; Genes, p53; Germ Cells; Glycine; Humans; Infant; Li-Fraumeni Syndrome; Male; Middle Aged; Molecular Sequence Data; Mutation; Neoplasms; Pedigree; Sarcoma

1993
Should cancer patients with incurable disease receive parenteral or enteral nutritional support?
    European journal of cancer (Oxford, England : 1990), 1998, Volume: 34, Issue:3

    Topics: Arginine; Decision Making; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Parenteral Nutrition; Prognosis; Quality of Life; Terminal Care

1998
DNA sequence variants of p53: cancer and aging.
    American journal of human genetics, 1999, Volume: 65, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Codon; Genes, p53; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Middle Aged; Neoplasms; Odds Ratio; Polymorphism, Genetic; Proline

1999
Single amino acid (arginine) deprivation: rapid and selective death of cultured transformed and malignant cells.
    British journal of cancer, 2000, Volume: 83, Issue:6

    Topics: Animals; Apoptosis; Arginine; Cell Cycle; Cell Line, Transformed; Culture Media; Dipodomys; Flow Cytometry; Humans; Mice; Mink; Neoplasms; Tumor Cells, Cultured

2000
Inactivate the remaining p53 allele or the alternate p73? Preferential selection of the Arg72 polymorphism in cancers with recessive p53 mutants but not transdominant mutants.
    Carcinogenesis, 2001, Volume: 22, Issue:3

    Topics: Alleles; Arginine; Genes, Dominant; Humans; Mutation; Neoplasms; Polymorphism, Genetic; Tumor Suppressor Protein p53

2001
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
    Oncogene, 2001, Jan-04, Volume: 20, Issue:1

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan

2001
Influence of therapeutic doses of vincristine on the arginine-induced insulin and growth hormone secretions in man.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1979, Volume: 11, Issue:12

    Topics: Arginine; Blood Glucose; Female; Growth Hormone; Humans; Insulin; Male; Middle Aged; Neoplasms; Vincristine

1979
A cancer-associated, fast, homoarginine-sensitive electrophoretic form of serum alkaline phosphatase.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Adult; Alkaline Phosphatase; Arginine; Electrophoresis, Cellulose Acetate; Female; Homoarginine; Humans; Isoenzymes; Male; Neoplasms; Remission, Spontaneous

1978
Differential effects of cranial radiation on growth hormone response to arginine and insulin infusion.
    The Journal of pediatrics, 1978, Volume: 92, Issue:5

    Topics: Adolescent; Antineoplastic Agents; Arginine; Brain; Child; Child, Preschool; Female; Growth Hormone; Humans; Hypoglycemia; Infant; Infusions, Parenteral; Insulin; Male; Neoplasms

1978
Urinary excretion of methylarginine in human disease.
    Metabolism: clinical and experimental, 1977, Volume: 26, Issue:5

    Topics: Arginine; Female; Hepatitis; Humans; Liver Diseases; Lupus Erythematosus, Systemic; Male; Multiple Sclerosis; Neoplasms

1977
[Disorders of hemostasis in malignant neoplasms].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1977, Sep-01, Volume: 30, Issue:17

    Topics: Arginine; Blood Coagulation Disorders; Fibrin; Humans; Neoplasm Metastasis; Neoplasms; Thrombosis

1977
Tumor cytostasis mediated by LPS- or PSK-activated human plastic-adherent peripheral blood mononuclear cells.
    Cellular immunology, 1992, Oct-15, Volume: 144, Issue:2

    Topics: Animals; Arginine; Cell Communication; Cell Cycle; Cells, Cultured; Cytotoxicity, Immunologic; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Neoplasms; Proteoglycans; Putrescine; Tumor Necrosis Factor-alpha

1992
Significance of fibrin formation and dissolution in the pathogenesis and treatment of cancer.
    Medical hypotheses, 1991, Volume: 36, Issue:4

    Topics: Arginine; Fibrin; Fibrinolysis; Humans; Models, Biological; Neoplasms; Pyruvaldehyde; Sulfhydryl Compounds; Transglutaminases

1991
[Anticancer therapy with amino acid imbalance].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine

1991
Cellular models of macrophage tumoricidal effector mechanisms in vitro. Characterization of cytolytic responses to tumor necrosis factor and nitric oxide pathways in vitro.
    Journal of immunology (Baltimore, Md. : 1950), 1991, Oct-15, Volume: 147, Issue:8

    Topics: Animals; Arginine; Cytotoxicity, Immunologic; Macrophages; Male; Mice; Models, Biological; Mycobacterium bovis; Neoplasms; Nitric Oxide; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1991
Recovery of low thymic hormone levels in cancer patients by lysine-arginine combination.
    International journal of immunopharmacology, 1990, Volume: 12, Issue:4

    Topics: Adult; Aged; Arginine; Drug Combinations; Female; Humans; Lysine; Male; Middle Aged; Neoplasms; T-Lymphocytes; Thymic Factor, Circulating; Thymus Hormones

1990
Mechanisms of macrophage-mediated tumor cell killing: a comparative analysis of the roles of reactive nitrogen intermediates and tumor necrosis factor.
    International journal of cancer, 1990, Oct-15, Volume: 46, Issue:4

    Topics: Animals; Arginine; Argininosuccinic Acid; Cell Line; Cell Survival; Humans; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages; Male; Mice; Neoplasms; Nitroarginine; omega-N-Methylarginine; Propionibacterium acnes; Rats; Tumor Necrosis Factor-alpha

1990
Insulin-like growth factors in patients with nonislet cell tumors and hypoglycemia.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:4

    Topics: Arginine; Carrier Proteins; Humans; Hypoglycemia; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Neoplasms; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins

1986
A comparison of the predictive value and diagnostic efficiency of FHAP and CEA as cancer markers.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1986, Volume: 7, Issue:5-6

    Topics: Alkaline Phosphatase; Arginine; Carcinoembryonic Antigen; False Positive Reactions; Homoarginine; Humans; Neoplasms

1986
L-arginine independent macrophage tumor cytotoxicity.
    Biochemical and biophysical research communications, 1989, Dec-29, Volume: 165, Issue:3

    Topics: Animals; Arginine; Chromium Radioisotopes; Cytotoxicity, Immunologic; Glucose; Iron Radioisotopes; Leukemia L1210; Macrophage Activation; Macrophages; Mycobacterium bovis; Neoplasms; omega-N-Methylarginine; Tumor Cells, Cultured

1989
H1(0) histones of normal and cancer human cells. Amino acid composition of H1 purified by polyacrylamide gel electrophoresis.
    Molecular and cellular biochemistry, 1986, Volume: 71, Issue:2

    Topics: Amino Acids; Arginine; Carcinoma, Hepatocellular; Cell Line; Histones; Humans; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Lysine; Neoplasms

1986
A hypothesis for the mechanism of tumor killing by NG-hydroxymethyl-L-arginines.
    Medical hypotheses, 1986, Volume: 19, Issue:1

    Topics: Animals; Arginine; Cell Division; Formaldehyde; Humans; Neoplasms; Structure-Activity Relationship

1986
Induction of C-type particles in mammalian cancer cells.
    Advances in experimental medicine and biology, 1974, Volume: 44, Issue:1

    Topics: Animals; Arginine; Avian Sarcoma Viruses; Birds; Bromodeoxyuridine; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Genotype; Humans; Leukemia; Leukocytes; Neoplasms; Neoplasms, Experimental; Retroviridae; RNA-Directed DNA Polymerase; RNA, Viral; Sarcoma, Avian; Virus Cultivation; Virus Replication

1974
Arginine-rich low molecular peptides in human neoplastic serum.
    Experientia, 1974, Aug-15, Volume: 30, Issue:8

    Topics: Arginine; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Molecular Weight; Neoplasms; Peptides; Rectal Neoplasms

1974
The arginine content in fibrin clots and fibrinolysis in neoplastic diseases.
    Neoplasma, 1973, Volume: 20, Issue:2

    Topics: Arginine; Fibrin; Fibrinogen; Fibrinolysis; Humans; Neoplasm Proteins; Neoplasms; Protein Binding

1973
[Effects of oral administration of arginine on the tumor bearing mice (author's transl)].
    Jikken dobutsu. Experimental animals, 1973, Volume: 22, Issue:3

    Topics: Administration, Oral; Animals; Arginine; Body Weight; Catalase; Leukocyte Count; Liver; Male; Mice; Neoplasms; Organ Size; Sarcoma 180; Time Factors

1973
[Radioimmunoassay of arginine vasopressin].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:6

    Topics: Arginine; Humans; Methods; Neoplasms; Pituitary Gland, Posterior; Radioimmunoassay; Vasopressins

1971
Arginine content in serum protein and in serum protein fractions in cases of neoplastic disease.
    Neoplasma, 1971, Volume: 18, Issue:2

    Topics: Arginine; Blood Protein Electrophoresis; Brain Neoplasms; DNA; Esophageal Neoplasms; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Middle Aged; Neoplasms; Serum Albumin; Serum Globulins; Uterine Neoplasms

1971
The specificity of an increase of albumin fraction arginine in neoplastic diseases.
    Bulletin de l'Academie polonaise des sciences. Serie des sciences biologiques, 1971, Volume: 19, Issue:7

    Topics: Arginine; Humans; Neoplasms; Serum Albumin

1971
Patterns of amino-acid inhibition of alkaline phosphatases as an aid in cancer diagnosis.
    Oncology, 1971, Volume: 25, Issue:3

    Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acids; Animals; Arginine; Colonic Neoplasms; Female; Humans; In Vitro Techniques; Isoenzymes; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms; Phenylalanine; Rats; Valine

1971
TAMe esterase activity in human plasma under normal and pathological conditions.
    The Tohoku journal of experimental medicine, 1968, Volume: 95, Issue:2

    Topics: Arginine; Cardiovascular Diseases; Colorimetry; Diabetes Mellitus; Disease; Esterases; Glomerulonephritis; Hematologic Diseases; Humans; Hyperthyroidism; Leukemia; Neoplasms; Nephrotic Syndrome; Pancreatic Diseases; Skin Diseases; Stomach Neoplasms

1968
Chromosome aberrations in cultured cells deprived of single essential amino acids.
    Experimental cell research, 1969, Volume: 55, Issue:3

    Topics: Amino Acids; Animals; Arginase; Arginine; Autoradiography; Cell Nucleus; Chromosome Aberrations; Clone Cells; Cricetinae; Culture Media; Culture Techniques; DNA; DNA Replication; Methods; Mitosis; Neoplasms; Proteins; Thymidine; Tritium

1969
[On the differences of in vitro incorporation of C14-arginine and C14-leucine in the mitochondrial protein of various tumor and normal tissues].
    Das Deutsche Gesundheitswesen, 1965, Sep-02, Volume: 20, Issue:35

    Topics: Animals; Arginine; Carbon Isotopes; Cattle; In Vitro Techniques; Leucine; Mice; Mitochondria; Neoplasm Proteins; Neoplasms; Poultry; Rats

1965
Preparation and in vitro-in vivo evaluation of teniposide nanosuspensions.
    International journal of pharmaceutics, 2015, Jan-15, Volume: 478, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Compounding; Drug Delivery Systems; Drug Stability; Humans; Microscopy, Electron, Scanning; Nanoparticles; Neoplasms; Particle Size; Povidone; Rats, Wistar; Suspensions; Teniposide; Tumor Burden

2015
Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Dec-01, Volume: 11, Issue:23

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Butyrates; Chromatin; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Antisense; Drug Interactions; Drug Synergism; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Profiling; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mitoxantrone; Neoplasms; Oligonucleotide Array Sequence Analysis; RNA, Small Interfering; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Valproic Acid

2005
Drug activity and therapeutic synergism in cancer treatment.
    Cancer research, 1982, Volume: 42, Issue:8

    Topics: Animals; Antineoplastic Agents; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Melanoma; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Rats; Razoxane; Teniposide

1982
New anticancer drug class.
    JAMA, 1983, Mar-25, Volume: 249, Issue:12

    Topics: Child; Etoposide; Humans; Legislation, Drug; Neoplasms; Podophyllotoxin; Teniposide; United States

1983
Toxicity of anticancer drugs used in children.
    Cancer nursing, 1980, Volume: 3, Issue:5

    Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cisplatin; Daunorubicin; Doxorubicin; Humans; Methotrexate; Neoplasms; Teniposide

1980
Etoposide (VP16-213) and teniposide (VM26) comparative in vitro activities in human tumors.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Antineoplastic Agents; Cells, Cultured; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Teniposide

1982
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide

1982
Phase II study of VM-26 in adult malignancies.
    Cancer treatment reports, 1980, Volume: 64, Issue:1

    Topics: Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide; Thrombocytopenia

1980
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
    Blood, 1995, Jun-01, Volume: 85, Issue:11

    Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 11; Combined Modality Therapy; Dactinomycin; DNA-Binding Proteins; Etoposide; Female; Genes; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Whole-Body Irradiation

1995
Enhanced expression of the DNA topoisomerase II gene in response to heat shock stress in human epidermoid cancer KB cells.
    Cancer research, 1993, Mar-01, Volume: 53, Issue:5

    Topics: Camptothecin; DNA Topoisomerases, Type II; Etoposide; Gene Expression; Hot Temperature; Humans; Irinotecan; KB Cells; Neoplasms; RNA, Messenger; Teniposide

1993
Overexpression of multidrug resistance protein gene in human cancer cell lines selected for drug resistance to epipodophyllotoxins.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Drug Resistance, Multiple; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Multidrug Resistance-Associated Proteins; Neoplasms; Teniposide; Tumor Cells, Cultured

1996
Overview of early and investigational chemotherapeutic agents in solid tumors.
    Medical and pediatric oncology, 1976, Volume: 2, Issue:4

    Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Aziridines; Azo Compounds; Camptothecin; Cycloleucine; Etoposide; Floxuridine; Humans; Neoplasms; Nitrogen Mustard Compounds; Picolinic Acids; Platinum; Porfiromycin; Streptonigrin; Teniposide; Thiotepa; Tubercidin

1976
Childhood cancer: the improving prognosis.
    Postgraduate medicine, 1976, Volume: 59, Issue:2

    Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Osteosarcoma; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Rhabdomyosarcoma; Teniposide; Thioguanine; Vincristine; Wilms Tumor

1976
Comparison of the human pharmacokinetics of VM-26 and VP-16, two antineoplastic epipodophyllotixin glucopyranoside derivatives.
    European journal of cancer, 1975, Volume: 11, Issue:10

    Topics: Body Water; Etoposide; Humans; Metabolic Clearance Rate; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide

1975
Combination chemotherapy based on a model of cell recruitment by partial synchronization.
    Medical and pediatric oncology, 1975, Volume: 1, Issue:2

    Topics: Drug Therapy, Combination; Humans; Mitosis; Mitotic Index; Models, Biological; Neoplasm Metastasis; Neoplasms; Podophyllotoxin; Remission, Spontaneous; Teniposide; Time Factors; Vincristine

1975
Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells.
    Cancer research, 1992, Aug-15, Volume: 52, Issue:16

    Topics: Animals; Cell Hypoxia; Cell Survival; DNA Probes; DNA, Neoplasm; Endonucleases; Enzyme Induction; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Liver Neoplasms, Experimental; Molecular Weight; Neoplasms; Plasmids; Rats; Teniposide; Tumor Cells, Cultured; Tumor Stem Cell Assay

1992
Current perspectives on teniposide (VM-26): an international conference. Proceedings. London, September 2, 1989.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 6

    Topics: Animals; Humans; Neoplasms; Teniposide

1992
A phase I study of daily oral teniposide for 20 days.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 6

    Topics: Administration, Oral; Aged; Bone Marrow; Clinical Trials, Phase I as Topic; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Middle Aged; Nausea; Neoplasms; Teniposide; Thrombocytopenia; Vomiting

1992
Aberrant DNA topoisomerase II activity, radioresistance and inherited susceptibility to cancer.
    British journal of cancer, 1991, Volume: 63, Issue:1

    Topics: Amsacrine; Ataxia Telangiectasia; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cytarabine; Cytoplasm; DNA Repair; DNA Topoisomerases, Type II; DNA, Circular; DNA, Superhelical; Female; Fibroblasts; Gene Expression; Genetic Predisposition to Disease; Humans; Male; Neoplasms; Oncogenes; Radiation Tolerance; Teniposide; Topoisomerase II Inhibitors

1991
Human DNA topoisomerase II: evaluation of enzyme activity in normal and neoplastic tissues.
    Biochemistry, 1990, Feb-27, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Aged; Cell Cycle; DNA Topoisomerases, Type II; DNA, Bacterial; Escherichia coli; Female; Flow Cytometry; Genes, Immunoglobulin; Hot Temperature; Humans; Male; Middle Aged; Neoplasms; Organ Specificity; Placenta; Spleen; Teniposide

1990
[Phase I trial and pharmacokinetics of VM 26 combined with cisplatin administered by the intraperitoneal route without mixing time].
    Bulletin du cancer, 1989, Volume: 76, Issue:8

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Humans; Injections, Intraperitoneal; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide

1989
Treatment strategies in relation to drug action.
    NCI monographs : a publication of the National Cancer Institute, 1987, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide

1987
High-dose teniposide for refractory malignancies: a phase I study.
    Cancer treatment reports, 1986, Volume: 70, Issue:5

    Topics: Adult; Aged; Alopecia; Drug Evaluation; Female; Hematologic Diseases; Humans; Male; Middle Aged; Nausea; Neoplasms; Podophyllotoxin; Skin Diseases; Teniposide

1986