arginine has been researched along with Neoplasms in 383 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (18.28) | 18.7374 |
| 1990's | 46 (12.01) | 18.2507 |
| 2000's | 60 (15.67) | 29.6817 |
| 2010's | 119 (31.07) | 24.3611 |
| 2020's | 88 (22.98) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Chien, HC; Colas, C; Giacomini, KM; Hall, C; Schlessinger, A; Thomas, AA; Wells, A; Wolfe, H | 1 |
| Chen, Z; DiGiovanni, J; Wilder, CS | 1 |
| Richard, S; Xu, J | 1 |
| Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
| Jiang, L; Qiu, L; Wang, K | 1 |
| Du, H; Liu, SS; Qian, LX; Wang, F; Wang, XW; Xu, HX | 1 |
| Andresen, TL; Bak, M; Christensen, E; Kempen, PJ; Kristensen, K; Larsen, JB; Münter, R; Parhamifar, L | 1 |
| Ji, C; Li, Z; Liu, P; Niu, F; Qian, L; Ren, Y; Xiong, Y; Ye, Q; Yu, Y | 1 |
| Bagheri, M; Behzadi, M; Eghtedardoost, M | 1 |
| Akhmetshina, A; Burgering, B; Eisenberg, T; Fasching, S; Hörl, G; Jany-Luig, E; Kerbl-Knapp, J; Korbelius, M; Kratky, D; Kuentzel, KB; Macher, T; Mack, M; Madl, T; Meinitzer, A; Paar, M; Pertschy, B; Pirchheim, A; Rinner, B; Rodriguez Colman, MJ; Stelzl, U; Steyrer, E; Vujić, N; Zhang, F | 1 |
| Dai, W; Gong, J; Gong, Y; He, F; Li, S; Liu, Q; Tang, F; Wang, Z; Xie, C; Yang, Z; Zhang, J | 1 |
| Burke, JP; Duggan, WP; O'Connell, E; Prehn, JHM | 1 |
| Belykh, DV; Berezin, DB; Karimov, DR; Kukushkina, NV; Kustov, AV; Kustova, TV; Mal'shakova, MV; Morshnev, PK; Shukhto, OV; Smirnova, NL; Zorin, VP; Zorina, TE | 1 |
| Coyne, MJ; Drake, C; Kincaid, D; McCrann, DJ | 1 |
| Brekker, MA; Causey, CP; Knuckley, B; Rehman, FK; Sartawi, T; Sawatzky, TM | 1 |
| Han, Y; Ju, HQ; Li, B; Li, H; Li, JJ; Liao, K; Lin, JF; Lu, YX; Luo, XJ; Meng, Q; Tan, YT; Wang, ZX; Wei, C; Xu, RH; Yu, K; Zeng, ZL | 1 |
| Chen, M; Chen, X; Guo, Z; Liang, R; Tian, H; Wang, Z | 1 |
| Cavaretta, JP; Huang, L; Huang, T; Lee, MM; Moon, D; Rozen, EJ; Sallis, B; Shohet, JM; Sun, X; Verdejo-Torres, O; Wang, G; Wigglesworth, K; Wu, Q; Zhang, L; Zhang, XO | 1 |
| Choudhary, B; Mahadeva, R; Manjunath, M; Pradhan, SS; Rao K, R; Sivaramakrishnan, V; Swaroop, S | 1 |
| Chen, W; Deng, X; Hu, H; Li, J; Liu, W; Song, Q; Xing, X; Yang, W; Zhang, Y | 1 |
| Ecker, AK; Guiley, KZ; Morstein, J; Shokat, KM; Zhang, Z | 1 |
| Calder, PC; Douglas, C; McCullough, FS; Miller, LJ; Stanworth, SJ | 1 |
| Chen, L; Chen, Y; Lin, J; Liu, X; Lu, R; Wang, M; Yin, L; Zhang, J; Zhao, Z; Zheng, Y | 1 |
| deGraffenried, L; Gries, P; Harlow, B; Jolly, C; McClellan, B; Tiziani, S | 1 |
| Deng, M; Wan, L; Zhang, H | 1 |
| Bayarsaikhan, B; Börzsei, R; Hetényi, C; Lontay, B; Zsidó, BZ | 1 |
| Chen, X; Huang, J; Huang, L; Huang, S; Lin, Q; Tang, Y; Wang, S; Xu, Y; Zhu, Q; Zou, Y | 1 |
| Chen, L; Fu, S; Lin, C; Ouyang, L; Zhang, D; Zhang, J; Zheng, Q | 1 |
| Hlozkova, K; Safrhansova, L; Starkova, J | 1 |
| Brzozowska, E; Deshmukh, S | 1 |
| Andersen, MH; Ehrnrooth, E; Holmstroem, RB; Kjeldsen, JW; Lorentzen, CL; Martinenaite, E; Mørk, SK; Pedersen, AW; Svane, IM | 1 |
| Hsu, SH; Hung, WC | 1 |
| Ball, LE; Delaney, JR; Gan, W; Lin, B; Liu, L; Long, DT; Yin, S | 1 |
| Ding, Q; Dong, H; Gu, J; Li, Y; Liu, Y; Ma, X; Miao, Z; Yang, Y; Yin, W; Zang, J; Zhang, T; Zhao, Y; Zheng, X | 1 |
| Balasundaram, A; Doss, CGP | 1 |
| Deng, Z; Dong, J; Duan, J; Garrido, C; Hui, Z; Xie, T; Ye, XY | 1 |
| Chai, X; Cifelli, S; Fischer, C; Gathiaka, S; Kreamer, A; Kuvelkar, R; Liaw, A; McLaren, DG; Palte, RL; Richard Miller, J; So, SS; Wen, X | 1 |
| Chao, S; Li, B; Pei, Y; Pei, Z; Shen, Z | 1 |
| Yalta, K; Yalta, T; Yetkin, E | 1 |
| Field, GC; Pavlyk, I; Szlosarek, PW | 1 |
| Chen, J; Chen, Q; Li, X; Liang, X; Sun, S; Tang, Q; Wang, Y; Wu, R; Xu, M; Yue, X; Zhang, J | 1 |
| Fu, L; Liu, H; Niu, C; Wu, K | 1 |
| Bouley, RA; Petreaca, RC; Rasheed, S; Yoder, RJ | 1 |
| Narayanan, R; Thakker, DP | 1 |
| Bartee, E; Bartee, MY; Curtsinger, HD; Dryja, P | 1 |
| Assi, G; Faour, WH | 1 |
| Li, B; Wang, Y; Wu, X; Wu, Y; Zheng, J | 1 |
| Guo, C; Han, C; Hou, X; Wang, Z; Wu, L; Zhao, L; Zheng, X | 1 |
| Chu, YD; Lai, MW; Yeh, CT | 1 |
| Jin, H; Liu, S; Liu, Y; Wan, L; Zhang, H; Zhang, M | 1 |
| Han, X; Xu, Y; Yao, Q; You, S | 1 |
| Prasad, SK; Sindhu, R; Supreeth, M; Thanmaya, M | 1 |
| Chang, C; Chen, CP; Dong, W; Jiang, T; Xu, L; Zhang, G | 1 |
| Du, X; Duan, J; Gao, S; Ge, K; Ma, L; Wang, L; Zhang, J; Zhou, G | 1 |
| Gautier, C; Huynh, MA; Peron, C; Pol, J | 1 |
| Fang, Z; Song, C; Zhang, J | 1 |
| Avelar, RA; Brautigan, DL; Bryson, B; DiFeo, A; Gingras, AC; Haider, S; Jackson, M; Leonard, D; Narla, G; O'Connor, CM; Sangodkar, J; Schlatzer, D; Taylor, SE; Tokala, E; Upadhyay, A; Wang, Z; Westermarck, J; Wiredja, D; Xu, W | 1 |
| Adam, S; Bashtrykov, P; Baude, A; Dukatz, M; Emperle, M; Jeltsch, A; Kunert, S; Plass, C; Rathert, P | 1 |
| Chen, X; Li, Y; Li, Z; Qi, Y; Sun, X; Wang, Y; Yang, P; Zhang, N; Zhang, S; Zhong, J | 1 |
| Chen, M; Chen, X; Guo, Z; Hao, K; Lin, L; Liu, F; Sun, P; Tang, Z; Tian, H; Wang, D; Yu, H | 1 |
| Bobak, YP; Fletcher, MT; Kunz-Schughart, LA; Shuvayeva, GY; Stasyk, OV; Vovk, OI | 1 |
| Al-Hamashi, AA; Diaz, K; Huang, R | 1 |
| Buijsman, RC; de Man, J; Friesen, J; Grobben, Y; Uitdehaag, JCM; van den Hurk, H; van Groningen, J; Willemsen-Seegers, N; Zaman, GJR | 1 |
| Harada, M; Iida, Y; Kotani, H; Notsu, Y; Satoh, Y; Taniura, T | 1 |
| Golab, J; Grzywa, TM; Jasinski, M; Matryba, P; Nowis, D; Rydzynska, Z; Sosnowska, A | 1 |
| Bian, X; Feng, Q; Liu, X; Ma, X; Quan, C; Wang, Y; Yao, Y; Zheng, Z; Zhou, H | 1 |
| Anderson, JN; Bao, Y; Bartlett, JR; Bissonnette, S; Briant, AR; Carcel, C; Chan, K; Chen, H; Chen, L; Cheng, C; Chrétien, M; Conway Fitzgerald, A; Cyr, Y; Du, Y; El-Sayed, YY; Endo, T; Faraj, M; Fujimoto, K; Girsen, A; Goto, H; Hashimoto, D; Hayasaka, K; Hayase, E; Herrmann, N; Hidaka, D; Holst, JJ; Igbinosa, I; Iijima, H; Jeandidier, N; Jeong, DY; Jeong, GT; Joubert, M; Kagawa, I; Kahata, K; Kaushik, LK; Kim, SK; Kim, SR; Kuang, Y; Laird, M; Lamantia, V; Li, P; Li, Y; Li, Z; Lindsay, SE; Liu, X; Loizon, E; Lu, Z; Lyell, DJ; Ma, J; Magnani, CJ; Mahalingam, AK; Mandal, N; Mayer, G; Michimata, R; Ngo Sock, ET; Okada, K; Onozawa, M; Opigez, V; Palanisamy, M; Parienti, JJ; Park, YR; Pavlikova, B; Peyro Saint Paul, L; Ramsahye, N; Reyes, GA; Reznik, Y; Richardson, MT; Samo, IA; Sarkar, R; Shendge, AK; Shimizu, C; Shiratori, S; Steinberg, JR; Sugita, J; Sukwong, P; Sun, X; Sunagoya, K; Sunwoo, IY; Svendsen, B; Tang, L; Tang, Z; Teshima, T; Totée, C; Turner, BE; Unno, M; Vidal, H; Wang, C; Wang, M; Wang, S; Wang, X; Wang, Z; Wassef, H; Weeks, BT; Wong Chi Man, M; Xu, C; Xu, W; Yamamoto, S; Yu, H; Zhang, WY; Zhang, X; Zhong, Y | 1 |
| Annan, RS; Creasy, CL; Liu, Y; McHugh, CF; Mohammad, HP; Montes de Oca, R; Noto, PB; Piccoli, SP; Sikorski, TW; Szapacs, ME; Wagner, CD; Zappacosta, F | 1 |
| Goel, PN; Greene, MI; Grover, P | 1 |
| Kong, D; Leng, X; Liu, J; Sun, Z; Wang, W; Wang, X; Wang, Z | 1 |
| Chung, SF; Guan, X; Leung, YC; Tam, SY; Zhang, Y | 1 |
| Berent, TE; Dorschner, JM; Jatoi, A; Kumar, R; Kunz, HE; Lanza, IR; Meyer, T; Wang, X | 1 |
| Chen, R; Gan, Y; Wang, Y; Ying, S | 1 |
| Chang, M; Ding, B; Han, G; Hou, Z; Kheraif, AAA; Liang, S; Lin, J; Liu, S; Wang, M; Zhao, Y | 1 |
| Antman, EM; Castrillon, JA; Cheng, F; Eng, C; Fang, J; Hao, T; Hill, DE; Hou, Y; Huang, J; Keri, RA; Lathia, JD; Lightstone, FC; Liu, Z; Loscalzo, J; Lu, W; Ma, J; Martin, WR; Rabadan, R; Vidal, M; Wang, R; Wang, Y; Yue, H; Zhao, J; Zhou, Y | 1 |
| Abd Elmaaboud, MA; Arab, HH; Kabel, AM | 1 |
| Azurmendi, PA; Bettegowda, C; DiNapoli, SR; Douglass, J; Gabelli, SB; Hsiue, EH; Hwang, MS; Kinzler, KW; Konig, MF; Li, Y; Liu, Q; Miller, MS; Mog, BJ; Murphy, MB; Papadopoulos, N; Pardoll, DM; Paul, S; Pearlman, AH; Schaefer, A; Skora, AD; Vogelstein, B; Wang, Q; Watson, E; Wright, KM; Zhou, S | 1 |
| Mondal, S; Thompson, PR | 1 |
| Cheng, Y; Pan, Y; Rauf, A; Song, P; Wang, Y; Wu, X; Xu, K; Yan, J; Zhang, H; Zheng, R | 1 |
| Ballabio, E; Barnkob, MB; Cerundolo, V; Chen, JL; Crump, NT; Gileadi, U; Godfrey, L; Hadjinicolaou, AV; Kessler, BM; Koohy, H; Lau, IJ; McCullagh, JSO; Milne, TA; Napolitani, G; Olsen, LR; Quek, L; Salio, M; Setshedi, M; Taylor, S; Vyas, P; Walsby-Tickle, J; Xia, M; Yu, Z | 1 |
| Bae, GU; Cho, Y; Hwang, JW; Kim, SN; Kim, YK | 1 |
| Martí I Líndez, AA; Reith, W | 1 |
| Di Tullio, F; Guccione, E; Mzoughi, S; Schwarz, M | 1 |
| Amarasekera, N; Manoharan, S; Sarker, P | 1 |
| Guo, JY; Lattime, EC; White, E | 1 |
| Bratlie, KM; Rehman, TU | 1 |
| Du, J; Hong, K; Sun, Q; Zhang, X; Zhu, Y | 1 |
| Alhumaydhi, FA; Alsagaby, SA; Batiha, GE; El-Ballat, EM; El-Demerdash, FM; El-Esawi, MA; Fareed, MM; Rauf, A | 1 |
| Bansal, S; Kumari, N | 1 |
| Berglund, UW; Brautigam, L; Helleday, T; Kadamov, Y; Tsuber, V | 1 |
| Lenihan, DJ | 1 |
| Chan, GC; Fung, MKL | 1 |
| Bogeski, I; Bonhenry, D; Butorac, C; Cappello, S; Ettrich, RH; Frischauf, I; Groschner, K; Hochreiter, A; Litviňuková, M; Lunz, V; Muik, M; Pammer, T; Reha, D; Romanin, C; Schindl, R; Schober, R; Stallinger, A; Svobodová, B; Tociu, L; Zayats, V | 1 |
| Bennett, MK; Chen, J; Emberley, E; Gross, MI; Huang, T; Janes, JR; Li, W; MacKinnon, AL; Makkouk, A; Marguier, G; Murray, PJ; Neou, S; Pan, A; Parlati, F; Rodriguez, MLM; Steggerda, SM; Van de Velde, LA; Wang, T; Works, M; Zhang, J; Zhang, W | 1 |
| Abedi-Valugerdi, M; Hassan, M; Madjidzadeh, K; Shariatpanahi, SP | 1 |
| Gu, J; Gu, Y; Liang, S; Wang, Q; Wu, L; Xu, H; Yin, L; Zhang, H; Zhao, C | 1 |
| Jahani, M; Mansouri, K; Noroznezhad, F | 1 |
| Cau, L; Méchin, MC; Simon, M | 1 |
| Carvalho, SM; Cunha, ADS; Leite, MF; Lobato, ZIP; Mansur, AAP; Mansur, HS | 1 |
| Erez, A; Keshet, R | 1 |
| Dhankhar, R; Gulati, P; Kapoor, RK; Kumar, S | 1 |
| Cao, X; Gao, YN; Ke, AQ; Li, ZF; Liu, AD; Liu, JY; Luo, DN; Xu, H; Yu, YQ | 1 |
| Etrych, T; Fang, J; Imamura, T; Islam, W; Maeda, H; Subr, V; Ulbrich, K | 1 |
| Hardy, JA; MacPherson, DJ; Mills, CL; Ondrechen, MJ | 1 |
| Bosenberg, MW; Guo, JY; Hu, ZS; Jiang, C; Lattime, E; Lu, W; Maganti, A; Mehnert, JM; Poillet-Perez, L; Rabinowitz, JD; Sharp, DW; Su, X; White, E; Xie, X; Yang, Y; Zhan, L; Zheng, H | 1 |
| Classen, CF; Fiedler, T; Junghanss, C; Kreikemeyer, B; Maletzki, C; Riess, C; Shokraie, F | 1 |
| Berenjian, A; Ghasemi, Y; Morowvat, MH; Negahdaripour, M; Nezafat, N; Rahbar, MR; Zarei, M | 1 |
| Danielak, A; Kruszewski, WJ; Szefel, J | 1 |
| Harjes, U | 1 |
| Cao, B; Hu, X; Ji, Z; Luo, W; Wang, W; Wang, Z; Xing, D; Zhai, S; Zhang, D; Zhang, Y | 1 |
| Beal, FLR; Beal, JR; Beal, PR; Carvalho-Neves, N; Franco, OL; Silva, ON | 1 |
| Bulock, CR; Chabes, A; Kane, DP; Moore, EA; Sharma, S; Shcherbakova, PV; Xing, X | 1 |
| Perera, RM; Venida, A | 1 |
| Bian, Y; Hu, Y; Ishimwe, N; Jin, P; Lin, J; Liu, L; Liu, Y; Qian, J; Ren, L; Sha, R; Wen, LP; Yin, S; Zhang, W; Zhang, Y | 1 |
| Bogaerts, A; Ghasemitarei, M; Razzokov, J; Shokri, B; Yusupov, M | 1 |
| Chen, X; Guo, T; Hu, Y; Li, Y; Li, Z; Liu, Y; Qiu, Y; Song, J; Wang, H; Yang, H | 1 |
| Chu, CC; Ji, Y; Li, J; Shan, S; Zhao, J | 1 |
| Patil, S; Sarode, GS; Sarode, SC; Sharma, NK | 1 |
| Chang, SF; Godec, A; Hawkins, WG; Hirbe, AC; Prudner, BC; Rathore, R; Robinson, AM; Van Tine, BA | 1 |
| Chakrabandhu, S; Chitapanarux, I; Chitapanarux, T; Chottaweesak, P; Jiratrachu, R; Pisprasert, V; Rasio, W; Sripan, P; Traisathit, P | 1 |
| Davies, CC; Jarrold, J | 1 |
| Hartley, AV; Jin, J; Lu, T; Martin, M | 1 |
| Epifano, F; Felaco, M; Ferrone, A; Fiorito, S; Franceschelli, S; Gatta, DMP; Genovese, S; Grilli, A; Patruno, A; Pesce, M; Quiles, JL; Speranza, L; Taddeo, VA | 1 |
| Ke, C; Liu, P; Wang, X; Xu, S; Zou, S | 1 |
| Guccione, E; Richard, S | 1 |
| Corbo, C; Orrù, S; Salvatore, F | 1 |
| Bailey, TL; O'Connor, TR; Richard, S; Thandapani, P | 1 |
| Cairns, RA; Mak, TW | 1 |
| Hao, L; Song-Tao, Q; Xiao-Feng, H; Ye, S; Yi, L; Yun-Tao, L | 1 |
| Fujii, C; Fujino, M; Fukunaga, M; Hachino, Y; Hamaguchi, Y; Imamura, H; Iseki, C; Ishizaka, T; Kamigaki, S; Kawabata, R; Kawase, T; Kimura, Y; Yamamoto, E | 1 |
| VRAT, V | 1 |
| Clegg, JM; Fay, MM; Powers, MA; Uchida, KA; Ullman, KS | 1 |
| Campos, OA; Carey, MF; Kurdistani, SK; Macadangdang, BR; Oberai, A; Sheng, F; Spektor, T; Vogelauer, M | 1 |
| Adamkiewicz-Drozynska, E; Stachowicz-Stencel, T; Synakiewicz, A | 1 |
| Eli, M; Kong, B; Mamtimin, B; Turahun, A; Upur, H | 1 |
| Alves, ID; Jobin, ML | 1 |
| Boretsky, YR; Gonchar, MV; Sibirny, AA; Stasyk, OV | 1 |
| Feun, LG; Kuo, MT; Savaraj, N | 2 |
| Gudmann, NS; Hansen, NU; Jensen, AC; Karsdal, MA; Siebuhr, AS | 1 |
| Krebs, JE; Shechter, D; Stopa, N | 1 |
| Akande, T; Bomalaski, JS; Diaz, M; Dutia, MP; Gandara, DR; Gong, IY; Kelly, K; Lara, PN; Li, T; Mahaffey, N; Pan, CX; Semrad, T; Thomson, JA; Tomlinson, BK | 1 |
| Didelija, IC; Marini, JC | 1 |
| Choi, BY; Keum, YS | 1 |
| Huang, J; Qiu, F; Sui, M | 1 |
| Martindale, RG; Moore, FA; Rosenthal, MD; Vanzant, EL | 1 |
| Queiroz, JA; Sousa, Â; Sousa, F | 1 |
| Chang, JT; Davies, MA; Feun, LG; Kuo, MT; Liu, H; Long, Y; Park, JR; Rodriguez-Canales, J; Savaraj, N; Tsai, WB; Wistuba, II | 1 |
| Bordeleau, F; Califano, JP; LaValley, DJ; Mason, BN; Negrón Abril, YL; Reinhart-King, CA; Shin, SJ; Weiss, RS | 1 |
| Georgakis, MK; Latsios, G; Oikonomou, E; Papageorgiou, N; Papaioannou, S; Siasos, G; Tousoulis, D; Zaromitidou, M | 1 |
| Cao, W; Gao, G; Gu, Y; Li, S; Liu, M; Shan, L; Wu, C; Xu, L; Zhao, L | 1 |
| Li, G; Liu, F; Yang, Y; Zhang, L; Zhou, Y | 1 |
| Deng, X; Dohmae, N; Hamamoto, R; Nakakido, M; Nakamura, Y; Piao, L; Suzuki, T; Von Keudell, G; Yoshioka, Y | 1 |
| Bachman, M; Balasubramanian, S; Chin, JW; Elsässer, SJ; Mahesh, M; Walker, OS | 1 |
| Janakiram, NB; Kumar, G; Madka, V; Mohammed, A; Rao, CV | 1 |
| Choi, M; Gujrati, V; Jon, S; Kang, S; Kim, H; Kim, JI; Lee, J; Lee, Y; Saw, PE | 1 |
| De Santo, C; Fultang, L; Mussai, F; Vardon, A | 1 |
| Chandana, T; Venkatesh, YP | 1 |
| Ashcroft, M; Burrows, N; Cane, G; Frezza, C; Gaude, E; Howat, WJ; Maxwell, PH; Pedley, RB; Robson, M; Szlosarek, PW | 1 |
| Botelho, MG; Lau, SK; Lo, RC; Teng, JL; Woo, PC; Xiong, L | 1 |
| Babykutty, S; Banerjee, UC; Bhaumik, J; Fukumura, D; Patil, MD | 1 |
| Arachchillage, DR; Baglin, T; Besser, M; Maclean, R; van Veen, JJ | 1 |
| Amin, ML; Kim, D; Kim, S | 1 |
| Chen, H; Gupta, V; Lorton, B; Shechter, D | 1 |
| Suematsu, M; Yamamoto, T | 1 |
| Corbo, L; Le Romancer, M; Poulard, C | 1 |
| Chang, JT; Chen, HH; Estecio, M; Feun, LG; Kuo, MT; Long, Y; Savaraj, N; Tsai, WB; Wangpaichitr, M | 1 |
| Albaugh, VL; Barbul, A; Pinzon-Guzman, C | 1 |
| Peng, C; Wong, CC | 1 |
| Kuroda, S; Yugi, K | 1 |
| Chen, J; He, G; Huang, Z; Yan, Q; Yi, X; Yin, Y; Zeng, T; Zhang, L; Zhang, Y | 1 |
| Fujita, T; Furuhata, M; Hattori, Y; Kawakami, H; Maitani, Y; Toma, K | 1 |
| Aletta, JM; Hu, JC | 1 |
| BACH, SJ; LASNITZKI, I | 2 |
| Klose, RJ; Ng, SS; Oppermann, U; Yue, WW | 1 |
| Bera, S; Ray, M; Ray, S; Wallimann, T | 1 |
| Bazer, FW; Carey Satterfield, M; Davis, TA; Kim, SW; Li, P; Marc Rhoads, J; Smith, SB; Spencer, TE; Wu, G; Yin, Y | 1 |
| Bellone, M; Capuano, G; Freschi, M; Grioni, M; Rigamonti, N | 1 |
| Cho, EC; Durant, ST; La Thangue, NB | 1 |
| Fujisaki, Y; Horii, Y; Nagai, K; Shen, J | 1 |
| Boelens, PG; De Bandt, JP; Dejong, CH; Deutz, NE; Ligthart-Melis, GC; van de Poll, MC; van den Tol, MP; van Leeuwen, PA; van Schaik, C; Vermeulen, MA | 1 |
| Clerkin, K; Liang, JF; Shah, K; Tu, Z; Volk, M | 1 |
| Glenfield, K; Jeyanthan, K; Mitchell, TR; Zhu, XD | 1 |
| Gunduz, M; Mita, Y; Naomoto, Y; Ouchida, M; Sakai, A; Shimizu, K; Tanabe, S; Toyooka, S; Yamamoto, H; Yasuda, Y | 1 |
| Hauser, AT; Heinke, R; Jung, M; Sippl, W; Spannhoff, A | 1 |
| Munder, M | 1 |
| Kim, PH; Kim, SW; Kim, TI; Yockman, JW; Yun, CO | 1 |
| Cavaillès, V; Corbo, L; Jalaguier, S; Le Romancer, M; Sentis, S; Teyssier, C | 1 |
| Choi, YB; Kim, NY; Kim, SW; Park, SH; Shin, S; Yang, JM | 1 |
| Crook, T; Delage, B; Fennell, DA; Lemoine, NR; McNeish, I; Nicholson, L; Szlosarek, PW | 1 |
| Guo, K; Hu, H; Li, J; Ma, Q; Sha, H; Wang, Z; Zhang, D; Zhang, M | 1 |
| IRONS, WG | 1 |
| Field, HI; Hamamoto, R; Hayami, S; Kelly, JD; Maehara, Y; Nakamura, Y; Neal, DE; Ponder, BA; Toyokawa, G; Tsunoda, T; Unoki, M; Yoshimatsu, M | 1 |
| Reitman, ZJ; Yan, H | 1 |
| Chen, BG; Liu, Z; Lu, Y; Mao, HM; Wei, W; Xiong, WJ | 1 |
| Chen, RL; Huang, Y; Lee, HJ; Li, JF | 1 |
| Bobak, YP; Kurlishchuk, YV; Sibirny, AA; Stasyk, OV; Vynnytska, BO | 1 |
| Bobak, YP; Kurlishchuk, YV; Mayevska, OM; Stasyk, OV; Vynnytska, BO | 1 |
| GREENSTEIN, JP; LEUTHARDT, FM | 1 |
| Aletta, JM; Beghelli, S; Della Peruta, M; Mafficini, A; Mojica, WD; Mombello, A; Moratti, E; Scarpa, A; Sorio, C; Vezzalini, M | 1 |
| Li, L; Li, N; Liu, Y; Ni, Y; Schwaneberg, U; Sun, Z; Zhu, L | 1 |
| Adoue, V; Arnaud, J; Coudane, F; Méchin, MC; Nachat, R; Serre, G; Simon, M | 1 |
| Aldawsari, H; Blatchford, DR; Dufès, C; Edrada-Ebel, R; Raj, BS; Tate, RJ; Tetley, L | 1 |
| Lee, YH; Stallcup, MR | 1 |
| Chang, YC; Liang, YF; Shen, LJ; Wei, MF; Wu, FL; Yo, HH | 1 |
| Behrens, A; Davis, H; Lewis, A; Spencer-Dene, B; Stamp, G; Tateossian, H; Tomlinson, I | 1 |
| Morassutti, I; Paccagnella, A; Rosti, G | 1 |
| Aldawsari, H; Blatchford, DR; Dufès, C; Edrada-Ebel, R; Tate, RJ; Tetley, L | 1 |
| Dwarakanath, BS; Ganguli, M; Jiang, Y; Kalra, N; Khanduri, R; Langel, U; Mann, A; Naik, R; Shukla, V; Singh, AK; Thakur, G | 1 |
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| Campbell, E; Kilfeather, R; Stitt, A; Wheatley, DN | 1 |
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| Bannai, K; Ishigaki, S; Ishii, B; Kogawa, K; Kohgo, Y; Koshida, Y; Kumai, R; Mogi, Y; Niitsu, Y; Urushizaki, I | 1 |
| Holcenberg, JS | 1 |
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| Brittenden, J; Eremin, O; Heys, SD; Park, KG; Ross, J | 1 |
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| Bonaïti-Pellié, C; Brugières, L; Chompret, A; Flamant, F; Gardes, M; Lemerle, J; Martin, A; Meresse, V; Moutou, C; Poisson, N | 1 |
| Gardiner, KR; Kirk, SJ; Neilly, PJ; Rowlands, BJ | 1 |
| Eremin, O; Gough, DB; Heys, SD; Khan, L | 1 |
| Carlberg, M; Johansson, KU | 1 |
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| Griffith, OW; Kilbourn, RG | 2 |
| Bunnak, A; Chockvivatanavanit, S; Chuntrasakul, C; Leowattana, W; Sarasombath, S; Siltharm, S; Sittapairochana, C | 1 |
| Barber, MD; Delmore, G; Fearon, KC; Loprinzi, CL | 1 |
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| Keshava, C; McCanlies, EC; Sharp, DS; Sun, Y; Weston, A | 1 |
| Lima, LA; Novaes, MR | 1 |
| Field, CJ; Johnson, I; Pratt, VC | 1 |
| Lamb, J; Scott, L; Smith, S; Wheatley, DN | 1 |
| Furuuchi, K; Hirai, A; Iggo, RD; Kaneda, M; Matsumoto, J; Mitsumoto, Y; Moriuchi, T; Tada, M; Takahashi, M | 1 |
| Pham, HT; Ruediger, R; Walter, G | 1 |
| Doi, H; Komatsu, H; Nishihira, T; Satomi, S | 1 |
| Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H | 1 |
| Dechelotte, P; Nitenberg, G | 1 |
| Abumrad, NN; Barber, A; D'Olimpio, JT; Hourihane, A; May, PE | 1 |
| Campbell, E; Wheatley, DN | 1 |
| Caviezel, F; Girardi, AM; Murari, M; Poli, M; Pozza, G | 1 |
| Ehrmeyer, SL; Joiner, BL; Kahan, L; Larson, FC; Metzenberg, RL | 1 |
| Berry, DH; Dickinson, L; Dickinson, WP; Elders, MJ; Fiser, RH; Irvin, M; Schedewie, H | 1 |
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| Carnegie, PR; Fellows, FC; Symington, GR | 1 |
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| Kobayashi, Y; Watanabe, N; Yoshikawa, T | 1 |
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| Matsumoto, H; Mori, S | 1 |
| Hung, MC; Klostergaard, J; Leroux, ME | 1 |
| Cacciatore, L; Fabris, N; Lingetti, M; Mocchegiani, E; Talarico, M | 1 |
| Keist, R; Keller, R; Leist, TP; van der Meide, PH; Wechsler, A | 1 |
| Alexander, JW; Peck, MD | 1 |
| Blackburn, GL; Lowell, JA; Parnes, HL | 1 |
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| Bowser-Finn, RA; Kahan, L; Larson, FC; Traver, MI | 1 |
| Kiyotaki, C | 1 |
| Klostergaard, J; Leroux, ME | 1 |
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| Csiba, A; Rusznák, I; Trézl, L | 1 |
| Balabanova, G; Becker, Y; Kotler, M; Weinberg, E | 1 |
| Landon, J; Ratcliffe, JG; Rees, LH; Scott, AP | 1 |
| Farbiszewski, R; Rzeczycki, W | 1 |
| Farbiszewski, R; Glowinski, S; Rzeczycki, W; Worowski, K | 1 |
| Asano, H; Kojima, R; Shimada, K | 1 |
| Inoue, M; Nagata, Y | 1 |
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| Farbiszewski, R; Rzeczycki, W; Worowski, K | 2 |
| Kellen, JA; Lustig, V | 1 |
| Abe, K; Kumagai, N; Mouri, T; Seki, T; Yoshinaga, K | 1 |
| Freed, JJ; Schatz, SA | 1 |
| Butschak, G; Graffi, A; Schneider, EJ | 1 |
| Duan, L; He, S; Li, Y; Yang, H; Zhang, R | 1 |
| Bicaku, E; Daud, AI; Marchion, DC; Munster, PN; Sullivan, DM; Turner, JG | 1 |
| Marik, PE; Vahid, B | 1 |
| Pawlicki, M; Zuchowska-Vogelgesang, B | 1 |
| Płuzańska, A; Robak, T | 1 |
| Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ | 1 |
| Campbell, ED; Carter, WH; Stablein, DM; Wampler, GL | 1 |
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| Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA | 1 |
| Schulz, JJ; Speckhart, VJ; Spremulli, E; Wampler, GL | 1 |
| Felix, CA; Hosler, MR; Lange, BJ; Masterson, M; Wilson, AE; Winick, NJ | 1 |
| Muggia, FM | 1 |
| Joel, SP; Slevin, ML | 1 |
| Crist, WM; Pratt, CB; Pui, CH; Rivera, GK; Santana, VM | 1 |
| Evans, WE; McLeod, HL | 1 |
| Kohno, K; Kuwano, M; Matsuo, K; Sato, S; Tanimura, H; Uchiumi, T; Yamada, Y | 1 |
| Abe, T; Hisano, T; Kohno, K; Koike, K; Kubo, T; Kuwano, M; Wada, M | 1 |
| Furukawa, M; Harada, T; Kuwano, M; Tanaka, T | 1 |
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| de Jong, RS; de Vries, EG; Groen, HJ; Höppener, FJ; Mulder, NH; Sleijfer, DT; Uges, DR; van der Graaf, WT; Willemse, PH | 1 |
| Carter, SK; Slavik, M | 1 |
| Adamson, RH; Mead, JA; Sieber, SM | 1 |
| Carter, SK; Muggia, FM; Rozencweig, M; Slavik, M | 1 |
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143 review(s) available for arginine and Neoplasms
| Article | Year |
|---|---|
Pharmacologic approaches to amino acid depletion for cancer therapy.
Topics: Amino Acids; Arginine; Glutamine; Humans; Neoplasms; Oxidation-Reduction | 2022 |
Cellular pathways influenced by protein arginine methylation: Implications for cancer.
Topics: Alternative Splicing; Animals; Arginine; B7-H1 Antigen; Cell Communication; Cell Line, Tumor; CRISPR-Cas Systems; DNA Damage; DNA Repair; Enzyme Inhibitors; Epigenesis, Genetic; Histones; Humans; Immune System; Immunotherapy; Methylation; Mice; Mice, Knockout; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; RNA Splicing; RNA, Messenger; Signal Transduction | 2021 |
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
Arginase: An emerging and promising therapeutic target for cancer treatment.
Topics: Animals; Arginase; Arginine; Mammals; Neoplasms; Tumor Microenvironment; Urea | 2022 |
Protein Arginine Methylation: An Emerging Modification in Cancer Immunity and Immunotherapy.
Topics: Arginine; Humans; Immunologic Factors; Immunotherapy; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases; Quality of Life | 2022 |
Serine-Arginine Protein Kinase 1 (SRPK1): a systematic review of its multimodal role in oncogenesis.
Topics: Arginine; Arginine Kinase; Carcinogenesis; Cell Transformation, Neoplastic; Humans; Neoplasms; NF-kappa B; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; RNA Splicing Factors; Serine; Transforming Growth Factor beta | 2022 |
Impact of enteral immunonutrition on infectious complications and immune and inflammatory markers in cancer patients undergoing chemotherapy: A systematic review of randomised controlled trials.
Topics: Adult; Arginine; Biomarkers; Fatty Acids, Omega-3; Glutamine; Humans; Malnutrition; Neoplasms; Nucleotides; Randomized Controlled Trials as Topic; Tumor Necrosis Factor-alpha; Vitamin A; Vitamins | 2022 |
SR Splicing Factors Promote Cancer via Multiple Regulatory Mechanisms.
Topics: Arginine; Humans; Neoplasms; RNA; RNA Splicing Factors; RNA-Binding Proteins; Serine; Serine-Arginine Splicing Factors | 2022 |
Medicinal chemistry strategies targeting PRMT5 for cancer therapy.
Topics: Arginine; Chemistry, Pharmaceutical; Enzyme Inhibitors; Humans; Molecular Targeted Therapy; Neoplasms; Protein-Arginine N-Methyltransferases | 2022 |
Targeting amino acid metabolism in cancer.
Topics: Amino Acids; Arginine; Asparagine; Cysteine; Humans; Methionine; Neoplasms | 2022 |
Integrin Alpha v Beta 6 (αvβ6) and Its Implications in Cancer Treatment.
Topics: Antigens, Neoplasm; Arginine; Aspartic Acid; Glycine; Humans; Integrin alphaV; Integrins; Neoplasms; Oligopeptides; Transforming Growth Factor beta | 2022 |
Protein arginine methyltransferase 3: A crucial regulator in metabolic reprogramming and gene expression in cancers.
Topics: Arginine; Gene Expression; Humans; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases | 2023 |
An updated patent review of protein arginine N-methyltransferase inhibitors (2019-2022).
Topics: Arginine; Enzyme Inhibitors; Humans; Neoplasms; Patents as Topic; Protein-Arginine N-Methyltransferases | 2022 |
Bench-to-Bedside Studies of Arginine Deprivation in Cancer.
Topics: Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Humans; Hydrolases; Neoplasms; Polyethylene Glycols | 2023 |
Research progress on PRMTs involved in epigenetic modification and tumour signalling pathway regulation (Review).
Topics: Arginine; Carcinogenesis; Epigenesis, Genetic; Humans; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Signal Transduction; Tumor Microenvironment | 2023 |
Arginine deiminase produced by lactic acid bacteria as a potent anti-cancer drug.
Topics: Antineoplastic Agents; Arginine; Bacteria; Humans; Hydrolases; Lactobacillales; Neoplasms | 2023 |
Arginine deprivation as a treatment approach targeting cancer cell metabolism and survival: A review of the literature.
Topics: Amino Acids; Apoptosis; Arginine; Cell Death; Cell Line, Tumor; Humans; Neoplasms | 2023 |
Targeting Arginine Methyltransferase PRMT5 for Cancer Therapy: Updated Progress and Novel Strategies.
Topics: Arginine; Histones; Humans; Intracellular Signaling Peptides and Proteins; Neoplasms; Protein-Arginine N-Methyltransferases | 2023 |
Unlocking the Potential of Arginine Deprivation Therapy: Recent Breakthroughs and Promising Future for Cancer Treatment.
Topics: Arginine; Argininosuccinate Synthase; Cell Death; Cell Line, Tumor; Humans; Hydrolases; Neoplasms; Polyethylene Glycols | 2023 |
Research progress on the role of cationic amino acid transporter (CAT) family members in malignant tumors and immune microenvironment.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Animals; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Humans; Mammals; Neoplasms; Tumor Microenvironment | 2023 |
Shuttle between arginine and lysine: influence on cancer immunonutrition.
Topics: Amino Acids; Arginine; Diet; Immunonutrition Diet; Lysine; Neoplasms | 2023 |
Non-Histone Arginine Methylation by Protein Arginine Methyltransferases.
Topics: Antineoplastic Agents; Arginine; Cardiovascular Diseases; Enzyme Inhibitors; Epigenesis, Genetic; Histones; Humans; Metabolic Diseases; Methylation; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; RNA Splicing; Signal Transduction; Transcription Factors | 2020 |
Myeloid Cell-Derived Arginase in Cancer Immune Response.
Topics: Animals; Antineoplastic Agents; Arginase; Arginine; Clinical Trials as Topic; Humans; Macrophages; Mice; Myeloid Cells; Myeloid Progenitor Cells; Neoplasms | 2020 |
PRMT5 and Tip60 Modify FOXP3 Function in Tumor Immunity.
Topics: Arginine; Epigenesis, Genetic; Forkhead Transcription Factors; Humans; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases | 2020 |
Arginine deprivation as a strategy for cancer therapy: An insight into drug design and drug combination.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Arginase; Arginine; Clinical Trials as Topic; Drug Design; Humans; Hydrolases; Neoplasms | 2021 |
The roles of PAD2- and PAD4-mediated protein citrullination catalysis in cancers.
Topics: Animals; Arginine; Citrulline; Humans; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminase Type 4 | 2021 |
Chemical biology of protein citrullination by the protein A arginine deiminases.
Topics: Animals; Arginine; Autoimmune Diseases; Catalysis; Citrullination; Citrulline; Epigenesis, Genetic; Humans; Neoplasms; Neurodegenerative Diseases; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Proteins | 2021 |
Protein arginine methyltransferases: promising targets for cancer therapy.
Topics: Antineoplastic Agents; Arginine; Biomarkers, Tumor; Cell Cycle; Disease Management; Disease Susceptibility; DNA Damage; Drug Development; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Methylation; Molecular Targeted Therapy; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases | 2021 |
Arginine-dependent immune responses.
Topics: Animals; Arginine; Communicable Diseases; Humans; Immunity; Neoplasms | 2021 |
Cancer synthetic vulnerabilities to protein arginine methyltransferase inhibitors.
Topics: Arginine; Humans; Methylation; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases | 2021 |
Autophagy Regulates Stress Responses, Metabolism, and Anticancer Immunity.
Topics: Adaptive Immunity; Alanine; Animals; Antineoplastic Agents; Arginine; Autophagy; Drug Resistance, Neoplasm; Humans; Lymphocyte Activation; Metabolic Networks and Pathways; Mice; Models, Animal; Neoplasms; Stress, Physiological; T-Lymphocytes; Tumor Escape | 2021 |
Arginine depriving enzymes: applications as emerging therapeutics in cancer treatment.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arginine; Autophagy; Cell Proliferation; Enzymes; Humans; Neoplasms; Oxidative Stress | 2021 |
Drug-induced amino acid deprivation as strategy for cancer therapy.
Topics: Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Arginine; Asparaginase; Glutamine; Humans; Neoplasms | 2017 |
Arginine: Challenges and opportunities of this two-faced molecule in cancer therapy.
Topics: Animals; Arginine; Carcinogenesis; Humans; Immunity; Metabolome; Models, Biological; Neoplasms | 2018 |
Peptidylarginine deiminases and deiminated proteins at the epidermal barrier.
Topics: Animals; Arginine; Arthritis, Rheumatoid; Calcium; Citrulline; Epidermal Cells; Epidermis; Filaggrin Proteins; Gene Expression Profiling; Gene Expression Regulation; Humans; Hydrolases; Inflammation; Mice; Neoplasms; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminases | 2018 |
Arginine and the metabolic regulation of nitric oxide synthesis in cancer.
Topics: Animals; Antineoplastic Agents; Arginine; Humans; Models, Biological; Neoplasms; Nitric Oxide | 2018 |
Arginine-lowering enzymes against cancer: a technocommercial analysis through patent landscape.
Topics: Animals; Antineoplastic Agents; Arginine; Drug Design; Humans; Hydrolases; Neoplasms; Patents as Topic; Polyethylene Glycols | 2018 |
Arginine-Depleting Enzymes - An Increasingly Recognized Treatment Strategy for Therapy-Refractory Malignancies.
Topics: Arginase; Arginine; Humans; Hydrolases; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Proto-Oncogene Proteins c-myc; Recombinant Proteins; Tumor Microenvironment | 2018 |
Arginine Deiminase: Current Understanding and Applications.
Topics: Antineoplastic Agents; Arginine; Clinical Trials as Topic; Cloning, Molecular; Escherichia coli; Gene Expression; Humans; Hydrolases; Models, Molecular; Mycoplasma; Mycoplasma penetrans; Neoplasms; Patents as Topic; Protein Engineering; Protein Structure, Secondary; Pseudomonas aeruginosa; Recombinant Proteins | 2019 |
Metabolic pathways of L-arginine and therapeutic consequences in tumors.
Topics: Animals; Arginine; Humans; Metabolic Networks and Pathways; Myeloid-Derived Suppressor Cells; Neoplasms | 2019 |
Perspectives on the Therapeutic Benefits of Arginine Supplementation in Cancer Treatment.
Topics: Animals; Antineoplastic Agents; Arginine; Dietary Supplements; Humans; Neoplasms; Treatment Outcome | 2019 |
PRMTs and Arginine Methylation: Cancer's Best-Kept Secret?
Topics: Animals; Antineoplastic Agents; Arginine; DNA Damage; Drug Resistance; Epigenomics; Histones; Humans; Immunotherapy; Methylation; Mice; Molecular Targeted Therapy; Neoplasms; Protein Processing, Post-Translational; Protein Splicing; Protein-Arginine N-Methyltransferases; RNA Splicing; Stem Cells | 2019 |
PRMTs and miRNAs: functional cooperation in cancer and beyond.
Topics: 3' Untranslated Regions; Arginine; Cardiovascular Diseases; Epigenesis, Genetic; Histones; Humans; Inflammation; Methylation; MicroRNAs; Neoplasms; Neurodegenerative Diseases; Peptide Chain Initiation, Translational; Protein Binding; Protein-Arginine N-Methyltransferases | 2019 |
Arginine metabolism and deprivation in cancer therapy.
Topics: Animals; Antineoplastic Agents; Arginine; Clinical Trials as Topic; Drug Discovery; Drug Evaluation, Preclinical; Humans; Hydrolases; Neoplasms; Polyethylene Glycols | 2019 |
The regulation, functions and clinical relevance of arginine methylation.
Topics: Animals; Arginine; Humans; Methylation; Neoplasm Proteins; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Signal Transduction | 2019 |
SRp20: an overview of its role in human diseases.
Topics: Alternative Splicing; Amino Acid Sequence; Arginine; Gene Expression Regulation, Neoplastic; Humans; Molecular Sequence Data; Neoplasms; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; RNA Splicing; RNA-Binding Proteins; RNA, Messenger; RNA, Small Nuclear; Sequence Homology, Amino Acid; Serine; Serine-Arginine Splicing Factors | 2013 |
Defining the RGG/RG motif.
Topics: Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Apoptosis; Arginine; DNA Damage; Fragile X Syndrome; Humans; Methylation; Molecular Sequence Data; Neoplasms; Neuromuscular Diseases; Protein Biosynthesis; Protein Interaction Domains and Motifs; Proteins | 2013 |
Oncogenic isocitrate dehydrogenase mutations: mechanisms, models, and clinical opportunities.
Topics: Animals; Arginine; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Knock-In Techniques; Glutarates; Humans; Isocitrate Dehydrogenase; Mice; Mutation; Neoplasms | 2013 |
Association between the XRCC1 Arg399Gln polymorphism and risk of cancer: evidence from 297 case-control studies.
Topics: Arginine; Asian People; Case-Control Studies; DNA-Binding Proteins; Genetic Predisposition to Disease; Humans; Neoplasms; X-ray Repair Cross Complementing Protein 1 | 2013 |
The role of arginine and the modified arginine deiminase enzyme ADI-PEG 20 in cancer therapy with special emphasis on Phase I/II clinical trials.
Topics: Animals; Antineoplastic Agents; Arginine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Humans; Hydrolases; Molecular Targeted Therapy; Neoplasms; Polyethylene Glycols; Randomized Controlled Trials as Topic | 2014 |
On the importance of electrostatic interactions between cell penetrating peptides and membranes: a pathway toward tumor cell selectivity?
Topics: Amino Acid Sequence; Arginine; Cell Membrane; Cell-Penetrating Peptides; Humans; Models, Biological; Molecular Sequence Data; Neoplasms; Protein Binding; Static Electricity | 2014 |
Recombinant arginine-degrading enzymes in metabolic anticancer therapy and bioanalytics.
Topics: Antineoplastic Agents; Arginase; Arginine; Humans; Hydrolases; Neoplasms; Recombinant Proteins | 2015 |
Arginine deprivation in cancer therapy.
Topics: Antineoplastic Agents; Arginase; Arginine; Argininosuccinate Synthase; Humans; Hydrolases; Neoplasms; Polyethylene Glycols | 2015 |
Biological relevance of citrullinations: diagnostic, prognostic and therapeutic options.
Topics: Arginine; Arthritis, Rheumatoid; Autoantibodies; Benzamidines; Biomarkers; Citrulline; Enzyme Inhibitors; Fibrosis; Humans; Hydrolases; Isoenzymes; Multiple Sclerosis; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Spondylitis, Ankylosing | 2015 |
The PRMT5 arginine methyltransferase: many roles in development, cancer and beyond.
Topics: Adaptor Proteins, Signal Transducing; Arginine; Catalytic Domain; Cell Differentiation; Gene Expression Regulation; Histones; Humans; Methylation; Multiprotein Complexes; Neoplasms; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Quaternary; Protein-Arginine N-Methyltransferases | 2015 |
Isocitrate dehydrogenase mutations: new opportunities for translational research.
Topics: Arginine; Enzyme Inhibitors; Glutarates; Humans; Isocitrate Dehydrogenase; Isoenzymes; Mutation, Missense; Neoplasms; Translational Research, Biomedical | 2015 |
Targeting arginine metabolism pathway to treat arginine-dependent cancers.
Topics: Arginine; Cell Death; Humans; Neoplasms | 2015 |
Asymmetric Dimethylarginine: Clinical Significance and Novel Therapeutic Approaches.
Topics: Alzheimer Disease; Animals; Arginine; Cardiovascular Diseases; Diabetes Mellitus; Female; Humans; Hypercholesterolemia; Neoplasms; Pre-Eclampsia; Pregnancy; Renal Insufficiency, Chronic | 2015 |
Prevention and treatment of cancers by immune modulating nutrients.
Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes | 2016 |
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
Topics: Animals; Antineoplastic Agents; Arginase; Arginine; Cell Proliferation; Cell Survival; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Therapy; Humans; Hydrolases; Metabolic Networks and Pathways; Neoplasms; Signal Transduction; Stress, Physiological | 2016 |
Occurrence, Functions and Biological Significance of Arginine-Rich Proteins.
Topics: Amino Acids; Arginine; Dietary Proteins; Humans; Neoplasms; Proteins; Virus Diseases | 2016 |
Arginine Metabolism in Bacterial Pathogenesis and Cancer Therapy.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Arginase; Arginine; Bacteria; Bacterial Infections; Drug Resistance, Bacterial; Gene Expression Regulation; Humans; Hydrolases; Neoplasms; Signal Transduction | 2016 |
Arginine dependence of tumor cells: targeting a chink in cancer's armor.
Topics: Arginase; Arginine; Argininosuccinate Synthase; Gene Expression Regulation, Neoplastic; Humans; Hydrolases; Neoplasms; Ornithine Carbamoyltransferase; Signal Transduction | 2016 |
[Methionine metabolism regulates biotransformation of glucose via protein arginine methylation in cancer cells].
Topics: Animals; Arginine; Glucose; Humans; Methionine; Methylation; Neoplasms; Proteins | 2016 |
Protein arginine methylation/demethylation and cancer.
Topics: Arginine; Demethylation; Humans; Jumonji Domain-Containing Histone Demethylases; Methylation; Neoplasms; Protein Processing, Post-Translational | 2016 |
Arginine-Dual roles as an onconutrient and immunonutrient.
Topics: Animals; Arginine; Dietary Supplements; Humans; Neoplasms | 2017 |
The story of protein arginine methylation: characterization, regulation, and function.
Topics: Arginine; Cardiovascular Diseases; DNA Repair; Humans; Mass Spectrometry; Methylation; Multiple Sclerosis; Muscular Atrophy, Spinal; Neoplasms; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins; Proteomics; Signal Transduction | 2017 |
Protein arginine methylation in health and disease.
Topics: Animals; Arginine; Autoimmune Diseases; Cardiovascular Diseases; Humans; Methylation; Models, Biological; Neoplasms; Virus Diseases | 2008 |
Dynamic protein methylation in chromatin biology.
Topics: Animals; Arginine; Chromatin; DNA Damage; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Regulation; Germ Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Models, Molecular; Molecular Structure; Neoplasms; Oxidoreductases, N-Demethylating; Protein Conformation; Protein Methyltransferases; Protein Processing, Post-Translational; Tumor Suppressor Protein p53 | 2009 |
Arginine metabolism and nutrition in growth, health and disease.
Topics: Animals; Arginine; Cystic Fibrosis; Fetal Development; Humans; Metabolic Syndrome; Muscle, Skeletal; Neoplasms; Nutritional Requirements; Obesity; Reproduction; Wounds and Injuries | 2009 |
The emerging therapeutic potential of histone methyltransferase and demethylase inhibitors.
Topics: Arginine; Enzyme Inhibitors; Histone Demethylases; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Methylation; Neoplasms; Protein Processing, Post-Translational | 2009 |
Arginase: an emerging key player in the mammalian immune system.
Topics: Animals; Arginase; Arginine; Autoimmune Diseases; Humans; Immune System; Immune Tolerance; Inflammation; Mammals; Myeloid Cells; Neoplasms; Signal Transduction | 2009 |
Protein arginine methylation in estrogen signaling and estrogen-related cancers.
Topics: Animals; Arginine; Breast Neoplasms; Estrogens; Female; Humans; Male; Methylation; Models, Biological; Neoplasms; Protein-Arginine N-Methyltransferases; Receptors, Estrogen; Signal Transduction | 2010 |
Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer.
Topics: Animals; Arginine; Argininosuccinate Synthase; Humans; Neoplasms; Prognosis | 2010 |
Targeting the L-arginine-nitric oxide pathway for cancer treatment.
Topics: Animals; Arginine; Humans; Neoplasms; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase | 2010 |
Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism.
Topics: Animals; Arginine; Brain Neoplasms; Codon; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioblastoma; Glucose; Glutarates; Humans; Hypoxia; Isocitrate Dehydrogenase; Mutation; NADP; Neoplasms; Oligodendroglioma; Oncogenes; Signal Transduction; Up-Regulation | 2010 |
Targeted cellular metabolism for cancer chemotherapy with recombinant arginine-degrading enzymes.
Topics: Antineoplastic Agents; Arginase; Arginine; Argininosuccinate Synthase; Autophagy; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Hydrolases; Hypoxia-Inducible Factor 1, alpha Subunit; Molecular Targeted Therapy; Neoplasms; Polyethylene Glycols; Sp4 Transcription Factor | 2010 |
[Deimination or citrullination, a post-translational modification with many physiological and pathophysiological facets].
Topics: Animals; Arginine; Autoimmune Diseases; Body Water; Calcium; Chromatin; Citrulline; Conserved Sequence; Cornea; Epidermis; Evolution, Molecular; Gene Expression Regulation; Humans; Hydrolases; Isoenzymes; Mice; Myelin Proteins; Neoplasms; Nervous System Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 6; Protein-Arginine Deiminases; Skin Diseases | 2011 |
Nutritional intervention for improving treatment tolerance in cancer patients.
Topics: Amino Acids; Arginine; Cachexia; Dietary Supplements; Fatty Acids, Omega-3; Feeding Behavior; Glutamine; Humans; Malnutrition; Neoplasms; Nutritional Status; Nutritional Support; Weight Loss | 2011 |
The relationships of nutrients, routes of delivery, and immunocompetence.
Topics: Arginine; Dietary Supplements; Enteral Nutrition; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Glutamine; Humans; Immune System; Immune Tolerance; Immunocompetence; Malnutrition; Neoplasms; Nutritional Support; Parenteral Nutrition; Parenteral Nutrition, Total; Perioperative Care; Surgical Procedures, Operative; Wounds and Injuries | 2011 |
The role of a disturbed arginine/NO metabolism in the onset of cancer cachexia: a working hypothesis.
Topics: Arginine; Cachexia; Humans; Neoplasms; Nitric Oxide; Proteins | 2012 |
Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives.
Topics: Animals; Arginase; Arginine; Cytokines; Gene Expression Regulation, Neoplastic; Humans; Immune Tolerance; Inflammation; Mice; Myeloid Progenitor Cells; Neoplasm Proteins; Neoplasms; Signal Transduction; T-Lymphocytes | 2012 |
PGE(2)-driven induction and maintenance of cancer-associated myeloid-derived suppressor cells.
Topics: Animals; Arginase; Arginine; Chemokine CXCL12; Cyclooxygenase 2; Dinoprostone; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Myeloid Progenitor Cells; Neoplasms; Nitric Oxide Synthase Type II; Receptors, CXCR4; Signal Transduction; T-Lymphocytes | 2012 |
Protein arginine methyltransferases and cancer.
Topics: Animals; Antineoplastic Agents; Arginine; DNA Methylation; Humans; Neoplasms; Protein-Arginine N-Methyltransferases | 2013 |
[Nutrition and tumoral growth].
Topics: Animals; Arginine; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Nucleotides; Rats | 2002 |
[Modulation of immunity in cancerous patient : an weapon with double edges?].
Topics: Animals; Arginine; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Nucleotides; Treatment Outcome | 2002 |
Controlling cancer by restricting arginine availability--arginine-catabolizing enzymes as anticancer agents.
Topics: Animals; Antineoplastic Agents; Arginase; Arginine; Carboxy-Lyases; Humans; Neoplasms | 2004 |
[Arginine--metabolism and functions in the human organism].
Topics: Adult; Animals; Arginase; Arginine; Creatine; Humans; Intestine, Small; Kidney; Liver; Neoplasms; Nitric Oxide; Renal Insufficiency; Wounds and Injuries | 2004 |
Arginine transport in catabolic disease states.
Topics: Animals; Arginine; Biological Transport; Cell Membrane; Endothelium, Vascular; Humans; Infections; Inflammation; Intestinal Mucosa; Liver; Neoplasms; Wounds and Injuries | 2004 |
Arginine and cancer.
Topics: Animals; Antibody Formation; Antineoplastic Agents; Apoptosis; Arginine; Biological Transport; Disease Progression; Drug Synergism; Humans; Neoplasm Metastasis; Neoplasms; Neovascularization, Pathologic; Nitric Oxide | 2004 |
Arginine deprivation and metabolomics: important aspects of intermediary metabolism in relation to the differential sensitivity of normal and tumour cells.
Topics: Arginine; Argininosuccinate Synthase; Cell Death; Cell Division; Citrulline; Humans; Neoplasms | 2005 |
[Design and creation of cytomedicine for application to cell therapy].
Topics: Animals; Arginine; Capsules; Cell- and Tissue-Based Therapy; Dendritic Cells; Diabetes Mellitus; Drug Delivery Systems; Drug Design; Genetic Therapy; Humans; Immunotherapy; Immunotherapy, Active; Islets of Langerhans; Neoplasms; Polylysine; Regenerative Medicine | 2005 |
[L-arginine: an amino acid with multiple effects].
Topics: Arginine; Asthma; Body Constitution; Cardiovascular Diseases; Dietary Supplements; Fracture Healing; Humans; Neoplasms | 2005 |
Pegylated arginine deiminase: a novel anticancer enzyme agent.
Topics: Amino Acid Sequence; Amino Acids; Animals; Antineoplastic Agents; Arginine; Argininosuccinate Synthase; Carcinoma, Hepatocellular; Citrulline; Clinical Trials as Topic; Dexamethasone; Dogs; Drug Screening Assays, Antitumor; Drug Synergism; Drugs, Investigational; Humans; Hydrolases; Liver Neoplasms; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Molecular Sequence Data; Mycoplasma hominis; Neoplasm Proteins; Neoplasms; Nutritional Requirements; Polyethylene Glycols; Rabbits; Randomized Controlled Trials as Topic; Recombinant Proteins; Skin Neoplasms; Species Specificity; Treatment Outcome | 2006 |
[Arginine as a crucial amino acid in carcinogenesis and tumor growth].
Topics: Adult; Animals; Apoptosis; Arginine; Biological Transport; Cell Transformation, Neoplastic; Child; Disease Progression; Humans; In Vitro Techniques; Neoplasms; Neovascularization, Pathologic | 2006 |
Interplay between chromatin remodelers and protein arginine methyltransferases.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Arginine; Chromatin; Chromosomal Proteins, Non-Histone; DNA Repair; Gene Expression Regulation; Histones; Humans; Isoenzymes; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases; Transcription Factors; Transcription, Genetic | 2007 |
Myeloid-derived suppressor cells.
Topics: Animals; Antigens; Arginine; Cell Differentiation; Epitopes; Humans; Immune Tolerance; Models, Biological; Myeloid Cells; Neoplasms; Peroxynitrous Acid; Reactive Oxygen Species; T-Lymphocytes; T-Lymphocytes, Regulatory; Transforming Growth Factor beta | 2007 |
Role of arginine metabolism in immunity and immunopathology.
Topics: Animals; Arginase; Arginine; Autoimmune Diseases; Cytokines; Humans; Immunity; Immunity, Active; Immunity, Innate; Infections; Inflammation; Myeloid Cells; Neoplasms; Nitric Oxide Synthase; Wound Healing | 2007 |
Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives.
Topics: Animals; Arginase; Arginine; CD3 Complex; Enzyme Induction; Gene Expression Regulation, Neoplastic; Humans; Immune Tolerance; Immunotherapy; Mice; Models, Immunological; Myeloid Cells; Neoplasms; Signal Transduction; T-Lymphocytes; Tumor Escape | 2008 |
On the mechanism of cyclic AMP-mediated growth arrest of solid tumors.
Topics: Animals; Arginine; Bucladesine; Cell Division; Cyclic AMP; Female; Humans; Kinetics; Mammary Neoplasms, Experimental; Neoplasm Regression, Spontaneous; Neoplasms; Neoplasms, Experimental; Nucleoproteins; Phosphorylation; Rats; Receptors, Cyclic AMP | 1980 |
Current indications for intravenous nutritional support in oncology patients.
Topics: Animals; Arginine; Glutamine; Humans; Neoplasms; Nutrition Assessment; Parenteral Nutrition, Total; Preoperative Care; Randomized Controlled Trials as Topic; Treatment Outcome | 1995 |
Protein metabolism in the cancer patient.
Topics: Amino Acids, Branched-Chain; Animals; Arginine; Carbon Isotopes; Deuterium; Fasting; Humans; Neoplasms; Protein Biosynthesis | 1994 |
L-arginine and malignant disease: a potential therapeutic role?
Topics: Animals; Arginine; Humans; Neoplasms; Neoplasms, Experimental; Wound Healing | 1994 |
The Sir David Cuthbertson Medal Lecture 1992. The immunological and metabolic effects of L-arginine in human cancer.
Topics: Animals; Arginine; Cell Division; Humans; Neoplasms; Nutritional Requirements | 1993 |
The L-arginine/nitric oxide pathway--biological properties and therapeutic applications.
Topics: Animals; Arginine; Child; Disease Models, Animal; Female; Humans; Neoplasms; Nitric Oxide; Sepsis; Wounds and Injuries | 1994 |
Nutritional pharmacology and malignant disease: a therapeutic modality in patients with cancer.
Topics: Animals; Arginine; Cell Division; Fatty Acids, Essential; Glutamine; Humans; Immunity; Neoplasms; Nitrogen; Polyribonucleotides; Wound Healing | 1996 |
NO-synthase: what can research on invertebrates add to what is already known?
Topics: Animals; Arginine; Cell Death; Cytokines; Cytotoxicity, Immunologic; Endothelium, Vascular; Humans; Immunity, Cellular; Killer Cells, Natural; Macrophages; Mast Cells; Microglia; Neoplasms; Neutrophils; Nitric Oxide; Nitric Oxide Synthase | 1995 |
Clinical significance of L-arginine--nitric oxide system.
Topics: Arginine; Arteriosclerosis; Endothelium, Vascular; Humans; Neoplasms; Nitric Oxide | 1995 |
Design of nitric oxide synthase inhibitors and their use to reverse hypotension associated with cancer immunotherapy.
Topics: Animals; Arginine; Blood Pressure; Dogs; Drug Design; Enzyme Inhibitors; Humans; Hypotension; Immunotherapy; Interleukin-2; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1997 |
Erratic behavior of nitric oxide within the immune system: illustrative review of conflicting data and their immunopharmacological aspects.
Topics: Animals; Apoptosis; Arginine; Autoimmune Diseases; Cytokines; Cytotoxicity, Immunologic; Encephalomyelitis, Autoimmune, Experimental; Endotoxemia; Histocompatibility Antigens Class II; Humans; Immune System; Infections; Inflammatory Bowel Diseases; Isoenzymes; Mice; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Species Specificity | 1998 |
[Effects of dietetic supplementation with L-arginine in cancer patients. A review of the literature].
Topics: Animals; Arginine; Dietary Supplements; Humans; Neoplasms; Nutrition Disorders | 1999 |
Glutamine and arginine: immunonutrients for improved health.
Topics: Arginine; Burns; Dietary Supplements; Glutamine; Health Status; HIV Infections; Humans; Immunity, Cellular; Immunocompromised Host; Infections; Neoplasms | 2000 |
[Anti-cancer therapy with amino acid imbalance].
Topics: Amino Acids; Antimetabolites, Antineoplastic; Arginine; Asparagine; Glutamine; Humans; Isoxazoles; Methionine; Neoplasms; Valine | 2001 |
Anticoagulation: the present and future.
Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis | 2001 |
Is immune nutrition the Holy Grail for cancer patients?
Topics: Arginine; Fatty Acids, Unsaturated; Glutamine; Hospitalization; Humans; Immunotherapy; Length of Stay; Neoplasms; Nutritional Physiological Phenomena; Nutritional Support; Ornithine; Treatment Outcome | 2000 |
Arginine catabolism, liver extracts and cancer.
Topics: Animals; Arginase; Arginine; Carboxy-Lyases; Cell Cycle; Food Deprivation; Humans; Hydrolases; Liver; Liver Extracts; Neoplasms; Tumor Cells, Cultured | 2002 |
[Plasma clotting system in neoplastic diseases].
Topics: Animals; Arginine; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Disseminated Intravascular Coagulation; Humans; Neoplasms; Platelet Aggregation; Thrombophlebitis; Thrombosis | 1976 |
Overproduction of nitric oxide in cytokine-mediated and septic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cytokines; Humans; Interleukin-2; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1992 |
NO synthases: mechanism of activation, identity of NOX and expression in human cells.
Topics: Adjuvants, Immunologic; Amino Acid Oxidoreductases; Animals; Arginine; Enzyme Activation; Humans; Neoplasms; Nitric Oxide Synthase; Nitrogen Oxides; Parasites | 1991 |
Future prospects for adjunctive therapy: pharmacologic and nutritional approaches to immune system modulation.
Topics: Animals; Arginine; Autoimmune Diseases; Humans; Immunity; Infections; Neoplasms; Nutritional Physiological Phenomena; Transplantation Immunology | 1990 |
Dietary immunomodulation: beneficial effects on oncogenesis and tumor growth.
Topics: Animals; Arginine; Dietary Fats; Humans; Immunity; Neoplasms | 1990 |
[Mechanisms of macrophage activation and macrophage-mediated tumoricidal activity].
Topics: Arginine; Cytotoxicity, Immunologic; Humans; Interferon-gamma; Macrophage Activation; Macrophages; Neoplasms; Signal Transduction; Tumor Necrosis Factor-alpha | 1989 |
Tumour-associated hormonal products.
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Arginine; Biliary Tract Diseases; Bronchial Neoplasms; Carcinoma; Chorionic Gonadotropin; Colonic Neoplasms; Cushing Syndrome; Erythropoietin; Female; Follicle Stimulating Hormone; Growth Hormone; Gynecomastia; Hormones, Ectopic; Humans; Hypercalcemia; Lactation Disorders; Lung Neoplasms; Luteinizing Hormone; Models, Biological; Neoplasms; Paraganglioma; Paraneoplastic Endocrine Syndromes; Polycythemia; Pregnancy; Prolactin; Thyroid Neoplasms; Vasopressins | 1974 |
[Regulation of DNA biosynthesis and cell division].
Topics: Arginine; Carbon Isotopes; Cell Division; Cell Membrane; DNA; DNA, Bacterial; Electrophoresis; Escherichia coli; Leucine; Neoplasms; Peptide Hydrolases; Proteins; Temperature; Thymine; Triazines; Trypsin | 1971 |
Pulmonary complications of novel antineoplastic agents for solid tumors.
Topics: Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bevacizumab; Deoxycytidine; Doxorubicin; Epirubicin; Etoposide; Everolimus; Gemcitabine; Humans; Lung; Lung Diseases; Mitoxantrone; Neoplasms; Pneumonia; Pyrimidines; Risk Factors; Sirolimus; Teniposide; Trastuzumab | 2008 |
[New antineoplastic agents, their value and use].
Topics: Aminacrine; Antineoplastic Agents; Aspartic Acid; Cisplatin; Etoposide; Humans; Ifosfamide; Interferons; Medroxyprogesterone; Medroxyprogesterone Acetate; Methyltestosterone; Neoplasms; Phosphonoacetic Acid; Razoxane; Tamoxifen; Teniposide; Vinca Alkaloids | 1982 |
Teniposide: a review of 12 years of experience.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide | 1984 |
The podophyllotoxin derivatives VP16-213 and VM26.
Topics: Animals; Chemical Phenomena; Chemistry; Drug Therapy, Combination; Etoposide; Humans; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
VM26: phase I and II studies.
Topics: Drug Evaluation; Humans; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
Teniposide: overview of its therapeutic potential in adult cancers.
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Etoposide; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma, Kaposi; Teniposide | 1994 |
Schedule-dependent topoisomerase II-inhibiting drugs.
Topics: Amsacrine; Antibiotics, Antineoplastic; Antineoplastic Agents; Cell Cycle; Clinical Trials, Phase I as Topic; DNA Repair; Drug Administration Schedule; Etoposide; Humans; Metabolic Clearance Rate; Neoplasms; Teniposide; Topoisomerase II Inhibitors | 1994 |
Epipodophyllotoxins in the treatment of childhood cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Etoposide; Humans; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Second Primary; Neuroblastoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 1994 |
Clinical pharmacokinetics and pharmacodynamics of epipodophyllotoxins.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Etoposide; Humans; Leukemia; Neoplasms; Neoplasms, Second Primary; Teniposide; Topoisomerase II Inhibitors | 1993 |
[DNA topoisomerases targeting anticancer agents and mechanism for acquirement of drug resistance].
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Etoposide; Humans; Irinotecan; Mutation; Neoplasms; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1997 |
Etoposide: four decades of development of a topoisomerase II inhibitor.
Topics: Administration, Oral; Anthracyclines; Antineoplastic Agents, Phytogenic; Etoposide; Humans; Mitoxantrone; Neoplasms; Technology, Pharmaceutical; Teniposide; Topoisomerase II Inhibitors | 1998 |
DNA topoisomerase II inhibitors.
Topics: Amsacrine; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Etoposide; Evidence-Based Medicine; Humans; Intestinal Absorption; Mitoxantrone; Neoplasms; Nucleic Acid Synthesis Inhibitors; Research Design; Risk Factors; Teniposide; Tissue Distribution; Topoisomerase II Inhibitors | 2000 |
Investigational drugs under study by the United States National Cancer Institute.
Topics: Acrylates; Alkylating Agents; Ancitabine; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Chemical Phenomena; Chemistry; Chromomycins; Cisplatin; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Humans; Ifosfamide; Leukemia L1210; Mice; Mitosis; National Institutes of Health (U.S.); Neoplasms; Neoplasms, Experimental; Razoxane; Tegafur; Teniposide; United States | 1976 |
Pharmacology of antitumor agents from higher plants.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Camptothecin; Carcinoma, Squamous Cell; Chemical Phenomena; Chemistry; Etoposide; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Lymphoid; Maytansine; Melanoma; Naphthoquinones; Nasopharyngeal Neoplasms; Neoplasms; Neoplasms, Experimental; Phenanthrenes; Structure-Activity Relationship; Teniposide; Vinblastine; Vincristine | 1976 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Hypersensitivity reactions.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Aziridines; Benzoquinones; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide; Cytarabine; Dacarbazine; Drug Hypersensitivity; Etoposide; Fluorouracil; Humans; Ifosfamide; Melphalan; Methotrexate; Mitomycins; Neoplasms; Paclitaxel; Pentostatin; Procarbazine; Teniposide | 1992 |
Teniposide in adult solid tumors: a historical perspective.
Topics: Adult; Animals; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Neoplasms; Teniposide | 1992 |
Disposition of antineoplastic agents in the very young child.
Topics: Age Factors; Antineoplastic Agents; Blood Proteins; Child; Child, Preschool; Doxorubicin; Etoposide; Humans; Infant; Infant, Newborn; Liver; Mercaptopurine; Methotrexate; Neoplasms; Nervous System; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Teniposide | 1992 |
Podophyllotoxin derivatives.
Topics: Animals; Drug Interactions; Drug Resistance; Etoposide; Humans; Neoplasms; Teniposide | 1991 |
13 trial(s) available for arginine and Neoplasms
| Article | Year |
|---|---|
Arginase-1 targeting peptide vaccine in patients with metastatic solid tumors - A phase I trial.
Topics: Arginase; Arginine; Cancer Vaccines; Humans; Leukocytes, Mononuclear; Neoplasms; Peptides; Tumor Microenvironment; Vaccines, Subunit | 2022 |
Topics: Adipose Tissue, White; Adult; Aged; Air Pollutants; Animals; Anti-Inflammatory Agents; Arginine; bcl-2-Associated X Protein; Biofuels; Biological Products; Blood Glucose; Breast Neoplasms; Caspases; CD36 Antigens; Cell Communication; Cell Proliferation; Cell Survival; Cooking; Cross-Sectional Studies; Databases, Factual; Diabetes Mellitus, Type 2; Diphtheria Toxin; Double-Blind Method; Exenatide; Extracellular Polymeric Substance Matrix; Feasibility Studies; Female; Filgrastim; Fruit; Galactose; Gene Deletion; Gene Knockdown Techniques; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Glucose; Glycated Hemoglobin; Hematopoietic Stem Cell Mobilization; Household Articles; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Lung; Lymphoma; Male; Metals, Heavy; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Nanoparticles; Neoplasms; Obesity; Obstetrics; Odds Ratio; Oxygen; Peripheral Blood Stem Cell Transplantation; Photochemotherapy; Plant Extracts; Polyethylene Glycols; Polyglutamic Acid; Porosity; Postprandial Period; Prospective Studies; Quality of Life; Receptors, Glucagon; Receptors, LDL; Receptors, Somatostatin; Registries; Rhodophyta; Rhodotorula; Risk Factors; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Somatostatin; Stilbenes; Terminalia; Treatment Outcome; United States; Venoms | 2021 |
Arginine, glutamine, and fish oil supplementation in cancer patients treated with concurrent chemoradiotherapy: A randomized control study.
Topics: Arginine; Chemoradiotherapy; Dietary Supplements; Female; Fish Oils; Glutamine; Hematologic Diseases; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasms; Patient Compliance; Severity of Illness Index; Treatment Outcome | 2020 |
Phase I Trial of Arginine Deprivation Therapy with ADI-PEG 20 Plus Docetaxel in Patients with Advanced Malignant Solid Tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arginine; Docetaxel; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydrolases; Male; Neoplasm Staging; Neoplasms; Polyethylene Glycols; Taxoids; Treatment Outcome | 2015 |
A randomized, double-blind, placebo-controlled trial of a beta-hydroxyl beta-methyl butyrate, glutamine, and arginine mixture for the treatment of cancer cachexia (RTOG 0122).
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Arginine; Cachexia; Dietary Supplements; Double-Blind Method; Drug Therapy, Combination; Female; Glutamine; Humans; Male; Middle Aged; Neoplasms; Placebos; Plethysmography; Quality of Life; Statistics, Nonparametric; Treatment Outcome; Valerates | 2008 |
Metabolic and immune effects of dietary arginine, glutamine and omega-3 fatty acids supplementation in immunocompromised patients.
Topics: Adult; Arginine; Burns; CD4-CD8 Ratio; Dietary Supplements; Enteral Nutrition; Fatty Acids, Omega-3; Female; Glutamine; Humans; Immunocompromised Host; Immunoglobulins; Lymphocyte Count; Male; Middle Aged; Neoplasms; Nutritional Status; Phenotype; Prospective Studies; Treatment Outcome; Wounds and Injuries | 1998 |
Reversal of cancer-related wasting using oral supplementation with a combination of beta-hydroxy-beta-methylbutyrate, arginine, and glutamine.
Topics: Aged; Arginine; Body Composition; Cachexia; Dietary Supplements; Double-Blind Method; Drug Combinations; Female; Glutamine; Humans; Male; Middle Aged; Muscle, Skeletal; Neoplasms; Treatment Outcome; Valerates | 2002 |
[New antineoplastic drugs of the podophyllotoxin derivative group].
Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1983 |
Teniposide: a review of 12 years of experience.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide | 1984 |
Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.
Topics: Adult; Aged; Alanine Transaminase; Alkenes; Antibiotics, Antineoplastic; Aspartate Aminotransferases; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Female; Half-Life; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Polyenes; Pyrones; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1999 |
Phase II study of VM-26 in acute leukemia, neuroblastoma, and other refractory childhood malignancies: a report from the Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Child; Clinical Trials as Topic; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Neoplasms; Neuroblastoma; Podophyllotoxin; Remission, Spontaneous; Teniposide | 1979 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Absolute bioavailability and pharmacokinetics of oral teniposide.
Topics: Absorption; Administration, Oral; Adult; Aged; Biological Availability; Clinical Trials, Phase I as Topic; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasms; Teniposide; Time Factors | 1992 |
229 other study(ies) available for arginine and Neoplasms
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.
Topics: Antineoplastic Agents; Brain Diseases; Click Chemistry; Dose-Response Relationship, Drug; Histidine; Humans; Large Neutral Amino Acid-Transporter 1; Molecular Structure; Neoplasms; Prodrugs; Structure-Activity Relationship; Triazoles; Tryptophan | 2019 |
Engineered Bacteria Increase L-Arginine to Improve Immunotherapy Response.
Topics: Arginine; Bacteria; Humans; Immunotherapy; Neoplasms | 2021 |
Near infrared light triggered ternary synergistic cancer therapy via L-arginine-loaded nanovesicles with modification of PEGylated indocyanine green.
Topics: Animals; Arginine; Cell Line, Tumor; Humans; Indocyanine Green; Mice; Mice, Nude; Nanoparticles; Neoplasms; Photochemotherapy; Photosensitizing Agents; Phototherapy; Polyethylene Glycols | 2022 |
Armet from whitefly saliva acts as an effector to suppress plant defences by targeting tobacco cystatin.
Topics: Animals; Arginine; Cystatins; Hemiptera; Mammals; Neoplasms; Nicotiana; Plants; Saliva | 2022 |
Mechanisms of selective monocyte targeting by liposomes functionalized with a cationic, arginine-rich lipopeptide.
Topics: Animals; Arginine; Autoimmune Diseases; Cations; Humans; Lipopeptides; Lipopolysaccharide Receptors; Liposomes; Mice; Monocytes; Neoplasms | 2022 |
Endocytosis Involved d-Oligopeptide of Tryptophan and Arginine Displays Ordered Nanostructures and Cancer Cell Stereoselective Toxicity by Autophagy.
Topics: Arginine; Autophagy; Cell Line, Tumor; Endocytosis; Humans; Nanostructures; Neoplasms; Oligopeptides; Tryptophan | 2022 |
Global analysis of protein arginine methylation.
Topics: Animals; Arginine; Methylation; Mice; Neoplasms; Protein Processing, Post-Translational; Proteins | 2021 |
Solvation, Cancer Cell Photoinactivation and the Interaction of Chlorin Photosensitizers with a Potential Passive Carrier Non-Ionic Surfactant Tween 80.
Topics: Arginine; Excipients; Galactose; Humans; Lipids; Micelles; Neoplasms; Photosensitizing Agents; Polysorbates; Porphyrins; Pulmonary Surfactants; Surface-Active Agents | 2022 |
The association between symmetric dimethylarginine concentrations and various neoplasms in dogs and cats.
Topics: Animals; Arginine; Biomarkers; Case-Control Studies; Cat Diseases; Cats; Dog Diseases; Dogs; Neoplasms; Retrospective Studies | 2022 |
A peptoid-based inhibitor of protein arginine methyltransferase 1 (PRMT1) induces apoptosis and autophagy in cancer cells.
Topics: Apoptosis; Arginine; Autophagy; Humans; Neoplasms; Peptoids; Protein-Arginine N-Methyltransferases; Repressor Proteins | 2022 |
Arginine methylation of MTHFD1 by PRMT5 enhances anoikis resistance and cancer metastasis.
Topics: Anoikis; Arginine; Formate-Tetrahydrofolate Ligase; Humans; Methylation; Methylenetetrahydrofolate Dehydrogenase (NADP); Minor Histocompatibility Antigens; Neoplasms; Protein-Arginine N-Methyltransferases | 2022 |
Reactive oxygen species activated by mitochondria-specific camptothecin prodrug for enhanced chemotherapy.
Topics: Antineoplastic Agents; Arginine; Camptothecin; Cell Line, Tumor; Humans; Lactones; Lysine; Mitochondria; Neoplasms; Prodrugs; Reactive Oxygen Species; Water | 2022 |
PRMT5 activates AKT via methylation to promote tumor metastasis.
Topics: Arginine; Cell Line, Tumor; Humans; Methylation; Neoplasms; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins c-akt | 2022 |
Integrated Transcriptome and Metabolomic Analysis Reveal Anti-Angiogenic Properties of Disarib, a Novel Bcl2-Specific Inhibitor.
Topics: Animals; Antineoplastic Agents; Arginine; Indoles; Mice; Neoplasms; Neovascularization, Pathologic; Oleic Acid; Thiadiazoles; Transcriptome | 2022 |
Platinum-based nanocomposites loaded with MTH1 inhibitor amplify oxidative damage for cancer therapy.
Topics: Arginine; Aspartic Acid; Catalase; Cell Line, Tumor; Glycine; Humans; Hydrogen Peroxide; Liposomes; Metal Nanoparticles; Nanocomposites; Nanoparticles; Neoplasms; Nucleotides; Oligopeptides; Oxidative Stress; Oxygen; Photochemotherapy; Photosensitizing Agents; Platinum; Reactive Oxygen Species; Silicon Dioxide; Singlet Oxygen | 2022 |
Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile.
Topics: Arginine; Genes, ras; Humans; Ligands; Mutation; Neoplasms; Proto-Oncogene Proteins p21(ras) | 2022 |
Reactive oxygen species-responsive branched poly (β-amino ester) with robust efficiency for cytosolic protein delivery.
Topics: Arginine; Boronic Acids; Esters; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Nitrogen; Polymers; Reactive Oxygen Species; Saporins | 2022 |
An IGF-1R-mTORC1-SRPK2 signaling Axis contributes to FASN regulation in breast cancer.
Topics: Arginine; Cell Line, Tumor; Fatty Acid Synthases; Insulin-Like Growth Factor I; Mechanistic Target of Rapamycin Complex 1; Neoplasms; Protein Kinases; Protein Serine-Threonine Kinases; RNA; RNA, Messenger; Serine | 2022 |
The Structural Effects of Phosphorylation of Protein Arginine Methyltransferase 5 on Its Binding to Histone H4.
Topics: Adaptor Proteins, Signal Transducing; Arginine; Histones; Humans; Neoplasms; Nucleosomes; Phosphorylation; Protein Binding; Protein-Arginine N-Methyltransferases | 2022 |
Design, Synthesis and Biological Evaluation of Novel and Potent Protein Arginine Methyltransferases 5 Inhibitors for Cancer Therapy.
Topics: Arginine; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Humans; Neoplasms; Protein-Arginine N-Methyltransferases; Tetrahydroisoquinolines | 2022 |
Arginine methylation of BRD4 by PRMT2/4 governs transcription and DNA repair.
Topics: Arginine; Cell Cycle Proteins; Chromatin; DNA; DNA Repair; Humans; Intracellular Signaling Peptides and Proteins; Neoplasms; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Transcription Factors | 2022 |
Dynamic tagging to drive arginine nano-assembly to metabolically potentiate immune checkpoint blockade therapy.
Topics: Animals; Arginine; Cell Line, Tumor; Immune Checkpoint Inhibitors; Immunotherapy; Mice; Neoplasms; Tumor Microenvironment | 2023 |
Unraveling the Structural Changes in the DNA-Binding Region of Tumor Protein p53 (
Topics: Arginine; Codon; DNA; Humans; Mutation; Neoplasms; Protein Binding; Tumor Suppressor Protein p53 | 2022 |
Discovery of non-boronic acid Arginase 1 inhibitors through virtual screening and biophysical methods.
Topics: Arginase; Arginine; Boronic Acids; Enzyme Inhibitors; Humans; Models, Molecular; Neoplasms | 2023 |
An L-arginine-functionalized pillar[5]arene-based supramolecular photosensitizer for synergistically enhanced cancer therapeutic effectiveness.
Topics: Arginine; Calixarenes; Humans; Micelles; Neoplasms; Photosensitizing Agents; Quaternary Ammonium Compounds | 2023 |
Serum Copeptin in Cardiooncology Practice: Review of Pathophysiological and Clinical Implications.
Topics: Antineoplastic Agents; Arginine; Biomarkers; Cardiotoxicity; Echocardiography; Glycopeptides; Heart Injuries; Humans; Neoplasms | 2023 |
Ultrasound-Induced Piezocatalysis Triggered NO Generation for Enhanced Hypoxic Tumor Therapy.
Topics: Arginine; Cell Line, Tumor; Humans; Hydrogen Peroxide; Hypoxia; Nanoparticles; Neoplasms; Photochemotherapy; Reactive Oxygen Species; Tumor Microenvironment | 2023 |
Protein Arginine Methyltransferase 5 (PRMT5) Mutations in Cancer Cells.
Topics: Arginine; Artificial Intelligence; Histones; Humans; Mutation; Neoplasms; Protein-Arginine N-Methyltransferases | 2023 |
Defects in intratumoral arginine metabolism attenuate the replication and therapeutic efficacy of oncolytic myxoma virus.
Topics: Arginine; Citrulline; Humans; Myxoma virus; Neoplasms; Oncolytic Viruses | 2023 |
Research Progress on Small-molecule Inhibitors of Protein Arginine Methyltransferase 5 (PRMT5) for Treating Cancer.
Topics: Arginine; Cell Line, Tumor; Enzyme Inhibitors; Humans; Neoplasms; Protein-Arginine N-Methyltransferases | 2023 |
L-Arginine self-delivery supramolecular nanodrug for NO gas therapy.
Topics: Apoptosis; Arginine; Cell Line, Tumor; Humans; Hydrogen Peroxide; Nanoparticles; Neoplasms; Tumor Microenvironment | 2023 |
A novel self-assembled nucleobase-nanofiber platform of CDN to activate the STING pathway for synergistic cancer immunotherapy.
Topics: Animals; Arginine; Immunotherapy; Mice; Nanofibers; Neoplasms; Thymine | 2023 |
A double-gain theranostic nanoplatform based on self-supplying H
Topics: Arginine; Cell Line, Tumor; Glutathione; Humans; Hydrogen Peroxide; Nanocomposites; Neoplasms; Nitric Oxide; Precision Medicine | 2024 |
[Bacteria engineered to produce L-arginine potentiate cancer immunotherapy].
Topics: Arginine; Bacteria; Humans; Immunotherapy; Neoplasms | 2023 |
Molecular characteristics and clinical implications of serine/arginine-rich splicing factors in human cancer.
Topics: Alternative Splicing; Arginine; Humans; Neoplasms; Serine; Serine-Arginine Splicing Factors | 2023 |
Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.
Topics: Amino Acid Substitution; Arginine; Calmodulin-Binding Proteins; Carcinogenesis; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Mutation; Neoplasms; Nerve Tissue Proteins; Protein Kinase Inhibitors; Protein Phosphatase 2; Recombinant Proteins; Transfection; Tyrosine; Xenograft Model Antitumor Assays | 2020 |
Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns.
Topics: 5' Flanking Region; Amino Acid Substitution; Arginine; Binding Sites; Catalytic Domain; CpG Islands; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; HCT116 Cells; Histidine; Humans; Mutation, Missense; Neoplasms; Substrate Specificity | 2019 |
Tailoring Synthetic Melanin Nanoparticles for Enhanced Photothermal Therapy.
Topics: Animals; Arginine; Female; Humans; Hyperthermia, Induced; Melanins; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Phototherapy | 2019 |
Helix Self-Assembly Behavior of Amino Acid-Modified Camptothecin Prodrugs and Its Antitumor Effect.
Topics: Animals; Antineoplastic Agents; Arginine; Camptothecin; Carbon; Cell Line, Tumor; Cisplatin; Drug Delivery Systems; Female; Humans; Mice; Nanofibers; Neoplasms; Prodrugs; Solubility | 2020 |
Indospicine combined with arginine deprivation triggers cancer cell death via caspase-dependent apoptosis.
Topics: Apoptosis; Arginase; Arginine; Cell Line, Tumor; Cell Survival; Humans; Neoplasms; Norleucine; Protein Biosynthesis; Signal Transduction; Substrate Specificity | 2021 |
High-Throughput Fluorescence-Based Activity Assay for Arginase-1.
Topics: Arginase; Arginine; Enzyme Inhibitors; Fluorescence; High-Throughput Screening Assays; Humans; Neoplasms; Ornithine; T-Lymphocytes | 2020 |
Supplementation of l-arginine boosts the therapeutic efficacy of anticancer chemoimmunotherapy.
Topics: Amino Acids; Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; Arginine; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cyclophosphamide; Dietary Supplements; Dose-Response Relationship, Drug; Drug Synergism; Female; Flow Cytometry; Mice; Myeloid-Derived Suppressor Cells; Neoplasms; T-Lymphocyte Subsets | 2020 |
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Topics: Apoptosis; Arginine; Autophagy; Cell Line, Tumor; Chromatin; Cytosol; Ferritins; Histones; Humans; Hydrolases; Mitochondria; Neoplasms; Polyethylene Glycols | 2020 |
Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Immunological; Arginine; Biomarkers; Cells, Cultured; Chromatography, Liquid; Drug Monitoring; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Heterogeneous Nuclear Ribonucleoprotein A1; Humans; Leukocytes, Mononuclear; Mass Spectrometry; Methylation; Mice; Molecular Targeted Therapy; Neoplasms; Protein-Arginine N-Methyltransferases; Repressor Proteins; Substrate Specificity | 2020 |
ICG/l-Arginine Encapsulated PLGA Nanoparticle-Thermosensitive Hydrogel Hybrid Delivery System for Cascade Cancer Photodynamic-NO Therapy with Promoted Collagen Depletion in Tumor Tissues.
Topics: Animals; Arginine; Cell Line, Tumor; Cell Proliferation; Collagen; Drug Delivery Systems; Female; Hydrogels; Indocyanine Green; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasms; Nitric Oxide; Photochemotherapy; Photosensitizing Agents; Phototherapy; Polyesters; Polyethylene Glycols; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Microenvironment | 2021 |
Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting.
Topics: Animals; Arginine; Cachexia; Female; Heterografts; Humans; Male; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Muscle Proteins; Neoplasms; omega-N-Methylarginine | 2020 |
A Multifunctional Nanovaccine based on L-Arginine-Loaded Black Mesoporous Titania: Ultrasound-Triggered Synergistic Cancer Sonodynamic Therapy/Gas Therapy/Immunotherapy with Remarkably Enhanced Efficacy.
Topics: Arginine; Humans; Immunotherapy; Neoplasms; Titanium | 2021 |
Comprehensive characterization of protein-protein interactions perturbed by disease mutations.
Topics: Arachidonate 5-Lipoxygenase; Arginine; Computational Biology; Disease; Genome, Human; Histones; Humans; Mutation; Neoplasms; Pharmacogenomic Testing; Proprotein Convertase 9; Protein Interaction Maps; Receptors, LDL; Reproducibility of Results; rho Guanine Nucleotide Dissociation Inhibitor alpha; rhoA GTP-Binding Protein; Serine | 2021 |
Effect of dapagliflozin and/or L-arginine on solid tumor model in mice: The interaction between nitric oxide, transforming growth factor-beta 1, autophagy, and apoptosis.
Topics: Animals; Apoptosis; Arginine; Autophagy; Benzhydryl Compounds; Glucosides; Male; Mice; Neoplasms; Nitric Oxide; Transforming Growth Factor beta1; Transforming Growth Factors | 2021 |
Targeting a neoantigen derived from a common
Topics: Alleles; Animals; Antibodies, Bispecific; Antibodies, Neoplasm; Antigens, Neoplasm; Arginine; Chlorocebus aethiops; COS Cells; Female; HEK293 Cells; Histidine; HLA-A2 Antigen; Humans; Immunization, Passive; Jurkat Cells; Lymphocyte Activation; Mice, Inbred NOD; Mutation; Neoplasms; T-Lymphocytes; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays | 2021 |
Immunomodulation of Tumor Microenvironment by Arginine-Loaded Iron Oxide Nanoparticles for Gaseous Immunotherapy.
Topics: Acrylic Resins; Animals; Arginine; Gases; Humans; Immunotherapy; Macrophages; Magnetite Nanoparticles; Mice; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; Tumor Microenvironment; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays | 2021 |
Chromatin accessibility governs the differential response of cancer and T cells to arginine starvation.
Topics: Animals; Arginine; Chromatin; Humans; Immune Evasion; Neoplasms; T-Lymphocytes | 2021 |
Is there a link between the prevalence of cardiovascular disease, diabetes, kidney disease, chronic obstructive pulmonary disease and malignancies and the severity of COVID-19 within the BAME population?
Topics: Arginine; Cardiovascular Diseases; Comorbidity; COVID-19; Diabetes Mellitus; Humans; Kidney Diseases; Neoplasms; Prevalence; Pulmonary Disease, Chronic Obstructive; Risk Factors; SARS-CoV-2 | 2021 |
Improving selective targeting to cancer-associated fibroblasts by modifying liposomes with arginine based materials.
Topics: Arginine; Cancer-Associated Fibroblasts; Cell Line, Tumor; Doxorubicin; Drug Delivery Systems; Fluorescein; Liposomes; Neoplasms | 2022 |
Bioreducible, arginine-rich polydisulfide-based siRNA nanocomplexes with excellent tumor penetration for efficient gene silencing.
Topics: Arginine; Cell Line, Tumor; Gene Silencing; Humans; Neoplasms; RNA Interference; RNA, Small Interfering | 2021 |
Topics: Antineoplastic Agents; Arginine; Binding Sites; Cell Movement; Cell Proliferation; Computer Simulation; Drug Design; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Glyceric Acids; Humans; Ligands; Medicine, Chinese Traditional; Molecular Docking Simulation; Neoplasms; Phosphoglycerate Mutase; Protein Binding | 2021 |
Mutations in Cancer Cause Gain of Cysteine, Histidine, and Tryptophan at the Expense of a Net Loss of Arginine on the Proteome Level.
Topics: Amino Acid Substitution; Arginine; Cell Line, Tumor; Codon, Nonsense; Cysteine; Histidine; Humans; Neoplasms; Proteome; Tryptophan; Tumor Suppressor Protein p53 | 2017 |
The Horizon in Cardio-Oncology: "You Are Only as Good as Your Endothelium".
Topics: Arginine; Breast Neoplasms; Endothelium; Heart Diseases; Humans; Neoplasms; Nitric Oxide | 2017 |
Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Topics: Animals; Arginine; Calcium; Cell Membrane; Drosophila melanogaster; Genomics; HCT116 Cells; HEK293 Cells; Humans; Ion Channel Gating; Molecular Dynamics Simulation; Muscular Diseases; Mutation; Neoplasm Proteins; Neoplasms; ORAI1 Protein; Patch-Clamp Techniques; Protein Structure, Secondary; Stromal Interaction Molecule 1; Transcriptional Activation | 2017 |
Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment.
Topics: Animals; Arginase; Arginine; Cell Line, Tumor; Cell Proliferation; Female; Hep G2 Cells; Humans; K562 Cells; Male; Mice; Myeloid Cells; Neoplasms; Pyrrolidines; Small Molecule Libraries; T-Lymphocytes; Tumor Microenvironment; Up-Regulation; Xenograft Model Antitumor Assays | 2017 |
Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies.
Topics: Algorithms; Animals; Antineoplastic Agents; Arginine; Fluorouracil; Humans; Immune Tolerance; Immunity; Killer Cells, Natural; Lymphoma; Mice; Models, Immunological; Myeloid-Derived Suppressor Cells; Neoplasms; T-Lymphocytes, Cytotoxic | 2018 |
Elevated mitochondrial SLC25A29 in cancer modulates metabolic status by increasing mitochondria-derived nitric oxide.
Topics: Animals; Arginine; Carnitine Acyltransferases; Disease Progression; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Glycolysis; HeLa Cells; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mitochondria; Mitochondrial Proteins; Neoplasm Transplantation; Neoplasms; Nitric Oxide; Up-Regulation | 2018 |
Design and Development of Polysaccharide-Doxorubicin-Peptide Bioconjugates for Dual Synergistic Effects of Integrin-Targeted and Cell-Penetrating Peptides for Cancer Chemotherapy.
Topics: Animals; Antibiotics, Antineoplastic; Arginine; Carboxymethylcellulose Sodium; Cell Line, Tumor; Cell-Penetrating Peptides; Chickens; Doxorubicin; Drug Carriers; Drug Delivery Systems; HEK293 Cells; Humans; Integrins; Neoplasms; Oligopeptides | 2018 |
Development of novel affinity reagents for detecting protein tyrosine phosphorylation based on superbinder SH2 domain in tumor cells.
Topics: Arginine; Cell Line, Tumor; Fluorescent Antibody Technique; Green Fluorescent Proteins; Humans; Immunoblotting; Microscopy, Fluorescence; Neoplasms; Optical Imaging; Phosphorylation; src Homology Domains; src-Family Kinases; Tyrosine | 2018 |
Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide-Generating Agents Improves the Therapeutic Effects of Nanomedicines.
Topics: Animals; Antineoplastic Agents; Arginine; Disease Models, Animal; Doxorubicin; Female; Hydroxyurea; Macromolecular Substances; Male; Mice; Nanomedicine; Nanoparticles; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Permeability; Rats, Sprague-Dawley | 2018 |
Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis.
Topics: Amino Acid Substitution; Arginine; Caspase 6; Humans; Hydrolysis; Mutation, Missense; Neoplasm Proteins; Neoplasms; Neurodegenerative Diseases; Protein Domains | 2019 |
Autophagy maintains tumour growth through circulating arginine.
Topics: Allografts; Animals; Arginase; Arginine; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carcinogenesis; Cell Proliferation; Dietary Supplements; Hepatocytes; Liver; Male; Mice; Neoplasm Transplantation; Neoplasms; Ornithine | 2018 |
Maintaining the tumour's diet.
Topics: Arginine; Autophagy; Diet; Humans; Neoplasms | 2019 |
Explosible nanocapsules excited by pulsed microwaves for efficient thermoacoustic-chemo combination therapy.
Topics: Animals; Arginine; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Liberation; Female; Humans; Hyperthermia, Induced; Mice; Mice, Inbred BALB C; Microscopy, Confocal; Microwaves; Nanocapsules; Neoplasms; Polymers; Skin; Survival Rate; Transplantation, Heterologous | 2019 |
A recurrent cancer-associated substitution in DNA polymerase ε produces a hyperactive enzyme.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; DNA; DNA Damage; DNA Polymerase II; DNA Repair Enzymes; DNA Replication; DNA-Directed DNA Polymerase; Genes, Fungal; Humans; Mutagenesis; Mutation; Mutation Rate; Neoplasms; Phenotype; Protein Domains; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2019 |
Host Control of Tumor Feeding: Autophagy Holds the Key.
Topics: Arginine; Autophagy; Humans; Neoplasms | 2019 |
Blood Circulation-Prolonging Peptides for Engineered Nanoparticles Identified via Phage Display.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Bacteriophage M13; Biological Transport; Cell Surface Display Techniques; Doxorubicin; Ferritins; Glycine; Humans; Nanoparticles; Neoplasms; Peptide Library; Peptides | 2019 |
Transport of cystine across xC
Topics: Alanine; Amino Acid Substitution; Amino Acid Transport System y+; Antiporters; Arginine; Binding Sites; Cystine; Humans; Molecular Dynamics Simulation; Neoplasms; Protein Transport | 2019 |
A Highly Effective π-π Stacking Strategy To Modify Black Phosphorus with Aromatic Molecules for Cancer Theranostics.
Topics: Arginine; Aspartic Acid; Glycine; Humans; Nanocomposites; Neoplasms; Peptides; Phosphorus; Phototherapy; Theranostic Nanomedicine | 2019 |
A light-facilitated drug delivery system from a pseudo-protein/hyaluronic acid nanocomplex with improved anti-tumor effects.
Topics: Animals; Antineoplastic Agents; Arginine; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Endocytosis; Female; Humans; Hyaluronic Acid; Light; Mice; Mice, Nude; Nanostructures; Neoplasms; Peptides; Tissue Distribution | 2019 |
Starvation in cancer cells: circulating arginine is good for cancer but bad for patients.
Topics: Animals; Antineoplastic Agents; Arginine; Autophagy; Humans; Neoplasms; Signal Transduction | 2019 |
Arginine Starvation and Docetaxel Induce c-Myc-Driven hENT1 Surface Expression to Overcome Gemcitabine Resistance in ASS1-Negative Tumors.
Topics: Animals; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Cell Membrane; Deoxycytidine; Disease Models, Animal; Docetaxel; Equilibrative Nucleoside Transporter 1; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Models, Biological; Neoplasms; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-myc; Xenograft Model Antitumor Assays | 2019 |
Modulation of CAT-2B-Mediated l-Arginine Uptake and Nitric Oxide Biosynthesis in HCT116 Cell Line Through Biological Activity of 4'-Geranyloxyferulic Acid Extract from Quinoa Seeds.
Topics: Anticarcinogenic Agents; Arginine; Cationic Amino Acid Transporter 2; Chenopodium quinoa; Coumaric Acids; HCT116 Cells; Humans; Inflammation; Neoplasms; Nitric Oxide; Oxidative Stress; Seeds | 2019 |
[Efficacy of AboundTM for hand-foot syndrome caused by capecitabine].
Topics: Aged; Antimetabolites, Antineoplastic; Arginine; Butyrates; Capecitabine; Deoxycytidine; Female; Fluorouracil; Glutamine; Hand-Foot Syndrome; Humans; Hydroxy Acids; Male; Middle Aged; Neoplasms | 2013 |
A preliminary report on the changes in the blood during malignancy, pregnancy, and injury.
Topics: Arginine; Blood Proteins; Female; Humans; Neoplasms; Pregnancy; Wounds and Injuries | 1951 |
Enhanced arginine methylation of programmed cell death 4 protein during nutrient deprivation promotes tumor cell viability.
Topics: Apoptosis Regulatory Proteins; Arginine; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Methylation; Neoplasm Proteins; Neoplasms; Phosphorylation; Protein-Arginine N-Methyltransferases; RNA-Binding Proteins; Up-Regulation | 2014 |
Evolution of histone 2A for chromatin compaction in eukaryotes.
Topics: Animals; Arginine; Cell Line, Tumor; Chromatin; Chromatin Assembly and Disassembly; Evolution, Molecular; Genome, Fungal; HEK293 Cells; Histones; Humans; Neoplasms; Nucleosomes; Protein Structure, Tertiary; Saccharomyces cerevisiae; Xenopus laevis | 2014 |
[Plasma amino acid profiling of "same symptom for different disease" in Uyghur medicine based on high-performance liquid chromatography].
Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography, High Pressure Liquid; Cystine; Humans; Isoleucine; Leucine; Medicine, Chinese Traditional; Neoplasms; Serine; Tyrosine; Valine | 2014 |
Pollution linked to lethal sea turtle tumours.
Topics: Animals; Arginine; Conservation of Natural Resources; Endangered Species; Environmental Exposure; Hawaii; Neoplasms; Rhodophyta; Turtles; Water Pollutants, Chemical | 2014 |
Arginine depletion by arginine deiminase does not affect whole protein metabolism or muscle fractional protein synthesis rate in mice.
Topics: Animals; Arginine; Hydrolases; Male; Mice; Mice, Inbred ICR; Muscle Proteins; Muscle, Skeletal; Neoplasms; Polyethylene Glycols | 2015 |
Evolving paradigms in the nutritional support of critically ill surgical patients.
Topics: Arginine; Burns; Cachexia; Critical Illness; Enteral Nutrition; Fish Oils; Gastrointestinal Tract; Glutamine; Humans; Infusions, Intravenous; Lipids; Microbiota; Multiple Organ Failure; Muscle, Skeletal; Neoplasms; Parenteral Nutrition; Perioperative Care; Protein-Energy Malnutrition; Stress, Physiological | 2015 |
p53-Encoding pDNA Purification by Affinity Chromatography for Cancer Therapy.
Topics: Alkalies; Animals; Arginine; Blotting, Western; Chlorocebus aethiops; Chromatography, Affinity; COS Cells; DNA; Electrophoresis, Agar Gel; Neoplasms; Plasmids; Tumor Suppressor Protein p53 | 2015 |
Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents.
Topics: Antineoplastic Agents; Arginine; Axl Receptor Tyrosine Kinase; Cell Death; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Hydrolases; Intercellular Signaling Peptides and Proteins; Molecular Targeted Therapy; Neoplasms; Polyethylene Glycols; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Signal Transduction | 2016 |
Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumors.
Topics: Alternative Splicing; Animals; Arginine; Binding Sites; Biomechanical Phenomena; Blotting, Western; Cattle; Cells, Cultured; Endothelial Cells; Extracellular Matrix; Fibronectins; Humans; Mice; Microscopy, Confocal; Neoplasms; Neovascularization, Pathologic; Phosphatidylinositol 3-Kinases; Protein Isoforms; Proto-Oncogene Proteins c-akt; rho-Associated Kinases; RNA Interference; Serine; Signal Transduction; Tumor Microenvironment; Vascular Endothelial Growth Factor A | 2015 |
Multi-small molecule conjugations as new targeted delivery carriers for tumor therapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Arginine; Cell Line, Tumor; Cell Survival; Chemical Phenomena; Drug Carriers; Female; Fluorescein-5-isothiocyanate; Folic Acid; Glutamic Acid; HEK293 Cells; Humans; Lethal Dose 50; Male; Mice; Mice, Nude; Molecular Weight; Neoplasms; Paclitaxel; Prodrugs; Solubility; Toxicity Tests, Acute; Xenograft Model Antitumor Assays | 2015 |
Twin-Arginine Translocation Peptide Conjugated Epirubicin-Loaded Nanoparticles for Enhanced Tumor Penetrating and Targeting.
Topics: Animals; Arginine; Cell Line, Tumor; Cell-Penetrating Peptides; Drug Carriers; Drug Delivery Systems; Epirubicin; Humans; Mice; Nanoparticles; Neoplasms; Rats; Tissue Distribution; Twin-Arginine-Translocation System | 2015 |
PRMT1 promotes mitosis of cancer cells through arginine methylation of INCENP.
Topics: Amino Acid Sequence; Arginine; Cell Line, Tumor; Chromosomal Proteins, Non-Histone; HEK293 Cells; HeLa Cells; Humans; Methylation; Mitosis; Molecular Sequence Data; Neoplasms; Protein-Arginine N-Methyltransferases; Repressor Proteins; Transfection | 2015 |
Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes.
Topics: Arginine; Epigenesis, Genetic; HEK293 Cells; Humans; Isocitrate Dehydrogenase; Models, Molecular; Molecular Structure; Mutant Proteins; Mutation; Neoplasms; Photochemical Processes | 2016 |
Mono-arginine Cholesterol-based Small Lipid Nanoparticles as a Systemic siRNA Delivery Platform for Effective Cancer Therapy.
Topics: Animals; Arginine; Cell Line, Tumor; Cholesterol; Female; Genetic Therapy; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; RNA, Small Interfering | 2016 |
Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20).
Topics: Animals; Arginine; Argininosuccinate Synthase; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Cell Hypoxia; Cell Line, Tumor; HCT116 Cells; Humans; Hydrolases; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mechanistic Target of Rapamycin Complex 1; Mice, SCID; Multiprotein Complexes; Neoplasms; Nitric Oxide; Nitric Oxide Synthase Type II; Perfusion; Polyethylene Glycols; TOR Serine-Threonine Kinases; Tumor Burden; Unfolded Protein Response; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2016 |
Combined factor IIa and Xa inhibitor therapy for thrombosis whilst on therapeutic anticoagulant.
Topics: Adult; Aged; Anticoagulants; Antithrombins; Arginine; Dabigatran; Factor Xa Inhibitors; Female; Heparin, Low-Molecular-Weight; Humans; Male; Middle Aged; Neoplasms; Pipecolic Acids; Pyrazoles; Pyridones; Recurrence; Rivaroxaban; Sulfonamides; Venous Thrombosis | 2016 |
Development of hematin conjugated PLGA nanoparticle for selective cancer targeting.
Topics: Arginine; Drug Delivery Systems; HeLa Cells; Hemin; Humans; Lactic Acid; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proton-Coupled Folate Transporter; Surface Properties | 2016 |
A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression.
Topics: A549 Cells; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenocarcinoma of Lung; Arginine; Breast Neoplasms; Carcinoma, Squamous Cell; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Lung Neoplasms; MCF-7 Cells; Methylation; Neoplasm Invasiveness; Neoplasms; Prognosis; Protein-Arginine N-Methyltransferases; Sequence Analysis, RNA; Transcription, Genetic; Transforming Growth Factor beta | 2017 |
Cisplatin-induced synthetic lethality to arginine-starvation therapy by transcriptional suppression of ASS1 is regulated by DEC1, HIF-1α, and c-Myc transcription network and is independent of ASS1 promoter DNA methylation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arginine; Argininosuccinate Synthase; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cell Survival; Cisplatin; DNA Methylation; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Homeodomain Proteins; Humans; Hydrolases; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Polyethylene Glycols; Promoter Regions, Genetic; Proteasome Inhibitors; Proto-Oncogene Proteins c-myc; RNA Interference; Signal Transduction; Time Factors; Transcription, Genetic; Transfection | 2016 |
Metabolism-Centric Trans-Omics.
Topics: Arginine; Humans; Neoplasms; T-Lymphocytes | 2017 |
Construction and in vitro evaluation of enzyme nanoreactors based on carboxymethyl chitosan for arginine deprivation in cancer therapy.
Topics: Arginine; Chitosan; Enzymes; Hydrolases; Micelles; Nanotechnology; Neoplasms | 2017 |
High gene delivery in tumor by intratumoral injection of tetraarginine-PEG lipid-coated protamine/DNA.
Topics: Animals; Arginine; DNA; Female; Genetic Therapy; HeLa Cells; Humans; Injections, Intralesional; Lipids; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oligopeptides; Particle Size; Polyethylene Glycols; Protamines; Transfection; Xenograft Model Antitumor Assays | 2008 |
Some aspects of the role of arginine and arginase in mouse carcinoma 63.
Topics: Animals; Arginase; Arginine; Humans; Mice; Neoplasms | 1947 |
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Amidinotransferases; Animals; Arginase; Arginine; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Creatine; Creatinine; Enzymes; Female; Gene Expression Regulation, Neoplastic; Guanidinoacetate N-Methyltransferase; Kidney; Liver; Membrane Transport Proteins; Methionine; Mice; Muscle, Skeletal; Neoplasms; Ornithine; Ornithine Decarboxylase; Sarcoma 180 | 2008 |
Modulators of arginine metabolism support cancer immunosurveillance.
Topics: Animals; Arginine; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Immunologic Factors; Immunologic Surveillance; Interferon-gamma; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myeloid Cells; Myelopoiesis; Neoplasms; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Spleen; Weight Loss | 2009 |
p53 methylation--the Arg-ument is clear.
Topics: Animals; Arginine; DNA Damage; Humans; Methylation; Neoplasms; Phosphorylation; Protein Methyltransferases; Protein Processing, Post-Translational; Tumor Suppressor Protein p53 | 2009 |
Effects of L-arginine and L-lysine mixtures on splenic sympathetic nerve activity and tumor proliferation.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arginine; Carcinoma; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Female; Humans; Immune Tolerance; Immunologic Factors; Killer Cells, Natural; Lysine; Male; Mice; Mice, Inbred BALB C; Neoplasms; Neuroimmunomodulation; Rats; Rats, Wistar; Spleen; Sympathetic Nervous System; Treatment Outcome | 2009 |
Enteral administration of alanyl-[2-(15)N]glutamine contributes more to the de novo synthesis of arginine than does intravenous infusion of the dipeptide in humans.
Topics: Arginine; Body Mass Index; Citrulline; Dipeptides; Enteral Nutrition; Female; Gastrointestinal Diseases; Glutamine; Humans; Infusions, Intravenous; Isotope Labeling; Male; Middle Aged; Neoplasms; Nitrogen Isotopes | 2009 |
Constructing bioactive peptides with pH-dependent activities.
Topics: Amino Acid Sequence; Animals; Arginine; Cell Death; Cell Line; Fluoresceins; Histidine; Humans; Hydrogen-Ion Concentration; Lysine; Mice; Mice, Nude; Micelles; Neoplasms; Peptides; Structure-Activity Relationship; Transplantation, Homologous | 2009 |
Arginine methylation regulates telomere length and stability.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Cell Line; Cell Proliferation; Cellular Senescence; Chromatin Immunoprecipitation; Humans; Methylation; Molecular Sequence Data; Neoplasms; Protein Binding; Protein Structure, Tertiary; Protein-Arginine N-Methyltransferases; Repressor Proteins; Structure-Activity Relationship; Telomere; Telomeric Repeat Binding Protein 2 | 2009 |
Missense polymorphisms of PTPRJ and PTPN13 genes affect susceptibility to a variety of human cancers.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers, Tumor; Case-Control Studies; Colorectal Neoplasms; Esophageal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Head and Neck Neoplasms; Humans; Incidence; Isoleucine; Japan; Lung Neoplasms; Male; Methionine; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide; Proline; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Risk Factors | 2010 |
The effect of surface modification of adenovirus with an arginine-grafted bioreducible polymer on transduction efficiency and immunogenicity in cancer gene therapy.
Topics: Adenoviridae; Animals; Arginine; Cations; Cell Death; Cell Line; Coxsackie and Adenovirus Receptor-Like Membrane Protein; Genetic Therapy; Humans; Immune Evasion; Light; Mice; Neoplasms; Polyamines; Polyethyleneimine; Receptors, Virus; Reproducibility of Results; Scattering, Radiation; Serum; Surface Properties; Transduction, Genetic | 2010 |
RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system.
Topics: Animals; Arginine; Chlorocebus aethiops; COS Cells; Genes, erbB-2; Genetic Therapy; Mice; Mice, Inbred BALB C; Neoplasms; Peptides; RNA Interference; RNA, Small Interfering | 2010 |
Arginine-arginase relationship in regeneration, repair and development of neoplasms.
Topics: Arginase; Arginine; Humans; Neoplasms; Regeneration; Wound Healing | 1946 |
Some aspects of the metabolism of arginine in malignant tissue.
Topics: Arginine; Neoplasms | 1946 |
Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers.
Topics: Anthracenes; Arginine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line, Tumor; DNA Replication; Enzyme-Linked Immunosorbent Assay; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasms; Nuclear Proteins; Oligonucleotide Array Sequence Analysis; Propane; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA, Small Interfering; Urinary Bladder Neoplasms | 2011 |
Simultaneous determination of l-citrulline and l-arginine in plasma by high performance liquid chromatography.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Case-Control Studies; Chromatography, High Pressure Liquid; Citrulline; Female; Humans; Indicators and Reagents; Limit of Detection; Male; Methods; Middle Aged; Neoplasms | 2010 |
Induction of apoptosis by gene transfer of human TRAIL mediated by arginine-rich intracellular delivery peptides.
Topics: Apoptosis; Arginine; Cell Line, Tumor; Drug Delivery Systems; Flow Cytometry; Genetic Therapy; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Neoplasms; Peptides; Plasmids; TNF-Related Apoptosis-Inducing Ligand | 2010 |
Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes.
Topics: Arginase; Arginine; Argininosuccinate Synthase; Citrulline; Epithelial Cells; Humans; Neoplasms; Ornithine; Ornithine Carbamoyltransferase; Tumor Cells, Cultured | 2010 |
Canavanine augments proapoptotic effects of arginine deprivation in cultured human cancer cells.
Topics: Apoptosis; Arginine; Canavanine; Cell Line; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Drug Therapy, Combination; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Neoplasms; Protein Binding | 2011 |
Enzymatic hydrolysis of benzoylarginineamide in normal and neoplastic tissues.
Topics: Arginine; Enzymes; Hydrolysis; Neoplasms | 1946 |
Immunohistochemical detection of arginine methylated proteins (MeRP) in archival tissues.
Topics: Antibodies; Antibody Specificity; Arginine; Immunohistochemistry; Methylation; Neoplasms; Paraffin Embedding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Proteins | 2010 |
Rapid evolution of arginine deiminase for improved anti-tumor activity.
Topics: Amino Acid Sequence; Antineoplastic Agents; Arginine; Bacterial Proteins; Directed Molecular Evolution; Enzyme Stability; Hydrolases; Kinetics; Models, Molecular; Molecular Sequence Data; Neoplasms; Pseudomonas; Sequence Alignment | 2011 |
Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polyethylenimine polyplex.
Topics: Animals; Arginine; beta-Galactosidase; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Therapy; Humans; Leucine; Lysine; Mice; Mice, Inbred BALB C; Neoplasms; Polyethyleneimine | 2011 |
Roles of protein arginine methylation in DNA damage signaling pathways is CARM1 a life-or-death decision point?
Topics: Arginine; Cell Survival; DNA Damage; DNA Methylation; Humans; Neoplasms; Protein-Arginine N-Methyltransferases; Signal Transduction | 2011 |
RNA interference of argininosuccinate synthetase restores sensitivity to recombinant arginine deiminase (rADI) in resistant cancer cells.
Topics: Antineoplastic Agents; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Cell Survival; Citrulline; Drug Resistance, Neoplasm; Gene Expression; HeLa Cells; Humans; Hydrolases; Neoplasms; Recombinant Proteins; RNA Interference; RNA, Small Interfering | 2011 |
FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development.
Topics: Abnormalities, Multiple; Alleles; Amino Acid Sequence; Animals; Arginine; Cell Cycle Proteins; Disease Models, Animal; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Humans; Lung; Mice; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Point Mutation; Pulmonary Alveoli; Sequence Alignment; Transforming Growth Factor beta; Ubiquitin-Protein Ligases | 2011 |
Enhanced gene expression in tumors after intravenous administration of arginine-, lysine- and leucine-bearing polypropylenimine polyplex.
Topics: Animals; Arginine; Female; Gene Expression; Humans; Leucine; Lysine; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Neoplasms; Polypropylenes | 2011 |
Differences in DNA condensation and release by lysine and arginine homopeptides govern their DNA delivery efficiencies.
Topics: Animals; Arginine; Biological Transport; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; DNA Packaging; DNA-Binding Proteins; DNA, Neoplasm; DNA, Viral; Gene Transfer Techniques; Genetic Vectors; Humans; Lysine; Molecular Weight; Neoplasms; Nucleic Acid Conformation; Oligopeptides; Particle Size; Peptides; Structure-Activity Relationship | 2011 |
Distinct transduction modes of arginine-rich cell-penetrating peptides for cargo delivery into tumor cells.
Topics: Animals; Arginine; Avidin; Biological Transport; Cell Line, Tumor; Cell Membrane; Cell-Penetrating Peptides; Drug Delivery Systems; Endocytosis; Fluorescein-5-isothiocyanate; Heparan Sulfate Proteoglycans; Humans; Mice; Molecular Weight; Neoplasms; Rats; Temperature; Time Factors | 2011 |
Arginine residues are more effective than lysine residues in eliciting the cellular uptake of onconase.
Topics: Amphibian Proteins; Animals; Antineoplastic Agents; Arginine; Humans; K562 Cells; Lysine; Models, Molecular; Neoplasms; Rana pipiens; Ribonucleases | 2011 |
Strategies for optimizing the serum persistence of engineered human arginase I for cancer therapy.
Topics: Animals; Arginase; Arginine; Cysteine; Female; Humans; Mice; Mice, Inbred BALB C; Neoplasms; Polyethylene Glycols | 2012 |
Photodynamic anticancer activities of water-soluble C(60) derivatives and their biological consequences in a HeLa cell line.
Topics: Antineoplastic Agents; Apoptosis; Arginine; Caspase 3; Catalase; Cell Survival; Folic Acid; Fullerenes; Glutathione Peroxidase; HeLa Cells; Humans; Light; Malondialdehyde; Membrane Potential, Mitochondrial; Neoplasms; Phenylalanine; Photochemotherapy; Reactive Oxygen Species; Superoxide Dismutase; Water | 2012 |
An arginine derivative contained nanostructure lipid carriers with pH-sensitive membranolytic capability for lysosomolytic anti-cancer drug delivery.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arginine; Cell Line, Tumor; Cell Membrane; Cell Survival; Cells, Cultured; Drug Carriers; Erythrocytes; Hemolysis; Humans; Hydrogen-Ion Concentration; Lipids; Lysosomes; Male; Mice; Nanoparticles; Neoplasms; Paclitaxel; Rats; Serum Albumin, Bovine; Tissue Distribution | 2012 |
T-ARG-eting E2F-1 growth control.
Topics: Animals; Apoptosis; Arginine; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Methylation; Mice; Neoplasms; Protein Methyltransferases; Protein-Arginine N-Methyltransferases; Tumor Suppressor Protein p53; Ubiquitination | 2012 |
The key role of IL-6-arginase cascade for inducing dendritic cell-dependent CD4(+) T cell dysfunction in tumor-bearing mice.
Topics: Animals; Arginase; Arginine; CD4-Positive T-Lymphocytes; Dendritic Cells; Female; Histocompatibility Antigens Class II; Interleukin-6; Lymphocyte Activation; Mice; Mice, Transgenic; Neoplasms; Signal Transduction | 2013 |
The codon 72 polymorphic variants of p53 have markedly different apoptotic potential.
Topics: Apoptosis; Arginine; Cell Line; Chaperonin 60; Codon; Fatty Acids, Unsaturated; Genes, p53; Genetic Variation; HSP70 Heat-Shock Proteins; Humans; Membrane Proteins; Mitochondria; Neoplasms; Polymorphism, Genetic; Proline; Suppression, Genetic; Transcriptional Activation; Tumor Suppressor Protein p53; Ubiquitin | 2003 |
Basic peptide system for efficient delivery of foreign genes.
Topics: Animals; Arginine; Biological Transport; Cell Line; DNA; Genetic Therapy; Humans; Neoplasms; Peptides; Proteoglycans; Thymidine Kinase; Transfection | 2003 |
Oncogenic mutations and packing defects in protein structure.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Arginine; Binding Sites; Glycine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Mutation; Neoplasms; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Proto-Oncogene Proteins p21(ras); Static Electricity; Tumor Suppressor Protein p53; Valine | 2003 |
The competitive effect of canavanine on utilization of arginine in growth of Walker carcinosarcoma 256 cells in vitro.
Topics: Amino Acids; Animals; Arginine; Canavanine; Carcinoma 256, Walker; In Vitro Techniques; Neoplasms | 1958 |
Effects of certain amino acid derivatives on microorganisms and sarcoma 180.
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Aspartic Acid; Lactobacillus; Neoplasms; Sarcoma 180 | 1958 |
Arginine uptake and arginase activity in Ehrlich ascites carcinoma cells.
Topics: Amidohydrolases; Arginase; Arginine; Ascites; Biochemical Phenomena; Carbohydrate Metabolism; Carbohydrates; Catabolite Repression; Glucose; Humans; Neoplasms | 1959 |
[Free arginine in tumors and tumor-bearing animals].
Topics: Animals; Arginine; Neoplasms; Neoplasms, Experimental | 1959 |
Suppression of uptake of L-arginine-U-14C into chromatographically separated cationic nuclear proteins of tissues of tumour-bearing rats by 5-bis (2-chloroethyl) aminouracil.
Topics: Animals; Arginine; Biochemical Phenomena; Cations; Neoplasms; Nuclear Proteins; Nucleoproteins; Rats; Uracil | 1961 |
Kinetics of incorporation of L-arginine-U-C14 into nuclear proteins of tumors and other tissues in vitro.
Topics: Arginine; Histones; In Vitro Techniques; Kinetics; Neoplasms; Nuclear Proteins; Nucleoproteins | 1960 |
[CLINICAL AND EXPERIMENTAL STUDIES ON CHANGES IN THE BODY FLUIDS IN CANCER].
Topics: Antineoplastic Agents; Arginine; Ascites; Aspartate Aminotransferases; Blood Chemical Analysis; Blood Proteins; Body Fluids; Cyclophosphamide; Glycoproteins; Mechlorethamine; Mitomycin; Mitomycins; Neoplasms; Neuraminic Acids; Pharmacology; Polarography; Rats; Research; Thiotepa | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
TRANSAMIDINASE ACTIVITIES IN VITRO OF KIDNEYS FROM TUMOR-BEARING MICE AND RATS FED DIETS SUPPLEMENTED WITH PROTEIN OR CERTAIN AMINO ACIDS.
Topics: Amidinotransferases; Amino Acids; Animals; Arginine; Blood Chemical Analysis; Carcinoma 256, Walker; Creatine; Creatinine; Diet; Dietary Proteins; Dietary Supplements; Glycine; In Vitro Techniques; Kidney; Mice; Neoplasms; Neoplasms, Experimental; Proteins; Rats; Research; Transferases; Urine | 1964 |
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research | 1964 |
[ROLE OF THE ARGININE-ARGINASE COMPLEX IN NORMAL AND ABNORMAL TISSUE GROWTH].
Topics: Arginase; Arginine; Growth; Humans; Neoplasms; Ornithine; Physiological Phenomena; Proteins; Ultraviolet Rays | 1963 |
CYTOPATHOGENIC MYCOPLASMAS ASSOCIATED WITH TWO HUMAN TUMORS. I. ISOLATION AND BIOLOGICAL ASPECTS.
Topics: Animals; Arginine; Culture Media; Fibroma; Hemangioma; Humans; Microbiology; Mycoplasma; Neoplasms; Neutralization Tests; Pharyngeal Neoplasms; Research; Tissue Culture Techniques; Vesicular Stomatitis; Vesicular stomatitis Indiana virus; Viral Interference | 1965 |
Incidence and distribution of argininosuccinate synthetase deficiency in human cancers: a method for identifying cancers sensitive to arginine deprivation.
Topics: Arginine; Argininosuccinate Synthase; Biopsy; Citrullinemia; Humans; Immunohistochemistry; Neoplasms; Pharmacogenetics; Tumor Cells, Cultured | 2004 |
Arg9-peptide facilitates the internalization of an anti-CEA immunotoxin and potentiates its specific cytotoxicity to target cells.
Topics: Arginine; Carcinoembryonic Antigen; Cell Line, Tumor; Cytotoxicity, Immunologic; Endocytosis; Humans; Immunotoxins; Neoplasms; Oligopeptides; Protein Transport; Recombinant Fusion Proteins | 2005 |
Arginine methylation of STAT1: a reassessment.
Topics: Arginine; Artifacts; DNA-Binding Proteins; Humans; Interferons; Methylation; Methyltransferases; Mutation; Neoplasms; Reproducibility of Results; STAT1 Transcription Factor; Trans-Activators | 2004 |
Plasma arginine concentrations are reduced in cancer patients: evidence for arginine deficiency?
Topics: Adult; Aged; Arginine; Breast Neoplasms; Case-Control Studies; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Neoplasms; Pancreatic Neoplasms; Weight Loss | 2005 |
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; beta-Galactosidase; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Separation; Cells, Cultured; Chromatin Immunoprecipitation; Codon; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Flow Cytometry; Homozygote; Humans; Luciferases; Microscopy, Fluorescence; Neoplasms; Oligonucleotides; Oxidative Stress; Polymorphism, Genetic; Proline; Propidium; Protein Isoforms; Transfection | 2005 |
Integrity and stability of the citrulline-arginine pathway in normal and tumour cell lines.
Topics: Animals; Arginine; Argininosuccinic Acid; Carbon Radioisotopes; Cell Division; Cells, Cultured; Citrulline; Cricetinae; Dogs; Humans; Mice; Neoplasms; Rats; Signal Transduction | 2005 |
Modulation of arginine metabolic pathways as the potential anti-tumor mechanism of recombinant arginine deiminase.
Topics: Adenocarcinoma; Arginine; Breast Neoplasms; Humans; Hydrolases; Lung Neoplasms; Neoplasms; Nitric Oxide; Nitric Oxide Synthase; Polyamines; Protein Biosynthesis; Tumor Cells, Cultured | 2006 |
PMS2 mutations in childhood cancer.
Topics: Adenosine Triphosphatases; Adolescent; Arginine; Astrocytoma; Cafe-au-Lait Spots; Child; Colonic Polyps; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Female; Founder Effect; Genetic Predisposition to Disease; Glioma; Humans; Leukemia, T-Cell; Lymphoma, B-Cell; Lymphoma, T-Cell; Male; Mismatch Repair Endonuclease PMS2; Mutation; Neoplasms; Neoplasms, Second Primary; Pakistan; Precursor Cell Lymphoblastic Leukemia-Lymphoma; United Kingdom | 2006 |
Mutational analysis of the p53 core domain L1 loop.
Topics: Alanine; Amino Acid Substitution; Arginine; Base Sequence; Binding Sites; DNA; DNA Mutational Analysis; Humans; Models, Molecular; Mutagenesis, Site-Directed; Mutation, Missense; Neoplasms; Nucleic Acid Conformation; Point Mutation; Protein Conformation; Protein Structure, Secondary; Reverse Transcriptase Polymerase Chain Reaction; Tumor Suppressor Protein p53 | 2006 |
L-arginine availability regulates T-lymphocyte cell-cycle progression.
Topics: Animals; Arginine; Cell Cycle; Cell Proliferation; Clonal Anergy; Cyclin D3; Cyclin-Dependent Kinases; Cyclins; Gene Expression Regulation; Humans; Mice; Mice, Knockout; Neoplasms; Protein Serine-Threonine Kinases; T-Lymphocytes | 2007 |
Conjugation of arginine-glycine-aspartic acid peptides to poly(ethylene oxide)-b-poly(epsilon-caprolactone) micelles for enhanced intracellular drug delivery to metastatic tumor cells.
Topics: Aldehydes; Arginine; Aspartic Acid; Cell Line, Tumor; Drug Delivery Systems; Glycine; Humans; Lactones; Micelles; Microscopy, Confocal; Microscopy, Fluorescence; Models, Chemical; Neoplasm Metastasis; Neoplasms; Peptides; Polyethylene Glycols | 2007 |
Polymorphism of dihydropyrimidine dehydrogenase (DPYD) Cys29Arg and risk of six malignancies in Japanese.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Asian People; Chi-Square Distribution; Cysteine; Dihydrouracil Dehydrogenase (NADP); Female; Gene Frequency; Genotype; Humans; Japan; Male; Middle Aged; Models, Biological; Neoplasms; Odds Ratio; Polymorphism, Genetic | 2005 |
TP53 codon 72 polymorphism in 12 populations of insular Southeast Asia and Oceania.
Topics: Amino Acid Substitution; Arginine; Asia, Southeastern; Codon; Gene Frequency; Genetic Predisposition to Disease; Humans; Neoplasms; Oceania; Polymorphism, Genetic; Population; Proline; Tumor Suppressor Protein p53 | 2007 |
Cancer immunology. Cancer's bulwark against immune attack: MDS cells.
Topics: Animals; Arginine; B-Lymphocytes; Cancer Vaccines; Cyclooxygenase 2; Humans; Immune Tolerance; Inflammation; Interleukin-1beta; Macrophages; Myeloid Cells; Neoplasms; Peroxynitrous Acid; Receptors, Antigen, T-Cell; T-Lymphocytes; Vascular Endothelial Growth Factor A | 2008 |
Inhibition of osteopontin dependent carcinogenesis.
Topics: Alkaloids; Antineoplastic Agents; Arginine; Humans; Neoplasms; Osteopontin; Oxazolidinones; Pipecolic Acids; Selenium; Sulfonamides | 2008 |
Aminoaciduria resulting from cycloleucine administration in man.
Topics: Amino Acids; Arginine; Cystinuria; Humans; Kidney Tubules; Lysine; Neoplasms; Ornithine | 1967 |
Antitumor therapy based on the use of an immune modulator, arginine butyrate and interferon.
Topics: Amniotic Fluid; Animals; Arginine; Butyrates; Cytoskeleton; Extracellular Matrix; Female; Humans; Immune System; Interferons; Mice; Mice, Inbred AKR; Neoplasms; Pregnancy; Propionibacterium acnes; Rats; Sarcoma 180 | 1984 |
Plasma somatostatin in normal subjects and in various diseases: increased levels in somatostatin-producing tumors.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Arginine; Calcitonin; Carcinoma; Diabetes Mellitus; Female; Humans; Liver Diseases; Male; Middle Aged; Neoplasms; Pheochromocytoma; Somatostatin; Thyroid Neoplasms | 1982 |
[Studies on platelet aggregation induced by human cultured carcinoma cell lines].
Topics: Arginine; Cell Line; Cells, Cultured; Female; Humans; Lung Neoplasms; Membrane Proteins; Microbial Collagenase; Neoplasms; Neoplastic Cells, Circulating; Neuraminidase; Pipecolic Acids; Platelet Aggregation; Stomach Neoplasms; Sulfonamides; Trypsin | 1984 |
Enzyme therapy: problems and solutions.
Topics: Animals; Arginine; Blood Coagulation Disorders; Enzyme Therapy; Enzymes; Enzymes, Immobilized; Erwinia; Escherichia coli; Fabry Disease; Folic Acid; gamma-Glutamyl Hydrolase; Gaucher Disease; Humans; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Metabolic Clearance Rate; Neoplasms; Poisoning; Ribonucleases; Urokinase-Type Plasminogen Activator | 1982 |
Nutritional pharmacology: effects of L-arginine on host defences, response to trauma and tumour growth.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Hemodynamics; Humans; Immune System; Immunity, Cellular; Macrophages; Neoplasms; Wound Healing | 1994 |
Screening for germ line p53 mutations in children with malignant tumors and a family history of cancer.
Topics: Adolescent; Adult; Alleles; Arginine; Base Sequence; Child; Child, Preschool; Exons; Family Health; Female; Genes, p53; Germ Cells; Glycine; Humans; Infant; Li-Fraumeni Syndrome; Male; Middle Aged; Molecular Sequence Data; Mutation; Neoplasms; Pedigree; Sarcoma | 1993 |
Should cancer patients with incurable disease receive parenteral or enteral nutritional support?
Topics: Arginine; Decision Making; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Humans; Neoplasms; Parenteral Nutrition; Prognosis; Quality of Life; Terminal Care | 1998 |
DNA sequence variants of p53: cancer and aging.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Codon; Genes, p53; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Middle Aged; Neoplasms; Odds Ratio; Polymorphism, Genetic; Proline | 1999 |
Single amino acid (arginine) deprivation: rapid and selective death of cultured transformed and malignant cells.
Topics: Animals; Apoptosis; Arginine; Cell Cycle; Cell Line, Transformed; Culture Media; Dipodomys; Flow Cytometry; Humans; Mice; Mink; Neoplasms; Tumor Cells, Cultured | 2000 |
Inactivate the remaining p53 allele or the alternate p73? Preferential selection of the Arg72 polymorphism in cancers with recessive p53 mutants but not transdominant mutants.
Topics: Alleles; Arginine; Genes, Dominant; Humans; Mutation; Neoplasms; Polymorphism, Genetic; Tumor Suppressor Protein p53 | 2001 |
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan | 2001 |
Influence of therapeutic doses of vincristine on the arginine-induced insulin and growth hormone secretions in man.
Topics: Arginine; Blood Glucose; Female; Growth Hormone; Humans; Insulin; Male; Middle Aged; Neoplasms; Vincristine | 1979 |
A cancer-associated, fast, homoarginine-sensitive electrophoretic form of serum alkaline phosphatase.
Topics: Adult; Alkaline Phosphatase; Arginine; Electrophoresis, Cellulose Acetate; Female; Homoarginine; Humans; Isoenzymes; Male; Neoplasms; Remission, Spontaneous | 1978 |
Differential effects of cranial radiation on growth hormone response to arginine and insulin infusion.
Topics: Adolescent; Antineoplastic Agents; Arginine; Brain; Child; Child, Preschool; Female; Growth Hormone; Humans; Hypoglycemia; Infant; Infusions, Parenteral; Insulin; Male; Neoplasms | 1978 |
Urinary excretion of methylarginine in human disease.
Topics: Arginine; Female; Hepatitis; Humans; Liver Diseases; Lupus Erythematosus, Systemic; Male; Multiple Sclerosis; Neoplasms | 1977 |
[Disorders of hemostasis in malignant neoplasms].
Topics: Arginine; Blood Coagulation Disorders; Fibrin; Humans; Neoplasm Metastasis; Neoplasms; Thrombosis | 1977 |
Tumor cytostasis mediated by LPS- or PSK-activated human plastic-adherent peripheral blood mononuclear cells.
Topics: Animals; Arginine; Cell Communication; Cell Cycle; Cells, Cultured; Cytotoxicity, Immunologic; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Neoplasms; Proteoglycans; Putrescine; Tumor Necrosis Factor-alpha | 1992 |
Significance of fibrin formation and dissolution in the pathogenesis and treatment of cancer.
Topics: Arginine; Fibrin; Fibrinolysis; Humans; Models, Biological; Neoplasms; Pyruvaldehyde; Sulfhydryl Compounds; Transglutaminases | 1991 |
[Anticancer therapy with amino acid imbalance].
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine | 1991 |
Cellular models of macrophage tumoricidal effector mechanisms in vitro. Characterization of cytolytic responses to tumor necrosis factor and nitric oxide pathways in vitro.
Topics: Animals; Arginine; Cytotoxicity, Immunologic; Macrophages; Male; Mice; Models, Biological; Mycobacterium bovis; Neoplasms; Nitric Oxide; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1991 |
Recovery of low thymic hormone levels in cancer patients by lysine-arginine combination.
Topics: Adult; Aged; Arginine; Drug Combinations; Female; Humans; Lysine; Male; Middle Aged; Neoplasms; T-Lymphocytes; Thymic Factor, Circulating; Thymus Hormones | 1990 |
Mechanisms of macrophage-mediated tumor cell killing: a comparative analysis of the roles of reactive nitrogen intermediates and tumor necrosis factor.
Topics: Animals; Arginine; Argininosuccinic Acid; Cell Line; Cell Survival; Humans; Immunity, Cellular; Interferon-gamma; Macrophage Activation; Macrophages; Male; Mice; Neoplasms; Nitroarginine; omega-N-Methylarginine; Propionibacterium acnes; Rats; Tumor Necrosis Factor-alpha | 1990 |
Insulin-like growth factors in patients with nonislet cell tumors and hypoglycemia.
Topics: Arginine; Carrier Proteins; Humans; Hypoglycemia; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Neoplasms; Receptors, Cell Surface; Receptors, Somatomedin; Somatomedins | 1986 |
A comparison of the predictive value and diagnostic efficiency of FHAP and CEA as cancer markers.
Topics: Alkaline Phosphatase; Arginine; Carcinoembryonic Antigen; False Positive Reactions; Homoarginine; Humans; Neoplasms | 1986 |
L-arginine independent macrophage tumor cytotoxicity.
Topics: Animals; Arginine; Chromium Radioisotopes; Cytotoxicity, Immunologic; Glucose; Iron Radioisotopes; Leukemia L1210; Macrophage Activation; Macrophages; Mycobacterium bovis; Neoplasms; omega-N-Methylarginine; Tumor Cells, Cultured | 1989 |
H1(0) histones of normal and cancer human cells. Amino acid composition of H1 purified by polyacrylamide gel electrophoresis.
Topics: Amino Acids; Arginine; Carcinoma, Hepatocellular; Cell Line; Histones; Humans; Liver; Liver Neoplasms; Lung; Lung Neoplasms; Lysine; Neoplasms | 1986 |
A hypothesis for the mechanism of tumor killing by NG-hydroxymethyl-L-arginines.
Topics: Animals; Arginine; Cell Division; Formaldehyde; Humans; Neoplasms; Structure-Activity Relationship | 1986 |
Induction of C-type particles in mammalian cancer cells.
Topics: Animals; Arginine; Avian Sarcoma Viruses; Birds; Bromodeoxyuridine; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Genotype; Humans; Leukemia; Leukocytes; Neoplasms; Neoplasms, Experimental; Retroviridae; RNA-Directed DNA Polymerase; RNA, Viral; Sarcoma, Avian; Virus Cultivation; Virus Replication | 1974 |
Arginine-rich low molecular peptides in human neoplastic serum.
Topics: Arginine; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Molecular Weight; Neoplasms; Peptides; Rectal Neoplasms | 1974 |
The arginine content in fibrin clots and fibrinolysis in neoplastic diseases.
Topics: Arginine; Fibrin; Fibrinogen; Fibrinolysis; Humans; Neoplasm Proteins; Neoplasms; Protein Binding | 1973 |
[Effects of oral administration of arginine on the tumor bearing mice (author's transl)].
Topics: Administration, Oral; Animals; Arginine; Body Weight; Catalase; Leukocyte Count; Liver; Male; Mice; Neoplasms; Organ Size; Sarcoma 180; Time Factors | 1973 |
[Radioimmunoassay of arginine vasopressin].
Topics: Arginine; Humans; Methods; Neoplasms; Pituitary Gland, Posterior; Radioimmunoassay; Vasopressins | 1971 |
Arginine content in serum protein and in serum protein fractions in cases of neoplastic disease.
Topics: Arginine; Blood Protein Electrophoresis; Brain Neoplasms; DNA; Esophageal Neoplasms; Female; Humans; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Middle Aged; Neoplasms; Serum Albumin; Serum Globulins; Uterine Neoplasms | 1971 |
The specificity of an increase of albumin fraction arginine in neoplastic diseases.
Topics: Arginine; Humans; Neoplasms; Serum Albumin | 1971 |
Patterns of amino-acid inhibition of alkaline phosphatases as an aid in cancer diagnosis.
Topics: Adenocarcinoma; Alanine; Alkaline Phosphatase; Amino Acids; Animals; Arginine; Colonic Neoplasms; Female; Humans; In Vitro Techniques; Isoenzymes; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms; Phenylalanine; Rats; Valine | 1971 |
TAMe esterase activity in human plasma under normal and pathological conditions.
Topics: Arginine; Cardiovascular Diseases; Colorimetry; Diabetes Mellitus; Disease; Esterases; Glomerulonephritis; Hematologic Diseases; Humans; Hyperthyroidism; Leukemia; Neoplasms; Nephrotic Syndrome; Pancreatic Diseases; Skin Diseases; Stomach Neoplasms | 1968 |
Chromosome aberrations in cultured cells deprived of single essential amino acids.
Topics: Amino Acids; Animals; Arginase; Arginine; Autoradiography; Cell Nucleus; Chromosome Aberrations; Clone Cells; Cricetinae; Culture Media; Culture Techniques; DNA; DNA Replication; Methods; Mitosis; Neoplasms; Proteins; Thymidine; Tritium | 1969 |
[On the differences of in vitro incorporation of C14-arginine and C14-leucine in the mitochondrial protein of various tumor and normal tissues].
Topics: Animals; Arginine; Carbon Isotopes; Cattle; In Vitro Techniques; Leucine; Mice; Mitochondria; Neoplasm Proteins; Neoplasms; Poultry; Rats | 1965 |
Preparation and in vitro-in vivo evaluation of teniposide nanosuspensions.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Compounding; Drug Delivery Systems; Drug Stability; Humans; Microscopy, Electron, Scanning; Nanoparticles; Neoplasms; Particle Size; Povidone; Rats, Wistar; Suspensions; Teniposide; Tumor Burden | 2015 |
Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Butyrates; Chromatin; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Antisense; Drug Interactions; Drug Synergism; Enzyme Inhibitors; Fluorescent Antibody Technique; Gene Expression Profiling; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Mitoxantrone; Neoplasms; Oligonucleotide Array Sequence Analysis; RNA, Small Interfering; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Valproic Acid | 2005 |
Drug activity and therapeutic synergism in cancer treatment.
Topics: Animals; Antineoplastic Agents; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Melanoma; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Rats; Razoxane; Teniposide | 1982 |
New anticancer drug class.
Topics: Child; Etoposide; Humans; Legislation, Drug; Neoplasms; Podophyllotoxin; Teniposide; United States | 1983 |
Toxicity of anticancer drugs used in children.
Topics: Adolescent; Antineoplastic Agents; Asparaginase; Child; Child, Preschool; Cisplatin; Daunorubicin; Doxorubicin; Humans; Methotrexate; Neoplasms; Teniposide | 1980 |
Etoposide (VP16-213) and teniposide (VM26) comparative in vitro activities in human tumors.
Topics: Antineoplastic Agents; Cells, Cultured; Etoposide; Humans; Neoplasms; Neoplasms, Experimental; Podophyllotoxin; Teniposide | 1982 |
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer.
Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
Phase II study of VM-26 in adult malignancies.
Topics: Breast Neoplasms; Colonic Neoplasms; Drug Evaluation; Female; Glioma; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide; Thrombocytopenia | 1980 |
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 11; Combined Modality Therapy; Dactinomycin; DNA-Binding Proteins; Etoposide; Female; Genes; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Whole-Body Irradiation | 1995 |
Enhanced expression of the DNA topoisomerase II gene in response to heat shock stress in human epidermoid cancer KB cells.
Topics: Camptothecin; DNA Topoisomerases, Type II; Etoposide; Gene Expression; Hot Temperature; Humans; Irinotecan; KB Cells; Neoplasms; RNA, Messenger; Teniposide | 1993 |
Overexpression of multidrug resistance protein gene in human cancer cell lines selected for drug resistance to epipodophyllotoxins.
Topics: Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Drug Resistance, Multiple; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Multidrug Resistance-Associated Proteins; Neoplasms; Teniposide; Tumor Cells, Cultured | 1996 |
Overview of early and investigational chemotherapeutic agents in solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Aziridines; Azo Compounds; Camptothecin; Cycloleucine; Etoposide; Floxuridine; Humans; Neoplasms; Nitrogen Mustard Compounds; Picolinic Acids; Platinum; Porfiromycin; Streptonigrin; Teniposide; Thiotepa; Tubercidin | 1976 |
Childhood cancer: the improving prognosis.
Topics: Asparaginase; Child; Cyclophosphamide; Cytosine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Melphalan; Mercaptopurine; Methotrexate; Neoplasms; Nitrogen Mustard Compounds; Osteosarcoma; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Rhabdomyosarcoma; Teniposide; Thioguanine; Vincristine; Wilms Tumor | 1976 |
Comparison of the human pharmacokinetics of VM-26 and VP-16, two antineoplastic epipodophyllotixin glucopyranoside derivatives.
Topics: Body Water; Etoposide; Humans; Metabolic Clearance Rate; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide | 1975 |
Combination chemotherapy based on a model of cell recruitment by partial synchronization.
Topics: Drug Therapy, Combination; Humans; Mitosis; Mitotic Index; Models, Biological; Neoplasm Metastasis; Neoplasms; Podophyllotoxin; Remission, Spontaneous; Teniposide; Time Factors; Vincristine | 1975 |
Anoxia-inducible endonuclease activity as a potential basis of the genomic instability of cancer cells.
Topics: Animals; Cell Hypoxia; Cell Survival; DNA Probes; DNA, Neoplasm; Endonucleases; Enzyme Induction; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Liver Neoplasms, Experimental; Molecular Weight; Neoplasms; Plasmids; Rats; Teniposide; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1992 |
Current perspectives on teniposide (VM-26): an international conference. Proceedings. London, September 2, 1989.
Topics: Animals; Humans; Neoplasms; Teniposide | 1992 |
A phase I study of daily oral teniposide for 20 days.
Topics: Administration, Oral; Aged; Bone Marrow; Clinical Trials, Phase I as Topic; Drug Administration Schedule; Female; Humans; Leukopenia; Male; Middle Aged; Nausea; Neoplasms; Teniposide; Thrombocytopenia; Vomiting | 1992 |
Aberrant DNA topoisomerase II activity, radioresistance and inherited susceptibility to cancer.
Topics: Amsacrine; Ataxia Telangiectasia; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cytarabine; Cytoplasm; DNA Repair; DNA Topoisomerases, Type II; DNA, Circular; DNA, Superhelical; Female; Fibroblasts; Gene Expression; Genetic Predisposition to Disease; Humans; Male; Neoplasms; Oncogenes; Radiation Tolerance; Teniposide; Topoisomerase II Inhibitors | 1991 |
Human DNA topoisomerase II: evaluation of enzyme activity in normal and neoplastic tissues.
Topics: Adolescent; Adult; Aged; Cell Cycle; DNA Topoisomerases, Type II; DNA, Bacterial; Escherichia coli; Female; Flow Cytometry; Genes, Immunoglobulin; Hot Temperature; Humans; Male; Middle Aged; Neoplasms; Organ Specificity; Placenta; Spleen; Teniposide | 1990 |
[Phase I trial and pharmacokinetics of VM 26 combined with cisplatin administered by the intraperitoneal route without mixing time].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Evaluation; Humans; Injections, Intraperitoneal; Middle Aged; Neoplasms; Podophyllotoxin; Teniposide | 1989 |
Treatment strategies in relation to drug action.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide | 1987 |
High-dose teniposide for refractory malignancies: a phase I study.
Topics: Adult; Aged; Alopecia; Drug Evaluation; Female; Hematologic Diseases; Humans; Male; Middle Aged; Nausea; Neoplasms; Podophyllotoxin; Skin Diseases; Teniposide | 1986 |