arginine has been researched along with Leucocythaemia in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (45.76) | 18.7374 |
| 1990's | 18 (30.51) | 18.2507 |
| 2000's | 8 (13.56) | 29.6817 |
| 2010's | 5 (8.47) | 24.3611 |
| 2020's | 1 (1.69) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J; Dong, W; He, Y; Liu, Y; Luo, J | 1 |
| Chen, K; Chen, S; Chen, Z; Ding, H; Jiang, H; Jin, J; Lian, F; Liu, YC; Luo, C; Wang, C; Xie, Y; Yao, Z; Ye, F; Zhang, C; Zhang, H; Zhang, N; Zhang, Y | 1 |
| Gusachenko, I; Lymanets, T; Maslova, G; Skrypnyk, I | 1 |
| Darzy, KH; Shalet, SM; Thorner, MO | 1 |
| Brown, GC; Brown, RD; Burke, GA | 1 |
| Cui, J; Du, Z; He, K; Li, A; Li, D; Li, L; Li, W; Li, Y; Liang, T; Liu, N; Wang, G; Wang, J; Wang, N; Yang, G | 1 |
| Bianchi, N; Brognara, E; Corradini, R; Fabbri, E; Gambari, R; Manicardi, A; Marchelli, R; Sforza, S; Tedeschi, T | 1 |
| Cvetkovic, G; Evans, CH; Modiano, JF; O'Brien, TD; Rütgen, BC; Scott, MC; Tepic, S; Wells, JW | 1 |
| Fujino, T; Ishida, S; Murayama, N; Nagano, M; Nakamura, T; Niimi, S; Nishimura, T; Ozawa, S; Saito, Y; Sawada, J | 1 |
| Foss, FM; Gorgun, G; Shao, RH; Tian, X; Urbano, AG | 1 |
| BUTLER, JA; LAURENCE, DJ | 1 |
| Darzy, KH; Pezzoli, SS; Shalet, SM; Thorner, MO | 1 |
| Dugas, M; Hiddemann, W; Kaza, SK; Kern, R; Malamoussi, T; Mellert, G; Reindl, C; Schnittger, S; Spiekermann, K; Vempati, S | 1 |
| Holcenberg, JS | 1 |
| Christopherson, RI; Duggleby, RG; Hindmarsh, EJ; Phillips, L; Szabados, E | 1 |
| Balabanova, H; Becker, Y; Friedmann, A; Kotler, M; Weinberg, E | 1 |
| Cohen, JS; Egan, W; Shindo, H | 1 |
| Kass, L | 1 |
| Gabius, HJ; Zeng, FY | 1 |
| Becker, Y; Haspel, O; Kotler, M; Olshevsky, U; Weinberg, E | 1 |
| Balabanova, G; Becker, Y; Kotler, M; Weinberg, E | 1 |
| Hersh, EM | 1 |
| Stacher, A; Stöckl, W; Weiser, M; Zacherl, MK | 1 |
| Billardon, C; Breitburd, F; Delarue, JC; Le Borgne de Kaouel, C; Picard, JY | 1 |
| Abe, K; Kumagai, N; Mouri, T; Seki, T; Yoshinaga, K | 1 |
| Seiter, K | 1 |
| Gahrton, G | 1 |
| Płuzańska, A; Robak, T | 1 |
| Alonso, MT; Leyland-Jones, B; Marsoni, S; O'Dwyer, PJ | 1 |
| Crom, WR; Dow, L; Evans, WE; Look, AT; Rivera, G; Sinkule, JA | 1 |
| Gershanovich, ML; Kondrat'ev, VB; Kondrat'eva, NA; Lebedev, VN; Vygovskaia, IaI | 1 |
| Catapano, CV; Fernandes, DJ; Qiu, J | 1 |
| Beck, WT; Chen, M | 2 |
| Felix, CA; Hosler, MR; Lange, BJ; Masterson, M; Wilson, AE; Winick, NJ | 1 |
| Muggia, FM | 1 |
| Evans, WE; McLeod, HL | 1 |
| Chorus, AM; Hagenbeek, A; Noyon, R; Pinedo, HM; Somers, R; van den Belt-Dusebout, AW; van Kerkhoff, EH; van Leeuwen, FE | 1 |
| Bower, M; Chaplin, T; Das, S; Gibbons, B; Kearney, L; Lister, TA; Riley, JH; Young, BD | 1 |
| Studzinski, GP; Tepper, CG | 1 |
| Broeker, PL; Pomykala, H; Rowley, JD; Super, HG; Tanabe, S; Thirman, MJ; Yonebayashi, Y; Zeleznik-Le, N | 1 |
| Beck, WT; Khélifa, T; Kusumoto, H; Mo, YY; Rodgers, Q; Wang, Q; Wolverton, JS | 1 |
| Beck, WT; Bhat, UG; Kim, R; Kusumoto, H; Lu, T; Morgan, SE; Wang, PC | 1 |
| Bunn, PA; Ihde, DC; Radice, PA | 1 |
| Henney, JE; Muggia, FM; Rozencweig, M; Von Hoff, DD | 1 |
| Bleyer, WA; Chard, RL; Hammond, D; Krivit, W | 1 |
| Crooke, ST; Gutierrez, ML | 1 |
| Donaldson, MH; Rosenstock, JG | 1 |
| Hong, JH; Kamada, N; Kobayashi, M; Komazawa, Y; Kuramoto, A; Kusunoki, Y; Mizuno, T; Mizutani, A; Okada, K | 1 |
| Lorico, A; Rappa, G; Sartorelli, AC | 1 |
| Sonneveld, P | 1 |
| Busch, FW; Ehninger, G; Hiddemann, W; Jaschonek, K; Proksch, B; Schleyer, E; Schmidt, H; Schuler, U; Wanner, T | 1 |
| Beck, WT; Danks, MK; Fernandes, DJ | 1 |
| McVie, G; Muggia, FM | 1 |
| Beck, WT; Cirtain, MC; Danks, MK; Felsted, RL; Safa, AR; Suttle, DP; Trent, JM; Wolverton, JS | 1 |
| White, JC; Wright, SE | 1 |
| Fortner, CL; King, SA; Leyland-Jones, B; O'Dwyer, PJ | 1 |
| Abromowitch, M; Evans, WE; Hayes, FA; Rivera, GK; Rodman, JH; Sinkule, JA | 1 |
| Hines, LH; Rathmell, JP; White, JC | 1 |
10 review(s) available for arginine and Leucocythaemia
| Article | Year |
|---|---|
Immunosuppression by L-asparaginase and related enzymes.
Topics: Animals; Arginine; Asparaginase; Glutaminase; Graft Rejection; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Immunosuppressive Agents; In Vitro Techniques; L-Serine Dehydratase; Leukemia; Lymphocyte Activation; Lymphoid Tissue; Lymphoma; Mice; Rabbits; Transplantation, Homologous | 1971 |
Toxicity of the topoisomerase II inhibitors.
Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases | 2005 |
Treatment of acute leukemia--advances in chemotherapy, immunotherapy, and bone marrow transplantation.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aminoacridines; Amsacrine; Anthraquinones; Antibodies, Monoclonal; Azacitidine; Bone Marrow Transplantation; Child; Child, Preschool; Drug Administration Schedule; Etoposide; Humans; Ifosfamide; Immunotherapy; Infant; Interferons; Leukemia; Leukemia, Lymphoid; Liposomes; Middle Aged; Mitoxantrone; Naphthacenes; Prognosis; Teniposide; Transplantation, Homologous; Transplantation, Isogeneic; Vinblastine; Vindesine | 1983 |
Teniposide: a review of 12 years of experience.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide | 1984 |
Teniposide: overview of its therapeutic potential in adult cancers.
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Clinical Trials as Topic; Clinical Trials, Phase I as Topic; Etoposide; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms; Sarcoma, Kaposi; Teniposide | 1994 |
Clinical pharmacokinetics and pharmacodynamics of epipodophyllotoxins.
Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance; Etoposide; Humans; Leukemia; Neoplasms; Neoplasms, Second Primary; Teniposide; Topoisomerase II Inhibitors | 1993 |
The isolation of a yeast artificial chromosome which spans the chromosome 11q23 region involved in a number of translocations in acute leukaemias.
Topics: Acute Disease; Adult; Aged; Child; Chromosome Mapping; Chromosomes, Human, Pair 11; Female; Gene Library; Genes, Fungal; Humans; In Situ Hybridization; Infant; Leukemia; Male; Polymerase Chain Reaction; Teniposide; Translocation, Genetic; Yeasts | 1993 |
VM 26 and VP 16-213: a comparative analysis.
Topics: Animals; Brain Neoplasms; Drug Evaluation; Etoposide; Humans; Kinetics; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms, Experimental; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1977 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Teniposide in lymphomas and leukemias.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Child; Humans; Leukemia; Lymphoma; Teniposide | 1992 |
7 trial(s) available for arginine and Leucocythaemia
| Article | Year |
|---|---|
L-arginine is an effective medication for prevention of endothelial dysfunction, a predictor of anthracycline cardiotoxicity in patients with acute leukemia.
Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Agents; Antioxidants; Arginine; Cardiotoxicity; Endothelium, Vascular; Female; Heart; Humans; Leukemia; Male; Middle Aged; Young Adult | 2017 |
[New antineoplastic drugs of the podophyllotoxin derivative group].
Topics: Adult; Child; Clinical Trials as Topic; Etoposide; Female; Humans; Leukemia; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms | 1983 |
Teniposide: a review of 12 years of experience.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Cycle; Cell Line; Child; Clinical Trials as Topic; Colonic Neoplasms; DNA, Neoplasm; Drug Evaluation, Preclinical; Drug Resistance; Humans; Leukemia; Lymphoma; Mice; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Podophyllotoxin; Teniposide | 1984 |
Therapeutic trials with VP-16-213 and VM-26: active agents in small cell lung cancer, non-Hodgkin's lymphomas, and other malignancies.
Topics: Alopecia; Carcinoma, Small Cell; Clinical Trials as Topic; Drug Evaluation; Etoposide; Humans; Leukemia; Leukopenia; Lung Neoplasms; Lymphoma; Podophyllotoxin; Teniposide | 1979 |
Phase II study of VM-26 in acute leukemia, neuroblastoma, and other refractory childhood malignancies: a report from the Children's Cancer Study Group.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow; Child; Clinical Trials as Topic; Drug Evaluation; Humans; Leukemia; Leukemia, Lymphoid; Neoplasms; Neuroblastoma; Podophyllotoxin; Remission, Spontaneous; Teniposide | 1979 |
Pediatric cancer chemotherapy: an updated review. I. Cis-Diammine--dichloroplatinum II (cisplatin), VM-26 (teniposide), VP-16 (etoposide), mitomycin C.
Topics: Child; Cisplatin; Clinical Trials as Topic; Drug Administration Schedule; Etoposide; Humans; Leukemia; Mitomycins; Neoplasms; Podophyllotoxin; Teniposide | 1979 |
Phase I-II trial of VM-26 (NSC-122819) in the treatment of children with late-stage leukemia.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Drug Evaluation; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Podophyllotoxin; Teniposide | 1976 |
44 other study(ies) available for arginine and Leucocythaemia
| Article | Year |
|---|---|
A Novel Form of Arginine-Chitosan as Nanoparticles Efficient for siRNA Delivery into Mouse Leukemia Cells.
Topics: Animals; Arginine; Chitosan; Leukemia; Mice; Nanoparticles; Particle Size; RNA, Small Interfering; Spectroscopy, Fourier Transform Infrared | 2023 |
Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.
Topics: Apoptosis; Arginine; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Diamines; Enzyme Inhibitors; Humans; Leukemia; Protein-Arginine N-Methyltransferases; Repressor Proteins | 2017 |
Cranially irradiated adult cancer survivors may have normal spontaneous GH secretion in the presence of discordant peak GH responses to stimulation tests (compensated GH deficiency).
Topics: Adolescent; Adult; Arginine; Brain Neoplasms; Case-Control Studies; Female; Follow-Up Studies; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Insulin; Insulin-Like Growth Factor I; Leukemia; Lymphoma; Male; Middle Aged; Radiotherapy; Young Adult | 2009 |
Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine.
Topics: Acetylcysteine; Antioxidants; Arginase; Arginine; Ascorbic Acid; Azoles; Catalase; Cell Death; Cell Line, Tumor; Cell Proliferation; Humans; Hydrogen Peroxide; Isoindoles; Leukemia; Organoselenium Compounds | 2009 |
Identification of complement C3f-desArg and its derivative for acute leukemia diagnosis and minimal residual disease assessment.
Topics: Acute Disease; Adolescent; Adult; Aged; Amino Acid Sequence; Arginine; Biomarkers, Tumor; Complement C3b; Female; Humans; Leukemia; Male; Middle Aged; Molecular Sequence Data; Neoplasm, Residual; Proteomics; Young Adult | 2010 |
Cellular uptakes, biostabilities and anti-miR-210 activities of chiral arginine-PNAs in leukaemic K562 cells.
Topics: Arginine; Base Sequence; Biological Transport; Cell Differentiation; DNA; Erythroid Cells; Humans; K562 Cells; Leukemia; MicroRNAs; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Peptide Nucleic Acids; RNA; Stereoisomerism; Transition Temperature | 2012 |
Arginase treatment prevents the recovery of canine lymphoma and osteosarcoma cells resistant to the toxic effects of prolonged arginine deprivation.
Topics: Adult Stem Cells; Animals; Antineoplastic Agents; Apoptosis; Arginase; Arginine; Bone Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Culture Media; Dogs; Leukemia; Lymphoma; Osteosarcoma | 2013 |
Substitution of arginine for cysteine 643 of the glucocorticoid receptor reduces its steroid-binding affinity and transcriptional activity.
Topics: Amino Acid Substitution; Arginine; Cysteine; Dexamethasone; DNA Mutational Analysis; Humans; Leukemia; Protein Binding; Receptors, Glucocorticoid; Transcription, Genetic; Tumor Cells, Cultured | 2002 |
Arginine butyrate increases the cytotoxicity of DAB(389)IL-2 in leukemia and lymphoma cells by upregulation of IL-2Rbeta gene.
Topics: Antineoplastic Combined Chemotherapy Protocols; Arginine; Butyrates; Cell Survival; Cyclic AMP; Diphtheria Toxin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Interleukin-2; Interleukin-2 Receptor beta Subunit; Leukemia; Lymphoma; Receptors, Interleukin; Receptors, Interleukin-2; Recombinant Fusion Proteins; Response Elements; Second Messenger Systems; Up-Regulation | 2002 |
METABOLISM OF HISTONES IN MALIGNANT TISSUES AND LIVER OF THE RAT AND MOUSE.
Topics: Amino Acids; Animals; Arginine; Carcinoma; Carcinoma, Krebs 2; Chemistry Techniques, Analytical; DNA; Glycine; Growth; Histones; Leukemia; Leukemia, Experimental; Liver; Lysine; Metabolism; Mice; Neoplasm Proteins; Proteins; Rats; Research | 1965 |
Cranial irradiation and growth hormone neurosecretory dysfunction: a critical appraisal.
Topics: Adolescent; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Adult; Arginine; Brain Neoplasms; Cluster Analysis; Fasting; Female; Glucose Tolerance Test; Human Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Leukemia; Male; Middle Aged; Pituitary Diseases; Radiotherapy; Sex Characteristics; Survivors | 2007 |
Arginine 595 is duplicated in patients with acute leukemias carrying internal tandem duplications of FLT3 and modulates its transforming potential.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Cell Transformation, Neoplastic; Female; fms-Like Tyrosine Kinase 3; Gene Duplication; Humans; Leukemia; Male; Middle Aged; Mutagenesis; Sequence Deletion | 2007 |
Enzyme therapy of cancer, future studies.
Topics: Adolescent; Amidohydrolases; Animals; Antineoplastic Agents; Arginine; Asparaginase; Asparagine; Child; Child, Preschool; Drug Evaluation; Drug Evaluation, Preclinical; Enzyme Therapy; Enzymes; Female; Glutaminase; Glutamine; Humans; Kinetics; Leukemia; Male; Mice | 1981 |
5-Aminoimidazole-4-carboxamide ribotide transformylase-IMP cyclohydrolase from human CCRF-CEM leukemia cells: purification, pH dependence, and inhibitors.
Topics: Acyltransferases; Arginine; Binding Sites; Cysteine; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Hydroxymethyl and Formyl Transferases; Kinetics; Leukemia; Nucleotide Deaminases; Nucleotides; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphorylation; Purines; Spectrophotometry; Tumor Cells, Cultured | 1994 |
Oncornavirus-like particles released from arginine-deprived human lymphoblastoid cell lines.
Topics: Arginine; Burkitt Lymphoma; Cell Line; DNA, Viral; Kinetics; Leukemia; Nucleic Acid Hybridization; Retroviridae; RNA-Directed DNA Polymerase | 1975 |
Studies of individual carboxyl groups in proteins by carbon 13 nuclear magnetic resonance spectroscopy.
Topics: Acetylglucosamine; Amino Acids, Dicarboxylic; Animals; Arginine; Cattle; Chickens; Egg White; Humans; Kinetics; Leukemia; Magnetic Resonance Spectroscopy; Muramidase; Ribonucleases | 1978 |
Histone abnormalities in adult acute leukemias.
Topics: Adult; Arginine; Electrophoresis, Disc; Esterases; Hematopoietic Stem Cells; Histones; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lysine; Monocytes | 1975 |
Carbohydrate-binding specificity of calcyclin and its expression in human tissues and leukemic cells.
Topics: Acetylglucosamine; alpha-Fetoproteins; Animals; Arginine; Biotin; Calcium; Calcium-Binding Proteins; Carbohydrate Metabolism; Carbohydrates; Cattle; Cell Cycle Proteins; Cell Nucleus; Cytoplasm; G(M1) Ganglioside; Glycoproteins; Humans; Lactose; Leukemia; Lysine; Mannose; Mucins; Myocardium; S100 Calcium Binding Protein A6; S100 Proteins; Submandibular Gland; Tumor Cells, Cultured | 1991 |
Particles released from arginine deprived human leukaemic cells.
Topics: Arginine; Cells, Cultured; Centrifugation, Density Gradient; Culture Media; DNA, Viral; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Microscopy, Electron; Oncogenic Viruses; Ribonucleases; RNA-Directed DNA Polymerase; RNA, Ribosomal; Templates, Genetic; Tritium; Uridine; Virus Cultivation | 1973 |
Induction of C-type particles in mammalian cancer cells.
Topics: Animals; Arginine; Avian Sarcoma Viruses; Birds; Bromodeoxyuridine; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Genotype; Humans; Leukemia; Leukocytes; Neoplasms; Neoplasms, Experimental; Retroviridae; RNA-Directed DNA Polymerase; RNA, Viral; Sarcoma, Avian; Virus Cultivation; Virus Replication | 1974 |
[Behavior of free amino acids in the blood of leukemia patients following amino acid infusion].
Topics: Adult; Aged; Amino Acids; Arginine; Female; Glycine; Histidine; Humans; Infusions, Parenteral; Isoleucine; Leucine; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Lysine; Male; Methionine; Phenylalanine; Threonine; Tryptophan; Valine | 1968 |
[Biochemical study of continuous human blood cell lines. Comparative study with fresh cells].
Topics: Amino Acids; Arginine; Cell Line; Chromatography; Culture Media; Culture Techniques; Electrophoresis; Humans; Leukemia; Lymphocytes | 1971 |
TAMe esterase activity in human plasma under normal and pathological conditions.
Topics: Arginine; Cardiovascular Diseases; Colorimetry; Diabetes Mellitus; Disease; Esterases; Glomerulonephritis; Hematologic Diseases; Humans; Hyperthyroidism; Leukemia; Neoplasms; Nephrotic Syndrome; Pancreatic Diseases; Skin Diseases; Stomach Neoplasms | 1968 |
Pharmacokinetics of Teniposide (VM26) and etoposide (VP16-213) in children with cancer.
Topics: Biotransformation; Child; Chromatography, High Pressure Liquid; Etoposide; Humans; Kinetics; Leukemia; Models, Biological; Neoplasms; Podophyllotoxin; Teniposide | 1982 |
[Use of VM 26 (epipodophyllotoxin) in treating acute leukemias and lymphomas in the adult].
Topics: Acute Disease; Adult; Drug Evaluation; Hodgkin Disease; Humans; Leukemia; Lymphoma; Podophyllotoxin; Teniposide; Time Factors | 1981 |
DNA topoisomerase II isozymes involved in anticancer drug action and resistance.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Cell Nucleus; DNA Topoisomerases, Type II; DNA, Neoplasm; Drug Resistance, Neoplasm; Humans; Isoenzymes; Leukemia; Nuclear Matrix; Sodium Chloride; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1995 |
DNA topoisomerase II expression, stability, and phosphorylation in two VM-26-resistant human leukemic CEM sublines.
Topics: Amino Acids; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Multiple; Enzyme Stability; Gene Expression; Humans; Isoenzymes; Leukemia; Phosphorylation; Poly-ADP-Ribose Binding Proteins; Teniposide; Tumor Cells, Cultured | 1995 |
ALL-1 gene rearrangements in DNA topoisomerase II inhibitor-related leukemia in children.
Topics: Acute Disease; Adolescent; Bone Marrow Transplantation; Child; Child, Preschool; Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, Pair 11; Combined Modality Therapy; Dactinomycin; DNA-Binding Proteins; Etoposide; Female; Genes; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Myelodysplastic Syndromes; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogenes; Radiotherapy; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Whole-Body Irradiation | 1995 |
Leukemia risk following Hodgkin's disease: relation to cumulative dose of alkylating agents, treatment with teniposide combinations, number of episodes of chemotherapy, and bone marrow damage.
Topics: Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Case-Control Studies; Female; Hodgkin Disease; Humans; Leukemia; Lomustine; Male; Mechlorethamine; Middle Aged; Neoplasms, Second Primary; Risk Factors; Teniposide | 1994 |
Teniposide-resistant CEM cells, which express mutant DNA topoisomerase II alpha, when treated with non-complex-stabilizing inhibitors of the enzyme, display no cross-resistance and reveal aberrant functions of the mutant enzyme.
Topics: Cell Cycle; Chromosomes; DNA; DNA Topoisomerases, Type II; Drug Resistance; Humans; Leukemia; Mutation; Proteins; Teniposide; Thiobarbiturates; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1993 |
Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death.
Topics: Apoptosis; DNA Damage; DNA, Mitochondrial; DNA, Neoplasm; Doxorubicin; Drug Resistance; Humans; Leukemia; Necrosis; Teniposide; Tumor Cells, Cultured | 1993 |
Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents, Phytogenic; Base Sequence; Binding Sites; Centromere; Child; Child, Preschool; Chromatin; Chromosomes, Human, Pair 11; Consensus Sequence; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Neoplasm; Etoposide; Female; Histone-Lysine N-Methyltransferase; Humans; Infant; Leukemia; Male; Middle Aged; Molecular Sequence Data; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Proto-Oncogenes; Telomere; Teniposide; Topoisomerase II Inhibitors; Transcription Factors; Translocation, Genetic; Tumor Cells, Cultured | 1996 |
Novel mechanisms of resistance to inhibitors of DNA topoisomerases.
Topics: Antineoplastic Agents; Apoptosis; Cell Nucleus; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Enzyme Inhibitors; G2 Phase; Genes, jun; Humans; Leukemia; RNA, Messenger; Signal Transduction; Teniposide; Thiobarbiturates; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1997 |
Differences in mutant p53 protein stability and functional activity in teniposide-sensitive and -resistant human leukemic CEM cells.
Topics: Antineoplastic Agents; bcl-2-Associated X Protein; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA, Neoplasm; Drug Resistance, Neoplasm; GADD45 Proteins; Humans; Intracellular Signaling Peptides and Proteins; Leukemia; Nuclear Proteins; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Protein Binding; Protein Biosynthesis; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-mdm2; Teniposide; Transcriptional Activation; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Isolation and characterization of VP-16 resistant human leukemia cell line.
Topics: DNA Replication; Dose-Response Relationship, Drug; Herpes Simplex Virus Protein Vmw65; Humans; Leukemia; Organophosphorus Compounds; Teniposide; Time Factors; Tumor Cells, Cultured | 1990 |
Potentiation by novobiocin of the cytotoxic activity of etoposide (VP-16) and teniposide (VM-26).
Topics: Adenocarcinoma; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; DNA; DNA Topoisomerases, Type II; Drug Synergism; Etoposide; Humans; Leukemia; Lung Neoplasms; Novobiocin; RNA; Teniposide; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1992 |
Intracellular cytosine arabinoside accumulation and cytosine arabinoside triphosphate formation in leukemic blast cells is inhibited by etoposide and teniposide.
Topics: Acute Disease; Adult; Aged; Amsacrine; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Interactions; Etoposide; Humans; Leukemia; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Teniposide; Tumor Cells, Cultured | 1992 |
Decreased nuclear matrix DNA topoisomerase II in human leukemia cells resistant to VM-26 and m-AMSA.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Nucleus; Crithidia; DNA; DNA Topoisomerases, Type II; Drug Resistance; Humans; Leukemia; Podophyllotoxin; Teniposide; Tumor Cells, Cultured | 1990 |
Treatment strategies in relation to drug action.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; DNA Topoisomerases, Type II; Etoposide; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma, Non-Hodgkin; Neoplasms; Podophyllotoxin; Teniposide | 1987 |
Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Chloroquine; Chromosome Banding; Chromosomes, Human, Pair 13; Colchicine; Dactinomycin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia; Membrane Glycoproteins; Molecular Weight; Podophyllotoxin; Teniposide; Tumor Cells, Cultured; Verapamil; Vinblastine; Vinca Alkaloids | 1987 |
Membrane ordering effects of the anticancer agent VM-26.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Cholesterol; Cyclic N-Oxides; Dimyristoylphosphatidylcholine; Electron Spin Resonance Spectroscopy; Etoposide; Humans; Leukemia; Lipid Bilayers; Liposomes; Male; Membrane Lipids; Mice; Podophyllotoxin; Spin Labels; Teniposide | 1986 |
Hypersensitivity reactions to teniposide (VM-26): an analysis.
Topics: Adolescent; Adult; Aged; Bibliographies as Topic; Blood Pressure; Brain Neoplasms; Child; Child, Preschool; Data Collection; Drug Evaluation; Drug Hypersensitivity; Edema; Humans; Hypersensitivity, Immediate; Infant; Leukemia; Male; Middle Aged; Neuroblastoma; Podophyllotoxin; Surveys and Questionnaires; Teniposide; Urticaria | 1986 |
Clinical pharmacodynamics of continuous infusion teniposide: systemic exposure as a determinant of response in a phase I trial.
Topics: Child; Drug Administration Schedule; Drug Evaluation; Humans; Infusions, Parenteral; Kinetics; Leukemia; Lymphoma; Neuroblastoma; Podophyllotoxin; Teniposide | 1987 |
Inhibition of 1-beta-D-arabinofuranosylcytosine transport and net accumulation by teniposide and etoposide in Ehrlich ascites cells and human leukemic blasts.
Topics: Animals; Binding Sites; Biological Transport; Carcinoma, Ehrlich Tumor; Cells, Cultured; Cytarabine; Etoposide; Humans; Leukemia; Male; Mice; Mice, Inbred Strains; Podophyllotoxin; Teniposide; Thioinosine; Tritium | 1985 |