arginine has been researched along with Disease Models, Animal in 1131 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (2.65) | 18.7374 |
| 1990's | 203 (17.95) | 18.2507 |
| 2000's | 371 (32.80) | 29.6817 |
| 2010's | 449 (39.70) | 24.3611 |
| 2020's | 78 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Abel, ED; Chen, B; Ciampa, G; Hall, DD; Peng, T; Shi, Q; Song, LS; Wang, J; Zheng, D | 1 |
| Abbaszadeh, F; Fakhri, S; Farzaei, MH; Mohammadi, S; Mohammadi-Farani, A | 1 |
| Bulak, K; Fichna, J; Talar, M; Tarasiuk, A | 1 |
| Boermeester, MA; de Boer, RJ; Dekker, E; Hakvoort, TBM; Hawinkels, LJAC; Heijmans, J; Koelink, PJ; Koster, J; Meijer, BJ; Meisner, S; Muncan, V; Smit, WL; Struijs, EA; van den Brink, GR; van der Meer, JHM; van Roest, M; Vermeulen, JLM | 1 |
| Adams, V; Bahls, M; Baskal, S; Besler, C; Büttner, P; Knauth, S; Lurz, P; Schwedhelm, E; Thiele, H; Tsikas, D; Werner, S | 1 |
| Ghildyal, R; Hu, M; Jans, DA; Li, HM; Mills, J; Starrs, LM; Teng, MN; Tran, KC | 1 |
| Fazli-Tabaei, S; Khakpai, F; Zarrindast, MR | 1 |
| Hirokawa, F; Jin, D; Komeda, K; Kuramoto, T; Takai, S; Taniguchi, K; Uchiyama, K | 1 |
| Cimarosti, H; de Lima, TCM; Linartevichi, VF; Soares, ES; Vanz, F | 1 |
| Bendavid, C; Bordeau, V; Cattoir, V; Cogné, M; Coirier, V; Creusat, F; Daniel, Y; Delaloy, C; Dessauge, E; Dessauge, F; Fromenty, B; Gacouin, A; Gauthier, J; Grégoire, M; Lamaison, C; Le Naoures, C; Le Tulzo, Y; Lesouhaitier, M; Michelet, C; Moreau, C; Petitjean, K; Piau, C; Reizine, F; Roussel, M; Tadié, JM; Tarte, K; Thibault, R; Uhel, F; Zmijewski, J | 1 |
| Cadena, SMSC; Corrêa-Ferreira, ML; Dias, AIBDS; Fachin, CG; Ioshii, SO; Moreira, GA | 1 |
| Dawra, RK; Dudeja, V; George, J; Giri, B; Iyer, S; Jain, T; Palathingal Bava, E; Sahay, P; Saluja, AK; Sharma, P; Tarique, M; Vaish, U | 1 |
| Chen, X; Chen, Y; Huang, Y; Wang, J; Yang, H; Yao, L; Yu, X; Zhu, Y | 1 |
| Hashimoto, S; Ishii, A; Kamano, N; Matsuba, Y; Mihira, N; Muramatsu, SI; Saido, TC; Saito, T; Yokosuka, M | 1 |
| Chen, J; Hu, C; Huang, L; Liang, G; Liu, X; Luo, W; Mutsinze, RN; Wang, X; Wang, Y; Zhang, Y; Zuo, W | 1 |
| Andersson, DC; Carlström, M; Gastaldello, S; Lanner, JT; Lund, LH; Pironti, G; Rassier, DE; Westerblad, H; Yamada, T | 1 |
| Chen, J; Chen, Y; Liang, J; Luo, X; Pan, S; Pan, Z; Wang, Q; Wu, Z; Xie, X; Yang, C; Zhang, M; Zhou, L | 1 |
| Das, A; Ojha, DK; Reddy, KS; Sahu, W; Suar, M | 1 |
| Ahmed, F; Coonrod, SA; Demeter, EA; Grenier, JK; Marks, BA; Mittal, C; Mukai, C; Nelissen, S; Sams, KL; Tate, AE | 1 |
| Deane, AR; Jing, Y; Liu, P; Shoorangiz, R; Ward, RD | 1 |
| Aghdassi, AA; Bornscheuer, UT; Doller, J; Gischke, M; Glaubitz, J; Lalk, M; Lerch, MM; Sendler, M; Tran, QT; Tran, VH; Weiss, FU; Wiese, ML; Zierke, L | 1 |
| Abbas, A; Baldassano, RN; Bushman, FD; Bustin, KA; Di, C; Dunny, GM; Erlichman, J; Evans, DR; Furth, EE; Gaddy, JA; Green, J; Hart, JL; Jenior, ML; Keenan, O; Kelly, BJ; Laut, C; Matthews, ML; Nicholson, MR; Papin, JA; Prentice, BM; Rangel, PC; Silverman, MA; Skaar, EP; Smith, AB; Specker, J; Van Tyne, D; Zackular, JP | 1 |
| Chiba, Y; Fu, Y; Fukumoto, S; Funada, K; Iwamoto, T; Kawahara, J; Miyazaki, K; Mizuta, K; Takahashi, I; Tian, T; Yoshizaki, K; Yuta, T | 1 |
| Chen, F; Feng, Y; Hu, X; Li, D; Ma, C | 1 |
| Kamali, GH; Ozdenkaya, Y; Tazeoglu, A; Tazeoglu, D | 1 |
| Dogru, YZ; Erat, M; Nacar, T | 1 |
| Brown, LAS; George, RP; Harris, F; Jo, H; Kelleman, M; Morris, CR; Reyes, LZ; Winterberg, PD | 1 |
| Aoki, T; Kodama, T; Kurashige, S; Matsutani, N; Otagiri, Y; Togashi, Y | 1 |
| Bomalaski, JS; Deorukhkar, AA; Krishnan, S; Li, X; Singh, PK; Tailor, R; Venkatesulu, BP | 1 |
| Aderibigbe, AO; Ajayi, AM; Ben-Azu, B; Iwalewa, EO; Umukoro, S | 1 |
| Allegri, G; Burke, KE; Cederbaum, SD; Häberle, J; Lipshutz, GS; Liu, XB; Martini, PGV; Truong, B; Zhu, X | 1 |
| Chalmers, S; Hargrave, KE; Millington, O; Roberts, CW; Westrop, GD; Woods, S | 1 |
| Bossaller, L; Bröker, BM; De Freitas Chama, LL; Glaubitz, J; Golchert, J; Homuth, G; Lerch, MM; Mahajan, UM; Mayerle, J; Mishra, N; Sendler, M; van den Brandt, C; Völker, U; Weiss, FU; Wilden, A | 1 |
| Chen, YC; Hsiao, CC; Hsu, MH; Huang, LT; Sheen, JM; Wang, SC | 1 |
| Cao, P; Gao, X; Han, D; Huang, N; Kou, J; Luan, J; Ma, N; Murtaza, G; Qiao, Y; Shi, S; Sun, Y; Tao, Y; Wang, L; Wang, X; Wu, X | 1 |
| Hu, W; Liu, T; Ma, Q; Wang, W; Zhang, J | 1 |
| Catalin, B; Dumbrava, D; Gresita, A; Hermann, DM; Olaru, DG; Popa-Wagner, A; Surugiu, R | 1 |
| Bi, JB; Liu, WM; Lv, Y; Ren, YF; Wang, MZ; Wei, SS; Wu, RQ; Wu, Z; Zhang, J; Zhang, L | 1 |
| Bollenbach, A; Jörns, A; Lenzen, S; Tsikas, D | 1 |
| Cheng, L; Duan, XM; Luo, ZL; Ren, JD; Sun, HY; Wu, XB | 1 |
| Alemagno, M; Asosingh, K; Bennett, C; Erzurum, S; Frimel, M; Kessler, S; Lauruschkat, CD; Meyers, DA; Wanner, N; Weiss, K; Xu, W | 1 |
| Carrera Silva, EA; Cerbán, FM; Gea, S; Motran, CC; Stempin, CC; Volpini, X | 1 |
| Aghamiri, H; Asgarpanah, J; Shafaroodi, H | 1 |
| Fujii, W; Inamochi, A; Kitamoto, K; Kuroda, M; Miyai, T; Ouchi, Y; Taketani, Y; Toyono, T; Usui, T; Yamagami, S | 1 |
| Ando, M; Asano, S; Hayashi, Y; Iinuma, T; Iwata, K; Kanno, K; Kimura, Y; Koyama, R; Kubo, A; Lee, J; Ohara, K; Sakanashi, K; Shinoda, M; Soma, K; Sugawara, S | 1 |
| Abdel Hafez, SMN; Abdel-Hakeem, EA; Abdel-Hamid, HA | 1 |
| Choe, CU; Jensen, M; Müller, C; Schwedhelm, E; Zeller, T | 1 |
| Gan, Q; Tang, R; Wang, F; Wang, G; Wang, X; Yang, C; Zhang, F; Zhang, J; Zhang, Q; Zhao, L; Zhao, S; Zhou, J | 1 |
| Amarger, V; Bourdon, A; Darmaun, D; Ferchaud-Roucher, V; Hannigsberg, J; Misbert, E; Tran, TN; Winer, N | 1 |
| Bai, F; Chen, H; Chen, L; Cheng, Z; Dong, Y; Fan, Z; Jin, S; Jin, Y; Lin, J; Liu, C; Pan, X; Shi, J; Tian, Z; Wei, Y; Wu, W | 1 |
| Alizamani, E; Ghorbanzadeh, B; Mansouri, MT; Naserzadeh, R | 1 |
| Adachi, H; Fujita, H; Ito, C; Katsuno, M; Minakawa, EN; Mochizuki, H; Nagai, Y; Okamoto, Y; Onodera, O; Ozawa, D; Popiel, HA; Saito, Y; Saitoh, Y; Shiraki, K; Sobue, G; Suzuki, M; Tada, M; Takahashi, T; Takahashi, Y; Takeda, A; Takeuchi, T; Toda, T; Wada, K; Watase, K; Yagihara, H; Yamamoto, K; Yamane, H | 1 |
| David, H; Hoang, JD; Salavatian, S; Swid, MA; Vaseghi, M; Yamaguchi, N | 1 |
| Bai, J; Cai, X; Chen, X; Deng, S; Ginhoux, F; Gu, J; Li, Q; Liu, Z; Lou, F; Niu, L; Shi, YL; Sun, L; Sun, Y; Tao, W; Wang, H; Wang, Z; Wu, Z; Xu, Z; Yin, Q; Zhou, H | 1 |
| Atan, D; Barrington, AF; Butler, MJ; Coward, RJM; Graham, M; Heesom, KJ; Herbert, E; Hurcombe, JA; Ju, W; Kretzler, M; Lay, AC; Lewis, PA; McArdle, CA; Mountjoy, E; Nair, V; Neal, CR; Nelson, RG; Perrett, RM; Ramnath, RD; Satchell, SC; Welsh, GI; Wilson, MC | 1 |
| Ahmadi-Zeidabadi, M; Jeddi, S; Kohlmeier, KA; Mohammadi, F; Shabani, M | 1 |
| Carrión, J; Domínguez-Bernal, G; Jiménez, M; Jiménez, MÁ; Martínez-Rodrigo, A; Mas, A; Molina, R; Orden, JA | 1 |
| Cai, S; Ding, Y; Lan, R; Li, J; Li, Z; Liu, P; Lu, J; Wang, J; Wang, P; Xie, T; Ye, J | 1 |
| Armstead, EA; Bayne, KV; Converso-Baran, KL; Cuttitta, AJ; D'Alecy, LG; Garbincius, JF; Merz, LE; Michele, DE; Schrade, S; Whitesall, SE | 1 |
| Huang, D; Tan, B; Wang, C; Wang, Y; Wu, M; Ye, C; Yuan, M; Zou, Y | 1 |
| Abadir, PM; Chung, T; de Cabo, R; Ferrucci, L; Hoke, A; Joca, H; Khadeer, M; Le, A; Lovett, J; Moaddel, R; Tian, J; Walston, J; Ward, C; Westbrook, R; Xue, QL; Yang, H | 1 |
| Han, CK; Kang, HS; Kim, K; Kim, M; Kim, SH; Kim, TH; Kwak, D; Kwon, YS; Lee, YC; Lee, YS; Lee, YY; Oh, JW; Park, YC; Rhee, MH; Saba, E; Shin, HJ; Woo, SM; Yang, WK | 1 |
| Engel, H; Gazyakan, E; Germann, G; Hirche, C; Reichenberger, MA; Urbach, O | 1 |
| Alexander, RT; Ball, RO; Beggs, MR; Lansing, M; Nation, PN; Pencharz, PB; Rafii, M; Slim, G; Turner, JM; Wales, PW; Wizzard, P | 1 |
| Balenovic, I; Blagaic, AB; Cilic, M; Drmic, D; Filipcic, I; Ilic, S; Kokot, A; Seiwerth, S; Sikiric, P; Strbe, S; Tvrdeic, A; Vukojevic, J; Zemba Cilic, A; Zemba, M; Zoricic, Z | 1 |
| Chen, S; Dong, J; Glynn, S; Li, S; Li, Y; Lu, B; Snyder, M; Tantray, I; Vogel, H; Wu, Z | 1 |
| López, V; Moraga, FA; Uribe, E | 1 |
| Abdelzaher, WY; Ahmed, SM; Batiha, GE; Kamel, MY; Marraiki, N; Welson, NN | 1 |
| Abdulla, MH; Ahmad, A; Ahmad, FU; Akhtar, S; Chia, TY; Johns, EJ; Khan, NAK; Mei, HY; Murugaiyah, V; Sattar, MA | 1 |
| Altiné-Samey, R; Antier, D; Balageas, AC; Beaufils, E; Chalon, S; Dufour-Rainfray, D; Emond, P; Foucault-Fruchard, L; Mavel, S | 1 |
| Caldovic, L; Haskins, N; McNutt, M; Morizono, H; Senkevitch, E; Sonaimuthu, P; Tuchman, M; Uapinyoying, P | 1 |
| Liu, H; Rosen, CJ | 1 |
| Ahmadi, H; Amini, A; Bayat, M; Chien, S; Ghoreishi, SK; Mostafavinia, A; Rezaei, F; Sajadi, E | 1 |
| Cha, IJ; Chung, CG; Ha, CM; Kim, ES; Kim, HJ; Kim, J; Kim, YH; Ko, BS; Lee, SB; Park, JH; Park, SS | 1 |
| Anderson, EN; Basso, M; Caricasole, A; Grant, RA; Hernández, IH; Lucas, JJ; Migazzi, A; Pandey, UB; Pennuto, M; Ratovitski, T; Roccuzzo, M; Ross, CA; Saudou, F; Scaramuzzino, C; Tosatto, L; Tripathy, D; Virlogeux, A; Zuccato, C | 1 |
| Ballhausen, D; Barroso, M; Braissant, O; Caterino, M; Costanzo, M; Cudalbu, C; Cudré-Cung, HP; Feichtinger, RG; Gersting, SW; Gonzalez Melo, M; Häberle, J; Mayr, JA; Poms, M; Remacle, N; Roux, C; Rüfenacht, V; Ruoppolo, M | 1 |
| Bensellam, M; Enriquez, R; Gao, H; Gao, Z; Gou, L; Haigh, JJ; Herzog, H; Hughes, W; Ip, CK; Lau, J; Laybutt, DR; Lee, K; Loh, K; Nobis, M; Shi, YC; Timpson, P; Wang, QP; Wu, Q; Xia, Z; Yan, C; Zeng, T; Zhang, L | 1 |
| Adams, KJ; Colton, CA; Gottschalk, WK; Millington, DS; Moseley, MA; Thompson, JW; Wilson, JG | 1 |
| Cantrell, R; Crowther, RR; Janssen, EM; Lehn, MA; McKell, MC; Qualls, JE; Robillard, MC; Schmidt, SM | 1 |
| Abdelmageed, ME; Nader, MA; Zaghloul, MS | 1 |
| Cai, Y; Chau, KC; Chow, DTL; Chow, JPH; Chung, SHK; Kwok, SY; Lam, JYT; Lee, WL; Leung, YC; Leung, YO; Lu, X; Wong, RMH; Yang, LL; Yuen, CH | 1 |
| Granica, S; Koshovyi, O; Kostenko, Y; Krasilnikova, O; Kravchenko, G; Piwowarski, JP; Stremoukhov, O; Zagayko, A | 1 |
| Dutt, K; Dutton, SBB; Escayg, A; Goldin, AL; Helmers, S; Papale, LA | 1 |
| Hsu, CN; Tain, YL | 1 |
| Jang, JH; Jin, CL; Kim, SJ; Oh, GT; Wu, YN; Zhang, YH; Zhao, ZH | 1 |
| Bilkey, DK; Jing, Y; Liu, P; Zhang, H; Zhang, J | 1 |
| Ernst, L; Giesert, F; Glasl, L; Hölter, SM; Piccoli, G; Stautner, C; Vogt Weisenhorn, DM; Wurst, W; Zerle, J; Zimprich, A | 1 |
| Cao, J; Lei, T; Liu, S; Lu, Z; Shi, L; Wang, H; Zhao, C | 1 |
| Anaeigoudari, A; Beheshti, F; Hosseini, M; Nosratabadi, R; Soukhtanloo, M | 1 |
| Banerjee, S; Barlass, U; Cheema, H; Dawra, RK; Dixit, A; Dudeja, V; Dutta, R; George, J; Giri, B; Meng, J; Roy, S; Saluja, AK; Sareen, A; Yuan, Z | 1 |
| Aroeira, RI; Meireles, P; Mendes, AM; Mounce, BC; Prudêncio, M; Staines, HM; Vignuzzi, M | 1 |
| Horvath, A; Ostorhazi, E; Otvos, L; Szabo, D | 1 |
| Han, Y; Kong, L; Liu, L; Liu, Z; Sun, H; Wang, X; Yu, J; Zhang, A | 1 |
| Chen, SR; Jin, XG; Pan, HL | 1 |
| Atzler, D; Böger, RH; Chen, P; Chen, Y; Fassett, J; Guo, H; Hu, X; Kwak, D; Liu, X; Lu, Z; Schwedhelm, E; Wang, H; Xu, X; Yue, W; Zhang, P | 1 |
| Alam, HB; Chen, E; Chong, W; Deng, Q; Li, Y; Liang, Y; Liu, B; Mobley, J; Pan, B; Tewari, M; Wang, T; Wang, Y | 1 |
| Bauk, L; Drmic, D; Ilic, S; Kolenc, D; Luetic, K; Seiwerth, S; Sever, M; Sikiric, P; Suran, J; Zenko Sever, A | 1 |
| Athanasiadis, D; Kapelouzou, A; Lazaris, AM; Liakakos, T; Machairas, A; Martikos, G; Moulakakis, K; Paspala, A; Peroulis, M; Vasdekis, S | 1 |
| Dong, DW; Fina, M; Han, X; Kashina, A; Kurosaka, S; Lee, VM; Leu, NA; Sterling, S; Wang, J; Yates, JR | 1 |
| Cai, W; Li, H; Li, Y; Ma, Y; Niu, X; Yang, G; Yang, N; Zhang, X; Zhao, Y; Zhou, X | 1 |
| Nishihira, J; Ohkawara, T; Takeda, H | 1 |
| Černe, D; Drevenšek, G; France Štiglic, A; Janić, M; Jerin, A; Lunder, M; Marc, J; Šabovič, M; Skitek, M | 1 |
| Cabral, P; Dagher, PC; Dube, S; El-Achkar, TM; Hato, T; Maier, BF; McClintick, J; Pay, SL; Plotkin, Z; Yoshimoto, M; Zollman, A | 1 |
| Coskun, CN; Demirel-Yilmaz, E; Savci, V; Usanmaz, SE | 1 |
| Song, Y; Tang, C; Yin, C | 1 |
| Beineke, A; Goldmann, O; Medina, E | 1 |
| Lamitina, ST; Monaghan, J; Pandey, UB; Rudich, P; Snoznik, C; Watkins, SC | 1 |
| Biczo, G; Dawson, D; Elperin, J; French, SW; Gorelick, FS; Gretler, S; Gukovskaya, AS; Gukovsky, I; Hegyi, P; Husain, SZ; Lotshaw, E; Lugea, A; Malla, SR; Mareninova, OA; Rakonczay, Z; Ruchala, P; Shalbueva, N; Vegh, ET; Wen, L; Whitelegge, J | 1 |
| Lu, XY; Sui, GG; Sun, ZL; Xiao, HB | 1 |
| Brown, JA; Browning, C; Heise, MT; Jones, JE; Lim, JK; Long, KM; Moorman, N; Morrison, CR; Peck, KM; Sanders, W; Thurlow, LR; Vincent, H; Whitmore, AC | 1 |
| Duan, LF; Fan, JW; Liu, F; Wu, N; Xin, JQ; Xu, XF; Zhang, H; Zhang, XQ; Zhu, LJ | 1 |
| Bahremand, T; Dehpour, AR; Noorian, AR; Payandemehr, B; Payandemehr, P; Riazi, K; Sharifzadeh, M | 1 |
| Bian, Y; Chen, L; Li, J; Lu, J; Ma, C; Su, L; Wang, T | 1 |
| Alboghobeish, S; Amirgholami, N; Ghorbanzadeh, B; Houshmand, G; Mansouri, MT; Naghizadeh, B | 1 |
| Abbott, M; Abdi, M; Chauhan, N; Chin, M; Fucci, QA; Halim, A; Handy, DE; Lim, K; Loscalzo, J; Lu, TS; Mistri, M; Pang, P; Proctor, B; Siedlecki, AM; Wang, B; Yin, W | 1 |
| Carbajosa, S; Chillón-Marinas, C; Colombet, D; Fresno, M; Gea, S; Gironès, N; Maza, MC; Poveda, C; Rodríguez-Angulo, HO | 1 |
| Antunovic, M; Bilic, Z; Drmic, D; Duzel, A; Gojkovic, S; Kasnik, K; Knezevic, M; Kokot, A; Kolovrat, M; Kralj, T; Krezic, I; Lojo, N; Malekinusic, D; Samara, M; Seiwerth, S; Sever, M; Sikiric, P; Siroglavic, M; Vidovic, T; Vlainic, J; Vrdoljak, B; Vukojevic, J | 1 |
| Calderon, JLC; King, LE; King, SJ; Ledray, AP; Love, R; Nandini, S; Pasos, J; Sabblah, TT | 1 |
| Bragazzi Cunha, J; Gu, S; Iyer, S; Moons, D; Omary, MB; Park, MJ; Pipe, SW; Shah, YM; Simeone, DM; Williams, JA; Xue, X | 1 |
| Bibikova, E; Danilova, N; Lin, S; Sakamoto, KM; Wilkes, M; Youn, MY | 1 |
| El-Ashmawy, NE; El-Bahrawy, HA; Hamada, OB; Khedr, NF | 1 |
| Cinar, R; Erdelyi, K; Gao, B; Guillot, A; Haskó, G; Jourdan, T; Kunos, G; Matyas, C; Mehal, A; Nemeth, BT; Pacher, P; Paloczi, J; Rosen, S; Stillman, IE; Varga, ZV; Xiang, X; Zsengeller, ZK | 1 |
| Alberti, JM; Baloh, RH; Biris, N; Dorn, GW; Franco, A; Gavathiotis, E; Janetka, JW; Kitsis, RN; Knight, WC; Krezel, AM; Mochly-Rosen, D; Rocha, AG; Rumsey, JM; Townsend, RR; Zacharioudakis, E | 1 |
| Boubred, F; Buffat, C; Charpiot, P; Dignat-George, F; Fromonot, J; Grandvuillemin, I; Lamy, E; Peyter, AC; Sabatier, F; Simeoni, U; Simoncini, S; Yzydorczyk, C | 1 |
| Abraham, WC; Bergin, DH; Jing, Y; Liu, P; Mockett, BG; Zhang, H | 1 |
| Hsieh, KF; Pai, MH; Shih, JM; Shih, YM; Yeh, SL | 1 |
| Alam, HB; Chen, E; Deng, Q; Duan, X; Li, Y; Liang, Y; Liu, B; Pan, B; Tian, Y; Wang, Y; Williams, AM; Zhang, J | 1 |
| Hu, DD; Huang, JF; Li, F; Xiao, XR; Yang, R; Zhao, Q | 1 |
| Eringa, EC; Gam, Z; Hoenderop, JG; Juni, RP; Kwekkeboom, RFJ; Richards, WG; Ter Wee, PM; van Loon, EPM; van Poelgeest, EM; Verkaik, M; Vervloet, MG | 1 |
| Al Shamy, G; Campeau, PM; Chen, S; Chen, Y; Cherian, L; Goodman, C; Jiang, MM; Jin, Z; Kron, B; Lee, B; Madan, S; Munivez, E; Ratan, RR; Robertson, C; Sun, Q | 1 |
| Ghosh, M; Golestani, R; Gona, K; Han, J; Jung, JJ; Kim, HY; Razavian, M; Sadeghi, MM; Toczek, J; Wu, TL; Ye, Y; Zhang, J | 1 |
| Hegyi, E; Jancsó, Z; Sahin-Tóth, M | 1 |
| Das, PP; Hii, L; Law, RHP; Lin, W; Mann, JR; Steer, DL; Udugama, M; Voon, HPJ; Wong, LH | 1 |
| Boivin, G; Checkmahomed, L; Couture, C; Hamelin, MÈ; Jandrot-Perrus, M; Lê, BV; Venable, MC | 1 |
| Barančík, M; Berenyiová, A; Dovinová, I; Hrabárová, E; Jansen, E; Kvandová, M; Majzúnová, M | 1 |
| Didelija, IC; Marini, JC; Mohammad, MA; Wang, X; Yuan, Y | 1 |
| Etrych, T; Fang, J; Imamura, T; Islam, W; Maeda, H; Subr, V; Ulbrich, K | 1 |
| Kaygısız, B; Kaygısız, Z; Kutlay, Ö | 1 |
| Barupal, DK; Chmiel, KJ; Hwang, VJ; Ishimaru, T; Jen, KY; Li, X; Mahjoub, MR; Shim, K; Stewart, BJ; Trott, JF; Weiss, RH; Zhou, JX | 1 |
| Chang, Z; Chen, H; Chen, S; Chen, X; Guo, J; He, J; He, L; Hu, Z; Lai, L; Li, Z; Liu, W; Lou, J; Qi, H; Shan, H; Shi, Y; Sun, X; Wang, Q; Xiao, L; Xu, C; Yang, B; Yang, C; Yang, W; Yang, Z; Zhang, F; Zhang, H; Zhao, X; Zheng, F; Zheng, W; Zhou, XJ | 1 |
| Brito, BM; Gobira, PH; Joca, SRL; Sartim, AG | 1 |
| Anczurowski, M; Arrowsmith, CH; Butler, MO; Guo, T; Hirano, N; Kagoya, Y; Matsunaga, Y; Murata, K; Saijo, H; Saso, K; Sugata, K; Wang, CH | 1 |
| Ding, L; Gao, X; Hu, J; Yu, S | 1 |
| Blair, CA; Campbell, KS; Holewinski, RJ; Kirk, JA; Li, A; Martin, TG; Moravec, CS; Papadaki, M; Previs, SB; Stachowski, MJ; Van Eyk, JE; Warshaw, DM | 1 |
| Chen, JR; Huang, WC; Ko, J; Yang, HY; Yeh, WJ | 1 |
| Burova, LA; Freidlin, IS; Golovin, AS; Karaseva, AB; Kudryavtsev, IV; Serebriakova, MK; Sokolov, AV; Starikova, EA; Suvorov, AN; Vasilyev, KA; Vasilyev, VB; Voynova, IV | 1 |
| Chlopicki, S; Jasztal, A; Kij, A; Kus, K; Stojak, M; Walczak, M; Zakrzewska, A | 1 |
| Fujisawa, Y; Gohda, T; Horikoshi, S; Kobayashi, T; Nishiyama, A; Shiota, S; Sugaya, T; Suzuki, Y; Takahashi, K; Ueda, S | 1 |
| Amic, E; Amic, F; Bilic, Z; Boban Blagaic, A; Drmic, D; Horvat Pavlov, K; Klicek, R; Kokot, A; Krezic, I; Milkovic Perisa, M; Pajtak, A; Peklic, M; Rakic, M; Seiwerth, S; Sikiric, P; Tvrdeic, A; Vidovic, T; Zizek, H; Zovak, M | 1 |
| Hunt, JB; Jing, Y; Lee, DC; Liu, P; Sandusky-Beltran, LA; Vemula, P; Zhang, H | 1 |
| Antunovic, M; Drmic, D; Horvat Pavlov, K; Jeyakumar, J; Malekinusic, D; Milkovic Perisa, M; Ruzman, J; Samara, M; Seiwerth, S; Sikiric, P; Vidovic, T; Vrdoljak, B | 1 |
| Antipov, E; Brennan, AM; Charbonneau, MR; Dagon, Y; Degar, AJ; Denney, WS; Isabella, VM; Kotula, JW; Kurtz, CB; Miller, PF; Millet, YA; Perreault, M; Puurunen, MK; Wagner, DA; West, KA | 1 |
| Abekura, Y; Arai, D; Ikeda, H; Ishii, A; Miyamoto, S; Nishi, H; Tabata, Y | 1 |
| Lakshminrusimha, S; Nair, J | 1 |
| Caparros-Wanderley, W; Chang, YS; Combes, V; Gramaglia, I; Grau, G; Stins, MF; van der Heyde, HC; Velez, J | 1 |
| Chen, XX; Feng, XL; Gao, L; Ren, HL; Wang, JL; Xiao, JH; Zhang, JH | 1 |
| Ding, J; Fu, K; Gan, W; Han, R; Han, X; Jiang, K; Li, D; Wu, J; Zhang, L | 1 |
| Ankrum, JA; Cao, HJ; Cheng, D; Ding, WX; Li, M; Qian, Q; Rauckhorst, AJ; Savage, K; Taylor, EB; Xiao, Y; Yang, L; Zhang, Z | 1 |
| Araujo, NS; Claudino, MA; Nascimento, LS; Priolli, DG; Priviero, FBM; Rocha, T; Tedesco, LM | 1 |
| Ahmad, S; Bhatia, K; Ducruet, AF; Kindelin, A | 1 |
| Chang, SF; Godec, A; Hawkins, WG; Hirbe, AC; Prudner, BC; Rathore, R; Robinson, AM; Van Tine, BA | 1 |
| Amador-Martínez, I; Barrera-Chimal, J; Bobadilla, NA; Cortés-González, C; Pérez-Villalva, R; Uribe, N | 1 |
| Coleman, DN; Guo, S; Loor, JJ; Peng, A; Wang, H; Wang, M; Yu, Y; Zhang, H | 1 |
| Berrett, KC; Bomalaski, JS; Chalishazar, MD; Cosulich, SC; DeBerardinis, RJ; Gertz, J; Guthrie, MR; Hu, Z; Huang, F; Ingolia, NT; Ireland, AS; Kudla, M; Lee, Y; Lum, DH; Modzelewska, K; Mukhopadhyay, A; Oliver, TG; Schuman, SS; Vahrenkamp, JM; Wait, SJ; Wang, G | 1 |
| Chen, YY; He, LY; Liu, GY; Liu, H; Liu, JS; Peng, XF; Sun, L; Xiao, L | 1 |
| Atalay, Y; Hirfanoglu, I; Karabulut, R; Onal, E; Soylemezoglu, F; Turkyilmaz, C; Turkyilmaz, Z | 1 |
| da Silva, KA; da Silva, SBB; de Andrade Bernal Fagiani, M; de Azevedo Mello, F; de Souza Reis, LSL; Fluminhan, A; Giozo, PFI; Gonçalves, GV; Pereira, LG; Santarem, CL; Tsujigushi, LK; Yabuki, D | 1 |
| Chen, X; Qin, S; Zhao, X; Zhou, S | 1 |
| Bai, Y; Becker, S; Cortes-Burgos, LA; Croll, SD; Eckersdorff, MM; Macdonald, LE; Ruiz, HH | 1 |
| El-Agamy, DS; El-Kashef, DH; Shaaban, AA | 1 |
| He, H; Jiang, H; Li, X; Liu, X; Liu, Y; Wang, H; Wang, S; Yuan, L; Zhang, W | 1 |
| Caron, MG; Dzirasa, K; Kumar, S; Nicolelis, MA; Sachs, BD | 1 |
| Billiar, TR; Morris, SM; Ochoa, JB; Pribis, JP; Rodriguez, PC; Vodovotz, Y; Zhu, X | 1 |
| Brzozowska, I; Brzozowski, T; Hess, T; Kania, J; Konturek, PC; Konturek, SJ; Kwiecien, S; Pawlik, M; Reiter, RJ; Targosz, A | 1 |
| Ayten, R; Cetinkaya, Z; Girgin, M; Kanat, BH; Ozercan, IH; Ustundag, B; Yenicerioglu, A | 1 |
| Hara, T; Ide, S; Kaneda, K; Koseki, K; Maruyama, C; Minami, M; Naka, T; Ohno, A; Tamano, R; Yoshioka, M | 1 |
| Bedir, YK; Caliskan, G; Can, MM; Kankaya, Y; Karaaslan, O; Silistreli, OK; Sonmez, E | 1 |
| Abbolhasani, K; Nasehi, M; Piri, M; Zarrindast, MR | 1 |
| Akhtar, MN; Akira, A; Israf, DA; Kamaldin, MN; Lajis, N; Ming-Tatt, L; Mohamad, AS; Perimal, EK; Sulaiman, MR | 1 |
| Aggarwal, T; Casci, I; Fackelmayer, FO; Lanson, NA; Maltare, A; Milioto, C; Monaghan, J; Pandey, UB; Pennuto, M; Scaramuzzino, C | 1 |
| Bananej, M; Piri, M; Shahab, Z; Zahmatkesh, M; Zarrindast, MR | 1 |
| Casella-Filho, A; Chagas, AC; da-Luz, PL; Dourado, PM; Landim, MB | 1 |
| Betz, B; Böger, RH; Kniepert, J; Kress, T; Möller-Ehrlich, K; Sauvant, C; Schneider, R; Schwedhelm, E; Wanner, C | 1 |
| Blom, HJ; Castro, R; de Vriese, AS; Esse, R; Florindo, C; Imbard, A; Rocha, MS; Smulders, YM; Tavares de Almeida, I; Teerlink, T | 1 |
| Chuman, H; Ishiai, M; Kawano, N; Maekubo, T; Nao-I, N; Osako, T | 1 |
| Chakraborti, A; Gulati, K; Ray, A | 1 |
| Cooke, JP; Erlanson, DA; Ghebremariam, YT; Lee, JC; Leiper, J; LePendu, P; Shah, NH; Slaviero, A | 1 |
| Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR | 1 |
| Ming, XF; Montani, JP; Xiong, Y; Yang, Z; Yu, Y | 1 |
| Andersen, JM; Bügel, S; de Courten, B; Dragsted, LO; Hedegaard, RV; Nielsen, J; Poulsen, MW; Skibsted, LH | 1 |
| Bartholomae, CC; Gui, T; Hu, G; Kafri, T; Kutschera, I; Monahan, PE; Schmidt, M; Suwanmanee, T; von Kalle, C | 1 |
| Fernandez-Godino, R; Garland, DL; Harnly, JM; Kaur, I; Lambris, JD; Pierce, EA; Speicher, DW; Speicher, KD | 1 |
| Chen, S; Chen, X; Ding, X; Dong, N; Gao, W; Li, L; Li, S; Rong, J; Shao, F; Sun, L; Yao, Q; Zhang, L | 1 |
| Guo, YY; Hage, FG; Hilgers, RH; Pacurari, M; Xing, D; Yang, Z | 1 |
| Adamo, RF; Alferiev, IS; Chorny, M; Fishbein, I; Forbes, SP; Levy, RJ | 1 |
| Buchan, AM; Sutherland, BA | 1 |
| Caldwell, RB; Caldwell, RW; Kondrikov, D; Nunes, KP; Su, Y; Toque, HA; Webb, RC; Xu, Z; Yao, L | 1 |
| Cao, Y; Chen, Y; He, J; Huang, S; Li, Z; Liu, L; Sun, L; Xu, Z; Yang, L; Zhang, L | 1 |
| Han, X; Liu, WH; Yin, DX; Zhang, DL; Zhang, QD | 1 |
| Atzler, D; Baldus, S; Benndorf, RA; Blankenberg, S; Böger, RH; Carter, AM; Choe, CU; De Deyn, PP; Gerloff, C; Grant, PJ; Heerschap, A; Isbrandt, D; Lackner, K; Lüneburg, N; Magnus, T; Marescau, B; Müller, C; Nabuurs, C; Ojeda, F; Schwedhelm, E; Simova, O; Stockebrand, M; Streichert, T; Wild, PS; Zeller, T | 1 |
| Lee, L; Nickla, DL; Totonelly, K | 1 |
| Czopek, A; Edmunds, MC; Kluth, DC; Wigmore, SJ | 1 |
| Aziz, M; Belmonte, L; Beutheu, S; Bôle-Feysot, C; Coëffier, M; Déchelotte, P; Galas, L; Guérin, C; Ouelaa, W; Tennoune, N | 1 |
| Aggarwal, S; Black, SM; Bogatcheva, NV; Catravas, JD; Dimitropoulou, C; Gorshkov, BA; Gross, CM; Jezierska-Drutel, AJ; Kumar, S; Lu, Q; Lucas, R; Sharma, S; Sridhar, S; Verin, AD | 1 |
| Cannon, SC; Mi, W; Wu, F | 1 |
| Caparon, MG; Cusumano, ZT; Watson, ME | 1 |
| Chen, YH; Hsiao, CC; Hsu, LS; Lee, CH; Lo, HC | 1 |
| Cui, L; Guo, W; Li, C; Li, Y; Liu, B; Lv, W; Pan, X; Wang, Y; Yan, S; Zhang, J | 1 |
| Bai, J; Gao, C; Sun, Y; Tang, Z; Wang, J; Wang, N; Xing, G | 1 |
| Bansal, P; Bartlett, DL; Billiar, TR; Bonaroti, J; Cao, L; Chang, EB; Chen, R; Fan, XG; Hou, W; Kang, R; Lotze, MT; Lu, B; Tang, D; Tracey, KJ; Tsung, A; Wang, H; Wang, Q; Whitcomb, DC; Yan, Z; Zeh, HJ; Zhang, Q; Zhu, X | 1 |
| Balla, Z; Hegyi, P; Iványi, B; Kui, B; Pallagi, P; Rakonczay, Z; Takács, T; Végh, ET; Venglovecz, V | 1 |
| Mori, K; Saitoh, W; Takasaki, W; Watanabe, K; Yamauchi, S | 1 |
| Baekelandt, V; Lobbestael, E; Van den Haute, C; Van der Perren, A; Van Rompuy, AS | 1 |
| Azadi, S; Burnett, JL; Chakraborty, D; Conley, SM; Fliesler, SJ; Naash, MI; Stuck, MW | 1 |
| Blom, HJ; Castro, R; Davids, M; Esse, R; Florindo, C; Gupta, S; Imbard, A; Kruger, WD; Quinlivan, EP; Tavares de Almeida, I; Teerlink, T | 1 |
| Alcantara, R; Baltgalvis, KA; Claypool, MD; Friera, AM; Godinez, G; Goff, D; Gururaja, T; Hansen, D; Hitoshi, Y; Jenkins, Y; Kinsella, TM; Lang, W; Lau, D; Li, W; Li, Y; Markovtsov, V; McCaughey, K; McLaughlin, J; Nguyen, H; Pan, A; Park, G; Payan, DG; Shaw, SJ; Singh, BK; Singh, R; Smith, IJ; Sun, TQ; Uy, G; White, K | 1 |
| Kumar, A; Rinwa, P | 1 |
| Rouse, RL; Zhang, J | 1 |
| Chen, YC; Huang, LT; Sheen, JM; Tain, YL | 1 |
| Benoit, E; Bich, C; Brunelle, A; Cancela, JM; Consolaro, F; de la Porte, S; Israël, M; Lanchec, E; Roulot, M; Touboul, D; Vianello, S | 1 |
| Bogdanski, P; Lis, I; Musialik, K; Suliburska, J; Szulinska, M | 1 |
| da Silva, LA; da Silva, WC; dos Santos, FS; Grassiolli, S; Malfatti, CR; Pochapski, JA; Raczenski, A | 1 |
| Cordeiro, RC; Costa, AM; de Lucena, DF; de Sousa, FC; Macêdo, D; Nobre Júnior, HV; Quevedo, J; Tomaz, VS; Vale, ML; Vasconcelos, SM | 1 |
| Cervera, A; Chamorro, Á; de la Rosa, X; Durduran, T; Justicia, C; Kristoffersen, AK; Planas, AM; Valdés, CP; Varma, HM | 1 |
| Miller, CB; Szwergold, BS | 1 |
| Arend, M; Cordasic, N; Hilgers, KF; Jacobi, J; Maas, R | 1 |
| Biojone, C; Hiroaki-Sato, VA; Joca, SR; Sales, AJ | 1 |
| Baek, JH; Rubinstein, M; Scheuer, T; Trimmer, JS | 1 |
| Aboulkassim, T; Hamel, E; Imboden, H; Lecrux, C; Nicolakakis, N; Ongali, B; Papadopoulos, P; Rosa-Neto, P; Tong, XK | 1 |
| Bolon, B; Price, J; Rebelo, AP; Silva, JP; Strickland, AV; Wen, R; Zhang, F; Züchner, S | 1 |
| Khalili, A; Khosravi, MB; Nekooeian, AA | 1 |
| Moezi, L; Mousavi, Z; Sattarinezhad, E; Shafaroodi, H; Sheikhnouri, K | 1 |
| Bode-Böger, SM; Brilloff, S; Hohenstein, B; Jabs, N; Jarzebska, N; Kittel, A; Maas, R; Martens-Lobenhoffer, J; Rodionov, RN; Weiss, N | 1 |
| Ming, XF; Montani, JP; Rajapakse, AG; Yang, Z; Yu, Y | 1 |
| Andersson, M; Bergström, S; Björk, R; Engström, P; Fahlgren, A; Moritz, T; Nelson, M; Normark, J | 1 |
| Abu el Maaty, MA; El-Maraghy, SA; Fahim, AT; Gad, MZ; Hamdy, MA | 1 |
| Borkar, CD; Desai, SJ; Kokare, DM; Nakhate, KT; Subhedar, NK | 1 |
| Arikan-Ayyildiz, Z; Bagriyanik, A; Firinci, F; Karaman, M; Karaman, O; Kiray, M; Uzuner, N; Yilmaz, O | 1 |
| Benoit, E; Boerio, D; Bouyon, S; de la Porte, S; Fromes, Y; Herbin, M; Roulot, M; Sebrié, C; Vianello, S | 1 |
| Duque-Correa, MA; Hurwitz, R; Kaufmann, SH; Kosmiadi, GA; Kühl, AA; Murray, PJ; Qualls, JE; Rao, M; Reece, ST; Rodriguez, PC; Schommer-Leitner, S; Weiner, J; Zedler, U | 1 |
| Berardo, C; Bianchi, A; Di Pasqua, LG; Ferrigno, A; Richelmi, P; Rizzo, V; Vairetti, M | 1 |
| Caglayan, EK; Caglayan, K; Cinar, H; Göcmen, AY; Güngör, B; Polat, MF; Seckin, L; Seckin, S | 1 |
| Baylis, C; Cunningham, MW; Sasser, JM | 1 |
| Dai, G; Liu, J; Liu, YK; Wang, X; Wang, Y; Xu, Q; Xu, X; Zhang, J; Zhang, W | 1 |
| Gao, X; Guo, F; Liu, J; Zhang, Q; Zheng, S | 1 |
| Guo, C; Lai, H; Li, J; Wang, C; Wang, L; Wang, Y; Zhu, K | 1 |
| Andreola, F; Davies, N; De Chiara, F; Garcia-Martinez, R; Habtesion, A; Jalan, R; Jover, M; Macnaughtan, J; Mehta, G; Mookerjee, RP; Oria, M; Poulton, K; Soeda, J | 1 |
| Breitinger, HG; El-Sayed, NS; Gad, MZ; Maher, A | 1 |
| Gulati, K; Joshi, JC; Ray, A | 1 |
| Amiri, S; Dehpour, AR; Haj-Mirzaian, A; Imran-Khan, M; Kordjazy, N; Mehr, SE; Rahimi Balaei, M; Shirzadian, A | 1 |
| Allen, MR; Chen, N; Granke, M; Moe, SM; Newman, CL; Nyman, JS | 1 |
| He, X; Ji, Y; Lei, T; Liu, Q; Tian, W; Wang, G; Wang, Y; Xu, H; Zhao, D | 1 |
| Farzaneh, SH; Ichii, H; Li, S; Masuda, Y; Robles, L; Stamos, MJ; Takasu, C; Vaziri, ND; Vo, K | 1 |
| Joca, S; Liebenberg, N; Wegener, G | 1 |
| Chibbar, R; Ndisang, JF | 1 |
| Lu, Z; Luo, Y; Quan, X; Wang, Y; Yue, W; Zhao, B | 1 |
| Bencsik, P; Cabrera-Fuentes, HA; Csonka, C; Ferdinandy, P; Preissner, KT; Sárközy, M; Schlüter, KD; Schreckenberg, R; Schulz, R; Steinert, I; Weber, P | 1 |
| Kek, TL; Salleh, MZ; Sani, MH; Susanti, D; Taher, M; Zakaria, ZA | 1 |
| Gierok, P; Hammerschmidt, S; Lalk, M; Mäder, U; Petruschka, L; Schulz, C | 1 |
| Belik, J; Dhaliwal, R; Grasemann, H; Ivanovska, J; Jankov, RP; Kantores, C; McNamara, PJ; Scott, JA | 1 |
| Abrantes, FA; Andrade, ME; Araújo, RS; Cardoso, VN; de Barros, PA; Fernandes, SO; Generoso, Sde V; Soares, AD | 1 |
| Anderton, RS; Brookes, LM; Clark, VW; Cross, JL; Edwards, AB; Hoffmann, K; Hopkins, RM; Knuckey, NW; Meloni, BP | 1 |
| Balla, Z; Hegyi, P; Iványi, B; Kormányos, ES; Kui, B; Pallagi, P; Rakonczay, Z; Takács, T; Vasas, B; Végh, ET; Venglovecz, V | 1 |
| Azimi, E; Dehpour, AR; Haj-Mirzaian, A; Mansouri, P; Ostadhadi, S | 1 |
| Aslan, MK; Atasoy, P; Boybeyi, O; Gunal, YD; Soyer, T | 1 |
| Achouri, Y; Gailly, P; Marbaix, E; Marie, S; Rzem, R; Schakman, O; Van Schaftingen, E; Veiga-da-Cunha, M; Vincent, MF; Wiame, E | 1 |
| Borderie, D; Bos, C; Huneau, JF; Magné, J; Mariotti, F; Mathé, V | 1 |
| Babal, P; Doka, G; Janega, P; Klimas, J; Kralova, E; Krenek, P; Kuracinova, K; Pivackova, L; Srankova, J | 1 |
| Ding, X; Han, Y; Yang, Z; Yi, Y; Yu, H | 2 |
| Brown, CM; Colton, CA; Everhart, AL; Gunn, MD; Hoofnagle, AN; Jansen, M; Kan, MJ; Lee, JE; Vitek, MP; Wilson, JG | 1 |
| Chen, G; Li, J; Lu, S; Xu, F | 1 |
| Chen, DX; Fu, LY; Gan, T; Hu, CL; Rao, CY; Wang, YC; Zhao, XY | 1 |
| Hayashi, Y; Iguchi, Y; Kitamatsu, M; Matsui, H; Michiue, H; Nishiki, T; Takenaka, F | 1 |
| Chin-Dusting, JP; Du, XJ; Johnston, T; Kaye, DM; Kiriazis, H; Rajapakse, NW | 1 |
| Dickson, G; Gait, MJ; Jarmin, SA; Lu-Nguyen, NB; Popplewell, L; Saleh, AF | 1 |
| Balasubramaniam, A; Bertin, I; Bihel, F; Boon, P; Bourguignon, JJ; Buffel, I; Coppens, J; De Kock, J; De Prins, A; Hammoud, H; Humbert, JP; Maes, V; Massie, A; Meurs, A; Portelli, J; Schmitt, M; Simonin, F; Smolders, I; Tourwe, D; Utard, V; Vanhaecke, T | 1 |
| Bachaalany, S; Bettaieb, A; Chahed, S; Griffey, S; Haj, FG; Hammock, BD | 1 |
| Lucas, ML; Mattos, AA; Rhoden, CR; Rhoden, EL; Zettler, CG | 1 |
| Anderton, RS; Edwards, AB; Fitzgerald, M; Knuckey, NW; Meloni, BP; Milani, D; O'Hare Doig, RL; Palmer, TN | 1 |
| Kolomoyets, M | 1 |
| Cang, X; Fan, Y; Hu, G; Hu, Y; Ni, J; Qiu, L; Wan, R; Wang, S; Wang, X; Xiao, W; Xing, M; Xiong, J; Yin, G; Yu, G | 1 |
| Corrêa da Silva, JA; da Silva, LM; de Souza, MM; Holzmann, I; Steimbach, VM | 1 |
| Blandini, F; Demartini, C; Ferrigno, A; Greco, R; Mangione, AS; Nappi, G; Tassorelli, C; Vairetti, M; Zanaboni, A | 1 |
| Hartman, H; Hwaiz, R; Luo, L; Merza, M; Mörgelin, M; Rahman, M; Regner, S; Renström, E; Thorlacius, H; Zhang, E | 1 |
| Fujimura, M; Ito, A; Kanoke, A; Kure, S; Morita-Fujimura, Y; Niizuma, K; Sakata, H; Sato-Maeda, M; Tominaga, T | 1 |
| Katona, LI | 1 |
| Alters, SE; Burrage, LC; Elsea, SH; Frankel, AE; Georgiou, G; Jiang, MM; Johnson, DE; Lee, BH; Nagamani, SC; Rowlinson, SW; Stone, E; Sun, Q | 1 |
| Arakawa, S; Kida, Y; Marumo, K; Nishizawa, T; Okabe, H; Saito, M; Seki, A | 1 |
| Ackerman, H; Alkaitis, MS; Billker, O; Casals-Pascual, C; Chertow, JH; Conway, DJ; Correa, S; Cunnington, AJ; Ebonyi, AO; Ikeda, AK; Jayasooriya, S; Nardone, G; Njie, M; Okebe, J; Walther, M | 1 |
| Arslan, S; Basuguy, E; Bozdag, Z; Ibiloglu, I; Kaplan, I; Okur, MH; Turkoglu, A; Uluca, U; Zeytun, H | 1 |
| Closs, EI; Daiber, A; Förstermann, U; Gericke, A; Habermeier, A; Horke, S; Li, H; Mikhed, Y; Münzel, T; Reifenberg, G; Xia, N | 1 |
| Li, X; Li, Z; Lu, B; Yu, C; Yu, X; Zhu, H; Zhu, S | 1 |
| Abkhoo, A; Amiri, S; Boojar, MM; Dehpour, AR; Delazar, S; Hassanipour, M; Ostadhadi, S; Rahimi, N; Shirzadian, A | 1 |
| Alfred, MO; Li, X; Liu, JL; Luo, C; Wang, M; Wu, MY; Yang, MQ; Yu, LT; Zhang, J; Zhang, XQ | 1 |
| Jacobsen, J; Kuminek, G; Ludka, FK; Molz, S; Olescowicz, G; Tandler, Lde F | 1 |
| He, Y; Jin, X; Li, G; Liu, Y; Wu, X; Yang, L; Yuan, H | 1 |
| Adeyemi, OO; Akinleye, MO; Ishola, IO; Owope, TE; Oyebade, R | 1 |
| Ahlbrand, R; Baccei, ML; Dolgas, CM; Rush, J; Sah, R; Schmeltzer, S; Schurdak, J; Vollmer, LL | 1 |
| Bozkırlı, BO; Ersoy, E; Gündoğdu, RH; Temel, H; Yazgan, A; Yıldırım, Z | 1 |
| Janakiram, NB; Kumar, G; Madka, V; Mohammed, A; Rao, CV | 1 |
| Abou-Fard, GM; Shafik, NM | 1 |
| Boeynaems, S; Bogaert, E; Callaerts, P; Cruts, M; Cuijt, I; De Baets, G; Gijselinck, I; Gitler, AD; Jovičić, A; Michiels, E; Robberecht, W; Rousseau, F; Scheveneels, W; Schymkowitz, J; Sieben, A; Steyaert, J; Van Broeckhoven, C; Van Damme, P; Van Den Bosch, L; Verstrepen, KJ | 1 |
| Liao, ZL; Qiu, YJ; Tan, YF; Yu, EY; Zhu, JP | 1 |
| Chang, KC; Chen, CN; Lin, RF; Shih, RL; Soung, HS; Tsai, CC; Tseng, HC; Wang, MH | 1 |
| Black, SM; Desai, AA; Fineman, JR; Fratz, S; Garcia, JG; Jacobson, JR; Kangath, A; Kellner, M; Klinger, C; Lu, Q; Qu, N; Rafikov, R; Sun, X; Wang, T; Yuan, JX | 1 |
| Al-Drees, A; Khalil, MS | 1 |
| Jia, Z; Shen, J; Shi, Y; Wu, A; Xu, C; Xu, T; Zhuang, X | 1 |
| Cerne, D; Drevensek, G; Janic, M; Jerin, A; Lunder, M; Marc, J; Sabovic, M; Skitek, M | 1 |
| Ateyya, H; El-Sherbeeny, NA; Wagih, HM | 1 |
| Bai, Y; Cao, R; Chen, Y; Du, G; He, G; Sun, L; Sun, T; Wang, F; Ye, P; Zhang, W; Zhao, R | 1 |
| Bharne, AP; Kokare, DM; Nakhate, KT; Subhedar, NK; Yedke, SU | 1 |
| Chen, L; Chu, HY; Fu, Q; Hu, MX; Liu, CJ; Qin, T; Wang, YZ; Zhang, HW; Zhang, X | 1 |
| Chen, HL; Shih, C; Su, PY | 1 |
| Cao, Y; Feng, Y; Jin, F; Zhang, Y; Zhu, X | 1 |
| Liu, XQ; Qiao, YY; Xu, CQ; Xu, HW; Zhang, Z | 1 |
| Chen, L; Huang, S; Kayoumu, A; Li, W; Liu, G; Lu, G; Qi, R; Qiu, X; Wang, Y; Xu, P | 1 |
| Arriaza, K; Böger, RH; Brito, J; Klose, H; Leon-Velarde, F; Lüneburg, N; Pena, E; Siques, P | 1 |
| Berardo, C; Croce, AC; Di Pasqua, LG; Ferrigno, A; Richelmi, P; Rizzo, V; Vairetti, M | 1 |
| Amini-Khoei, H; Dehpour, A; Hassanipour, M; Imran-Khan, M; Rahimi, N; Rezayat, SM; Shafaroodi, H; Shirzadian, A | 1 |
| Abd-Alkhalek, HA; El-Bakly, WM; El-Lithy, GM; Hamza, M; Masoud, SI; Matboli, M | 1 |
| Cho, H; Choi, D; Ho, WK; Jeon, D; Jeong, MH; Jung, CY; Jung, S; Kang, JS; Kang, K; Kim, H; Kim, HJ; Kim, KR; Kim, SH; Kim, ST; Koh, J; Koo, SH; Lee, SY; Park, JM; Park, SK; Sohn, JW; Vuong, TA; Yang, H | 1 |
| Chung, E; Ohgami, Y; Quock, RM | 1 |
| Dehpour, AR; Doustimotlagh, AH; Javadi-Paydar, M; Javadian, N; Rahimi, N | 1 |
| Andres, CR; Baranek, T; Blasco, H; Bruno, C; Corcia, P; Descat, A; Dessein, AF; Goossens, JF; Leman, S; Madji Hounoum, B; Marouillat, S; Nadal-Desbarats, L; Patin, F; Vourc'h, P | 1 |
| Andolfo, A; Bachi, A; Basso, V; Drago, D; Frezza, C; Gaude, E; Mondino, A; Musco, G; Peruzzotti-Jametti, L; Pluchino, S; Volpe, G | 1 |
| Czarnecka, A; Jaźwiec, R; Milewski, K; Zielińska, M | 1 |
| Ayala, A; Biron, BM; Chen, Y; Chung, CS; O'Brien, XM; Reichner, JS | 1 |
| Ackerman, HC; Alkaitis, MS | 1 |
| Ahmadi, SA; Chehrei, A; Darabi, MR; Jafari, M; Mirsalehi, M; Rezaei, M | 1 |
| Arslan, S; Ekin, N; İbiloğlu, İ; Kaplan, İ; Şenateş, E; Uçmak, F | 1 |
| Almeida, RM; Alves, EO; Amorin, R; Barros, AD; Bocca, AL; Borin, MF; Cavalcanti, FF; Jerônimo, MS; MoritaI, VE; Nóbrega, YK; Souza, NL | 1 |
| Castania, V; Defino, HL; Del Bel, E; Ferreira, FR; Ferreira, NR; Issy, AC; Resende, FF; Silveira, JW; Titze-de-Almeida, R; Titze-de-Almeida, SS | 1 |
| Arima, N; Endo, T; Ibaraki, H; Kanazawa, T; Seta, Y; Takashima, Y | 1 |
| Agulla, J; Almeida, Á; Bobo-Jiménez, V; Bolaños, JP; Castillo, J; Duarte, JJ; Gómez-Sánchez, JC; Ramos-Araque, ME; Rodríguez, C; Sobrino, T | 1 |
| Hiroaki-Sato, VA; Joca, SR; Sales, AJ | 1 |
| Anderton, RS; Chiu, LS; Knuckey, NW; Meloni, BP | 1 |
| Akdemir, F; Dundar, S; Eltas, A; Hakki, SS; Komorowski, J; Malkoc, S; Ozercan, IH; Sahin, K; Tuzcu, M; Uslu, MO | 1 |
| Bobe, G; Hall, JA; Jewell, DE; Obare, E; Panickar, KS; Yerramilli, M | 1 |
| Nader, MA; Wagih, HM | 1 |
| Cheng, L; Qiao, Z; Shen, J; Xu, C | 1 |
| Morgenstern, R; Netzhammer, N; Seidemann, T; Spies, C; Wernecke, KD | 1 |
| Chen, HW; Feng, J; Pi, LJ; Wang, J; Zhan, DQ | 1 |
| Castro Ochoa, KF; Nava, P; Schnoor, M; Shibayama, M; Silva Olivares, A; Vargas Robles, H | 1 |
| Li, L; Lim, JA; Puertollano, R; Raben, N; Shirihai, OS; Trudeau, KM | 1 |
| Bache, RJ; Chen, Y; Fassett, JT; Hu, X; Li, J; Xu, X; Zhang, P; Zhu, G | 1 |
| Booker, SA; Currie, SP; Daw, MI; Kind, PC; Luz, LL; Wyllie, DJ | 1 |
| Andreatini, R; Bortolanza, M; da Cunha, JM; Del Bel, EA; Frazão Vital, MAB; Siba, IP; Zanoveli, JM | 1 |
| Cai, Q; Everett, J; Gordon, V; Rumbaugh, K; Turner, K; Whiteley, M | 1 |
| Atabey, N; Demir, O; Demir, T; Durmus, N; Esen, A; Evcim, S; Gidener, S; Irer, B; Kahraman, E; Soner, BC; Toylu, A | 1 |
| Chen, D; Dai, B; Dai, J; Jiang, Q; Li, L; Li, Q; Song, X; Teng, H; Xu, Z; Yan, W; Yang, F; Yao, Y | 1 |
| Chernichovski, T; Filip, I; Ingbir, M; Levin-Iaina, N; Levo, Y; Reshef, R; Rozovski, U; Schwartz, D; Schwartz, IF; Shtabsky, A | 1 |
| Lechin, F; van der Dijs, B | 1 |
| Chernichovski, T; Davidovitz, A; Guzner-Gur, H; Levin-Iaina, N; Levo, Y; Schwartz, D; Schwartz, IF | 1 |
| Kostakis, A; Kostakis, M; Liarakos, N; Margaritis, E; Pantopoulou, A; Perrea, D; Poulakou, M; Yanni, AE | 1 |
| Arning, E; Bottiglieri, T; Cooke, JP; Dayal, S; Faraci, FM; Kimoto, M; Lentz, SR; Murry, DJ; Rodionov, RN | 1 |
| Bhatnagar, A; Kaiserova, K; Ramana, KV; Srivastava, SK; West, MB | 1 |
| Kim, HH; Kwiatkowski, DJ; Liao, JK; Salomone, S; Sawada, N | 1 |
| Alm, P; Efendic, S; Guenifi, A; Henningsson, R; Jimenez-Feltström, J; Lundquist, I; Mosén, H; Ostenson, CG; Salehi, A | 1 |
| Haghjooyjavanmard, S; Mahmoodi, F; Monajemi, AR; Nematbakhsh, M | 1 |
| Korda, M; Kubant, R; Malinski, T; Patton, S | 1 |
| Argoud, K; Bihoreau, MT; Collins, SC; Gauguier, D; Kaisaki, PJ; Ktorza, A; Ria, M; Rorsman, P; Wallace, KJ; Wallis, RH; Wilder, SP | 1 |
| Dehpour, AR; Gholipour, T; Jabbarzadeh, A; Nezami, BG; Rasouli, A; Riazi, K; Sharifzadeh, M | 1 |
| Kuphal, KE; Pedrazzini, T; Solway, B; Taylor, BK | 1 |
| Haghjooy Javanmard, S; Monajemi, A; Nematbakhsh, M | 1 |
| Bortolatto, CF; Jesse, CR; Nogueira, CW; Rocha, JB; Savegnago, L | 1 |
| Damiani, E; Drögemüller, C; Drögemüller, M; Gentile, A; Leeb, T; Mascarello, F; Rossi, M; Sacchetto, R; Testoni, S | 1 |
| Ferentc, M; Gzregotsky, M; Urbanovych, A; Yaschenko, A; Zayachkivska, O | 1 |
| Byku, M; Macarthur, H; Westfall, TC | 1 |
| Chen, S; Gong, J; Lao, XJ; Zhang, SJ | 1 |
| Ercan, F; Onol, FF; Ozgür, A; Tarcan, T | 1 |
| Chen, W; Liang, Z; Liu, H; Qu, X; Song, Y; Xia, W | 1 |
| Fukami, K; Hayashida, A; Kaida, Y; Kato, S; Kimoto, M; Matsumoto, Y; Matsuoka, H; Okuda, S; Shibata, R; Ueda, S; Yamagishi, S | 1 |
| Bratt, JM; Franzi, LM; Kenyon, NJ; Last, JA; Last, MS; Linderholm, AL | 1 |
| Crestani, F; Knabl, J; Rudolph, U; Zeilhofer, HU; Zeilhofer, UB | 1 |
| Acquaviva, R; Caltabiano, R; Di Cataldo, A; Di Giacomo, C; Lanteri, R; Lanzafame, S; Li Destri, G; Li Volti, G; Vanella, L | 1 |
| Bahlo, M; Cain, SM; David, LS; Foote, SJ; Garcia, E; Kyi, M; Ng, C; O'Brien, TJ; Powell, KL; Reid, CA; Sirdesai, S; Snutch, TP; Tyson, JR | 1 |
| Babetto, E; Beirowski, B; Coleman, MP; Conforti, L; Gilley, J; Janeckova, L; Magni, G; Mazzola, F; Ribchester, RR | 1 |
| Azam, MA; Durante, W; Ensenat, D; Kannan, S; Keswani, AN; Liu, XM; Peyton, KJ; Tulis, DA; Wang, H | 1 |
| Adame, A; Crews, L; Gage, FH; Hersh, LB; Mante, M; Marr, RA; Masliah, E; Potkar, R; Rockenstein, E; Rose, JB; Spencer, B | 1 |
| Bahremand, A; Dehpour, AR; Ghasemi, M; Nasrabady, SE; Shafaroodi, H | 1 |
| Gryglewski, R; Hassan, M; Heeba, G; Khalifa, M; Malinski, T; Moselhy, ME | 1 |
| Ayer, R; Chen, W; Jadhav, V; Sugawara, T; Suzuki, H; Zhang, JH | 1 |
| Derrick, M; Igarashi, J; Ji, H; Li, H; Martásek, P; Poulos, TL; Roman, LJ; Silverman, RB; Tan, S; Vásquez-Vivar, J | 1 |
| Fujisaki, Y; Horii, Y; Nagai, K; Shen, J | 1 |
| Bos, IS; Bossenga, BE; Maarsingh, H; Meurs, H; Volders, HH; Zaagsma, J | 1 |
| Bonorino, C; Detanico, T; Guth, A; Smith, D; Tung, KS; Wysocki, LJ | 1 |
| Bjelakovic, G; Djindjic, B; Kocic, G; Nikolic, J; Pavlovic, D; Pavlovic, V; Sokolovic, D; Stojanovic, I | 1 |
| Chan, CH; Pearce, DA; Ramirez-Montealegre, D | 1 |
| Boontje, NM; de Crom, R; de Waard, MC; Dekkers, DH; Duncker, DJ; Kuster, DW; Lamers, JM; van der Velden, J; van Haperen, R | 1 |
| Aoki, M; Itoyama, Y; Kobayashi, M; Nagai, M; Sasaki, S | 1 |
| Fredstrom, SB; Gallaher, DD; Jessurun, J | 1 |
| Fujimi-Hayashida, A; Fukami, K; Kaida, Y; Koike, K; Matsumoto, Y; Okuda, S; Tanaka, H; Ueda, S; Yamagishi, S | 1 |
| Butler, AE; Butler, PC; Cox, HI; Dry, S; Galasso, R; Gurlo, T; Matveyenko, AV; Moshtaghian, A | 1 |
| Catterall, WA; Dutt, K; Escayg, A; Goldin, AL; Hunter, J; Mantegazza, M; Papale, L; Rusconi, R; Shankar, A; Tang, B; Tufik, S; Yu, FH | 1 |
| Jadhav, A; Ndisang, JF | 3 |
| Robertus, AI; Tiurenkov, IN; Voronkov, AV | 1 |
| Kehl, F; Lange, M; Lotz, C; Redel, A; Roewer, N; Smul, TM; Stumpner, J | 1 |
| Banday, AA; Lokhandwala, MF | 1 |
| Gray, GA; Leiper, JM; Malaki, M; Miller, AA; Patrizio, M; Sherry, L; Vallance, P; Wallace, AF | 1 |
| Kida, Y; Marumo, K; Saito, M; Shinohara, A; Soshi, S; Ushiku, C | 1 |
| Morris, SM | 1 |
| Carletti, F; D'Agostino, S; Ferraro, G; Lonobile, G; Rizzo, V; Sardo, P | 1 |
| Cerski, CT; Giovanardi, RO; Kalil, AN; Rhoden, EL; Salvador, M | 1 |
| Andrews, KL; Chin-Dusting, JP; Du, XJ; Head, GA; Huynh, NN; Khong, SM; Kiriazis, H; Lambert, G; Mayorov, DN; Murphy, AJ; Xu, Q | 1 |
| Amaral, JF; Araújo, FL; Barbosa-Filho, JM; de Sousa, FC; Gutierrez, SJ; Leite, CP; Melo, CT; Moura, BA; Rocha, NF; Vasconcelos, SM; Viana, GS | 1 |
| Fukuda, S; Ishii, Y; Matsui, K; Matsushita, M; Miyajima, K; Nishizawa, E; Oda, T; Ohta, T; Sano, R; Sasase, T; Ueda, N; Yamamoto, H | 1 |
| Böger, R; Lüneburg, N; Maas, R | 1 |
| Chen, C; Claes, LR; De Jonghe, P; Dondeti, RS; Gray, CB; Isom, LL; Lopez-Santiago, LF; Miyazaki, H; Nukina, N; O'Malley, HA; Oyama, F; Patino, GA; Slat, EA | 1 |
| Barbaros, B; Filiz, B; Gonca, O; Halil, Y; Nihal, S; Nurten, T; Ozgür, A | 1 |
| Jiang, H; Li, Y; Lin, G; Zeng, H; Zhao, A | 1 |
| Fan, J; Guo, G; Li, T; Li, X; Ma, L; Meng, Q; Xie, Y; Xiu, Y | 1 |
| Durand, J; Gueritaud, JP; Pambo-Pambo, A | 1 |
| Alavi, H; Gorji, A; Hosseini, M; Sadeghnia, HR; Salehabadi, S | 1 |
| Delgado, JM; Jiménez-Capdeville, ME; Ortiz-Pérez, D; Ríos, R; Santoyo, ME; Zarazúa, S | 1 |
| Baylis, C; Chen, GF | 1 |
| Hao, ML; Jia, XG; Shi, L; Tang, LL; Wang, WT; Zhang, YH | 1 |
| Arnaout, O; Bendok, BR | 1 |
| Dehpour, AR; Ghaffarpour, M; Ghasemi, M; Gholipour, T; Riazi, K | 1 |
| Garg, R; Gaur, V; Kumar, A; Kumar, P | 1 |
| Agar, E; Ayyildiz, M; Yildirim, M | 2 |
| Fylymonenko, VP; Kaliman, PA; Nikitchenko, IV | 1 |
| Grisotti, G; Roos, RP; Wang, L | 1 |
| Cai, JM; Chen, H; Fan, LY; Li, Y; Liu, WW; Ruan, CP; Su, N; Sun, Q; Sun, XJ; Sun, YP; Wang, Q; Xiang, HG; Xu, XY; Yan, RL | 1 |
| Cheng, S; Shi, JD; Song, MM; Yan, WM; Yang, B; Zhao, Y | 1 |
| Bruins, MJ; Deutz, NE; Luiking, YC; Poeze, M | 1 |
| Agrawal, A; Ahmad, T; Dinda, AK; Ghosh, B; Joseph, DA; Leishangthem, GD; Mabalirajan, U | 1 |
| Lee, CH; Lo, HC; Wang, YH; Wu, SC | 1 |
| Chen, CC; Hsieh, CS; Huang, LT; Lee, CT; Sheen, JM; Tain, YL | 1 |
| André, C; Bagnost, T; Berthelot, A; da Silva, RF; Demougeot, C; Guillaume, Y; Houdayer, C; Ma, L; Rezakhaniha, R; Stergiopulos, N | 1 |
| Bahremand, A; Dehpour, AR; Hedayat, T; Nasrabady, SE; Payandemehr, B; Rahimian, R; Ziai, P | 1 |
| Fujikura, Y; Hamanishi, S; Ishiyama, H; Ogino, K; Shibamori, M; Takahashi, N; Takemoto, K; Takigawa, T; Wang, DH | 1 |
| Khanduja, KL; Malhotra, S; Pandhi, P; Sidhu, S; Vaiphei, K | 1 |
| Chen, WM; Deng, J; Huang, XN; Wang, YW; Wu, Q | 1 |
| Mangioris, G; Mendrinos, E; Papadopoulou, DN; Petropoulos, IK; Pournaras, CJ | 1 |
| Bahremand, A; Dehpour, AR; Ghasemi, A; Ghasemi, M; Hedayat, T; Khodadad, TK; Payandemehr, B; Rahimian, R; Ziai, P | 1 |
| Aker, S; Boengler, K; Canton, M; Deindl, E; Di Lisa, F; Heusch, G; Heusch, P; Klein, K; Konietzka, I; Menazza, S; Rassaf, T; Schulz, R; Sewell, A; van de Sand, A | 1 |
| Li, L; Liu, YZ; Luo, XJ; Peng, J; Tan, N; Xiang, DX; Yuan, Q; Zhang, YS | 1 |
| Agrawal, A; Ahmad, T; Aich, J; Ghosh, B; Mabalirajan, U; Makhija, L; Sharma, A | 1 |
| Becker, M; Bossi, L; Cha, HJ; de la Porte, S; Escolar, DM; Farajian, V; Francia, D; Gernapudi, R; Gordish-Dressman, H; Guerron, AD; Hoffman, EP; Nagaraju, K; Pandey, GS; Partridge, T; Pistilli, E; Rawat, R; Sali, A; Spurney, CF; Zerr, P | 1 |
| Chiaramonte, MG; Ellies, LG; Niese, KA; Rothenberg, ME; Zimmermann, N | 1 |
| Arjmand, M; Farahmand, M; Ghasemi, F; Hajihosseini, R; Nahrevanian, H | 1 |
| Asai, Y; Inoue, T; Iwata, M; Suzuki, S; Takagi, K | 1 |
| Asim, M; Barry, DP; Casero, RA; Chaturvedi, R; Cheng, Y; Closs, EI; de Sablet, T; Gobert, AP; Hoge, S; Lewis, ND; Piazuelo, MB; Sarvaria, AR; Singh, K; Wilson, KT | 1 |
| Atomi, Y; Hatta, H; Lee, S; Ohsako, M; Sakurai, T; Saura, R | 1 |
| Gaur, V; Kumar, A | 1 |
| Abdel Baky, NA; Fatani, AJ; Sayed-Ahmed, MM; Yaqub, H; Zaidi, ZF | 1 |
| Chan, CC; Chan, JF; Chan, KH; Chen, H; Jin, DY; Leung, VH; Poon, VK; To, KK; Woo, PC; Yuen, KY; Zhang, AJ; Zhang, K; Zheng, B; Zhou, J | 1 |
| Alves, CC; Arias, V; Brentani, MM; da Silva, LF; Giorgi, R; Logullo, AF; Mauad, T; Torrinhas, RS; Waitzberg, DL | 1 |
| Castañeda-Hernández, G; Esquivel-Aguilar, A; Franco-Bourland, RE; Guízar-Sahagún, G; Madrazo, I; Martínez-Cruz, A | 1 |
| Craig, T; Durante, W; Johnson, FK; Johnson, RA; Myers, JG; Peyton, KJ; Stewart, RM | 1 |
| Aubin, I; Barnhart, KF; Benavides, F; Brandon, JL; Conti, CJ; DiGiovanni, J; Gimenez-Conti, I; Giulivi, C; Guénet, JL; Jaubert, J; Kusewitt, DF; Otto, NW; Perez, CJ; Quintanilla, VC; Ross-Inta, CM | 1 |
| Aviszus, K; Detanico, T; Guo, W; Heiser, RA; Smith, D; Wysocki, LJ | 1 |
| Aschner, JL; Eaton, F; Magarik, J; Rey-Parra, GJ; Summar, M; Thébaud, B; Vadivel, A; Zeng, H | 1 |
| Behrend, K; Cerny, V; Fuchs, C; Hung, O; Ladwig, E; Lehmann, C; Murphy, M; Pavlovic, D; Whynot, S; Zhou, J | 1 |
| Abe, T; Hishinuma, T; Saigusa, D; Shiba, K; Suzuki, N; Takahashi, M; Tanaka, S; Tomioka, Y | 1 |
| Agrawal, A; Ahmad, T; Dinda, AK; Ghosh, B; Leishangthem, GD; Mabalirajan, U | 1 |
| Deng, SX; Du, YQ; Gong, YF; Gu, JJ; Kong, XY; Li, L; Li, ZS; Liu, JQ; Man, XH; Wang, GK; Xiao, LN; Zheng, YZ; Zhu, JQ | 1 |
| Black, SM; Catravas, JD; Fineman, JR; Fratz, S; Haag, S; Hess, J; Hou, Y; Kumar, S; Naumann, S; Patterson, C; Rafikov, R; Rehmani, I; Reiser, J; Schreiber, C; Sharma, S; Smith, A; Sun, X; Tian, J | 1 |
| Asghari-Roodsari, A; Dehpour, AR; Javadi-Paydar, M; Khodadad, TK; Lesani, A; Norouzi, A; Shirkhodaei, M | 1 |
| Buford, MC; Holian, A; Klein, E; Weigel, J; Wells, SM | 1 |
| Bode-Böger, SM; Bukowska, A; Dobrev, D; Goette, A; Hammwöhner, M; Lendeckel, U; Martens-Lobenhoffer, J; Medunjanin, S; Ravens, U; Scalera, F; Weinert, S | 1 |
| Horowitz, JD; Kelly, DJ; Kennedy, JA; Ngo, DT; Qi, W; Smith, MD; Stafford, I; Sverdlov, AL; Weedon, H; Wuttke, RD; Zhang, Y | 1 |
| Kato, S; Kida, Y; Kuroda, T; Marumo, K; Saito, M; Takao-Kawabata, R; Ushiku, C | 1 |
| Aizawa, N; Igawa, Y; Nishizawa, O; Wyndaele, JJ | 1 |
| Bersten, AD; Dixon, DL; Elder, AS; Saccone, GT | 1 |
| Bratt, JM; Kenyon, NJ; Last, JA; Rabowsky, M; Zeki, AA | 1 |
| Carlström, M; Hezel, M; Larsson, E; Lundberg, JO; Persson, AE; Scheffer, PG; Teerlink, T; Weitzberg, E | 1 |
| Chernichovski, T; Engel, A; Grupper, A; Hillel, O; Schwartz, D; Schwartz, IF | 1 |
| Collin, B; Cottin, Y; Duvillard, L; Goirand, F; Guilland, JC; Korandji, C; Lauzier, B; Moreau, D; Rochette, L; Sicard, P; Vergely, C; Zeller, M | 1 |
| Akhtar, E; Butcher, EC; Collins, SD; Habtezion, A; Kwan, R; Omary, MB; Stevenson, DK; Wanaski, SP; Wong, RJ | 1 |
| Cheng, L; Guo, C; Han, W; He, M; Hu, G; Huang, L; Shen, J; Wang, F; Wang, X; Wu, M; Xiang, D; Xu, X; Yang, L; Yu, Y; Zhu, S | 1 |
| Dehpour, AR; Hajimirzabeigi, A; Khalilzadeh, O; Maleki, F; Zandieh, A; Zandieh, B | 1 |
| Chen, M; Huo, Y; Li, J; Lou, L; Pan, C; Singh, G; Wang, S; Wu, A; Zhang, D; Zhao, M | 1 |
| Cerrato, R; Grönros, J; Jung, C; Lundberg, JO; Ostenson, CG; Pernow, J | 1 |
| Dehpour, AR; Fakhraei, N; Javadi-Paydar, M; Mirazi, N; Norouzi, A; Rayatnia, F; Zakeri, M | 1 |
| Kostić, S; Puljak, L; Sapunar, D; Vukojević, K | 1 |
| Cheung, CW; Irwin, MG; Liu, YT; Lv, H; Song, JG; Tao, KM; Wong, GT; Wu, FX; Yang, LQ; Yu, WF | 1 |
| Causey, CP; Chumanevich, AA; Chumanevich, AP; Davis, T; Hofseth, LJ; Jones, JE; Knuckley, BA; Matesic, LE; Poudyal, D; Thompson, PR | 1 |
| Ellrich, J; Isaak, A | 1 |
| Bonilla, I; Cardounel, AJ; Carnes, CA; Elton, TS; Györke, S; Khan, M; Kuppusamy, P; Li, C; Nishijima, Y; Sridhar, A; Terentyev, D; Terentyeva, R; Velayutham, M; Zweier, JL | 1 |
| Chang, YJ; Hsiao, CC; Hung, CY; Lee, CH; Lo, HC | 1 |
| Akgul, EO; Aydin, I; Bilgi, C; Cakir, E; Cayci, T; Ceyhan, TS; Erbil, KM; Kurt, YG; Onguru, O; Yaman, H; Yasar, M | 1 |
| Behrens, A; Davis, H; Lewis, A; Spencer-Dene, B; Stamp, G; Tateossian, H; Tomlinson, I | 1 |
| Bruins, MJ; Deutz, NE; Kessels, F; Lamers, WH; Luiking, YC; Poeze, M | 1 |
| Nelson, RJ; Weber, MD; Workman, JL | 1 |
| Aizawa, K; Ishizuka, N; Iwabuchi, S; Kitamura, H; Moriguchi, Y; Nishimura, T; Serizawa, K; Tashiro, Y; Yogo, K; Yorozu, K | 1 |
| Braun, M; Celec, P; Halčák, L; Hodosy, J; Holzerová, J; Janega, P; Jáni, P; Kalousová, M; Kúdela, M; Murín, J; Parrák, V; Pecháň, I; Šebeková, K; Zima, T | 1 |
| Appleton, I; Clarkson, AN; Nair, SM; Rahman, RM; Sammut, IA; Sutherland, BA; Taurin, S | 1 |
| Melo, AC; Nesi, RT; Pimenta, WA; Porto, LC; Rueff-Barroso, CR; Silva, MA; Valença, SS | 1 |
| Atkinson, MA; Becker, DJ; Haller, MJ; Ize-Ludlow, D; Lightfoot, YL; Mathews, CE; Parker, M; Schatz, D; Wasserfall, C; Xue, S | 1 |
| Akhtar, MN; Akira, A; Israf, DA; Khalid, MH; Lajis, N; Mohamad, AS; Perimal, EK; Sulaiman, MR | 1 |
| Baydemir, C; Dogan, AE; Erol, K; Kilic, FS | 1 |
| Pi, M; Quarles, LD | 1 |
| Andreatini, R; Chioca, LR; Correia, D; Pereira, M; Pizzolatti, MG; Santos, AR; Siba, IP; Vital, MA | 1 |
| Hänggi, D; Ogawa, T; Steiger, HJ | 1 |
| Baumbach, G; Bengrine, A; Bode-Boeger, SM; Bugnicourt, JM; Chillon, JM; Da Silveira, C; Godefroy, O; Kielstein, JT; Massy, ZA; Sevestre, H | 1 |
| Brouwers, N; Funamoto, S; Ihara, Y; Iwata, N; Matsuba, Y; Mihira, N; Nilsson, P; Nishimura, M; Saido, TC; Saito, T; Sleegers, K; Suemoto, T; Takano, J; Van Broeckhoven, C; Yamada, K | 1 |
| Galvano, F; Li Volti, G; Mangiameli, A; Salamone, F; Salomone, S; Siarkos, I; Sorrenti, V; Urso, V | 1 |
| Dal-Cim, T; Maraschin, M; Rodrigues, AL; Tasca, CI; Zeni, AL; Zomkowski, AD | 1 |
| Acehan, D; Barilla, R; Bedrosian, AS; Cieza-Rubio, NE; Cohen, SM; Connolly, MK; Frey, AB; Hackman, M; Henning, JR; Ibrahim, J; Malhotra, A; Medina-Zea, MV; Miller, G; Nguyen, AH; Pachter, HL; Rehman, A | 1 |
| Balen, Gde O; Budni, J; Fernandes, SC; Freitas, AE; Moretti, M; Rodrigues, AL | 1 |
| Bastianetto, S; Benoit, CE; Dumont, Y; Flores, G; Fournier, A; Morales-Medina, JC; Quirion, R | 1 |
| Chabeauti, PY; Chalon, S; Decressac, M; Frangeul, L; Gaillard, A; Herzog, H; Jaber, M; Pain, S; Thiriet, N; Vergote, J | 1 |
| Skliarov, OIa; Zhuroms'kyĭ, VS | 1 |
| Garcia, T; González, AM; Molero, X; Rickmann, M; Samper, E; Vaquero, EC | 1 |
| Arnaud, P; Chaumeil, JC; Curis, E; Cynober, L; Elwafi, F; Moinard, C; Neveux, N; Zerrouk, N | 1 |
| Collie, ND; Fleete, MS; Jing, Y; Knox, LT; Liu, P; Zhang, H | 1 |
| Bender, M; Edwards, L; Garzon-Muvdi, T; Momin, EN; Pradilla, G; Ruzevick, JJ; Tamargo, RJ; Thompson, RC | 1 |
| Callaerts-Vegh, Z; Carmeliet, P; Collen, D; D'Hooge, R; Dewerchin, M; Lupu, F; Moons, L; Nuyens, D; Silasi-Mansat, R; Souffreau, J; Van Nuffelen, A; Wallays, G | 1 |
| Gupta, A; Kalonia, H; Kumar, A; Kumar, P; Meena, S | 1 |
| Bharrhan, S; Kaur, IP; Rishi, P; Singh, G | 1 |
| Cohen, H; Kaplan, Z; Kozlovsky, N; Liu, T; Mathé, AA; Zohar, J | 1 |
| Büchler, MW; Gebhard, MM; Hackert, T; Hartwig, W; Kaiser, H; Klar, E; Schmidt, J; Werner, J | 1 |
| Dugas, TR; Foley, JD; Hebert, VY; Kleinedler, JJ; Orchard, EA; Rogers, LK | 1 |
| Asgeirsson, T; Cavey, GS; Dujovny, N; Luchtefeld, M; Mascarenas, C; Nunoo, R; Senagore, A; Zhang, S | 1 |
| Grant, MB; Li Calzi, S; Li, N; Liu, X; Ma, L; Neu, J; Shaw, L | 1 |
| Berrocoso, E; Leza, JC; Mico, JA; Ortega-Álvaro, A; Rey-Brea, R | 1 |
| Goshima, H; Mizutani, N; Nabe, T; Yoshino, S | 1 |
| Aschner, JL; Bertin, TK; Black, JO; Bryan, NS; Campeau, PM; Chen, Y; Erez, A; Garg, HK; Harrison, DG; Lee, B; Li, L; Marini, JC; Mian, A; Mitch, WE; Nagamani, SC; O'Brien, WE; Premkumar, MH; Reddy, AK; Shchelochkov, OA; Summar, M; Tang, Y; Zeng, H | 1 |
| Beloor, J; Choi, CS; Jackson, A; Kim, SH; Kim, SW; Kumar, P; Lee, KY; Lee, SK; Nam, HY; Park, M | 1 |
| Burkhardt, H; Dobritzsch, D; Holmdahl, R; Lindh, I; Nandakumar, KS; Schneider, G; Uysal, H | 1 |
| Andersen, JT; Bjarnarson, SP; de Haas, M; Gerritsen, J; Jonsdottir, I; Kleijer, M; Sandlie, I; Stapleton, NM; Stemerding, AM; van der Schoot, CE; Verheul, RC; Vidarsson, G; Zhao, Y | 1 |
| Wilcox, CS | 1 |
| Bustos, PS; Cabrera, JL; Chiabrando, GA; Ortega, MG; Pierosan, L; Santos, AR; Saragusti, AC | 1 |
| Belenichev, IF; Sokolik, EP | 1 |
| Ebinuma, H; Hibi, T; Hozawa, S; Kanai, T; Miyata, N; Nakamura, Y; Nakano, M; Ono, Y; Saeki, K; Sujino, T; Takaishi, H; Takeda, K; Yamagishi, Y; Yoshimura, A | 1 |
| Choi, JI; Kim, WM; Kim, YO; Lee, HG; Yoon, MH | 1 |
| Kokare, DM; Nakhate, KT; Rangani, RJ; Subhedar, NK; Upadhya, MA | 1 |
| Anegawa, T; Aoki, H; Aoki, Y; Imaizumi, T; Kai, H; Kajimoto, H; Okuda, S; Ueda, S; Yasuoka, S | 1 |
| de Cabo, C; Escribano, J; Llorens, S; López, DE; Muñoz, LJ; Nava, E; Pardal-Fernández, JM; Prieto-Martín, AI | 1 |
| Barten-van Rijbroek, AD; Bijlsma, JW; DeGroot, J; Lafeber, FP; Mastbergen, SC; Vos, PA; Zuurmond, AM | 1 |
| Cortes, SF; Duarte, ID; Galdino, GS; Perez, AC; Resende, LC; Romero, TR; Silva, GC | 1 |
| Dalton, RN; Davies, NA; Deutz, NE; Jalan, R; Mookerjee, RP; Revhaug, A; Rose, CF; Sen, S; Sharma, V; Ten Have, GA; Turner, C; van-Eijk, HM; Ytrebo, L | 1 |
| Khazaei, M; Mobarakeh, JI; Rahimi, AA; Razavi, MR | 1 |
| Albertin, G; Artusi, C; Bordigato, MA; Chiandetti, L; De Caro, R; Dedja, A; Fassina, A; Filippone, M; Grisafi, D; Guzzardo, V; Macchi, V; Masola, V; Milan, A; Onisto, M; Oselladore, B; Porzionato, A; Salmaso, R; Tassone, E; Zaninotto, M; Zaramella, P | 1 |
| Probe, R; Sampson, W; Souder, N; Stahl, D; Tharakan, B; Ward, R | 1 |
| Billecke, S; Chen, AF; Craig, T; D'Alecy, LG; Haywood, JR; Hinojosa-Laborde, C; Northcott, CA; Patel, KP | 1 |
| Kimura, K | 1 |
| Azuma, T; Hayakumo, T; Izumi, Y; Kobayashi, T; Kutsumi, H; Nishiumi, S; Sakai, A; Shiomi, Y; Yoshida, M | 1 |
| Gao, J; Han, W; Lu, H; Qian, L; Shen, J; Shen, Z; Wan, R; Wang, X | 1 |
| Cvetkovic, T; Ljubisavljevic, S; Pavlovic, D; Pavlovic, R; Sokolovic, D; Stevanovic, I; Stojanovic, I | 1 |
| Khan, MW; Khan, S; Khan, SA; Naqshbandi, A; Priyamvada, S; Yusufi, AN | 1 |
| Brunetti-Pierri, N; Bryan, NS; Campeau, PM; Caudle, S; Chen, Y; Erez, A; Feig, DI; Guse, K; Harrison, D; Lee, B; Li, L; Marini, JC; Nagamani, SC; Palmer, D; Premkumar, MH; Reddy, AK; Salviati, L; Shchelochkov, OA; Slesnick, TC; Sun, Q; Tang, Y | 1 |
| Hashizume, K; Ichikawa, K; Kikuchi, N; Matsuzawa, A; Miyamoto, T; Nagano, R; Nakamura, T; Ohnota, H; Ozawa, T; Shiohara, H | 1 |
| Li, X; Liu, C; Sun, D; Wang, Y; Xiao, A; Zhou, X | 1 |
| Aramburo, A; Black, SM; Fineman, JR; Kalkan, G; Kallarackal, S; Kumar, S; Rafikov, R; Rehmani, I; Sharma, S; Sun, X; Tian, J | 1 |
| Baier, H; Ingraham, HA; Meijsing, SH; Muto, A; Schaaf, MJ; Schoonheim, PJ; Strasser, D; Yamamoto, KR; Ziv, L | 1 |
| Chen, B; Cheng, Q; Friedman, B; Lei, IF; Lyden, PD; Olson, ES; Pereira, B; Tsien, RY; Whitney, MA; Winkle, JA; Zhao, L | 1 |
| Araie, M; Ishii, K; Mayama, C; Ota, T; Tomidokoro, A | 1 |
| Choi, YH; Noh, JS; Song, YO | 1 |
| Bettio, LE; Budni, J; Colla, AR; Cunha, MP; Oliveira, Á; Pazini, FL; Rodrigues, AL | 1 |
| Ando, R; Fukami, K; Iwatani, R; Kaida, Y; Nakayama, Y; Okuda, S; Ueda, S; Yamagishi, S | 1 |
| Chen, HX; Chen, X; Deng, LH; Diao, TJ; Gao, BC; Liang, Y; Wang, QH; Ye, Y; Yuan, WS; Zhao, XD | 1 |
| Dillmann, WH; Kucukoglu, O; Lunova, M; Schwarz, C; Strnad, P; Wagner, M; Zizer, E | 1 |
| Austin, EV; Hagemann, TL; Jacka, EM; Johnson, DA; Johnson, JA; LaPash Daniels, CM; Messing, A; Rockney, DE | 1 |
| Gong, SG | 1 |
| Backos, DS; Patel, M; Reigan, P; Ryan, K | 1 |
| Fujikura, Y; Kubo, M; Ogino, K; Takahashi, H; Zhang, R; Zou, Y | 1 |
| Beamer, E; Otahal, J; Sills, GJ; Thippeswamy, T | 1 |
| Uomo, G | 1 |
| Atli, O; Demirel-Yilmaz, E; Ilgin, S; Sirmagul, B; Usanmaz, SE | 1 |
| Cruz-González, I; López-Jiménez, R; Perez-Rivera, A; Yan, BP | 1 |
| Bertagnolli, M; Cloutier, A; Comte, B; Germain, N; Huyard, F; Nuyt, AM; Yzydorczyk, C | 1 |
| Caplin, B; Delahaye, M; Dowsett, L; Leiper, J; Salama, A; Slaviero, A; Tomlinson, J; Wang, Z; Wheeler, DC | 1 |
| Bento, DR; Caricati-Neto, A; Chihara, RT; Fagundes, DJ; Fernandes, DT; Gomez, JS; Miranda-Ferreira, R; Monteiro, HP; Oliveira-Junior, IS; Rodrigues, LW; Simões, MJ; Taha, MO; Taha, NS | 1 |
| Cai, QP; Chen, J; Chen, XY; Fu, HB; Shen, PJ; Wang, CM; Yan, RL; Yang, DJ | 1 |
| Hanawa, T; Hori, A; Ito, N; Nagai, T; Oikawa, T; Yabe, T; Yamada, H | 1 |
| Algül, H; Diakopoulos, KN; Dlubatz, K; Einwächter, H; Halangk, W; Lesina, M; Liang, S; Neuhöfer, P; Schmid, RM; Schulz, HU; Schwerdtfeger, C; Treiber, M; Wartmann, T; Witt, H; Wörmann, S; Zhang, H | 1 |
| Chen, X; Cui, L; Guan, T; Kong, J; Li, C; Li, XM; Shang, H; Zhang, X | 1 |
| Calvert, TJ; Chen, B; Chicoine, LG; Jin, Y; Liu, Y; Nelin, LD | 1 |
| Aydemir, G; Aydinoz, S; Babacan, O; Canpolat, FE; Çekmez, F; Cetinkaya, M; Fidancı, K; Karaoğlu, A; Purtuloğlu, T; Süleymanoglu, S; Tunc, T | 1 |
| Fabry, ME; Kaul, DK; Suzuka, SM; Zhang, X | 1 |
| Chen, GY; Chen, WW; Tang, WF; Wan, MH; Xiang, J; Yu, Q; Zhao, XL | 1 |
| Cavalcante Melo, FH; Citó, Mdo C; de Sousa, DP; de Sousa, FC; de Vasconcelos, SM; Fernandes, ML; Rios, ER; Rocha, NF | 1 |
| Ali, SA; Aly, HF; Faddah, LM; Zaidi, ZF | 1 |
| Aggarwal, S; Black, SM; Burns, T; Dasarathy, S; Fineman, JR; Fratz, S; Kumar, S; Lu, Q; Radman, M; Rafikov, R; Rafikova, O; Schreiber, C; Sharma, S; Sun, X; Wright, J | 1 |
| Bai, Y; Dillon, LM; Feltri, ML; Kamholz, J; Katona, I; Kirschner, D; Patzkó, A; Saporta, MA; Sarkar, FH; Shy, ME; Vizzuso, D; Wang, S; Wrabetz, L; Wu, X | 1 |
| Almeida, FR; Brandão, MS; Chaves, MH; Ferreira, EL; Lima, DF; Oliveira, JP; Pereira, SS | 1 |
| Chen, CC; Huang, LT; Kao, YH; Lee, CT; Sheen, JM; Tain, YL; Yu, HR | 1 |
| Cortina, B; Lluch, P; Lluch, S; Mauricio, MD; Medina, P; Segarra, G; Serna, E | 1 |
| Cavalcante Melo, FH; de Carvalho Lima, CN; de França Fonteles, MM; Freire Vasconcelos, L; Leite Dias, M; Moura Rocha, NF; Rodrigues Carvalho, AM; Soares Lopes, K; Vasconcelos Rios, ER | 1 |
| Brown, RD; Carlström, M; Hezel, M; Larsson, E; Lundberg, JO; Persson, AE; Scheffer, PG; Teerlink, T; Yang, T | 1 |
| Attar, A; Egemen, N; Sargon, MF; Tuna, H; Yüceer, N | 1 |
| Balogh, N; Gaál, T; Krausz, F; Lévai, P; Ribiczeyné, PS; Vajdovich, P | 1 |
| Adams, M; Chatterjee, K; Kindblom, JM; Malin, S; Nordström, K; Ohlsson, C; Pettersson, S; Rajanayagam, O; Rozell, B; Thorén, P; Tinnikov, A; Vennström, B | 1 |
| Dokucu, AI; Oztürk, H; Sari, I; Yağmur, Y | 1 |
| Hiraoka, Y; Kishimoto, C; Ochiai, H; Takada, H | 1 |
| Carvajal, C; Dumont, Y; Gardell, L; Lai, J; Ossipov, MH; Porreca, F; Quirion, R; Zhang, ET | 1 |
| Bahrami, S; Costantino, G; Duvigneau, JC; Gemeiner, M; Kozlov, AV; Nohl, H; Redl, H; Sobhian, B | 1 |
| Bing, W; Chaoshu, T; Jian, L; Jianguang, Q; Junbao, D | 1 |
| Liu, B; Liu, J; Liu, X; Tang, C; Wang, H; Xie, P | 1 |
| Hoff, JT; Hua, Y; Keep, RF; Kitaoka, T; Xi, G | 1 |
| Gotoh, T; Hirata, A; Koga, T; Koshiyama, Y; Mori, M; Negi, A; Tanihara, H; Yonemura, N | 1 |
| Kinoshita, M; Matsumori, A; Miyamoto, T; Ohashi, N; Sasayama, S | 1 |
| Blum, M; Chernichovsky, T; Gnessin, E; Iaina, A; Schwartz, D; Schwartz, IF; Wollman, Y | 1 |
| Alfieri, R; Andreucci, VE; Cesaro, A; Cianciaruso, B; Fuiano, G; Pisani, A; Sabbatini, M; Uccello, F | 1 |
| Astern, J; Chen, J; Huang, PL; Ichinose, H; Kuhlencordt, P; Urano, F | 1 |
| Reade, MC; Young, JD | 1 |
| Craigen, WJ; Davis, EC; Pan, Y; Reid Sutton, V | 1 |
| Fedoruk, OS; Hozhenko, AI; Pohorila, IV | 1 |
| Albrecht, EW; Smit-van Oosten, A; Stegeman, CA; van Goor, H | 1 |
| Iadecola, C; Ross, ME; Zhao, X | 1 |
| Marik, PE | 1 |
| Bourin, M; Vasar, E; Volke, V; Wegener, G | 1 |
| Fujii, T; Ishiwata, T; Kawahara, K; Lu, YP; Naito, Z; Sugisaki, Y; Teduka, K | 1 |
| Kato, H; Kimura, S; Nakagawa, K; Nakagawa, M; Tsuji, H; Ukimura, N; Yamada, K; Yamada, Y; Yano, S | 1 |
| Kamiyama, Y; Kitade, H; Kwon, AH; Okumura, T; Satoi, S; Tu, W; Zhang, Z | 1 |
| Askew, DS; Fortwendel, JR; Oliver, BG; Panepinto, JC; Rhodes, JC; Smith, DL | 1 |
| Cartier, R; Demers, P; Elkouri, S; Sirois, MG | 1 |
| Inagi, R; Ishikawa, N; Koike, H; Kurokawa, K; Miyata, T; Mizuno, M; Nangaku, M; Sada, T; Ueda, Y; van Ypersele de Strihou, C; Yuzawa, H | 1 |
| Bhardwaj, A; Goyagi, T; Hurn, PD; Kirsch, JR; Koehler, RC; Toung, TJ; Traystman, RJ | 1 |
| Berkem, R; Besler, HT; Erdogan, S; Koc, M; Korkmaz, A; Ozalp, N; Ozmen, MM; Zulfikaroglu, B; Zulfikaroglu, E | 1 |
| Cavicchi, M; Lamarque, D; Whittle, BJ | 1 |
| Saito, T | 1 |
| Foster, PS; Hamid, Q; King, NE; Laporte, J; Mishra, A; Muntel, EE; Pegg, AA; Pope, SM; Rothenberg, ME; Witte, DP; Yang, M; Zimmermann, N | 1 |
| Batra, S; Forslid, A; Kovanen, P; Liuba, P; Paakkari, I; Pentikäinen, M; Persson, K; Pesonen, E; Sandström, S | 1 |
| Devaki, T; Ebenezar, KK; Sathish, V | 1 |
| Abreu, GR; Bissoli, NS; Cabral, AM; Gouvêa, SA; Moysés, MR; Pires, JG | 1 |
| Li, D; Lin, LN; Wang, W; Wang, WT; Xu, ZJ | 1 |
| Honda, Y; Katsuta, H; Kiryu, J; Miyahara, S; Miyamoto, K; Nishijima, K; Nonaka, A; Tsujikawa, A; Yamashiro, K | 1 |
| Cheng, S; He, SG; Li, ZH; Song, MM; Zhang, YW; Zhao, J | 1 |
| Harvala, H; Hyypiä, T; Kalimo, H; Stanway, G | 1 |
| Grosse, J; Nehls, MC; Peters, T; Popp, A; Russ, A; Schlueter, V; Sedlmeier, R; Thaete, C; Wolf, S | 1 |
| Bukan, N; Dursun, A; Engin, A; Kurukahvecioğlu, O | 1 |
| Bekpinar, S; Cetinkale, O; Deniz, G; Kiran, B; Olgaç, V; Unlüçerçi, Y; Zilan, A | 1 |
| Carey, RM; Johns, RA; Leiper, JM; Li, D; Millatt, LJ; Siragy, HM; Whitley, GS | 1 |
| Cooke, JP | 1 |
| De Salvatore, G; De Salvia, MA; Mitolo, CI; Mitolo-Chieppa, D; Nacci, C; Natale, L; Piepoli, AL; Porro, C | 1 |
| Berkowitz, DE; Burke, S; Cernetich, A; Champion, HC; Hare, JM; Kim, S; Li, D; Minhas, KM; Nyhan, D; Shoukas, AA; White, R | 1 |
| Banach, M; Bielasik, K; Fila, M; Mussur, M; Okoński, P; Szram, S; Zasłonka, J | 1 |
| Li, SQ; Liang, LJ | 1 |
| Aoki, T; Matsuoka, N; Mihara, K; Moriguchi, A; Mutoh, S; Tojo, N | 1 |
| Bush, RL; Chen, C; Conklin, BS; Johnson, CK; Lin, PH; Lumsden, AB; Pullium, JK | 1 |
| Feng, HM; Huang, XL; Huang, ZH; Lin, HW; Sun, YG | 1 |
| Archer, SL; McMurtry, MS; Michelakis, ED; Sonnenberg, B | 1 |
| Vasar, E; Volke, V; Wegener, G | 1 |
| Babül, A; Erdogan, D; Sayan, H; Take, G; Ugurlu, B | 1 |
| Alonso, MJ; González, R; Martínez-Orgado, J; Salaices, M | 1 |
| Böger, RH | 1 |
| Beffy, P; Bezzi, D; Gross, R; Lajoix, AD; Marchetti, P; Masiello, P; Novelli, M; Pocai, A | 1 |
| Arumugam, TV; Fairlie, DP; Proctor, LM; Reid, RC; Shiels, I; Taylor, SM | 1 |
| Yeh, CL | 1 |
| Iuz'kiv, MIa; Kotsiuruba, AV; Moĭbenko, OO; Tumanovs'ka, LV | 1 |
| Bilgic, H; Korkmaz, A; Oter, S; Oztas, E; Topal, T; Yildirim, I | 1 |
| Brzozowski, T; Konturek, PC; Konturek, SJ; Kwiecień, N; Kwiecień, S; Pawlik, MW; Pawlik, WW | 1 |
| Czakó, L; Góg, C; Hegyi, P; Lonovics, J; Rakonczay, Z; Sári, R; Takács, T | 1 |
| Klahr, S; Morrissey, J | 1 |
| Dai, Z; Deng, HW; Jiang, DJ; Jiang, JL; Li, YJ; Zhu, HQ | 1 |
| Blantz, RC; Deng, A; Gabbai, FB; Khang, S; Lortie, MJ; Munger, KA; Pizzo, DP; Satriano, J; Thareau, S; Thomson, SC | 1 |
| Nishimura, H; Ruiz-Feria, CA; Yang, Y | 1 |
| Bauersachs, J; Schäfer, A | 1 |
| Andersen, ML; Schütz, TC; Tufik, S | 1 |
| Cherian, L; Mendez, DR; Robertson, CS | 1 |
| Isenberg, JS | 1 |
| Brunner, F; Stessel, H; Wölkart, G | 1 |
| Buczko, W; Cylwik, D; Kramkowski, K; Mogielnicki, A; Stokowski, J | 1 |
| Béziel, A; Blanc, MC; Cynober, L; Darquy, S; De Bandt, JP; Moinard, C | 1 |
| Nijveldt, RJ; Rauwerda, JA; Siroen, MP; Teerlink, T; van Lambalgen, AA; van Leeuwen, PA | 1 |
| Déciga-Campos, M; Díaz-Reval, MI; González-Trujano, ME; López-Muñoz, FJ; Ventura-Martínez, R | 1 |
| Espey, MG; Harvey-White, J; Iuliano, BA; Jung, CS; Oldfield, EH; Pluta, RM | 1 |
| Kuroda, Y; Takeyama, Y; Ueda, T | 1 |
| Abreu, GR; Bissoli, NS; Cicilini, MA; Gouvea, SA; Moysés, MR; Pires, JG | 1 |
| Akkari, PA; Cooper, ST; Corbett, MA; Domazetovska, A; Gunning, PW; Hardeman, EC; Laing, NG; North, KN | 1 |
| Anaya-Prado, R; Guo, RF; Reuben, J; Toledo-Pereyra, LH; Walsh, J; Ward, PA | 1 |
| Cabrera, W; Dragani, TA; Falvella, FS; Galbiati, F; Galvan, A; Ibanez, O; Mancuso, MT; Manenti, G; Pazzaglia, S; Pignatiello, C; Saran, A; Spinola, M; Zaffaroni, D | 1 |
| Bernsteyn, A; Coran, AG; Helou, H; Lurie, M; Mogilner, J; Shiloni, E; Sukhotnik, I | 1 |
| Eva, R; Fabry, ME; Fasipe, FR; Ubawike, AE | 1 |
| Gol, A; Kadkhodaee, M | 1 |
| Gerlach, RF; Metzger, IF; Rocha, JB; Souza-Costa, DC; Tanus-Santos, JE; Zerbini, T | 1 |
| Heilig, M; Rimondini, R; Thorsell, A | 1 |
| Bouritius, H; Lamb, KJ; van Hoorn, EC; van Leeuwen, PA; van Limpt, CJ; van Middelaar-Voskuilen, MC; van Norren, K; Vriesema, AJ | 1 |
| Dillon, JP; Kirwan, WO; O'Brien, G; Redmond, HP; Shields, CJ; Winter, DC | 1 |
| Baziliuk, OV; Kotsiuruba, AV; Mehed', OF; Sahach, VF; Stepanenko, LH | 1 |
| Bozic, M; Budihna, MV; Cerne, M; Drevensek, G; Peternel, L; Stalc, A; Stegnar, M; Urleb, U; Zega, A | 1 |
| Kalaiselvi, P; Pragasam, V; Srinivasan, S; Sumitra, K; Varalakshmi, P | 1 |
| Kozar, RA; Moore, FA; Moore-Olufemi, S; Sato, N; Schultz, SG; Smith, MA; Zou, L | 1 |
| Bode-Böger, SM | 1 |
| Cusick, MC; Primeaux, SD; Wilson, MA; Wilson, SP; York, DA | 1 |
| Fedorovich, AA; Krivoruchko, IA | 1 |
| Banach, M; Mussur, M; Okoński, P; Szram, S; Zasłonka, J | 1 |
| Bath, PM; Gibson, C; Gray, L; Murphy, S; Willmot, M | 1 |
| Ghetti, B; Harris, DA; Piccardo, P; Stewart, RS | 1 |
| Aigner, C; Fink, L; Ghofrani, HA; Grimminger, F; Haredza, P; Kiss, L; Klepetko, W; Muyal, JP; Pullamsetti, S; Schermuly, RT; Seeger, W; Voswinckel, R; Weissmann, N | 1 |
| Bing, W; Chaoshu, T; Hui, Y; Jian, L; Jianguang, Q; Junbao, D | 1 |
| Ahmed, Z; Batchelor, AM; Cuzner, ML; Garthwaite, G; Garthwaite, J; Goodwin, DA; Hewson, AK; Leeming, K | 1 |
| Coran, AG; Lerner, A; Lurie, M; Miselevich, I; Mogilner, JG; Shiloni, E; Sukhotnik, I | 1 |
| Achan, V; Cooke, JP; Heeschen, C; Ho, HK; Jang, JJ; Kimoto, M; Stuehlinger, M; Vallance, P | 1 |
| Brown, L; Fenning, A; Harrison, G; Hoey, A; Rose'meyer, R | 1 |
| Kurup, VP; Manickam, P; Raju, R | 1 |
| Hardman, J; McMahon, R; Redmond, HP; Schofield, D; Shields, C; Siriwardena, AK | 1 |
| Alwahdani, A; Chu, Y; Faraci, FM; Heistad, DD; Iida, S; Lund, DD | 1 |
| Lentz, SR | 1 |
| Bonet, B; Fernández-Frutos, B; Fernández-López, D; González, R; Martínez-Orgado, J; Moro, M; Romero, E; Urigüen, L; Viveros, MP | 1 |
| Ferreira, PK; Kaster, MP; Rodrigues, AL; Santos, AR | 1 |
| De la Porte, S; Gillet, B; Israël, M; Matecki, S; Ramonatxo, M; Sébrié, C; Voisin, V; Yu, H | 1 |
| Hua, Y; Karabiyikoglu, M; Keep, R; Xi, G | 1 |
| Acin, S; Arbones-Mainar, JM; Arnal, C; Carnicer, R; Guillen, N; Martinez-Gracia, MV; Navarro, MA; Osada, J; Sarria, AJ; Surra, JC | 1 |
| Chu, SJ; Lee, TY; Li, MH; Lin, SH; Yan, HC | 1 |
| Bianchi, C; Feng, J; Malik, T; Nakai, Y; Rosinberg, A; Sellke, FW; Voisine, P; Xu, SH | 1 |
| Cerasi, E; Efendic, S; Kaiser, N; Nesher, R; Oprescu, A | 1 |
| Chen, B; Chen, ZH; Fu, JF; Li, CP; Luo, ZH; Wang, H; Xu, Y; Yuan, WH | 1 |
| Hardman, J; Jamdar, S; McMahon, R; Redmond, HP; Shields, C; Siriwardena, AK | 1 |
| Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Nangaku, M; Shibata, T; Sugiyama, S; Usuda, N; van Ypersele de Strihou, C | 1 |
| Angele, MK; Faist, E; Loehe, F | 1 |
| Seftel, A | 1 |
| Aizawa, T; Inagi, R; Izuhara, Y; Kurokawa, K; Miyata, T; Nangaku, M; Tominaga, N; van Ypersele de Strihou, C | 1 |
| Botti, C; Byrns, RE; de Nigris, F; de Rosa, G; Farzati, B; Fiore, A; Ignarro, LJ; Lerman, LO; Matarazzo, A; Napoli, C; Sica, G; Sica, V; Sumi, D; Williams-Ignarro, S | 1 |
| Hay, WW; Hutton, JC; Limesand, SW; Rozance, PJ; Zerbe, GO | 1 |
| Dudhgaonkar, SP; Kumar, D; Naik, AK; Tandan, SK | 1 |
| Garrison, RN; Hurt, RT; Matheson, PJ; Mays, MP | 1 |
| Almeida, RC; Felisbino, CS; Gabilan, NH; López, MG; Rodrigues, AL | 1 |
| Alber, H; Dulak, J; Frick, M; Hügel, H; Jozkowicz, A; Millonig, G; Pachinger, O; Schwarzacher, SP; Weidinger, F; Weiss, C; Zwick, RH | 1 |
| Dayal, S; Lentz, SR | 1 |
| Maas, R | 1 |
| Grady, EF; Kirkwood, KS; Pikios, S; Wick, EC | 1 |
| Rothenberg, ME; Zimmermann, N | 1 |
| Iijima, T; Inoue, K; Inoue, S; Kurane, I; Morimoto, K; Sakai, T; Shoji, Y; Takayama-Ito, M | 1 |
| Gunning, Y; Hopkins, N; Laffey, JG; McLoughlin, P; O'Croinin, DF | 1 |
| Okuducu, H; Onal, SA | 1 |
| Jakobsen, P; Martínez, AC; Simonsen, U; Stankevicius, E | 1 |
| Arumugam, T; Ernst, SA; Kubisch, CH; Logsdon, CD; Sans, MD; Williams, JA | 1 |
| Maksimovich, NE; Maslakov, DA; Zinchuk, VV | 1 |
| Burneckiene, J; Rodovicius, H | 1 |
| Annat, G; Arnal, F; Cespuglio, R; Crova, P; Goudable, J; Lhuillier, F; Robert, MO; Viale, JP | 1 |
| Baudry, N; Duranteau, J; Nakajima, Y; Vicaut, E | 1 |
| Amini, R; Rassouli, Y; Rezayof, A; Zarrindast, MR | 1 |
| Eroglu, L; Ozek, M; Sevgi, S | 1 |
| Bhattacharya, SK; Bonilha, VL; Crabb, JS; Crabb, JW; Gu, X; Takahara, H | 1 |
| Ijames, SG; Lysle, DT; Saurer, TB | 1 |
| Chen, CY; Cooley, BC; Schmeling, G | 1 |
| Chang, B; Cheng, C; Cheung, D; Gong, X; Horwitz, J; Huang, Q; Liu, H; Wang, M; Xia, CH | 1 |
| Buyukbayram, H; Ozturk, H; Yagmur, Y | 1 |
| Byrns, RE; D'Armiento, FP; de Nigris, F; Fiorito, C; Ignarro, LJ; Lerman, LO; Napoli, C; Sica, G; Sica, V; Williams-Ignarro, S | 1 |
| De Witte, P; Dravolina, O; Lallemand, F; Ward, RJ | 1 |
| Belabed, L; Besson, V; Charrueau, C; Chaumeil, JC; Cynober, L; Gupta, S; Marchand-Verrecchia, C; Moinard, C | 1 |
| Brunini, TM; Ellory, JC; Mann, GE; Mendes Ribeiro, AC; Moss, MB; Roberts, NB; Siqueira, MA; Yaqoob, MM | 1 |
| Leusink, J; Maarsingh, H; Meurs, H; Zaagsma, J | 1 |
| Belmonte, C; Carreño, C; Fernández-Carvajal, A; Ferrer-Montiel, A; Ferroni, S; García-Martínez, C; Gomis, A; Valenzuela, B; Van Den Nest, W | 1 |
| Pessah, IN; Ta, TA | 1 |
| Aspelin, T; Björkman, JA; Eriksen, M; Ilebekk, A; Lyberg, T; Nordlander, M; Sevre, K | 1 |
| Bödeker, H; Gaiser, S; Keim, V; Klöppel, G; Mössner, J; Sack, U; Savkovic, V; Selig, L | 1 |
| Bhagat, L; Dawra, RK; Navina, S; Saluja, AK; Sharif, R; Singh, VP | 1 |
| Bier, GE; Brofman, PR; da Silva, RF; de Moraes, JD; Knopfholz, J; Lemos, AC; Précoma, DB; Silva, AP; Silva, Pde O | 1 |
| Dasgupta, T; Hebbel, RP; Kaul, DK | 1 |
| Dawra, R; Dhaulakhandi, D; Dudeja, V; Phillips, P; Saluja, AK; Sharif, R | 1 |
| Chernichovski, T; Chernin, G; Ingbir, M; Levo, Y; Litvak, A; Reshef, R; Schwartz, D; Schwartz, IF; Weinstein, T | 1 |
| Chichester, P; Levin, RM; Sokol, R; Whitbeck, C | 1 |
| Agata, N; Ebihara, T; Kawai, T; Lin, CY; Mukherjee, PM; Olsen, BR; Onji, M; Reichenberger, E; Saheki, Y; Senoo, M; Ueki, Y | 1 |
| Engel, JA; Fejgin, K; Klamer, D; Pålsson, E; Svensson, L; Wass, C | 1 |
| Ishida, H; Iwata, M; Katayama, S; Kawahara, R; Nakagome, K; Shirayama, Y; Yamamoto, A | 1 |
| Hasegawa, K; Hayashi, K; Homma, K; Kanda, T; Kimoto, M; Saruta, T; Sugano, N; Tatematsu, S; Wakino, S; Yoshioka, K | 1 |
| Scher, RL | 1 |
| Chatterjee, S; Poduval, TB; Premachandran, S; Shukla, J | 1 |
| Abitbol, M; Deybach, JC; Guénet, JL; Montagutelli, X; Puy, H; Sabaté, JM | 1 |
| Cardoso, VN; Correia, MI; Quirino, IE | 1 |
| Chen, C; El Sayed, HF; Kougias, P; Lin, PH; Okada, T; Rawat, A; Steinberg, JL; Yao, Q; Zhou, W | 1 |
| Awad, AA; El Desoky, I; Hussein, Ael-A; Mahmoud, IM; Sarhan, ME | 1 |
| Arnolda, LF; Holobotovskyy, VV; Malik, V; McKitrick, DJ; Phillips, JK | 1 |
| Cooke, JP; Konishi, H; Sydow, K | 1 |
| Andria, G; Annunziata, P; Ballabio, A; Borsani, G; Bozzato, A; Corso, G; D'Armiento, M; Maiuri, L; Piccolo, P; Sebastio, G; Sperandeo, MP | 1 |
| Branzi, A; Coccolo, F; Cooke, JP; Fallani, F; Ferrara, R; Grigioni, F; Lewis, DB; Magelli, C; Magnani, G; Mocarski, ES; Potena, L; Valantine, HA | 1 |
| Fukami, K; Imaizumi, T; Matsuguma, K; Matsumoto, Y; Matsuoka, H; Okuda, S; Shibata, R; Ueda, S; Yamagishi, S | 1 |
| Belmadani, S; Chilian, WM; Feldman, AM; Gao, X; Park, Y; Tang, Z; Xu, X; Zhang, C | 1 |
| Jeremy, RW; McCarron, HC; Prasan, AM; Zhang, Y | 1 |
| Bentzer, P; Lundblad, C | 1 |
| Belforte, N; Bordone, M; Cymeryng, C; Keller Sarmiento, MI; Moreno, MC; Rosenstein, RE | 1 |
| Battaglia, M; Bosticardo, M; Casati, A; Cavazzana-Calvo, M; Facchetti, F; Frascoli, L; Gougeon, ML; Grassi, F; Lemercier, B; Marrella, V; Notarangelo, LD; Poliani, PL; Ravanini, M; Roncarolo, MG; Rucci, F; Vezzoni, P; Villa, A | 1 |
| Kääpä, P; Kiss, J; Savunen, T | 1 |
| Buyukbayram, H; Ozturk, H; Tuncer, MC | 1 |
| Beier, DR; Cockroft, JL; Goldowitz, D; Matera, I; Moran, JL; Pavan, WJ | 1 |
| Aranda, JV; Glibetic, M; Natarajan, G; Ofenstein, JP; Raykova, V; Thomas, RL | 1 |
| Deng, HW; Guo, R; Jia, SJ; Jiang, DJ; Li, NS; Li, YJ; Xiao, HB; Yang, ZC; Zhang, XH; Zhou, Z | 1 |
| Bouhaddi, M; Davani, S; Kantelip, JP; Reyssie, H; Rochette, L; Royer, B; Vergely, C | 1 |
| Ferraro, G; Sardo, P | 1 |
| Brinkley, BR; Cai, WW; Caulin, C; Goepfert, TM; Lang, GA; Lozano, G; Nguyen, T; Roop, DR | 1 |
| Brack, KE; Coote, JH; Ng, GA; Patel, VH | 1 |
| Miao, Y; Quinn, TP; Shelton, T | 1 |
| Marmorstein, AD; Marmorstein, LY; McLaughlin, PJ; Peachey, NS; Sasaki, T | 1 |
| Agar, E; Ayyildiz, M; Bosnak, M; Yildirim, M | 1 |
| Jiang, X; Li, J; Li, N; Tan, L; Zhu, W | 1 |
| Katayama, Y; Katsumata, T; Nishiyama, Y; Otori, T; Tanaka, N | 1 |
| Boodhwani, M; Clements, RT; Feng, J; Sellke, FW; Sodha, NR; Xu, SH | 1 |
| Liao, KX; Liu, JF; Luo, YQ; Ren, YF; Wu, CT | 1 |
| Louro, T; Matafome, P; Moreira, PI; Nunes, E; Peixoto, F; Santos, MS; Seiça, R; Sena, CM | 1 |
| Kunes, J; L'upták, I; Matúsková, J; Pechánová, O; Simko, F; Török, J; Zicha, J | 1 |
| Das, P; Dong, W; Ji, Y; Miksa, M; Ravikumar, TS; Wang, P; Wu, R; Yang, D; Zhang, F; Zhou, M | 1 |
| Aslan, A; Kars, HZ; Ozüm, U; Taş, A | 1 |
| Castillo, L; Erez, A; Lee, B; Marini, JC | 1 |
| Macarthur, H; Westfall, TC; Wilken, GH | 1 |
| Morris, CE; Skalak, TC | 1 |
| Akaishi, S; Endo, T; Hojo, N; Kobayashi, M; Kudo, D; Nomura, R; Sasaki, J; Shinozawa, Y; Takuma, K; Xie, XQ; Yamanouchi, S | 1 |
| Bağirici, F; Bostanci, MO | 1 |
| Lei, ST; Liu, JF; Ren, YF; Wu, CT; Zhang, JH | 1 |
| Huang, CJ; Huang, TY; Tsai, PS | 1 |
| Brown, RD; Carlström, M; Edlund, J; Larsson, E; Palm, F; Persson, AE; Sällström, J; Teerlink, T; Wåhlin, N | 1 |
| Dubinion, JH; Jackson, EK; Mi, Z | 1 |
| An, Q; Chen, HJ; Deng, SZ; Dian, K; Du, L; Jia, MX; Liu, J; Wang, W; Yang, PL | 1 |
| Jiang, JM; Liu, JY; Yin, XY; Zhu, JR | 1 |
| Brito, GA; Gadelha, GG; Garcia, JA; Lima, SJ; Medeiros, JV; Ribeiro, RA; Santos, AA; Soares, PM; Souza, MH | 1 |
| Duffin, R; Rossi, AG; Shaw, CA | 1 |
| Adiloglu, AK; Akturk, O; Altuntas, I; Kapucuoğlu, N; Kiris, I; Okutan, H; Savas, C | 1 |
| Deppert, W; Heinlein, C; Krepulat, F; Löhler, J; Speidel, D; Tolstonog, GV | 1 |
| Ito, M; Kumakura, S; Nishizawa, M; Ogura, T; Okuma, K; Sugiura, W; Tanaka, R; Tanaka, Y; Yamamoto, N; Yanaka, M | 1 |
| Bavaresco, CS; Delwing, D; Wyse, AT | 1 |
| Connolly, ES; Ducruet, AF; Fusco, DJ; Hassid, BG; Hickman, ZL; Kim, GH; Komotar, RJ; Mack, WJ; Mocco, J; Otten, ML; Sosunov, SA | 1 |
| Coccaro, MR; Foster, DM; Gookin, JL; Stauffer, SH | 1 |
| Chen, L; Chen, Z; Deng, C; Du, X; Jin, M; Li, C; Li, F; Qi, H; Su, N; Xu, X; Xue, J; Yang, J; Yin, L; Zhao, L | 1 |
| Manucha, W; Vallés, PG | 1 |
| Debaveye, Y; Ellger, B; Langouche, L; Richir, MC; Teerlink, T; Van den Berghe, G; van Leeuwen, PA; Vanhorebeek, I | 1 |
| Castillo-Henkel, C; Escalante, B; Jarillo Luna, RA; Medina-Santillan, R; Mendoza, MG; Rios, A; Robles, HV; Romo, E | 1 |
| Fahim, M; Shahid, M; Sharma, KK; Tauseef, M | 1 |
| Buko, VU; Lis, R; Lukivskaya, O; Patsenker, E | 1 |
| Duan, W; Jiang, M; Li, Q; Liang, Y; Masuda, N; Peng, Q; Ross, CA; Wang, W; Wang, X; Zhao, M | 1 |
| Gunawardana, SC; Head, WS; Piston, DW | 1 |
| Santillán, RM | 1 |
| Jovović, D; Mihailović-Stanojević, N; Milanović, JG; Milanović, S; Miloradović, Z | 1 |
| Avila, MA; DeWitt, DS; Grady, JJ; Prough, DS; Sell, SL; Vergara, L; Yu, G | 1 |
| Duda, E; Eder, K; Lázár, G; Paszt, A; Szabolcs, A; Takács, T; Tiszlavicz, L | 1 |
| Maarsingh, H; Meurs, H; Pera, T | 1 |
| Chen, J; Huang, HS; Ma, MC | 1 |
| Dasgupta, T; Fabry, ME; Kaul, DK; Zhang, X | 1 |
| Brunini, TM; Ferraz, MR; Mendes-Ribeiro, AC; Okinga, A; Pinto, VL | 1 |
| Lentz, SR; Rodionov, RN | 1 |
| Gladwin, MT; Hsu, LL; Krajewski, ML | 1 |
| Bonner-Weir, S; Clore, ET; Weir, GC; Zmachinski, CJ | 1 |
| Adriaenssens, K; Karcher, D; Lowenthal, A; Marescau, B; Terheggen, HC; Van Broeckhoven, C | 1 |
| Deshmukh, DR; Maassab, HF; Mason, M | 1 |
| Conaway, HH; Faas, FH; Sanders, LL; Smith, SD | 1 |
| Baublis, JV; Deshmukh, DR; Kao, W; Maassab, HF; Mason, M | 1 |
| Heidland, A; Hempel, K; Neff, N; Schmid, G | 1 |
| Eneroth, A; Kristensson, K; Olsson, T; Wiesenfeld-Hallin, Z | 1 |
| Garside, P; Liew, FY; Mowat, AM; Severn, A | 1 |
| Chen, PY; Sanders, PW | 1 |
| Ohno, M; Watanabe, S; Yamamoto, T | 1 |
| Currie, MG; Masferrer, JL; Misko, TP; Needleman, P; Salvemini, D; Seibert, K | 1 |
| Coffey, JW; Evans, CH; Hoffman, RA; Meschter, C; Meyers, K; Stefanovic-Racic, M | 1 |
| Grinstein, S; Orn, A; Petray, P; Rottenberg, ME | 1 |
| Honda, Y; Iwaki, M; Mandai, M; Yoshida, M; Yoshimura, N | 1 |
| Lüscher, TF; Noll, G; Novosel, D; Tschudi, MR | 1 |
| Martin, CM; Sibbald, WJ | 1 |
| Gebhart, GF; Meller, ST | 1 |
| Shudo, H | 1 |
| Cheng, W; Cunningham, JN; Damiani, P; Henderson, JL; Horovitz, JH; Siconolfi, A; Statman, R | 1 |
| Caldwell, M; Earley, B; Leonard, B; O'Neill, M | 1 |
| Economidou, D; Leontsini, M; Margari, P; Papadimitriou, M; Raidis, C; Vakianis, P; Vrettos, M | 1 |
| Agarwal, N; Chalasani, S; Lentz, KE; Lomis, TJ; Lowenstein, CJ; McMillan, A; Rhoads, JE; Siffring, CW; Stauffer, KE; Ziegler, DW | 1 |
| Heidbreder, E; Heidland, A; Kartenbender, K; Ling, H; Schmitt, A; Schramm, L; Zimmermann, J | 1 |
| Chen, SJ; Wu, CC; Yen, MH | 1 |
| Broner, CW; O'Dorisio, MS; O'Dorisio, TM; Rosenberg, RB | 1 |
| Bass, J; Di Lorenzo, M; Krantis, A | 1 |
| Bellot, J; Courtois, Y; de Kozak, Y; Goureau, O; Thillaye, B | 1 |
| Gerecke, U; Koch, R; Löscher, W; Mevissen, M; Richter, A; Rundfeldt, C | 1 |
| Chen, SJ; Szabó, C; Thiemermann, C; Vane, JR; Wu, CC | 1 |
| Albino-Teixeira, A; Fernandes, MH; Pestana, M; Soares-da-Silva, P; Vieira-Coelho, MA | 1 |
| Heinemann, A; Stauber, RE | 1 |
| Offner, PJ; Pruitt, BA; Robertson, FM | 1 |
| Bursztyn, M; Karmeli, F; Okon, E; Rachmilewitz, D | 1 |
| Choi, KC; Kim, W; Lee, J; Park, JW; Yeum, CH; Yoo, K; Yoon, PJ | 1 |
| Küng, CF; Lüscher, TF; Moreau, P; Schaffner, T; Takase, H; van Rooijen, MM | 1 |
| Pinto, A; Sorrentino, R | 1 |
| Lupini, M; Mannaioni, PF; Masini, E; Mugnai, L; Raspanti, S | 1 |
| Camporesi, EM; Hakim, TS; Oleary, CE; Picone, A | 1 |
| Barbul, A; Gardiner, KR; Gardiner, RE | 1 |
| Héron, A; Pinard, E; Rigaud-Monnet, AS; Seylaz, J | 1 |
| Ayuse, T; Boitnott, JK; Brienza, N; Revelly, JP; Robotham, JL | 1 |
| Bloch, DA; Cooke, JP; Singer, AH; Tsao, PS; Wang, BY | 1 |
| Hirose, H; Ide, K; Ikemoto, F; Kobayashi, M; Nishikibe, M; Sasaki, T; Takahashi, R; Yano, M | 1 |
| Bass, P; Gaumnitz, EA; Osinski, MA; Singaram, C; Sweet, MA | 1 |
| Fogt, F; Greenberg, SS; Loscalzo, J; Nanji, AA; Sadrzadeh, SM; Stamler, JS; Tahan, SR; Xie, J | 1 |
| Chen, RN; Inman, SR; Novick, AC; Stowe, NT | 1 |
| Chotinaruemol, S; Clark, DA; Kakkis, JL; Miller, MJ; Sadowska-Krowicka, H | 1 |
| Holmer, S; Krämer, BK; Kurtz, A; Riegger, G; Schricker, K | 1 |
| Fineman, JR; Soifer, SJ; Vanderford, PA; Winters, J; Wong, J | 1 |
| Appay, MD; Arnal, JF; Bariety, J; Hinglais, N; Laboulandine, I; Michel, JB; Xu, Y | 1 |
| Feria, M; Niedbala, B; Sánchez, A | 1 |
| Brass, CA; Ischiropoulos, H; Ma, TT | 1 |
| Chamulitrat, W; Jordan, SJ; Litton, AL; Mason, RP; Molina y Vedia, L; Wilson, JG; Wolberg, G; Wood, ER | 1 |
| Nakashima, M; Nishiyama, H; Saniabadi, AR; Takiguchi, Y; Uematsu, T; Umemura, K | 1 |
| Carnuccio, R; Di Rosa, M; Iuvone, T | 1 |
| Badr, KF; Ferrario, R; Fogo, A; Munger, KA; Takahashi, K | 1 |
| Hussain, SN; Ward, ME | 1 |
| Cioffi, WG; Johnson, AA; Jordan, BS; Offner, PJ; Ogura, H; Pruitt, BA; Saitoh, D | 1 |
| Campbell, C; Napolitano, LM | 1 |
| Kanzaki, T; Mori, M; Murakami, T; Noda, T; Saheki, T; Shimada, T; Takiguchi, M; Tashiro, M; Yamamura, K | 1 |
| Aldras, AM; Bohm, R; Didier, ES; Didier, PJ; Millichamp, NJ; Murphey-Corb, M; Shadduck, JA; Varner, PW | 1 |
| Griffith, TM; Randall, MD; Ujiie, H | 1 |
| Antonini, JM; Reasor, MJ; Van Dyke, K; Wu, L; Ye, Z | 1 |
| Hamada, Y; Hattori, H; Hayakawa, T; Mikawa, H | 1 |
| Chan, CC; Cheung, MK; Parks, DJ; Roberge, FG | 1 |
| García-Robles, R; Martínez, FJ; Romero, JC; Villa, E | 1 |
| Bloch, KD; Chen, TY; Kawai, N; Rovira, I; Winkler, M; Zapol, WM | 1 |
| Imura, H; Ishida, H; Kato, S; Kurose, T; Okada, Y; Okamoto, Y; Seino, Y; Taminato, T; Tsuji, K; Tsuura, Y | 1 |
| Caplan, M; Hsueh, W; MacKendrick, W | 1 |
| Kirchner, KA; Layne, S; Patel, A; Watts, D | 1 |
| Delaney, CP; Dervan, P; Fitzpatrick, JM; McGeeney, KF | 1 |
| Klabunde, RE; Ritger, RC; Slayton, KJ | 1 |
| Meadow, W | 1 |
| Descombes, JJ; Laubie, M; Mennecier, P; Porro de Bailliencourt, J; Simonet, S; Verbeuren, TJ | 1 |
| Arnal, JF; el Amrani, AI; Michel, JB | 1 |
| Laychock, SG; Xia, M | 1 |
| Cosentino, F; Katusić, ZS; Milde, JH; Mitrović, BS | 1 |
| Baudouin, SV; Evans, TW | 1 |
| De Pablo, R; Jorge, P; Landín, L; Liste, D; Lorente, JA; Renes, E; Ródena, E | 1 |
| Ku, NO; Michie, S; Omary, MB; Oshima, RG | 1 |
| Thiemermann, C | 1 |
| Johnston, MV; Taylor, GA; Traystman, RJ; Trescher, WH | 1 |
| Ashwal, S; Cole, DJ; Osborne, S; Osborne, TN; Pearce, WJ | 1 |
| Aldoretta, PA; Anderson, SM; Carver, TD; Esler, AL; Hay, WW | 1 |
| Clark, DA; Eloby-Childress, S; Miller, MJ; Pierce, MR; Voelker, CA; Zhang, XJ | 1 |
| Demolombe, B; Laurant, P | 1 |
| Blanc, T; Kaeffer, N; Richard, V; Thuillez, C; Tron, C | 1 |
| Fujita, K; Matsumura, Y; Miyazaki, Y; Morimoto, S; Takaoka, M | 1 |
| Kawai, H; Nakashima, M; Umemura, K | 1 |
| Küng, CF; Lüscher, TF; Moreau, P; Takase, H | 1 |
| Béa, ML; Berdeaux, A; Ghaleh, B; Giudicelli, JF; Puybasset, L; Simon, L | 1 |
| Leong, SK; Ruan, RS; Yeoh, KH | 1 |
| Pfeiffer, CJ; Qiu, BS | 1 |
| Ali, AT | 1 |
| Ogilvie, RI; Zborowska-Sluis, D | 1 |
| Akatsuka, Y; Egashira, K; Katsuda, Y; Narishige, T; Shimokawa, H; Takeshita, A | 1 |
| Billiar, TR; Harbrecht, BG; Marshall, HP; Peitzman, AB; Watkins, SC; Wu, B | 1 |
| Hangai, M; Iwaki, M; Kogishi, J; Mandai, M; Mittag, TW; Yoshimura, N | 1 |
| Ibrahim, IN; Kadowitz, PJ; Kaye, AD; Nossaman, BD | 1 |
| Bina, S; Grissom, TE; Hart, J; Muldoon, SM | 1 |
| Ahlin, KA; Frank, MW; Harris, KR; Klocke, FJ | 1 |
| Dijkstra, CD; Huitinga, I; Ruuls, SR; Sontrop, K; Van Der Linden, S | 1 |
| Albaya, A; Cañas, P; Delgado, MA; Jorge, P; Landin, L; Liste, D; Lorente, JA; Renes, E | 1 |
| Lipsitz, EC; Smerling, AJ; Stolar, CJ; Weinstein, S | 1 |
| Guarner, F; Malagelada, JR; Mourelle, M; Salas, A; Vilaseca, J | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; March, JE | 1 |
| Gardiner, KR; Kirk, SJ; Neilly, PJ; Rowlands, BJ | 1 |
| Fukatsu, K; Fukushima, R; Furukawa, S; Han, I; Inaba, T; Inoue, T; Lin, MT; Muto, T; Saito, H | 1 |
| Cuéllar, B; Leza, JC; Lizasoain, I; Lorenzo, P; Moro, MA | 1 |
| Chatterjee, K; Glantz, SA; Parmley, WW; Shuman, JL; Sievers, RE; Sun, Y; Wolfe, CL; Zhu, B | 1 |
| Aranow, JS; Fink, MP; Larkin, V; Smith, M; Wang, H; Zhuang, J | 1 |
| Booke, M; Hinder, F; McGuire, R; Traber, DL; Traber, LD | 1 |
| Buéno, L; Fargeas, MJ; Fioramonti, J; Theodorou, V; Weirich, B | 1 |
| De Marco, G; Gangula, P; Wimalawansa, SJ; Yallampalli, C | 1 |
| Daughters, K; Nguyen, H; Waxman, K | 1 |
| Burnstock, G; Mathie, RT; Moore, KP; Ralevic, V | 1 |
| Berry, CN; Duval, N; Grosset, A; Lunven, C; O'Brien, DP; O'Connor, SE | 1 |
| Kawai, H; Sugimoto, J; Tamao, Y; Yuki, S | 1 |
| Gerová, M; Masánová, C; Pavlásek, J | 1 |
| Anderson, N; Hoper, M; Ma, Q; Rowlands, BJ | 1 |
| duPlessis, A; Forbess, JM; Hiramatsu, T; Holtzman, D; Jonas, RA; Miura, T; Tanji, M | 1 |
| Berry, CN; Girard, D; Girardot, C; Lochot, S; Lunven, C; Visconte, C | 1 |
| Börjesson, I; Elg, M; Gustafsson, D; Lenfors, S; Teger-Nilsson, AC | 1 |
| Blight, AR; Cohen, TI; Weinberg, RJ | 1 |
| Chapman, AG; Man, CM; Meldrum, BS; Smith, SE; Tang, E; Yip, PK | 1 |
| Aoki, N; Fujimori, Y; Kawai, K; Nakamura, F; Omata, M; Sakamoto, Y; Tomaru, T; Uchida, Y | 1 |
| Aoki, N; Nakamura, F; Omata, M; Sakamoto, Y; Tomaru, T; Uchida, Y | 1 |
| Bailbé, D; Berthelier, C; Picarel-Blanchot, F; Portha, B | 1 |
| Bittner, HB; Chen, EP; Geiger, MI; Guice, KS; Kendall, SW; Van Trigt, P | 1 |
| Mizuno, A; Noma, Y; Sano, T; Shima, K; Zhu, M | 1 |
| Gustafsson, D; Lenfors, S | 1 |
| Cosso, L; Marinari, UM; Noberasco, G; Odetti, P; Pronzato, MA; Traverso, N | 1 |
| Ao, L; Banerjee, A; Brown, JM; Fullerton, DA; Harken, AH; Meng, X | 1 |
| Amann, G; Aufricht, C; Höger, H; Kitzmüller, E; Lubec, B | 1 |
| Noble, NA; Peters, H | 1 |
| Burnett, AL; Calvin, DC; Chamness, SL; Dawson, TM; Dawson, VL; Klein, SL; Liu, JX; Nelson, RJ; Snyder, SH | 1 |
| Sanders, PW | 1 |
| Giddings, JC; Kawano, M; Sasaki, Y; Watanabe, S; Yamamoto, J | 1 |
| Deyl, Z; Kunes, J; Miksík, I; Zicha, J | 1 |
| Delbro, DS; Nilsson, B | 1 |
| Kambayashi, J; Kawasaki, T; Kim, DI; Sakon, M; Shibuya, T | 1 |
| Chen, G; Koyama, K; Lee, Y; Newgard, CB; Shimabukuro, M; Unger, RH; Wang, MY | 1 |
| Moore-Hilton, G; Pieper, GM; Roza, AM; Siebeneich, W | 1 |
| Adawi, D; Jeppsson, B; Molin, G | 1 |
| Kawaguchi, A; Matsuda, H; Miyatake, K; Nagata, S; Tamai, J; Uematsu, M | 1 |
| Nonami, Y | 1 |
| Nakamura, T | 1 |
| Bazzani, C; Bertolini, A; Guarini, S | 1 |
| Andreucci, M; Bellizzi, V; Cianciaruso, B; De Nicola, L; La Verde, A; Minutolo, R | 1 |
| Baron, AD; Fei, L; Henry, DP; Zipes, DP | 1 |
| Hara, T; Kunitada, S; Morishima, Y; Tanabe, K; Terada, Y | 1 |
| Kostowski, W; Krzaścik, P | 1 |
| Caramia, F; Hamberg, LM; Huang, Z; Hunter, G; Moskowitz, MA; Rosen, BR; Wanke, I; Yoshida, T; Zaharchuk, G | 1 |
| Berry, CN; Charles, MC; Ferrari, P; Girard, D; Girardot, C; Lechaire, I; Lunven, C; O'Brien, DP | 1 |
| Kikumoto, R; Tamao, Y | 1 |
| Hirayama, F; Kawasaki, T; Koshio, H; Matsumoto, Y; Sakai, Y; Sato, K; Taniuchi, Y | 1 |
| Broca, C; Gross, R; Hillaire-Buys, D; Manteghetti, M; Masiello, P; Novelli, M; Ribes, G; Roye, M | 1 |
| Pavlov, VA | 1 |
| Cox, FE | 1 |
| Horie, K; Kyogashima, M; Miyauchi, S; Mizuno, S; Onaya, J; Sunose, A | 1 |
| Bemanian, S; Kivlighn, SD; Ni, Z; Vaziri, ND | 1 |
| Cho, OJ; Cohen, Z; Hybertson, BM; Repine, JE; Stringer, KA | 1 |
| Bährle, S; Bátkai, S; Dengler, TJ; Hagl, S; Stumpf, N; Szabó, G; Vahl, CF; Zimmermann, R | 1 |
| Chen, PY; Hamm, DA; Sanders, PW; Wood, PA | 1 |
| Burakoff, R; Homaidan, FR; Martello, LA; Melson, SJ | 1 |
| Beaudet, AL; Dennis, JA; Frazer, M; Healy, PJ; Lee, B; Mull, B; O'Brien, WE; Patejunas, G; Reeds, PJ; Warman, AW; Yu, H | 1 |
| Brzozowski, T; Hahn, EG; Konturek, PC; Konturek, SJ; Pajdo, R; Sliwowski, Z; Stachura, J | 1 |
| Alagarsamy, S; DeWitt, DS; Johnson, KM | 1 |
| Capurro, D; Donoso, V; Huidobro-Toro, JP; Mezzano, V | 1 |
| Dayao, EK; Hauser, GJ; Qureshi, NU; Shirali, S; Zukowska-Grojec, Z | 1 |
| Hermon, M; Hoeger, H; Lubec, B; Lubec, G | 1 |
| Baylis, C; Zatz, R | 1 |
| Hua, TC; Moochhala, SM | 1 |
| Angele, MK; Ayala, A; Bland, KI; Chaudry, IH; Cioffi, WG; Smail, N | 1 |
| Chen, C; Lumsden, AB; Mattar, SG | 1 |
| Datta, P; Javeshghani, D; Levy, RD; Magder, S; Mehta, S | 1 |
| Bauters, C; Bertrand, ME; Corseaux, D; Dupuis, B; Lablanche, JM; Le Tourneau, T; Lebuffe, G; McFadden, E; Vallet, B; Van Belle, E | 1 |
| Schultz, HD; Sun, SY; Wang, W; Zucker, IH | 1 |
| Campos, SB; Dórea, EL; Ori, M; Seguro, AC | 1 |
| Border, WA; Noble, NA; Peters, H | 1 |
| Becker, EJ; Hester, RK; Jeffrey, JS; Martinez-Lemus, LA; Odom, TW | 1 |
| Hehmke, B; Kessler, J; Klöting, I; Kohnert, KD | 1 |
| Ayuso, D; Delgado, MA; Esteban, A; Fernández-Segoviano, P; Hervás, M; Lorente, JA; Mon, E; Pascual, T; Rieppi, G; Soler, A; Tejedor, C | 1 |
| Chacko, G; Cherian, L; Goodman, JC; Robertson, CS | 1 |
| Goldfarb, RD; Kilbourn, RG | 1 |
| Blatchford, GJ; Christensen, MA; Lin, KM; Shashidharan, M; Smyrk, TC; Ternent, CA; Thorson, AG | 1 |
| Afshar, JK; Boock, RJ; Harvey-White, J; Oldfield, EH; Pluta, RM; Thompson, BG | 1 |
| Milam, AH; Steel, G; Valle, D; Wang, T | 1 |
| Ito, M; Koyama, H; Maeda, T; Ohshige, A; Okamura, H; Yoshimura, T | 1 |
| de Vasconcelos, AP; Gizard, F; Marescaux, C; Nehlig, A | 1 |
| Davenport, DJ; Fettman, MJ; Gross, KL; Hand, MS; Hansen, RA; Mallinckrodt, CH; Ogilvie, GK; Richardson, KL; Rogers, Q; Walton, JA | 1 |
| Cernak, I; Malicević, Z; Pavlović, R; Savić, V; Zunic, G | 1 |
| Hatakeyama, K; Kelly, KA; Marinos, RS; Martinez-Zaguilan, R; Meininger, CJ; Rojas, JD; Wu, G | 1 |
| Berry, CN; Girard, D; Lecoffre, C; Lochot, S; Visconte, C | 1 |
| Jang, IK; Sabatine, MS; Tu, TM | 1 |
| Fukuda, K; Hosokawa, M; Kodama, M; Nakamura, H; Ohya, M; Onomura, M; Seino, Y; Tsukada, H | 1 |
| Burçak, G; Inci, F; Oz, B; Seven, A; Seymen, O; Yiğit, G | 1 |
| Güleç, G; Noyan, B | 2 |
| Bordet, R; Corseaux, D; Jude, B; Lund, N; Pu, Q; Robin, E; Vallet, B; Wiel, E | 1 |
| Beierwaltes, WH; Carretero, OA; Dovgan, PS; Nypaver, TJ; Shin, LH | 1 |
| Akita, T; Duan, J; Ikeda, H; Imaizumi, T; Murohara, T; Sasaki, K; Shimada, T; Shintani, S | 1 |
| Carmo, A; Carvalho, AP; Cunha-Vaz, JG; Lopes, MC | 1 |
| Hautala, N; Luodonpää, M; Puhakka, J; Romppanen, H; Ruskoaho, H; Tokola, H; Vuolteenaho, O | 1 |
| Corbett, MA; Dunglison, GF; Gunning, PW; Hardeman, EC; Joya, JE; North, KN; Robinson, CS; Schnell, C; Stewart, AW; Yang, N | 1 |
| Arnold, JM; Feng, Q; Hammond, JR; Lu, X; McCormack, DG; Scott, JA; Shen, J; Stathopulos, PB | 1 |
| Chang, T; Lu, R; Tsai, L | 1 |
| Amico-Roxas, M; Caruso, A; Clementi, G; Cutuli, VM; Fiore, CE; Mangano, NG; Matera, M; Pennisi, P; Prato, A | 1 |
| Thomas, GD; Victor, RG; Zhang, W | 1 |
| Adams, JL; Ames, RS; Badger, AM; Bautsch, W; Bondinell, WE; Cousins, RD; Erhard, KF; Foley, JJ; Hieble, JP; Jurewicz, AJ; Klos, A; Lee, D; McCafferty, G; Osborn, RR; Sarau, HM; Settmacher, B; Sulpizio, AC; Tornetta, MA; Underwood, DC; Ward, KW | 1 |
| Dreshaj, IA; Ferkol, T; Haxhiu, MA; Kelley, TJ; Martin, RJ; Mhanna, MJ; van Heeckeren, AM | 1 |
| Klahr, S | 1 |
| Bahrami, S; Costantino, G; Kozlov, AV; Nohl, H; Redl, H; Sobhian, B | 1 |
| Endo, T; Huang, L; Izumi, K; Kawano, T; Nishitani, H; Ogawa, H; Ogushi, F; Sone, S; Sono, N; Tani, K; Ueno, J | 1 |
| Bukhanevych, OM; Iuz'kiv, MIa; Kotsiuruba, AV; Moĭbenko, OO; Tumanovs'ka, LV | 1 |
| Hebiguchi, T; Imai, H; Kato, T; Komatsuda, A; Mizuno, M; Wakui, H; Yoshino, H | 1 |
| Beger, HG; Kaminishi, M; Mimura, Y; Neuhaus, P; Nussler, AK; Ogawa, T; Tuzuner, E | 1 |
| Akbari, MR; Dehpour, AR; Homayounfar, H; Mani, AR; Nahavandi, A | 1 |
| Inouye, S; Tanaka, J; Yamakawa, T; Yuda, Y | 1 |
| Shishlov, VI; Zaporozhchenko, BS | 1 |
| Nagamine, Y; Rajalakshmi, S; Rao, PM; Roomi, MW; Sarma, DS | 1 |
| Fürst, P | 1 |
| Boelens, PG; Nijveldt, RJ; Prins, HA; Rauwerda, JA; Teerlink, T; van Kemenade, FJ; van Lambalgen, AA; van Leeuwen, PA | 1 |
| Alvarez, M; Bartolí, R; Bertrán, X; Castellá, E; Fernández-Bañares, F; Gassull, MA; Mañé, J; Ojanguren, I | 1 |
| Garvin, JL; Ortiz, PA | 1 |
| Barnes, SE; Weinberg, PD | 1 |
| Kersten, JR; Pagel, PS; Tessmer, JP; Toller, WG; Warltier, DC | 1 |
| Grimble, RF | 1 |
| Babaya, N; Hamada, Y; Ikegami, H; Kawaguchi, Y; Nojima, K; Ogihara, T; Shibata, M; Ueda, H; Yamada, K; Yamato, E | 1 |
| Cheever, AW; Fuentes, JM; Hesse, M; La Flamme, AC; Modolell, M; Pearce, EJ; Schito, M; Wynn, TA | 1 |
| Jokelainen, K; Lalani, EN; Lau, GK; Nanji, AA; Polavarapu, R; Rahemtulla, A; Tipoe, GL | 1 |
| Hayakawa, H; Hirata, Y; Homma, Y; Horie, S; Kawabe, K; Kitamura, T; Minowada, S; Nagai, R; Nagata, D; Nishimatsu, H; Ohta, N; Satonaka, H; Suzuki, E; Takeuchi, T | 1 |
| Hu, H; Liu, Y; Zhu, J | 1 |
| Huang, T; Lin, Y; Zhu, Y | 1 |
| Chen, Z; Jiao, Z; Kuang, Y; Wang, Q; Wu, Z; Yuan, J; Zeng, M; Zhou, H; Zhou, J | 1 |
| Fabry, ME; Nagel, RL; Romero, JR; Suzuka, SM | 1 |
| Kemeny, AA; Major, O; Radatz, MW; Szeifert, GT; Walton, L | 1 |
| Henrion, D; Lévy, BI; Loufrani, L; Matrougui, K | 1 |
| Rajamohan, T; Salil, G | 1 |
| Gotoh, T; Hon, WM; Khoo, HE; Lee, KH; Mori, M; Wei, CL | 1 |
| Dyckes, R; McCullough, RE; Moore, LG; Sillau, AH; White, MM | 1 |
| Brunner, F; Lass, A; Mayer, B; Suessenbacher, A; Wölkart, G | 1 |
| Taiwo, OB; Taylor, BK | 1 |
| Bruins, MJ; Deutz, NE; Hallemeesch, MM; Soeters, PB; van Eijk, HM | 1 |
| Bruins, MJ; Deutz, NE; Lamers, WH; Meijer, AJ; Soeters, PB | 1 |
| Carr, RD; Gotfredsen, CF; Larsen, MO; Rolin, B; Svendsen, O; Wilken, M | 1 |
| Azuma, H; Goto, M; Kihara, K; Masuda, H; Okuno, T; Tsujii, T | 1 |
| Alderton, H; Bancroft, GJ; Gordhan, BG; McAdam, RA; Mizrahi, V; Smith, DA | 1 |
| Akisu, M; Arslanoglu, S; Baka, M; Bayindir, O; Habif, S; Kultursay, N; Ozmen, D; Yalaz, M | 1 |
| Heilig, M; Thorsell, A | 1 |
| Beck-Nielsen, H; Nielsen, TB; Yderstraede, KB | 1 |
| Bruins, MJ; Deutz, NE; Lamers, WH; Soeters, PB | 1 |
| Ishimura, N; Nakaya, Y; Takahashi, A; Takishita, E | 1 |
| Cobben, DC; Deutz, NE; Hallemeesch, MM; Soeters, PB | 1 |
| Paul, V | 1 |
| Formanek, K; Kreil, G | 1 |
| Eaton, RP; Schade, D; Shuck, JM; Shuck, LW; Wachtel, TL | 1 |
| Greenglass, EJ; Martin, JM | 1 |
| Eaton, RP; Oase, R; Schade, DS | 1 |
| Atkinson, AM; Teale, DM | 1 |
| Campbell, KP; Kennedy, CF; Knudson, CM; Litterer, LA; Louis, CF; Mickelson, JR; Rempel, WE; Yang, DI | 1 |
| Boulu, RG; Buisson, A; Plotkine, M | 1 |
| Billiar, TR; Curran, RD; Demetris, AJ; Harbrecht, BG; Ochoa, JB; Simmons, RL; Stadler, J | 1 |
| Collen, D; Gold, HK; Imura, Y; Lesaffre, E; Stassen, JM; Vreys, I | 1 |
| Dawson, DA; Graham, DI; Kusumoto, K; Macrae, IM; McCulloch, J | 1 |
| Helgren, MC; Klabunde, RE | 1 |
| Bankir, L; Bouby, N; Coutaud, C | 1 |
| Finegood, DT; Lewis, JT; Rajotte, RV; Tobin, BL; Tobin, BW | 1 |
| Moncada, S; Rees, DD; Wright, CE | 1 |
| Deshmukh, DR; Mukhopadhyay, A; Sarnaik, AP | 1 |
| Faraci, FM; Heistad, DD | 1 |
| Corna, D; de Gaetano, G; Noris, M; Perico, N; Remuzzi, G; Viganò, G; Zoja, C | 1 |
| Brunson, ME; Risley, GL; Yeatman, TJ | 1 |
| Brezis, M; Dinour, D; Epstein, FH; Heyman, SN; Rosen, S | 1 |
| Brown, JC; Buchan, AM; Campos, RV; Chisholm, CB; Pederson, RA; Russell, JC | 1 |
| Aaen, K; Bock, T; Buschard, K; Josefsen, K; Jørgensen, M | 1 |
| Higashiyama, M; Kambayashi, J; Mori, T; Sakon, M; Tanaka, T; Tsujinaka, T; Yokota, M | 1 |
| Bush, LR; Connolly, TM; Mellott, MJ; York, SJ | 1 |
| Chanarin, I; Deacon, R; Green, R; Lumb, M; Perry, J; Purkiss, P | 1 |
| Fitzgerald, DJ; Fitzgerald, GA | 1 |
| Breddin, HK; Haarmann, W; Krupinski, K; Markwardt, F | 1 |
| Deshmukh, DR; Thomas, PE | 1 |
| Abramson, SB; Weissmann, G | 1 |
| Bhathena, SJ; Hansen, C; Michaelis, OE; Powell, AM; Recant, L; Timmers, KI; Voyles, NR; Wilkins, SD | 1 |
| Flüchter, SH; Rothe, KF; Schorer, R | 1 |
| Rarey, KE | 1 |
| Meyers, WC; Rotolo, FS | 1 |
| Nagai, Y; Nakano, K | 1 |
| Frankel, BJ; Gerich, KE; Gerritsen, GC; Grodsky, GM | 1 |
| Cerasi, E; Gutzeit, A; Karakash, C; Rabinovitch, A; Renold, AE; Stauffacher, W | 1 |
| Madge, DS | 1 |
| Franzblau, C; Hayes, JA; Kagan, HM; Korthy, AL; Snider, GL; Stone, PS | 1 |
| Cameron, DP; Insch, S; Opat, F | 1 |
| Jones, TC; Levy, HL; Madigan, PM; Shih, VE | 1 |
| Akhunova, GD; Atmarin, IP; Bokhon, NN; Borisov, LB | 1 |
| Harvey, JC | 1 |
| Hermann, G | 1 |
| Sun, J; Yan, J; Zeng, Z | 1 |
| Chen, Y; Duan, Y; Han, H; Han, J; Li, X; Liang, Y; Liu, L; Ma, C; Yang, J; Yang, S; Yang, X; Zeng, P; Zhang, W; Zhang, X; Zhu, Y | 1 |
| Bartlett, MS; Fishman, JA; Queener, SF; Roth, RS | 1 |
55 review(s) available for arginine and Disease Models, Animal
| Article | Year |
|---|---|
Activation of arginase II by asymmetric dimethylarginine and homocysteine in hypertensive rats induced by hypoxia: a new model of nitric oxide synthesis regulation in hypertensive processes?
Topics: Animals; Arginase; Arginine; Disease Models, Animal; Homocysteine; Hypertension; Hypoxia; Nitric Oxide; Rats; Rats, Wistar | 2021 |
The contributions of metabolomics in the discovery of new therapeutic targets in Alzheimer's disease.
Topics: Alanine; Alzheimer Disease; Animals; Arginine; Aspartic Acid; Biomarkers; Disease Models, Animal; Glutamic Acid; Humans; Metabolomics; Rats | 2021 |
Interplay between Oxidative Stress and Nutrient Sensing Signaling in the Developmental Origins of Cardiovascular Disease.
Topics: Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Energy Metabolism; Humans; Nitric Oxide; Nutritional Physiological Phenomena; Oxidative Stress; Reactive Oxygen Species; Signal Transduction | 2017 |
Role of NO and other vascular mediators in the etiopathogenesis of necrotizing enterocolitis.
Topics: Age of Onset; Animals; Arginine; Catecholamines; Disease Models, Animal; Dogs; Endothelins; Enterocolitis, Necrotizing; Humans; Indomethacin; Infant, Newborn; Inflammation; Intestines; Microcirculation; Milk, Human; Nitric Oxide; Oxygen Consumption; Rats; Sheep; Vasodilator Agents | 2019 |
The Role of Complement C3a Receptor in Stroke.
Topics: Animals; Arginine; Benzhydryl Compounds; Blood-Brain Barrier; Complement Activation; Complement C3a; Complement Inactivating Agents; Disease Models, Animal; Humans; Immunity, Innate; Mice; Mice, Knockout; Neuroimmunomodulation; Neuroprotective Agents; Receptors, Complement; Stroke; Translational Research, Biomedical | 2019 |
Advanced glycation endproducts in food and their effects on health.
Topics: Absorption; Animals; Arginine; Biological Availability; Chromatography, Liquid; Cooking; Disease Models, Animal; Food; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Mass Spectrometry; Molecular Weight; Odorants; Taste | 2013 |
Recent advances in the investigation of pancreatic inflammation induced by large doses of basic amino acids in rodents.
Topics: Amino Acids, Basic; Animals; Arginine; Disease Models, Animal; Endoplasmic Reticulum Stress; Histological Techniques; Lysine; Mice; Molecular Structure; Ornithine; Oxidative Stress; Pancreas; Pancreatitis; Rats; Regeneration | 2014 |
Increased circulatory asymmetric dimethylarginine and multiple organ failure: bile duct ligation in rat as a model.
Topics: Animals; Arginine; Bile Ducts; Disease Models, Animal; Fibrosis; Ligation; Liver; Liver Cirrhosis; Multiple Organ Failure; Rats | 2014 |
The role of immunomodulators on intestinal barrier homeostasis in experimental models.
Topics: Animals; Arginine; Bifidobacterium; Citrulline; Disease Models, Animal; Epithelial Cells; Fatty Acids, Omega-3; Glutamine; Homeostasis; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Intestinal Mucosa; Lactobacillus; Linoleic Acids, Conjugated; Permeability; Probiotics; Saccharomyces; Tryptophan | 2015 |
Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties.
Topics: Animals; Arginine; Cell-Penetrating Peptides; Disease Models, Animal; Endocytosis; Models, Neurological; Neurons; Neuroprotective Agents; Peptides | 2015 |
Prevention and treatment of cancers by immune modulating nutrients.
Topics: Animals; Arginine; Catechin; Cell Line, Tumor; Diet; Disease Models, Animal; Fatty Acids, Unsaturated; Glutamine; Humans; Isothiocyanates; Lignans; Meta-Analysis as Topic; Micronutrients; Neoplasms; Observational Studies as Topic; Phytochemicals; Polyphenols; Randomized Controlled Trials as Topic; Stilbenes | 2016 |
Peptide Pharmacological Approaches to Treating Traumatic Brain Injury: a Case for Arginine-Rich Peptides.
Topics: Animals; Arginine; Brain Injuries, Traumatic; Disease Models, Animal; Humans; Neuroprotection; Neuroprotective Agents; Peptides | 2017 |
Recent advances in arginine metabolism: roles and regulation of the arginases.
Topics: Animals; Arginase; Arginine; Cytosol; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Mitochondrial Proteins; Muscle, Smooth, Vascular | 2009 |
ADMA and the role of the genes: lessons from genetically modified animals and human gene polymorphisms.
Topics: Animals; Animals, Genetically Modified; Arginine; Disease Models, Animal; Humans; Polymorphism, Genetic | 2009 |
Asymmetric dimethylarginine and reactive oxygen species: unwelcome twin visitors to the cardiovascular and kidney disease tables.
Topics: Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Humans; Kidney Diseases; Rats; Reactive Oxygen Species; Risk Factors | 2012 |
[Methylarginies-induced endothelial dysfunction in chronic kidney disease].
Topics: Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Renal Insufficiency, Chronic; Risk Factors | 2012 |
Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome.
Topics: Acute Coronary Syndrome; Animals; Antithrombins; Arginine; Disease Models, Animal; Drug Evaluation; Heparin; Hirudins; Humans; Peptide Fragments; Percutaneous Coronary Intervention; Pipecolic Acids; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2012 |
Cardiovascular dysfunction of sepsis: a nitric oxide- and l-arginine-deficient state?
Topics: Animals; Arginine; Cardiovascular System; Disease Models, Animal; Hemodynamics; Hemolysin Proteins; Humans; Nitric Oxide; Sepsis | 2003 |
Assessment of anticolitic drugs in the trinitrobenzene sulfonic acid (TNBS) rat model of inflammatory bowel disease.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arginine; Blotting, Western; Colitis; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Inflammatory Bowel Diseases; Injections, Subcutaneous; Instillation, Drug; Male; Models, Animal; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxidase; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2003 |
A novel mechanism for pulmonary arterial hypertension?
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Humans; Hypertension, Pulmonary; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pulmonary Artery; Rats; Vasomotor System | 2003 |
The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
Topics: Administration, Inhalation; Administration, Oral; Animals; Arginine; Dichloroacetic Acid; Disease Models, Animal; Humans; Hypertension, Pulmonary; Models, Biological; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Potassium Channels; Pulmonary Circulation; Purines; Rats; Sildenafil Citrate; Sulfones | 2003 |
[Asymmetrical methylarginine (ADMA) as a cardiovascular risk factor: epidemiological and prospective data].
Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cells, Cultured; Child; Coronary Disease; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Free Radicals; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Nitric Oxide Synthase; Oxidative Stress; Pre-Eclampsia; Pregnancy; Prospective Studies; Rabbits; Regression Analysis; Renal Dialysis; Risk Factors; Stroke | 2004 |
L-arginine-induced experimental pancreatitis.
Topics: Animals; Arginine; Disease Models, Animal; Injections, Intraperitoneal; Pancreatitis, Acute Necrotizing; Regeneration | 2004 |
L-arginine as a therapeutic tool in kidney disease.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Humans; Kidney Diseases; Nitric Oxide; Prognosis; Rats; Renal Circulation; Risk Assessment; Treatment Outcome; Up-Regulation | 2004 |
Endothelial dysfunction in heart failure: mechanisms and therapeutic approaches.
Topics: Animals; Antioxidants; Arginine; Biopterins; Disease Models, Animal; Endothelins; Endothelium, Vascular; Exercise; Genetic Therapy; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Renin-Angiotensin System | 2004 |
[Animal experimental models for acute pancreatitis].
Topics: Acute Disease; Animals; Apoptosis; Arginine; Bacterial Translocation; Bile Acids and Salts; Ceruletide; Disease Models, Animal; Disease Progression; Duodenum; Ethionine; Humans; Ligation; Lipopolysaccharides; Macrophage Activation; Pancreatitis; Severity of Illness Index | 2004 |
[Influence of L-arginine on development of atherosclerosis: what is the therapeutically assured?].
Topics: Animals; Arginine; Arteriosclerosis; Disease Models, Animal; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase | 2005 |
A systematic review of nitric oxide donors and L-arginine in experimental stroke; effects on infarct size and cerebral blood flow.
Topics: Animals; Arginine; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Female; Male; Nitric Oxide Donors; Rabbits; Rats; Time Factors | 2005 |
Mechanisms of homocysteine-induced atherothrombosis.
Topics: Animals; Apolipoproteins E; Apoptosis; Arginine; Atherosclerosis; Coronary Thrombosis; Cysteine; Disease Models, Animal; Endothelium, Vascular; Homocysteine; Humans; Hyperhomocysteinemia; Inflammation; Methionine; Mice; Models, Biological; Nitric Oxide; Oxidative Stress; Oxygen; Phenotype; Signal Transduction | 2005 |
Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models.
Topics: Alcohol Drinking; Allergy and Immunology; Animals; Antioxidants; Apolipoproteins E; Arginine; Arteriosclerosis; Ascorbic Acid; Atherosclerosis; Cell Proliferation; Dietary Fats; Disease Models, Animal; Energy Metabolism; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Genetic Engineering; Genetic Variation; Genomics; Homocysteine; Insulin Resistance; Iron; Magnesium; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Models, Genetic; Phytosterols; Receptors, LDL; Sex Factors; Sodium; Taurine; Vitamin E | 2006 |
Immunomodulation during sepsis in organ transplanted children.
Topics: Age Factors; Animals; Arginine; Child; Cytokines; Data Interpretation, Statistical; Disease Models, Animal; Female; Fish Oils; Graft Rejection; Humans; Immunity, Cellular; Immunologic Factors; Immunosuppression Therapy; Male; Organ Transplantation; Platelet Membrane Glycoproteins; Postoperative Complications; Randomized Controlled Trials as Topic; Receptors, G-Protein-Coupled; Sepsis | 2005 |
ADMA and hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Cardiovascular Diseases; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Homocysteine; Humans; Hyperhomocysteinemia; Nitric Oxide; Nitric Oxide Synthase Type III; Risk Factors; Superoxides; Vasodilation | 2005 |
Pharmacotherapies and their influence on asymmetric dimethylargine (ADMA).
Topics: Amidohydrolases; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biomarkers; Cardiovascular Diseases; Clinical Trials as Topic; Disease Models, Animal; Drug Evaluation, Preclinical; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperhomocysteinemia; Nitric Oxide; Nitric Oxide Synthase; Protein-Arginine N-Methyltransferases; Renal Insufficiency | 2005 |
The arginine-arginase balance in asthma and lung inflammation.
Topics: Animals; Arginase; Arginine; Asthma; Disease Models, Animal; Gene Expression Regulation; Humans; Lung; Mice; Nitric Oxide Synthase; Pneumonia; RNA, Messenger | 2006 |
[Coronary allograft vasculopathy: pathophysiological interaction between the immune system, infections and metabolic syndrome].
Topics: Animals; Arginine; Clinical Trials as Topic; Coronary Disease; Cytomegalovirus Infections; Disease Models, Animal; Endothelium, Vascular; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Hypolipidemic Agents; Immunosuppression Therapy; Immunosuppressive Agents; Metabolic Syndrome; Quality of Life; Risk Assessment; Risk Factors; Rodentia; Stents; Time Factors | 2007 |
Arginase and pulmonary diseases.
Topics: Animals; Arginase; Arginine; Asthma; Cystic Fibrosis; Disease Models, Animal; Humans; Hypertension, Pulmonary; Lung; Lung Diseases; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Pulmonary Disease, Chronic Obstructive; Pulmonary Fibrosis; Urea | 2008 |
Depression and cardiovascular disease: role of nitric oxide.
Topics: Animals; Arginine; Cardiovascular Diseases; Depression; Disease Models, Animal; Humans; Nitric Oxide; Risk Factors; Signal Transduction | 2008 |
Selective inhibition of the activity of inducible nitric oxide synthase in septic shock.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Humans; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Shock, Septic; Thiourea | 1995 |
The L-arginine/nitric oxide pathway--biological properties and therapeutic applications.
Topics: Animals; Arginine; Child; Disease Models, Animal; Female; Humans; Neoplasms; Nitric Oxide; Sepsis; Wounds and Injuries | 1994 |
Dietary L-arginine in renal disease.
Topics: Animals; Arginine; Disease Models, Animal; Food, Fortified; Kidney Diseases; Kidney Glomerulus; Nitric Oxide; Rats | 1996 |
Salt-sensitive hypertension: lessons from animal models.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Humans; Hypertension; Nitric Oxide; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 1996 |
The role of nitric oxide in cardiac surgery.
Topics: Animals; Arginine; Cardiac Surgical Procedures; Disease Models, Animal; Heart Diseases; Humans; Hypertension, Pulmonary; Hypoxia; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophil Activation; Nitric Oxide; Nitric Oxide Synthase; Vasodilation | 1997 |
Enhancement of nitric oxide synthesis by L-arginine supplementation in renal disease: is it good or bad?
Topics: Animals; Arginine; Dietary Supplements; Disease Models, Animal; Humans; Kidney Diseases; Nitric Oxide; Reference Values; Treatment Outcome | 1997 |
Effect of argatroban, a selective thrombin inhibitor, on animal models of cerebral thrombosis.
Topics: Acute Disease; Animals; Anticoagulants; Antithrombin III Deficiency; Antithrombins; Arginine; Disease Models, Animal; Extracorporeal Circulation; Intracranial Embolism and Thrombosis; Pipecolic Acids; Rats; Sulfonamides | 1997 |
Chronic nitric oxide inhibition model six years on.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Heart; Hemodynamics; Humans; Hypertension, Renovascular; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 1998 |
Can nitric oxide production be modulated by altering L-arginine levels?
Topics: Animals; Arginine; Bacteremia; Disease Models, Animal; Endothelium, Vascular; Humans; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Sheep; Shock, Septic; Up-Regulation; Vasodilation | 1999 |
The role of nitric oxide in hypertension and renal disease progression.
Topics: Animals; Arginine; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Humans; Hypertension; Kidney; Kidney Diseases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Renal Circulation | 2001 |
[Influence of amino acids on pancreatic functional activity].
Topics: Amylases; Animals; Arginine; Disease Models, Animal; Humans; Methionine; Pancreatitis; Rats; Rats, Wistar | 2000 |
Conditionally indispensable amino acids (glutamine, cyst(e)ine, tyrosine, arginine, ornithine, taurine) in enteral feeding and the dipeptide concept.
Topics: Amino Acids, Essential; Animals; Arginine; Cysteine; Disease Models, Animal; Enteral Nutrition; Glutamine; Humans; Intestinal Mucosa; Ornithine; Taurine; Treatment Outcome; Tyrosine | 2000 |
Intrarenal transport and vasoactive substances in hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biological Transport; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY | 2001 |
Nutritional modulation of immune function.
Topics: Animals; Arginine; Cytokines; Dietary Fats, Unsaturated; Disease Models, Animal; Fatty Acids, Omega-3; Glutamine; Humans; Immunity; Inflammation; Nucleotides; Nutritional Physiological Phenomena; T-Lymphocytes | 2001 |
Brain neuropeptide Y (NPY) in stress and alcohol dependence.
Topics: Alcoholism; Animals; Anxiety; Arginine; Behavior, Animal; Benzazepines; Brain; Depression; Disease Models, Animal; DNA-Binding Proteins; Gene Expression; Genetic Heterogeneity; Humans; Neuropeptide Y; Receptors, Neuropeptide Y; Stress, Physiological | 2002 |
Complement split products and the pathogenesis of SLE.
Topics: Anaphylatoxins; Animals; Antibodies; Arginine; Biomarkers; Central Nervous System Diseases; Complement Activation; Complement C3; Complement C3a; Complement C5; Complement C5a; Complement Pathway, Alternative; Disease Models, Animal; Female; Humans; Lupus Erythematosus, Systemic; Neutropenia; Peptides; Pregnancy; Rabbits | 1988 |
[Experimental allergic encephalomyelitis antigen (author's transl)].
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Cerebrospinal Fluid; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Guinea Pigs; Haplorhini; Immunity, Maternally-Acquired; Methylation; Multiple Sclerosis; Myelin Basic Protein; Myelin Sheath; Peptides; Proteins; Rats; Species Specificity | 1974 |
DNA topoisomerase II inhibitors.
Topics: Amsacrine; Antineoplastic Agents; Carcinogens; Disease Models, Animal; Etoposide; Evidence-Based Medicine; Humans; Intestinal Absorption; Mitoxantrone; Neoplasms; Nucleic Acid Synthesis Inhibitors; Research Design; Risk Factors; Teniposide; Tissue Distribution; Topoisomerase II Inhibitors | 2000 |
6 trial(s) available for arginine and Disease Models, Animal
| Article | Year |
|---|---|
An engineered
Topics: Ammonia; Animals; Arginine; Biosynthetic Pathways; Disease Models, Animal; Escherichia coli; Feces; Female; Genetic Engineering; Healthy Volunteers; Humans; Hyperammonemia; Macaca fascicularis; Male; Mice; Nitrates; Stress, Physiological; Survival Analysis | 2019 |
Nutritional Interventions that Slow the Age-Associated Decline in Renal Function in a Canine Geriatric Model for Elderly Humans.
Topics: Absorptiometry, Photon; Aged; Aging; Animals; Arginine; Biomarkers; Body Weight; Carnitine; Cross-Sectional Studies; Diet; Dietary Proteins; Dietary Supplements; Disease Models, Animal; Dogs; Female; Fish Oils; Fruit; Geriatric Assessment; Glomerular Filtration Rate; Humans; Kidney; Male; Thioctic Acid; Vegetables | 2016 |
[Role of lipid peroxidation in hepatic ischemia-reperfusion injury and effect of L-Arginine].
Topics: Adult; Aged; Animals; Arginine; Disease Models, Animal; Female; Humans; Lipid Peroxidation; Liver Diseases; Male; Middle Aged; Postoperative Period; Rabbits; Reperfusion Injury | 2003 |
Decrease in sensitisation rate and intestinal anaphylactic response after nitric oxide synthase inhibition in a food hypersensitivity model.
Topics: Animals; Arginine; Colon; Disease Models, Animal; Guinea Pigs; Immunization; Immunoglobulin A; Immunoglobulin E; Intestinal Mucosa; Lactoglobulins; Male; Milk; Milk Hypersensitivity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Permeability | 1996 |
Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: a double-blind, randomized placebo-controlled study.
Topics: Animals; Antineoplastic Agents; Arginine; Cachexia; Diet; Dietary Supplements; Disease Models, Animal; Disease-Free Survival; Docosahexaenoic Acids; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doxorubicin; Eicosapentaenoic Acid; Fatty Acids; Fish Oils; Lactic Acid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Survival Analysis | 2000 |
Effect of argatroban on trinitrobenzene sulfonic acid-induced colitis.
Topics: Analysis of Variance; Animals; Antithrombins; Arginine; Blood Coagulation Tests; Colitis; Disease Models, Animal; Heparin; Immunoenzyme Techniques; Infusion Pumps, Implantable; Leukotriene B4; Male; Nitrobenzenes; Peroxidase; Pipecolic Acids; Rats; Rats, Wistar; Sulfonamides; Sulfonic Acids | 2000 |
1070 other study(ies) available for arginine and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy.
Topics: Animals; Arginine; Calpain; Disease Models, Animal; Glycine; Heart Failure; HEK293 Cells; Humans; Male; Membrane Proteins; Mice; Muscle Proteins; Mutagenesis, Site-Directed; Myocytes, Cardiac; Proteolysis; Signal Transduction; Threonine; Transfection | 2021 |
Astaxanthin engages the l-arginine/NO/cGMP/KATP channel signaling pathway toward antinociceptive effects.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Glyburide; KATP Channels; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Signal Transduction; Sildenafil Citrate; Xanthophylls | 2021 |
Ghee Butter from Bovine Colostrum Reduces Inflammation in the Mouse Model of Acute Pancreatitis with Potential Involvement of Free Fatty Acid Receptors.
Topics: Amylases; Animals; Anti-Inflammatory Agents; Arginine; Cattle; Colostrum; Cytokines; Disease Models, Animal; Fatty Acids, Nonesterified; Female; Ghee; Inflammation; Lipase; Lung; Male; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis; Peroxidase; Pregnancy; Receptors, G-Protein-Coupled | 2021 |
Epithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis.
Topics: Adenoma; Adenomatous Polyposis Coli; Amino Acids; Animals; Arginine; Argininosuccinate Synthase; Carcinogenesis; Cell Line, Tumor; Diet; Disease Models, Animal; Epithelial Cells; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Intestines; Liver; Mice, Inbred C57BL; Mice, Knockout; Mutation; Organoids; Regeneration; RNA, Messenger; Up-Regulation | 2021 |
Arginine metabolism and nitric oxide turnover in the ZSF1 animal model for heart failure with preserved ejection fraction.
Topics: Animals; Arginase; Arginine; Disease Models, Animal; Female; Heart; Heart Failure; Kidney; Male; Metabolic Syndrome; Myocardium; Nitric Oxide; Obesity; Rats; Stroke Volume; Thinness; Ventricular Function, Left | 2021 |
Respiratory Syncytial Virus Matrix Protein-Chromatin Association Is Key to Transcriptional Inhibition in Infected Cells.
Topics: Animals; Arginine; Cell Line; Cell Nucleus; Chlorocebus aethiops; Chromatin; Disease Models, Animal; DNA, Viral; Humans; Lysine; Mice, Inbred BALB C; Models, Biological; Mutant Proteins; Mutation; Protein Binding; Protein Domains; Respiratory Syncytial Virus Infections; Respiratory Syncytial Virus, Human; RNA, Viral; Transcription, Genetic; Vero Cells; Viral Matrix Proteins; Viremia | 2021 |
Synergistic effect between quinpirole and L-NAME as well as sulpiride and L-arginine on the modulation of anxiety and memory processes in the 6-OHDA mouse model of Parkinson's disease: An isobologram analysis.
Topics: Adrenergic Agents; Animals; Anxiety; Arginine; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Therapy, Combination; Enzyme Inhibitors; Male; Memory; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidopamine; Parkinson Disease; Quinpirole; Receptors, Dopamine D2; Sulpiride | 2021 |
Chymase as a Novel Therapeutic Target in Acute Pancreatitis.
Topics: Animals; Arginine; Chymases; Cricetinae; Disease Models, Animal; Leukocyte Count; Lipase; Male; Matrix Metalloproteinase 9; Neutrophils; Pancreatitis; RNA, Messenger; Signal Transduction; Sulfonamides; Survival Rate; Thiophenes; Treatment Outcome; Tumor Necrosis Factor-alpha | 2021 |
Restraint stress potentiates neuropeptide Y-mediated impairment on spatial memory in rats.
Topics: Animals; Arginine; Behavior, Animal; Benzazepines; Disease Models, Animal; Male; Memory Disorders; Neuropeptide Y; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Restraint, Physical; Spatial Memory; Stress, Psychological | 2022 |
Beneficial effects of citrulline enteral administration on sepsis-induced T cell mitochondrial dysfunction.
Topics: Animals; Arginine; Biological Availability; Citrulline; Cytokines; Disease Models, Animal; Female; Immune Tolerance; Immunosuppression Therapy; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mitochondria; Myeloid-Derived Suppressor Cells; Sepsis; T-Lymphocytes; T-Lymphocytes, Regulatory | 2022 |
Use of sildenafil and L-arginine in an experimental rat model for the prevention of neonatal necrotizing enterocolitis.
Topics: Animals; Animals, Newborn; Arginine; Disease Models, Animal; Enterocolitis, Necrotizing; Humans; Infant, Newborn; Infant, Newborn, Diseases; Ki-67 Antigen; Rats; Sildenafil Citrate | 2022 |
Pirfenidone ameliorates chronic pancreatitis in mouse models through immune and cytokine modulation.
Topics: Acute Disease; Animals; Arginine; Ceruletide; Collagen; Cytokines; Disease Models, Animal; Fibrosis; Humans; Mice; Pancreatitis, Chronic; Pyridones | 2022 |
Electroacupuncture at BL15 attenuates chronic fatigue syndrome by downregulating iNOS/NO signaling in C57BL/6 mice.
Topics: Acupuncture Points; Animals; Arginine; Disease Models, Animal; Electroacupuncture; Fatigue Syndrome, Chronic; Humans; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II | 2023 |
Tau-binding protein PRMT8 facilitates vacuole degeneration in the brain.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Arginine; Brain; Carrier Proteins; Disease Models, Animal; Mice; Mice, Transgenic; Protein-Arginine N-Methyltransferases; Proteomics; tau Proteins; Vacuoles; Vimentin | 2022 |
USP25 Deficiency Exacerbates Acute Pancreatitis via Up-Regulating TBK1-NF-κB Signaling in Macrophages.
Topics: Acute Disease; Animals; Arginine; Ceruletide; Choline; Cytokines; Deubiquitinating Enzymes; Disease Models, Animal; Ethionine; Interferon Type I; Lung Injury; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; Pancreatitis; Signal Transduction; Ubiquitin Thiolesterase; Ubiquitin-Specific Proteases | 2022 |
Citrullination is linked to reduced Ca
Topics: Actins; Animals; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Citrullination; Citrulline; Disease Models, Animal; Heart Failure; Hydrolases; Mice; Protein-Arginine Deiminases; Tumor Necrosis Factor-alpha | 2022 |
Huang Qin Decoction inhibits the initiation of experimental colitis associated carcinogenesis by controlling the PAD4 dependent NETs.
Topics: Animals; Arginine; Carcinogenesis; Chromatin; Colitis; Colitis, Ulcerative; Disease Models, Animal; Extracellular Traps; Humans; Inflammation; Ki-67 Antigen; Mice; Mice, Inbred C57BL; Occludin; Scutellaria baicalensis; Tumor Necrosis Factor-alpha | 2022 |
Comparative Analysis of Host Metabolic Alterations in Murine Malaria Models with Uncomplicated or Severe Malaria.
Topics: Animals; Arginine; Bile Acids and Salts; Bile Pigments; Disease Models, Animal; Hippurates; Histidine; Hormones; Humans; Malaria, Cerebral; Mice; Ornithine; Phenylalanine; Plasmodium berghei; Sphingolipids; Valine | 2022 |
Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Female; Gonadotropins; Hydrolases; Infertility; Male; Mice; Mice, Knockout; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Testosterone | 2022 |
Cognitive and arginine metabolic correlates of temporal dysfunction in the MIA rat model of schizophrenia risk.
Topics: Animals; Arginine; Cognition; Cognitive Dysfunction; Disease Models, Animal; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Schizophrenia | 2023 |
Systemic Bile Acids Affect the Severity of Acute Pancreatitis in Mice Depending on Their Hydrophobicity and the Disease Pathogenesis.
Topics: Acute Disease; Animals; Arginine; Bile Acids and Salts; Ceruletide; Cholecystokinin; Disease Models, Animal; Hydrophobic and Hydrophilic Interactions; Mice; Pancreas; Pancreatitis | 2022 |
Enterococci enhance Clostridioides difficile pathogenesis.
Topics: Animals; Anti-Bacterial Agents; Arginine; Clostridioides difficile; Disease Models, Animal; Disease Susceptibility; Drug Resistance, Bacterial; Enterococcus; Gastrointestinal Microbiome; Humans; Intestines; Leucine; Mice; Microbial Interactions; Ornithine; Virulence | 2022 |
Development of a novel ex vivo organ culture system to improve preservation methods of regenerative tissues.
Topics: Animals; Arginine; Cold Shock Proteins and Peptides; Cold Temperature; Disease Models, Animal; Organ Culture Techniques | 2023 |
Barley Leaf Ameliorates
Topics: Animals; Arginine; Citrobacter rodentium; Colitis; Colon; Disease Models, Animal; Hordeum; Mice; Mice, Inbred C57BL | 2023 |
Anti-inflammatory activity of curcumin in a model of L-arginine-induced acute pancreatitis in rats.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Curcumin; Disease Models, Animal; Inflammation; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley | 2023 |
Effect of adropin on seizure activity in rats with penicillin-induced epilepsy.
Topics: Animals; Anticonvulsants; Arginine; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Penicillins; Rats; Rats, Wistar; Seizures | 2023 |
Arginine Dysregulation and Myocardial Dysfunction in a Mouse Model and Children with Chronic Kidney Disease.
Topics: Animals; Arginase; Arginine; Citrulline; Disease Models, Animal; Mice; Renal Dialysis; Renal Insufficiency, Chronic | 2023 |
Evaluation of circulating miR-216a and miR-217 as biomarkers of pancreatic damage in the L-arginine-induced acute pancreatitis mouse model.
Topics: Acute Disease; Amylases; Animals; Arginine; Biomarkers; Disease Models, Animal; Lipase; Mice; MicroRNAs; Necrosis; Pancreas; Pancreatitis | 2023 |
Exploiting Arginine Auxotrophy with Pegylated Arginine Deiminase (ADI-PEG20) to Sensitize Pancreatic Cancer to Radiotherapy via Metabolic Dysregulation.
Topics: Animals; Arginine; Cell Line, Tumor; Disease Models, Animal; Humans; Hydrolases; Mice; Pancreatic Neoplasms; Polyethylene Glycols | 2019 |
Involvement of l-arginine-nitric oxide pathway in the antidepressant and memory promoting effects of morin in mice.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Depression; Disease Models, Animal; Flavonoids; Injections, Intraperitoneal; Male; Memory; Memory and Learning Tests; Methylene Blue; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Signal Transduction; Swimming | 2019 |
Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency.
Topics: Ammonia; Animals; Arginase; Arginine; Codon; Disease Models, Animal; Glutamine; Hyperammonemia; Hyperargininemia; Lipids; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Nanoparticles; RNA, Messenger; Urea | 2019 |
Multi-Omics Studies Demonstrate
Topics: Animals; Arginine; Chemokines; Citric Acid Cycle; Cytokines; Dendritic Cells; Disease Models, Animal; Glycolysis; Macrophages; Male; Metabolomics; Mice; Mice, Inbred BALB C; Multivariate Analysis; Phosphorylation; Toxoplasma; Toxoplasmosis, Animal; Transcriptome; Up-Regulation | 2019 |
NLRP3 Inflammasome Regulates Development of Systemic Inflammatory Response and Compensatory Anti-Inflammatory Response Syndromes in Mice With Acute Pancreatitis.
Topics: Acinar Cells; Adaptive Immunity; Animals; Arginine; Cells, Cultured; Ceruletide; Cytokines; Disease Models, Animal; Furans; Heterocyclic Compounds, 4 or More Rings; Humans; Indenes; Inflammasomes; Injections, Intraperitoneal; Interleukin-18; Macrophages; Mice; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Pancreas; Pancreatitis; Primary Cell Culture; Sulfonamides; Sulfones; Systemic Inflammatory Response Syndrome; Th2 Cells | 2020 |
Melatonin rescued methotrexate-induced spatial deficit and hyperhomocysteinemia and increased asymmetric dimethylarginine in plasma and dorsal hippocampus in developing rats.
Topics: Animals; Animals, Newborn; Antimetabolites, Antineoplastic; Arginine; Disease Models, Animal; Hippocampus; Hyperhomocysteinemia; Male; Maze Learning; Melatonin; Methotrexate; Rats; Rats, Sprague-Dawley; Spatial Behavior | 2020 |
Chrm3 protects against acinar cell necrosis by stabilizing caspase-8 expression in severe acute pancreatitis mice model.
Topics: Acinar Cells; Animals; Arginine; Caspase 8; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Pancreatitis; Protective Agents; Receptor, Muscarinic M3; Transcriptome | 2020 |
Blueberry anthocyanin‑enriched extract ameliorates transverse aortic constriction‑induced myocardial dysfunction via the DDAH1/ADMA/NO signaling pathway in mice.
Topics: Amidohydrolases; Animals; Anthocyanins; Aortic Valve Stenosis; Apoptosis; Arginine; Blueberry Plants; Cardiovascular Diseases; Disease Models, Animal; Gene Expression Regulation; Humans; Mice; Myocytes, Cardiac; Nitric Oxide; Oxidative Stress; Plant Extracts; Signal Transduction | 2020 |
Intracortical Administration of the Complement C3 Receptor Antagonist Trifluoroacetate Modulates Microglia Reaction after Brain Injury.
Topics: Animals; Arginine; Benzhydryl Compounds; Disease Models, Animal; Mice; Microglia; Neurons; Phagocytosis; Receptors, Complement; Recovery of Function; Stroke; Trifluoroacetic Acid | 2019 |
Irisin attenuates intestinal injury, oxidative and endoplasmic reticulum stress in mice with L-arginine-induced acute pancreatitis.
Topics: Animals; Apoptosis; Arginine; Disease Models, Animal; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Fibronectins; Interleukin-6; Intestines; Liver; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Pancreas; Pancreatitis; Tumor Necrosis Factor-alpha | 2019 |
Asymmetric dimethylation and citrullination in the LEW.1AR1-iddm rat, an animal model of human type 1 diabetes, and effects of anti-TCR/anti-TNF-α antibody-based therapy.
Topics: Animals; Antibodies; Arginine; Blood Glucose; Citrullination; Diabetes Mellitus, Type 1; Disease Models, Animal; DNA Methylation; Humans; Male; Pancreas; Rats; Rats, Inbred Lew; Receptors, Antigen, T-Cell, alpha-beta; Spleen; Tumor Necrosis Factor-alpha | 2020 |
Plasma-derived exosomes contribute to pancreatitis-associated lung injury by triggering NLRP3-dependent pyroptosis in alveolar macrophages.
Topics: Acute Lung Injury; Animals; Arginine; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Exosomes; Humans; Inflammasomes; Macrophages, Alveolar; Male; Mice; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Pancreatitis; Pyroptosis | 2020 |
Arginine metabolic control of airway inflammation.
Topics: Adult; Animals; Arginase; Arginine; Asthma; Cytokines; Disease Models, Animal; Female; Genotype; Humans; Inflammation; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Polymorphism, Single Nucleotide | 2020 |
Signaling pathways that regulate Trypanosoma cruzi infection and immune response.
Topics: Adaptive Immunity; Animals; Antigens, Protozoan; Arginine; Caspase 1; Chagas Disease; Disease Models, Animal; Disease Vectors; Host-Parasite Interactions; Humans; Immunity, Innate; Indoleamine-Pyrrole 2,3,-Dioxygenase; Macrophage Activation; Macrophages; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Aryl Hydrocarbon; Signal Transduction; Toll-Like Receptors; Triatoma; Trypanosoma cruzi; Tryptophan | 2020 |
Anticonvulsant Activity of Essential Oil From Leaves of Zhumeria majdae (Rech.) in Mice: The Role of GABA
Topics: Animals; Anticonvulsants; Arginine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; GABAergic Neurons; gamma-Aminobutyric Acid; Humans; Male; Mice; Nitric Oxide; Oils, Volatile; Pentylenetetrazole; Plant Leaves; Plant Oils; Salvia; Seizures; Synaptic Transmission | 2020 |
Generation of mouse model of TGFBI-R124C corneal dystrophy using CRISPR/Cas9-mediated homology-directed repair.
Topics: Amino Acid Substitution; Animals; Arginine; Corneal Dystrophies, Hereditary; Corneal Stroma; CRISPR-Cas Systems; Cysteine; Disease Models, Animal; Extracellular Matrix Proteins; Female; Heterozygote; Homozygote; Humans; Male; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Mutation; Recombinational DNA Repair; Transforming Growth Factor beta | 2020 |
Involvement of Satellite Cell Activation via Nitric Oxide Signaling in Ectopic Orofacial Hypersensitivity.
Topics: Animals; Arginine; Disease Models, Animal; Glial Fibrillary Acidic Protein; Humans; Hyperalgesia; Mandibular Nerve; Mandibular Nerve Injuries; Neuralgia; Neuroglia; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Satellite Cells, Skeletal Muscle; Signal Transduction; Trigeminal Ganglion; Trigeminal Nerve Injuries | 2020 |
The possible protective effect of Nano-Selenium on the endocrine and exocrine pancreatic functions in a rat model of acute pancreatitis.
Topics: Acute Disease; Administration, Oral; Animals; Arginine; Disease Models, Animal; Male; Nanoparticles; Oxidative Stress; Pancreas; Pancreatitis; Protective Agents; Rats; Rats, Wistar; Selenium | 2020 |
Analysis of L-arginine:glycine amidinotransferase-, creatine- and homoarginine-dependent gene regulation in the murine heart.
Topics: Amidinotransferases; Animals; Arginine; Connective Tissue Growth Factor; Creatine; Desmocollins; Disease Models, Animal; Energy Metabolism; Fibrinogen; Gene Expression Regulation; Genetic Association Studies; Homoarginine; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Mice, Transgenic; Myocardial Infarction; Myocardium; Potassium Channels; Transcriptome | 2020 |
Defective arginine metabolism impairs mitochondrial homeostasis in Caenorhabditiselegans.
Topics: Adenosine Triphosphate; Animals; Arginase; Arginine; Caenorhabditis elegans; Cytosol; Disease Models, Animal; Homeostasis; Humans; Hyperargininemia; Mitochondria; Mutation | 2020 |
Maternal supplementation with citrulline or arginine during gestation impacts fetal amino acid availability in a model of intrauterine growth restriction (IUGR).
Topics: Amino Acids; Animals; Arginine; Citrulline; Diet, Protein-Restricted; Dietary Supplements; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Fetus; Maternal Nutritional Physiological Phenomena; Pregnancy; Prenatal Care; Rats | 2020 |
PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids.
Topics: Animals; Arginine; Bacterial Proteins; Base Sequence; Chromatin Immunoprecipitation; Disease Models, Animal; Fatty Acids; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genes, Bacterial; Ligands; Mice; Models, Molecular; Mutation; Palmitic Acid; Palmitoyl Coenzyme A; Phosphatidylcholines; Pneumonia, Bacterial; Promoter Regions, Genetic; Pseudomonas aeruginosa; Transcriptome; Virulence | 2020 |
Montelukast, a cysteinyl leukotriene receptor antagonist, exerts local antinociception in animal model of pain through the L-arginine/nitric oxide/cyclic GMP/K
Topics: Acetates; Analgesia; Analgesics; Animals; Arginine; Behavior, Animal; Cyclic GMP; Cyclopropanes; Disease Models, Animal; KATP Channels; Leukotriene Antagonists; Male; Nitric Oxide; Nociceptive Pain; PPAR gamma; Quinolines; Rats, Wistar; Signal Transduction; Sulfides | 2021 |
Arginine is a disease modifier for polyQ disease models that stabilizes polyQ protein conformation.
Topics: Animals; Arginine; Caenorhabditis elegans; Disease Models, Animal; Drosophila; Female; Heredodegenerative Disorders, Nervous System; Huntington Disease; Male; Mice; Mice, Inbred Strains; Molecular Chaperones; Peptides; Protein Aggregation, Pathological; Protein Conformation; Protein Folding; Spinocerebellar Ataxias | 2020 |
Cardiac sympathetic activation circumvents high-dose beta blocker therapy in part through release of neuropeptide Y.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Arginine; Disease Models, Animal; Neuropeptide Y; Receptors, Neuropeptide Y; Sus scrofa; Sympathetic Nervous System; Tachycardia, Ventricular | 2020 |
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Topics: 3T3 Cells; Animals; Arginase; Arginine; Autoantigens; CCAAT-Enhancer-Binding Protein-beta; Cell Line; Dendritic Cells; Disease Models, Animal; HaCaT Cells; HEK293 Cells; Humans; Interleukin-17; Keratinocytes; Macaca fascicularis; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Phosphoprotein Phosphatases; Phosphorylation; Polyamines; Psoriasis; RNA; Skin; Toll-Like Receptor 7 | 2020 |
A role for NPY-NPY2R signaling in albuminuric kidney disease.
Topics: Albuminuria; Animals; Arginine; Benzazepines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Doxorubicin; Humans; Insulin; Kidney Diseases; Kidney Glomerulus; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neuropeptide Y; Podocytes; Proteomics; Receptors, Neuropeptide Y; Signal Transduction | 2020 |
Affective dimensions of pain and region -specific involvement of nitric oxide in the development of empathic hyperalgesia.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Empathy; Female; Hyperalgesia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociception; Pain; Rats, Wistar | 2020 |
Properties of virulence emergence of Leishmania infantum isolates from Phlebotomus perniciosus collected during the human leishmaniosis outbreak in Madrid, Spain. Hepatic histopathology and immunological parameters as virulence markers in the mouse model.
Topics: Animals; Antibodies, Protozoan; Arginine; Biomarkers; Cytokines; Disease Models, Animal; Disease Outbreaks; Female; Humans; Immunity, Humoral; Leishmania infantum; Leishmaniasis, Visceral; Liver; Mice; Mice, Inbred BALB C; Phagocytes; Phlebotomus; Phylogeny; Seasons; Spain; Virulence | 2021 |
Histone H4R3 symmetric di-methylation by Prmt5 protects against cardiac hypertrophy via regulation of Filip1L/β-catenin.
Topics: Animals; Arginine; beta Catenin; Cells, Cultured; Disease Models, Animal; Epigenesis, Genetic; Histones; Hypertrophy, Left Ventricular; Male; Methylation; Mice, Inbred C57BL; Myocytes, Cardiac; Protein-Arginine N-Methyltransferases; Rats, Sprague-Dawley; Signal Transduction; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Enhanced dimethylarginine degradation improves coronary flow reserve and exercise tolerance in Duchenne muscular dystrophy carrier mice.
Topics: Amidohydrolases; Animals; Arginine; Cardiomyopathies; Coronary Circulation; Disease Models, Animal; Exercise Tolerance; Female; Heterozygote; Male; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, Transgenic; Muscular Dystrophy, Duchenne; Myocardium; Necrosis; Quadriceps Muscle; Ventricular Function, Left | 2020 |
Renal asymmetric dimethylarginine inhibits fibrosis.
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Fibronectins; Fibrosis; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred C57BL; Renal Insufficiency, Chronic; Ureteral Obstruction | 2020 |
Kynurenines link chronic inflammation to functional decline and physical frailty.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Chronic Disease; Cytokines; Disease Models, Animal; Female; Frail Elderly; Humans; Inflammation; Interleukin-10; Kynurenine; Male; Mice, Inbred C57BL; Middle Aged; Neuromuscular Junction; Serotonin; Tryptophan; Walking Speed; Young Adult | 2020 |
Effects of a herbal formulation, KGC3P, and its individual component, nepetin, on coal fly dust-induced airway inflammation.
Topics: Animals; Arginine; Asthma; Bronchoalveolar Lavage Fluid; Coal; Coal Ash; Cytokines; Disease Models, Animal; Flavones; Herbal Medicine; Lung; Mice; Signal Transduction | 2020 |
Modulation of Nitric Oxide Bioavailability Attenuates Ischemia-Reperfusion Injury in Type II Diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reperfusion Injury; Skin; Surgical Flaps | 2021 |
Intestinal resection affects whole-body arginine synthesis in neonatal piglets.
Topics: Animals; Animals, Newborn; Arginine; Disease Models, Animal; Intestines; Male; Swine | 2021 |
Pentadecapeptide BPC 157 counteracts L-NAME-induced catalepsy. BPC 157, L-NAME, L-arginine, NO-relation, in the suited rat acute and chronic models resembling 'positive-like' symptoms of schizophrenia.
Topics: Amphetamine; Animals; Apomorphine; Arginine; Behavior, Animal; Catalepsy; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agents; Enzyme Inhibitors; Haloperidol; Male; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Proteins; Rats; Rats, Wistar; Schizophrenia | 2021 |
Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; ATPases Associated with Diverse Cellular Activities; C9orf72 Protein; Disease Models, Animal; DNA Repeat Expansion; Drosophila melanogaster; Drosophila Proteins; Frontotemporal Dementia; HEK293 Cells; Humans; Metalloendopeptidases; Mitochondria; Mitochondrial Proteins; Protein Biosynthesis; Proteome; Receptors, Notch; Ribosomes; Signal Transduction | 2020 |
Vinpocetine ameliorates L-arginine induced acute pancreatitis via Sirt1/Nrf2/TNF pathway and inhibition of oxidative stress, inflammation, and apoptosis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arginine; Biomarkers; Disease Models, Animal; Inflammation Mediators; Male; NF-E2-Related Factor 2; Oxidative Stress; Pancreas; Pancreatitis; Rats, Wistar; Signal Transduction; Sirtuin 1; Tumor Necrosis Factor-alpha; Vinca Alkaloids | 2021 |
The restorative effect of apocynin and catalase in l-arginine induced hypotension on normotensive subjects - the role of oxidative stress.
Topics: Acetophenones; Animals; Antioxidants; Arginine; Blood Pressure; Catalase; Disease Models, Animal; Hypotension; Kidney; Male; NADPH Oxidase 4; Oxidative Stress; Pulse Wave Analysis; Rats; Rats, Inbred WKY | 2020 |
Gene delivery corrects N-acetylglutamate synthase deficiency and enables insights in the physiological impact of L-arginine activation of N-acetylglutamate synthase.
Topics: Amino-Acid N-Acetyltransferase; Animals; Arginine; Citrulline; Dependovirus; Disease Models, Animal; Gene Transfer Techniques; Glutamates; Humans; Hyperammonemia; Mice; Mice, Knockout; Mutant Proteins; Urea; Urea Cycle Disorders, Inborn | 2021 |
Nitric oxide and bone: The phoenix rises again.
Topics: Animals; Arginine; Argininosuccinate Lyase; Disease Models, Animal; Mice; Nitric Oxide | 2021 |
Photobiomodulation therapy was more effective than photobiomodulation plus arginine on accelerating wound healing in an animal model of delayed healing wound.
Topics: Animals; Arginine; Disease Models, Animal; Low-Level Light Therapy; Rats; Vascular Endothelial Growth Factor A; Wound Healing | 2022 |
C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Cell Nucleus; Cytoplasm; Dipeptides; Disease Models, Animal; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Frontotemporal Dementia; Gene Knockdown Techniques; Heterogeneous-Nuclear Ribonucleoprotein Group F-H; Humans; Neurons; Nuclear Localization Signals; RNA; RNA Processing, Post-Transcriptional; RNA-Binding Proteins | 2021 |
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6.
Topics: Amino Acid Sequence; Animals; Arginine; Axonal Transport; Brain-Derived Neurotrophic Factor; Cell Death; Disease Models, Animal; Drosophila melanogaster; Epigenesis, Genetic; Genes, Reporter; Green Fluorescent Proteins; HEK293 Cells; Humans; Huntingtin Protein; Huntington Disease; Methylation; Mice; Mice, Transgenic; Neuromuscular Junction; Neurons; Nuclear Proteins; Protein Isoforms; Protein-Arginine N-Methyltransferases; Transport Vesicles | 2021 |
The first knock-in rat model for glutaric aciduria type I allows further insights into pathophysiology in brain and periphery.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Arginine; Brain; Brain Diseases, Metabolic; Creatine; Disease Models, Animal; Gene Knock-In Techniques; Gliosis; Glutaryl-CoA Dehydrogenase; Humans; Lysine; Metabolism, Inborn Errors; Rats | 2021 |
Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity.
Topics: Adipocytes; Adipose Tissue, Brown; Adult; Animals; Arginine; Biopsy; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Energy Metabolism; Female; Humans; Male; Mice; Middle Aged; Obesity; Primary Cell Culture; Receptors, Neuropeptide Y; Thermogenesis | 2021 |
Capillary Electrophoresis-High Resolution Mass Spectrometry for Measuring In Vivo Arginine Isotope Incorporation in Alzheimer's Disease Mouse Models.
Topics: Alzheimer Disease; Animals; Apolipoprotein E4; Arginine; Brain; Carbon Isotopes; Disease Models, Animal; Electrophoresis, Capillary; Female; Humans; Isotope Labeling; Male; Mass Spectrometry; Mice, Transgenic; Nitric Oxide Synthase Type II; Nitrogen Isotopes; Proof of Concept Study | 2021 |
Promotion of Anti-Tuberculosis Macrophage Activity by L-Arginine in the Absence of Nitric Oxide.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Cell Survival; Dietary Supplements; Disease Models, Animal; Humans; Macrophage Activation; Macrophages; Mice; Mice, Knockout; Mycobacterium tuberculosis; Nitric Oxide; Primary Cell Culture; RAW 264.7 Cells; Tuberculosis | 2021 |
Targeting HMGB1/TLR4/NF-κB signaling pathway by protocatechuic acid protects against l-arginine induced acute pancreatitis and multiple organs injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Disease Models, Animal; HMGB1 Protein; Humans; Hydroxybenzoates; Kidney; Liver; Male; Multiple Organ Failure; NF-kappa B; Pancreas; Pancreatitis; Rats; Signal Transduction; Toll-Like Receptor 4 | 2021 |
NEI-01-Induced Arginine Deprivation Has Potent Activity Against Acute Myeloid Leukemia Cells Both
Topics: Animals; Arginine; Disease Models, Animal; Humans; Hypothalamic Hormones; Leukemia, Myeloid, Acute; Mice; Peptide Fragments | 2021 |
Highbush Blueberry (
Topics: Animals; Arginine; Biomarkers; Blood Glucose; Blueberry Plants; Dietary Sucrose; Disease Models, Animal; Hypoglycemic Agents; Hypolipidemic Agents; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Plant Extracts; Plant Leaves; Rats, Wistar; Triglycerides | 2021 |
Early-life febrile seizures worsen adult phenotypes in Scn1a mutants.
Topics: Action Potentials; Age Factors; Animals; Animals, Newborn; Arginine; Convulsants; Disease Models, Animal; Disease Progression; Exploratory Behavior; Female; Flurothyl; Hippocampus; Histidine; Humans; Hyperthermia, Induced; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Phenotype; Reaction Time; Recognition, Psychology; Seizures, Febrile | 2017 |
Negligible effect of eNOS palmitoylation on fatty acid regulation of contraction in ventricular myocytes from healthy and hypertensive rats.
Topics: Animals; Arginine; Disease Models, Animal; Fatty Acids; Heart Ventricles; Hypertension; Male; Myocardium; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxygen Consumption; Palmitic Acid; Rats; Rats, Sprague-Dawley | 2017 |
Effects of maternal immune activation on brain arginine metabolism of postnatal day 2 rat offspring.
Topics: Animals; Arginine; Brain; Cluster Analysis; Disease Models, Animal; Female; Male; Pregnancy; Pregnancy Complications, Infectious; Rats, Sprague-Dawley | 2018 |
The pathogenic LRRK2 R1441C mutation induces specific deficits modeling the prodromal phase of Parkinson's disease in the mouse.
Topics: Animals; Arginine; Cysteine; Disease Models, Animal; Exploratory Behavior; Gait; Genotype; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Transgenic; Motor Activity; Parkinson Disease; Point Mutation; Prodromal Symptoms; Recognition, Psychology; Smell; Swimming; Synaptophysin; Synaptotagmin I; Tyrosine 3-Monooxygenase | 2017 |
Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.
Topics: Aging; Aldosterone; Amidohydrolases; Animals; Arginine; Cell Line; Creatinine; Diabetes Mellitus, Experimental; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Gene Knockout Techniques; Humans; Kidney Diseases; Kidney Tubules, Proximal; Mice | 2017 |
Protective effect against brain tissues oxidative damage as a possible mechanism for beneficial effects of L-arginine on lipopolysaccharide induced memory impairment in rats.
Topics: Animals; Antioxidants; Arginine; Avoidance Learning; Behavior, Animal; Biomarkers; Catalase; Disease Models, Animal; Hippocampus; Lipopolysaccharides; Male; Malondialdehyde; Memory; Memory Disorders; Nitric Oxide; Oxidative Stress; Rats, Wistar; Reaction Time; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha | 2018 |
Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis.
Topics: Acute Disease; Analgesics, Opioid; Animals; Arginine; Ceruletide; Disease Models, Animal; Disease Progression; Fatty Acids, Monounsaturated; Mice; Mice, Knockout; Morphine; Pancreas; Pancreatitis; Severity of Illness Index; Time Factors | 2018 |
Uptake and metabolism of arginine impact Plasmodium development in the liver.
Topics: Animals; Arginine; Cationic Amino Acid Transporter 2; Cell Line; Disease Models, Animal; Gene Expression Regulation; Hepatocytes; Host-Pathogen Interactions; Humans; Liver; Malaria; Mice; Mice, Knockout; Plasmodium; Plasmodium berghei | 2017 |
Transdermally administered proline-arginine-rich host defense peptides show systemic efficacy in a lethal mouse bacteremia model.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Administration, Cutaneous; Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Arginine; Bacteremia; Bacterial Load; Carbapenems; Colistin; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Ear; Humans; Mice; Proline; Skin; Survival Analysis | 2017 |
High-Throughput Metabolomics for Discovering Potential Metabolite Biomarkers and Metabolic Mechanism from the APPswe/PS1dE9 Transgenic Model of Alzheimer's Disease.
Topics: Alzheimer Disease; Animals; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Cognitive Dysfunction; Dicarboxylic Acids; Disease Models, Animal; Early Diagnosis; Glucuronic Acid; Glyoxylates; Humans; Male; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multivariate Analysis; Pentoses; Proline; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Starch; Sucrose; Tryptophan | 2017 |
Endogenous nitric oxide inhibits spinal NMDA receptor activity and pain hypersensitivity induced by nerve injury.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Central Nervous System Agents; Cyclic GMP; Disease Models, Animal; Ethylmaleimide; Excitatory Amino Acid Antagonists; Hot Temperature; Hyperalgesia; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type I; Posterior Horn Cells; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase; Spinal Nerves; Tissue Culture Techniques; Touch | 2017 |
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.
Topics: Amidohydrolases; Animals; Arginine; Atrial Natriuretic Factor; Disease Models, Animal; Fibrosis; Genetic Predisposition to Disease; Hypertrophy, Left Ventricular; Male; Mice, Knockout; Myocytes, Cardiac; Nitric Oxide; Phenotype; Signal Transduction; Tyrosine; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2017 |
CitH3: a reliable blood biomarker for diagnosis and treatment of endotoxic shock.
Topics: 2-Naphthylamine; Animals; Arginine; Biomarkers; Citrullination; Diagnostic Tests, Routine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Extracellular Traps; Histones; Immunologic Factors; Mice; Protein Processing, Post-Translational; Sensitivity and Specificity; Shock, Septic; Time Factors; Treatment Outcome | 2017 |
Celecoxib-induced gastrointestinal, liver and brain lesions in rats, counteraction by BPC 157 or L-arginine, aggravation by L-NAME.
Topics: Animals; Anti-Ulcer Agents; Antidotes; Arginine; Brain; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Proteins; Rats; Rats, Wistar; Stomach; Stomach Ulcer | 2017 |
Remote Ischemic Preconditioning Decreases the Magnitude of Hepatic Ischemia-Reperfusion Injury on a Swine Model of Supraceliac Aortic Cross-Clamping.
Topics: Animals; Aorta; Arginine; Biomarkers; C-Reactive Protein; Constriction; Disease Models, Animal; Ferritins; Interleukin-6; Ischemic Preconditioning; Liver; Liver Diseases; Male; Reperfusion Injury; Splanchnic Circulation; Sus scrofa; Time Factors; Tumor Necrosis Factor-alpha | 2018 |
Protein arginylation targets alpha synuclein, facilitates normal brain health, and prevents neurodegeneration.
Topics: alpha-Synuclein; Amino Acid Sequence; Aminoacyltransferases; Animals; Arginine; Brain; Cells, Cultured; Disease Models, Animal; Humans; Mass Spectrometry; Mice; Mice, Knockout; Models, Biological; Neurodegenerative Diseases; Neurons; Peptides; Protein Aggregates; Protein Aggregation, Pathological; Protein Processing, Post-Translational; Proteolysis; Recombinant Proteins; Substrate Specificity | 2017 |
Systemic Evaluation of Vascular Dysfunction by High-Resolution Sonography in an N
Topics: Animals; Arginine; Blood Flow Velocity; Carotid Artery, Common; Disease Models, Animal; Female; Femoral Artery; Mice; Mice, Inbred C57BL; Placental Circulation; Pre-Eclampsia; Pregnancy; Reproducibility of Results; Ultrasonography, Prenatal; Umbilical Arteries; Vascular Diseases | 2018 |
Protective effect of chlorogenic acid on the inflammatory damage of pancreas and lung in mice with l-arginine-induced pancreatitis.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Chlorogenic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Lung; Lung Injury; Macrophage Migration-Inhibitory Factors; Male; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis; Severity of Illness Index | 2017 |
Sub-therapeutic doses of fluvastatin and valsartan are more effective than therapeutic doses in providing beneficial cardiovascular pleiotropic effects in rats: A proof of concept study.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Cholesterol; Coronary Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Heart; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Indoles; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Receptor, Endothelin A; Time Factors; Valsartan; Vasodilation | 2017 |
Endotoxin Preconditioning Reprograms S1 Tubules and Macrophages to Protect the Kidney.
Topics: Animals; Arginine; Bacterial Load; Cellular Reprogramming; Chimera; Cytokines; Disease Models, Animal; Kidney Tubules, Proximal; Lipopolysaccharides; Macrophages; Male; Metabolome; Mice; Mice, Knockout; Phagocytosis; Sepsis; Succinates; Survival Rate; Toll-Like Receptor 4; Transcriptome | 2018 |
Time-Dependent Production of Endothelium-Related Biomarkers is Affected Differently in Hemorrhagic and Septic Shocks.
Topics: Animals; Antioxidants; Arginine; Biomarkers; Blood Pressure; Disease Models, Animal; Endothelial Cells; Hydrogen Sulfide; Male; Nitric Oxide; Rats, Wistar; Resuscitation; Shock, Hemorrhagic; Shock, Septic; Time Factors | 2018 |
Enhanced antitumor efficacy of arginine modified amphiphilic nanoparticles co-delivering doxorubicin and iSur-pDNA via the multiple synergistic effect.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Apoptosis; Arginine; Cell Line, Tumor; Cell Proliferation; Chitosan; Disease Models, Animal; Doxorubicin; Drug Delivery Systems; Drug Synergism; Female; Humans; Inhibitor of Apoptosis Proteins; Mice; Nanoparticles; RNA, Small Interfering; Surface-Active Agents; Survivin | 2018 |
Identification of a Novel Subset of Myeloid-Derived Suppressor Cells During Chronic Staphylococcal Infection That Resembles Immature Eosinophils.
Topics: Adoptive Transfer; Animals; Arginine; CD11b Antigen; CD4-Positive T-Lymphocytes; Cell Proliferation; Cytokines; Disease Models, Animal; Eosinophils; Female; Gene Expression; Immune Tolerance; Interleukin-5 Receptor alpha Subunit; Kidney; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells; Nitric Oxide; Phenotype; Receptors, CCR3; Spleen; Staphylococcal Infections; Staphylococcus aureus; T-Lymphocytes; T-Lymphocytes, Regulatory | 2017 |
Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans.
Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabditis elegans; Cell Nucleus; Dipeptides; Disease Models, Animal; DNA Repeat Expansion; Frontotemporal Dementia; Gene Expression Regulation; Genes, Regulator; Motor Neurons; Mutation | 2017 |
Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.
Topics: Acute Disease; Animals; Arginine; Autophagy; Bile Acids and Salts; Calcium Signaling; Ceruletide; Choline Deficiency; Cyclophilins; Disease Models, Animal; Endoplasmic Reticulum Stress; Ethionine; Genetic Predisposition to Disease; Humans; Lipid Metabolism; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Proton-Translocating ATPases; Pancreas; Pancreatitis; Peptidyl-Prolyl Isomerase F; Phenotype; Rats; Time Factors; Trehalose | 2018 |
Elevated Levels of ADMA Are Associated with Lower DDAH2 and Higher PRMT1 in LPS-Induced Endometritis Rats.
Topics: Amidohydrolases; Animals; Arginine; Dinoprost; Disease Models, Animal; Down-Regulation; Endometriosis; Female; Interleukin-6; Lipopolysaccharides; Peroxidase; Protein-Arginine N-Methyltransferases; Rats, Wistar; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Up-Regulation; Uterus | 2018 |
Disruption of the Opal Stop Codon Attenuates Chikungunya Virus-Induced Arthritis and Pathology.
Topics: Animals; Arginine; Arthritis; Chikungunya Fever; Chikungunya virus; Codon, Terminator; Disease Models, Animal; Mice; Mutation; Viral Nonstructural Proteins; Virulence Factors; Virus Replication | 2017 |
Dachaihu decoction ameliorates pancreatic fibrosis by inhibiting macrophage infiltration in chronic pancreatitis.
Topics: Animals; Arginine; Chemokine CCL2; Chemokine CCL3; Disease Models, Animal; Drugs, Chinese Herbal; Enzyme-Linked Immunosorbent Assay; Fibronectins; Fibrosis; Humans; Interleukin-6; Macrophages; Medicine, Chinese Traditional; Mice; Pancreas; Pancreatitis, Chronic; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2017 |
Modulation of the anticonvulsant effect of swim stress by agmatine.
Topics: Agmatine; Analgesics, Opioid; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction; Swimming | 2018 |
Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss.
Topics: Adoptive Transfer; Amylases; Animals; Antibodies, Neutralizing; Arginine; Cell Survival; Disease Models, Animal; Hydrogen; Interleukin-10; Interleukin-2 Receptor alpha Subunit; Lipase; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Pancreas; Pancreatitis, Chronic; Protective Agents; Reactive Oxygen Species; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha | 2017 |
Venlafaxine Attenuates the Development of Morphine Tolerance and Dependence: Role of L-Arginine/Nitric Oxide/cGMP Pathway.
Topics: Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Brain; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence; Nitric Oxide; Nociceptive Pain; Signal Transduction; Time Factors; Venlafaxine Hydrochloride | 2018 |
Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function.
Topics: Animals; Arginine; Disease Models, Animal; Glutathione Peroxidase; Heart Diseases; Mice; Mice, Knockout; Platelet Aggregation; Reactive Oxygen Species; Renal Insufficiency, Chronic; Thrombosis; Ventricular Dysfunction, Left | 2018 |
L-arginine supplementation reduces mortality and improves disease outcome in mice infected with Trypanosoma cruzi.
Topics: Animals; Arginine; Chagas Disease; Disease Models, Animal; Electrocardiography; Mice, Inbred BALB C; Myocardium; Parasite Load; Plasma; Survival Analysis; Treatment Outcome; Trypanosoma cruzi | 2018 |
Stable gastric pentadecapeptide BPC 157 in the treatment of colitis and ischemia and reperfusion in rats: New insights.
Topics: Animals; Anti-Ulcer Agents; Arginine; Colitis; Collateral Circulation; Colon; Disease Models, Animal; Humans; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Peptide Fragments; Proteins; Rats; Rats, Wistar; Reperfusion Injury | 2017 |
A novel mouse model carrying a human cytoplasmic dynein mutation shows motor behavior deficits consistent with Charcot-Marie-Tooth type 2O disease.
Topics: Amino Acid Substitution; Animals; Animals, Genetically Modified; Arginine; Charcot-Marie-Tooth Disease; Cytoplasmic Dyneins; Disease Models, Animal; Gene Knock-In Techniques; Histidine; Humans; Longitudinal Studies; Male; Mice; Mutant Proteins; Mutation, Missense | 2018 |
HIF1-alpha Regulates Acinar Cell Function and Response to Injury in Mouse Pancreas.
Topics: Acinar Cells; Acute Disease; Animals; Arginine; Ceruletide; Disease Models, Animal; Homeostasis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Pancreas; Pancreas, Exocrine; Pancreatitis; Vascular Endothelial Growth Factor A | 2018 |
Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia.
Topics: Activin Receptors; Activins; Anemia, Diamond-Blackfan; Animals; Arginine; Benzamides; Benzhydryl Compounds; Complement C3a; Dioxoles; Disease Models, Animal; Humans; Immunity, Innate; Interferons; K562 Cells; Receptor, Transforming Growth Factor-beta Type I; Ribosomal Proteins; RNA, Small Interfering; Toll-Like Receptor 3; Transforming Growth Factor beta; Tumor Suppressor Protein p53; Up-Regulation; Zebrafish; Zebrafish Proteins | 2018 |
Anti-inflammatory and Antioxidant Effects of Captopril Compared to Methylprednisolone in L-Arginine-Induced Acute Pancreatitis.
Topics: Acute Disease; alpha-Amylases; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Captopril; Cytoprotection; Disease Models, Animal; Glutathione; Lipase; Male; Methylprednisolone; Nitric Oxide; Nitric Oxide Synthase Type II; Pancreas; Pancreatitis; Peroxidase; Rats, Wistar; Renin-Angiotensin System; Signal Transduction; Tumor Necrosis Factor-alpha | 2018 |
Disruption of Renal Arginine Metabolism Promotes Kidney Injury in Hepatorenal Syndrome in Mice.
Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Biopsy, Needle; Disease Models, Animal; Disease Progression; Hepatorenal Syndrome; Humans; Immunohistochemistry; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Random Allocation; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Survival Rate | 2018 |
MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.
Topics: Amino Acid Substitution; Animals; Arginine; Axons; Charcot-Marie-Tooth Disease; Disease Models, Animal; Drug Design; Glutamine; GTP Phosphohydrolases; Humans; Methionine; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Diseases; Mitochondrial Proteins; Oligopeptides; Phosphorylation; Protein Kinases; Sciatic Nerve; Small Molecule Libraries; Threonine | 2018 |
Arginase upregulation and eNOS uncoupling contribute to impaired endothelium-dependent vasodilation in a rat model of intrauterine growth restriction.
Topics: Age Factors; Animal Nutritional Physiological Phenomena; Animals; Aorta, Thoracic; Arginase; Arginine; Diet, Protein-Restricted; Disease Models, Animal; Endothelium, Vascular; Female; Fetal Growth Retardation; Hypertension; Male; Maternal Nutritional Physiological Phenomena; Nitric Oxide; Nitric Oxide Synthase Type III; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Signal Transduction; Time Factors; Up-Regulation; Vasodilation | 2018 |
Altered plasma arginine metabolome precedes behavioural and brain arginine metabolomic profile changes in the APPswe/PS1ΔE9 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arginine; Behavior, Animal; Brain; Disease Models, Animal; Female; Humans; Male; Maze Learning; Metabolome; Mice; Mice, Transgenic; Presenilin-1; Spatial Memory | 2018 |
Arginine administration increases circulating endothelial progenitor cells and attenuates tissue injury in a mouse model of hind limb ischemia/reperfusion.
Topics: Animals; Arginine; Cytokines; Disease Models, Animal; Endothelial Progenitor Cells; Hindlimb; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Reperfusion Injury | 2018 |
Inhibition of peptidylarginine deiminase alleviates LPS-induced pulmonary dysfunction and improves survival in a mouse model of lethal endotoxemia.
Topics: 2-Naphthylamine; Acute Lung Injury; Animals; Arginine; Citrullination; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Endotoxemia; Extracellular Traps; Histones; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; Lung; Mice; Mice, Inbred C57BL; Microvessels; Neutrophils; Permeability; Protein-Arginine Deiminases; Treatment Outcome | 2018 |
Metabolomic analysis of cholestatic liver damage in mice.
Topics: Animals; Arginine; Bile Acids and Salts; Biomarkers; Cholangitis, Sclerosing; Cholestasis; Chromatography, Liquid; Disease Models, Animal; Glutathione; Liver Cirrhosis, Biliary; Male; Mass Spectrometry; Metabolomics; Mice, Inbred C57BL; Phospholipids | 2018 |
FGF23 impairs peripheral microvascular function in renal failure.
Topics: Animals; Arginine; Cells, Cultured; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Endothelial Cells; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Gracilis Muscle; Humans; Kidney; Male; Mice, Inbred C57BL; Microcirculation; Microvessels; Renal Insufficiency, Chronic; Signal Transduction; Vascular Resistance; Vasodilation; Vasodilator Agents | 2018 |
Arginase overexpression in neurons and its effect on traumatic brain injury.
Topics: Animals; Arginase; Arginine; Brain Injuries, Traumatic; Cell Line; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Humans; Mice; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Thy-1 Antigens | 2018 |
Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis,
Topics: Animals; Arginine; Disease Models, Animal; Humans; Hydroxamic Acids; Kinetics; Lung Diseases; Macrocyclic Compounds; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Mice; Mice, Transgenic; Molecular Imaging; Molecular Structure; Radiopharmaceuticals; Technetium | 2018 |
Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.
Topics: Animals; Arginine; Ceruletide; Chymotrypsin; Disease Models, Animal; Enzyme Activation; Enzyme Stability; Female; Male; Mice, Inbred C57BL; Mice, Knockout; Pancreas; Pancreatitis; Proteolysis; Severity of Illness Index; Trypsin | 2018 |
Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma.
Topics: Animals; Arginine; Biotinylation; Brain Neoplasms; Child; Chromatin; Disease Models, Animal; Embryonic Stem Cells; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycine; Histones; Humans; Mice; Mutation; Point Mutation; Protein Binding; Sequence Analysis, RNA; Transgenes | 2018 |
Evaluation of anticoagulant agents for the treatment of human metapneumovirus infection in mice.
Topics: Animals; Anticoagulants; Arginine; Disease Models, Animal; Heparin; Metapneumovirus; Mice; Paramyxoviridae Infections; Pipecolic Acids; Sulfonamides; Survival Analysis; Treatment Outcome; Viral Load; Virus Replication; Warfarin | 2018 |
ADMA, homocysteine and redox status improvement affected by 7-nitroindazole in spontaneously hypertensive rats.
Topics: Animals; Aorta; Arginine; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Heart Ventricles; Homocysteine; Hypertension; Indazoles; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidation-Reduction; Rats, Inbred SHR | 2018 |
Ex Vivo Enteroids Recapitulate In Vivo Citrulline Production in Mice.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Intestines; Liver; Male; Mice; Mice, Inbred ICR; Mice, Mutant Strains; Mutation; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Tissue Culture Techniques; Urea | 2018 |
Augmentation of the Enhanced Permeability and Retention Effect with Nitric Oxide-Generating Agents Improves the Therapeutic Effects of Nanomedicines.
Topics: Animals; Antineoplastic Agents; Arginine; Disease Models, Animal; Doxorubicin; Female; Hydroxyurea; Macromolecular Substances; Male; Mice; Nanomedicine; Nanoparticles; Neoplasms; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Permeability; Rats, Sprague-Dawley | 2018 |
The Effect of Chemerin on Cardiac Parameters and Gene Expressions in Isolated Perfused Rat Heart
Topics: Animals; Arginine; Cardiac Output; Chemokines; Disease Models, Animal; Heart; Intercellular Signaling Peptides and Proteins; Myocardial Contraction; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2019 |
Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis.
Topics: Animals; Arginine; Argininosuccinate Synthase; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Energy Metabolism; Female; Genetic Predisposition to Disease; Humans; Kidney; Male; Metabolomics; Mice, Knockout; Phenotype; Polycystic Kidney, Autosomal Dominant; Receptors, Cell Surface; Signal Transduction; TRPP Cation Channels | 2018 |
An autoimmune disease variant of IgG1 modulates B cell activation and differentiation.
Topics: Amino Acid Substitution; Animals; Arginine; Autoantibodies; Autoimmunity; B-Lymphocytes; Cell Differentiation; Disease Models, Animal; Gene Knock-In Techniques; Glycine; GRB2 Adaptor Protein; Heterozygote; Humans; Immunoglobulin G; Immunological Synapses; Lupus Erythematosus, Systemic; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Phosphorylation; Plasma Cells; Signal Transduction | 2018 |
Attenuation of glutamatergic and nitrergic system contributes to the antidepressant-like effect induced by capsazepine in the forced swimming test.
Topics: 2-Amino-5-phosphonovalerate; Animals; Antidepressive Agents; Apomorphine; Arginine; Capsaicin; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Enzyme Inhibitors; Exploratory Behavior; Glutamic Acid; Male; Microinjections; Nitric Oxide; Nitroprusside; Rats; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Swimming | 2019 |
Arginine methylation of FOXP3 is crucial for the suppressive function of regulatory T cells.
Topics: Animals; Arginine; Biomarkers; Cell Line; Cytokines; Disease Models, Animal; Fluorescent Antibody Technique; Forkhead Transcription Factors; Gene Expression Profiling; Graft vs Host Disease; Humans; Kaplan-Meier Estimate; Male; Methylation; Mice; Mutation; Protein Processing, Post-Translational; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory | 2019 |
(‑)Epigallocatechin‑3‑gallate attenuates anesthesia‑induced memory deficit in young mice via modulation of nitric oxide expression.
Topics: Anesthesia; Animals; Antioxidants; Apoptosis; Arginine; Biomarkers; Catechin; Disease Models, Animal; Indazoles; Male; Memory; Memory Disorders; Mice; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Oxidative Stress | 2018 |
Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function.
Topics: Actins; Adult; Animals; Arginine; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glycolysis; Heart Failure; Heart Ventricles; Humans; Lysine; Male; Mice; Middle Aged; Myosins; Pyruvaldehyde; Sarcomeres; Single-Cell Analysis | 2018 |
Renoprotective Effects of Antroquinonol in Rats with N
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Antrodia; Arginine; Arterioles; Biological Products; Biomarkers; Blood Pressure; Disease Models, Animal; Hypertension; Inflammation; Kidney; Kidney Diseases; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats, Wistar; Ubiquinone | 2018 |
Role of arginine deiminase in thymic atrophy during experimental Streptococcus pyogenes infection.
Topics: Animals; Apoptosis; Arginine; Atrophy; Bacterial Proteins; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Humans; Hydrolases; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mutagenesis, Site-Directed; Mutation; Streptococcal Infections; Streptococcus pyogenes; T-Lymphocytes; Thymus Gland; Virulence | 2019 |
Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics.
Topics: Animals; Arginase; Arginine; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Models, Animal; Energy Metabolism; Female; Humans; Lipid Metabolism; Lipids; Metabolomics; Mice; Mice, Inbred BALB C; Neoplasm Staging; Polyamines; Tandem Mass Spectrometry | 2018 |
Chronic intermittent hypoxia-mediated renal sympathetic nerve activation in hypertension and cardiovascular disease.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensins; Animals; Arginine; Cardiovascular Diseases; Deoxyguanosine; Disease Models, Animal; Humans; Hypertension; Hypoxia; Kidney; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Oxidative Stress; Sympathectomy; Sympathetic Nervous System | 2018 |
Bypassing major venous occlusion and duodenal lesions in rats, and therapy with the stable gastric pentadecapeptide BPC 157, L-NAME and L-arginine.
Topics: Animals; Arginine; Colitis, Ischemic; Collateral Circulation; Disease Models, Animal; Duodenum; Humans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Peptide Fragments; Protective Agents; Proteins; Random Allocation; Rats; Rats, Wistar; Treatment Outcome; Veins; Venous Thrombosis | 2018 |
Altered brain arginine metabolism in a mouse model of tauopathy.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Humans; Male; Mice; Mice, Transgenic; tau Proteins; Tauopathies | 2019 |
Counteraction of perforated cecum lesions in rats: Effects of pentadecapeptide BPC 157, L-NAME and L-arginine.
Topics: Animals; Anti-Ulcer Agents; Arginine; Cecum; Disease Models, Animal; Drug Therapy, Combination; Humans; Intestinal Perforation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Proteins; Rats; Rats, Wistar; Treatment Outcome; Wound Healing | 2018 |
Development of a stent capable of the controlled release of basic fibroblast growth factor and argatroban to treat cerebral aneurysms: In vitro experiment and evaluation in a rabbit aneurysm model.
Topics: Animals; Arginine; Delayed-Action Preparations; Disease Models, Animal; Drug-Eluting Stents; Female; Fibroblast Growth Factor 2; Intracranial Aneurysm; Pipecolic Acids; Rabbits; Sulfonamides | 2019 |
Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak.
Topics: Animals; Arginase; Arginine; Blood-Brain Barrier; Citrulline; Dietary Supplements; Disease Models, Animal; Free Radical Scavengers; Humans; Malaria, Cerebral; Mice; Mice, Inbred C57BL; Nitric Oxide; Plasmodium berghei; Superoxides; Urea | 2019 |
Combination of L-Arginine and L-Norvaline protects against pulmonary fibrosis progression induced by bleomycin in mice.
Topics: Administration, Oral; Animals; Arginine; Bleomycin; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Intraepithelial Lymphocytes; Lung; Male; Mice; Pulmonary Fibrosis; T-Lymphocytes, Regulatory; Th17 Cells; Valine | 2019 |
piRNA-DQ722010 contributes to prostate hyperplasia of the male offspring mice after the maternal exposed to microcystin-leucine arginine.
Topics: Animals; Arginine; Argonaute Proteins; Bacterial Toxins; Cell Line, Tumor; Cyanobacteria Toxins; Disease Models, Animal; Drinking Water; Epithelial Cells; Female; Fresh Water; Hyperplasia; Leucine; Male; Marine Toxins; Maternal Exposure; Mice; Mice, Inbred BALB C; Microarray Analysis; Microcystins; Phosphatidylinositol 3-Kinases; Pregnancy; Prostate; Prostatic Neoplasms; Protein Isoforms; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Water Pollution | 2019 |
Hepatic Lysosomal iNOS Activity Impairs Autophagy in Obesity.
Topics: Animals; Arginine; Autophagy; Cells, Cultured; Diet, High-Fat; Disease Models, Animal; Hepatocytes; Insulin Resistance; Liver; Lysosomes; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrosative Stress; Obesity | 2019 |
Molecular evidence of tissue remodeling in an animal model of heart failure.
Topics: Animals; Aorta; Arginine; Biomarkers; Disease Models, Animal; Extracellular Matrix; Fibrosis; Fistula; Heart; Heart Failure; Immunohistochemistry; Male; Matrix Metalloproteinase 9; Myocardium; Rats; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1 | 2019 |
Arginine Starvation and Docetaxel Induce c-Myc-Driven hENT1 Surface Expression to Overcome Gemcitabine Resistance in ASS1-Negative Tumors.
Topics: Animals; Arginine; Argininosuccinate Synthase; Cell Line, Tumor; Cell Membrane; Deoxycytidine; Disease Models, Animal; Docetaxel; Equilibrative Nucleoside Transporter 1; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Models, Biological; Neoplasms; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-myc; Xenograft Model Antitumor Assays | 2019 |
Reduced endothelial nitric oxide synthase activation contributes to cardiovascular injury during chronic kidney disease progression.
Topics: Acute Kidney Injury; Animals; Arginine; Cardiomegaly; Disease Models, Animal; Disease Progression; Down-Regulation; Enzyme Activation; Fibrosis; HSP90 Heat-Shock Proteins; Male; Myocardium; Natriuretic Peptide, Brain; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats, Wistar; Renal Insufficiency, Chronic; Threonine; Time Factors | 2019 |
N-Carbamylglutamate and l-Arginine Promote Intestinal Absorption of Amino Acids by Regulating the mTOR Signaling Pathway and Amino Acid and Peptide Transporters in Suckling Lambs with Intrauterine Growth Restriction.
Topics: Amino Acid Transport Systems; Amino Acids; Animals; Animals, Newborn; Arginine; Disease Models, Animal; Female; Fetal Growth Retardation; Glutamates; Intestinal Absorption; Membrane Transport Proteins; Nitric Oxide; Pregnancy; RNA, Messenger; Sheep, Domestic; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
MYC-Driven Small-Cell Lung Cancer is Metabolically Distinct and Vulnerable to Arginine Depletion.
Topics: Animals; Arginine; Cell Line, Tumor; Disease Models, Animal; Energy Metabolism; Humans; Lung Neoplasms; Metabolic Networks and Pathways; Mice; Mice, Transgenic; Models, Biological; Proto-Oncogene Proteins c-myc; Signal Transduction; Small Cell Lung Carcinoma; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2019 |
Protein arginine methyltranferase-1 induces ER stress and epithelial-mesenchymal transition in renal tubular epithelial cells and contributes to diabetic nephropathy.
Topics: Activating Transcription Factor 6; Animals; Apoptosis; Arginine; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Endoplasmic Reticulum Stress; Endoribonucleases; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Gene Expression Regulation; Glucose; Humans; Kidney Tubules; Mice; Mice, Knockout; Protein Serine-Threonine Kinases; Protein-Arginine N-Methyltransferases; Repressor Proteins | 2019 |
Neuroprotective effect of L-arginine in a neonatal rat model of hypoxic-ischemia.
Topics: Animals; Animals, Newborn; Apoptosis; Arginine; Corpus Striatum; Disease Models, Animal; Hippocampus; Hypoxia-Ischemia, Brain; In Situ Nick-End Labeling; Neuroprotective Agents; Rats; Rats, Wistar | 2019 |
l-arginine minimizes immunosuppression and prothrombin time and enhances the genotoxicity of 5-fluorouracil in rats.
Topics: Animals; Arginine; Disease Models, Animal; DNA Damage; Female; Fluorouracil; Immunosuppression Therapy; Prothrombin Time; Rats; Rats, Wistar | 2019 |
l-Proline protects mice challenged by Klebsiella pneumoniae bacteremia.
Topics: Animals; Anti-Bacterial Agents; Arginine; Bacteremia; Biomarkers; Disease Models, Animal; Female; Klebsiella Infections; Klebsiella pneumoniae; Metabolomics; Mice; Mice, Inbred C57BL; Proline | 2021 |
Pharmacological inhibition of NPY receptors illustrates dissociable features of experimental colitis in the mouse DSS model: Implications for preclinical evaluation of efficacy in an inflammatory bowel disease model.
Topics: Animals; Arginine; Benzazepines; Body Weight; Colitis; Dextran Sulfate; Disease Models, Animal; Female; Humans; Inflammatory Bowel Diseases; Male; Mice; Mice, Inbred C57BL; Receptors, Neuropeptide Y | 2019 |
Protective role of pirfenidone against experimentally-induced pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Arginine; Cytokines; Disease Models, Animal; Male; Mice; Oxidative Stress; Pancreas; Pancreatic Function Tests; Pancreatitis; Pyridones | 2019 |
Effects of salvianolic acid A on plasma and tissue dimethylarginine levels in a rat model of myocardial infarction.
Topics: Amidohydrolases; Animals; Arginine; Caffeic Acids; Chromatography, High Pressure Liquid; Creatinine; Disease Models, Animal; Heart Ventricles; Kidney; Lactates; Liver; Male; Myocardial Infarction; Proton Pump Inhibitors; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2013 |
Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency.
Topics: Amygdala; Analysis of Variance; Animals; Arginine; Biological Clocks; Cerebral Cortex; Depression; Disease Models, Animal; Electrodes, Implanted; Evoked Potentials; Fluoxetine; Hindlimb Suspension; Histidine; Humans; Immobility Response, Tonic; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Pathways; Neurons; Serotonin; Spectrum Analysis; Tryptophan Hydroxylase | 2013 |
The central role of arginine catabolism in T-cell dysfunction and increased susceptibility to infection after physical injury.
Topics: Animals; Arginase; Arginine; Disease Models, Animal; Listeriosis; Mice; Mice, Inbred C57BL; Myeloid Cells; T-Lymphocytes; Wounds and Injuries | 2014 |
Esophagoprotection mediated by exogenous and endogenous melatonin in an experimental model of reflux esophagitis.
Topics: Analysis of Variance; Animals; Arginine; Capsaicin; Digestive System Surgical Procedures; Disease Models, Animal; Esophagitis, Peptic; Esophagus; Male; Melatonin; Mucous Membrane; Nitric Oxide; Pineal Gland; Protective Agents; Rats; Rats, Wistar; Tryptophan | 2013 |
Effects of trimetazidine in acute pancreatitis induced by L-arginine.
Topics: Alanine Transaminase; Amylases; Animals; Arginine; Aspartate Aminotransferases; Disease Models, Animal; L-Lactate Dehydrogenase; Male; Pancreatitis; Rats; Rats, Wistar; Trimetazidine; Vasodilator Agents | 2013 |
Opposing roles of corticotropin-releasing factor and neuropeptide Y within the dorsolateral bed nucleus of the stria terminalis in the negative affective component of pain in rats.
Topics: Action Potentials; Affective Symptoms; Analysis of Variance; Aniline Compounds; Animals; Arginine; Corticotropin-Releasing Hormone; Cyclohexanes; Disease Models, Animal; Excitatory Amino Acid Antagonists; Formaldehyde; GABA Antagonists; Hormone Antagonists; Hormones; In Vitro Techniques; Kynurenic Acid; Male; Membrane Potentials; Microdialysis; Neurons; Neuropeptide Y; Pain; Pain Measurement; Peptide Fragments; Pyridazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Septal Nuclei; Xanthenes | 2013 |
Monitorization of asymmetric dimethylarginine (ADMA) levels in an experimental ischemia-reperfusion flap model: a preliminary report.
Topics: Abdominal Muscles; Animals; Arginine; Disease Models, Animal; Graft Rejection; Graft Survival; Male; Monitoring, Physiologic; Nitric Oxide; Nitric Oxide Synthase; Postoperative Period; Preoperative Period; Random Allocation; Rats; Rats, Wistar; Reference Values; Reperfusion Injury; Risk Factors; Skin Transplantation; Statistics, Nonparametric; Surgical Flaps | 2013 |
Involvement of opioidergic and nitrergic systems in memory acquisition and exploratory behaviors in cholestatic mice.
Topics: Analgesics, Opioid; Animals; Arginine; Avoidance Learning; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Ligation; Male; Memory Disorders; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide | 2013 |
Peripheral antinociception of a chalcone, flavokawin B and possible involvement of the nitric oxide/cyclic guanosine monophosphate/potassium channels pathway.
Topics: Analgesics; Animals; Arginine; Carrageenan; Chalcone; Cyclic GMP; Disease Models, Animal; Flavonoids; Hyperalgesia; Male; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Rats; Signal Transduction | 2013 |
Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo.
Topics: Adenosine; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cytosol; Disease Models, Animal; Drosophila melanogaster; Drosophila Proteins; Enzyme Inhibitors; Gene Deletion; Gene Knockdown Techniques; HEK293 Cells; Humans; Inclusion Bodies; Membrane Proteins; Methylation; Methyltransferases; Mutant Proteins; Mutation; Protein Binding; Protein Transport; Protein-Arginine N-Methyltransferases; Repressor Proteins; RNA-Binding Protein FUS; Subcellular Fractions | 2013 |
Evaluation of functional relationship between mouse hippocampal cholinergic and nitrergic systems in anxiogenic-like behavior.
Topics: Analysis of Variance; Animals; Anxiety; Arginine; Cholinergic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Male; Maze Learning; Mecamylamine; Mice; Microinjections; NG-Nitroarginine Methyl Ester; Nicotinic Antagonists; Nitric Oxide | 2013 |
High plasma concentrations of asymmetric dimethylarginine inhibit ischemic cardioprotection in hypercholesterolemic rats.
Topics: Animals; Arginine; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Hypercholesterolemia; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Rats; Rats, Wistar | 2013 |
Increased symmetrical dimethylarginine in ischemic acute kidney injury as a causative factor of renal L-arginine deficiency.
Topics: Acute Kidney Injury; Amidohydrolases; Animals; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Function Tests; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Tandem Mass Spectrometry | 2013 |
Global protein and histone arginine methylation are affected in a tissue-specific manner in a rat model of diet-induced hyperhomocysteinemia.
Topics: Animals; Arginine; Diet; Disease Models, Animal; Female; Histones; Hyperhomocysteinemia; Methylation; Proteins; Rats; Rats, Wistar | 2013 |
Effects of L-arginine on anatomical and electrophysiological deterioration of the eye in a rodent model of nonarteritic ischemic optic neuropathy.
Topics: Animals; Arginine; Cell Survival; Disease Models, Animal; Electroretinography; Evoked Potentials, Visual; Follow-Up Studies; Infusions, Intravenous; Male; Optic Neuropathy, Ischemic; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Tomography, Optical Coherence | 2013 |
Gender Based Differences in Stress-induced Gastric Ulcer Formation and its Regulation by Nitric Oxide (NO): An Experimental Study.
Topics: Androstenedione; Animals; Arginine; Aromatase Inhibitors; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogens; Female; Glutathione; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats, Wistar; Severity of Illness Index; Sex Factors; Signal Transduction; Stomach Ulcer; Stress, Psychological | 2015 |
Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.
Topics: Amidohydrolases; Animals; Arginine; Biomarkers; Cardiovascular Diseases; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Esomeprazole; Gastroesophageal Reflux; Humans; Lansoprazole; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Proton Pump Inhibitors; Risk Factors; Vasodilation | 2013 |
Light-emitting diode therapy induces analgesia in a mouse model of postoperative pain through activation of peripheral opioid receptors and the L-arginine/nitric oxide pathway.
Topics: Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Radiation; Injections, Spinal; Leukocytes; Male; Mice; Naloxone; Narcotic Antagonists; Nitric Oxide; Pain, Postoperative; Phototherapy; Receptors, Opioid | 2014 |
Arginase-II induces vascular smooth muscle cell senescence and apoptosis through p66Shc and p53 independently of its l-arginine ureahydrolase activity: implications for atherosclerotic plaque vulnerability.
Topics: Animals; Aorta; Apolipoproteins E; Apoptosis; Arginase; Arginine; Atherosclerosis; Cell Proliferation; Cells, Cultured; Cellular Senescence; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Genotype; Humans; Hydrolysis; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Muscle; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phenotype; Phosphorylation; Plaque, Atherosclerotic; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; RNA Interference; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Transfection; Tumor Suppressor Protein p53 | 2013 |
Integration-deficient lentiviral vectors expressing codon-optimized R338L human FIX restore normal hemostasis in Hemophilia B mice.
Topics: Animals; Arginine; Codon; Disease Models, Animal; Factor IX; Genetic Therapy; Genetic Vectors; Hemophilia B; Hep G2 Cells; Humans; Lentivirus; Leucine; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout | 2014 |
Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration.
Topics: Animals; Arginine; Bruch Membrane; Cell Adhesion; Complement C3; Complement System Proteins; Corneal Dystrophies, Hereditary; Disease Models, Animal; Extracellular Matrix Proteins; Gene Knock-In Techniques; Humans; Mice; Mice, Transgenic; Optic Disk Drusen; Point Mutation; Proteomics; Reproducibility of Results; Retinal Drusen; Tryptophan | 2014 |
Pathogen blocks host death receptor signalling by arginine GlcNAcylation of death domains.
Topics: Acylation; Animals; Apoptosis; Arginine; Death Domain Receptor Signaling Adaptor Proteins; Disease Models, Animal; Enteropathogenic Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; fas Receptor; Fas-Associated Death Domain Protein; HeLa Cells; Humans; Male; Mice; Mice, Inbred C57BL; Multiprotein Complexes; N-Acetylglucosaminyltransferases; NF-kappa B; Protein Biosynthesis; Protein Structure, Tertiary; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; TNF Receptor-Associated Death Domain Protein; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Virulence; Virulence Factors | 2013 |
Endothelial cell transfusion ameliorates endothelial dysfunction in 5/6 nephrectomized rats.
Topics: Acetylcholine; Amidohydrolases; Animals; Aorta; Arginine; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Male; Mesenteric Arteries; Myography; Nephrectomy; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Vasodilation; Vasodilator Agents | 2013 |
Modulation of NO and ROS production by AdiNOS transduced vascular cells through supplementation with L-Arg and BH4: implications for gene therapy of restenosis.
Topics: Adenoviridae; Animals; Aorta; Arginine; Biopterins; Carotid Arteries; Cell Proliferation; Cell Survival; Coronary Restenosis; Cross-Linking Reagents; Disease Models, Animal; Genetic Therapy; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2013 |
Alteplase treatment does not increase brain injury after mechanical middle cerebral artery occlusion in the rat.
Topics: Animals; Arginine; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Disease Models, Animal; Drug Carriers; Fibrinolytic Agents; Infarction, Middle Cerebral Artery; Male; Rats; Rats, Wistar; Survival Analysis; Tissue Plasminogen Activator | 2013 |
Akita spontaneously type 1 diabetic mice exhibit elevated vascular arginase and impaired vascular endothelial and nitrergic function.
Topics: Animals; Aorta; Arginase; Arginine; Blood Pressure; Boronic Acids; Diabetes Mellitus, Type 1; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Humans; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Penis | 2013 |
Delivery system for DNAzymes using arginine-modified hydroxyapatite nanoparticles for therapeutic application in a nasopharyngeal carcinoma model.
Topics: Absorption; Animals; Arginine; Carcinoma; Cell Line, Tumor; Cell Survival; Disease Models, Animal; DNA, Catalytic; Durapatite; Heterografts; Humans; Intracellular Space; Mice; Nanoparticles; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Transfection; Viral Matrix Proteins | 2013 |
Apelin-13 deteriorates hypertension in rats after damage of the vascular endothelium by ADMA.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Hypertension; Injections, Intravenous; Intercellular Signaling Peptides and Proteins; Male; Myosin Light Chains; Nitric Oxide; Phosphorylation; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction; Vasodilation; von Willebrand Factor | 2013 |
Homoarginine levels are regulated by L-arginine:glycine amidinotransferase and affect stroke outcome: results from human and murine studies.
Topics: Adult; Aged; Amidinotransferases; Animals; Arginine; Cohort Studies; Disease Models, Animal; Female; Genome-Wide Association Study; HEK293 Cells; Homoarginine; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Stroke; Treatment Outcome | 2013 |
Nitric oxide synthase inhibitors prevent the growth-inhibiting effects of quinpirole.
Topics: Animals; Animals, Newborn; Arginine; Chickens; Disease Models, Animal; Dopamine Agonists; Drug Combinations; Eye; Injections, Intraocular; Myopia; Nitric Oxide Synthase; Ornithine; Quinpirole; Refraction, Ocular; Sensory Deprivation; Ultrasonography | 2013 |
Paradoxical effects of heme arginate on survival of myocutaneous flaps.
Topics: Animals; Arginine; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Myocutaneous Flap; Necrosis; Rats; Rats, Inbred Lew; Reperfusion Injury; Skin | 2014 |
Glutamine supplementation, but not combined glutamine and arginine supplementation, improves gut barrier function during chemotherapy-induced intestinal mucositis in rats.
Topics: Animals; Arginine; Dietary Supplements; Disease Models, Animal; Gastrointestinal Tract; Glutamine; Immunohistochemistry; Intestines; Male; Methotrexate; Mucositis; NF-kappa B; Occludin; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2014 |
Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury.
Topics: Acute Lung Injury; Amidohydrolases; Animals; Arginine; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Genetic Therapy; Humans; Lipopolysaccharides; Lung; Male; Mice; Mice, Inbred C57BL; Microvessels; Oxidative Stress; Peroxynitrous Acid; Pulmonary Edema; Superoxides; Time Factors; Transfection; Up-Regulation | 2014 |
Beneficial effects of bumetanide in a CaV1.1-R528H mouse model of hypokalaemic periodic paralysis.
Topics: Acetazolamide; Animals; Arginine; Bumetanide; Calcium Channels, L-Type; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Evoked Potentials, Motor; Furosemide; Glucose; Histidine; Hypokalemic Periodic Paralysis; In Vitro Techniques; Isometric Contraction; Male; Mice; Mice, Transgenic; Muscle, Skeletal; Mutation; Sodium Potassium Chloride Symporter Inhibitors | 2013 |
Streptococcus pyogenes arginine and citrulline catabolism promotes infection and modulates innate immunity.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Gene Expression Regulation, Bacterial; Hydrolases; Immunity, Innate; Macrophages; Mice; Nitric Oxide Synthase Type II; Streptococcus pyogenes; Virulence | 2014 |
Diverse effects of parenteral arginine on systemic and local oxidant-antioxidant homeostasis and nitrosative stress in rats with subacute peritonitis.
Topics: Animals; Antioxidants; Arginine; Disease Models, Animal; Energy Intake; Homeostasis; Infusions, Parenteral; Kidney; Lipid Peroxidation; Male; Nitric Oxide; Oxidants; Oxidative Stress; Peritonitis; Rats; Rats, Wistar; Reactive Nitrogen Species; Reactive Oxygen Species; Severity of Illness Index; Tyrosine | 2014 |
Hypothermia induced by adenosine 5'-monophosphate attenuates injury in an L-arginine-induced acute pancreatitis rat model.
Topics: Acute Disease; Adenosine Monophosphate; Amylases; Animals; Arginine; Disease Models, Animal; Hypothermia, Induced; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Male; NF-kappa B; Pancreatitis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2014 |
A new mouse model of chronic pancreatitis in C57BL/6J strain that mimics the human pathology.
Topics: Animals; Arginine; Atrophy; Disease Models, Animal; Fibrosis; Humans; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis, Chronic | 2014 |
Intracellular Hmgb1 inhibits inflammatory nucleosome release and limits acute pancreatitis in mice.
Topics: Acute Disease; Animals; Arginine; Cell Death; Ceruletide; Disease Models, Animal; DNA Damage; High Mobility Group Proteins; Histones; Immunity, Innate; Mice; Mice, Inbred C57BL; Mice, Knockout; Nucleosomes; Oxidative Stress; Pancreas; Pancreatitis; Reactive Oxygen Species; Repressor Proteins; Signal Transduction; Time Factors | 2014 |
Metabolomic analysis of arginine metabolism in acute hepatic injury in rats.
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Biomarkers; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; Dose-Response Relationship, Drug; Isocyanates; Male; Metabolomics; Monocrotaline; Naphthalenes; Ornithine; Rats; Rats, Inbred F344; Tetramethylphenylenediamine | 2014 |
Long-term overexpression of human wild-type and T240R mutant Parkin in rat substantia nigra induces progressive dopaminergic neurodegeneration.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Arginine; Cell Death; Disease Models, Animal; Dopamine; Female; Green Fluorescent Proteins; HEK293 Cells; Humans; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Neurodegenerative Diseases; Rats; Rats, Wistar; Substantia Nigra; Threonine; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Ubiquitin-Protein Ligases | 2014 |
Insights into the mechanisms of macular degeneration associated with the R172W mutation in RDS.
Topics: Amino Acid Substitution; Animals; Arginine; Basic-Leucine Zipper Transcription Factors; Disease Models, Animal; Eye Proteins; Fundus Oculi; Humans; Macular Degeneration; Membrane Proteins; Mice; Mice, Transgenic; Peripherins; Retinal Cone Photoreceptor Cells; Tetraspanins; Tryptophan | 2014 |
Protein arginine hypomethylation in a mouse model of cystathionine β-synthase deficiency.
Topics: Animals; Arginine; Brain; Cystathionine beta-Synthase; Disease Models, Animal; DNA Methylation; Histones; Homocysteine; Homocystinuria; Liver; Methylation; Mice; S-Adenosylhomocysteine | 2014 |
Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Arginine; Cilostazol; Diet, High-Fat; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Humans; Intermittent Claudication; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Fatigue; Muscle, Skeletal; Nitric Oxide Synthase Type III; Obesity; Peripheral Vascular Diseases; Phosphodiesterase 3 Inhibitors; Physical Exertion; Tetrazoles; Vasodilator Agents | 2014 |
Panax quinquefolium involves nitric oxide pathway in olfactory bulbectomy rat model.
Topics: Anhedonia; Animals; Arginine; Brain; Corticosterone; Depressive Disorder; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Male; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Olfactory Bulb; Panax; Phytotherapy; Plant Preparations; Rats, Wistar; Signal Transduction | 2014 |
Histopathology and pathogenesis of caerulein-, duct ligation-, and arginine-induced acute pancreatitis in Sprague-Dawley rats and C57BL6 mice.
Topics: Animals; Arginine; Ceruletide; Disease Models, Animal; Ligation; Male; Mice; Mice, Inbred C57BL; Pancreatic Ducts; Pancreatitis; Rats; Rats, Sprague-Dawley | 2014 |
Low doses of arginine butyrate derivatives improve dystrophic phenotype and restore membrane integrity in DMD models.
Topics: Animals; Arginine; Butyrates; Cell Membrane Permeability; Cells, Cultured; Disease Models, Animal; Histone Deacetylase Inhibitors; Humans; Male; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscle Strength; Muscles; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Utrophin | 2014 |
The effect of L-arginine supplementation on serum resistin concentration in insulin resistance in animal models.
Topics: Adiposity; Animals; Arginine; Biomarkers; Blood Glucose; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Female; Insulin; Insulin Resistance; Male; Nitric Oxide; Obesity; Rats, Wistar; Resistin; Time Factors | 2014 |
Effects of l-arginine and creatine administration on spatial memory in rats subjected to a chronic variable stress model.
Topics: Animals; Arginine; Chronic Disease; Creatine; Disease Models, Animal; Male; Random Allocation; Rats; Rats, Wistar; Spatial Memory; Stress, Psychological; Treatment Outcome | 2014 |
Antidepressant-like effect of nitric oxide synthase inhibitors and sildenafil against lipopolysaccharide-induced depressive-like behavior in mice.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Brain; Brain-Derived Neurotrophic Factor; Cyclic GMP; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Imipramine; Interleukin-1beta; Lipopolysaccharides; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones | 2014 |
Mannose-binding lectin promotes local microvascular thrombosis after transient brain ischemia in mice.
Topics: Animals; Antithrombins; Arginine; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Fibrinogen; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mannose-Binding Lectin; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Pipecolic Acids; Reperfusion Injury; Sulfonamides; Thrombosis | 2014 |
Potential of birds to serve as pathology-free models of type 2 diabetes, part 2: do high levels of carbonyl-scavenging amino acids (e.g., taurine) and low concentrations of methylglyoxal limit the production of advanced glycation end-products?
Topics: Albumins; Animals; Arginine; Birds; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructosamine; Glucose; Glycation End Products, Advanced; Lysine; Maillard Reaction; Pyruvaldehyde; Taurine | 2014 |
Effect of lowering asymmetric dimethylarginine (ADMA) on vascular pathology in atherosclerotic ApoE-deficient mice with reduced renal mass.
Topics: Amidohydrolases; Animals; Aorta; Apolipoproteins E; Arginine; Atherosclerosis; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Nitric Oxide Synthase; Plaque, Atherosclerotic; Renal Insufficiency, Chronic; Transaminases | 2014 |
Hippocampal nNOS inhibition induces an antidepressant-like effect: involvement of 5HT1A receptors.
Topics: Animals; Antidepressive Agents; Arginine; Disease Models, Animal; Enzyme Inhibitors; Exploratory Behavior; Fluoxetine; Hippocampus; Male; Nitric Oxide Synthase Type I; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Stress, Psychological; Swimming | 2014 |
Reciprocal changes in phosphorylation and methylation of mammalian brain sodium channels in response to seizures.
Topics: Action Potentials; Animals; Arginine; Brain; Cell Line; Disease Models, Animal; Epilepsy; Excitatory Amino Acid Agonists; Kainic Acid; Kidney; Male; Mass Spectrometry; Methylation; NAV1.2 Voltage-Gated Sodium Channel; Phosphorylation; Proteomics; Rats | 2014 |
Angiotensin II type 1 receptor blocker losartan prevents and rescues cerebrovascular, neuropathological and cognitive deficits in an Alzheimer's disease model.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Angiotensin II Type 1 Receptor Blockers; Animals; Arginine; Blood Pressure; Brain; Cerebrovascular Circulation; Cognition Disorders; Disease Models, Animal; Endothelin-1; Enzyme Inhibitors; Female; Gene Expression Regulation; Humans; Losartan; Male; Mice; Mice, Transgenic; Mutation | 2014 |
Characterization of the mitofusin 2 R94W mutation in a knock-in mouse model.
Topics: Animals; Animals, Newborn; Arginine; Cells, Cultured; Charcot-Marie-Tooth Disease; Disease Models, Animal; Escape Reaction; Exploratory Behavior; Fibroblasts; GTP Phosphohydrolases; Humans; In Vitro Techniques; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Proteins; Motor Activity; Muscle Strength; Oxygen Consumption; Point Mutation; Psychomotor Performance; Tryptophan | 2014 |
Effects of oleuropein in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium, Vascular; Hypertension, Renal; Iridoid Glucosides; Iridoids; Male; Molecular Structure; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2014 |
The effects of coenzyme Q10 on seizures in mice: the involvement of nitric oxide.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Electroshock; Epilepsy, Tonic-Clonic; Guanidines; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Seizures; Ubiquinone | 2014 |
Role of alanine:glyoxylate aminotransferase 2 in metabolism of asymmetric dimethylarginine in the settings of asymmetric dimethylarginine overload and bilateral nephrectomy.
Topics: Acute Kidney Injury; Alanine; Animals; Arginine; Biomarkers; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Infusions, Intravenous; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Nephrectomy; Real-Time Polymerase Chain Reaction; RNA; Transaminases | 2014 |
p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-uncoupling in obesity.
Topics: Animals; Arginase; Arginine; Diet, High-Fat; Disease Models, Animal; Endothelium, Vascular; Humans; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction | 2014 |
Maladjusted host immune responses induce experimental cerebral malaria-like pathology in a murine Borrelia and Plasmodium co-infection model.
Topics: Animals; Arginine; Borrelia; Borrelia Infections; Coinfection; Dendritic Cells; Disease Models, Animal; Endothelium; Female; Histocompatibility Antigens Class II; Host-Pathogen Interactions; Interleukin-10; Macrophage Activation; Macrophages; Malaria, Cerebral; Mice; Plasmodium; Signal Transduction; T-Lymphocyte Subsets | 2014 |
Investigating the cardio-protective abilities of supplemental L-arginine on parameters of endothelial function in a hypercholesterolemic animal model.
Topics: Amidohydrolases; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Cardiotonic Agents; Cardiovascular Diseases; Dietary Supplements; Disease Models, Animal; Enalapril; Endothelium, Vascular; Heart; Hypercholesterolemia; Male; Malondialdehyde; Nitric Oxide; Nitroglycerin; Oxidative Stress; Rabbits | 2014 |
Neuropeptide Y attenuates anxiety- and depression-like effects of cholecystokinin-4 in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Arginine; Brain; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Immunohistochemistry; Male; Mice; Motor Activity; Neuropeptide Y; Neuropsychological Tests; Psychotropic Drugs; Receptors, Neuropeptide Y; Social Behavior; Swimming; Tetragastrin | 2014 |
Effects of inhaled L-arginine administration in a murine model of acute asthma.
Topics: Acute Disease; Animals; Arginine; Asthma; Bronchoconstrictor Agents; Bronchodilator Agents; Budesonide; Disease Models, Animal; Male; Methacholine Chloride; Mice; Mice, Inbred BALB C; Nitric Oxide; Time Factors | 2014 |
Arginine butyrate per os protects mdx mice against cardiomyopathy, kyphosis and changes in axonal excitability.
Topics: Action Potentials; Animals; Antineoplastic Agents; Arginine; Axons; Butyrates; Cardiomyopathies; Disease Models, Animal; Dystrophin; Electrocardiography; Kyphosis; Magnetic Resonance Imaging; Mice; Mice, Inbred C57BL; Muscle Strength; Muscle, Skeletal; Muscular Dystrophies; Severity of Illness Index; Time Factors; Tomography, X-Ray Computed; Ureohydrolases | 2014 |
Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas.
Topics: Animals; Arginase; Arginine; Cell Proliferation; Disease Models, Animal; Granuloma; Humans; Hypoxia; Lung; Macrophages; Mice; Mice, Knockout; Mycobacterium tuberculosis; Nitric Oxide; Nitric Oxide Synthase Type II; T-Lymphocytes; Tuberculosis, Pulmonary | 2014 |
Changes in ADMA/DDAH pathway after hepatic ischemia/reperfusion injury in rats: the role of bile.
Topics: Amidohydrolases; Animals; Arginine; Bile; Cationic Amino Acid Transporter 2; Disease Models, Animal; Liver; Male; Organ Specificity; Oxidative Stress; Protein-Arginine N-Methyltransferases; Rats; Rats, Wistar; Reperfusion Injury | 2014 |
Protective effect of ethyl pyruvate on ischemia-reperfusion injury in rat ovary: biochemical and histopathological evaluation.
Topics: Animals; Antioxidants; Arginine; Disease Models, Animal; Female; Malondialdehyde; Ovary; Pyruvates; Rats; Rats, Wistar; Reperfusion Injury; Torsion Abnormality | 2014 |
Serelaxin reduces oxidative stress and asymmetric dimethylarginine in angiotensin II-induced hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Arginine; Arterial Pressure; Dinoprost; Disease Models, Animal; Down-Regulation; Humans; Hypertension; Injections, Subcutaneous; Kidney; Liver; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Proteinuria; Rats, Sprague-Dawley; Recombinant Proteins; Relaxin; Thiobarbituric Acid Reactive Substances | 2014 |
Cardioprotective effects of oxymatrine on isoproterenol-induced heart failure via regulation of DDAH/ADMA metabolism pathway in rats.
Topics: Alkaloids; Amidohydrolases; Animals; Arginine; Cardiotonic Agents; Disease Models, Animal; Female; Heart Failure; Hemodynamics; Isoproterenol; Male; Metabolic Networks and Pathways; Myocardium; Natriuretic Peptide, Brain; Organ Size; Protein-Arginine N-Methyltransferases; Quinolizines; Rats; Rats, Sprague-Dawley; Troponin I | 2014 |
A novel acute necrotizing pancreatitis model induced by L-arginine in rats.
Topics: Amylases; Animals; Apoptosis; Arginine; Biomarkers; Disease Models, Animal; Edema; Granulocytes; Male; Monocytes; Necrosis; Neutrophil Infiltration; Pancreas; Pancreatitis, Acute Necrotizing; Rats, Sprague-Dawley; Time Factors; Up-Regulation | 2015 |
Nanovector-based prolyl hydroxylase domain 2 silencing system enhances the efficiency of stem cell transplantation for infarcted myocardium repair.
Topics: Animals; Arginine; Disease Models, Animal; Drug Delivery Systems; Gene Silencing; Heart; Hypoxia-Inducible Factor-Proline Dioxygenases; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardium; Nanoparticles; Polyamines; RNA, Small Interfering | 2014 |
Immunomodulatory and antioxidant function of albumin stabilises the endothelium and improves survival in a rodent model of chronic liver failure.
Topics: Albumins; Animals; Arginine; Disease Models, Animal; End Stage Liver Disease; Endothelium, Vascular; Hemodynamics; Humans; Inflammation; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; von Willebrand Factor | 2015 |
Overexpression of NMDAR2B in an inflammatory model of Alzheimer's disease: modulation by NOS inhibitors.
Topics: Alzheimer Disease; Amidines; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Benzylamines; Brain; Diflunisal; Disease Models, Animal; Enzyme Inhibitors; Exploratory Behavior; Gene Expression Regulation; Inflammation; Lipopolysaccharides; Male; Maze Learning; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate | 2014 |
Effects of morphine on stress induced anxiety in rats: role of nitric oxide and Hsp70.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anxiety; Arginine; Brain; Chronic Disease; Disease Models, Animal; Drug Synergism; HSP70 Heat-Shock Proteins; Male; Morphine; Nitric Oxide; Rats, Wistar; Restraint, Physical; Stress, Psychological | 2015 |
Involvement of the nitrergic system in the proconvulsant effect of social isolation stress in male mice.
Topics: Animals; Arginine; Convulsants; Disease Models, Animal; Enzyme Inhibitors; Hippocampus; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Seizures; Social Isolation; Stress, Psychological | 2014 |
Changes in skeletal collagen cross-links and matrix hydration in high- and low-turnover chronic kidney disease.
Topics: Amino Acids; Animals; Arginine; Body Water; Bone and Bones; Bone Matrix; Collagen; Diaphyses; Disease Models, Animal; Femur; Lysine; Male; Rats; Renal Insufficiency, Chronic; Stress, Mechanical | 2015 |
Effect of 18β-glycyrrhetinic acid on cerebral vasospasm caused by asymmetric dimethylarginine after experimental subarachnoid hemorrhage in rats.
Topics: Animals; Arginine; Basilar Artery; Blotting, Western; Connexin 43; Connexins; Disease Models, Animal; Glycyrrhetinic Acid; Neuroprotective Agents; Random Allocation; Rats, Sprague-Dawley; Severity of Illness Index; Subarachnoid Hemorrhage; Time Factors; Vasospasm, Intracranial | 2015 |
Dimethyl fumarate ameliorates acute pancreatitis in rodent.
Topics: Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Arginine; Biomarkers; Cytokines; Dimethyl Fumarate; Disease Models, Animal; Inflammation Mediators; Lipid Peroxidation; Male; Malondialdehyde; Pancreas; Pancreatitis; Rats, Sprague-Dawley; Severity of Illness Index; Spleen | 2015 |
Nitric oxide involvement in the antidepressant-like effect of ketamine in the Flinders sensitive line rat model of depression.
Topics: Anesthetics, Dissociative; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Cyclic GMP; Depression; Disease Models, Animal; Frontal Lobe; Hippocampus; Ketamine; Male; Motor Activity; Nitric Oxide; Random Allocation; Rats; Receptors, N-Methyl-D-Aspartate | 2015 |
Heme Oxygenase Improves Renal Function by Potentiating Podocyte-Associated Proteins in Nω-Nitro-l-Arginine-Methyl Ester (l-NAME)-Induced Hypertension.
Topics: Animals; Arginine; Biomarkers; Cytoprotection; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibrosis; Heme; Heme Oxygenase (Decyclizing); Hypertension; Inflammation Mediators; Kidney; Male; Mesoporphyrins; NG-Nitroarginine Methyl Ester; Oxidative Stress; Podocytes; Rats, Sprague-Dawley; Signal Transduction | 2015 |
Asymmetric dimethylarginine exacerbates Aβ-induced toxicity and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Animals, Genetically Modified; Arginine; Caenorhabditis elegans; Disease Models, Animal; Gene Knockdown Techniques; Humans; MAP Kinase Signaling System; Oxidative Stress; Protein-Arginine N-Methyltransferases; Repressor Proteins | 2015 |
Mechanism and consequences of the shift in cardiac arginine metabolism following ischaemia and reperfusion in rats.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginase; Arginine; Captopril; Disease Models, Animal; Isolated Heart Preparation; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Polyamines; Rats; Recovery of Function; Renin-Angiotensin System; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Ventricular Function, Left | 2015 |
Mechanisms of α-mangostin-induced antinociception in a rodent model.
Topics: Analgesics; Animals; Arginine; Capsaicin; Disease Models, Animal; Glutamic Acid; Male; Mice; Mice, Inbred ICR; NG-Nitroarginine Methyl Ester; Rats; Xanthones | 2015 |
Regulation of the arginine deiminase system by ArgR2 interferes with arginine metabolism and fitness of Streptococcus pneumoniae.
Topics: Animals; Arginine; Bacterial Proteins; Disease Models, Animal; DNA, Bacterial; Gene Deletion; Gene Expression Regulation, Bacterial; Hydrolases; Mice; Multigene Family; Pneumococcal Infections; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Streptococcus pneumoniae; Virulence | 2014 |
Arginase inhibition prevents bleomycin-induced pulmonary hypertension, vascular remodeling, and collagen deposition in neonatal rat lungs.
Topics: Aminocaproates; Animals; Antibiotics, Antineoplastic; Arginase; Arginine; Bleomycin; Boron Compounds; Bronchopulmonary Dysplasia; Collagen; Disease Models, Animal; Hypertension, Pulmonary; Lung; Lung Injury; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Remodeling | 2015 |
Poly-arginine and arginine-rich peptides are neuroprotective in stroke models.
Topics: Animals; Arginine; Calcium; Cells, Cultured; Disease Models, Animal; Endocytosis; Glutamic Acid; Heparan Sulfate Proteoglycans; Male; Neurons; Neuroprotective Agents; Peptides; Rats, Sprague-Dawley; Stroke | 2015 |
New insights into the methodology of L-arginine-induced acute pancreatitis.
Topics: Amylases; Animals; Arginine; Disease Models, Animal; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase | 2015 |
Involvement of nitric oxide in serotonin-induced scratching in mice.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Injections, Intradermal; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pruritus; Serotonin; Serotonin Receptor Agonists | 2015 |
Investigation of the effects of enteral hormones on the pyloric muscle in newborn rats.
Topics: Animals; Animals, Newborn; Arginine; Disease Models, Animal; Enzyme Inhibitors; Female; Male; NG-Nitroarginine Methyl Ester; Pyloric Stenosis, Hypertrophic; Pylorus; Rats; Rats, Wistar | 2015 |
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair.
Topics: Alcohol Oxidoreductases; Animals; Arginine; Brain; Brain Diseases, Metabolic, Inborn; Cells, Cultured; Disease Models, Animal; Female; Glutarates; Ketone Oxidoreductases; Lysine; Male; Mice; Mice, Knockout; Testis | 2015 |
Plasma asymmetric and symmetric dimethylarginine in a rat model of endothelial dysfunction induced by acute hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Cathepsin D; Disease Models, Animal; Endothelium, Vascular; Gene Expression Regulation; Hyperhomocysteinemia; Liver; Male; Methionine; Rats; Rats, Wistar; Ubiquitin | 2015 |
l-Arginine Attenuates Cardiac Dysfunction, But Further Down-Regulates α-Myosin Heavy Chain Expression in Isoproterenol-Induced Cardiomyopathy.
Topics: Amidohydrolases; Animals; Arginine; Cardiomyopathies; Cardiotonic Agents; Disease Models, Animal; Down-Regulation; Fibrosis; Heart Rate; Isoproterenol; Male; Membrane Glycoproteins; Myosin Heavy Chains; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Protein-Arginine N-Methyltransferases; Rats, Wistar; RNA, Messenger; Time Factors; Ventricular Function, Left; Ventricular Myosins; Ventricular Pressure | 2015 |
[Expression of long chain fatty acid oxidase in maternal and fetal tissues in preeclampsia-like mouse model in mid-gestation].
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Arginine; Cardiomyopathies; Disease Models, Animal; Fatty Acids; Female; Fetal Development; Fetus; Humans; Lipid Metabolism, Inborn Errors; Liver; Mice; Mice, Inbred C57BL; Mitochondrial Myopathies; Mitochondrial Trifunctional Protein; Nervous System Diseases; Oxidation-Reduction; Oxidoreductases; Placenta; Pre-Eclampsia; Pregnancy; Rhabdomyolysis | 2015 |
Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease.
Topics: Age Factors; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigens, CD; Arginine; Brain; Disease Models, Animal; Disease Progression; Eflornithine; Humans; Immunologic Factors; Maze Learning; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Microglia; Mutation; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors | 2015 |
Depletion of neutrophils protects against L-arginine-induced acute pancreatitis in mice.
Topics: Acute Disease; Amylases; Animals; Apoptosis; Arginine; Cytokines; Disease Models, Animal; Lung; Male; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Pancreas; Pancreatitis; Peroxidase; Reactive Oxygen Species | 2015 |
H2S mitigates severe acute pancreatitis through the PI3K/AKT-NF-κB pathway in vivo.
Topics: Alkynes; Animals; Anti-Inflammatory Agents; Arginine; Cystathionine gamma-Lyase; Cytoprotection; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Glycine; Inflammation Mediators; Male; NF-kappa B; Pancreas; Pancreatitis, Acute Necrotizing; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Severity of Illness Index; Signal Transduction; Sulfides | 2015 |
Tumor-specific delivery of BSH-3R for boron neutron capture therapy and positron emission tomography imaging in a mouse brain tumor model.
Topics: Animals; Arginine; Boron; Boron Neutron Capture Therapy; Boronic Acids; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Copper; Disease Models, Animal; Drug Delivery Systems; Female; Glioma; Heterocyclic Compounds, 1-Ring; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Oligopeptides; Peptides; Positron-Emission Tomography; Tomography, X-Ray Computed | 2015 |
Augmented endothelial l-arginine transport ameliorates pressure-overload-induced cardiac hypertrophy.
Topics: Animals; Arginine; Cardiomegaly; Disease Models, Animal; Endothelium, Vascular; Hypertrophy, Left Ventricular; Mice, Transgenic; Myocardium; Myocytes, Cardiac; Pressure; Ventricular Dysfunction, Left | 2015 |
Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice.
Topics: Alternative Splicing; Animals; Animals, Newborn; Arginine; Diaphragm; Disease Models, Animal; Dystrophin; Exons; Genetic Therapy; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Morpholinos; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Myostatin; Necrosis; Oligonucleotides, Antisense; Open Reading Frames; Peptides; Reading Frames | 2015 |
Neuropeptide FF receptors as novel targets for limbic seizure attenuation.
Topics: Adamantane; Animals; Anticonvulsants; Arginine; CHO Cells; Cricetulus; Dipeptides; Disease Models, Animal; HEK293 Cells; Humans; Limbic System; Male; Pilocarpine; Rats, Wistar; Receptors, Neuropeptide; Receptors, Neuropeptide Y; Seizures | 2015 |
Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice.
Topics: Amylases; Animals; Arginine; Ceruletide; Disease Models, Animal; Epoxide Hydrolases; Gene Expression Regulation; Interleukin-1beta; Interleukin-6; Lipase; MAP Kinase Signaling System; Mice; Pancreatitis; Phenylurea Compounds; Piperidines; Tumor Necrosis Factor-alpha | 2015 |
Effects of L-arginine and L-NAME on ischemia-reperfusion in rat liver.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Disease Models, Animal; Enzyme Inhibitors; Liver; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats, Wistar; Reference Values; Reperfusion Injury; Reproducibility of Results; Time Factors; Treatment Outcome | 2015 |
[Dynamics of reparative processes in wall of a small bowel loop after elimination of its acute mechanical ileus, depending on duration of incarceration].
Topics: Animals; Arginine; Disease Models, Animal; Electrochemotherapy; Ileus; Intestine, Small; Rats; Recovery of Function; Sorbitol | 2015 |
Role of bone marrow mesenchymal stem cells in L-arg-induced acute pancreatitis: effects and possible mechanisms.
Topics: Animals; Arginine; Blotting, Western; Bone Marrow Cells; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunohistochemistry; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Pancreatitis; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction | 2015 |
Antidepressant-like effect of quercetin in bulbectomized mice and involvement of the antioxidant defenses, and the glutamatergic and oxidonitrergic pathways.
Topics: Animals; Antidepressive Agents; Antioxidants; Arginine; Behavior, Animal; Disease Models, Animal; Drug Synergism; Fluoxetine; Hippocampus; Indazoles; Male; Methylene Blue; Mice; N-Methylaspartate; Olfactory Bulb; Oxidative Stress; Quercetin; Signal Transduction; Sildenafil Citrate | 2015 |
Evaluation of ADMA-DDAH-NOS axis in specific brain areas following nitroglycerin administration: study in an animal model of migraine.
Topics: Amidohydrolases; Animals; Arginine; Brain; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Migraine Disorders; Nitric Oxide Synthase Type I; Nitroglycerin; Rats; Rats, Sprague-Dawley | 2015 |
Neutrophil Extracellular Traps Induce Trypsin Activation, Inflammation, and Tissue Damage in Mice With Severe Acute Pancreatitis.
Topics: Acute Disease; Animals; Arginine; Case-Control Studies; Deoxyribonuclease I; Disease Models, Animal; DNA; Enzyme Activation; Extracellular Traps; Humans; Inflammation Mediators; Lung; Male; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; Pancreas; Pancreatitis; Severity of Illness Index; Taurocholic Acid; Trypsin | 2015 |
Temporal profile of the vascular anatomy evaluated by 9.4-tesla magnetic resonance angiography and histological analysis in mice with the R4859K mutation of RNF213, the susceptibility gene for moyamoya disease.
Topics: Adenosine Triphosphatases; Analysis of Variance; Animals; Arginine; Blood Vessels; Brain; Disease Models, Animal; Humans; Hyperplasia; Image Processing, Computer-Assisted; Lysine; Magnetic Resonance Angiography; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Moyamoya Disease; Mutation; Time Factors; Ubiquitin-Protein Ligases | 2015 |
The Fur homologue BosR requires Arg39 to activate rpoS transcription in Borrelia burgdorferi and thereby direct spirochaete infection in mice.
Topics: Amino Acid Substitution; Animals; Arginine; Bacterial Proteins; Borrelia burgdorferi; Disease Models, Animal; Gene Expression Regulation, Bacterial; Lyme Disease; Mice; Mutant Proteins; Mutation, Missense; Sigma Factor; Trans-Activators; Transcription, Genetic; Virulence; Virulence Factors | 2015 |
Human recombinant arginase enzyme reduces plasma arginine in mouse models of arginase deficiency.
Topics: Animals; Arginase; Arginine; Brain; Child; Child, Preschool; Cohort Studies; Disease Models, Animal; Female; Humans; Hyperammonemia; Hyperargininemia; Longitudinal Studies; Macaca fascicularis; Male; Mice; Mice, Inbred C57BL; Recombinant Proteins; Seizures | 2015 |
Effects of 18-month treatment with bazedoxifene on enzymatic immature and mature cross-links and non-enzymatic advanced glycation end products, mineralization, and trabecular microarchitecture of vertebra in ovariectomized monkeys.
Topics: Animals; Arginine; Bone Density; Bone Density Conservation Agents; Collagen; Cross-Linking Reagents; Disease Models, Animal; Female; Glycation End Products, Advanced; Humans; Indoles; Lumbar Vertebrae; Lysine; Macaca fascicularis; Osteoporosis, Postmenopausal; Ovariectomy; Selective Estrogen Receptor Modulators; X-Ray Microtomography | 2015 |
Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis.
Topics: Amidohydrolases; Animals; Arginine; Case-Control Studies; Disease Models, Animal; Endothelium, Vascular; Gambia; Homeostasis; Humans; Liver; Malaria; Mice; Nitric Oxide | 2015 |
A new experimental rat model of pancreatitis using Ecballium elaterium.
Topics: Acute Disease; Amylases; Animals; Antioxidants; Arginine; Cucurbitaceae; Disease Models, Animal; Edema; Hemorrhage; Interleukin-1beta; Interleukin-6; Lung; Male; Malondialdehyde; Mice; Necrosis; Pancreas; Pancreatitis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2015 |
Uncoupling of Endothelial Nitric Oxide Synthase in Perivascular Adipose Tissue of Diet-Induced Obese Mice.
Topics: Adipocytes; Adipokines; Adipose Tissue; Adiposity; Animals; Aorta, Thoracic; Arginase; Arginine; Cytokines; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Inflammation Mediators; Male; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Paracrine Communication; Phosphorylation; Signal Transduction; Superoxides; Vasodilation; Vasodilator Agents | 2016 |
The fusion of autophagosome with lysosome is impaired in L-arginine-induced acute pancreatitis.
Topics: Acute Disease; Adaptor Proteins, Signal Transducing; Animals; Arginine; Autophagy; Biomarkers; Blotting, Western; Disease Models, Animal; Heat-Shock Proteins; Lysosomal-Associated Membrane Protein 2; Lysosomes; Male; Membrane Fusion; Mice; Microscopy, Electron, Scanning; Pancreas; Pancreatitis; Sequestosome-1 Protein | 2015 |
Possible involvement of nitrergic and opioidergic systems in the modulatory effect of acute chloroquine treatment on pentylenetetrazol induced convulsions in mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anticonvulsants; Arginine; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Hippocampus; Indazoles; Male; Mice; Naltrexone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors | 2016 |
[Variation of long-chain 3-hydroxyacyl-CoA dehydrogenase DNA methylation in placenta of different preeclampsia-like mouse models].
Topics: 3-Hydroxyacyl CoA Dehydrogenases; 3-Hydroxyacyl-CoA Dehydrogenase; Animals; Arginine; Cardiomyopathies; Disease Models, Animal; DNA Methylation; Fatty Acids; Female; Humans; Lipid Metabolism; Lipid Metabolism, Inborn Errors; Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase; Mice; Mitochondrial Myopathies; Mitochondrial Trifunctional Protein; Nervous System Diseases; Oxidation-Reduction; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Rhabdomyolysis | 2015 |
Recombinant Reg3α protein protects against experimental acute pancreatitis in mice.
Topics: Acinar Cells; Animals; Antigens, Neoplasm; Apoptosis; Arginine; Biomarkers, Tumor; Cell Line; Cell Proliferation; Disease Models, Animal; Female; Gene Expression Regulation; Humans; Lectins, C-Type; Mice; Pancreatitis; Pancreatitis-Associated Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Signal Transduction | 2016 |
Ilex paraguariensis hydroalcoholic extract exerts antidepressant-like and neuroprotective effects: involvement of the NMDA receptor and the L-arginine-NO pathway.
Topics: Animals; Antidepressive Agents; Arginine; Cell Survival; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hindlimb Suspension; Hippocampus; Ilex paraguariensis; Male; Mice; Neuroprotective Agents; Nitric Oxide; Plant Extracts; Receptors, N-Methyl-D-Aspartate; Signal Transduction; South America | 2016 |
TLR4-mediated NF-κB signaling pathway mediates HMGB1-induced pancreatic injury in mice with severe acute pancreatitis.
Topics: Acute Disease; Animals; Arginine; Disease Models, Animal; HMGB1 Protein; Humans; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pancreas; Pancreatitis; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 4 | 2016 |
Antidepressant Effect of Cnestis ferruginea Vahl ex DC (Connaraceae): Involvement of Cholinergic, Monoaminergic and L-arginine-nitric Oxide Pathways.
Topics: Animals; Antidepressive Agents; Arginine; Behavior, Animal; Cholinergic Antagonists; Connaraceae; Depression; Disease Models, Animal; Male; Medicine, African Traditional; Mice; Motor Activity; Nigeria; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Plant Extracts; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Signal Transduction; Swimming | 2016 |
Neuropeptide Y Impairs Retrieval of Extinguished Fear and Modulates Excitability of Neurons in the Infralimbic Prefrontal Cortex.
Topics: Animals; Arginine; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Corticosterone; Disease Models, Animal; Dose-Response Relationship, Drug; Extinction, Psychological; Fear; Glutamate Decarboxylase; Learning Disabilities; Male; Mental Recall; Neurons; Neuropeptide Y; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Synaptic Potentials | 2016 |
Mixture of Arginine, Glutamine, and β-hydroxy-β-methyl Butyrate Enhances the Healing of Ischemic Wounds in Rats.
Topics: Animals; Arginine; Collagen; Disease Models, Animal; Glutamine; Hydroxyproline; Ischemia; Rats; Rats, Wistar; Valerates; Wound Healing | 2017 |
Ameliorative Effects of Curcumin on Fibrinogen-Like Protein-2 Gene Expression, Some Oxido-Inflammatory and Apoptotic Markers in a Rat Model of l-Arginine-Induced Acute Pancreatitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Caspase 3; Curcumin; Disease Models, Animal; Fibrinogen; Gene Expression Regulation; Inflammation; Injections, Intraperitoneal; Male; Oxidative Stress; Pancreatitis, Acute Necrotizing; Peroxidase; Protein Carbonylation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 2016 |
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD.
Topics: Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Nucleus; Dipeptides; Disease Models, Animal; Drosophila melanogaster; Eye; Frontotemporal Dementia; Genes, Insect; Genetic Testing; HeLa Cells; Humans; Methylation; Repetitive Sequences, Amino Acid; RNA Interference | 2016 |
Possible involvement of L-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like effect of Wuling mycelia powder in rat.
Topics: Animals; Antidepressive Agents; Arginine; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Feeding Behavior; Food Preferences; Hippocampus; Indazoles; Male; Methylene Blue; Mycelium; Nitric Oxide; Powders; Rats, Sprague-Dawley; Signal Transduction; Sildenafil Citrate; Stress, Psychological; Sucrose | 2016 |
Nitric oxide pathway activity modulation alters the protective effects of (-)Epigallocatechin-3-gallate on reserpine-induced impairment in rats.
Topics: Animals; Arginine; Catechin; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Glutathione; Hippocampus; Lipid Peroxidation; Male; Memory Disorders; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reserpine; Signal Transduction; Smell; Superoxide Dismutase | 2016 |
Asymmetric Dimethylarginine Stimulates Akt1 Phosphorylation via Heat Shock Protein 70-Facilitated Carboxyl-Terminal Modulator Protein Degradation in Pulmonary Arterial Endothelial Cells.
Topics: Animals; Arginine; Carrier Proteins; Disease Models, Animal; Endothelial Cells; Genes, Dominant; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Lung; Mitochondria; Nitric Oxide Synthase Type III; Phosphorylation; Proteasome Endopeptidase Complex; Protein Binding; Proteolysis; Proto-Oncogene Proteins c-akt; Pulmonary Artery; Regional Blood Flow; Sheep; Ubiquitination | 2016 |
Histological and immunohistochemical effects of L-arginine and silymarin on TNBS-induced inflammatory bowel disease in rats.
Topics: Animals; Antioxidants; Arginine; Disease Models, Animal; Immunohistochemistry; Inflammatory Bowel Diseases; Male; Random Allocation; Rats; Silymarin; Trinitrobenzenesulfonic Acid | 2016 |
Anti-B7-H3 monoclonal antibody ameliorates the damage of acute experimental pancreatitis by attenuating the inflammatory response.
Topics: Acinar Cells; Acute Disease; Animals; Antibodies, Monoclonal; Arginine; B7 Antigens; Cells, Cultured; Cytokines; Disease Models, Animal; Humans; Immunotherapy; Inflammation; Inflammation Mediators; Macrophages; Male; Mice; Mice, Inbred Strains; NF-kappa B; Pancreatitis; Signal Transduction | 2016 |
The "Rise-Peak-Fall" Pattern of Time Dependency of the Cardiovascular Pleiotropic Effects of Treatment With Low-dose Atorvastatin, Losartan, and a Combination Thereof in Rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Arginine; Atorvastatin; Cardiovascular System; Carrier Proteins; CD40 Antigens; Coronary Circulation; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isolated Heart Preparation; Losartan; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Rats, Wistar; Time Factors; Vasodilation | 2016 |
Effect of tiron on remote organ injury in rats with severe acute pancreatitis induced by L-arginine.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acute Disease; Animals; Antioxidants; Arginine; Biomarkers; Cytoprotection; Disease Models, Animal; Glutathione; Kidney; Lipid Peroxidation; Liver; Lung; Male; Malondialdehyde; Multiple Organ Failure; NF-kappa B; Nitric Oxide; Oxidative Stress; Pancreas; Pancreatitis; Rats, Wistar; Severity of Illness Index; Superoxide Dismutase; Transforming Growth Factor beta1 | 2016 |
Oncological miR-182-3p, a Novel Smooth Muscle Cell Phenotype Modulator, Evidences From Model Rats and Patients.
Topics: Animals; Arginine; Carotid Artery Diseases; Carotid Artery Injuries; Cell Differentiation; Cell Movement; Cell Proliferation; Cells, Cultured; Coronary Artery Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Profiling; Gene Expression Regulation; Humans; Male; MicroRNAs; Muscle, Smooth, Vascular; Myelin and Lymphocyte-Associated Proteolipid Proteins; Myocytes, Smooth Muscle; Neointima; Oligonucleotide Array Sequence Analysis; Phenotype; Rats, Sprague-Dawley; RNA Interference; Signal Transduction; Transfection; Vascular Remodeling | 2016 |
Evidence for the involvement of neuropeptide Y in the antidepressant effect of imipramine in type 2 diabetes.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Blood Glucose; Central Amygdaloid Nucleus; Depression; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Imipramine; Male; Mice; Motor Activity; Neuropeptide Y; Nucleus Accumbens; Receptors, Neuropeptide Y; Septal Nuclei; Streptozocin | 2016 |
miR-29a up-regulation in AR42J cells contributes to apoptosis via targeting TNFRSF1A gene.
Topics: Animals; Apoptosis; Arginine; Blotting, Western; Computational Biology; Disease Models, Animal; Flow Cytometry; Gene Expression Profiling; HEK293 Cells; Humans; In Situ Nick-End Labeling; Male; MicroRNAs; Oligonucleotide Array Sequence Analysis; Pancreas, Exocrine; Pancreatitis; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Time Factors; Transfection; Up-Regulation | 2016 |
Improvement of in vivo antimicrobial activity of HBcARD peptides by D-arginine replacement.
Topics: Animals; Anti-Infective Agents; Arginine; Disease Models, Animal; Hepatitis B Core Antigens; Mice, Inbred ICR; Microbial Viability; Peptides; Staphylococcal Infections; Treatment Outcome | 2016 |
L-Arginine supplementation inhibits the growth of breast cancer by enhancing innate and adaptive immune responses mediated by suppression of MDSCs in vivo.
Topics: Adaptive Immunity; Animals; Arginine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Immunity, Innate; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Myeloid-Derived Suppressor Cells; Real-Time Polymerase Chain Reaction | 2016 |
Interleukin-22 ameliorates acute severe pancreatitis-associated lung injury in mice.
Topics: Acute Disease; Acute Lung Injury; Amylases; Animals; Arginine; bcl-X Protein; Biomarkers; Blotting, Western; Disease Models, Animal; Gene Expression Regulation; Interleukin-22; Interleukins; Lung; Male; Mice, Inbred BALB C; Pancreas; Pancreatitis; Peroxidase; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Real-Time Polymerase Chain Reaction; Receptors, Interleukin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Severity of Illness Index; Signal Transduction; STAT3 Transcription Factor; Time Factors | 2016 |
Experimental Models in Syrian Golden Hamster Replicate Human Acute Pancreatitis.
Topics: Amylases; Animals; Arginine; Ceruletide; Disease Models, Animal; Ethanol; Fatty Acids; Humans; Injections; Mesocricetus; Pancreatitis; Peroxidase; Severity of Illness Index; Taurocholic Acid | 2016 |
Long-Term Chronic Intermittent Hypobaric Hypoxia in Rats Causes an Imbalance in the Asymmetric Dimethylarginine/Nitric Oxide Pathway and ROS Activity: A Possible Synergistic Mechanism for Altitude Pulmonary Hypertension?
Topics: Altitude Sickness; Amidohydrolases; Animals; Arginine; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Pulmonary Circulation; Rats; Rats, Wistar; Signal Transduction; Time Factors; Vascular Resistance | 2016 |
MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginine; Choline; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Male; Methionine; Rats; Rats, Wistar | 2016 |
Atorvastatin attenuates the antinociceptive tolerance of morphine via nitric oxide dependent pathway in male mice.
Topics: Animals; Arginine; Atorvastatin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Opioid-Related Disorders; Pain Measurement; Pain Threshold; Signal Transduction | 2016 |
Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Female; Hyperalgesia; Ibuprofen; MicroRNAs; Muscles; Nitric Oxide; Peripheral Nervous System Diseases; Rats, Wistar; Skin; Spinal Cord; Streptozocin; Up-Regulation | 2016 |
Protein arginine methylation facilitates KCNQ channel-PIP2 interaction leading to seizure suppression.
Topics: Animals; Arginine; Disease Models, Animal; Epilepsy; KCNQ Potassium Channels; Methylation; Mice, Inbred C57BL; Phosphatidylinositol 4,5-Diphosphate; Protein Binding; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases | 2016 |
Increasing the availability of l-arginine and nitric oxide increases sensitivity of nitrous oxide (N2O)-insensitive inbred mice to N2O-induced antinociception.
Topics: Abdominal Pain; Analgesics; Analysis of Variance; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitrous Oxide; Pain Threshold; Species Specificity | 2016 |
The modulatory effect of nitric oxide in pro- and anti-convulsive effects of vasopressin in PTZ-induced seizures threshold in mice.
Topics: Animals; Anticonvulsants; Antidiuretic Hormone Receptor Antagonists; Arginine; Arginine Vasopressin; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Indoles; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Pyrrolidines; Receptors, Vasopressin; Seizures | 2016 |
Omics to Explore Amyotrophic Lateral Sclerosis Evolution: the Central Role of Arginine and Proline Metabolism.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Disease Models, Animal; Female; Humans; Longitudinal Studies; Male; Metabolomics; Mice, Transgenic; Motor Neurons; Proline; Superoxide Dismutase; Tryptophan | 2017 |
Metabolic determinants of the immune modulatory function of neural stem cells.
Topics: Animals; Arginase; Arginine; Cell Proliferation; Cells, Cultured; Coculture Techniques; Colorimetry; Cytokines; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Immunologic Factors; Lateral Ventricles; Metabolomics; Mice; Neural Stem Cells; Signal Transduction; T-Lymphocytes | 2016 |
Intracerebral Administration of S-Adenosylhomocysteine or S-Adenosylmethionine Attenuates the Increases in the Cortical Extracellular Levels of Dimethylarginines Without Affecting cGMP Level in Rats with Acute Liver Failure.
Topics: Animals; Arginine; Cyclic GMP; Disease Models, Animal; Extracellular Space; Hepatic Encephalopathy; Liver Failure, Acute; Male; Prefrontal Cortex; Protein-Arginine N-Methyltransferases; Rats, Sprague-Dawley; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Signal Transduction | 2017 |
Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model.
Topics: Animals; Arginine; Cecum; Cell Movement; Cells, Cultured; Citrulline; Disease Models, Animal; Extracellular Traps; Histones; Humans; Hydrolases; Male; Mice; Mice, Inbred C57BL; Neutrophils; Ornithine; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 4; Sepsis | 2017 |
Tetrahydrobiopterin Supplementation Improves Phenylalanine Metabolism in a Murine Model of Severe Malaria.
Topics: Animals; Aorta; Arginine; Biopterins; Brain; Disease Models, Animal; Humans; Malaria; Mice; Mice, Inbred C57BL; Nitric Oxide; Phenylalanine; Plasmodium berghei | 2016 |
The Effect of l-Arginine on Dural Healing After Experimentally Induced Dural Defect in a Rat Model.
Topics: Animals; Arginine; Cerebrospinal Fluid Leak; Collagen; Disease Models, Animal; Dura Mater; Male; Rats; Rats, Wistar; Severity of Illness Index; Statistics, Nonparametric; Wound Healing | 2017 |
Prophylactic Administration of Silybin Ameliorates L-Arginine-Induced Acute Pancreatitis.
Topics: Acute Disease; Animals; Antioxidants; Arginine; Disease Models, Animal; Female; Oxidative Stress; Pancreatitis; Rats; Rats, Wistar; Silybin; Silymarin | 2016 |
Oral or topical administration of L-arginine changes the expression of TGF and iNOS and results in early wounds healing.
Topics: Administration, Oral; Administration, Topical; Animals; Arginine; Collagen; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Immunocompromised Host; Inflammation; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Surgical Wound; Transforming Growth Factor beta; Wound Healing; Wounds and Injuries | 2016 |
The Presence of the Neuronal Nitric Oxide Synthase Isoform in the Intervertebral Disk.
Topics: Animals; Arginine; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Immunohistochemistry; Intervertebral Disc; Intervertebral Disc Degeneration; Magnetic Resonance Imaging; Male; Nitric Oxide Synthase Type I; Polymerase Chain Reaction; Rats, Wistar; RNA, Messenger; RNA, Small Interfering; Sacrococcygeal Region | 2017 |
Systemic delivery of small interfering RNA targeting nuclear factor κB in mice with collagen-induced arthritis using arginine-histidine-cysteine based oligopeptide-modified polymer nanomicelles.
Topics: Animals; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen; Cysteine; Cytokines; Disease Models, Animal; Histidine; Inflammation; Male; Mice; Mice, Inbred DBA; Micelles; Nanoparticles; NF-kappa B; Oligopeptides; Polymers; RNA, Messenger; RNA, Small Interfering; Synovial Membrane; Synoviocytes; Transcription Factor RelA | 2016 |
Neovascularization and functional recovery after intracerebral hemorrhage is conditioned by the Tp53 Arg72Pro single-nucleotide polymorphism.
Topics: Aged; Aged, 80 and over; Animals; Apoptosis; Arginine; Bone Marrow Cells; Brain; Cells, Cultured; Cerebral Hemorrhage; Chemokine CXCL12; Collagenases; Disease Models, Animal; Endothelial Progenitor Cells; Female; Humans; Male; Mice; Mice, Transgenic; Middle Aged; Neovascularization, Physiologic; Polymorphism, Single Nucleotide; Proline; Tomography, X-Ray Computed; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2017 |
Participation of hippocampal nitric oxide synthase and soluble guanylate cyclase in the modulation of behavioral responses elicited by the rat forced swimming test.
Topics: Amidines; Animals; Arginine; Benzylamines; Disease Models, Animal; Hippocampus; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Oxadiazoles; Rats; Rats, Wistar; Soluble Guanylyl Cyclase; Stress, Psychological; Swimming; Time Factors | 2017 |
Dietary arginine silicate inositol complex inhibits periodontal tissue loss in rats with ligature-induced periodontitis.
Topics: Animals; Arginine; Diet; Disease Models, Animal; Drug Combinations; Female; Gingiva; Inositol; Ligation; Periodontitis; Rats; Rats, Sprague-Dawley; Silicates | 2016 |
Nilotinib, a tyrosine kinase inhibitor exhibits protection against acute pancreatitis-induced lung and liver damage in rats.
Topics: Acute Disease; Amylases; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Biomarkers; Cytoprotection; Disease Models, Animal; Lipase; Liver Diseases; Lung Injury; Male; NF-kappa B; Nitrates; Nitrites; Pancreatitis; Protein Kinase Inhibitors; Pyrimidines; Rats, Sprague-Dawley; Time Factors; Transforming Growth Factor beta1 | 2017 |
Midkine is overexpressed in acute pancreatitis and promotes the pancreatic recovery in L-arginine-induced acute pancreatitis in mice.
Topics: Acinar Cells; Acute Disease; alpha-Amylases; Animals; Arginine; Cytokines; Disease Models, Animal; Fibrosis; Gene Expression; Male; Mice, Inbred C57BL; Midkine; Pancreas; Pancreatitis; Proliferating Cell Nuclear Antigen; Recombinant Proteins; Regeneration; Up-Regulation | 2017 |
Influence of Volatile Anesthesia on the Release of Glutamate and other Amino Acids in the Nucleus Accumbens in a Rat Model of Alcohol Withdrawal: A Pilot Study.
Topics: Amino Acids; Anesthesia, Inhalation; Animals; Arginine; Aspartic Acid; Desflurane; Disease Models, Animal; Feeding Behavior; gamma-Aminobutyric Acid; Glutamic Acid; Isoflurane; Male; Microdialysis; Nucleus Accumbens; Pilot Projects; Rats, Wistar; Substance Withdrawal Syndrome; Time Factors; Volatilization | 2017 |
Protective effect of tanshinone IIA against cardiac hypertrophy in spontaneously hypertensive rats through inhibiting the Cys-C/Wnt signaling pathway.
Topics: Abietanes; Animals; Arginine; Cardiomegaly; Cardiovascular Agents; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type III; Cystatin C; Disease Models, Animal; Hypertension; Male; Myocardium; NADPH Oxidase 4; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Troponin I; Wnt Signaling Pathway | 2017 |
Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis.
Topics: Animals; Arginine; Ascorbic Acid; Colitis; Cytokines; Dextran Sulfate; Dietary Supplements; Disease Models, Animal; Fatty Acids, Omega-3; Intestines; Leukocytes; Mice; Mice, Inbred C57BL; Oxidative Stress; Reactive Oxygen Species; Tight Junctions | 2017 |
Modulation of mTOR signaling as a strategy for the treatment of Pompe disease.
Topics: Animals; Arginine; Disease Models, Animal; Glycogen Storage Disease Type II; Mice; Mice, Knockout; Muscles; Signal Transduction; TOR Serine-Threonine Kinases; Treatment Outcome | 2017 |
Repetitive ischemia increases myocardial dimethylarginine dimethylaminohydrolase 1 expression.
Topics: Amidohydrolases; Animals; Arginine; Cell Hypoxia; Cells, Cultured; Collateral Circulation; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Endothelial Cells; Humans; Interleukin-1beta; Myocardial Ischemia; Myocardium; Neovascularization, Physiologic; Nitric Oxide Synthase Type II; Protein-Arginine N-Methyltransferases; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A | 2017 |
Reduced local input to fast-spiking interneurons in the somatosensory cortex in the GABA
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Arginine; Disease Models, Animal; Epilepsy, Absence; Female; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Point Mutation; Receptors, GABA-A; Somatosensory Cortex | 2017 |
Fish oil prevents rodent anxious states comorbid with diabetes: A putative involvement of nitric oxide modulation.
Topics: Amygdala; Animals; Anxiety; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Fish Oils; Hippocampus; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Periaqueductal Gray; Rats; Rats, Wistar; Streptozocin | 2017 |
Arginine Is a Critical Substrate for the Pathogenesis of
Topics: Animals; Anti-Bacterial Agents; Arginine; Burns; Disease Models, Animal; Mice; Pseudomonas aeruginosa; Pseudomonas Infections; Survival Analysis; Treatment Outcome; Virulence; Wound Infection | 2017 |
Time-course changes of nLDL-induced erectile dysfunction.
Topics: Animals; Arginine; Disease Models, Animal; Endothelium, Vascular; Erectile Dysfunction; Hyperlipidemias; Lipoproteins, LDL; Male; Nitric Oxide Synthase Type III; Rats, Wistar; Time Factors | 2017 |
Novel microspheres reduce the formation of deep venous thrombosis and repair the vascular wall in a rat model.
Topics: Animals; Arginine; Blood Coagulation; Disease Models, Animal; Drug Delivery Systems; P-Selectin; Rats; Rats, Sprague-Dawley; Venae Cavae; Venous Thrombosis | 2017 |
Rosiglitazone improves aortic arginine transport, through inhibition of PKCalpha, in uremic rats.
Topics: Animals; Aorta; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Disease Models, Animal; Hypoglycemic Agents; Kidney Failure, Chronic; Male; Nitric Oxide; Protein Kinase C-alpha; Rats; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Uremia | 2008 |
Arginine-induced pancreatitis: involvement of the autonomic nervous system?
Topics: Acute Disease; Amylases; Animals; Arginine; Collagen; Disease Models, Animal; Enzyme Activation; Fibrosis; Lung Diseases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pancreas; Pancreatitis; Peroxidase; Trypsin | 2008 |
Arginine transport is augmented, through modulation of cationic amino acid transporter-1, in obstructive uropathy in rats.
Topics: Animals; Arginase; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Disease Models, Animal; Gene Expression Regulation; Kidney Diseases; Rats; RNA, Messenger | 2008 |
Time-dependent alterations in serum NO concentration after oral administration of L-arginine, L-NAME, and allopurinol in intestinal ischemia/reperfusion.
Topics: Administration, Oral; Allopurinol; Animals; Arginine; Catalase; Disease Models, Animal; Enzyme Inhibitors; Intestinal Mucosa; Intestines; Male; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Xanthine Oxidase | 2008 |
Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia.
Topics: Amidohydrolases; Animals; Arginine; Carotid Arteries; Cell Line; Cystathionine beta-Synthase; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Folic Acid; Gene Expression Regulation, Enzymologic; Homocysteine; Hyperhomocysteinemia; Liver; Methionine; Methylation; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; RNA, Messenger; Vasodilation; Vasodilator Agents | 2008 |
L-Arginine prevents metabolic effects of high glucose in diabetic mice.
Topics: Aldehyde Reductase; Animals; Aortitis; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glutathione; Heart Diseases; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Phosphorylation; Polymers; Protein Kinase C; Protein Kinase C beta; Sorbitol; Superoxides | 2008 |
Regulation of endothelial nitric oxide synthase and postnatal angiogenesis by Rac1.
Topics: Aminoquinolines; Animals; Arginine; Cationic Amino Acid Transporter 1; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Hindlimb; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Pyrimidines; rac1 GTP-Binding Protein; Receptor, TIE-2; Vasodilation | 2008 |
Impaired glucose-stimulated insulin secretion in the GK rat is associated with abnormalities in islet nitric oxide production.
Topics: Animals; Arginine; Colforsin; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2008 |
The prevention of endothelial dysfunction through endothelial cell apoptosis inhibition in a hypercholesterolemic rabbit model: the effect of L-arginine supplementation.
Topics: Animals; Aorta; Apoptosis; Arginine; Atherosclerosis; Cell Count; Cholesterol; Dietary Supplements; Disease Models, Animal; Endothelial Cells; Hypercholesterolemia; In Situ Nick-End Labeling; Male; Nitrites; Rabbits | 2008 |
Leptin-induced endothelial dysfunction in obesity.
Topics: Animals; Arginine; Biosensing Techniques; Calcium; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Humans; Ionophores; Leptin; Male; Mice; Mice, Inbred C57BL; Nanotechnology; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Obesity; Peroxynitrous Acid; Reactive Oxygen Species; Superoxides; Time Factors | 2008 |
Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome.
Topics: Animals; Arginine; Basal Metabolism; Blood Glucose; Blood Pressure; Body Weight; Chromosome Mapping; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretion; Islets of Langerhans; Lipids; Obesity; Quantitative Trait Loci; Rats; Rats, Inbred Strains | 2008 |
Role of nitric oxide in the anticonvulsive effect of progesterone.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovariectomy; Pentylenetetrazole; Progesterone; Seizures; Time Factors | 2008 |
Y1 receptor knockout increases nociception and prevents the anti-allodynic actions of NPY.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arginine; Behavior, Animal; Disease Models, Animal; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Neuropeptide Y; Pain; Pain Measurement; Receptors, Neuropeptide Y; Sciatic Neuropathy | 2008 |
L-arginine supplementation influenced nitrite but not nitrate and total nitrite in rabbit model of hypercholesterolemia.
Topics: Animals; Arginine; Cholesterol; Dietary Supplements; Disease Models, Animal; Hypercholesterolemia; Male; Nitrates; Nitrites; Rabbits | 2008 |
Involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of tramadol in the rat forced swimming test.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Male; Nitric Oxide; Rats; Rats, Wistar; Signal Transduction; Swimming; Tramadol | 2008 |
Identification of a missense mutation in the bovine ATP2A1 gene in congenital pseudomyotonia of Chianina cattle: an animal model of human Brody disease.
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Disease Models, Animal; DNA Mutational Analysis; Female; Humans; Isaacs Syndrome; Male; Molecular Sequence Data; Mutation, Missense; Myotonia Congenita; Pedigree; Physical Conditioning, Animal; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2008 |
Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocin-induced experimental hyperglycemia.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Esophagus; Glutathione Peroxidase; Glycosylation; Hyperglycemia; Indomethacin; Lipid Peroxidation; Male; Malondialdehyde; Mucous Membrane; Nitric Oxide; Nitrosation; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin | 2008 |
Nerve stimulation induced overflow of neuropeptide Y and modulation by angiotensin II in spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Age Factors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Blood Pressure; Captopril; Disease Models, Animal; Electric Stimulation; Hypertension; Imidazoles; Mesenteric Arteries; Neuropeptide Y; Prazosin; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 2; Receptors, Adrenergic, alpha-2; Receptors, Neuropeptide Y; Splanchnic Circulation; Sympathetic Nervous System | 2008 |
Protective effects of L-arginine against ischemia-reperfusion injury in non-heart beating rat liver graft.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Disease Models, Animal; Endothelins; Female; Injections, Intravenous; Liver; Liver Transplantation; Male; Microscopy, Electron, Transmission; Nitric Oxide; Organ Preservation; Protective Agents; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Warm Ischemia | 2008 |
Prophylactic role of oral L-arginine on histological and contractile changes in a rat chronic bladder injury model.
Topics: Administration, Oral; Adrenergic beta-Agonists; Animals; Arginine; Carbachol; Cholinergic Agonists; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Potassium; Protamines; Rats; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder Diseases; Urothelium | 2008 |
Variance of DDAH/PRMT/ADMA pathway in atrial fibrillation dogs.
Topics: Amidohydrolases; Animals; Arginine; Atrial Fibrillation; Disease Models, Animal; Dogs; Down-Regulation; Endothelium; Female; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein-Arginine N-Methyltransferases; Thrombosis; Up-Regulation | 2008 |
Involvement of asymmetric dimethylarginine (ADMA) in tubulointerstitial ischaemia in the early phase of diabetic nephropathy.
Topics: Adenoviridae; Amidohydrolases; Animals; Arginine; Diabetic Nephropathies; Disease Models, Animal; Genetic Vectors; Ischemia; Kidney; Male; Nephritis, Interstitial; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2009 |
Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin.
Topics: Animals; Arginase; Arginine; Asthma; Breath Tests; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibitors; Lung; Lung Compliance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Ovalbumin; Pneumonia; Up-Regulation | 2009 |
Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice.
Topics: Analysis of Variance; Anesthetics; Animals; Arginine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Histidine; Hyperalgesia; Indoles; Male; Mice; Mice, Mutant Strains; Motor Activity; Physical Stimulation; Point Mutation; Protein Subunits; Pyrroles; Receptors, GABA-A | 2009 |
Beneficial effects of rutin and L-arginine coadministration in a rat model of liver ischemia-reperfusion injury.
Topics: Alanine Transaminase; Animals; Antioxidants; Arginine; Aspartate Aminotransferases; Disease Models, Animal; Drug Therapy, Combination; Heme Oxygenase (Decyclizing); Lipid Peroxidation; Liver Diseases; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Rutin; Sulfhydryl Compounds | 2009 |
A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy.
Topics: Animals; Animals, Newborn; Arginine; Biophysics; Calcium Channels, T-Type; Cell Line, Transformed; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Exons; Humans; In Vitro Techniques; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Point Mutation; Proline; Protein Isoforms; Protein Structure, Tertiary; Rats; Rats, Transgenic; Seizures; Transfection | 2009 |
Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.
Topics: Age Factors; Alanine; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Arginine; Axons; Cell Line, Transformed; Denervation; Disease Models, Animal; Electromyography; Humans; Luminescent Proteins; Mice; Mice, Transgenic; Microscopy, Electron, Transmission; Microsomes; Mitochondria; Mitochondrial Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Neuromuscular Junction; Organ Culture Techniques; Peripheral Nerves; Protein Transport; Rats; Subcellular Fractions; Transfection; Tubulin; Wallerian Degeneration | 2009 |
Arginase promotes neointima formation in rat injured carotid arteries.
Topics: Animals; Arginase; Arginine; Boronic Acids; Carotid Artery Injuries; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Hyperplasia; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Rats; Rats, Sprague-Dawley; RNA Interference; RNA, Small Interfering; Time Factors; Tunica Intima; Up-Regulation | 2009 |
Neuropeptide Y fragments derived from neprilysin processing are neuroprotective in a transgenic model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Arginine; Benzazepines; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Genetic Vectors; Humans; Mice; Mice, Transgenic; Neprilysin; Nerve Degeneration; Nerve Growth Factors; Neurons; Neuropeptide Y; Peptide Fragments; Receptors, Neuropeptide Y | 2009 |
Involvement of nitrergic system in the anticonvulsant effect of the cannabinoid CB(1) agonist ACEA in the pentylenetetrazole-induced seizure in mice.
Topics: Analysis of Variance; Animals; Animals, Inbred Strains; Anticonvulsants; Arachidonic Acids; Arginine; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Seizures | 2009 |
Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1.
Topics: Animals; Aorta; Arginine; Atherosclerosis; Atorvastatin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Heme Oxygenase-1; Hemin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipid Peroxidation; Male; Malondialdehyde; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Protoporphyrins; Pyrroles; Rabbits; Simvastatin; Time Factors | 2009 |
Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats.
Topics: Animals; Anticoagulants; Arginine; Blood-Brain Barrier; Brain Edema; Cell Death; Disease Models, Animal; Male; Motor Activity; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Recovery of Function; Subarachnoid Hemorrhage; Sulfonamides; Thrombin | 2009 |
Selective neuronal nitric oxide synthase inhibitors and the prevention of cerebral palsy.
Topics: Animals; Animals, Newborn; Arginine; Behavior, Animal; Blood Pressure; Brain; Cerebral Palsy; Citrulline; Crystallography, X-Ray; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Female; Male; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type I; Pregnancy; Rabbits; Structure-Activity Relationship | 2009 |
Effects of L-arginine and L-lysine mixtures on splenic sympathetic nerve activity and tumor proliferation.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arginine; Carcinoma; Cell Proliferation; Colonic Neoplasms; Disease Models, Animal; Female; Humans; Immune Tolerance; Immunologic Factors; Killer Cells, Natural; Lysine; Male; Mice; Mice, Inbred BALB C; Neoplasms; Neuroimmunomodulation; Rats; Rats, Wistar; Spleen; Sympathetic Nervous System; Treatment Outcome | 2009 |
L-arginine deficiency causes airway hyperresponsiveness after the late asthmatic reaction.
Topics: Animals; Arginase; Arginine; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Guinea Pigs; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Ovalbumin; Perfusion; Peroxynitrous Acid; Polyamines; Polyelectrolytes; Trachea | 2009 |
Spontaneous autoimmunity in mice that carry an IghV partial transgene: a required arginine in VHCDR3.
Topics: Animals; Antibodies, Antinuclear; Arginine; Autoimmunity; B-Lymphocytes; Chromatin; Disease Models, Animal; Kidney; Lupus Erythematosus, Systemic; Mice; Mice, Transgenic; Splenomegaly; Transgenes | 2009 |
Effect of L-arginine on metabolism of polyamines in rat's brain with extrahepatic cholestasis.
Topics: Alkaline Phosphatase; Animals; Arginine; Bilirubin; Brain; Cholestasis, Extrahepatic; Disease Models, Animal; gamma-Glutamyltransferase; Male; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Polyamines; Rats; Rats, Wistar | 2010 |
Altered arginine metabolism in the central nervous system (CNS) of the Cln3-/- mouse model of juvenile Batten disease.
Topics: Animals; Arginine; Brain; Cationic Amino Acid Transporter 1; Cells, Cultured; Citrulline; Disease Models, Animal; Female; Gene Expression; Liver; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Neurons; Nitric Oxide; Nitric Oxide Synthase; Protein Isoforms; RNA, Messenger; Urea | 2009 |
Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction.
Topics: Acetylcysteine; Actin Cytoskeleton; Animals; Antioxidants; Arginine; Biopterins; Disease Models, Animal; Exercise Therapy; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Infarction; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Physical Exertion; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Superoxides; Time Factors; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Pressure; Ventricular Remodeling | 2009 |
Mitochondrial alterations in transgenic mice with an H46R mutant Cu/Zn superoxide dismutase gene.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Arginine; Disease Models, Animal; Histidine; Mice; Mice, Transgenic; Microscopy, Immunoelectron; Mitochondria; Mutation; Spinal Cord; Superoxide Dismutase | 2009 |
Pancreatitis induced in rats by repetitive administration of L-arginine.
Topics: Animals; Arginine; Disease Models, Animal; Injections; Male; Pancreatitis, Chronic; Rats; Rats, Sprague-Dawley | 2009 |
Involvement of asymmetric dimethylarginine (ADMA) in glomerular capillary loss and sclerosis in a rat model of chronic kidney disease (CKD).
Topics: Amidohydrolases; Animals; Arginine; Capillaries; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Humans; Kidney Failure, Chronic; Kidney Glomerulus; Rats | 2009 |
Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin.
Topics: Amyloid; Animals; Animals, Genetically Modified; Arginine; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Islet Amyloid Polypeptide; Islets of Langerhans; Metformin; Pyrazines; Rats; Rats, Sprague-Dawley; Sitagliptin Phosphate; Triazoles | 2009 |
A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation.
Topics: Animals; Animals, Newborn; Arginine; Biophysical Phenomena; Cells, Cultured; Chromosomes, Artificial, Bacterial; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Epilepsy, Generalized; Histidine; Kainic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; RNA, Messenger; Seizures, Febrile; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin | 2009 |
Heme arginate suppresses cardiac lesions and hypertrophy in deoxycorticosterone acetate-salt hypertension.
Topics: Animals; Arginine; Cardiomegaly; Desoxycorticosterone; Disease Models, Animal; Heart; Heart Diseases; Heme; Heme Oxygenase (Decyclizing); Hypertension; Hypertrophy, Left Ventricular; Male; MAP Kinase Kinase 4; Mesoporphyrins; Myocardium; NF-kappa B; Rats; Rats, Sprague-Dawley; Transcription Factor AP-1; Transforming Growth Factor beta | 2009 |
[The study of endothelial dysfunction in animals with experimentally induced deficiency of sex hormones].
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Endothelium, Vascular; Female; Gonadal Steroid Hormones; Hypertension; Middle Cerebral Artery; Nitroglycerin; Rats; Rats, Wistar; Risk Factors; Ultrasonography, Doppler, Transcranial; Vasodilation; Vasodilator Agents | 2009 |
Time course of desflurane-induced preconditioning in rabbits.
Topics: Anesthetics, Inhalation; Animals; Arginine; Desflurane; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Myocardial Infarction; Nitric Oxide Synthase; Rabbits; Random Allocation; Time Factors | 2010 |
Inhibition of natriuretic factors increases blood pressure in rats.
Topics: Amidohydrolases; Animals; Antioxidants; Arginine; Blood Pressure; Buthionine Sulfoximine; Cyclic N-Oxides; Disease Models, Animal; Dopamine; Hypertension; Kidney Tubules, Proximal; Male; Natriuresis; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidants; Oxidative Stress; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Serine; Signal Transduction; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Spin Labels | 2009 |
Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction.
Topics: Amidohydrolases; Animals; Aorta; Arginine; Disease Models, Animal; Endocardium; Heart Ventricles; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein-Arginine N-Methyltransferases; Rats; Rats, Wistar | 2010 |
Raloxifene ameliorates detrimental enzymatic and nonenzymatic collagen cross-links and bone strength in rabbits with hyperhomocysteinemia.
Topics: Animals; Arginine; Bone and Bones; Bone Density; Bone Density Conservation Agents; Collagen; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Glycation End Products, Advanced; Hyperhomocysteinemia; Lysine; Methionine; Osteoporosis; Rabbits; Raloxifene Hydrochloride; Stress, Mechanical | 2010 |
In the rat maximal dentate activation model of partial complex epilepsy, the anticonvulsant activity of levetiracetam is modulated by nitric oxide-active drugs.
Topics: Animals; Anticonvulsants; Arginine; Dentate Gyrus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Epilepsy, Complex Partial; Indazoles; Levetiracetam; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Piracetam; Rats; Rats, Wistar | 2009 |
Pharmacological preconditioning using intraportal infusion of L-arginine protects against hepatic ischemia reperfusion injury.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Caspase 3; Disease Models, Animal; Female; Infusions, Intravenous; Ischemic Preconditioning; Liver; Mitochondria, Liver; Nitric Oxide; Reperfusion Injury; Signal Transduction; Swine; Thiobarbituric Acid Reactive Substances | 2009 |
Arginase II knockout mouse displays a hypertensive phenotype despite a decreased vasoconstrictory profile.
Topics: Analysis of Variance; Animals; Arginase; Arginine; Baroreflex; Blood Flow Velocity; Blood Pressure Determination; Catecholamines; Disease Models, Animal; Female; Heart Function Tests; Hypertension; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Phenotype; Probability; Random Allocation; Sensitivity and Specificity; Urea; Vascular Resistance; Vasoconstriction | 2009 |
Antinociceptive effects of (O-methyl)-N-benzoyl tyramine (riparin I) from Aniba riparia (Nees) Mez (Lauraceae) in mice.
Topics: Acetic Acid; Administration, Oral; Analgesics; Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Formaldehyde; Hot Temperature; Injections, Intraperitoneal; Lauraceae; Male; Mice; Morphine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pain; Pain Measurement; Reaction Time; Time Factors; Tyramine | 2009 |
Pancreatic function of spontaneously diabetic torii rats in pre-diabetic stage.
Topics: Animals; Arginine; Benzoates; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Obesity; Organ Culture Techniques; Pancreas; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tolbutamide | 2009 |
A functional null mutation of SCN1B in a patient with Dravet syndrome.
Topics: Animals; Arginine; Biophysics; Cell Line, Transformed; Cysteine; Disease Models, Animal; DNA Mutational Analysis; Electric Stimulation; Epilepsies, Myoclonic; Female; Green Fluorescent Proteins; Hippocampus; Humans; In Vitro Techniques; Infant; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Molecular; NAV1.1 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Oocytes; Polymorphism, Single Nucleotide; Sodium Channels; Temperature; Transfection; Twins; Voltage-Gated Sodium Channel beta-1 Subunit; Xenopus laevis | 2009 |
Role of neutrophils in arginine-asymmetric dimethylarginine pathway subsequent to endotoxemia.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Guinea Pigs; Lipopolysaccharides; Liver; Male; Neutrophils; Peroxidase; Tyrosine | 2009 |
[Effects of Xuefu Zhuyu decoction on serum asymmetric dimethylarginine in atherosclerosis rabbits].
Topics: Animals; Arginine; Atherosclerosis; Cholesterol; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Male; Rabbits; Random Allocation; Triglycerides | 2009 |
Effects of early enteral nutrition supplemented with arginine on intestinal mucosal immunity in severely burned mice.
Topics: Analysis of Variance; Animals; Arginine; Body Weight; Burns; Cytokines; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunity, Mucosal; Immunoglobulin A; Intestinal Mucosa; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Peyer's Patches; Severity of Illness Index | 2010 |
Early excitability changes in lumbar motoneurons of transgenic SOD1G85R and SOD1G(93A-Low) mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Biophysical Phenomena; Biophysics; Calcium Channel Blockers; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; In Vitro Techniques; Interneurons; Lumbosacral Region; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nifedipine; Patch-Clamp Techniques; Riluzole; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1 | 2009 |
The effect of L-arginine and L-NAME on pentylenetetrazole induced seizures in ovariectomized rats, an in vivo study.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Enzyme Inhibitors; Female; NG-Nitroarginine Methyl Ester; Ovariectomy; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2009 |
Decreased arginine methylation and myelin alterations in arsenic exposed rats.
Topics: Analysis of Variance; Animals; Arginine; Arsenic; Arsenic Poisoning; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Male; Methylation; Myelin Sheath; Organ Size; Rats; Rats, Wistar; Time Factors | 2010 |
In vivo renal arginine release is impaired throughout development of chronic kidney disease.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Chronic Disease; Citrulline; Disease Models, Animal; Kidney Cortex; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2010 |
The effect of L-arginine on pneumocyte apoptosis in lung ischemia/reperfusion injury in rabbits.
Topics: Alveolar Epithelial Cells; Animals; Apoptosis; Arginine; Disease Models, Animal; Female; Lung; Lung Injury; Male; Rabbits; Reperfusion Injury | 2009 |
Thrombin inhibition in subarachnoid hemorrhage.
Topics: Animals; Arginine; Disease Models, Animal; Humans; Pipecolic Acids; Platelet Aggregation Inhibitors; Subarachnoid Hemorrhage; Sulfonamides; Thrombin | 2009 |
Seizure susceptibility alteration through 5-HT(3) receptor: modulation by nitric oxide.
Topics: Animals; Anticonvulsants; Arginine; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Granisetron; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Piperidines; Receptors, Serotonin, 5-HT3; Seizures; Serotonin Antagonists | 2010 |
Venlafaxine involves nitric oxide modulatory mechanism in experimental model of chronic behavior despair in mice.
Topics: Animals; Antidepressive Agents, Second-Generation; Anxiety; Arginine; Caffeine; Central Nervous System Stimulants; Chronic Disease; Cyclohexanols; Depressive Disorder; Disease Models, Animal; Enzyme Inhibitors; Male; Methylene Blue; Mice; Mice, Inbred Strains; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Random Allocation; Swimming; Venlafaxine Hydrochloride | 2010 |
Endothelial nitric oxide synthase activity involves in the protective effect of ascorbic acid against penicillin-induced epileptiform activity.
Topics: Analysis of Variance; Animals; Antioxidants; Arginine; Ascorbic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Free Radical Scavengers; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Penicillins; Rats; Rats, Wistar | 2010 |
[Effect of L-arginine on pro- and antioxidant status of the rat vessels and lungs in experimental rhabdomyolysis].
Topics: Animals; Antioxidants; Arginine; Blood Vessels; Catalase; Disease Models, Animal; Glycerol; Heme; Heme Oxygenase (Decyclizing); Lung; Male; Nitric Oxide Donors; Protein Carbonylation; Rats; Rats, Wistar; Rhabdomyolysis; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2009 |
Mutant SOD1 knockdown in all cell types ameliorates disease in G85R SOD1 mice with a limited additional effect over knockdown restricted to motor neurons.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Disease Models, Animal; Estrogen Antagonists; Glycine; Humans; Mice; Mice, Transgenic; Motor Neurons; Mutation; RNA, Messenger; Spinal Cord; Superoxide Dismutase; Superoxide Dismutase-1; Tamoxifen; Time Factors | 2010 |
Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats.
Topics: Animals; Apoptosis; Arginine; Cell Proliferation; Disease Models, Animal; Hydrogen; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley; Sodium Chloride | 2010 |
A crucial role of nitric oxide in acute lung injury secondary to the acute necrotizing pancreatitis.
Topics: Acute Lung Injury; Animals; Arginine; Bronchoalveolar Lavage Fluid; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Inflammation Mediators; Injections, Intraperitoneal; Lung; Macrophages, Alveolar; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pancreatitis, Acute Necrotizing; Peroxidase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Taurocholic Acid; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2010 |
Reduced caloric intake during endotoxemia reduces arginine availability and metabolism.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Endotoxins; Energy Intake; Escherichia coli; Lactic Acid; Lipopolysaccharides; Nitric Oxide; Protein-Energy Malnutrition; Proteins; Pyruvic Acid; Random Allocation; Swine | 2010 |
Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma.
Topics: Animals; Arginase; Arginine; Asthma; Blotting, Western; Bronchial Hyperreactivity; Disease Models, Animal; Eosinophilia; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress | 2010 |
Does pharmacological dose of parenteral arginine have beneficial effect in rats with sub-acute peritonitis?
Topics: Animals; Anti-Inflammatory Agents; Arginine; Disease Models, Animal; Male; Parenteral Nutrition, Total; Peritonitis; Rats; Rats, Wistar | 2010 |
Melatonin prevents increased asymmetric dimethylarginine in young rats with bile duct ligation.
Topics: Amidohydrolases; Analysis of Variance; Animals; Arginine; Bile Ducts; Cholestasis, Intrahepatic; Disease Models, Animal; Immunohistochemistry; Kidney; Liver; Male; Melatonin; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2010 |
Cardiovascular effects of arginase inhibition in spontaneously hypertensive rats with fully developed hypertension.
Topics: Animals; Aorta; Arginase; Arginine; Blood Pressure; Cardiovascular Agents; Carotid Arteries; Collagen; Compliance; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fibrosis; Heart Diseases; Hypertension; Male; Membrane Proteins; Mesenteric Arteries; Myocardium; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2010 |
Involvement of nitric oxide-cGMP pathway in the anticonvulsant effects of lithium chloride on PTZ-induced seizure in mice.
Topics: Animals; Anticonvulsants; Arginine; Convulsants; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Indazoles; Injections, Intraperitoneal; Lithium Chloride; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Phosphodiesterase Inhibitors; Piperazines; Purines; Seizures; Sildenafil Citrate; Sulfones; Treatment Outcome | 2010 |
Direct inhibition of arginase attenuated airway allergic reactions and inflammation in a Dermatophagoides farinae-induced NC/Nga mouse model.
Topics: Allergens; Animals; Antigens, Dermatophagoides; Arginase; Arginine; Asthma; Bronchial Hyperreactivity; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Humans; Isoenzymes; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Tyrosine | 2010 |
Heme arginate therapy enhanced adiponectin and atrial natriuretic peptide, but abated endothelin-1 with attenuation of kidney histopathological lesions in mineralocorticoid-induced hypertension.
Topics: Adiponectin; Animals; Arginine; Atrial Natriuretic Factor; Blood Pressure; Blotting, Western; Desoxycorticosterone; Disease Models, Animal; Endothelin-1; Heme; Heme Oxygenase (Decyclizing); Hypertension; Kidney; Kidney Diseases; Male; Mineralocorticoids; Rats; Rats, Sprague-Dawley | 2010 |
Rosiglitazone promotes pancreatic regeneration in experimental model of acute pancreatitis.
Topics: Acute Disease; Animals; Arginine; Disease Models, Animal; DNA; Female; Male; Pancreatitis; PPAR gamma; Rats; Rats, Wistar; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Severity of Illness Index; Sincalide; Thiazolidinediones; Time Factors | 2011 |
Role of nitric oxide in ginsenoside Rg(1)-induced protection against left ventricular hypertrophy produced by abdominal aorta coarctation in rats.
Topics: Abdomen; Animals; Aortic Coarctation; Arginine; Atrial Natriuretic Factor; Cardiovascular Agents; Disease Models, Animal; Endothelium; Ginsenosides; Heart Ventricles; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Panax; Phytotherapy; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2010 |
Intravitreal l-Arginine injection reverses the retinal arteriolar vasoconstriction that occurs after experimental acute branch retinal vein occlusion.
Topics: Animals; Arginine; Arterioles; Blood Pressure; Disease Models, Animal; Injections; Microinjections; Retinal Artery; Retinal Vein Occlusion; Swine; Swine, Miniature; Vasoconstriction; Vasodilation; Vasodilator Agents; Vitreous Body | 2010 |
Agmatine enhances the anticonvulsant effect of lithium chloride on pentylenetetrazole-induced seizures in mice: Involvement of L-arginine/nitric oxide pathway.
Topics: Agmatine; Analysis of Variance; Animals; Antidepressive Agents; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Indazoles; Lithium Chloride; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction | 2010 |
Increased inducible nitric oxide synthase and arginase II expression in heart failure: no net nitrite/nitrate production and protein S-nitrosylation.
Topics: Animals; Arginase; Arginine; Blotting, Western; Cardiac Pacing, Artificial; Disease Models, Animal; Enzyme Inhibitors; Heart Failure; Heart Rate; Imines; Male; Microscopy, Confocal; Myocardial Contraction; Myocardium; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitrites; Protein Processing, Post-Translational; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stroke Volume; Superoxides; Up-Regulation; Ventricular Function, Left | 2010 |
The role of the DDAH-ADMA pathway in the protective effect of resveratrol analog BTM-0512 on gastric mucosal injury.
Topics: Amidohydrolases; Animals; Anti-Ulcer Agents; Arginine; Disease Models, Animal; Ethanol; Hydroxyl Radical; Male; Molecular Structure; Nitric Oxide; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Stomach Ulcer; Superoxides | 2010 |
Simvastatin improves epithelial dysfunction and airway hyperresponsiveness: from asymmetric dimethyl-arginine to asthma.
Topics: Airway Remodeling; Animals; Arginine; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Disease Models, Animal; Epithelial Cells; Epithelium; Lung; Male; Mice; Mice, Inbred BALB C; Mucus; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrosation; Pneumonia; Simvastatin; Stress, Physiological | 2011 |
Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy.
Topics: Animals; Arginine; Behavior, Animal; Butyrates; Disease Models, Animal; Drug Therapy, Combination; Female; Gene Expression Profiling; Gene Expression Regulation; Heart; Mice; Mice, Inbred mdx; Muscles; Muscular Dystrophy, Duchenne; Prednisone; RNA, Messenger; Time Factors; Utrophin | 2010 |
The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginase; Arginine; Asthma; Bleomycin; Collagen; Cytokines; Disease Models, Animal; Inflammation Mediators; Interleukin-4; Lung; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Ovalbumin; Pulmonary Fibrosis; RNA, Messenger; STAT6 Transcription Factor; Up-Regulation | 2010 |
Evaluation of anti-leishmanial activity by induction of nitric oxide and inhibition of prostaglandin in Balb/c mice infected with Leishmania major.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Indomethacin; Leishmania major; Leishmaniasis, Cutaneous; Liver; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Prostaglandin Antagonists; Spleen; Survival Rate | 2009 |
Involvement of nitric oxide in a rat model of carrageenin-induced pleurisy.
Topics: Animals; Antioxidants; Arginine; Carrageenan; Disease Models, Animal; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Pleurisy; Rats; Rats, Wistar; Thiourea | 2010 |
Polyamines Impair Immunity to Helicobacter pylori by Inhibiting L-Arginine Uptake Required for Nitric Oxide Production.
Topics: Animals; Arginine; Cationic Amino Acid Transporter 2; Cells, Cultured; Disease Models, Animal; Gastric Mucosa; Gastritis; Gene Expression Regulation; Helicobacter Infections; Helicobacter pylori; Humans; Immunity, Cellular; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Ornithine Decarboxylase; Polyamines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Spermine | 2010 |
Tissue stiffness induced by prolonged immobilization of the rat knee joint and relevance of AGEs (pentosidine).
Topics: Animals; Arginine; Contracture; Cross-Linking Reagents; Disease Models, Animal; Extracellular Matrix; Glycation End Products, Advanced; Hindlimb Suspension; Knee Joint; Lysine; Male; Range of Motion, Articular; Rats; Rats, Sprague-Dawley; Time Factors | 2010 |
Protective effect of desipramine, venlafaxine and trazodone against experimental animal model of transient global ischemia: possible involvement of NO-cGMP pathway.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Brain; Catalase; Cyclic GMP; Cyclohexanols; Desipramine; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Glutathione; Ischemic Attack, Transient; Lipid Peroxidation; Mice; Models, Biological; Nitric Oxide; Signal Transduction; Trazodone; Venlafaxine Hydrochloride | 2010 |
Nitric oxide pros and cons: The role of L-arginine, a nitric oxide precursor, and idebenone, a coenzyme-Q analogue in ameliorating cerebral hypoxia in rat.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Arginine; Brain; Catalase; Creatine Kinase; Disease Models, Animal; Drug Administration Schedule; Drug Combinations; Gliosis; Hemoglobins; Hypoxia, Brain; L-Lactate Dehydrogenase; Male; Nervous System Diseases; Neurons; Nitrates; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Superoxide Dismutase; Time Factors; Ubiquinone | 2010 |
D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cytokines; Disease Models, Animal; Disease Outbreaks; Female; Hemagglutinin Glycoproteins, Influenza Virus; Humans; Inflammation Mediators; Influenza A Virus, H1N1 Subtype; Influenza, Human; Leucine; Lung; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; N-Acetylneuraminic Acid; Receptors, Virus; Time Factors; Virulence | 2010 |
Short-term specialized enteral diet fails to attenuate malnutrition impairment of experimental open wound acute healing.
Topics: Animals; Antioxidants; Arginine; Collagen; Disease Models, Animal; Enteral Nutrition; Fibroblasts; Food, Formulated; Gene Expression; Inflammation; Male; Malnutrition; Rats; Rats, Inbred Lew; Skin; Wound Healing; Wounds, Penetrating | 2010 |
Early administration of L-arginine in experimental acute spinal cord injury impairs long-term motor function recovery.
Topics: Animals; Arginine; Disease Models, Animal; Female; Follow-Up Studies; Injections, Intravenous; Locomotion; Rats; Rats, Long-Evans; Recovery of Function; Spinal Cord Injuries; Time Factors; Treatment Outcome | 2011 |
Vascular arginase contributes to arteriolar endothelial dysfunction in a rat model of hemorrhagic shock.
Topics: Animals; Arginase; Arginine; Blood Flow Velocity; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Male; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Risk Factors; Shock, Hemorrhagic; Vascular Resistance | 2010 |
Two hypomorphic alleles of mouse Ass1 as a new animal model of citrullinemia type I and other hyperammonemic syndromes.
Topics: Alleles; Animals; Arginine; Argininosuccinate Synthase; Blotting, Western; Cell Movement; Cerebellum; Citrullinemia; Developmental Disabilities; Disease Models, Animal; Female; Growth Disorders; Humans; Hyperammonemia; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Mutation, Missense; Nitric Oxide; Phenotype; Sodium Benzoate; Syndrome | 2010 |
Somatic hypermutation as a generator of antinuclear antibodies in a murine model of systemic autoimmunity.
Topics: Amino Acid Substitution; Animals; Antibodies, Antinuclear; Arginine; B-Lymphocytes; Complementarity Determining Regions; Disease Models, Animal; Genes, Immunoglobulin; Lupus Erythematosus, Systemic; Mice; Recombination, Genetic; Somatic Hypermutation, Immunoglobulin | 2010 |
L-citrulline attenuates arrested alveolar growth and pulmonary hypertension in oxygen-induced lung injury in newborn rats.
Topics: Animals; Animals, Newborn; Arginine; Bronchopulmonary Dysplasia; Citrulline; Disease Models, Animal; Humans; Hypertension, Pulmonary; Infant, Newborn; Lung; Lung Injury; Nitric Oxide; Pulmonary Alveoli; Rats | 2010 |
Argatroban administration reduces leukocyte adhesion and improves capillary perfusion within the intestinal microcirculation in experimental sepsis.
Topics: Animals; Anticoagulants; Arginine; Blood Pressure; Capillaries; Cell Adhesion; Disease Models, Animal; Heart Rate; Intestines; Leukocytes; Male; Microcirculation; Microscopy, Video; Myography; Pipecolic Acids; Rats; Rats, Inbred Lew; Sepsis; Splanchnic Circulation; Sulfonamides; Time Factors; Vasodilation | 2010 |
Simultaneous determination of guanidinosuccinic acid and guanidinoacetic acid in urine using high performance liquid chromatography/tandem mass spectrometry.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycine; Guanidines; Homoarginine; Male; Mice; Mice, Inbred C57BL; Succinates; Tandem Mass Spectrometry | 2010 |
L-arginine reduces mitochondrial dysfunction and airway injury in murine allergic airway inflammation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine Triphosphate; Animals; Apoptosis; Arginine; Asthma; Bronchi; Cytosol; Deoxyguanosine; Disease Models, Animal; DNA Damage; Electron Transport Complex IV; Immunohistochemistry; In Situ Nick-End Labeling; Lung; Male; Mice; Mice, Inbred BALB C; Mitochondria; Ovalbumin; Respiratory System | 2010 |
Plasma miR-216a as a potential marker of pancreatic injury in a rat model of acute pancreatitis.
Topics: Amylases; Animals; Arginine; Biomarkers; Disease Models, Animal; Humans; Lipase; Male; MicroRNAs; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley | 2010 |
C-terminus of heat shock protein 70-interacting protein-dependent GTP cyclohydrolase I degradation in lambs with increased pulmonary blood flow.
Topics: Animals; Anthracenes; Arginine; Blood Flow Velocity; Disease Models, Animal; Female; GTP Cyclohydrolase; Heart Defects, Congenital; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Lung; Nitric Oxide; Nitric Oxide Synthase; Propane; Proteasome Endopeptidase Complex; Sheep | 2011 |
Involvement of the nitric oxide pathway in the anticonvulsant effect of tramadol on pentylenetetrazole-induced seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; Mice, Inbred Strains; Naloxone; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Seizures; Signal Transduction; Time Factors; Tramadol | 2010 |
Asymmetric dimethylarginine potentiates lung inflammation in a mouse model of allergic asthma.
Topics: Amidohydrolases; Animals; Arginine; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzyme Inhibitors; Epithelial Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide Synthase Type II; Nitrites; Ovalbumin; Pneumonia; Respiratory Mucosa | 2010 |
The impact of rapid atrial pacing on ADMA and endothelial NOS.
Topics: Aged; Animals; Arginine; Atrial Fibrillation; Calcium-Binding Proteins; Disease Models, Animal; Endothelium, Vascular; Female; Heart Rate; Human Umbilical Vein Endothelial Cells; Humans; Male; Middle Aged; Myocardial Contraction; Nitric Oxide Synthase Type III; Oxidative Stress; Pacemaker, Artificial; Risk Factors; Swine; Tachycardia; Ventricular Function, Left | 2012 |
Ramipril retards development of aortic valve stenosis in a rabbit model: mechanistic considerations.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve; Aortic Valve Stenosis; Arginine; Carrier Proteins; Disease Models, Animal; Disease Progression; Echocardiography; Enzyme Inhibitors; Ergocalciferols; Humans; Male; Rabbits; Ramipril; Vitamins | 2011 |
Changes in the contents of enzymatic immature, mature, and non-enzymatic senescent cross-links of collagen after once-weekly treatment with human parathyroid hormone (1-34) for 18 months contribute to improvement of bone strength in ovariectomized monkeys
Topics: Animals; Arginine; Bone Density; Bone Density Conservation Agents; Calcium; Collagen; Compressive Strength; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Glycation End Products, Advanced; Lumbar Vertebrae; Lysine; Macaca fascicularis; Osteoporosis; Ovariectomy; Phosphates; Teriparatide; X-Ray Microtomography | 2011 |
Effects of nitric oxide on the primary bladder afferent activities of the rat with and without intravesical acrolein treatment.
Topics: Acrolein; Administration, Intravesical; Afferent Pathways; Animals; Arginine; Cystitis; Disease Models, Animal; Enzyme Inhibitors; Female; Irritants; Nerve Fibers, Myelinated; Nerve Fibers, Unmyelinated; Neural Conduction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2011 |
L-Arginine-induced acute pancreatitis results in mild lung inflammation without altered respiratory mechanics.
Topics: Acute Disease; Acute Lung Injury; Amylases; Animals; Arginine; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Inflammation Mediators; Lung; Male; Pancreas; Pancreatitis; Peroxidase; Pneumonia; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Respiratory Mechanics; Time Factors | 2011 |
Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling?
Topics: Aerosols; Animals; Arginase; Arginine; Asthma; Blotting, Western; Coloring Agents; Disease Models, Animal; Goblet Cells; Hydroxyproline; Hyperplasia; Immunohistochemistry; Inflammation; Lung; Mice; Nitrates; Nitrites; Ovalbumin; Simvastatin; Transforming Growth Factor beta1 | 2010 |
Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension.
Topics: Animals; Arginine; Blood Pressure; Cardiomegaly; Disease Models, Animal; Hypertension, Renal; Kidney; Male; Nephrectomy; Nitrates; Nitric Oxide; Nitrogen; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary | 2011 |
Hyperuricemia attenuates aortic nitric oxide generation, through inhibition of arginine transport, in rats.
Topics: Allopurinol; Animals; Aorta; Arginine; Benzbromarone; Biological Transport; Blood Pressure; Cationic Amino Acid Transporter 1; Disease Models, Animal; Hyperuricemia; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxonic Acid; Phosphorylation; Protein Kinase C-alpha; Rats; Rats, Wistar; Tyrosine; Uric Acid; Uricosuric Agents | 2011 |
Time course of asymmetric dimethylarginine (ADMA) and oxidative stress in fructose-hypertensive rats: a model related to metabolic syndrome.
Topics: Animals; Aorta; Arginine; Blood Glucose; Blood Pressure; Body Weight; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fructose; Heart Rate; Hypertension; Male; Metabolic Syndrome; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents | 2011 |
Panhematin provides a therapeutic benefit in experimental pancreatitis.
Topics: Acute Disease; Animals; Arginine; Carbon Monoxide; Chemokine CXCL1; Cytokines; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Hemin; Inflammation Mediators; Liver; Mice; Mice, Inbred Strains; Mice, Transgenic; Pancreas; Pancreatitis; Spleen; Up-Regulation | 2011 |
Reg4 protects against acinar cell necrosis in experimental pancreatitis.
Topics: Animals; Arginine; bcl-X Protein; Cell Death; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; ErbB Receptors; Lectins, C-Type; Male; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Pancreas; Pancreatitis-Associated Proteins; Pancreatitis, Acute Necrotizing; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Up-Regulation | 2011 |
Anticonvulsant effect of celecoxib on pentylenetetrazole-induced convulsion: Modulation by NO pathway.
Topics: Animals; Anticonvulsants; Arginine; Celecoxib; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Epilepsy; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Pyrazoles; Statistics, Nonparametric; Sulfonamides | 2010 |
Salvianolic acid B and tanshinone IIA attenuate myocardial ischemia injury in mice by NO production through multiple pathways.
Topics: Abietanes; Amino Acid Transport Systems, Basic; AMP-Activated Protein Kinases; Analysis of Variance; Animals; Arginine; Benzofurans; Cardiovascular Agents; Cationic Amino Acid Transporter 1; Cells, Cultured; Chromones; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothelial Cells; Enzyme Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Myocardial Infarction; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Messenger; Signal Transduction; Time Factors; Vasodilation | 2011 |
Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Flow Velocity; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Insulin; Male; Microvessels; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar | 2011 |
Atorvastatin improved scopolamine-induced impairment in memory acquisition in mice: involvement of nitric oxide.
Topics: Animals; Arginine; Atorvastatin; Cholinergic Antagonists; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Heptanoic Acids; Learning Disabilities; Memory; Memory Disorders; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyrroles; Scopolamine | 2011 |
Attenuation of pain-related behavior evoked by injury through blockade of neuropeptide Y Y2 receptor.
Topics: Analysis of Variance; Animals; Arginine; Benzazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Motor Activity; Neuralgia; Neurons; Neuropeptide Y; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Rotarod Performance Test; Spinal Cord | 2011 |
Remifentanil preconditioning reduces hepatic ischemia-reperfusion injury in rats via inducible nitric oxide synthase expression.
Topics: Analgesics, Opioid; Animals; Arginine; Blotting, Western; Cell Survival; Cytokines; Disease Models, Animal; Ischemic Preconditioning; Lipid Peroxidation; Liver; Liver Diseases; Male; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Reperfusion Injury; Transaminases | 2011 |
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Apoptosis; Arginine; Citrulline; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Agents; HT29 Cells; Humans; Hydrolases; Mice; Mice, Inbred C57BL; Ornithine; Protein Processing, Post-Translational; Protein-Arginine Deiminases; Up-Regulation | 2011 |
Neuronal nitric oxide synthase is involved in the induction of nerve growth factor-induced neck muscle nociception.
Topics: Animals; Arginine; Brain Stem; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Neck Muscles; Nerve Growth Factor; Nitric Oxide Synthase Type I; Pain; Reflex; Tension-Type Headache | 2011 |
Tetrahydrobiopterin depletion and NOS2 uncoupling contribute to heart failure-induced alterations in atrial electrophysiology.
Topics: Action Potentials; Animals; Arginine; Atrial Fibrillation; Atrial Function, Left; Biopterins; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Female; Heart Atria; Heart Failure; Kinetics; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Patch-Clamp Techniques; Superoxides; Up-Regulation; Ventricular Function, Left | 2011 |
Long-term enteral arginine supplementation in rats with intestinal ischemia and reperfusion.
Topics: Administration, Oral; Amino Acids; Animals; Arginine; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Ileal Diseases; Ileum; Male; Rats; Reperfusion Injury; Time Factors | 2012 |
The levels of nitric oxide and asymmetric dimethylarginine in the rat endometriosis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Disease Models, Animal; Endometriosis; Female; Nitric Oxide; Peritoneal Diseases; Random Allocation; Rats; Rats, Sprague-Dawley | 2011 |
FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development.
Topics: Abnormalities, Multiple; Alleles; Amino Acid Sequence; Animals; Arginine; Cell Cycle Proteins; Disease Models, Animal; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Humans; Lung; Mice; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Point Mutation; Pulmonary Alveoli; Sequence Alignment; Transforming Growth Factor beta; Ubiquitin-Protein Ligases | 2011 |
Effects of L-arginine pretreatment on nitric oxide metabolism and hepatosplanchnic perfusion during porcine endotoxemia.
Topics: Acidosis; Animals; Arginine; Bacteria; Blood Pressure; Carbon Dioxide; Dietary Supplements; Disease Models, Animal; Endotoxemia; Female; Gastrointestinal Tract; Lipopolysaccharides; Liver; Mucous Membrane; Nitric Oxide; Portal Vein; Random Allocation; Splanchnic Circulation; Swine | 2011 |
Dietary arginine depletion reduces depressive-like responses in male, but not female, mice.
Topics: Aggression; Animals; Anxiety; Arginine; Body Weight; Corticosterone; Depression; Disease Models, Animal; Female; Food, Fortified; Immobility Response, Tonic; Male; Maze Learning; Mice; Pregnancy; Sex Characteristics | 2011 |
Left ventricular hypertrophy is associated with inflammation in sodium loaded subtotal nephrectomized rats.
Topics: Animals; Arginine; Creatinine; Disease Models, Animal; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Inflammation; Interleukin-6; Kidney Failure, Chronic; Male; Nephrectomy; Parathyroid Hormone; Phosphates; Rats; Rats, Wistar; Risk Factors; Sclerosis; Sodium Chloride | 2011 |
Advanced glycation end products in myocardial reperfusion injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Arginine; Cardiac Surgical Procedures; Disease Models, Animal; Fasting; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Neopterin; Rabbits; Stroke Volume; Thrombolytic Therapy; Time Factors; Treatment Outcome; Ventricular Dysfunction, Left; Ventricular Function, Left; Young Adult | 2012 |
Melatonin treatment following stroke induction modulates L-arginine metabolism.
Topics: Animals; Arginine; Blotting, Western; Cell Line, Tumor; Disease Models, Animal; Humans; Male; Melatonin; Middle Cerebral Artery; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Stroke | 2011 |
L-NAME and L-arginine differentially ameliorate cigarette smoke-induced emphysema in mice.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Male; Mice; Mice, Inbred C57BL; Neutrophils; NG-Nitroarginine Methyl Ester; Nicotiana; Nitric Oxide; Oxidants; Oxidative Stress; Pulmonary Emphysema; Smoke; Smoking | 2011 |
Progressive erosion of β-cell function precedes the onset of hyperglycemia in the NOD mouse model of type 1 diabetes.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Glucose; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred NOD; Prediabetic State | 2011 |
Antinociceptive effect of the essential oil of Zingiber zerumbet in mice: possible mechanisms.
Topics: Administration, Oral; Analgesics; Animals; Arginine; Behavior, Animal; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Injections, Intraperitoneal; KATP Channels; Male; Medicine, Traditional; Mice; Mice, Inbred ICR; Neural Pathways; Nitric Oxide; Oils, Volatile; Pain; Pain Measurement; Pain Threshold; Plant Oils; Plant Roots; Plants, Medicinal; Protein Kinase C; Signal Transduction; TRPV Cation Channels; Zingiber officinale | 2011 |
The acute effects of mirtazapine on pain related behavior in healthy animals.
Topics: Analysis of Variance; Animals; Antidepressive Agents, Tricyclic; Arginine; Behavior, Animal; Cyproheptadine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Hippocampus; In Vitro Techniques; Male; Mianserin; Mice; Mirtazapine; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Serotonin Antagonists | 2011 |
GPRC6A regulates prostate cancer progression.
Topics: Adenocarcinoma; Animals; Arginine; Calcium; Cell Line, Tumor; Cell Proliferation; Chemotaxis; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Disease Progression; Humans; In Vitro Techniques; Male; Mice; Mice, Knockout; Osteocalcin; Prostate; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, G-Protein-Coupled; RNA, Messenger; RNA, Small Interfering | 2012 |
Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models.
Topics: Animals; Antipsychotic Agents; Apomorphine; Arginine; Catalepsy; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flavonoids; Indazoles; Male; Mice; Motor Activity; Nitric Oxide; Phytotherapy; Plant Leaves; Plant Preparations; Protein Kinase C; Psychotic Disorders; Rats; Rats, Wistar; Stereotyped Behavior; Syzygium; Tamoxifen | 2011 |
Treatment of experimental cerebral vasospasm by protein transduction of heme oxygenase 1 (HO-1) conjugated to a residue of 11 arginines.
Topics: Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Heme Oxygenase-1; Male; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles; Vasospasm, Intracranial | 2011 |
Chronic renal failure alters endothelial function in cerebral circulation in mice.
Topics: Analysis of Variance; Animals; Apolipoproteins E; Arginine; Arterioles; Blotting, Western; Caveolin 1; Cerebrovascular Circulation; Cerebrovascular Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Inflammation Mediators; Kidney Failure, Chronic; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Pia Mater; PPAR gamma; rho-Associated Kinases; Vascular Cell Adhesion Molecule-1; Vasodilation; Vasodilator Agents | 2011 |
Potent amyloidogenicity and pathogenicity of Aβ43.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Arginine; Cell Line, Tumor; Cerebral Cortex; Cognition Disorders; Disease Models, Animal; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Humans; Immunoprecipitation; Isoleucine; L-Lactate Dehydrogenase; Male; Maze Learning; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Transgenic; Middle Aged; Mutation; Neuroblastoma; Neurons; Peptide Fragments; Presenilin-1 | 2011 |
Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice.
Topics: Acetylcholine; Animals; Antioxidants; Aorta; Arginine; Diabetes Mellitus; Disease Models, Animal; Endothelium, Vascular; Insulin Resistance; Liver; Male; Mice; Mice, Obese; Nitroprusside; Obesity; Phenylephrine; Silybin; Silymarin; Vasoconstrictor Agents; Vasodilator Agents | 2011 |
Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
Topics: Administration, Oral; Animals; Antidepressive Agents; Arginine; Behavior, Animal; Blotting, Western; Cell Survival; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Male; Medicine, Traditional; Mice; Motor Activity; Neuroprotective Agents; Neurotransmitter Agents; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Proto-Oncogene Proteins c-akt; Signal Transduction; Solvents; Time Factors; Verbenaceae; Water | 2011 |
Dendritic cells promote pancreatic viability in mice with acute pancreatitis.
Topics: Acute Disease; Animals; Arginine; Ceruletide; Dendritic Cells; Diphtheria Toxin; Disease Models, Animal; Early Growth Response Protein 1; Interleukin-6; Kaplan-Meier Estimate; Male; Mice; Mice, Inbred C57BL; Pancreas; Pancreatitis; Phenotype; Time Factors; Tissue Survival | 2011 |
Involvement of nitric oxide-cGMP pathway in the antidepressant-like effect of ascorbic acid in the tail suspension test.
Topics: Animals; Antidepressive Agents; Arginine; Ascorbic Acid; Cyclic GMP; Depression; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Exploratory Behavior; Female; Hindlimb Suspension; Indazoles; Mice; N-Methylaspartate; Nitric Oxide; Oxadiazoles; Piperazines; Purines; Quinoxalines; Signal Transduction; Sildenafil Citrate; Sulfones | 2011 |
Role of neuropeptide Y Y₁ and Y₂ receptors on behavioral despair in a rat model of depression with co-morbid anxiety.
Topics: Amygdala; Analysis of Variance; Animals; Anxiety; Arginine; Autoradiography; Benzazepines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Exploratory Behavior; Hippocampus; Interpersonal Relations; Male; Neuropeptide Y; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Swimming; Time Factors | 2012 |
Neuroprotection by neuropeptide Y in cell and animal models of Parkinson's disease.
Topics: Adrenergic Agents; Analysis of Variance; Animals; Animals, Newborn; Arginine; Autoradiography; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Enzyme Inhibitors; Female; Functional Laterality; Humans; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroblastoma; Neurodegenerative Diseases; Neuropeptide Y; Neuroprotective Agents; Nortropanes; Oligopeptides; Oxidopamine; Parkinson Disease; Protein Binding; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Substantia Nigra; Tyrosine 3-Monooxygenase | 2012 |
[Effect of vitamin C on the condition of NO-synthase system in experimental stomach ulcer].
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Disease Models, Animal; Gastric Mucosa; Lipid Peroxidation; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Stomach Ulcer; Superoxide Dismutase | 2011 |
Assessment of the protective effects of oral tocotrienols in arginine chronic-like pancreatitis.
Topics: Administration, Oral; Animals; Arginine; Disease Models, Animal; Disease Progression; Male; Pancreas; Pancreatitis, Chronic; Rats; Rats, Wistar; Tocotrienols; Treatment Outcome | 2011 |
Endotoxemia affects citrulline, arginine and glutamine bioavailability.
Topics: Animals; Area Under Curve; Arginine; Biological Availability; Citrulline; Disease Models, Animal; Endotoxemia; Glutamine; Lipopolysaccharides; Male; Random Allocation; Rats; Rats, Sprague-Dawley | 2012 |
Scopolamine impairs behavioural function and arginine metabolism in the rat dentate gyrus.
Topics: Amino Acids; Animals; Arginine; Behavioral Symptoms; Body Weight; Brain Chemistry; Cholinergic Antagonists; Dentate Gyrus; Disease Models, Animal; Exploratory Behavior; gamma-Aminobutyric Acid; Male; Maze Learning; Nitric Oxide Synthase; Polyamines; Rats; Rats, Sprague-Dawley; Scopolamine | 2011 |
Systemic L-citrulline prevents cerebral vasospasm in haptoglobin 2-2 transgenic mice after subarachnoid hemorrhage.
Topics: Animals; Arginine; Basilar Artery; Cerebrovascular Circulation; Citrulline; Disease Models, Animal; Dose-Response Relationship, Drug; Genotype; Haptoglobins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2012 |
Notch3 Arg170Cys knock-in mice display pathologic and clinical features of the neurovascular disorder cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.
Topics: Animals; Arginine; Brain; CADASIL; Capillaries; Cystine; Disease Models, Animal; Fertility; Gene Knock-In Techniques; Mice; Motor Activity; Muscle, Smooth, Vascular; Mutation; Receptor, Notch3; Receptors, Notch | 2011 |
Effect of nitric oxide in protective effect of melatonin against chronic constriction sciatic nerve injury induced neuropathic pain in rats.
Topics: Animals; Antioxidants; Arginine; Catalase; Chronic Disease; Disease Models, Animal; Glutathione; Hyperalgesia; Lipid Peroxidation; Male; Melatonin; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve | 2011 |
Effect of Lactobacillus plantarum and L-arginine against endotoxin-induced liver injury in a rat model.
Topics: Alanine Transaminase; Animals; Arginine; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Kupffer Cells; Lactobacillus plantarum; Lipopolysaccharides; Liver; Nitric Oxide; Probiotics; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2011 |
The neuropeptide Y (NPY)-ergic system is associated with behavioral resilience to stress exposure in an animal model of post-traumatic stress disorder.
Topics: Animals; Arginine; Brain; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Down-Regulation; Gene Expression Regulation; Humans; Male; Maze Learning; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Reflex, Startle; Resilience, Psychological; Stress Disorders, Post-Traumatic; Stress, Psychological | 2012 |
Multidrug strategies are effective in the treatment of severe experimental pancreatitis.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Dextrans; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats | 2012 |
A dietary approach to increase in-stent stenosis and face validity of a rat model for arterial angioplasty and stenting.
Topics: Angioplasty, Balloon; Animals; Arginine; Biomarkers; Carotid Arteries; Carotid Artery Injuries; Carotid Stenosis; Choline Deficiency; Diet, Atherogenic; Disease Models, Animal; Endothelial Cells; Female; Hyperplasia; Inflammation Mediators; Interleukin-6; Lipids; Male; Platelet Activation; Rats; Rats, Sprague-Dawley; Recurrence; Reproducibility of Results; Stents; Thromboxane B2; Time Factors; Ultrasonography, Doppler, Color | 2011 |
Citrulline: a potential immunomodulator in sepsis.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Endothelial Cells; Immunologic Factors; Inflammation Mediators; Interleukin-10; Interleukin-6; Interleukin-8; Nitric Oxide; Rats; Rats, Wistar; Sepsis | 2011 |
Arginyl-glutamine dipeptide or docosahexaenoic acid attenuates hyperoxia-induced small intestinal injury in neonatal mice.
Topics: Animals; Animals, Newborn; Apoptosis; Arginine; Dietary Supplements; Dipeptides; Disease Models, Animal; Docosahexaenoic Acids; Female; Glutamine; Hyperoxia; Intestinal Mucosa; Intestine, Small; L-Lactate Dehydrogenase; Mice; Mice, Inbred C57BL; Peroxidase | 2012 |
Comparison of the antinociceptive effects of ibuprofen arginate and ibuprofen in rat models of inflammatory and neuropathic pain.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Cold Temperature; Disease Models, Animal; Drug Combinations; Ibuprofen; Inflammation; Male; Neuralgia; Physical Stimulation; Rats; Rats, Sprague-Dawley; Sciatic Neuropathy | 2012 |
Establishment and characterization of a murine model for allergic asthma using allergen-specific IgE monoclonal antibody to study pathological roles of IgE.
Topics: Allergens; Animals; Antigen-Antibody Complex; Arginine; Asthma; Benzhydryl Compounds; Bronchial Hyperreactivity; Cell Movement; Chronic Disease; Disease Models, Animal; Goblet Cells; Humans; Hyperplasia; Immunization; Immunoglobulin E; Immunoglobulin G; Mice; Mice, Inbred BALB C; Neutrophils; Ovalbumin; Receptors, Complement | 2012 |
Requirement of argininosuccinate lyase for systemic nitric oxide production.
Topics: Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Argininosuccinic Aciduria; Cell Line; Disease Models, Animal; Endothelial Cells; Female; Fibroblasts; Gene Knockdown Techniques; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitrites; RNA, Small Interfering; Sequence Analysis, DNA; Swine | 2011 |
Arginine-engrafted biodegradable polymer for the systemic delivery of therapeutic siRNA.
Topics: Animals; Arginine; Biocompatible Materials; Cell Line, Tumor; Cell Proliferation; Chemical Phenomena; Disease Models, Animal; Gene Knockdown Techniques; Gene Silencing; Gene Transfer Techniques; Melanoma; Mice; Polymers; RNA, Small Interfering | 2012 |
Crystal structure of an arthritogenic anticollagen immune complex.
Topics: Amino Acid Motifs; Animals; Antibody Specificity; Antigen-Antibody Complex; Arginine; Arthritis; Autoantibodies; B-Lymphocytes; Cell Line; Collagen Type II; Crystallization; Disease Models, Animal; Humans; Mice; Protein Conformation | 2011 |
Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential.
Topics: Agammaglobulinemia; Amino Acid Substitution; Animals; Antibodies, Monoclonal; Arginine; Binding, Competitive; Cell Line, Tumor; Disease Models, Animal; Half-Life; Histidine; Histocompatibility Antigens Class I; Humans; Hydrogen-Ion Concentration; Immunoglobulin G; Mice; Molecular Targeted Therapy; Pneumococcal Infections; Protein Binding; Protein Transport; Receptors, Fc; Streptococcus pneumoniae | 2011 |
Involvement of the L-arginine-nitric oxide pathway in the antinociception caused by fruits of Prosopis strombulifera (Lam.) Benth.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Argentina; Arginine; Aspirin; Cell Line; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Fruit; Macrophages; Male; Medicine, Traditional; Mice; Mice, Inbred Strains; Morphine; Nitric Oxide; Nitric Oxide Synthase Type II; Pain; Phytotherapy; Plant Extracts; Prosopis | 2012 |
[Pharmacological modulation of nitrogen oxide system in experimental chronic alcoholic intoxication in rats].
Topics: Alcoholism; Amino Acids; Animals; Animals, Outbred Strains; Arginine; Catalase; Complex Mixtures; Disease Models, Animal; Drug Administration Schedule; Intercellular Signaling Peptides and Proteins; Male; Neuropeptides; Neuroprotective Agents; Neurotoxicity Syndromes; Nitric Oxide; Nitric Oxide Synthase; Peptides; Rats; Superoxide Dismutase | 2011 |
CCL2-induced migration and SOCS3-mediated activation of macrophages are involved in cerulein-induced pancreatitis in mice.
Topics: Acute Disease; Animals; Arginine; Biomarkers; CD11b Antigen; CD11c Antigen; Ceruletide; Chemokine CCL2; Chemotaxis; Disease Models, Animal; DNA-Binding Proteins; Enzymes; Immunity, Innate; Lymphocyte Depletion; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreas; Pancreatitis; Parabiosis; Receptors, CCR2; Receptors, Chemokine; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins | 2012 |
Role of neuronal nitric oxide synthase in the antiallodynic effects of intrathecal EGCG in a neuropathic pain rat model.
Topics: Animals; Arginine; Catechin; Disease Models, Animal; Extremities; Hyperalgesia; Injections, Spinal; Ligation; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves | 2012 |
Nicotine evoked improvement in learning and memory is mediated through NPY Y1 receptors in rat model of Alzheimer's disease.
Topics: Alzheimer Disease; Amygdala; Analysis of Variance; Animals; Arcuate Nucleus of Hypothalamus; Arginine; Colchicine; Dentate Gyrus; Disease Models, Animal; Escape Reaction; Learning; Male; Maze Learning; Memory; Neuropeptide Y; Nicotine; Nicotinic Agonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Septal Nuclei | 2012 |
Inhibition of eNOS phosphorylation mediates endothelial dysfunction in renal failure: new effect of asymmetric dimethylarginine.
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide Synthase Type III; Phosphorylation; Recombinant Proteins; Renal Insufficiency, Chronic; Vasodilation | 2012 |
Opposite caudal versus rostral brain nitric oxide synthase response to generalized seizures in a novel rodent model of reflex epilepsy.
Topics: Animals; Arginine; Brain; Cricetinae; Disease Models, Animal; Epilepsy, Reflex; Isoenzymes; Nitric Oxide; Nitric Oxide Synthase; Seizures | 2012 |
Elevation of cartilage AGEs does not accelerate initiation of canine experimental osteoarthritis upon mild surgical damage.
Topics: Animals; Arginine; Cartilage, Articular; Chondrocytes; Disease Models, Animal; Dogs; Female; Glycation End Products, Advanced; Lysine; Osteoarthritis; Synovitis | 2012 |
Involvement of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in peripheral antinociception induced by N-palmitoyl-ethanolamine in rats.
Topics: Amides; Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Endocannabinoids; Ethanolamines; Hyperalgesia; Male; Neural Inhibition; Neural Pathways; Nitric Oxide; Nociception; Palmitic Acids; Rats; Rats, Wistar | 2012 |
Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure.
Topics: Animals; Arginase; Arginine; Citrulline; Disease Models, Animal; Female; Liver; Liver Failure, Acute; Nitric Oxide; Ornithine; Portacaval Shunt, Surgical; Sus scrofa | 2012 |
Effect of chronic L-Arginine supplementation on aortic fatty streak formation and serum nitric oxide concentration in normal and high-cholesterol fed rabbits.
Topics: Animals; Aortic Diseases; Arginine; Cholesterol, Dietary; Disease Models, Animal; Hypercholesterolemia; Lipids; Male; Nitric Oxide; Plaque, Atherosclerotic; Rabbits | 2012 |
L-citrulline prevents alveolar and vascular derangement in a rat model of moderate hyperoxia-induced lung injury.
Topics: Animals; Animals, Newborn; Arginine; Citrulline; Disease Models, Animal; Endothelium, Vascular; Female; Hyperoxia; Lung; Lung Injury; Matrix Metalloproteinase 2; Nitric Oxide; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Vascular Endothelial Growth Factor A | 2012 |
The effects of hypothermia and L-arginine on skeletal muscle function in ischemia-reperfusion injury.
Topics: Animals; Arginine; Disease Models, Animal; Hyperthermia, Induced; Hypothermia, Induced; Male; Muscle Contraction; Muscle, Skeletal; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion; Reperfusion Injury | 2012 |
Nitric oxide synthase, ADMA, SDMA, and nitric oxide activity in the paraventricular nucleus throughout the etiology of renal wrap hypertension.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Hypertension, Renal; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley | 2012 |
Metabolomic analysis to discover candidate therapeutic agents against acute pancreatitis.
Topics: Acute Disease; Amino Acids; Animals; Arginine; Ceruletide; Citric Acid Cycle; Disease Models, Animal; Ethanolamines; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Male; Metabolomics; Mice; Mice, Inbred C57BL; Pancreatitis | 2012 |
Chemokine receptor CXCR3 is involved in the acute pancreatitis-associated lung injury.
Topics: Acute Disease; Acute Lung Injury; Amylases; Animals; Arginine; Ceruletide; Disease Models, Animal; Lipase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreatitis; Receptors, CXCR3; Severity of Illness Index | 2012 |
Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis.
Topics: Acute Disease; Animals; Arginase; Arginine; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Male; Methylation; Multiple Sclerosis; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2012 |
Protective effect of ω-3 polyunsaturated fatty acids on L-arginine-induced nephrotoxicity and oxidative damage in rat kidney.
Topics: Animals; Antioxidants; Arginine; Biomarkers; Blood Urea Nitrogen; Carbohydrate Metabolism; Creatinine; Cytoprotection; Dietary Supplements; Disease Models, Animal; Enzymes; Fatty Acids, Omega-3; Fish Oils; Kidney; Kidney Diseases; Linseed Oil; Lipid Peroxidation; Lysosomes; Male; Microvilli; Oxidative Stress; Phosphates; Rats; Rats, Wistar | 2012 |
Nitric-oxide supplementation for treatment of long-term complications in argininosuccinic aciduria.
Topics: Adolescent; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinic Aciduria; Child, Preschool; Chromatography, High Pressure Liquid; Disease Models, Animal; Genetic Therapy; Humans; Hypertension; Liver; Male; Mice; Nitric Oxide | 2012 |
Discovery of novel indane derivatives as liver-selective thyroid hormone receptor β (TRβ) agonists for the treatment of dyslipidemia.
Topics: Animals; Arginine; Cholesterol; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Dyslipidemias; Humans; Indans; Ligands; Liver; Male; Malonates; Models, Molecular; Molecular Mimicry; Molecular Structure; Rats; Rats, Wistar; Small Molecule Libraries; Structure-Activity Relationship; Thyroid Hormone Receptors beta | 2012 |
Effects of nitric oxide on renal interstitial fibrosis in rats with unilateral ureteral obstruction.
Topics: Animals; Arginine; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Hypoxia-Inducible Factor 1, alpha Subunit; Kidney; Male; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Ureteral Obstruction; Vascular Endothelial Growth Factor A | 2012 |
Preserving mitochondrial function prevents the proteasomal degradation of GTP cyclohydrolase I.
Topics: Acetylcarnitine; Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; Arginine; Biopterins; Disease Models, Animal; Endothelial Cells; Female; GTP Cyclohydrolase; HSP70 Heat-Shock Proteins; Hypertension, Pulmonary; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pulmonary Artery; Pulmonary Heart Disease; Sheep; Signal Transduction; Ubiquitin-Protein Ligases; Ubiquitination | 2012 |
An affective disorder in zebrafish with mutation of the glucocorticoid receptor.
Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Anti-Anxiety Agents; Arginine; Brain; Cell Line, Transformed; Chlorocebus aethiops; Corticotropin-Releasing Hormone; Cysteine; Diazepam; Disease Models, Animal; Escape Reaction; Exploratory Behavior; Fluoxetine; Freezing Reaction, Cataleptic; Hormone Antagonists; Humans; Hydrocortisone; Interpersonal Relations; Mifepristone; Mood Disorders; Mutation; Psychomotor Agitation; Radioimmunoassay; Receptors, Glucocorticoid; Serotonin; Transfection; Zebrafish | 2013 |
Thrombin activity associated with neuronal damage during acute focal ischemia.
Topics: Amino Acids; Analysis of Variance; Animals; Antithrombins; Arginine; Avoidance Learning; Brain Injuries; Cell Death; Cognition Disorders; Disease Models, Animal; Factor X; Fibrinolysin; Gene Expression Regulation; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Maze Learning; Motor Activity; Nerve Tissue Proteins; Pipecolic Acids; Pyrroles; Rats; Reaction Time; Receptor, PAR-1; Sulfonamides; Thrombin; Time Factors | 2012 |
Changes in optic nerve head circulation in response to vasoactive agents: intereye comparison in monkeys with experimental unilateral glaucoma.
Topics: Animals; Arginine; Blood Circulation; Blood Flow Velocity; Calcium Channel Blockers; Disease Models, Animal; Enzyme Inhibitors; Female; Glaucoma; Intraocular Pressure; Lasers, Gas; Macaca fascicularis; NG-Nitroarginine Methyl Ester; Nifedipine; Optic Disk; Piperazines; Regional Blood Flow; Tonometry, Ocular; Trabecular Meshwork | 2012 |
Beneficial effects of the active principle component of Korean cabbage kimchi via increasing nitric oxide production and suppressing inflammation in the aorta of apoE knockout mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Aortitis; Apolipoproteins E; Arginine; Atherosclerosis; Biopterins; Cell Adhesion Molecules; Diet, Atherogenic; Disease Models, Animal; Down-Regulation; Injections, Intraperitoneal; Male; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Phenyl Ethers; Propionates; Random Allocation; Reactive Oxygen Species; Up-Regulation | 2013 |
Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Guanosine; Hindlimb Suspension; Immunosuppressive Agents; Male; Mice; N-Methylaspartate; Nitric Oxide; Phosphatidylinositol 3-Kinases; Receptors, N-Methyl-D-Aspartate; Serine; Signal Transduction; Sirolimus; Swimming; TOR Serine-Threonine Kinases | 2012 |
Proteinuria elevates asymmetric dimethylarginine levels via protein arginine methyltransferase-1 overexpression in a rat model of nephrotic syndrome.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Cells, Cultured; Disease Models, Animal; Doxorubicin; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Kidney Tubules, Proximal; Male; Nephrotic Syndrome; Oxidative Stress; Protein-Arginine N-Methyltransferases; Proteinuria; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Serum Albumin; Time Factors | 2012 |
Protective effect of nitric oxide on hepatopulmonary syndrome from ischemia-reperfusion injury.
Topics: Alanine Transaminase; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Hepatorenal Syndrome; Immunohistochemistry; Intercellular Adhesion Molecule-1; Liver; Liver Transplantation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha | 2012 |
Hsp72 overexpression accelerates the recovery from caerulein-induced pancreatitis.
Topics: Acute Disease; Animals; Arginine; Ceruletide; Disease Models, Animal; Gene Expression; Gene Expression Regulation; HSP72 Heat-Shock Proteins; Mice; Mice, Transgenic; NF-kappa B; Pancreas, Exocrine; Pancreatitis; Recovery of Function; Signal Transduction | 2012 |
Beneficial effects of Nrf2 overexpression in a mouse model of Alexander disease.
Topics: Age Factors; Alexander Disease; Alkaline Phosphatase; Animals; Arginine; Astrocytes; Body Weight; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamate-Cysteine Ligase; Glutathione; GPI-Linked Proteins; Histidine; Humans; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Fibers; NF-E2-Related Factor 2; RNA, Messenger | 2012 |
The Fgfr2 W290R mouse model of Crouzon syndrome.
Topics: Animals; Arginine; Bone and Bones; Cartilage; Cranial Sutures; Craniofacial Dysostosis; Disease Models, Animal; Humans; Mice; Mutation; Phenotype; Receptor, Fibroblast Growth Factor, Type 2; Tryptophan | 2012 |
Post-translational oxidative modification and inactivation of mitochondrial complex I in epileptogenesis.
Topics: Analysis of Variance; Animals; Arginine; Biotinylation; Brain; Disease Models, Animal; Electron Transport Complex I; Electron Transport Complex IV; Excitatory Amino Acid Agonists; Kainic Acid; Male; Mitochondria; Models, Molecular; Molecular Weight; Oxidative Stress; Peptide Mapping; Protein Carbonylation; Protein Processing, Post-Translational; Protein Subunits; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Status Epilepticus; Synaptosomes; Time Factors | 2012 |
Anti-inflammatory effect of arginase inhibitor and corticosteroid on airway allergic reactions in a Dermatophogoides farinae-induced NC/Nga mouse model.
Topics: Animals; Arginase; Arginine; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Dermatophagoides farinae; Disease Models, Animal; Interleukin-13; Interleukin-4; Interleukin-5; Lung; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Prednisolone; RNA, Messenger | 2013 |
N (w) -propyl-L-arginine (L-NPA) reduces status epilepticus and early epileptogenic events in a mouse model of epilepsy: behavioural, EEG and immunohistochemical analyses.
Topics: Animals; Arginine; Brain Waves; Dentate Gyrus; Diazepam; Disease Models, Animal; Gliosis; Immunohistochemistry; Kainic Acid; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Seizures; Status Epilepticus; Synapses; Synaptophysin; Telemetry | 2012 |
Lesson from acute experimental pancreatitis: multidrug strategies is effective than single-target therapy.
Topics: Acetylcysteine; Animals; Antibodies, Monoclonal; Arginine; Disease Models, Animal; Drug Therapy, Combination; Free Radical Scavengers; Gabexate; Humans; Intercellular Adhesion Molecule-1; Male; Microcirculation; Nitric Oxide Donors; Pancreas; Pancreatitis, Acute Necrotizing; Platelet Activating Factor; Protease Inhibitors; Rats; Survival Analysis; Survival Rate; Treatment Outcome | 2012 |
Assessment of the endothelial functions in monocrotaline-induced pulmonary hypertension.
Topics: Animals; Aorta, Thoracic; Arginine; Disease Models, Animal; Endothelium, Vascular; Hydrogen Sulfide; Hypertension, Pulmonary; Iloprost; Male; Monocrotaline; Nitric Oxide; Piperazines; Pulmonary Artery; Purines; Rats; Rats, Sprague-Dawley; Sildenafil Citrate; Sulfones; Vasodilation; Vasodilator Agents | 2013 |
Developmental programming of eNOS uncoupling and enhanced vascular oxidative stress in adult rats after transient neonatal oxygen exposure.
Topics: Age Factors; Animals; Animals, Newborn; Aorta; Arginine; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Hyperoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Pterins; Rats; Rats, Sprague-Dawley; Superoxides; Vasodilation; Vasodilator Agents | 2013 |
Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure.
Topics: Adult; Animals; Arginine; Blood Pressure; Disease Models, Animal; Female; Humans; Hypertension; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Mitochondria; Nitric Oxide; Transaminases | 2012 |
Study of L-arginine in intestinal lesions caused by ischemia-reperfusion in rats.
Topics: Animals; Arginine; Cytoprotection; Disease Models, Animal; Electric Stimulation; Enteric Nervous System; Gastrointestinal Agents; Gastrointestinal Motility; Jejunum; Male; Potassium Chloride; Rats; Rats, Wistar; Reperfusion Injury | 2012 |
Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.
Topics: Acinar Cells; Amylases; Animals; Arginine; Cytokines; Disease Models, Animal; Gene Expression; Inflammation; Injections, Intraperitoneal; Injections, Intravenous; Islets of Langerhans; Lung; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factors; Netrin-1; NF-kappa B; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Tumor Suppressor Proteins | 2012 |
Involvement of neuropeptide Y signaling in the antidepressant-like effect and hippocampal cell proliferation induced by kososan, a Kampo medicine, in the stress-induced depression-like model mice.
Topics: Animals; Antidepressive Agents; Arginine; Cell Proliferation; Depression; Disease Models, Animal; Drugs, Chinese Herbal; Hippocampus; Intracellular Signaling Peptides and Proteins; Male; Medicine, Kampo; Mice; Neuropeptide Y; Neuropeptides; Orexins; Signal Transduction; Stress, Psychological | 2012 |
Deletion of IκBα activates RelA to reduce acute pancreatitis in mice through up-regulation of Spi2A.
Topics: Acinar Cells; alpha 1-Antichymotrypsin; Animals; Arginine; Ceruletide; Cytosol; Disease Models, Animal; Gene Expression Profiling; Genetic Vectors; Genotype; I-kappa B Proteins; Lentivirus; Mice; Mice, Inbred C57BL; Microarray Analysis; NF-kappa B; NF-KappaB Inhibitor alpha; Nuclear Proteins; Pancreas; Pancreatitis; Phosphorylation; Serpins; Signal Transduction; Transcription Factor RelA; Trypsin; Up-Regulation | 2013 |
S-nitrosylated protein disulfide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Biotin; Cell Line, Tumor; Cysteine; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mice, Transgenic; Mutation; Neuroblastoma; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Disulfide-Isomerases; Protein Folding; S-Nitrosothiols; Spinal Cord; Subcellular Fractions; Superoxide Dismutase; Up-Regulation | 2013 |
Treatment with heme arginate alleviates adipose tissue inflammation and improves insulin sensitivity and glucose metabolism in a rat model of Human primary aldosteronism.
Topics: Adiposity; Animals; Arginine; Chemokine CCL2; Disease Models, Animal; Endothelin-1; Enzyme Activators; Gene Expression; Glucose; Heme; Heme Oxygenase (Decyclizing); Humans; Hyperaldosteronism; Insulin; Insulin Resistance; Intercellular Adhesion Molecule-1; Intra-Abdominal Fat; JNK Mitogen-Activated Protein Kinases; Male; Mesoporphyrins; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor AP-1 | 2012 |
Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous L-arginine.
Topics: Animals; Arginine; Blood Pressure; Chronic Disease; Citrulline; Compliance; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Lung; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Perfusion; Pulmonary Artery; Pulmonary Veins; Rats; Rats, Sprague-Dawley; Time Factors; Vascular Resistance; Vasoconstriction; Ventricular Dysfunction, Right | 2013 |
Comparing beneficial effects of inhaled nitric oxide to L-arginine in necrotizing enterocolitis model in neonatal rats.
Topics: Administration, Inhalation; Animals; Animals, Newborn; Arginine; Disease Models, Animal; Enterocolitis, Necrotizing; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2012 |
Antisickling fetal hemoglobin reduces hypoxia-inducible factor-1α expression in normoxic sickle mice: microvascular implications.
Topics: alpha-Globins; Anemia, Sickle Cell; Animals; Arginine; Arterioles; beta-Globins; Blood Pressure; Disease Models, Animal; Down-Regulation; Endothelin-1; Fetal Hemoglobin; Heme Oxygenase-1; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microcirculation; Nitric Oxide; Regional Blood Flow; Vascular Endothelial Growth Factor A; Vasodilation | 2013 |
Effect of acute pancreatitis on the pharmacokinetics of Chinese herbal ointment Liu-He-Dan in anaesthetized rats.
Topics: Administration, Cutaneous; Amylases; Animals; Anthraquinones; Arginine; Disease Models, Animal; Drugs, Chinese Herbal; Emodin; Male; Ointments; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley | 2013 |
Antinociceptive activity of carvacrol (5-isopropyl-2-methylphenol) in mice.
Topics: Abdominal Pain; Acetic Acid; Analgesics; Animals; Arginine; Behavior, Animal; Cymenes; Disease Models, Animal; Formaldehyde; Hot Temperature; Male; Mice; Mice, Inbred Strains; Monoterpenes; Motor Activity; Naloxone; Narcotic Antagonists; Oils, Volatile; Origanum; Pain; Phytotherapy; Plant Extracts; Thymus Plant | 2012 |
Dietary supplementation of some antioxidants against hypoxia.
Topics: Animals; Antioxidants; Arginine; Chemical and Drug Induced Liver Injury; Cytoprotection; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Energy Metabolism; Hypoxia; Liver; Male; Melatonin; Oxidative Stress; Rats; Reactive Oxygen Species; Sodium Nitrite; Time Factors; Ubiquinone | 2012 |
Disruption of endothelial cell mitochondrial bioenergetics in lambs with increased pulmonary blood flow.
Topics: Adenosine Triphosphate; Animals; Arginine; Carnitine; Disease Models, Animal; Endothelial Cells; Heart Defects, Congenital; Homeostasis; Hypertension, Pulmonary; Lung; Mitochondria; Nitric Oxide; Nitric Oxide Synthase Type III; Pulmonary Circulation; Regional Blood Flow; Sheep; Signal Transduction | 2013 |
Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice.
Topics: Action Potentials; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Cell Differentiation; Cells, Cultured; Charcot-Marie-Tooth Disease; Chlorocebus aethiops; COS Cells; Curcumin; Cysteine; Disease Models, Animal; DNA-Binding Proteins; Early Growth Response Protein 2; Electric Stimulation; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Mice; Mice, Transgenic; Motor Activity; Muscle Strength; Mutation; Myelin P0 Protein; Neuromuscular Junction; Octamer Transcription Factor-6; Protein Folding; Proto-Oncogene Proteins c-jun; Regulatory Factor X Transcription Factors; Rotarod Performance Test; Schwann Cells; Transcription Factors; Transfection; X-Box Binding Protein 1 | 2012 |
Antinociceptive effect of Lecythis pisonis Camb. (Lecythidaceae) in models of acute pain in mice.
Topics: Acetic Acid; Acute Pain; Analgesics; Animals; Arginine; Behavior, Animal; Capsaicin; Disease Models, Animal; Formaldehyde; Glutamic Acid; Glyburide; Lecythidaceae; Male; Mice; Naloxone; Narcotic Antagonists; Phytotherapy; Plant Extracts; Plant Leaves | 2013 |
Melatonin regulates L-arginine transport and NADPH oxidase in young rats with bile duct ligation: role of protein kinase C.
Topics: Animals; Arginase; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cholestasis, Extrahepatic; Common Bile Duct; Disease Models, Animal; Female; Injections, Intraperitoneal; Kidney; Ligation; Liver; Male; Melatonin; NADPH Oxidases; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Transport; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2013 |
Basal release of nitric oxide in the mesenteric artery in portal hypertension and cirrhosis: role of dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Endothelium, Vascular; Hypertension, Portal; In Vitro Techniques; Liver Cirrhosis, Experimental; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Vasodilation | 2013 |
Involvement of the nitric oxide/cyclic guanylate monophosphate pathway in the pilocarpine-induced seizure model in mice.
Topics: Amidines; Animals; Arginine; Benzylamines; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Guanidines; Guanylate Cyclase; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pilocarpine; Receptors, Cytoplasmic and Nuclear; Seizures; Soluble Guanylyl Cyclase | 2013 |
L-arginine or tempol supplementation improves renal and cardiovascular function in rats with reduced renal mass and chronic high salt intake.
Topics: Animals; Antioxidants; Arginine; Blood Pressure; Cardiovascular System; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Kidney; Male; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride, Dietary; Spin Labels | 2013 |
The effects of topical L-arginine and Ng-nitro-L-arginine methyl ester after experimental acute spinal cord injury. A light and electron microscopic study.
Topics: Administration, Topical; Animals; Arginine; Blood Flow Velocity; Disease Models, Animal; Enzyme Inhibitors; Male; Microscopy; Microscopy, Electron; NG-Nitroarginine Methyl Ester; Rabbits; Regional Blood Flow; Spinal Cord; Spinal Cord Injuries; Spinal Cord Ischemia | 2002 |
Effect of deferoxamine and L-arginine treatment on lipid peroxidation in an intestinal ischaemia-reperfusion model in rats.
Topics: Animals; Arginine; Deferoxamine; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Female; Glutathione Peroxidase; Ischemia; Jejunum; Lipid Peroxidation; Malondialdehyde; Nitric Oxide; Rats; Rats, Wistar; Reperfusion; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2002 |
Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1.
Topics: Animals; Arginine; Cytosine; Disease Models, Animal; Flow Cytometry; Genes, Dominant; Genome; Growth; Humans; Mice; Point Mutation; Thyroid Hormone Receptors alpha | 2002 |
Effects of supplemental L-arginine on the intestinal adaptive response after massive small-bowel resection in rats.
Topics: Adaptation, Physiological; Animals; Arginine; Disease Models, Animal; Intestine, Small; Male; Postoperative Period; Random Allocation; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome | 2002 |
Oral L-arginine prevents murine coxsackievirus B3 myocarditis.
Topics: Administration, Oral; Animals; Arginine; Coxsackievirus Infections; Disease Models, Animal; Enterovirus B, Human; Enzyme Inhibitors; Male; Mice; Mice, Inbred C3H; Myocarditis; NG-Nitroarginine Methyl Ester; Severity of Illness Index; Survival Rate | 2002 |
Selective mediation of nerve injury-induced tactile hypersensitivity by neuropeptide Y.
Topics: Animals; Arginine; Benzazepines; Disease Models, Animal; Disease Progression; Ganglia, Spinal; Hyperalgesia; Immune Sera; Ligation; Lumbosacral Region; Male; Medulla Oblongata; Microinjections; Nerve Crush; Neuropeptide Y; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Rhizotomy; Spinal Cord; Spinal Nerves | 2002 |
Nitric oxide synthase inhibitors affect nitric oxide synthesis in normoxic but not in ischemic organs during intestinal ischemia and early reperfusion.
Topics: Animals; Arginine; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Intestines; Liver; Lung; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
L-arginine impacts pulmonary vascular structure in rats with an aortocaval shunt.
Topics: Animals; Aorta; Apoptosis; Arginine; Arteriovenous Shunt, Surgical; Cell Division; Disease Models, Animal; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Male; Muscle, Smooth, Vascular; Pulmonary Artery; Pulmonary Circulation; Pulmonary Wedge Pressure; Rats; Rats, Sprague-Dawley; Vena Cava, Inferior | 2002 |
Esophageal dysmotility and the change of synthesis of nitric oxide in a feline esophagitis model.
Topics: Animals; Arginine; Cyclic GMP; Disease Models, Animal; Esophageal Motility Disorders; Esophagitis; Male; Nitric Oxide; Nitric Oxide Synthase; Probability; Random Allocation; Reference Values; Sensitivity and Specificity | 2002 |
Delayed argatroban treatment reduces edema in a rat model of intracerebral hemorrhage.
Topics: Animals; Antithrombins; Arginine; Brain; Brain Chemistry; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Hemoglobins; Infusions, Parenteral; Male; Microinjections; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Sulfonamides; Time Factors; Treatment Outcome; Water | 2002 |
Coinduction of nitric oxide synthase and arginine metabolic enzymes in endotoxin-induced uveitis rats.
Topics: Animals; Arginase; Arginine; Argininosuccinate Synthase; Disease Models, Animal; Enzyme Induction; Lipopolysaccharides; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Uveitis | 2002 |
Thrombosis increases circulatory hepatocyte growth factor by degranulation of mast cells.
Topics: Animals; Anticoagulants; Arginine; Carotid Artery Thrombosis; Cell Degranulation; Disease Models, Animal; Disease Progression; Hepatocyte Growth Factor; Histamine; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Pipecolic Acids; Proto-Oncogene Proteins c-kit; Rats; Rats, Inbred Strains; Rats, Wistar; Reperfusion; Sulfonamides; Thrombin | 2002 |
Differential regulation of glomerular arginine transporters (CAT-1 and CAT-2) in lipopolysaccharide-treated rats.
Topics: Animals; Arginine; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glomerular Mesangium; In Vitro Techniques; Ion Transport; Kidney Glomerulus; Lipopolysaccharides; Lysine; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; RNA, Messenger; Sepsis; Sodium | 2003 |
Arginase inhibition slows the progression of renal failure in rats with renal ablation.
Topics: Animals; Arginase; Arginine; Body Weight; Disease Models, Animal; Disease Progression; Enzyme Activation; Food, Formulated; Hemodynamics; Kidney; Kidney Failure, Chronic; Liver; Male; Manganese; Rats; Rats, Sprague-Dawley | 2003 |
Effects of chronic treatment with L-arginine on atherosclerosis in apoE knockout and apoE/inducible NO synthase double-knockout mice.
Topics: Animals; Aorta; Apolipoproteins E; Arginine; Arteriosclerosis; Biopterins; Blotting, Western; Cholesterol; Disease Models, Animal; Immunohistochemistry; Isoenzymes; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Staining and Labeling; Thiobarbituric Acid Reactive Substances; Tyrosine | 2003 |
Of mice and men (and rats): implications of species and stimulus differences for the interpretation of studies of nitric oxide in sepsis.
Topics: Animals; Arginine; Cells, Cultured; Cytokines; Disease Models, Animal; Dogs; Heme Oxygenase (Decyclizing); Humans; Mice; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Sepsis; Shock, Septic; Species Specificity; Swine; Vasodilator Agents | 2003 |
A mouse model of argininosuccinic aciduria: biochemical characterization.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinic Acid; Argininosuccinic Aciduria; Carbamoyl-Phosphate Synthase (Ammonia); Cyclic GMP; Disease Models, Animal; Female; Genotype; Humans; Hyperammonemia; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Ornithine Carbamoyltransferase; Urea | 2003 |
[Influence of arginine on the renal functional condition of rats in sublimate nephropathy].
Topics: Animals; Arginine; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Kidney Function Tests; Male; Mercuric Chloride; Nephritis; Proteinuria; Rats; Uremia | 2002 |
Long-term dietary L-arginine supplementation attenuates proteinuria and focal glomerulosclerosis in experimental chronic renal transplant failure.
Topics: Animals; Arginine; Blood Pressure; Creatine; Dietary Supplements; Disease Models, Animal; Glomerulosclerosis, Focal Segmental; Kidney Failure, Chronic; Kidney Transplantation; Male; Nitrates; Nitrites; Proteinuria; Rats; Rats, Inbred F344 | 2003 |
L-Arginine increases ischemic injury in wild-type mice but not in iNOS-deficient mice.
Topics: Animals; Arginine; Brain Ischemia; Case-Control Studies; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Mice; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II | 2003 |
Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Arginine; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Imidazoles; Imipramine; Immobilization; Indazoles; Male; Mice; Mice, Inbred C57BL; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reaction Time; Swimming | 2003 |
Transient and ectopic expression of lumican by acinar cells in L-arginine-induced acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Arginine; Chondroitin Sulfate Proteoglycans; Disease Models, Animal; In Situ Hybridization; Keratan Sulfate; Lumican; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar | 2003 |
Effects of argatroban and heparin on thrombus formation and tissue plasminogen activator-induced thrombolysis in a microvascular thrombosis model.
Topics: Animals; Arginine; Cricetinae; Disease Models, Animal; Drug Interactions; Fibrinolytic Agents; Heparin; Mesocricetus; Microcirculation; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombolytic Therapy; Thrombosis; Time Factors; Tissue Plasminogen Activator | 2003 |
Hepatocellular dysfunction induced by nitric oxide production in hepatocytes isolated from rats with sepsis.
Topics: Adenosine Triphosphate; Animals; Arginine; Cecum; Disease Models, Animal; Enzyme Inhibitors; Hepatocytes; Humans; Interleukin-1; Intestinal Perforation; Ketone Bodies; Ligation; Liver Diseases; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Recombinant Proteins; Systemic Inflammatory Response Syndrome | 2003 |
Deletion of the Aspergillus fumigatus gene encoding the Ras-related protein RhbA reduces virulence in a model of Invasive pulmonary aspergillosis.
Topics: Animals; Arginine; Aspergillosis; Aspergillus fumigatus; Disease Models, Animal; Female; Fungal Proteins; Lung Diseases, Fungal; Mice; Monomeric GTP-Binding Proteins; Nitrogen; Sirolimus; Virulence | 2003 |
Effects of acute rejection on L-arginine/iNOS pathway in canine heart transplantation.
Topics: Animals; Arginine; Coronary Vessels; Dinoprost; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Graft Rejection; Heart Transplantation; Immunohistochemistry; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Potassium Chloride; Reperfusion Injury | 2003 |
Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end products and improve renal damage in a type 2 diabetic nephropathy rat model.
Topics: Animals; Antihypertensive Agents; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glycation End Products, Advanced; Hydralazine; Hypertension, Renal; Imidazoles; Immunohistochemistry; In Vitro Techniques; Kidney; Lipids; Lysine; Male; Olmesartan Medoxomil; Oxidation-Reduction; Proteinuria; Rats; Tetrazoles | 2003 |
Neuroprotective kappa-opioid receptor agonist BRL 52537 attenuates ischemia-evoked nitric oxide production in vivo in rats.
Topics: Animals; Arginine; Cerebral Infarction; Citrulline; Corpus Striatum; Disease Models, Animal; Ischemic Attack, Transient; Male; Microdialysis; Neuroprotective Agents; Nitric Oxide; Piperidines; Pyrrolidines; Rats; Rats, Wistar; Receptors, Opioid, kappa; Treatment Outcome | 2003 |
The effect of immunonutrition on bacterial translocation, and intestinal villus atrophy in experimental obstructive jaundice.
Topics: Animals; Arginine; Atrophy; Bacterial Translocation; Cholestasis, Extrahepatic; Disease Models, Animal; Enteral Nutrition; Fatty Acids, Omega-3; Glutamine; Intestinal Mucosa; Liver; Lymph Nodes; Male; Mesentery; Nutritional Physiological Phenomena; Random Allocation; Rats; Rats, Wistar; RNA; Spleen | 2003 |
[Mechanism of nitric oxide-dependent skin vasodilation during febrilysis].
Topics: Animals; Arginine; Body Temperature Regulation; Disease Models, Animal; Enzyme Inhibitors; Fever; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Skin; Vasodilation | 2003 |
Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis.
Topics: Animals; Arginase; Arginine; Asthma; Cytokines; Disease Models, Animal; Gene Expression Profiling; Genetic Markers; Humans; Isoenzymes; Lung; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitric Oxide; Oligonucleotide Array Sequence Analysis; RNA, Messenger; STAT6 Transcription Factor; Th2 Cells; Trans-Activators | 2003 |
Acute Chlamydia pneumoniae infection causes coronary endothelial dysfunction in pigs.
Topics: Acute Disease; Animals; Arginine; Bradykinin; Chlamydophila Infections; Chlamydophila pneumoniae; Coronary Circulation; Coronary Disease; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Glutathione; Nitric Oxide Synthase; Polymerase Chain Reaction; Probability; Reference Values; Swine; Vasoconstriction; Vasodilation | 2003 |
Effect of L-arginine and L-lysine on lysosomal hydrolases and membrane bound phosphatases in experimentally induced myocardial infarction in rats.
Topics: Animals; Arginine; Cell Membrane; Disease Models, Animal; Hydrolases; Isoproterenol; Lysine; Lysosomes; Male; Myocardial Infarction; Myocardium; Phosphoric Monoester Hydrolases; Rats; Rats, Wistar; Reference Values | 2003 |
Oral administration of L-arginine decreases blood pressure and increases renal excretion of sodium and water in renovascular hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Body Water; Disease Models, Animal; Diuresis; Hypertension, Renovascular; Male; Natriuresis; Rats; Rats, Wistar; Sodium | 2003 |
Argatroban attenuates leukocyte- and platelet-endothelial cell interactions after transient retinal ischemia.
Topics: Animals; Arginine; Blood Platelets; Cell Adhesion; Disease Models, Animal; Endothelium, Vascular; Gene Expression; Intercellular Adhesion Molecule-1; Ischemia; Leukocytes; Male; P-Selectin; Partial Thromboplastin Time; Pipecolic Acids; Platelet Aggregation Inhibitors; Prothrombin Time; Rats; Rats, Long-Evans; Reperfusion; Retina; Retinal Diseases; Retinal Vessels; RNA, Messenger; Sulfonamides; Thrombin; Treatment Outcome; Vascular Patency | 2003 |
[The role of nitric oxide in lung injury associated with acute necrotizing pancreatitis].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Female; Histocytochemistry; Lung; Lung Injury; Macrophages, Alveolar; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pancreatitis, Acute Necrotizing; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Pathogenesis of coxsackievirus A9 in mice: role of the viral arginine-glycine-aspartic acid motif.
Topics: Amino Acid Motifs; Animals; Animals, Newborn; Arginine; Aspartic Acid; Disease Models, Animal; Enterovirus B, Human; Enterovirus Infections; Glycine; In Situ Hybridization; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Mutation; Organ Specificity; Pancreas; RNA, Viral; Time Factors | 2003 |
A mouse model for cystinuria type I.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Basic; Amino Acids; Animals; Arginine; Carrier Proteins; Chromosome Mapping; Cystine; Cystinuria; Disease Models, Animal; Ethylnitrosourea; Female; Genotype; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C3H; Mice, Knockout; Molecular Sequence Data; Mutagenesis; Mutation; Ornithine; Phenotype; Sequence Homology, Amino Acid; Urinary Bladder Calculi; Urinary Calculi | 2003 |
[The effects of L-arginine and NG-nitro-L-arginine methylester on lipopolysaccharide and lipoteichoic acid induced liver injury in the rat].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Lipopolysaccharides; Liver; Liver Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Random Allocation; Rats; Rats, Wistar; Shock, Septic; Teichoic Acids | 2003 |
[The role of supplementation or inhibition of nitric oxide production in burn injury to reduce ischemic damage].
Topics: Animals; Arginine; Burns; Disease Models, Animal; Enzyme Inhibitors; Ischemia; Lipid Peroxidation; Lung; Lung Injury; Male; Malondialdehyde; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2003 |
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Chronic Disease; Disease Models, Animal; Enzyme Activation; Hypertension, Pulmonary; Hypoxia; Isoenzymes; Lung; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Sprague-Dawley | 2003 |
Effects of in vivo treatment with interleukins 1beta and 6 on rat mesenteric vascular bed reactivity.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electric Stimulation; Endothelin-1; Fever; Guanethidine; Inflammation; Interleukin-1; Interleukin-6; Intestinal Mucosa; Isomerism; Isoproterenol; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Norepinephrine; Perfusion; Rats; Rats, Sprague-Dawley; Sumatriptan; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation | 2003 |
Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.
Topics: Aging; Animals; Arginase; Arginine; Blood Vessels; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2003 |
Effect of L-arginine on overhydration and ultrastructure preservation of rat's heart exposed to cold cardioplegic ischaemia.
Topics: Animals; Arginine; Cardioplegic Solutions; Disease Models, Animal; Heart; Myocardial Ischemia; Myocardium; Organ Preservation; Rats; Water-Electrolyte Imbalance | 2003 |
Protective mechanism of L-arginine against liver ischemic-reperfusion injury in rats.
Topics: Alanine Transaminase; Analysis of Variance; Animals; Apoptosis; Arginine; Caspase 3; Caspases; Disease Models, Animal; Hepatocytes; In Situ Nick-End Labeling; Ischemia; Liver; Liver Function Tests; Male; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Survival Rate | 2003 |
Antithrombotic effects of FK419, a novel nonpeptide platelet GPIIb/IIIa antagonist, in a guinea pig photochemically induced middle cerebral artery thrombosis model: comparison with ozagrel and argatroban.
Topics: Animals; Antithrombins; Arginine; Blood Coagulation; Blood Platelets; Brain Ischemia; Disease Models, Animal; Guinea Pigs; Infarction, Middle Cerebral Artery; Male; Methacrylates; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Reperfusion Injury; Sulfonamides; Thromboxane B2 | 2004 |
L-arginine improves endothelial vasoreactivity and reduces thrombogenicity after thrombolysis in experimental deep venous thrombosis.
Topics: Animals; Arginine; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Fibrinolytic Agents; Nitric Oxide; Swine; Thrombolytic Therapy; Tissue Plasminogen Activator; Venous Thrombosis | 2003 |
[Influence of inhibitors of nitric oxide synthase and L-arginine on the survival rate in a rat model of traumatic shock].
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Shock, Traumatic; Survival Rate; Treatment Outcome | 2004 |
Augmentation of the NO-cGMP cascade induces anxiogenic-like effect in mice.
Topics: Animals; Anxiety; Arginine; Behavior, Animal; Carbolines; Cyclic GMP; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Male; Maze Learning; Mice; Motor Activity; Nitric Oxide; Piperazines; Purines; Sildenafil Citrate; Sulfones; Time Factors | 2003 |
Effects of L-arginine and NG-nitro L-arginine methyl ester on lipid peroxide, superoxide dismutase and nitrate levels after experimental sciatic nerve ischemia-reperfusion in rats.
Topics: Animals; Arginine; Disease Models, Animal; Female; Histological Techniques; Laparotomy; Lipid Peroxides; Male; Microscopy, Electron; Myelin Sheath; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Sciatic Nerve; Statistics, Nonparametric; Superoxide Dismutase; Time Factors | 2004 |
Impairment of fetal endothelium-dependent relaxation in a rat model of preeclampsia by chronic nitric oxide synthase inhibition.
Topics: Acetylcholine; Animals; Arginine; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Female; Fetus; Muscle Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; omega-N-Methylarginine; Potassium Chloride; Pre-Eclampsia; Pregnancy; Rats; Rats, Wistar; Vasodilation | 2004 |
Alteration of beta-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Nitric Oxide Synthase; Rats; Rats, Wistar | 2004 |
Comparative anti-inflammatory activities of antagonists to C3a and C5a receptors in a rat model of intestinal ischaemia/reperfusion injury.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Arginine; Australia; Benzhydryl Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Injections, Intravenous; Intestinal Mucosa; Membrane Proteins; Neutropenia; Neutrophils; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Anaphylatoxin C5a; Receptors, Complement; Reperfusion Injury; Time Factors | 2004 |
John M. Kinney International Award for Nutrition and Metabolism. Specific nutrient: role of arginine in sepsis.
Topics: Animals; Arginine; Awards and Prizes; China; Disease Models, Animal; Humans; Nutritional Physiological Phenomena; Parenteral Nutrition, Total; Rats; Sepsis | 2004 |
[Acute myocardial ischemia-reperfusion injury: role of nitric oxide system].
Topics: Acute Disease; Animals; Arginine; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Enzyme Inhibitors; Male; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine | 2004 |
Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Arginine; Cyclophosphamide; Cystitis; Disease Models, Animal; Enzyme Inhibitors; Female; Hemorrhage; Isothiuronium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2004 |
Gastroprotection by pentoxyfilline against stress-induced gastric damage. Role of lipid peroxidation, antioxidizing enzymes and proinflammatory cytokines.
Topics: Animals; Arginine; Cytokines; Disease Models, Animal; Free Radical Scavengers; Gastric Mucosa; Glutathione; Lipid Peroxidation; Lipid Peroxides; Male; Nitric Oxide Synthase; Pentoxifylline; Rats; Rats, Wistar; Regional Blood Flow; Restraint, Physical; Stomach; Stomach Diseases; Stress, Psychological; Superoxide Dismutase | 2004 |
17beta-estradiol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Cholesterol, LDL; Disease Models, Animal; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Estradiol; Male; Malondialdehyde; Nitric Oxide Synthase; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2004 |
Production of arginine by the kidney is impaired in a model of sepsis: early events following LPS.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Glomerular Filtration Rate; Kidney; Lipopolysaccharides; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrogen Oxides; Rats; Rats, Wistar; Sepsis | 2004 |
Do incremental increases in blood pressure elicit neointimal plaques through endothelial injury?
Topics: Aging; Animals; Aorta, Abdominal; Arginine; Blood Pressure; Chickens; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Hypertension; Male; Propranolol; Solvents; Tunica Intima | 2004 |
Influence of temporomandibular joint pain on sleep patterns: role of nitric oxide.
Topics: Animals; Arginine; Arthritis, Experimental; Disease Models, Animal; Enzyme Inhibitors; Facial Pain; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Wistar; Sleep Stages; Sleep Wake Disorders; Sleep, REM; Temporomandibular Joint Disorders; Time Factors | 2004 |
Laser Doppler flow and brain tissue PO2 after cortical impact injury complicated by secondary ischemia in rats treated with arginine.
Topics: Analysis of Variance; Animals; Arginine; Blood Flow Velocity; Blood Gas Analysis; Brain Chemistry; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Infusions, Intravenous; Intracranial Pressure; Laser-Doppler Flowmetry; Male; Nitric Oxide; Oxygen; Oxygen Consumption; Random Allocation; Rats; Rats, Long-Evans; Sodium Chloride; Time Factors | 2004 |
Nitric oxide modulation of early angiogenesis.
Topics: Analysis of Variance; Animals; Animals, Newborn; Arginine; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Muscle, Smooth, Vascular; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Probability; Reference Values; Sensitivity and Specificity; Wound Healing | 2004 |
In vivo administration of D-arginine: effects on blood pressure and vascular function in angiotensin II-induced hypertensive rats.
Topics: Angiotensin II; Animals; Aorta; Arginine; Disease Models, Animal; Hypertension; Male; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Stereoisomerism; Vascular Resistance | 2004 |
Antithrombotic effect of L-arginine in hypertensive rats.
Topics: Animals; Arginine; Disease Models, Animal; Fibrinolysis; Fibrinolytic Agents; Hemostasis; Hypertension; Kidney; Male; Platelet Aggregation; Rats; Rats, Wistar; Venous Thrombosis | 2004 |
Arginine and glutamine availability and macrophage functions in the obese insulin-resistant Zucker rat.
Topics: Animals; Arginine; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Genetic Predisposition to Disease; Glutamine; Immune System; Immunity, Innate; Infections; Insulin Resistance; Lipopolysaccharides; Macrophages; Male; Nitric Oxide; Obesity; Rats; Rats, Zucker; Signal Transduction; Tumor Necrosis Factor-alpha | 2005 |
Gut and liver handling of asymmetric and symmetric dimethylarginine in the rat under basal conditions and during endotoxemia.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Gastrointestinal Tract; Lipopolysaccharides; Liver; Male; Rats; Rats, Wistar; Regional Blood Flow; Splanchnic Circulation; Viscera | 2004 |
Peripheral involvement of the nitric oxide-cGMP pathway in the indomethacin-induced antinociception in rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Chronic Disease; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Gout; Indomethacin; Nerve Tissue Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Pain; Pain Measurement; Peripheral Nervous System; Rats; Rats, Wistar; Signal Transduction; Uric Acid | 2004 |
Association between cerebrospinal fluid levels of asymmetric dimethyl-L-arginine, an endogenous inhibitor of endothelial nitric oxide synthase, and cerebral vasospasm in a primate model of subarachnoid hemorrhage.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Macaca fascicularis; Middle Cerebral Artery; Nitric Oxide; Nitric Oxide Synthase; Subarachnoid Hemorrhage; Time Factors; Vasospasm, Intracranial | 2004 |
Activity of angiotensin-converting enzyme after treatment with L-arginine in renovascular hypertension.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Male; Nitric Oxide; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; Surgical Instruments | 2004 |
An alphaTropomyosin mutation alters dimer preference in nemaline myopathy.
Topics: Animals; Animals, Newborn; Arginine; Blotting, Northern; Blotting, Western; Dimerization; Disease Models, Animal; DNA Mutational Analysis; Gene Expression Regulation; Humans; Methionine; Mice; Mice, Transgenic; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Promoter Regions, Genetic; Protein Structure, Secondary; Recombinant Proteins; RNA, Messenger; Time Factors; Tropomyosin | 2005 |
Exogenous nitric oxide donor and related compounds protect against lung inflammatory response after hemorrhagic shock and resuscitation.
Topics: Animals; Arginine; Cytokines; Disease Models, Animal; Inflammation; Lung; Neutrophils; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Resuscitation; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha | 2004 |
Met proto-oncogene juxtamembrane rare variations in mouse and humans: differential effects of Arg and Cys alleles on mouse lung tumorigenesis.
Topics: Adenocarcinoma; Alleles; Amino Acid Sequence; Animals; Arginine; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplastic; Cysteine; Disease Models, Animal; DNA Mutational Analysis; Genetic Linkage; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Mice; Mice, Inbred Strains; Molecular Sequence Data; Multifactorial Inheritance; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Receptors, Growth Factor; Receptors, Thrombin; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Oral arginine improves intestinal recovery following ischemia-reperfusion injury in rat.
Topics: Administration, Oral; Animals; Apoptosis; Arginine; Cell Count; Cell Proliferation; Disease Models, Animal; Enterocytes; Intestinal Diseases; Intestinal Mucosa; Intestine, Small; Ligation; Male; Mesenteric Artery, Superior; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Treatment Outcome | 2005 |
Arginine supplementation improves rotorod performance in sickle transgenic mice.
Topics: Anemia, Sickle Cell; Animals; Arginine; Diet; Disease Models, Animal; Hemoglobin A; Hemoglobin, Sickle; Homozygote; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nitric Oxide; Vasodilation | 2004 |
The role of nitric oxide in iron-induced rat renal injury.
Topics: Animals; Arginine; Deferoxamine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Iron; Iron Chelating Agents; Iron Overload; Kidney; Kidney Diseases; Kidney Function Tests; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Vitamin E | 2004 |
l-Arginine attenuates acute pulmonary embolism-induced oxidative stress and pulmonary hypertension.
Topics: Acute Disease; Animals; Arginine; Dextrans; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Pulmonary; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Pulmonary Artery; Pulmonary Embolism; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2005 |
Suppression of ethanol self-administration by the neuropeptide Y (NPY) Y2 receptor antagonist BIIE0246: evidence for sensitization in rats with a history of dependence.
Topics: Alcoholism; Animals; Arginine; Benzazepines; Brain; Brain Chemistry; Disease Models, Animal; Ethanol; Male; Neuropeptide Y; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Self Administration | 2005 |
Preoperative supplementation with a carbohydrate mixture decreases organ dysfunction-associated risk factors.
Topics: Alanine Transaminase; Animals; Arginine; Blood Urea Nitrogen; Dietary Carbohydrates; Dietary Supplements; Disease Models, Animal; Glutathione; Glycogen; Interleukin-6; Liver; Male; Multiple Organ Failure; Preoperative Care; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Risk Factors | 2005 |
Cyclooxygenase-2 plays a central role in the genesis of pancreatitis and associated lung injury.
Topics: Animals; Arginine; Biopsy, Needle; Blotting, Western; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Immunohistochemistry; Lung Diseases; Lung Injury; Male; Pancreatitis; Probability; Prostaglandin-Endoperoxide Synthases; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Risk Factors; Sensitivity and Specificity; Statistics, Nonparametric; Up-Regulation | 2005 |
[Inhibitors of arginase pathway in L-arginine metabolism as a new class of antihypertensive drugs: action of urea on oxidative and nonoxidative metabolism of L-arginine and vascular tone in chronic hypertension].
Topics: Animals; Antihypertensive Agents; Aorta; Arginase; Arginine; Disease Models, Animal; Enzyme Inhibitors; Erythrocytes; Heart; Hypertension; Myocardium; Nitric Oxide; Oxidation-Reduction; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Urea | 2004 |
Antithrombotic potential of new direct thrombin inhibitors built on the azaphenylalanine scaffold in two rat venous thrombosis models.
Topics: Administration, Oral; Animals; Anticoagulants; Arginine; Blood Coagulation Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fibrinolytic Agents; Injections, Subcutaneous; Male; Nadroparin; Phenylalanine; Pipecolic Acids; Rats; Rats, Wistar; Structure-Activity Relationship; Sulfonamides; Thrombin; Thrombophilia; Vena Cava, Inferior; Venous Thrombosis | 2005 |
Counteraction of oxalate induced nitrosative stress by supplementation of l-arginine, a potent antilithic agent.
Topics: Animals; Antioxidants; Arginine; Body Weight; Dietary Supplements; Disease Models, Animal; Ethylene Glycol; Free Radicals; Hyperoxaluria; Kidney; L-Lactate Dehydrogenase; Liver; Male; Nitrosation; Oxalates; Oxidative Stress; Oxidoreductases; Rats; Rats, Wistar; Uricosuric Agents; Urinary Calculi | 2005 |
Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Drug Evaluation, Preclinical; Electrophoretic Mobility Shift Assay; Enteral Nutrition; Glutamine; Immunity, Mucosal; Immunologic Factors; Inflammation; Jejunum; Male; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Patient Selection; Peroxisome Proliferator-Activated Receptors; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Risk Factors; Time Factors; Transcription Factor AP-1 | 2005 |
Effects of altered amygdalar neuropeptide Y expression on anxiety-related behaviors.
Topics: Amygdala; Animals; Anti-Anxiety Agents; Anxiety; Arginine; Behavior, Animal; Disease Models, Animal; DNA, Antisense; Gene Expression Regulation; Genetic Vectors; Immunohistochemistry; Male; Maze Learning; Neuropeptide Y; Rats; Rats, Long-Evans; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2005 |
[Role of nitric oxide and lipid peroxidation in pathogenesis of acute experimental pancreatitis].
Topics: Animals; Arginine; Disease Models, Animal; Lipid Peroxidation; Lipid Peroxides; Male; Methylene Blue; Nitrates; Nitric Oxide; Nitrites; Pancreatitis, Acute Necrotizing; Rats; Rats, Wistar | 2005 |
[The influence of L-arginine on secretion of nitric oxide and haemodynamic function of isolated rat's heart subjected to cold cardioplegic ischemia and reperfusion].
Topics: Animals; Arginine; Cardioplegic Solutions; Cold Temperature; Disease Models, Animal; Free Radical Scavengers; Heart; Heart Arrest, Induced; Hemodynamics; In Vitro Techniques; Myocardium; Nitric Oxide; Oxygen Consumption; Rats; Rats, Wistar; Reperfusion | 2004 |
Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.
Topics: Animals; Animals, Newborn; Arginine; Blotting, Western; Brain; Cells, Cultured; Cerebellum; Cricetinae; Cricetulus; Detergents; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Gene Expression; Glial Fibrillary Acidic Protein; Golgi Apparatus; Golgi Matrix Proteins; Immunoprecipitation; Leucine; Membrane Proteins; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurodegenerative Diseases; Neurons; Octoxynol; Prion Diseases; Protein Structure, Tertiary; PrPSc Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfur Isotopes; Time Factors; Type C Phospholipases; Valine | 2005 |
Increased levels and reduced catabolism of asymmetric and symmetric dimethylarginines in pulmonary hypertension.
Topics: Amidohydrolases; Animals; Arginine; Disease Models, Animal; Humans; Hypertension, Pulmonary; Isoenzymes; Lung; Male; Monocrotaline; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2005 |
Effect of L-arginine on collagen of high flow-induced pulmonary arterial remodeling.
Topics: Animals; Arginine; Collagen Type I; Collagen Type III; Disease Models, Animal; Hypertension, Pulmonary; Male; Pulmonary Artery; Rats; Rats, Sprague-Dawley | 2005 |
Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis.
Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Arginine; Biomarkers; CD11b Antigen; CD2 Antigens; Cyclic GMP; DEET; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Encephalomyelitis, Autoimmune, Experimental; Female; Guanylate Cyclase; Guinea Pigs; Hydrazines; Immunohistochemistry; Macrophages; Microscopy, Electron, Transmission; Myelin Basic Protein; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Optic Chiasm; Optic Nerve; Ornithine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred Lew; Time Factors | 2005 |
Parenteral arginine impairs intestinal adaptation following massive small bowel resection in a rat model.
Topics: Adaptation, Physiological; Animals; Apoptosis; Arginine; Cell Proliferation; Disease Models, Animal; Enterocytes; Ileum; Injections, Subcutaneous; Intestines; Jejunum; Male; Organ Size; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome | 2005 |
ADMA regulates angiogenesis: genetic and metabolic evidence.
Topics: Animals; Arginine; Blotting, Western; Disease Models, Animal; Female; Hypercholesterolemia; Ischemia; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neovascularization, Physiologic; Nitric Oxide Synthase | 2005 |
l-Arginine attenuates cardiovascular impairment in DOCA-salt hypertensive rats.
Topics: Action Potentials; Animals; Aorta, Thoracic; Arginine; Cardiomegaly; Desoxycorticosterone; Disease Models, Animal; Echocardiography; Hypertension, Renal; Male; Microelectrodes; Nephrectomy; Papillary Muscles; Rats; Rats, Wistar; Sodium Chloride | 2005 |
Profile of gene expression in a murine model of allergic bronchopulmonary aspergillosis.
Topics: Animals; Arginine; Aspergillosis, Allergic Bronchopulmonary; Chemokines; Cytokines; Disease Models, Animal; Gene Expression Profiling; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Receptors, Cell Surface; Signal Transduction; Toll-Like Receptors | 2005 |
Intravenous antioxidant modulation of end-organ damage in L-arginine-induced experimental acute pancreatitis.
Topics: Acetylcysteine; Acute Disease; Amylases; Animals; Antioxidants; Arginine; Ascorbic Acid; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Therapy, Combination; Injections, Intravenous; Lung; Male; Pancreas; Pancreatitis; Peroxidase; Proteins; Rats; Rats, Sprague-Dawley; Selenium; Time Factors | 2005 |
Vascular effects of the human extracellular superoxide dismutase R213G variant.
Topics: Amino Acid Substitution; Animals; Arginine; Diabetic Nephropathies; Disease Models, Animal; Gene Transfer Techniques; Glycine; Humans; Kidney Failure, Chronic; Male; Myocardial Ischemia; Polymorphism, Single Nucleotide; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Recombinant Proteins; Superoxide Dismutase | 2005 |
Neuroprotective effect of L-arginine in a newborn rat model of acute severe asphyxia.
Topics: Animals; Animals, Newborn; Arginine; Asphyxia; Brain; Carotid Arteries; Disease Models, Animal; Hypoxia-Ischemia, Brain; Ligation; Nerve Degeneration; Neurons; Neuroprotective Agents; Rats; Rats, Wistar | 2005 |
Effects of potassium channel inhibitors in the forced swimming test: possible involvement of L-arginine-nitric oxide-soluble guanylate cyclase pathway.
Topics: Analysis of Variance; Animals; Arginine; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escape Reaction; Exploratory Behavior; Female; Guanylate Cyclase; Immobility Response, Tonic; Injections, Intraventricular; Mice; Motor Activity; Nitric Oxide; Nitric Oxide Donors; Piperazines; Potassium Channel Blockers; Potassium Channels; Purines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Sildenafil Citrate; Soluble Guanylyl Cyclase; Statistics, Nonparametric; Stress, Psychological; Sulfones; Swimming | 2005 |
L-arginine improves dystrophic phenotype in mdx mice.
Topics: Animals; Arginine; Creatine Kinase; Diaphragm; Disease Models, Animal; Dystroglycans; Evans Blue; Female; Isometric Contraction; Magnetic Resonance Imaging; Mice; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Animal; Necrosis; Nitric Oxide Donors; Phenotype; Recovery of Function; Treatment Outcome; Utrophin | 2005 |
Acute subdural hematoma: new model delineation and effects of coagulation inhibitors.
Topics: Animals; Anticoagulants; Arginine; Behavior, Animal; Disease Models, Animal; Diterpenes; Extremities; Fibrinolytic Agents; Ginkgolides; Hematoma, Subdural, Acute; Lactones; Male; Movement; Pipecolic Acids; Psychomotor Performance; Rats; Reproducibility of Results; Sulfonamides; Time Factors | 2005 |
L-Arginine prevents air embolism-induced acute lung injury in rats.
Topics: Acute Disease; Animals; Arginine; Bronchoalveolar Lavage; Capillary Permeability; Disease Models, Animal; Embolism, Air; Hypertension, Pulmonary; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Organ Size; Proteins; Pulmonary Edema; Random Allocation; Rats; Rats, Sprague-Dawley | 2005 |
Effects of L-arginine on the endogenous angiogenic response in a model of hypercholesterolemia.
Topics: Animals; Arginine; Blotting, Western; Cholesterol; Coronary Artery Disease; Coronary Circulation; Disease Models, Animal; Hypercholesterolemia; Microcirculation; Myocardial Contraction; Neovascularization, Physiologic; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Swine; Swine, Miniature; Vasodilation | 2005 |
Characterization of the action of S 21403 (mitiglinide) on insulin secretion and biosynthesis in normal and diabetic beta-cells.
Topics: Animals; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Gerbillinae; Glucose; Hypoglycemic Agents; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Isoindoles; Perfusion; Rats; Rats, Wistar | 2005 |
[Study on the mechanism of protective effect of oral L-arginine on intestine after scald injury in rats].
Topics: Animals; Arginine; Burns; Disease Models, Animal; Endothelins; Feeding Methods; Intestinal Mucosa; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2005 |
Intravenous selenium modulates L-arginine-induced experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Antioxidants; Arginine; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Edema; Injections, Intravenous; Lung; Male; Oxidative Stress; Pancreas; Pancreatitis; Peroxidase; Rats; Rats, Sprague-Dawley; Selenium; Serum Albumin | 2005 |
In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy.
Topics: Animals; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diet, Fat-Restricted; Disease Models, Animal; Female; Follow-Up Studies; Glycation End Products, Advanced; Immunohistochemistry; Kidney; Lysine; Male; Microscopy, Electron; Obesity; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Wistar | 2005 |
Secondhand tobacco smoke impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle: improvement with chronic oral administration of L-arginine.
Topics: Administration, Oral; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelium, Vascular; Male; Muscle Relaxation; Muscle, Smooth; Penis; Rabbits; Reference Values; Risk Factors; Sensitivity and Specificity; Tobacco Smoke Pollution | 2005 |
Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering.
Topics: Analysis of Variance; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biopsy, Needle; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Hypertension, Renal; Immunohistochemistry; In Vitro Techniques; Kidney; Lysine; Male; Rats; Rats, Inbred SHR; Sensitivity and Specificity; Statistics, Nonparametric | 2005 |
Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.
Topics: Animals; Antioxidants; Arginine; Bone Marrow Transplantation; Disease Models, Animal; Fluorescent Antibody Technique; Hindlimb; Ischemia; Mice; Neovascularization, Pathologic; Nitrates; Nitrites; Oxidative Stress; Transplantation, Autologous | 2005 |
Attenuated insulin release and storage in fetal sheep pancreatic islets with intrauterine growth restriction.
Topics: Animals; Arginine; Body Temperature; Catecholamines; Disease Models, Animal; Female; Fetal Growth Retardation; Glucagon; Glucose; Hydrocortisone; Insulin; Islets of Langerhans; Norepinephrine; Organ Size; Oxygen; Potassium Chloride; Pregnancy; Pregnancy, Animal; Sheep | 2006 |
Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats.
Topics: Animals; Arginine; Behavior, Animal; Cold Temperature; Constriction, Pathologic; Disease Models, Animal; Hindlimb; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Male; Neuralgia; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pain Threshold; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sciatic Nerve; Stress, Mechanical | 2006 |
Immune-enhancing diet and cytokine expression during chronic sepsis: an immune-enhancing diet containing L-arginine, fish oil, and RNA fragments promotes intestinal cytokine expression during chronic sepsis in rats.
Topics: Animals; Arginine; Bacteroides fragilis; Bacteroides Infections; Chronic Disease; Cytokines; Dietary Fats; Disease Models, Animal; Escherichia coli Infections; Fish Oils; Food, Formulated; Immunoglobulin A; Immunoglobulin Class Switching; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-5; Interleukin-6; Intestine, Small; Male; Random Allocation; Rats; Rats, Sprague-Dawley; RNA; Sepsis; Tumor Necrosis Factor-alpha | 2006 |
Evidence for the involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Arginine; Cyclic GMP; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Immobility Response, Tonic; Male; Memantine; Mice; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Penicillamine; Piperazines; Purines; Sildenafil Citrate; Sulfones; Swimming | 2006 |
Effects of local gene transfer of VEGF on neointima formation after balloon injury in hypercholesterolemic rabbits.
Topics: Angioplasty, Balloon; Animals; Arginine; Dietary Fats; Disease Models, Animal; Humans; Hypercholesterolemia; Iliac Artery; Male; Plasmids; Rabbits; Transfection; Tunica Intima; Vascular Endothelial Growth Factor A | 2005 |
Calcitonin gene-related peptide partially mediates nociception in acute experimental pancreatitis.
Topics: Acute Disease; Animals; Arginine; Calcitonin Gene-Related Peptide; Disease Models, Animal; Male; Necrosis; Pain; Pancreatitis; Posterior Horn Cells; Rats; Rats, Sprague-Dawley | 2006 |
A highly attenuated rabies virus HEP-Flury strain reverts to virulent by single amino acid substitution to arginine at position 333 in glycoprotein.
Topics: Amino Acid Substitution; Animals; Antibodies, Viral; Antigens, Viral; Arginine; Brain; Disease Models, Animal; Glycoproteins; Mice; Mutation; Neutralization Tests; Rabies; Rabies virus; Rats; Suppression, Genetic; Survival Analysis; Viral Envelope Proteins | 2006 |
Anti-inflammatory effect of augmented nitric oxide production in chronic lung infection.
Topics: Animals; Arginine; Bronchoalveolar Lavage Fluid; Cell Count; Chronic Disease; Disease Models, Animal; Enzyme Inhibitors; Interleukin-1; Interleukin-6; Lung; Lung Diseases; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pseudomonas Infections; Rats; Rats, Inbred WKY; Tyrosine; Vascular Endothelial Growth Factor A | 2006 |
Is nitric oxide involved in the antinociceptive activity of tramadol? Findings in a rat model of neuropathic pain.
Topics: Analgesics; Animals; Arginine; Disease Models, Animal; Injections, Intraperitoneal; Male; Nerve Compression Syndromes; Neuralgia; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nociceptors; Rats; Rats, Wistar; Tramadol | 2005 |
Blunted non-nitric oxide vasodilatory neurotransmission in penile arteries from renal hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Arginine; Arteries; Bendroflumethiazide; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension, Renal; Male; Neurotransmitter Agents; Nitric Oxide; Penis; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Early activation of endoplasmic reticulum stress is associated with arginine-induced acute pancreatitis.
Topics: Animals; Arginine; Cytokines; Disease Models, Animal; Endoplasmic Reticulum; Male; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Wistar | 2006 |
The degree of oxidative stress in the rat brain during ischemia and reperfusion in conditions of correction of the L-arginine-NO system.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Enzyme Inhibitors; Lipid Peroxidation; Male; Nitric Oxide; Oxidative Stress; Rats; Reperfusion Injury; Vitamins | 2006 |
Seasonal differences in activities of rabbit liver tRNA and aminoacyl-tRNA synthetases specific for valine and arginine under myocardial ischemia.
Topics: Acute Disease; Amino Acyl-tRNA Synthetases; Animals; Arginine; Disease Models, Animal; Liver; Male; Myocardial Ischemia; Protein Biosynthesis; Rabbits; RNA, Transfer; Seasons; Time Factors; Valine | 2006 |
Nitric oxide and liver microcirculation during autoregulation and haemorrhagic shock in rabbit model.
Topics: Anilides; Animals; Arginine; Blood Pressure; Carbon Dioxide; Disease Models, Animal; Hepatic Artery; Homeostasis; Infusions, Intravenous; Liver; Microcirculation; Models, Animal; Nitric Oxide; Nitric Oxide Synthase; Oxygen; Rabbits; Shock, Hemorrhagic | 2006 |
Effects of vasopressin, norepinephrine, and L-arginine on intestinal microcirculation in endotoxemia.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Endotoxemia; Escherichia coli Infections; Female; Ileum; Mice; Mice, Inbred BALB C; Microcirculation; Norepinephrine; Vasoconstrictor Agents; Vasopressins | 2006 |
Influence of nitric oxide on morphine-induced amnesia and interactions with dopaminergic receptor agents.
Topics: Amnesia; Analysis of Variance; Animals; Arginine; Avoidance Learning; Behavior, Animal; Disease Models, Animal; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Male; Mice; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Reaction Time | 2006 |
L-NAME prevents anxiety-like and depression-like behavior in rats exposed to restraint stress.
Topics: Acute Disease; Animals; Anxiety; Arginine; Chronic Disease; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological | 2006 |
Proteomics implicates peptidyl arginine deiminase 2 and optic nerve citrullination in glaucoma pathogenesis.
Topics: Aged; Aged, 80 and over; Animals; Arginine; Astrocytes; Blotting, Western; Citrulline; Disease Models, Animal; Down-Regulation; Female; Glaucoma, Open-Angle; Humans; Hydrolases; Immunohistochemistry; Male; Methylation; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Middle Aged; Optic Nerve Diseases; Proteomics; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2006 |
Neuropeptide Y Y1 receptors mediate morphine-induced reductions of natural killer cell activity.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Anti-Anxiety Agents; Arginine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Immune Tolerance; Killer Cells, Natural; Male; Morphine; Morphine Dependence; Narcotics; Neuroimmunomodulation; Neuropeptide Y; Nucleus Accumbens; Rats; Rats, Inbred Lew; Receptors, Dopamine D1; Receptors, Neuropeptide Y; Spleen; Sympathetic Nervous System | 2006 |
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Disease Models, Animal; Factor V; Ferric Compounds; Gene Frequency; Glutamine; Homozygote; Mice; Mice, Inbred C57BL; Mutation; Thrombosis; Venous Thrombosis | 2007 |
Arginine 54 and Tyrosine 118 residues of {alpha}A-crystallin are crucial for lens formation and transparency.
Topics: Actins; alpha-Crystallin A Chain; Animals; Arginine; Cataract; Chromosome Mapping; Disease Models, Animal; Electrophoresis, Gel, Two-Dimensional; Epithelial Cells; Female; Genes, Dominant; Genes, Recessive; Genetic Linkage; Green Fluorescent Proteins; Lens, Crystalline; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mitochondria; Phenotype; Point Mutation; Tyrosine | 2006 |
The effect of L-arginine methyl ester on indices of free radical involvement in a rat model of experimental nephrocalcinosis.
Topics: Animals; Arginine; Blood Urea Nitrogen; Calcium Oxalate; Catalase; Creatinine; Crystallization; Disease Models, Animal; Enzyme Inhibitors; Free Radicals; Glutathione; Magnesium; Male; Nephrocalcinosis; NG-Nitroarginine Methyl Ester; Oxidative Stress; Potassium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium; Superoxide Dismutase; Uric Acid | 2006 |
Therapeutic effects of concurrent autologous bone marrow cell infusion and metabolic intervention in ischemia-induced angiogenesis in the hypercholesterolemic mouse hindlimb.
Topics: Animals; Antioxidants; Apolipoproteins E; Arginine; Bone Marrow Transplantation; Combined Modality Therapy; Disease Models, Animal; Hindlimb; Hypercholesterolemia; Ischemia; Laser-Doppler Flowmetry; Macrophages; Male; Mice; Mice, Knockout; Neovascularization, Physiologic; Nitric Oxide; Oxidative Stress; Peripheral Vascular Diseases; Regional Blood Flow; Transplantation, Autologous; Ultrasonography | 2007 |
Nicotine-induced changes of glutamate and arginine in naive and chronically alcoholized rats: an in vivo microdialysis study.
Topics: Alcohol-Induced Disorders, Nervous System; Animals; Arginine; Brain Chemistry; Central Nervous System Depressants; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Ethanol; Extracellular Fluid; Glutamic Acid; Male; Microdialysis; Nicotine; Nicotinic Agonists; Nitric Oxide; Nucleus Accumbens; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Tobacco Use Disorder | 2006 |
Arginine-enriched diet limits plasma and muscle glutamine depletion in head-injured rats.
Topics: Animals; Arginine; Craniocerebral Trauma; Disease Models, Animal; Enteral Nutrition; Glutamine; Male; Muscle, Skeletal; Nutritional Requirements; Random Allocation; Rats; Rats, Sprague-Dawley | 2006 |
Characterization of cationic amino acid transport systems in rat erythrocytes: lack of effect of uraemia on L-arginine influx.
Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Animals; Arginine; Citrulline; Disease Models, Animal; Erythrocytes; Kinetics; Leucine; Lysine; Male; Nephrectomy; Ornithine; Rats; Rats, Wistar; Uremia | 2006 |
Role of the L-citrulline/L-arginine cycle in iNANC nerve-mediated nitric oxide production and airway smooth muscle relaxation in allergic asthma.
Topics: Allergens; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Asthma; Citrulline; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; N-Methylaspartate; Neural Inhibition; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Ovalbumin; Specific Pathogen-Free Organisms; Succinic Acid; Trachea | 2006 |
Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arginine; Capsaicin; Chlorocebus aethiops; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Female; Glycine; Inflammation; Ion Channels; Male; Mice; Mice, Inbred ICR; Nociceptors; Oocytes; Pain; Patch-Clamp Techniques; Rats; Rats, Wistar; Sensory Receptor Cells; TRPV Cation Channels; Xenopus | 2006 |
Ryanodine receptor type 1 (RyR1) possessing malignant hyperthermia mutation R615C exhibits heightened sensitivity to dysregulation by non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95).
Topics: Animals; Arginine; Calcium; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; In Vitro Techniques; Inhibitory Concentration 50; Malignant Hyperthermia; Muscle, Skeletal; Mutation; Polychlorinated Biphenyls; Protein Binding; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Swine; Tritium | 2007 |
Ventricular fibrillation induced by ischemia-reperfusion is not prevented by the NPY Y2 receptor antagonist BIIE0246.
Topics: Animals; Arginine; Benzazepines; Biomarkers; Blood Pressure; Body Temperature; Carbon Dioxide; Cardiac Output; Coronary Circulation; Coronary Stenosis; Disease Models, Animal; Female; Heart Rate; Hematocrit; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Oxygen; Potassium; Receptors, Neuropeptide Y; Swine; Tachycardia, Ventricular; Ventricular Fibrillation | 2006 |
Characterisation of a transgenic mouse expressing R122H human cationic trypsinogen.
Topics: Amylases; Animals; Arginine; Ceruletide; Cytokines; Disease Models, Animal; DNA; Histidine; Humans; Lipase; Mice; Mice, Transgenic; Mutation; Pancreas; Pancreatitis; Phenotype; RNA, Messenger; Secretory Vesicles; Severity of Illness Index; Time Factors; Transgenes; Trypsin; Trypsinogen | 2006 |
The involvement of nitric oxide in the anticonvulsant effects of alpha-tocopherol on penicillin-induced epileptiform activity in rats.
Topics: alpha-Tocopherol; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillins; Rats; Rats, Wistar; Seizures | 2007 |
Protease-activated receptor-2 protects against pancreatitis by stimulating exocrine secretion.
Topics: Acute Disease; Amylases; Animals; Arginine; Ceruletide; Disease Models, Animal; Enzyme Activation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pancreas, Exocrine; Pancreatitis; Receptor, PAR-2; RNA, Messenger; Tissue Culture Techniques; Transcription Factors; Trypsin; Up-Regulation | 2007 |
The effect of L-arginine on neointimal proliferation and artery remodeling on an iliac artery lesion caused by a balloon catheter in hypercholesterolemic rabbits.
Topics: Angioplasty, Balloon; Animals; Arginine; Disease Models, Animal; Endothelium, Vascular; Hypercholesterolemia; Iliac Artery; Male; Rabbits; Tunica Intima | 2006 |
Protective effect of arginine on oxidative stress in transgenic sickle mouse models.
Topics: Anemia, Sickle Cell; Animals; Antioxidants; Arginine; Catalase; Dietary Supplements; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Mice; Mice, Inbred C57BL; Mice, Transgenic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Superoxide Dismutase | 2006 |
Development of a new mouse model of acute pancreatitis induced by administration of L-arginine.
Topics: Acute Disease; Amylases; Animals; Arginine; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Fibrosis; Injections, Intraperitoneal; Lung; Lung Diseases; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pancreas; Pancreatitis; Peroxidase; Reproducibility of Results; Severity of Illness Index; Time Factors; Trypsin | 2007 |
Arginine uptake is attenuated, through post-translational regulation of cationic amino acid transporter-1, in hyperlipidemic rats.
Topics: Animals; Aorta; Arginine; Cationic Amino Acid Transporter 1; Diet, Atherogenic; Disease Models, Animal; Endothelium; Gene Expression Regulation; Hypercholesterolemia; Male; Nitric Oxide Synthase; Protein Processing, Post-Translational; Rats; Rats, Wistar | 2007 |
Role of nitric oxide in urinary bladder function: effect of L-arginine.
Topics: Animals; Arginine; Blood Flow Velocity; Disease Models, Animal; Male; Nitric Oxide; Rabbits; Treatment Outcome; Urinary Bladder; Urinary Bladder Neck Obstruction | 2007 |
Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Arginine; Bone Marrow Cells; Bone Resorption; CD11b Antigen; Cell Differentiation; Cherubism; Disease Models, Animal; Hematologic Diseases; Homozygote; Inflammation; Intracellular Signaling Peptides and Proteins; Lymph Nodes; Macrophage Colony-Stimulating Factor; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Myeloid Cells; Osteoclasts; Phosphorylation; Proline; Protein-Tyrosine Kinases; RANK Ligand; Spleen; Syk Kinase; Tumor Necrosis Factor-alpha | 2007 |
The amino acid L-lysine blocks the disruptive effect of phencyclidine on prepulse inhibition in mice.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Animals; Arginine; Behavior, Animal; Biological Transport; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Hallucinogens; Lysine; Male; Mice; Nitric Oxide; Phencyclidine; Reflex; Reflex, Startle; Schizophrenia | 2007 |
Infusion of neuropeptide Y into CA3 region of hippocampus produces antidepressant-like effect via Y1 receptor.
Topics: Animals; Antidepressive Agents; Arginine; Avoidance Learning; Behavior, Animal; Benzazepines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Helplessness, Learned; Hippocampus; Injections, Intraventricular; Male; Neuropeptide Y; Peptide YY; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, G-Protein-Coupled; Receptors, Neuropeptide | 2007 |
Role of nitric oxide-producing and -degrading pathways in coronary endothelial dysfunction in chronic kidney disease.
Topics: Acetylcholine; Amidohydrolases; Animals; Arginine; Coronary Circulation; Disease Models, Animal; Dogs; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Glomerular Filtration Rate; Kidney Failure, Chronic; Male; Microscopy, Video; Nitric Oxide; Nitric Oxide Synthase Type III; Nitroprusside; Tretinoin; Vasodilation; Vasodilator Agents | 2007 |
Role of nitric oxide in the development of distant metastasis from squamous cell carcinoma.
Topics: Animals; Arginine; Carcinoma, Squamous Cell; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Shape; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Enzyme Inhibitors; Fluorescent Dyes; Head and Neck Neoplasms; Humans; Interleukin-1; Liver Circulation; Mice; Mice, Inbred BALB C; Mice, Nude; Microcirculation; Microscopy, Video; Muscle, Skeletal; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Nude | 2007 |
Synergistic therapeutic potential of dexamethasone and L-arginine in lipopolysaccharide-induced septic shock.
Topics: Alanine Transaminase; Animals; Arginase; Arginine; Aspartate Aminotransferases; Cytokines; Dexamethasone; Disease Models, Animal; Drug Synergism; Glucocorticoids; HSP70 Heat-Shock Proteins; Lipopolysaccharides; Liver; Male; Mice; Mice, Inbred Strains; Nitric Oxide Synthase Type II; Nitrites; Shock, Septic; Survival Rate | 2007 |
Ursodesoxycholic acid and heme-arginate are unable to improve hematopoiesis and liver injury in an erythropoietic protoporphyria mouse model.
Topics: Animals; Arginine; Cholagogues and Choleretics; Disease Models, Animal; Hematopoiesis; Heme; Injections, Intraperitoneal; Liver; Mice; Mice, Transgenic; Protoporphyria, Erythropoietic; Ursodeoxycholic Acid | 2006 |
The impact of arginine on bacterial translocation in an intestinal obstruction model in rats.
Topics: Animals; Arginine; Bacterial Translocation; Disease Models, Animal; Dose-Response Relationship, Drug; Enteral Nutrition; Escherichia coli; Fatty Acids, Omega-3; Humans; Intestinal Obstruction; Liver; Lung; Lymph Nodes; Male; Nutritional Physiological Phenomena; Random Allocation; Rats; Rats, Wistar; RNA; Spleen; Technetium | 2007 |
Rheolytic pharmacomechanical thrombectomy in experimental chronic deep vein thrombosis: effect of L-arginine on thrombogenicity and endothelial vasomotor function.
Topics: Adenosine Diphosphate; Angiography; Animals; Arginine; Bradykinin; Calcimycin; Disease Models, Animal; Endosonography; Endothelium, Vascular; Microscopy, Electron, Scanning; Nitroprusside; Serotonin; Swine; Thrombectomy; Venous Thrombosis | 2007 |
Role of combined L-arginine and prostaglandin E1 in renal ischemia-reperfusion injury.
Topics: Alprostadil; Animals; Arginine; Creatinine; Disease Models, Animal; Drug Therapy, Combination; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sodium; Survival Analysis; Urine; Vasodilator Agents | 2007 |
Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Hemorrhage; Injections, Spinal; Nitric Oxide; Oxadiazoles; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Sympathetic Nervous System | 2007 |
Dimethylarginine dimethylaminohydrolase promotes endothelial repair after vascular injury.
Topics: Amidohydrolases; Animals; Arginine; Cell Proliferation; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Femoral Artery; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neovascularization, Physiologic; Nitric Oxide; Probability; Random Allocation; Sensitivity and Specificity; Species Specificity; Vascular Diseases | 2007 |
Slc7a7 disruption causes fetal growth retardation by downregulating Igf1 in the mouse model of lysinuric protein intolerance.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Transport System y+; Amino Acid Transport System y+L; Animals; Arginine; Dietary Proteins; Disease Models, Animal; Down-Regulation; Fetal Growth Retardation; Gene Expression; Gene Expression Profiling; Genotype; Insulin-Like Growth Factor I; Intestinal Mucosa; Intestines; Liver; Lysine; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Phenotype; Polymerase Chain Reaction; Urea | 2007 |
Dimethylarginine dimethylaminohydrolase prevents progression of renal dysfunction by inhibiting loss of peritubular capillaries and tubulointerstitial fibrosis in a rat model of chronic kidney disease.
Topics: Amidohydrolases; Animals; Arginine; Capillaries; Chronic Disease; Disease Models, Animal; Disease Progression; Fibrosis; Gene Expression Regulation, Enzymologic; Genetic Therapy; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2007 |
TNF-alpha contributes to endothelial dysfunction by upregulating arginase in ischemia/reperfusion injury.
Topics: Acetylcholine; Animals; Arginase; Arginine; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Mice; Mice, Knockout; Mice, Transgenic; Myocardial Reperfusion Injury; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxidase; Receptors, Tumor Necrosis Factor; RNA, Messenger; Superoxides; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2007 |
Myocardial release of nitric oxide during ischaemia and reperfusion: effects of L-arginine and hypercholesterolaemia.
Topics: Analysis of Variance; Animals; Arginine; Coronary Circulation; Disease Models, Animal; Enzyme Inhibitors; Hypercholesterolemia; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Research Design; Time Factors; Ventricular Pressure | 2007 |
Effects of L-arginine on cerebral blood flow, microvascular permeability, number of perfused capillaries, and brain water content in the traumatized mouse brain.
Topics: Animals; Arginine; Body Water; Brain Injuries; Capillaries; Capillary Permeability; Cerebral Cortex; Cerebrovascular Circulation; Chromium Radioisotopes; Disease Models, Animal; Edetic Acid; Male; Mice; Mice, Inbred C57BL | 2007 |
Effect of ocular hypertension on retinal nitridergic pathway activity.
Topics: Amino Acid Transport Systems, Basic; Animals; Anterior Chamber; Arginine; Blotting, Western; Citrulline; Cyclic GMP; Disease Models, Animal; Hyaluronic Acid; Intraocular Pressure; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ocular Hypertension; Radioimmunoassay; Rats; Rats, Wistar; Retina; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome.
Topics: Amino Acid Substitution; Animals; Arginine; Cells, Cultured; Disease Models, Animal; DNA-Binding Proteins; Genetic Diseases, Inborn; Glutamine; Humans; Immune Tolerance; Immunologic Deficiency Syndromes; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Mutagenesis, Site-Directed | 2007 |
Antioxidants combined with NO donor enhance systemic inflammation in acute lung injury in rats.
Topics: Animals; Antioxidants; Arginine; Catalase; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Hemorrhage; Inflammation; Intestines; Male; Neutrophil Infiltration; Nitric Oxide Donors; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Distress Syndrome; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2007 |
Nitric oxide regulates expression of sonic hedgehog and hypoxia-inducible factor-1alpha in an experimental model of kidney ischemia-reperfusion.
Topics: Animals; Arginine; Biomarkers; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Hedgehog Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2007 |
A mouse model of Waardenburg syndrome type IV resulting from an ENU-induced mutation in endothelin 3.
Topics: Animals; Arginine; Chromosome Mapping; Disease Models, Animal; Endothelin-3; Ethylnitrosourea; Gene Expression Regulation; Genetic Linkage; Histidine; Humans; Mice; Mutation; Pigmentation; Point Mutation; Waardenburg Syndrome | 2007 |
Nitric oxide and prostaglandin response to group B streptococcal infection in the lung.
Topics: Animals; Arginine; Cell Line; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Gene Expression Regulation; Guanidines; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Pneumonia, Bacterial; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA, Messenger; Streptococcal Infections; Streptococcus agalactiae | 2007 |
Effect of asymmetric dimethylarginine on atherogenesis and erythrocyte deformability in apolipoprotein E deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Arginine; Atherosclerosis; Disease Models, Animal; Erythrocyte Deformability; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats | 2007 |
Delayed 24 hours Nomega-nitro-L-arginine methyl ester injection induces pharmacological cardioprotection against reperfusion injury.
Topics: Adenosine; Animals; Arginine; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitrates; Nitric Oxide Synthase; Nitrites; Perfusion; Rats; Regional Blood Flow; Theophylline; Time Factors; Troponin I; Ventricular Function, Left | 2007 |
Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat.
Topics: Animals; Anticonvulsants; Arginine; Brain; Dentate Gyrus; Disease Models, Animal; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Epilepsy, Complex Partial; Indazoles; Lamotrigine; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Triazines | 2007 |
An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.
Topics: Alleles; Aneuploidy; Animals; Arginine; Cell Transformation, Neoplastic; Centrosome; Disease Models, Animal; Enzyme Activation; Gene Expression Regulation, Neoplastic; Glycine; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Inbred C57BL; Mutation; ras Proteins; Skin Neoplasms; Tumor Suppressor Protein p53 | 2007 |
Nitric oxide mediates the vagal protective effect on ventricular fibrillation via effects on action potential duration restitution in the rabbit heart.
Topics: Action Potentials; Animals; Arginine; Autonomic Nervous System; Cardiac Pacing, Artificial; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Perfusion; Rabbits; Time Factors; Vagus Nerve; Ventricular Fibrillation; Ventricular Function | 2007 |
Therapeutic efficacy of a 177Lu-labeled DOTA conjugated alpha-melanocyte-stimulating hormone peptide in a murine melanoma-bearing mouse model.
Topics: alpha-MSH; Animals; Arginine; Chelating Agents; Disease Models, Animal; Heterocyclic Compounds, 1-Ring; Kidney; Lutetium; Melanoma; Mice; Radiography; Radioisotopes; Survival Analysis | 2007 |
Formation and progression of sub-retinal pigment epithelium deposits in Efemp1 mutation knock-in mice: a model for the early pathogenic course of macular degeneration.
Topics: Animals; Arginine; Bruch Membrane; Disease Models, Animal; Disease Progression; Extracellular Matrix Proteins; Female; Humans; Macular Degeneration; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis, Site-Directed; Optic Nerve; Pigment Epithelium of Eye; Point Mutation; Retina; Time Factors; Tryptophan | 2007 |
The role of nitric oxide in the anticonvulsant effects of pyridoxine on penicillin-induced epileptiform activity in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Enzyme Inhibitors; Epilepsy; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillins; Pyridoxine; Rats; Rats, Wistar; Somatosensory Cortex; Time Factors | 2007 |
Effects of continuous enteral L-arginine in a rat model of the short bowel syndrome.
Topics: Adaptation, Physiological; Animals; Apoptosis; Arginine; Cell Division; Cell Proliferation; Disease Models, Animal; Enteral Nutrition; Enterocytes; Humans; Ileum; Intestinal Mucosa; Jejunum; Male; Organ Size; Random Allocation; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome | 2007 |
Effects of long-term administration of HMG-CoA reductase inhibitor, atorvastatin, on stroke events and local cerebral blood flow in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Arginine; Atorvastatin; Brain; Cerebral Arteries; Cerebrovascular Circulation; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Lipid Metabolism; Male; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Pyrroles; Rats; Rats, Inbred SHR; Stroke; Survival Rate; Time; Time Factors; Treatment Outcome | 2007 |
Coronary microvascular dysfunction in the setting of chronic ischemia is independent of arginase activity.
Topics: Animals; Arginase; Arginine; Blotting, Western; Chronic Disease; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Fluorescent Antibody Technique; Linear Models; Microcirculation; Myocardial Ischemia; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Swine; Swine, Miniature; Time Factors; Vasodilation; Vasodilator Agents | 2008 |
[Effect of L-Arginine on intestinal mucosal injury of rats with severe abdominal infection].
Topics: Abdominal Cavity; Animals; Arginine; Disease Models, Animal; Female; Infections; Intestinal Mucosa; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Random Allocation; Rats; Rats, Wistar | 2007 |
Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acids; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Myristic Acid; Rats; Rats, Inbred Strains; Reference Values; Soybean Oil | 2007 |
Comparison of the effect of simvastatin, spironolactone and L-arginine on endothelial function of aorta in hereditary hypertriglyceridemic rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Male; Mineralocorticoid Receptor Antagonists; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norepinephrine; Rats; Rats, Wistar; Simvastatin; Spironolactone; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Ghrelin inhibits sympathetic nervous activity in sepsis.
Topics: Animals; Arginine; Disease Models, Animal; Ghrelin; Injections, Intravenous; Injections, Intraventricular; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Ghrelin; Receptors, Neuropeptide Y; Sepsis; Signal Transduction; Substance P; Sympathetic Nervous System; Tumor Necrosis Factor-alpha | 2007 |
Intracarotid L-arginine reverses motor evoked potential changes in experimental cerebral vasospasm.
Topics: Animals; Arginine; Carotid Arteries; Disease Models, Animal; Evoked Potentials, Motor; Female; Injections, Intra-Arterial; Male; Nitric Oxide; Rabbits; Reaction Time; Subarachnoid Hemorrhage; Transcranial Magnetic Stimulation; Vasospasm, Intracranial | 2007 |
Interaction between murine spf-ash mutation and genetic background yields different metabolic phenotypes.
Topics: Alanine; Ammonia; Animals; Arginine; Citrulline; Disease Models, Animal; Female; Glycine; Injections, Intravenous; Intestinal Mucosa; Liver; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mice, Mutant Strains; Models, Biological; Mutation; Nitric Oxide; Ornithine; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Phenotype; Phenylalanine; Urea | 2007 |
Oxidative stress attenuates NO-induced modulation of sympathetic neurotransmission in the mesenteric arterial bed of spontaneously hypertensive rats.
Topics: Acetylcysteine; Animals; Antioxidants; Arginine; Blood Pressure; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Neuropeptide Y; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Splanchnic Circulation; Superoxides; Sympathetic Nervous System | 2008 |
Acute exposure to a moderate strength static magnetic field reduces edema formation in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Calcium; Calcium Channel Agonists; Calcium Channels, L-Type; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Radiation; Edema; Electromagnetic Fields; Histamine; Inflammation; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Severity of Illness Index; Signal Transduction; Time Factors | 2008 |
The effects of arginine and selective inducible nitric oxide synthase inhibitor on pathophysiology of sepsis in a CLP model.
Topics: Animals; Arginine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Guanidines; Heme Oxygenase-1; Male; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Sepsis | 2008 |
Nitric oxide synthesis inhibition attenuates iron-induced neurotoxicity: a stereological study.
Topics: Animals; Arginine; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Hippocampus; Iron; Male; Neurons; Neurotoxicity Syndromes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Stereotaxic Techniques | 2008 |
[L-arginine reduces intestinal epithelial cell apoptosis in rats with severe abdominal infection].
Topics: Abdominal Cavity; Animals; Apoptosis; Arginine; Cecum; Disease Models, Animal; Epithelial Cells; Infections; Intestinal Mucosa; Rats; Rats, Wistar | 2007 |
HO-1 overexpression attenuates endotoxin effects on CAT-2 isozymes expression.
Topics: Animals; Arginine; Cationic Amino Acid Transporter 2; Disease Models, Animal; Endotoxins; Enzyme Inhibitors; Heme Oxygenase-1; Hemin; Isoenzymes; Kidney; Lipopolysaccharides; Liver; Lung; Male; Metalloporphyrins; Nitric Oxide; Nitric Oxide Synthase Type II; Protoporphyrins; Rats; Rats, Sprague-Dawley; Sepsis | 2008 |
Role of nitric oxide deficiency in the development of hypertension in hydronephrotic animals.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Diuresis; Enzyme Inhibitors; Hydronephrosis; Hypertension; Indazoles; Kidney; Kidney Cortex; Kidney Tubules, Proximal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Sodium Chloride, Dietary; Ureteral Obstruction | 2008 |
Effects of dipeptidyl peptidase iv inhibition on arterial blood pressure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Captopril; Chlorisondamine; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Ganglionic Blockers; Hydralazine; Hypertension; Pentanoic Acids; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Thiazolidines; Vasodilator Agents | 2008 |
Synergistic myoprotection of L-arginine and adenosine in a canine model of global myocardial ischaemic reperfusion injury.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Cardiotonic Agents; Disease Models, Animal; Dogs; Drug Synergism; Energy Metabolism; Female; Heart Arrest, Induced; Male; Myocardial Reperfusion Injury; Myocardium; Peroxidase | 2007 |
Effects of endogenous nitric oxide induced by 5-fluorouracil and L-Arg on liver carcinoma in nude mice.
Topics: Animals; Antimetabolites; Apoptosis; Arginine; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p16; Disease Models, Animal; Fluorouracil; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Xenograft Model Antitumor Assays | 2007 |
Role of the NO/cGMP/K(ATP) pathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats.
Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Diazoxide; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Glyburide; Guanylate Cyclase; Hemoglobins; KATP Channels; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Potassium Channel Blockers; Purines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones | 2008 |
Sildenafil reduces alcohol-induced gastric damage: just say 'NO'.
Topics: Animals; Arginine; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Disease Models, Animal; Ethanol; Gastric Mucosa; Glutathione; Guanylate Cyclase; Hemoglobins; KATP Channels; Nitric Oxide; Nitric Oxide Synthase; Peptic Ulcer Hemorrhage; Phosphodiesterase 5 Inhibitors; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Signal Transduction; Sildenafil Citrate; Stomach Ulcer; Sulfones | 2008 |
The effect of Nomega-nitro-L-arginine methyl ester and L-arginine on lung injury induced by abdominal aortic occlusion-reperfusion.
Topics: Animals; Aorta, Abdominal; Arginine; Arterial Occlusive Diseases; Biomarkers; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Lung; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Spectrophotometry; Treatment Outcome; Vascular Endothelial Growth Factor A | 2008 |
Mutant p53(R270H) gain of function phenotype in a mouse model for oncogene-induced mammary carcinogenesis.
Topics: Adenocarcinoma; Animals; Antigens, Polyomavirus Transforming; Arginine; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Female; Genes, p53; Histidine; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Transgenic; Mutation, Missense; Oncogenes; Phenotype; Point Mutation; Tumor Suppressor Protein p53 | 2008 |
Interleukin-4-transgenic hu-PBL-SCID mice: a model for the screening of antiviral drugs and immunotherapeutic agents against X4 HIV-1 viruses.
Topics: Animals; Arginine; Disease Models, Animal; HIV Infections; HIV-1; Humans; Interleukin-4; Mice; Mice, SCID; Mice, Transgenic; Pyridines; Receptors, CXCR4 | 2008 |
Protective effect of nitric oxide synthase inhibition or antioxidants on brain oxidative damage caused by intracerebroventricular arginine administration.
Topics: alpha-Tocopherol; Amidines; Analysis of Variance; Animals; Antioxidants; Arginine; Ascorbic Acid; Brain Injuries; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Hippocampus; Injections, Intraventricular; Male; NG-Nitroarginine Methyl Ester; Oxidative Stress; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Thiobarbituric Acid Reactive Substances | 2008 |
C3a receptor modulation of granulocyte infiltration after murine focal cerebral ischemia is reperfusion dependent.
Topics: Anaphylatoxins; Animals; Arginine; Benzhydryl Compounds; Brain; Brain Ischemia; Complement C3a; Disease Models, Animal; Flow Cytometry; Granulocytes; Infarction, Middle Cerebral Artery; Intercellular Adhesion Molecule-1; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Receptors, Complement; Reperfusion Injury | 2008 |
Oral delivery of L-arginine stimulates prostaglandin-dependent secretory diarrhea in Cryptosporidium parvum-infected neonatal piglets.
Topics: Alanine; Analysis of Variance; Animals; Animals, Newborn; Arginine; Atrophy; Chlorides; Cryptosporidiosis; Cryptosporidium parvum; Cyclooxygenase Inhibitors; Diarrhea; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Ileum; Indomethacin; Intestinal Mucosa; Nitric Oxide; Oocysts; Parasite Egg Count; Prostaglandins; Random Allocation; Severity of Illness Index; Swine | 2008 |
A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis.
Topics: Acrocephalosyndactylia; Animals; Arginine; Biomimetics; Cells, Cultured; Chondrogenesis; Disease Models, Animal; Humans; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Ossification, Heterotopic; Osteogenesis; Proline; Receptor, Fibroblast Growth Factor, Type 2; Skeleton | 2008 |
Cytoprotective role of nitric oxide associated with Hsp70 expression in neonatal obstructive nephropathy.
Topics: Animals; Animals, Newborn; Apoptosis; Arginine; bcl-2-Associated X Protein; Body Weight; Caspase 3; Cytoprotection; Disease Models, Animal; Female; HSP70 Heat-Shock Proteins; Immunoprecipitation; Kidney; Kidney Diseases; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Organ Size; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Ureteral Obstruction | 2008 |
Glycemic control modulates arginine and asymmetrical-dimethylarginine levels during critical illness by preserving dimethylarginine-dimethylaminohydrolase activity.
Topics: Amidohydrolases; Animals; Arginine; Blood Glucose; Body Weight; Creatinine; Critical Illness; Disease Models, Animal; Humans; Insulin; Rabbits | 2008 |
Kidney damage after renal ablation is worsened in endothelial nitric oxide synthase -/- mice and improved by combined administration of L-arginine and antioxidants.
Topics: Animals; Antioxidants; Arginine; Blood Pressure; Disease Models, Animal; Drug Combinations; Kidney; Kidney Failure, Chronic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephrectomy; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Proteinuria; Superoxides; Time Factors; Tyrosine | 2008 |
Brief femoral artery ischaemia provides protection against myocardial ischaemia-reperfusion injury in rats: the possible mechanisms.
Topics: Animals; Arginine; Blood Pressure; Creatine Kinase, MB Form; Diazoxide; Disease Models, Animal; Femoral Artery; Heart Rate; Hindlimb; Ischemia; Ischemic Preconditioning, Myocardial; KATP Channels; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Vasodilator Agents | 2008 |
Inhibition of inducible nitric oxide synthase activity prevents liver recovery in rat thioacetamide-induced fibrosis reversal.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Liver; Liver Cirrhosis; Liver Regeneration; Male; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Thioacetamide | 2008 |
Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease.
Topics: Animals; Arginine; Asparagine; Disease Models, Animal; Female; Glutamine; Huntington Disease; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Neurologic Mutants; Mice, Transgenic; Neuroprotective Agents; Nipecotic Acids; PC12 Cells; Rats; Tiagabine | 2008 |
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.
Topics: Amiloride; Amino Acids, Cyclic; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Synergism; Homeostasis; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Ketoglutarate Dehydrogenase Complex; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Sodium-Calcium Exchanger | 2008 |
[Effect of L-arginine, vitamins C and E, and omega-3 acids (DHA, EPA) on oxidative stress and endothelial dysfunction in the mouse model of renal insufficiency].
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Endothelium; Male; Oxidative Stress; Rats; Renal Insufficiency; Vitamin E | 2007 |
Effects of long-term losartan and L-arginine treatment on haemodynamics, glomerular filtration, and SOD activity in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Abdominal; Arginine; Blood Pressure; Carotid Arteries; Disease Models, Animal; Drug Therapy, Combination; Glomerular Filtration Rate; Hemodynamics; Hypertension; Kidney; Losartan; Male; Nitric Oxide Donors; Rats; Rats, Inbred SHR; Regional Blood Flow; Renal Artery; Renal Circulation; Superoxide Dismutase; Time Factors; Urea; Vascular Resistance | 2008 |
Hypertonic resuscitation improves neuronal and behavioral outcomes after traumatic brain injury plus hemorrhage.
Topics: Animals; Arginine; Behavior; Brain Injuries; Cerebral Hemorrhage; Disease Models, Animal; Hypertonic Solutions; Male; Rats; Rats, Sprague-Dawley; Resuscitation; Saline Solution, Hypertonic; Treatment Outcome | 2008 |
Effects of glucocorticoid agonist and antagonist on the pathogenesis of L-arginine-induced acute pancreatitis in rat.
Topics: Acute Disease; Amylases; Animals; Arginine; Disease Models, Animal; Glucocorticoids; Inflammation; Interleukin-6; L Cells; Macrophage Migration-Inhibitory Factors; Male; Methylprednisolone; Mice; Mifepristone; Pancreatitis; Rats; Rats, Wistar | 2008 |
Chronic L-arginine administration increases oxidative and nitrosative stress in rat hyperoxaluric kidneys and excessive crystal deposition.
Topics: Animals; Arginine; Calcium Oxalate; Crystallization; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydroxyproline; Hyperoxaluria; Kidney; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides | 2008 |
Arginine therapy of transgenic-knockout sickle mice improves microvascular function by reducing non-nitric oxide vasodilators, hemolysis, and oxidative stress.
Topics: Acetylcholine; Anemia, Sickle Cell; Animals; Arginine; Citrulline; Cyclooxygenase 2; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Globins; Heme Oxygenase-1; Hemodynamics; Hemoglobins; Hemolysis; Humans; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Oxidative Stress; Tyrosine; Vasodilator Agents | 2008 |
The homocysteine paradox.
Topics: Animals; Arginine; Cardiovascular Diseases; Cystatin C; Cystatins; Disease Models, Animal; Folic Acid; Glomerular Filtration Rate; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Diseases; Risk Factors; Vitamin B 12; Vitamin B 6 | 2008 |
The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology.
Topics: Anemia, Sickle Cell; Animals; Arginine; Disease Models, Animal; Hemodynamics; Hemoglobins; Hemolysis; Humans; Microcirculation; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Tyrosine; Vasodilator Agents | 2008 |
Islet secretion in a new experimental model for non-insulin-dependent diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Male; Pregnancy; Rats; Somatostatin; Theophylline; Tolbutamide | 1981 |
Hyperargininemia: the rat as a model for the human disease and the comparative response to enzyme replacement therapy with free arginase and arginase-loaded erythrocytes in vivo.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Arginase; Arginine; Disease Models, Animal; Erythrocytes; Hemolysis; Humans; Hyperargininemia; Kinetics; Rats; Rats, Inbred Strains | 1984 |
Interactions of aspirin and other potential etiologic factors in an animal model of Reye syndrome.
Topics: Ammonia; Animals; Arginine; Aspartate Aminotransferases; Aspirin; Diet; Disease Models, Animal; Ferrets; Lipid Metabolism; Liver; Orthomyxoviridae Infections; Reye Syndrome; Urea | 1982 |
Spontaneous diabetes mellitus in the New Zealand white rabbit: physiologic characteristics.
Topics: Acetoacetates; Animals; Arginine; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Female; Glucose Tolerance Test; Hydroxybutyrates; Insulin; Ketone Bodies; Male; Rabbits | 1981 |
Serum enzyme alterations in arginine-deficient, influenza-infected ferrets: a potential animal model of Reye's syndrome.
Topics: Ammonia; Animals; Arginine; Aspartate Aminotransferases; Disease Models, Animal; Ferrets; Humans; Influenza, Human; Male; Ornithine Carbamoyltransferase; Reye Syndrome | 1982 |
BAEE esterase (kallikrein-like) activity in parotid saliva of normal rats and rats with various forms of experimental hypertension (genuine, renovascular and DOCA salt hypertension).
Topics: Animals; Arginine; Carboxylic Ester Hydrolases; Desoxycorticosterone; Disease Models, Animal; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Parotid Gland; Rats; Saliva | 1980 |
A new approach for the pathogenesis of human African trypanosomiasis.
Topics: Animals; Arginine; Brain; CD8-Positive T-Lymphocytes; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Sensory; Ganglia, Spinal; Growth Substances; Hot Temperature; Humans; Hyperalgesia; Injections, Spinal; Interferon-gamma; Mice; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nociceptors; Rats; Trypanosoma brucei brucei; Trypanosomiasis, African | 1994 |
The role of nitric oxide in enteropathy.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Graft vs Host Reaction; Hyperplasia; Hypertrophy; Intestinal Diseases; Intestinal Mucosa; Mice; Nitric Acid; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Spleen; Transplantation, Homologous | 1995 |
Role of nitric oxide synthesis in salt-sensitive hypertension in Dahl/Rapp rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Citrulline; Cyclic GMP; Dexamethasone; Disease Models, Animal; Homoarginine; Hypertension; Insulin; Male; Nitrates; Nitric Oxide; Ornithine; Rats; Rats, Inbred Strains | 1993 |
Intrahippocampal administration of the NO synthase inhibitor L-NAME prevents working memory deficits in rats exposed to transient cerebral ischemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Disease Models, Animal; Hippocampus; Injections; Ischemic Attack, Transient; Male; Memory Disorders; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 1994 |
Endogenous nitric oxide enhances prostaglandin production in a model of renal inflammation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cholic Acids; Dinoprostone; Disease Models, Animal; Hydronephrosis; In Vitro Techniques; Indomethacin; Kidney; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Prostaglandin-Endoperoxide Synthases; Rabbits; Ureter | 1994 |
N-monomethyl arginine, an inhibitor of nitric oxide synthase, suppresses the development of adjuvant arthritis in rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arthritis, Experimental; Disease Models, Animal; Male; Nitrates; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Rats; Rats, Inbred Lew | 1994 |
Release of nitric oxide during the experimental infection with Trypanosoma cruzi.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Base Sequence; Chagas Disease; Disease Models, Animal; DNA Primers; Female; Interferon-gamma; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Peritoneal Cavity; RNA, Messenger; Spleen; Trypanosoma cruzi; Virulence | 1994 |
The role of nitric oxide synthase in endotoxin-induced uveitis: effects of NG-nitro L-arginine.
Topics: Amino Acid Oxidoreductases; Animals; Anterior Eye Segment; Aqueous Humor; Arginine; Bacterial Toxins; Disease Models, Animal; Endotoxins; Enterotoxins; Enzyme Induction; Eye Proteins; Leukocyte Count; Male; Neutrophils; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Inbred Lew; Salmonella; Uveitis, Anterior | 1994 |
Activity of the L-arginine/nitric oxide pathway and endothelin-1 in experimental heart failure.
Topics: Acetylcholine; Animals; Aorta; Arginine; Body Weight; Cricetinae; Disease Models, Animal; Endothelins; Endothelium, Vascular; Heart Failure; In Vitro Techniques; Male; Mesenteric Arteries; Mesocricetus; Muscle Relaxation; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Organ Size; Vascular Resistance | 1994 |
Modulation of hemodynamics and organ blood flow by nitric oxide synthase inhibition is not altered in normotensive, septic rats.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cecum; Disease Models, Animal; Dose-Response Relationship, Drug; Hemodynamics; Intestine, Small; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sepsis; Wakefulness | 1994 |
Spinal mediators of hyperalgesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arginine; Calcium; Cycloleucine; Disease Models, Animal; Excitatory Amino Acids; Hot Temperature; Hyperalgesia; Male; N-Methylaspartate; Neuronal Plasticity; Neurons, Afferent; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stress, Mechanical | 1994 |
[Study on roles of L-arginine to nitric oxide pathway for the cardiovascular control: assessment with a new model of hypertension produced by the chronic administration of nitric oxide synthase inhibitor].
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Division; Chronic Disease; Disease Models, Animal; Hemodynamics; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Wistar; Sympathetic Nervous System | 1994 |
The effects of nitric oxide inhibition on regional hemodynamics during hyperdynamic endotoxemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacteremia; Blood Gas Analysis; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Escherichia coli Infections; Hemodynamics; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Sepsis | 1994 |
NG-Nitro-L-arginine protects against ischaemia-induced increases in nitric oxide and hippocampal neuro-degeneration in the gerbil.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Brain Ischemia; Brain Stem; Carotid Arteries; Cell Death; Cerebellum; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Gerbillinae; Hippocampus; Male; Microscopy, Fluorescence; Motor Activity; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Paraffin Embedding; Reperfusion Injury | 1994 |
Effect of inhibition of nitric oxide synthase in acute renal failure due to endotoxin shock in dogs.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Dogs; Hemodynamics; Kidney; Lipopolysaccharides; Liver; Nitric Oxide Synthase; omega-N-Methylarginine; Shock, Septic | 1994 |
First place winner of the Conrad Jobst Award in the gold medal paper competition. Nitric oxide synthase inhibitors N-monomethylarginine and aminoguanidine prevent the progressive and severe hypotension associated with a rat model of pancreatitis.
Topics: Amylases; Animals; Arginine; Blood Pressure; Calcium; Clinical Protocols; Disease Models, Animal; Drug Evaluation, Preclinical; Fluid Therapy; Guanidines; Humans; Hypotension; Immunohistochemistry; Male; Multiple Organ Failure; Nitric Oxide; omega-N-Methylarginine; Pancreatitis; Premedication; Rats; Rats, Sprague-Dawley; Resuscitation; Severity of Illness Index | 1995 |
Role of L-arginine-derived NO in ischemic acute renal failure in the rat.
Topics: Acute Kidney Injury; Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Female; Glomerular Filtration Rate; Ischemia; Kidney; Natriuresis; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Urodynamics | 1994 |
Alterations of ex vivo vascular reactivity in intraperitoneal sepsis.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Temperature; Cecum; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Sepsis; Vascular Resistance; Vasoconstrictor Agents; Vasodilator Agents | 1994 |
Cyclic nucleotides and vasoactive intestinal peptide production in a rabbit model of Escherichia coli septicemia.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bacteremia; Blood Pressure; Cyclic AMP; Cyclic GMP; Disease Models, Animal; Escherichia coli Infections; Heart Rate; Lactates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rabbits; Reference Values; Vasoactive Intestinal Peptide | 1995 |
Use of L-arginine in the treatment of experimental necrotizing enterocolitis.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Caseins; Disease Models, Animal; Enterocolitis, Pseudomembranous; Gastrointestinal Motility; Infusions, Intravenous; Intestinal Mucosa; Nitric Oxide Synthase; Swine | 1995 |
Increased nitric oxide production in endotoxin-induced uveitis. Reduction of uveitis by an inhibitor of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Aqueous Humor; Arginine; Base Sequence; Disease Models, Animal; DNA Primers; Endotoxins; Male; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Polymerase Chain Reaction; Rats; Rats, Inbred BN; Rats, Inbred Lew; RNA, Messenger; Uveitis; Vitreous Body | 1995 |
Dose-dependent anticonvulsant and proconvulsant effects of nitric oxide synthase inhibitors on seizure threshold in a cortical stimulation model in rats.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electrodes, Implanted; Epilepsy; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Valproic Acid | 1995 |
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Guanidines; Heart Rate; Hypotension; Lipopolysaccharides; Male; Mice; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Rats; Rats, Wistar; Shock, Septic; Time Factors | 1995 |
Assessment of renal dopaminergic system activity in the nitric oxide-deprived hypertensive rat model.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Disease Models, Animal; Dopamine; Drinking; Heart Rate; Hypertension; Kidney; Kinetics; Levodopa; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Urination | 1995 |
The role of inducible nitric oxide synthase in vascular hyporeactivity of endotoxin-treated and portal hypertensive rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Disease Models, Animal; Endotoxins; Enzyme Induction; Escherichia coli; Guanidines; Hypertension, Portal; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vascular Resistance | 1995 |
Effects of nitric oxide synthase inhibition on regional blood flow in a porcine model of endotoxic shock.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Cardiac Output; Carotid Arteries; Disease Models, Animal; Escherichia coli Infections; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Regional Blood Flow; Renal Circulation; Resuscitation; Shock, Septic; Splanchnic Circulation; Swine | 1995 |
Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity.
Topics: Animals; Arginine; Calmodulin-Binding Proteins; Capsaicin; Colitis; Disease Models, Animal; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 1995 |
Impairment of endothelium-dependent vasorelaxation in chronic two-kidney, one clip hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Atrial Natriuretic Factor; Chronic Disease; Disease Models, Animal; Hypertension, Renal; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Rats; Rats, Sprague-Dawley; Vasodilation | 1995 |
Structure and function of the rat basilar artery during chronic nitric oxide synthase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Basilar Artery; Blood Pressure; Cerebrovascular Circulation; Disease Models, Animal; Endothelins; Enzyme Inhibitors; Hypertension; Image Processing, Computer-Assisted; Indoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Serotonin; Vasodilator Agents; Verapamil; Video Recording | 1995 |
Effect of methylguanidine on rat blood pressure: role of endothelial nitric oxide synthase.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Ganglionic Blockers; Hexamethonium; Hypertension; Injections, Intravenous; Male; Methylguanidine; Nitric Oxide Synthase; Rats; Rats, Wistar; Stereoisomerism; Uremia | 1995 |
Polydeoxyribonucleotides and nitric oxide release from guinea-pig hearts during ischaemia and reperfusion.
Topics: Acetylcholine; Animals; Arginine; Arrhythmias, Cardiac; Chemical Fractionation; Coronary Circulation; Disease Models, Animal; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Guinea Pigs; Male; Molecular Weight; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Polydeoxyribonucleotides | 1995 |
Protamine-induced pulmonary venoconstriction in heparinized pigs.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Central Venous Pressure; Disease Models, Animal; Female; Heparin; Hypertension, Pulmonary; Male; Nitric Oxide; Nitroarginine; Protamines; Pulmonary Artery; Pulmonary Veins; Pulmonary Wedge Pressure; Swine; Vascular Resistance; Vasoconstrictor Agents | 1995 |
Reduced intestinal absorption of arginine during sepsis.
Topics: Animals; Arginine; Cecum; Disease Models, Animal; Escherichia coli; Intestinal Absorption; Jejunum; Ligation; Lipopolysaccharides; Male; Punctures; Rats; Rats, Sprague-Dawley; Sepsis; Time Factors | 1995 |
Effect of inhibiting NO synthesis on hippocampal extracellular glutamate concentration in seizures induced by kainic acid.
Topics: Animals; Arginine; Blood Glucose; Disease Models, Animal; Electrophysiology; Glutamic Acid; Hippocampus; Kainic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Seizures; Time Factors | 1995 |
Role of nitric oxide in porcine liver circulation under normal and endotoxemic conditions.
Topics: Animals; Arginine; Blood Flow Velocity; Disease Models, Animal; Endotoxins; Hepatic Artery; Liver Circulation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Portal Vein; Shock, Septic; Swine | 1995 |
Discordant effects of dietary L-arginine on vascular structure and reactivity in hypercholesterolemic rabbits.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Abdominal; Arginine; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hypercholesterolemia; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Norepinephrine; Rabbits; Random Allocation; Stereoisomerism | 1995 |
The role of endothelin and nitric oxide in modulation of normal and spastic cerebral vascular tone in the dog.
Topics: Amino Acid Sequence; Animals; Arginine; Basilar Artery; Cisterna Magna; Disease Models, Animal; Dogs; Endothelins; Female; Immunohistochemistry; Ischemic Attack, Transient; Male; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptides, Cyclic; Radiography; Subarachnoid Hemorrhage | 1995 |
Electrophysiological and pharmacological responses of chronically denervated lower esophageal sphincter of the opossum.
Topics: Analysis of Variance; Animals; Arginine; Atropine; Benzalkonium Compounds; Cholinergic Fibers; Denervation; Disease Models, Animal; Electric Stimulation; Electrophysiology; Esophageal Achalasia; Esophagogastric Junction; Female; In Vitro Techniques; Male; Manometry; Muscle Contraction; Muscle Relaxation; Myenteric Plexus; Neurons; Nitric Oxide; Opossums; Pressure; Tetrodotoxin | 1995 |
Nitric oxide production in experimental alcoholic liver disease in the rat: role in protection from injury.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Liver; Liver Diseases, Alcoholic; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar | 1995 |
Role of endothelium-derived relaxing factor in the maintenance of renal blood flow in a rodent model of chronic hydronephrosis.
Topics: Acetylcholine; Animals; Arginine; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Hemodynamics; Hydronephrosis; Male; Microcirculation; Microscopy, Video; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction | 1995 |
Amelioration of chronic ileitis by nitric oxide synthase inhibition.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Chronic Disease; Disease Models, Animal; Guinea Pigs; Ileitis; Ileum; Intestinal Mucosa; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Organ Size; Peroxidase; Therapeutic Irrigation; Trinitrobenzenesulfonic Acid | 1993 |
Control of renin gene expression in 2 kidney-1 clip rats.
Topics: Animals; Arginine; Denervation; Disease Models, Animal; Furosemide; Gene Expression Regulation; Hypertension, Renovascular; Kidney; Male; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Antagonists; Ramipril; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger | 1994 |
Endothelinb receptor agonists produce pulmonary vasodilation in intact newborn lambs with pulmonary hypertension.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Arginine; Blood Pressure; Disease Models, Animal; Endothelins; Endothelium, Vascular; Glyburide; Hypertension, Pulmonary; Injections, Intra-Arterial; Nitroarginine; Peptide Fragments; Prostaglandin Endoperoxides, Synthetic; Pulmonary Artery; Pulmonary Circulation; Regional Blood Flow; Sheep; Thromboxane A2; Vascular Resistance; Vasoconstrictor Agents; Vasodilation | 1995 |
Renal hypertensive angiopathy. Comparison between chronic NO suppression and DOCA-salt intoxication.
Topics: Animals; Aorta; Arginine; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclic GMP; Desoxycorticosterone; Disease Models, Animal; Hypertension, Renal; Hypertrophy, Left Ventricular; Male; Mortality; NG-Nitroarginine Methyl Ester; Proteinuria; Rats; Rats, Wistar; Renin-Angiotensin System | 1995 |
Nitric oxide mediates neuropathic pain behavior in peripherally denervated rats.
Topics: Animals; Arginine; Behavior, Animal; Cyclic AMP; Denervation; Disease Models, Animal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Peripheral Nerves; Phantom Limb; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Stereoisomerism; Synaptic Transmission; Time Factors | 1995 |
Endotoxin-stimulated nitric oxide production increases injury and reduces rat liver chemiluminescence during reperfusion.
Topics: Animals; Arginine; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Lipopolysaccharides; Liver Diseases; Luminescent Measurements; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase | 1995 |
Targets of nitric oxide in a mouse model of liver inflammation by Corynebacterium parvum.
Topics: Animals; Arginine; Blood; Blotting, Western; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Inflammation; Liver; Liver Diseases; Male; Mice; Nitric Oxide; omega-N-Methylarginine; Propionibacterium acnes | 1995 |
Enhancement of thrombolytic efficacy of tissue-type plasminogen activator by adjuvants in the guinea pig thrombosis model.
Topics: Adjuvants, Pharmaceutic; Animals; Antithrombins; Arginine; Biphenyl Compounds; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Femoral Artery; Fibrinolytic Agents; Guinea Pigs; Heptanoic Acids; Indoles; Leukotriene Antagonists; Male; Microscopy, Electron, Scanning; Neutrophils; Pipecolic Acids; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Recombinant Proteins; Sulfonamides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1994 |
Modulation of granuloma formation by endogenous nitric oxide.
Topics: Animals; Arginine; Carrageenan; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Implants; Granuloma; Inflammation; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrites; Polymers; Prostheses and Implants; Rats; Rats, Wistar; Stereoisomerism | 1994 |
Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis.
Topics: Animals; Arginine; Disease Models, Animal; Glomerulonephritis; Male; Neutrophils; Nitric Oxide; omega-N-Methylarginine; Proteinuria; Rats; Rats, Wistar; Renal Circulation | 1994 |
Effect of inhibition of nitric oxide release on the diaphragmatic oxygen delivery-consumption relationship.
Topics: Animals; Arginine; Diaphragm; Disease Models, Animal; Dogs; Infusions, Intra-Arterial; Muscle Tonus; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Oxygen Consumption; Vascular Resistance | 1994 |
The pulmonary effect of nitric oxide synthase inhibition following endotoxemia in a swine model.
Topics: Administration, Inhalation; Animals; Arginine; Bacteremia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli Infections; Female; Hypertension, Pulmonary; Hypoxia; Lung Volume Measurements; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Edema; Pulmonary Wedge Pressure; Random Allocation; Swine | 1994 |
Nitric oxide inhibition normalizes splenocyte interleukin-10 synthesis in murine thermal injury.
Topics: Alcoholism; Animals; Arginine; Burns; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Interferon-gamma; Interleukin-10; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitrites; omega-N-Methylarginine; Random Allocation; Spleen | 1994 |
Normalization of hair growth in sparse fur-abnormal skin and hair (SPF-ASH) mice by introduction of the rat ornithine transcarbamylase (OTC) gene.
Topics: Animals; Arginine; Citrulline; Crosses, Genetic; Disease Models, Animal; Female; Genetic Linkage; Hair; Intestine, Small; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Ornithine Carbamoyltransferase; Ornithine Carbamoyltransferase Deficiency Disease; Orotic Acid; Phenotype; Rats; Skin Abnormalities; X Chromosome | 1994 |
Experimental microsporidiosis in immunocompetent and immunodeficient mice and monkeys.
Topics: Animals; Antibodies, Protozoan; Arginine; Cytokines; Disease Models, Animal; Encephalitozoon; Encephalitozoonosis; Female; Immunocompetence; Interferon-gamma; Lipopolysaccharides; Macaca mulatta; Macrophages, Peritoneal; Mice; Mice, Inbred Strains; Microsporidiosis; Nitric Oxide; Nosema; omega-N-Methylarginine; Opportunistic Infections; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus | 1994 |
L-arginine reverses the impairment of nitric oxide-dependent collateral perfusion in dietary-induced hypercholesterolaemia in the rabbit.
Topics: Acetylcholine; Animals; Arginine; Arterial Occlusive Diseases; Collateral Circulation; Disease Models, Animal; Endothelium, Vascular; Hypercholesterolemia; Muscle Relaxation; Muscle, Smooth, Vascular; Perfusion; Rabbits; Regional Blood Flow | 1994 |
The inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescence.
Topics: Administration, Inhalation; Animals; Arginine; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Inflammation; Luminescent Measurements; Lung; Lung Diseases; Male; NG-Nitroarginine Methyl Ester; Nitrates; Rats; Rats, Inbred F344; Silicon Dioxide; Superoxide Dismutase | 1994 |
Inhibitor of nitric oxide synthesis reduces hypoxic-ischemic brain damage in the neonatal rat.
Topics: Animals; Animals, Newborn; Arginine; Brain Ischemia; Disease Models, Animal; Female; Hypoxia, Brain; Male; Nitric Oxide; Nitroarginine; Rats; Rats, Wistar; Time Factors | 1994 |
The role of nitric oxide in uveitis.
Topics: Animals; Aqueous Humor; Arginine; Bacterial Toxins; Disease Models, Animal; Endotoxins; Eye Proteins; Leukocyte Count; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred Lew; Uveitis, Anterior | 1994 |
Effect of nitric oxide and prostaglandins on renal function in insulin-resistant hypertensive dogs.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Diuresis; Dogs; Fructose; Glomerular Filtration Rate; Hypertension; Insulin Resistance; Kidney; Male; Meclofenamic Acid; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Renal Circulation | 1993 |
Effects of inhaled nitric oxide on pulmonary hemodynamics and gas exchange in an ovine model of ARDS.
Topics: Administration, Inhalation; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Hemodynamics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen Consumption; Pulmonary Circulation; Pulmonary Gas Exchange; Respiratory Distress Syndrome; Respiratory Mechanics; Sheep; Therapeutic Irrigation | 1994 |
Selective impairment of the cytoplasmic Ca2+ response to glucose in pancreatic beta cells of streptozocin-induced non-insulin-dependent diabetic rats.
Topics: Animals; Animals, Newborn; Arginine; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Wistar; Streptozocin; Time Factors | 1993 |
Endogenous nitric oxide protects against platelet-activating factor-induced bowel injury in the rat.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Enterocolitis, Pseudomembranous; Hematocrit; Intestines; Male; Mesenteric Artery, Superior; Necrosis; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxidase; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Superoxides | 1993 |
L-arginine administration normalizes pressure natriuresis in hypertensive Dahl rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Disease Models, Animal; Glomerular Filtration Rate; Hypertension; Inulin; Kidney; Male; Natriuresis; Rats; Rats, Inbred Strains; Renal Circulation; Sodium; Sodium, Dietary | 1993 |
Pancreatic atrophy: a new model using serial intra-peritoneal injections of L-arginine.
Topics: Animals; Arginine; Atrophy; Chronic Disease; Disease Models, Animal; Injections, Intraperitoneal; Male; Pancreas; Pancreatitis; Rats; Rats, Sprague-Dawley | 1993 |
NG-methyl-L-arginine restores arterial pressure in hemorrhaged rats.
Topics: Animals; Arginine; Arteries; Blood Pressure; Disease Models, Animal; Hypotension; Male; omega-N-Methylarginine; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Vascular Resistance | 1993 |
Vascular endothelium as a target and effector organ.
Topics: Acute Disease; Animals; Arginine; Cerebrovascular Circulation; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Homeostasis; Hypoxia; Infusions, Intravenous; Nitric Oxide; Nitroarginine; Oxygen Consumption; Pulmonary Circulation; Streptococcal Infections; Streptococcus agalactiae; Swine | 1993 |
Hypoxia causes an abnormal contractile response in the atherosclerotic rabbit aorta. Implication of reduced nitric oxide and cGMP production.
Topics: Animals; Aorta; Arginine; Arteriosclerosis; Calcium; Cell Hypoxia; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Male; Methylene Blue; Nitric Oxide; Nitroarginine; Rabbits; Serotonin; Vasoconstriction | 1993 |
Atrial natriuretic factor influences in vivo plasma, lung and aortic wall cGMP concentrations differently.
Topics: Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Cyclic GMP; Disease Models, Animal; Infusions, Intravenous; Lung; Male; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Renin | 1993 |
Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATPase in glucose-desensitized rat islets.
Topics: Animals; Arginine; Biological Transport; Carbachol; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Hyperglycemia; Inositol; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Potassium-Exchanging ATPase; Time Factors; Tritium | 1993 |
Subarachnoid hemorrhage and endothelial L-arginine pathway in small brain stem arteries in dogs.
Topics: Animals; Arginine; Arterioles; Bradykinin; Brain Stem; Calcimycin; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Male; NG-Nitroarginine Methyl Ester; Subarachnoid Hemorrhage; Vasodilation; Vasopressins | 1993 |
Action of carbon dioxide on hypoxic pulmonary vasoconstriction in the rat lung: evidence against specific endothelium-derived relaxing factor-mediated vasodilation.
Topics: Angiotensin II; Animals; Arginine; Blood Gas Analysis; Carbon Dioxide; Constriction, Pathologic; Disease Models, Animal; Drug Evaluation, Preclinical; Hypercapnia; Hypoxia; Male; Nitric Oxide; omega-N-Methylarginine; Pulmonary Circulation; Pulmonary Wedge Pressure; Random Allocation; Rats; Rats, Wistar; Respiration, Artificial; Vascular Resistance | 1993 |
Role of nitric oxide in the hemodynamic changes of sepsis.
Topics: Acetylcholine; Animals; Arginine; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli Infections; Hemodynamics; Infusions, Intravenous; Injections, Intravenous; Nitric Oxide; Nitroarginine; Random Allocation; Sheep; Shock, Septic | 1993 |
Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant.
Topics: 3T3 Cells; Animals; Arginine; Cell Line; Chronic Disease; Cysteine; Cytoskeleton; Disease Models, Animal; Glycoproteins; Glycosylation; Hepatitis, Animal; Histidine; HT29 Cells; Humans; Intermediate Filament Proteins; Keratins; Mice; Mice, Transgenic; Mutagenesis, Site-Directed; Phosphorylation; Solubility; Spodoptera | 1995 |
Experimental neuronal injury in the newborn lamb: a comparison of N-methyl-D-aspartic acid receptor blockade and nitric oxide synthesis inhibition on lesion size and cerebral hyperemia.
Topics: Animals; Animals, Newborn; Arginine; Brain Diseases; Cattle; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hemodynamics; Hyperemia; N-Methylaspartate; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Sheep | 1995 |
L-NAME reduces infarct volume in a filament model of transient middle cerebral artery occlusion in the rat pup.
Topics: Animals; Arginine; Arterial Occlusive Diseases; Cerebral Arteries; Cerebral Infarction; Disease Models, Animal; Ischemic Attack, Transient; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nylons; Rats; Rats, Inbred SHR | 1995 |
Glucose suppression of insulin secretion in chronically hyperglycemic fetal sheep.
Topics: Animals; Arginine; Blood Glucose; Cattle; Chronic Disease; Disease Models, Animal; Fetal Diseases; Hyperglycemia; Insulin; Insulin Secretion; Pancreas; Sheep | 1995 |
Perinatal nitric oxide synthase inhibition retards neonatal growth by inducing hypertrophic pyloric stenosis in rats.
Topics: Animals; Animals, Newborn; Arginine; Body Weight; Disease Models, Animal; Embryonic and Fetal Development; Female; Growth; Guanidines; Hypertrophy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pregnancy; Pyloric Stenosis; Rats | 1995 |
Dietary L-arginine attenuates blood pressure in mineralocorticoid-salt hypertensive rats.
Topics: Acetylcholine; Animals; Arginine; Body Weight; Desoxycorticosterone; Diet; Disease Models, Animal; Electrolytes; Hemodynamics; Hypertension; Male; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
Myocardial and coronary endothelial protective effects of acetylcholine after myocardial ischaemia and reperfusion in rats: role of nitric oxide.
Topics: Acetylcholine; Animals; Arginine; Blood Pressure; Coronary Vessels; Disease Models, Animal; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Molsidomine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Potassium Channel Blockers; Rats; Rats, Wistar; Vasodilator Agents | 1995 |
Role of endothelin-1 in hypertension induced by long-term inhibition of nitric oxide synthase.
Topics: Administration, Oral; Analysis of Variance; Animals; Arginine; Azepines; Blood Pressure; Desoxycorticosterone; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Hypertension; Indoles; Injections, Intravenous; Kidney; Male; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A | 1995 |
Effect of argatroban on microthrombi formation and brain damage in the rat middle cerebral artery thrombosis model.
Topics: Animals; Antithrombins; Arginine; Arterial Occlusive Diseases; Cerebral Arteries; Disease Models, Animal; Intracranial Embolism and Thrombosis; Male; Pipecolic Acids; Rats; Rats, Wistar; Sulfonamides; Thrombin; Time Factors | 1995 |
[Effect of chronic inhibition of nitric oxide synthesis on vascular structure: remodeling or growth?].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Basilar Artery; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Hypertension; Indoles; Muscle Development; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Verapamil | 1995 |
[Hemodynamic effects of sub-chronic NO synthase inhibition in conscious dogs: role of EDRF/NO in muscular exertion].
Topics: Acetylcholine; Animals; Arginine; Consciousness; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hemodynamics; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Physical Exertion | 1995 |
The role of nitric oxide in facial motoneuronal death.
Topics: Animals; Arginine; Cell Death; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Facial Nerve; Histocytochemistry; Male; Motor Neurons; NADPH Dehydrogenase; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Effects of chronic nitric oxide synthase inhibition on TNB-induced colitis in rats.
Topics: Animals; Arginine; Body Weight; Colitis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infusion Pumps, Implantable; Injections, Subcutaneous; Intestinal Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 1995 |
The role of nitric oxide and sulphydryls in gastric mucosal protection induced by sodium cromoglycate in rats.
Topics: Animals; Arginine; Cromolyn Sodium; Disease Models, Animal; Dose-Response Relationship, Drug; Ethanol; Ethylmaleimide; Gastric Mucosa; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sulfhydryl Compounds | 1995 |
Acute effect of L-arginine on hemodynamics and vascular capacitance in the canine pacing model of heart failure.
Topics: Animals; Arginine; Blood Pressure; Blood Volume; Cardiac Output; Cardiac Pacing, Artificial; Coronary Circulation; Disease Models, Animal; Dogs; Heart Arrest; Heart Failure; Nitric Oxide; Pulmonary Wedge Pressure; Vascular Capacitance; Vascular Resistance | 1995 |
Endothelium-derived nitric oxide does not modulate metabolic coronary vasodilation induced by tachycardia in dogs.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Heart; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oxygen Consumption; Tachycardia; Vasodilation | 1995 |
Inhibition of nitric oxide synthase during hemorrhagic shock increases hepatic injury.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Infusions, Intravenous; Liver; Liver Circulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic; Time Factors | 1995 |
Role of nitric oxide synthase isozymes in endotoxin-induced uveitis.
Topics: Animals; Aqueous Humor; Arginine; Cell Count; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Isoenzymes; Lipopolysaccharides; Male; Nitric Oxide Synthase; Nitroarginine; Ornithine; Phagocytes; Rats; Rats, Inbred Lew; Salmonella; Uveitis, Anterior | 1996 |
Analysis of responses to pentoxifylline in the pulmonary vascular bed of the cat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arginine; Bronchodilator Agents; Cats; Cyclooxygenase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Isoproterenol; Meclofenamic Acid; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentoxifylline; Prostaglandin Endoperoxides, Synthetic; Pulmonary Circulation; Thromboxane A2; Vasodilator Agents | 1996 |
Effect of halothane on phenylephrine-induced vascular smooth muscle contractions in endotoxin-exposed rat aortic rings.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Halothane; In Vitro Techniques; Lipopolysaccharides; Logistic Models; Male; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstrictor Agents | 1996 |
Endothelium-derived relaxing factor (nitric oxide) has a tonic vasodilating action on coronary collateral vessels.
Topics: Animals; Arginine; Collateral Circulation; Coronary Vessels; Dilatation, Pathologic; Disease Models, Animal; Dogs; Female; Hemodynamics; Humans; Male; Myocardial Ischemia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase | 1996 |
Aggravation of experimental allergic encephalomyelitis (EAE) by administration of nitric oxide (NO) synthase inhibitors.
Topics: Animals; Arginine; Brain; Cells, Cultured; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Guinea Pigs; Macrophages; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred Lew | 1996 |
Effects of nitric oxide synthase inhibition on the cardiovascular response to low output shock.
Topics: Analysis of Variance; Animals; Arginine; Cardiac Output, Low; Cardiovascular System; Dexamethasone; Disease Models, Animal; Nitric Oxide Synthase; Nitroarginine; Prospective Studies; Sheep; Shock, Cardiogenic | 1996 |
Endogenous nitric oxide and pulmonary vascular tone in the neonate.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Extracorporeal Membrane Oxygenation; Humans; Hypertension, Pulmonary; Hypoxia; Infant, Newborn; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pulmonary Circulation; Respiratory Mechanics; Swine; Vascular Resistance | 1996 |
Toxic dilatation of colon in a rat model of colitis is linked to an inducible form of nitric oxide synthase.
Topics: Animals; Arginine; Colitis; Colon; Dexamethasone; Dilatation; Disease Models, Animal; Enzyme Induction; Enzyme Inhibitors; Guanidines; Hypoxanthines; Inflammation; Male; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nifedipine; Nitric Oxide Synthase; Peroxidase; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid | 1996 |
Cardiac and regional haemodynamics, inducible nitric oxide synthase (NOS) activity, and the effects of NOS inhibitors in conscious, endotoxaemic rats.
Topics: Animals; Arginine; Cardiac Output; Disease Models, Animal; Enzyme Induction; Hemodynamics; Hypotension; Lipopolysaccharides; Lung; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Reproducibility of Results; Stroke Volume; Tachycardia | 1995 |
Effects of three inhibitors of nitric oxide synthase on host resistance to bacterial infection.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli Infections; Female; Mice; Mice, Inbred BALB C; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Ornithine; Prospective Studies; Random Allocation | 1996 |
Correlation between brain nitric oxide synthase activity and opiate withdrawal.
Topics: Animals; Arginine; Cerebellum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Injections, Subcutaneous; Male; Mice; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Stereoisomerism; Substance Withdrawal Syndrome | 1996 |
L-arginine decreases infarct size in rats exposed to environmental tobacco smoke.
Topics: Animals; Aorta, Abdominal; Arginine; Blood Pressure; Carbon Monoxide; Disease Models, Animal; Endothelium, Vascular; Environmental Exposure; Heart Rate; Isomerism; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Nicotine; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Tobacco Smoke Pollution | 1996 |
A selective inhibitor of inducible in nitric oxide synthase prolongs survival in a rat model of bacterial peritonitis: comparison with two nonselective strategies.
Topics: Animals; Anti-Bacterial Agents; Arginine; Disease Models, Animal; Enzyme Inhibitors; Escherichia coli Infections; Gram-Negative Bacterial Infections; Hemoglobins; Leukocyte Count; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peritonitis; Random Allocation; Rats; Rats, Sprague-Dawley; Sepsis | 1996 |
Nitric oxide synthase inhibition versus norepinephrine for the treatment of hyperdynamic sepsis in sheep.
Topics: Animals; Arginine; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Hemodynamics; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Oxygen Consumption; Prospective Studies; Sepsis; Sheep; Time Factors; Vasoconstrictor Agents | 1996 |
Nitric oxide donor alleviates ovariectomy-induced bone loss.
Topics: Absorptiometry, Photon; Analysis of Variance; Animals; Arginine; Bone Density; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Humans; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Osteoporosis, Postmenopausal; Ovariectomy; Rats; Rats, Sprague-Dawley | 1996 |
Increasing nitric oxide production improves survival in experimental hemorrhagic shock.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Disease Models, Animal; Enzyme Inhibitors; Male; Nitric Oxide; omega-N-Methylarginine; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Resuscitation; Shock, Hemorrhagic | 1996 |
Vasoconstrictor responsiveness of the rat mesenteric arterial bed in cirrhosis.
Topics: Adenosine Triphosphate; Animals; Arginine; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Liver Cirrhosis, Experimental; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Phenobarbital; Rats; Rats, Wistar; Vasopressins | 1996 |
Antithrombotic actions of the thrombin inhibitor, argatroban, in a canine model of coronary cyclic flow: comparison with heparin.
Topics: Angina, Unstable; Animals; Antithrombins; Arginine; Coronary Vessels; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Heparin; Male; Pipecolic Acids; Sulfonamides; Thrombin Time; Time Factors | 1996 |
Effects of a thrombin inhibitor, argatroban, on ischemic brain damage in the rat distal middle cerebral artery occlusion model.
Topics: Animals; Antithrombins; Arginine; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Male; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Sulfonamides | 1996 |
Inhibition of NO synthase in the posterior hypothalamus increases blood pressure in the rat.
Topics: Animals; Arginine; Blood Pressure; Data Interpretation, Statistical; Disease Models, Animal; Enzyme Inhibitors; Hypertension; Hypothalamus, Posterior; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar | 1995 |
Effect of supplemental L-arginine in a chemical-induced model of colorectal cancer.
Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Arginine; Carcinogens; Cell Division; Colorectal Neoplasms; Dimethylhydrazines; Disease Models, Animal; Lymphocyte Activation; Male; Rats; Rats, Wistar; T-Lymphocytes; Thymus Gland | 1996 |
Cerebral metabolic recovery from deep hypothermic circulatory arrest after treatment with arginine and nitro-arginine methyl ester.
Topics: Animals; Arginine; Brain; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Electron Transport Complex IV; Enzyme Inhibitors; Glucose; Heart Arrest, Induced; Hemoglobins; Hydrogen-Ion Concentration; Hypothermia, Induced; Injections, Intravenous; Magnetic Resonance Spectroscopy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidation-Reduction; Oxygen Consumption; Oxyhemoglobins; Phosphates; Reperfusion; Rewarming; Spectrophotometry, Infrared; Swine | 1996 |
Antithrombotic activity of argatroban in experimental thrombosis in the rabbit.
Topics: Animals; Antithrombins; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Artery; Infusions, Intravenous; Pipecolic Acids; Rabbits; Sulfonamides; Thrombosis | 1996 |
Effects of inogatran, a new low-molecular-weight thrombin inhibitor, in rat models of venous and arterial thrombosis, thrombolysis and bleeding time.
Topics: Animals; Antithrombins; Arginine; Aspirin; Bleeding Time; Disease Models, Animal; Fibrinolytic Agents; Glycine; Heparin; Male; Molecular Weight; Pipecolic Acids; Piperidines; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombolytic Therapy; Thrombophlebitis; Thrombosis | 1996 |
Intrathecal infusion of the nitric oxide synthase inhibitor N-methyl L-arginine after experimental spinal cord injury in guinea pigs.
Topics: Animals; Arginine; Disease Models, Animal; Female; Guinea Pigs; Injections, Spinal; Nitric Oxide Synthase; Spinal Cord Injuries | 1996 |
Anticonvulsant effects of 7-nitroindazole in rodents with reflex epilepsy may result from L-arginine accumulation or a reduction in nitric oxide or L-citrulline formation.
Topics: Animals; Anticonvulsants; Arginine; Blood Pressure; Citrulline; Disease Models, Animal; Epilepsy; Female; Heart Rate; Indazoles; Male; Mice; Mice, Inbred DBA; Motor Activity; Nitric Oxide; Nitric Oxide Synthase; Noise; Rats; Rats, Inbred Strains; Reflex; Seizures | 1996 |
Induction of thrombolysis and prevention of thrombus formation by local drug delivery with a double-occlusion balloon catheter.
Topics: Angioscopy; Animals; Anticoagulants; Antithrombins; Arginine; Catheterization; Coronary Angiography; Coronary Thrombosis; Coronary Vessels; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Heparin; Injections, Intralesional; Pipecolic Acids; Plasminogen Activators; Sulfonamides; Thrombolytic Therapy; Treatment Outcome | 1996 |
Local treatment with an antithrombotic drug reduces thrombus size in coronary and peripheral thrombosed arteries.
Topics: Angioscopy; Animals; Antithrombins; Arginine; Batroxobin; Coronary Angiography; Coronary Thrombosis; Coronary Vessels; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Fibrinolytic Agents; Heparin; Infusions, Intravenous; Injections, Intralesional; Pipecolic Acids; Reference Values; Sulfonamides; Treatment Outcome | 1996 |
Impaired insulin secretion and excessive hepatic glucose production are both early events in the diabetic GK rat.
Topics: Age Factors; Animals; Arginine; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glucose; Insulin; Insulin Resistance; Insulin Secretion; Liver; Muscle, Skeletal; Rats; Rats, Mutant Strains; Rats, Wistar | 1996 |
Nitric oxide in brain death related cardiovascular dysfunction.
Topics: Animals; Arginine; Brain Death; Disease Models, Animal; Dogs; Fourier Analysis; Hemodynamics; Male; Nitric Oxide; Nitrites; Time Factors | 1996 |
Pancreatic A-cell function in the partially pancreatectomized Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Insulin; Islets of Langerhans; Male; Niacinamide; Organ Size; Pancreatectomy; Rats | 1996 |
New model for in vivo studies of pharmacological interventions with endogenous fibrinolysis: effects of thrombin inhibitors.
Topics: Animals; Antithrombins; Arginine; Batroxobin; Boron Compounds; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrinolysis; Injections, Intravenous; Male; Oligopeptides; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombin | 1996 |
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Hydroxyproline; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lysine; Male; Oxidation-Reduction; Random Allocation; Rats; Rats, Inbred BB; Spectrometry, Fluorescence | 1996 |
Nitric oxide synthase is not involved in cardiac contractile dysfunction in a rat model of endotoxemia without shock.
Topics: Animals; Arginine; Blood Pressure; Dexamethasone; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Isothiuronium; Myocardial Contraction; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1997 |
Arginine reduces kidney collagen accumulation, cross-linking, lipid peroxidation, glycoxidation, kidney weight and albuminuria in the diabetic kk mouse.
Topics: Albuminuria; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glucose; Glycosylation; Hydroxyl Radical; Kidney; Lipid Peroxidation; Mice; Mice, Inbred Strains; Nitric Oxide; Organ Size; Oxidation-Reduction | 1997 |
Urinary bladder-urethral sphincter dysfunction in mice with targeted disruption of neuronal nitric oxide synthase models idiopathic voiding disorders in humans.
Topics: Animals; Arginine; Disease Models, Animal; Electric Stimulation; Endothelium, Vascular; Humans; Hypertrophy; Male; Mice; Mice, Inbred C57BL; Muscle Contraction; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Urethra; Urinary Bladder; Urination Disorders; Urothelium | 1997 |
Adjuvant effect of argatroban on staphylokinase induced thrombolysis of platelet rich thrombi in rat mesenteric venules in vivo.
Topics: Animals; Antithrombins; Arginine; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Fibrinolysis; Fibrinolytic Agents; Image Processing, Computer-Assisted; Male; Metalloendopeptidases; Microscopy, Electron; Pipecolic Acids; Rats; Rats, Wistar; Recombinant Proteins; Sulfonamides; Thrombosis | 1997 |
Glycation of collagen in hypertriglyceridemic rats.
Topics: Animals; Arginine; Collagen; Disease Models, Animal; Glycosylation; Hypertriglyceridemia; Lipid Peroxidation; Lysine; Male; Protein Processing, Post-Translational; Rats; Rats, Wistar; Skin; Spectrometry, Fluorescence | 1997 |
L-arginine reverses indomethacin-induced inhibition of inflammatory fluid secretion of the feline gall bladder.
Topics: Animals; Arginine; Cats; Cholecystitis; Chronic Disease; Cyclooxygenase Inhibitors; Disease Models, Animal; Gallbladder; Humans; Indomethacin; Inflammation Mediators; Nitric Oxide; Prostaglandins | 1997 |
In vivo evaluation of DX-9065a, a synthetic factor Xa inhibitor, in experimental vein graft.
Topics: Animals; Anticoagulants; Antithrombins; Arginine; Blood Vessel Prosthesis; Disease Models, Animal; Factor Xa Inhibitors; Graft Occlusion, Vascular; Heparin; Male; Microscopy, Electron, Scanning; Naphthalenes; Pipecolic Acids; Propionates; Rabbits; Sulfonamides; Thrombosis | 1996 |
beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy.
Topics: Adenoviridae; Animals; Arginine; beta-Galactosidase; Blood Glucose; Body Weight; Carrier Proteins; Disease Models, Animal; Eating; Genetic Therapy; Glucose; Immunoblotting; In Vitro Techniques; Infusions, Intra-Arterial; Insulin; Islets of Langerhans; Leptin; Male; Pancreas; Perfusion; Proteins; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, Leptin; Time Factors | 1997 |
Reversal by L-arginine of a dysfunctional arginine/nitric oxide pathway in the endothelium of the genetic diabetic BB rat.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Cohort Studies; Diabetes Mellitus, Type 1; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Muscle Relaxation; Nitric Oxide Synthase; Nitroglycerin; Rats; Rats, Inbred BB | 1997 |
Inhibition of nitric oxide modulates the effect of oral arginine supplementation in acute liver injury.
Topics: Acute Disease; Administration, Oral; Alanine Transaminase; Analysis of Variance; Animals; Arginine; Aspartate Aminotransferases; Bacterial Translocation; Bilirubin; Chemical and Drug Induced Liver Injury; Colony Count, Microbial; Disease Models, Animal; DNA; Enzyme Inhibitors; Food, Fortified; Galactosamine; Intestinal Mucosa; Liver Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; RNA | 1997 |
Attenuated inhibition of adrenergic contraction by nitric oxide in injured guinea pig femoral artery.
Topics: Acetylcholine; Adrenergic Fibers; Animals; Arginine; Capsaicin; Catheterization; Disease Models, Animal; Femoral Artery; Guinea Pigs; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Tunica Intima; Vasoconstriction | 1997 |
[Contribution of L-arginine-derived nitric oxide to the structural integrity of coronary artery and cardiac interstitium, and to the regulation of sympathetic nerve activity: assessment using a rat model produced by chronic nitric oxide inhibition].
Topics: Animals; Arginine; Catecholamines; Chronic Disease; Coronary Vessels; Disease Models, Animal; Fibrosis; Heart Rate; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renin; Sympathetic Nervous System | 1997 |
Inhibition of nitric oxide synthases enhances the effect of ACTH in hemorrhagic shock.
Topics: Animals; Arginine; Cosyntropin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Shock, Hemorrhagic | 1997 |
Intrapericardial delivery of L-arginine reduces the increased severity of ventricular arrhythmias during sympathetic stimulation in dogs with acute coronary occlusion: nitric oxide modulates sympathetic effects on ventricular electrophysiological properti
Topics: Animals; Arginine; Confounding Factors, Epidemiologic; Disease Models, Animal; Dogs; Electric Stimulation; Enzyme Inhibitors; Myocardial Contraction; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; omega-N-Methylarginine; Pericardium; Severity of Illness Index; Tachycardia, Ventricular | 1997 |
Antithrombotic and hemorrhagic effects of DX-9065a, a direct and selective factor Xa inhibitor: comparison with a direct thrombin inhibitor and antithrombin III-dependent anticoagulants.
Topics: Animals; Anticoagulants; Antithrombin III; Arginine; Bleeding Time; Blood Coagulation; Disease Models, Animal; Factor Xa Inhibitors; Hemorrhage; Heparin, Low-Molecular-Weight; Male; Naphthalenes; Peptide Hydrolases; Pipecolic Acids; Propionates; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombosis | 1997 |
Nitric oxide donors antagonize N-nitro-L-arginine and haloperidol catalepsy: potential implication for the treatment of Parkinsonism?
Topics: Animals; Arginine; Catalepsy; Disease Models, Animal; Haloperidol; Male; Molsidomine; Nitric Oxide Synthase; Nitroarginine; Parkinson Disease; Rats; Rats, Wistar; Vasodilator Agents | 1997 |
Measurement of changes in cerebral blood volume in spontaneously hypertensive rats following L-arginine infusion using dynamic susceptibility contrast MRI.
Topics: Animals; Arginine; Blood Volume; Brain; Contrast Media; Disease Models, Animal; Gadolinium DTPA; Hemodynamics; Hypertension, Malignant; Infusions, Intravenous; Magnetic Resonance Imaging; Nitric Oxide; Rats; Rats, Inbred SHR; Reference Values; Regional Blood Flow; Time Factors | 1998 |
Ecarin Clotting Time: a predictive coagulation assay for the antithrombotic activity of argatroban in the rat.
Topics: Animals; Antithrombins; Arginine; Arteriovenous Shunt, Surgical; Blood Coagulation Tests; Disease Models, Animal; Male; Pipecolic Acids; Rats; Rats, Inbred Strains; Reference Values; Sulfonamides; Thrombophlebitis; Thromboplastin; Thrombosis; Treatment Outcome | 1998 |
Comparative studies of an orally-active factor Xa inhibitor, YM-60828, with other antithrombotic agents in a rat model of arterial thrombosis.
Topics: Administration, Oral; Animals; Anticoagulants; Antithrombin III; Arginine; Carotid Artery Thrombosis; Disease Models, Animal; Factor Xa Inhibitors; Heparin; Infusions, Intravenous; Naphthalenes; Pipecolic Acids; Piperidines; Rats; Sulfonamides | 1998 |
Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Niacinamide; Rats; Rats, Wistar; Streptozocin; Tolbutamide | 1998 |
[Influence of mycobacterium on adaptive rearrangement in guinea pigs long exposed to polycystic aromatic hydrocarbon-containing agents].
Topics: Adaptation, Biological; Animals; Arginine; Bone Marrow; Cell Membrane; Disease Models, Animal; Guinea Pigs; Liver; Lung; Methionine; Mycobacterium tuberculosis; Polycyclic Aromatic Hydrocarbons; Spleen; Tuberculosis | 1998 |
Killing of blood stage Plasmodium vinckei petteri by spleen macrophages through L-arginine dependent mechanism.
Topics: Animals; Arginine; BCG Vaccine; Cells, Cultured; Disease Models, Animal; Female; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Mice, Inbred BALB C; omega-N-Methylarginine; Plasmodium; Rodentia; Spleen; Time Factors | 1997 |
Effects of dermatan sulfate, a heparin cofactor II mediated thrombin inhibitor, on the endotoxin-induced disseminated intravascular coagulation model in the rat: comparison with low-molecular weight heparin, nafamostat mesilate and argathroban.
Topics: Animals; Arginine; Benzamidines; Dermatan Sulfate; Disease Models, Animal; Disseminated Intravascular Coagulation; Endotoxins; Guanidines; Heparin; Heparin Cofactor II; Male; Molecular Weight; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Sulfonamides | 1998 |
Role of endothelin and nitric oxide imbalance in the pathogenesis of hypoxia-induced arterial hypertension.
Topics: Acetamides; Animals; Arginine; Blood Pressure; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelins; Hypertension, Renal; Hypoxia; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Renal Circulation | 1998 |
Tissue plasminogen activator (tPA) inhibits interleukin-1 induced acute lung leak.
Topics: Animals; Arginine; Bronchoalveolar Lavage; Cell Count; Disease Models, Animal; Drug Administration Schedule; Injections, Intraperitoneal; Instillation, Drug; Interleukin-1; Male; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Tissue Plasminogen Activator; Trachea | 1998 |
L-arginine: effect on reperfusion injury after heart transplantation.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Follow-Up Studies; Heart Transplantation; Hypothermia, Induced; Myocardial Contraction; Myocardial Reperfusion Injury; Nitroprusside; Rats; Regional Blood Flow; Vasodilation; Vasodilator Agents; Ventricular Pressure | 1998 |
Studies of arginine metabolism and salt sensitivity in the Dahl/Rapp rat models of hypertension.
Topics: Alanine; Animals; Arginine; Argininosuccinate Synthase; Blood Pressure; Body Weight; Citrulline; Disease Models, Animal; Hypertension; Kidney; Liver; Male; Ornithine; Rats; Sodium Chloride, Dietary; Urea | 1998 |
Regulation of electrolyte transport by nitric oxide in the mouse cecum.
Topics: Animals; Arginine; Biological Transport; Cecum; Colitis; Disease Models, Animal; Electrolytes; Female; Immunohistochemistry; Mice; Mice, Inbred C3H; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II | 1998 |
Evaluation of gene therapy for citrullinaemia using murine and bovine models.
Topics: Adenoviruses, Human; Amino Acid Metabolism, Inborn Errors; Ammonia; Animals; Arginine; Argininosuccinate Synthase; Benzoates; Benzoic Acid; Cattle; Citrulline; Disease Models, Animal; Evaluation Studies as Topic; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Liver; Mice; Nitrogen; Treatment Outcome; Urea | 1998 |
Involvement of nitric oxide and prostaglandins in gastroprotection induced by bacterial lipopolysaccharide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Dexamethasone; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia coli; Ethanol; Gastric Acid; Gastric Mucosa; Gene Expression; Lipopolysaccharides; Male; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Pepsin A; Polymerase Chain Reaction; Rats; Rats, Wistar; Regional Blood Flow; RNA, Messenger; Stomach; Stomach Diseases | 1998 |
Effects of moderate, central fluid percussion traumatic brain injury on nitric oxide synthase activity in rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Excitatory Amino Acid Agonists; Ionomycin; Ionophores; Male; N-Methylaspartate; Nitric Oxide Synthase; Potassium Chloride; Rats; Rats, Sprague-Dawley | 1998 |
Increased neuropeptide Y pressor activity in Goldblatt hypertensive rats: in vivo studies with BIBP 3226.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Renovascular; Kidney; Male; Neuropeptide Y; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery | 1998 |
Endogenous neuropeptide Y mediates vasoconstriction during endotoxic and hemorrhagic shock.
Topics: Animals; Arginine; Blood Pressure; Disease Models, Animal; Heart Rate; Lipopolysaccharides; Male; Neuropeptide Y; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Shock, Hemorrhagic; Shock, Septic; Vasoconstriction | 1998 |
Aromatic hydroxylation in animal models of diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Fructosamine; Hydroxylation; Kidney; Lysine; Malondialdehyde; Mice; Rats; Rats, Inbred BB; Rats, Sprague-Dawley; Streptozocin; Tyrosine | 1998 |
Influence of L-arginine, aminoguanidine, and NG-nitro-L-arginine methyl ester (L-name) on the survival rate in a rat model of hemorrhagic shock.
Topics: Animals; Arginine; Aspartate Aminotransferases; Blood Pressure; Creatinine; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanidines; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Survival Rate | 1999 |
L-arginine: a unique amino acid for restoring the depressed macrophage functions after trauma-hemorrhage.
Topics: Animals; Arginine; Disease Models, Animal; Fluid Therapy; Immunity, Cellular; Infusions, Intravenous; Interleukin-1; Interleukin-6; Macrophages; Male; Nitric Oxide Donors; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Soft Tissue Injuries | 1999 |
Oral administration of L-arginine reduces intimal hyperplasia in balloon-injured rat carotid arteries.
Topics: Administration, Oral; Animals; Arginine; Carotid Artery Injuries; Carotid Artery, Common; Catheterization; Cell Division; Disease Models, Animal; Hyperplasia; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley | 1999 |
Porcine endotoxemic shock is associated with increased expired nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Base Sequence; Blotting, Western; Breath Tests; Disease Models, Animal; DNA Primers; Endotoxemia; Endotoxins; Enzyme Inhibitors; Escherichia coli; Hemodynamics; Molecular Sequence Data; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Polymerase Chain Reaction; Respiration; Shock, Septic; Swine; Time Factors | 1999 |
Role of nitric oxide in restenosis after experimental balloon angioplasty in the hypercholesterolemic rabbit: effects on neointimal hyperplasia and vascular remodeling.
Topics: Angiography; Angioplasty, Balloon; Animals; Arginine; Arteriosclerosis; Disease Models, Animal; Enzyme Inhibitors; Follow-Up Studies; Hypercholesterolemia; Hyperplasia; Iliac Artery; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Secondary Prevention; Thrombosis; Tunica Intima | 1999 |
Enhanced activity of carotid body chemoreceptors in rabbits with heart failure: role of nitric oxide.
Topics: Animals; Arginine; Carbon Dioxide; Cardiac Pacing, Artificial; Carotid Body; Chemoreceptor Cells; Disease Models, Animal; Heart Failure; Hypoxia; Male; Nitric Oxide Synthase; Nitroarginine; Oxygen; Partial Pressure; Rabbits | 1999 |
Protective effect of L-arginine on hypercholesterolemia-enhanced renal ischemic injury.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Arginine; Cells, Cultured; Cholesterol, Dietary; Disease Models, Animal; Hypercholesterolemia; Kidney; Kidney Function Tests; Kidney Tubules, Collecting; L-Lactate Dehydrogenase; Male; Nitric Oxide; Rats; Rats, Wistar; Reference Values; Regional Blood Flow | 1999 |
L-Arginine supplementation increases mesangial cell injury and subsequent tissue fibrosis in experimental glomerulonephritis.
Topics: Animals; Antilymphocyte Serum; Arginine; Cell Count; Disease Models, Animal; Fibrosis; Glomerular Mesangium; Glomerulonephritis; Macrophages; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger; T-Lymphocytes | 1999 |
Pulmonary artery endothelium-dependent vasodilation is impaired in a chicken model of pulmonary hypertension.
Topics: Acetylcholine; Animals; Arginine; Calcimycin; Chickens; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hypertension, Pulmonary; Ionophores; Male; NG-Nitroarginine Methyl Ester; Nitroprusside; Papaverine; Pulmonary Artery; Vasodilation; Vasodilator Agents | 1999 |
Relationship between the histopathology of the endocrine-exocrine pancreas parenchyma and beta-cell function in the Chinese hamster CHIG/Han subline.
Topics: Animals; Arginine; Blood Glucose; Cell Count; Cell Separation; Cells, Cultured; Cricetinae; Cricetulus; Culture Media, Conditioned; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Glucose; Immunoenzyme Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male | 1999 |
Modulation of systemic hemodynamics by exogenous L-arginine in normal and bacteremic sheep.
Topics: Acidosis; Animals; Arginine; Bacteremia; Blood Gas Analysis; Blood Pressure; Disease Models, Animal; Escherichia coli Infections; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Hypoxia; Injections, Intravenous; Lactic Acid; Leukopenia; Prospective Studies; Pulmonary Wedge Pressure; Respiration, Artificial; Sheep; Treatment Outcome; Vascular Resistance | 1999 |
Cerebral hemodynamic effects of phenylephrine and L-arginine after cortical impact injury.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Pressure; Body Temperature; Body Water; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Disease Models, Animal; Infusions, Intravenous; Intracranial Hypertension; Intracranial Pressure; Laser-Doppler Flowmetry; Male; Phenylephrine; Prospective Studies; Random Allocation; Rats; Rats, Long-Evans; Treatment Outcome; Vasoconstrictor Agents | 1999 |
Influence of arginine dietary supplementation on healing colonic anastomosis in the rat.
Topics: Anastomosis, Surgical; Animals; Arginine; Colitis; Collagen; Colon; Dietary Supplements; Disease Models, Animal; Follow-Up Studies; Male; Pressure; Rats; Rats, Sprague-Dawley; Rupture; Time Factors; Wound Healing | 1999 |
Increased cerebral blood flow but no reversal or prevention of vasospasm in response to L-arginine infusion after subarachnoid hemorrhage.
Topics: Animals; Arginine; Carotid Artery, Internal; Cerebral Angiography; Cerebrovascular Circulation; Disease Models, Animal; Infusions, Intra-Arterial; Infusions, Intravenous; Macaca fascicularis; Middle Cerebral Artery; Nitric Oxide Synthase; Random Allocation; Subarachnoid Hemorrhage; Vasospasm, Intracranial | 2000 |
Correction of ornithine accumulation prevents retinal degeneration in a mouse model of gyrate atrophy of the choroid and retina.
Topics: Amino Acids; Animals; Arginine; Choroid; Disease Models, Animal; Electroretinography; Gyrate Atrophy; Mice; Mice, Knockout; Ornithine; Ornithine-Oxo-Acid Transaminase; Retina; Retinal Degeneration | 2000 |
Nitric oxide affects angiotensin II pressor response: possible mechanism of attenuated pressor response during pregnancy and etiology of pregnancy-induced hypertension.
Topics: Angiotensin II; Animals; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Female; Hypertension; Injections, Intraperitoneal; Nitric Oxide; omega-N-Methylarginine; Pregnancy; Pregnancy Complications, Cardiovascular; Pressoreceptors; Probability; Rats; Rats, Wistar; Reference Values; Sensitivity and Specificity; Software; Vasoconstrictor Agents | 2000 |
Role of nitric oxide in pentylenetetrazol-induced seizures: age-dependent effects in the immature rat.
Topics: Age Factors; Animals; Animals, Newborn; Arginine; Brain; Catalysis; Disease Models, Animal; Electroencephalography; Epilepsy; Female; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Rats; Rats, Sprague-Dawley | 2000 |
Pulmonary blast injury increases nitric oxide production, disturbs arginine metabolism, and alters the plasma free amino acid pool in rabbits during the early posttraumatic period.
Topics: Amino Acids; Animals; Arginine; Blast Injuries; Disease Models, Animal; Male; Nitrates; Nitric Oxide; Nitrites; Rabbits; Respiratory Distress Syndrome | 2000 |
Impaired nitric oxide production in coronary endothelial cells of the spontaneously diabetic BB rat is due to tetrahydrobiopterin deficiency.
Topics: Animals; Arginine; Biopterins; Calcium; Calmodulin; Chromatography, High Pressure Liquid; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; GTP Cyclohydrolase; Immunoblotting; Kinetics; NADP; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Protein Isoforms; Pteridines; Pterins; Rats; Rats, Mutant Strains | 2000 |
Activity of a sub-cutaneously administered novel mixed micellar formulation of argatroban in rat and rabbit models of venous thrombosis.
Topics: Animals; Anticoagulants; Antithrombins; Arginine; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Coagulation Tests; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Compounding; Drug Evaluation, Preclinical; Hemostatics; Heparin; Injections, Subcutaneous; Male; Micelles; Pipecolic Acids; Rabbits; Rats; Sulfonamides; Thromboplastin; Venous Thrombosis | 2000 |
Combination of a direct thrombin inhibitor and a platelet glycoprotein IIb/IIIa blocking peptide facilitates and maintains reperfusion of platelet-rich thrombus with alteplase.
Topics: Animals; Antithrombins; Arginine; Bleeding Time; Blood Flow Velocity; Blood Platelets; Disease Models, Animal; Drug Combinations; Drug Evaluation; Female; Femoral Artery; Fibrinolytic Agents; Heparin; Male; Partial Thromboplastin Time; Peptides; Peptides, Cyclic; Pipecolic Acids; Plasminogen Activators; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Reperfusion; Sulfonamides; Sulfoxides; Thrombosis; Tissue Plasminogen Activator | 2000 |
Evaluation of oxidative stress in experimental colitis: effects of L-arginine-nitric oxide pathway manipulation.
Topics: Analysis of Variance; Animals; Arginine; Colitis; Colon; Disease Models, Animal; Enzyme Inhibitors; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Trinitrobenzenesulfonic Acid | 2000 |
Effects of L-arginine on prevention and treatment of lithium-pilocarpine-induced status epilepticus.
Topics: Animals; Arginine; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Lithium; Male; Muscarinic Agonists; Nitric Oxide; Pilocarpine; Rats; Rats, Wistar; Seizures; Status Epilepticus; Survival Rate | 2000 |
Effect of L-arginine on endothelial injury and hemostasis in rabbit endotoxin shock.
Topics: Acetylcholine; Animals; Arginine; Blood Gas Analysis; Calcimycin; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Hemostasis; Ionophores; Lipopolysaccharides; Male; Monocytes; NG-Nitroarginine Methyl Ester; Nitroprusside; Phenylephrine; Rabbits; Shock, Septic; Thromboplastin; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Weight Loss | 2000 |
Role of neuropeptide Y in the development of two-kidney, one-clip renovascular hypertension in the rat.
Topics: Animals; Arginine; Blood Pressure Determination; Disease Models, Animal; Hemodynamics; Hypertension, Renal; Injections, Intravenous; Kidney; Male; Neuropeptide Y; Probability; Rats; Rats, Sprague-Dawley; Reference Values; Renin | 2000 |
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia.
Topics: Angiography; Animals; Arginine; Blood Pressure; Body Weight; Collateral Circulation; Cyclic GMP; Disease Models, Animal; Heart Rate; Hindlimb; Homocysteine; Hyperhomocysteinemia; Immunohistochemistry; Ischemia; Laser-Doppler Flowmetry; Muscle, Skeletal; Neovascularization, Physiologic; Nitrates; Nitrites; Rats; Regional Blood Flow; Time Factors | 2000 |
Nitric oxide synthase activity in retinas from non-insulin-dependent diabetic Goto-Kakizaki rats: correlation with blood-retinal barrier permeability.
Topics: Animals; Arginine; Blood Glucose; Blood-Retinal Barrier; Blotting, Western; Densitometry; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Fluorescein Angiography; Guanidines; Immunohistochemistry; Interleukin-1; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats; Rats, Inbred Strains; Rats, Wistar; Retina; Retinal Vessels | 2000 |
Pressure overload increases GATA4 binding activity via endothelin-1.
Topics: Analysis of Variance; Animals; Arginine; Cells, Cultured; Disease Models, Animal; DNA; DNA-Binding Proteins; Endothelin Receptor Antagonists; Endothelin-1; GATA4 Transcription Factor; GATA6 Transcription Factor; Hypertension; Myocardium; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factors; Vasopressins; Ventricular Function, Left | 2001 |
A mutation in alpha-tropomyosin(slow) affects muscle strength, maturation and hypertrophy in a mouse model for nemaline myopathy.
Topics: Amino Acid Substitution; Animals; Arginine; Disease Models, Animal; Dissection; Female; Glycolysis; Humans; Hypertrophy; Inclusion Bodies; Methionine; Mice; Mice, Inbred Strains; Mice, Transgenic; Microtubules; Muscle Development; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle Weakness; Muscle, Skeletal; Myopathies, Nemaline; Oxidation-Reduction; Point Mutation; RNA, Messenger; Sarcoplasmic Reticulum; Strontium; Tropomyosin | 2001 |
Increased L-arginine uptake and inducible nitric oxide synthase activity in aortas of rats with heart failure.
Topics: Animals; Aorta; Arginine; Blood Pressure; Disease Models, Animal; DNA Primers; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart Failure; Heart Rate; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Tritium; Tumor Necrosis Factor-alpha; Ventricular Pressure | 2001 |
Glutamine ameliorates mechanical obstruction-induced intestinal injury.
Topics: Administration, Oral; Animals; Arginine; Cecum; Disease Models, Animal; Glutamine; Ileum; Intestinal Mucosa; Intestinal Obstruction; Intestine, Small; Male; Rats; Rats, Sprague-Dawley | 2001 |
Role of soy diet and L-arginine in cyclosporin-A-induced osteopenia in rats.
Topics: Animals; Arginine; Body Weight; Bone Density; Bone Diseases, Metabolic; Calcium; Cyclosporine; Diet; Disease Models, Animal; Drug Therapy, Combination; Immunosuppressive Agents; Injections, Intraperitoneal; Male; Pelvic Bones; Radiography; Rats; Rats, Sprague-Dawley; Soybean Proteins; Spine | 2001 |
Do recurrent febrile convulsions decrease the threshold for pilocarpine-induced seizures? Effects of nitric oxide.
Topics: Animals; Arginine; Behavior, Animal; Body Temperature; Disease Models, Animal; Disease Progression; Disease Susceptibility; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Hyperthermia, Induced; Immersion; Injections, Intraperitoneal; Nitric Oxide; Pilocarpine; Rats; Rats, Wistar; Reaction Time; Risk Assessment; Seizures; Seizures, Febrile | 2001 |
Impaired modulation of sympathetic vasoconstriction in contracting skeletal muscle of rats with chronic myocardial infarctions: role of oxidative stress.
Topics: Animals; Arginine; Chronic Disease; Coronary Vessels; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; Free Radical Scavengers; Hemodynamics; Hindlimb; Ligation; Malondialdehyde; Muscle, Skeletal; Myocardial Infarction; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Oxygen; Phenotype; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sympathetic Nervous System; Vasoconstriction; Ventricular Dysfunction, Left | 2001 |
Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arthritis, Experimental; Benzhydryl Compounds; Binding, Competitive; Cell Line; Complement C3a; Complement Inactivator Proteins; Disease Models, Animal; Edema; Guinea Pigs; Hindlimb; Humans; Injections, Intraperitoneal; Leukocytosis; Male; Membrane Proteins; Mice; Muscle Contraction; Neutrophil Infiltration; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Receptors, Complement; Tumor Cells, Cultured | 2001 |
Nitric oxide deficiency contributes to impairment of airway relaxation in cystic fibrosis mice.
Topics: Animals; Arginine; Bronchoconstriction; Cystic Fibrosis; Dinoprostone; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Male; Mice; Mice, Inbred CFTR; Muscle Relaxation; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Substance P; Trachea | 2001 |
Experimental evidence suggesting that nitric oxide diffuses from tissue into blood but not from blood into tissue.
Topics: Animals; Arginine; Disease Models, Animal; Ditiocarb; Electron Spin Resonance Spectroscopy; Erythrocytes; Ferrous Compounds; Hemoglobins; Infusions, Intravenous; Intestinal Diseases; Intestinal Mucosa; Ischemia; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley | 2001 |
Thrombin promotes fibroblast proliferation during the early stages of experimental radiation pneumonitis.
Topics: Animals; Antithrombin III; Antithrombins; Arginine; Biological Assay; Bronchoalveolar Lavage Fluid; Cell Division; Cell Separation; Cells, Cultured; Disease Models, Animal; Fibroblasts; Growth Substances; Lung; Male; Pipecolic Acids; Radiation Injuries, Experimental; Radiation Pneumonitis; Rats; Rats, Wistar; Specific Pathogen-Free Organisms; Sulfonamides; Thrombin | 2001 |
[Changes of nitric oxide system during acute myocardial ischemic reperfusion].
Topics: Animals; Arginine; Disease Models, Animal; Dogs; Myocardial Ischemia; Myocardial Reperfusion; Nitric Oxide | 2000 |
Extremely short small bowel induces focal tubulointerstitial fibrosis.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Fibrosis; Immunohistochemistry; Kidney; Male; Orotic Acid; Rats; Rats, Sprague-Dawley; Short Bowel Syndrome | 2001 |
Contribution of nitric oxide to the protective effects of ischemic preconditioning in ischemia-reperfused rat kidneys.
Topics: Animals; Arginine; Blood Pressure; Caspase 3; Caspases; Disease Models, Animal; Enzyme Inhibitors; Glomerular Filtration Rate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Ischemic Preconditioning; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reperfusion Injury; Sodium | 2001 |
The role of the interaction between endogenous opioids and nitric oxide in the pathophysiology of ethanol-induced gastric damage in cholestatic rats.
Topics: Alcohol Deterrents; Animals; Arginine; Bile Ducts; Cholestasis; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Ligation; Male; Naltrexone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Opioid Peptides; Rats; Stomach Ulcer | 2001 |
The role of nitric oxide in the gastric acid secretion induced by ischemia-reperfusion in the pylorus-ligated rat.
Topics: Animals; Arginine; Disease Models, Animal; Enzyme Inhibitors; Free Radical Scavengers; Gastric Acid; Gastric Mucosa; Ligation; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Penicillamine; Pylorus; Rats; Rats, Inbred Strains; Reperfusion Injury; Stomach; Stomach Ulcer; Superoxide Dismutase; Time Factors | 2001 |
Orotic acid, a new promoter for experimental liver carcinogenesis.
Topics: 1,2-Dimethylhydrazine; Animals; Arginine; Carcinogens; Diet; Disease Models, Animal; DNA; gamma-Glutamyltransferase; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Orotic Acid; Precancerous Conditions; Rats; Rats, Inbred F344; Thymidine; Thymine; Time Factors | 1984 |
Low arginine plasma levels do not aggravate renal blood flow after experimental renal ischaemia/reperfusion.
Topics: Animals; Arginase; Arginine; Disease Models, Animal; Hemodynamics; Ischemia; Kidney Diseases; Male; Probability; Random Allocation; Rats; Rats, Wistar; Renal Circulation; Reperfusion; Sensitivity and Specificity; Statistics, Nonparametric | 2001 |
Effect of L-arginine on the course of experimental colitis.
Topics: Acute Disease; Animals; Arginine; Body Weight; Chronic Disease; Colitis; Collagen; Colon; Disease Models, Animal; Female; Fibrosis; Inflammation; Intestinal Mucosa; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Strain-dependent differences in the pattern of aortic lipid deposition in cholesterol-fed rabbits.
Topics: Animals; Aorta, Thoracic; Arginine; Cholesterol, Dietary; Disease Models, Animal; Lipid Metabolism; Male; Nitric Oxide; Rabbits; Vitamin E | 2001 |
Hyperglycemia reduces coronary collateral blood flow through a nitric oxide-mediated mechanism.
Topics: Animals; Arginine; Collateral Circulation; Coronary Circulation; Disease Models, Animal; Dogs; Hyperglycemia; Microcirculation; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide | 2001 |
Insulin secretion to glucose as well as nonglucose stimuli is impaired in spontaneously diabetic Nagoya-Shibata-Yasuda mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Blood Glucose; Calcium Channel Agonists; Cell Separation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Stimulation, Chemical | 2001 |
Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Disease Models, Animal; Eflornithine; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Female; Granuloma; Interleukin-12; Liver; Liver Cirrhosis; Lung Diseases, Parasitic; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Mycobacterium avium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine Decarboxylase Inhibitors; Ovum; Proline; Schistosomiasis mansoni; Th1 Cells; Th2 Cells; Tuberculosis; Up-Regulation | 2001 |
Arginine reverses ethanol-induced inflammatory and fibrotic changes in liver despite continued ethanol administration.
Topics: Animals; Arginine; Cyclooxygenase 2; Disease Models, Animal; Down-Regulation; Drug Interactions; Endotoxins; Ethanol; Humans; Inflammation; Isoenzymes; Lipid Peroxidation; Liver; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Membrane Proteins; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Tyrosine | 2001 |
Effects of intracavernous administration of adrenomedullin on erectile function in rats.
Topics: Adrenomedullin; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Erectile Dysfunction; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Peptides; Phosphodiesterase Inhibitors; Piperidines; Quinazolines; Rats; Rats, Wistar | 2001 |
[Effects of relative imbalance between endothlin-1 and nitric oxide on pathogenesis of the ascaris-induced asthma in dogs].
Topics: Animals; Arginine; Ascaris; Asthma; Disease Models, Animal; Dogs; Endothelin-1; Enzyme Inhibitors; Female; Infusions, Intravenous; Male; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine | 1999 |
[The role of endogenous nitric oxide in airway hyperresponsiveness of asthmatic rats].
Topics: Animals; Arginine; Asthma; Disease Models, Animal; Enzyme Inhibitors; Hypersensitivity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar | 1999 |
[The role of nitric oxide in hyperdynamic circulation in portal hypertensive rats].
Topics: Animals; Arginine; Carbon Tetrachloride; Disease Models, Animal; Enzyme Inhibitors; Hemodynamics; Hypertension, Portal; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Portasystemic Shunt, Surgical; Rats; Rats, Sprague-Dawley | 1998 |
Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.
Topics: Anemia, Sickle Cell; Animals; Arginine; Citrulline; Disease Models, Animal; Erythrocyte Count; Erythrocytes; Hemoglobins; Humans; Kinetics; Mice; Mice, Transgenic; Oxygen; Potassium; Potassium Channels, Calcium-Activated | 2002 |
Experimental stereotactic gamma knife radiosurgery. Vascular contractility studies of the rat middle cerebral artery after chronic survival.
Topics: Animals; Arginine; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; Intracranial Arteriovenous Malformations; Male; Middle Cerebral Artery; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Papaverine; Potassium; Radiosurgery; Radiotherapy Dosage; Rats; Rats, Wistar; Uridine Triphosphate; Vasoconstriction; Vasodilation | 2002 |
High NaCl intake decreases both flow-induced dilation and pressure-induced myogenic tone in resistance arteries from normotensive rats: involvement of cyclooxygenase-2.
Topics: Animals; Arginine; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelium, Vascular; Indomethacin; Isoenzymes; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred WKY; Regional Blood Flow; Sodium Chloride, Dietary; Sulfonamides; Vasodilation | 2001 |
Hypolipidemic and antiperoxidative effect of coconut protein in hypercholesterolemic rats.
Topics: Animals; Arginine; Cholesterol; Cocos; Disease Models, Animal; Hypercholesterolemia; Hypolipidemic Agents; Lipid Peroxidation; Lipid Peroxides; Male; Plant Proteins; Rats; Rats, Sprague-Dawley; Triglycerides | 2001 |
Induction of arginase II in livers of bile duct-ligated rats.
Topics: Animals; Arginase; Arginine; Cholestasis; Disease Models, Animal; Enzyme Induction; Liver Cirrhosis; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2002 |
Chronic hypoxia increases MCA contractile response to U-46619 by reducing NO production and/or activity.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Atmosphere Exposure Chambers; Chronic Disease; Dietary Supplements; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Hypoxia; In Vitro Techniques; Middle Cerebral Artery; Nitric Oxide; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Functional and analytical evidence for scavenging of oxygen radicals by L-arginine.
Topics: Animals; Antioxidants; Arginine; Cytochrome c Group; Disease Models, Animal; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Heart Injuries; Luminescent Measurements; Magnetics; Male; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2002 |
Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors.
Topics: Acute Disease; Animals; Arginine; Body Temperature; Carrageenan; Disease Models, Animal; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Neurogenic Inflammation; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Spinal Cord | 2002 |
Quantitative in vivo assessment of arginine utilization and nitric oxide production in endotoxemia.
Topics: Animals; Arginine; Chromatography, Liquid; Disease Models, Animal; Endotoxemia; Lipopolysaccharides; Mass Spectrometry; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitrogen Isotopes; Protein Isoforms; Sepsis; Swine | 2002 |
L-arginine supplementation in hyperdynamic endotoxemic pigs: effect on nitric oxide synthesis by the different organs.
Topics: Analysis of Variance; Animals; Arginine; Disease Models, Animal; Endotoxemia; Enteral Nutrition; Escherichia coli Infections; Female; Hemodynamics; Hindlimb; Intestinal Mucosa; Kidney; Liver; Nitric Oxide; Sepsis; Swine; Viscera | 2002 |
Mild streptozotocin diabetes in the Göttingen minipig. A novel model of moderate insulin deficiency and diabetes.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Food; Glucagon; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Male; Niacinamide; Streptozocin; Swine, Miniature; Time Factors | 2002 |
Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia.
Topics: Animals; Arginine; Calcium; Carbachol; Cholinergic Agonists; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Iliac Artery; Impotence, Vasculogenic; In Vitro Techniques; Ischemia; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits; Vasoconstrictor Agents; Vasodilator Agents | 2002 |
Construction and phenotypic characterization of an auxotrophic mutant of Mycobacterium tuberculosis defective in L-arginine biosynthesis.
Topics: Animals; Arginine; Disease Models, Animal; Immunocompetence; Kinetics; Mice; Mice, Inbred DBA; Mice, SCID; Mutagenesis; Mycobacterium tuberculosis; Ornithine Carbamoyltransferase; Phenotype; Substrate Specificity; Tuberculosis, Pulmonary; Virulence | 2002 |
Protective effect of dietary supplementation with L-arginine and L-carnitine on hypoxia/reoxygenation-induced necrotizing enterocolitis in young mice.
Topics: Animals; Arginine; Carnitine; Dietary Supplements; Disease Models, Animal; Enterocolitis, Necrotizing; Hypoxia; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Necrosis; Thiobarbituric Acid Reactive Substances | 2002 |
Isolation, transplantation, and functional studies of adult porcine islets of Langerhans.
Topics: Animals; Arginine; Cell Separation; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; DNA; Glucose; Humans; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Nude; Swine | 2002 |
L-arginine supplementation in pigs decreases liver protein turnover and increases hindquarter protein turnover both during and after endotoxemia.
Topics: Acute-Phase Proteins; Animals; Arginine; Blood Gas Analysis; Dietary Supplements; Disease Models, Animal; Endotoxemia; Enteral Nutrition; Female; Hindlimb; Isomerism; Kidney; Liver; Muscle, Skeletal; Phenylalanine; Proteins; Random Allocation; Sepsis; Swine; Viscera | 2002 |
Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Eating; Enzyme Inhibitors; Hypertriglyceridemia; Insulin; Lipid Metabolism; Lipids; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Obesity; Postprandial Period; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Species Specificity; Time | 2002 |
Differential effects of selective and non-selective NOS inhibition on renal arginine and protein metabolism during endotoxemia in rats.
Topics: Animals; Arginine; Disease Models, Animal; Endotoxemia; Enzyme Inhibitors; Isothiuronium; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Protein Biosynthesis; Proteins; Random Allocation; Rats; Rats, Wistar; Sepsis; Specific Pathogen-Free Organisms | 2002 |
Evidence for the involvement of L-citrulline but not nitric oxide in the proconvulsant action of the precursor L-arginine on picrotoxin-induced convulsions in rats.
Topics: Animals; Arginine; Citrulline; Disease Models, Animal; Epilepsy; Male; Nitric Oxide; Rats; Rats, Wistar | 2002 |
[Characteristics of the phlogistic action of melittin, its C-terminal fragment and some basic peptides in the rat paw (author's transl)].
Topics: Animals; Arginine; Cromolyn Sodium; Disease Models, Animal; Hindlimb; Histamine Release; Inflammation; Irritants; Lysine; Male; Melitten; Oligopeptides; Peptide Fragments; Rats; Venoms | 1975 |
Glucagon, insulin, and glucose relationships in a porcine experimental burn model.
Topics: Amino Acids; Animals; Arginine; Blood Glucose; Burns; Disease Models, Animal; Fatty Acids, Nonesterified; Glucagon; Humans; Insulin; Insulin Secretion; Ketones; Resuscitation; Sodium Chloride; Splenectomy; Swine | 1978 |
Long-term function of isotransplanted islets of Langerhans in the diabetic rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus; Diazoxide; Disease Models, Animal; Glycosuria; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Portal Vein; Rats; Sulfonylurea Compounds; Time Factors; Transplantation, Isogeneic | 1976 |
Altered insulin and glucagon secretion in treated genetic hyperlipemia: a mechanism of theraphy?
Topics: Animals; Arginine; Blood Glucose; Disease Models, Animal; Glucagon; Glycolates; Halofenate; Hyperglycemia; Hyperlipidemias; Insulin; Rats; Rats, Inbred Strains | 1976 |
Inhibition of nitric oxide synthesis improves survival in a murine peritonitis model of sepsis that is not cured by antibiotics alone.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cilastatin; Cilastatin, Imipenem Drug Combination; Disease Models, Animal; Drug Combinations; Drug Therapy, Combination; Escherichia coli Infections; Imipenem; Male; Mice; Nitric Oxide Synthase; omega-N-Methylarginine; Peritonitis | 1992 |
Structural and functional correlates of a mutation in the malignant hyperthermia-susceptible pig ryanodine receptor.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Calcium Channels; Cysteine; Disease Models, Animal; Malignant Hyperthermia; Molecular Sequence Data; Mutation; Peptide Mapping; Receptors, Cholinergic; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Structure-Activity Relationship; Swine | 1992 |
The neuroprotective effect of a nitric oxide inhibitor in a rat model of focal cerebral ischaemia.
Topics: Amino Acid Oxidoreductases; Anesthesia; Animals; Arginine; Blood Pressure; Brain Ischemia; Disease Models, Animal; Male; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Inbred Strains | 1992 |
Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia.
Topics: Acute Disease; Animals; Arginine; Bacteremia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Inflammation; Lipopolysaccharides; Liver Diseases; Liver Function Tests; Mice; Mice, Inbred BALB C; Nitric Oxide; omega-N-Methylarginine | 1992 |
Synergistic antithrombotic properties of G4120, a RGD-containing synthetic peptide, and argatroban, a synthetic thrombin inhibitor, in a hamster femoral vein platelet-rich thrombosis model.
Topics: Animals; Antithrombins; Arginine; Aspirin; Blood Coagulation; Cricetinae; Disease Models, Animal; Drug Synergism; Femoral Vein; Fibrinolytic Agents; Hemostasis; Heparin; Injections, Intravenous; Male; Peptides, Cyclic; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Count; Sulfonamides; Sulfoxides; Thrombosis | 1992 |
Inhibition of nitric oxide synthesis does not reduce infarct volume in a rat model of focal cerebral ischaemia.
Topics: Animals; Arginine; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain Ischemia; Cell Death; Cerebral Arteries; Cerebral Infarction; Disease Models, Animal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley | 1992 |
Cardiovascular actions of NG-methyl-L-arginine are abolished in a canine shock model using high-dose endotoxin.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Disease Models, Animal; Dogs; Endotoxins; Escherichia coli; Heart; Hypotension; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Shock; Vascular Resistance; Vasoconstriction | 1992 |
Arginine synthesis by the proximal convoluted tubule in rats with chronic renal failure.
Topics: Animals; Arginine; Disease Models, Animal; Hypertrophy; In Vitro Techniques; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; Rats; Rats, Sprague-Dawley; Reference Values | 1992 |
Markedly reduced beta-cell function does not result in insulin resistance in islet autografted dogs.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Female; Glucagon; Insulin; Insulin Resistance; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Pancreatectomy; Transplantation, Autologous | 1992 |
Protective and pathological roles of nitric oxide in endotoxin shock.
Topics: Animals; Arginine; Blood Pressure; Dexamethasone; Disease Models, Animal; Heart Rate; Male; Nitric Oxide; omega-N-Methylarginine; Penicillamine; Rabbits; Regional Blood Flow; S-Nitroso-N-Acetylpenicillamine; Shock, Septic | 1992 |
Interactions of ibuprofen with influenza infection and hyperammonemia in an animal model of Reye's syndrome.
Topics: Alanine Transaminase; Ammonia; Animals; Arginine; Aspartate Aminotransferases; Diet; Disease Models, Animal; Ferrets; Ibuprofen; Liver; Male; Orthomyxoviridae Infections; Reye Syndrome | 1992 |
Endothelium-derived relaxing factor inhibits constrictor responses of large cerebral arteries to serotonin.
Topics: Animals; Arginine; Blood Pressure; Brain Ischemia; Cerebral Arteries; Disease Models, Animal; Homeostasis; Nitric Oxide; Nitroarginine; Rabbits; Regional Blood Flow; Serotonin; Serotonin Antagonists; Vasoconstriction | 1992 |
L-arginine, the precursor of nitric oxide, abolishes the effect of estrogens on bleeding time in experimental uremia.
Topics: Animals; Arginine; Bleeding Time; Cortodoxone; Dexamethasone; Disease Models, Animal; Estrogen Antagonists; Estrogens, Conjugated (USP); Male; Nitric Oxide; Rats; Rats, Inbred Strains; Uremia | 1991 |
Depletion of dietary arginine inhibits growth of metastatic tumor.
Topics: Adenocarcinoma; Animals; Arginine; Colonic Neoplasms; Diet; Disease Models, Animal; In Vitro Techniques; Liver Neoplasms; Mice; Mice, Inbred BALB C; Tumor Cells, Cultured | 1991 |
Role of nitric oxide in renal medullary oxygenation. Studies in isolated and intact rat kidneys.
Topics: Acute Kidney Injury; Animals; Arginine; Disease Models, Animal; Hypoxia; In Vitro Techniques; Kidney Medulla; Nitric Oxide; omega-N-Methylarginine; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Vasodilation | 1991 |
Comparison of the enteroinsular axis in two strains of obese rat, the fatty Zucker and the JCR:LA-corpulent.
Topics: Administration, Oral; Animals; Arginine; Disease Models, Animal; Gastric Inhibitory Polypeptide; Glucose; Glucose Tolerance Test; Hyperinsulinism; Immunohistochemistry; Insulin; Insulin Resistance; Islets of Langerhans; Male; Obesity; Organ Culture Techniques; Rats; Rats, Zucker | 1991 |
Prevention of diabetes mellitus in BB rats by neonatal stimulation of beta cells.
Topics: Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Glucagon; Glucose; Islets of Langerhans; Rats; Rats, Inbred BB; Time Factors | 1990 |
The effect of heparin on multiple organ failure and disseminated intravascular coagulation in a sepsis model.
Topics: Animals; Antithrombins; Arginine; Blood Coagulation; Disease Models, Animal; Disseminated Intravascular Coagulation; Heparin; Infections; Male; Multiple Organ Failure; Pipecolic Acids; Rabbits; Sulfonamides | 1990 |
Prevention of reocclusion by MCI-9038, a thrombin inhibitor, following t-PA-induced thrombolysis in a canine model of femoral arterial thrombosis.
Topics: Animals; Arginine; Arterial Occlusive Diseases; Disease Models, Animal; Dogs; Femoral Artery; Hemodynamics; Male; Pipecolic Acids; Recurrence; Regional Blood Flow; Sulfonamides; Thrombin; Thrombin Time; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1990 |
Vitamin B12 neuropathy is not due to failure to methylate myelin basic protein.
Topics: Animals; Arginine; Brain Diseases; Chiroptera; Cycloleucine; Disease Models, Animal; Liver; Methylation; Myelin Basic Protein; Rats; Rats, Inbred Strains; Vitamin B 12; Vitamin B 12 Deficiency | 1986 |
Role of thrombin and thromboxane A2 in reocclusion following coronary thrombolysis with tissue-type plasminogen activator.
Topics: Animals; Antithrombins; Arginine; Coronary Disease; Coronary Thrombosis; Disease Models, Animal; Dogs; Phospholipases; Phospholipases A; Pipecolic Acids; Platelet Aggregation; Reperfusion; Sulfonamides; Thrombin; Tissue Plasminogen Activator | 1989 |
Antithrombotic effects of three thrombin inhibitors in a rat model of laser-induced thrombosis.
Topics: Animals; Antithrombins; Arginine; Disease Models, Animal; Hirudins; Humans; Injections, Intravenous; Lasers; Light Coagulation; Pipecolic Acids; Rats; Rats, Inbred Strains; Sulfonamides; Thrombosis | 1989 |
Arginine deficiency, hyperammonemia and Reye's syndrome in ferrets.
Topics: Ammonia; Animals; Animals, Laboratory; Arginine; Carnivora; Disease Models, Animal; Ferrets; Influenza B virus; Male; Orthomyxoviridae Infections; Reye Syndrome | 1985 |
Reversible impairment of glucose-induced insulin secretion in SHR/N-cp rats. Genetic model of type II diabetes.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Disease Models, Animal; Fasting; Female; Genetic Carrier Screening; Genotype; Insulin; Insulin Secretion; Male; Obesity; Pancreas; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Sucrose; Time Factors | 1988 |
Studies on therapy of metabolic alkalosis during experimental uremia. Influences of arginine-hydrochloride on the intra- and extracellular acid-base status of the rat.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Alkalosis; Animals; Arginine; Blood Gas Analysis; Body Fluid Compartments; Disease Models, Animal; Hydrogen-Ion Concentration; Male; Nephrectomy; Rats; Rats, Inbred Strains; Uremia | 1986 |
The ferret as a model for inner ear research.
Topics: Animals; Animals, Laboratory; Arginine; Aspirin; Carnivora; Disease Models, Animal; Ear, Inner; Ferrets; Influenza B virus; Reye Syndrome | 1985 |
Inhibition of bile flow by intravenous arginine hydrochloride.
Topics: Animals; Arginine; Bile; Bile Acids and Salts; Biliary Fistula; Blood Glucose; Cholestasis; Cholesterol; Chronic Disease; Disease Models, Animal; Dogs; Female; Glucagon; Infusions, Parenteral; Phospholipids | 1985 |
The diabetic Chinese hamster: in vitro insulin and glucagon release; the ""chemical diabetic";; and the effect of diet on ketonuria.
Topics: Animals; Arginine; Cricetinae; Diabetes Mellitus; Diabetic Ketoacidosis; Disease Models, Animal; Female; Glucagon; Glucose; Glucose Tolerance Test; Glycosuria; Immunoassay; Insulin; Insulin Secretion; Male; Pancreas; Theophylline | 1974 |
Evidence for decreased sensitivity to glucose of isolated islets from spiny mice. (Acomys cahirinus).
Topics: Animals; Antigens; Arginine; Cyclic AMP; Cytochalasin B; Diabetes Mellitus; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Iodine Radioisotopes; Islets of Langerhans; Male; Mice; Obesity; Radioimmunoassay; Rats; Secretory Rate; Theophylline; Time Factors; Vincristine | 1974 |
Intestinal absorption in experimental Salmonella enterocolitis in mice.
Topics: Animals; Arginine; Body Fluids; Body Weight; Diet; Disease Models, Animal; Enterocolitis, Pseudomembranous; Female; Galactose; Gastrointestinal Motility; Glucose; Histidine; Ileum; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Male; Mice; Morphine; Organ Size; Proteins; Salmonella enteritidis; Salmonella Infections; Serous Membrane | 1972 |
Relationship between elastolytic acitivity and experimental emphysema-induced properties of papain preparations.
Topics: Alanine; Animals; Arginine; Benzoates; Butanols; Cricetinae; Disease Models, Animal; Elastic Tissue; Elastin; Esters; Ethanol; Injections; Lung; Nitrophenols; Papain; Pulmonary Emphysema; Spectrometry, Fluorescence; Trachea | 1974 |
Studies of immunoreactive insulin secretion in NZO mice in vivo.
Topics: Aminophylline; Animals; Antigens; Arginine; Diabetes Mellitus; Disease Models, Animal; Fasting; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Mice; Mice, Inbred Strains; Obesity; Phenytoin; Radioimmunoassay; Secretory Rate | 1974 |
Arginase deficiency in Macaca fascicularis. I. Arginase activity and arginine concentration in erythrocytes and liver.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Arginase; Arginine; Blood Urea Nitrogen; Chromatography, Ion Exchange; Chromatography, Paper; Disease Models, Animal; Erythrocytes; Haplorhini; Liver; Macaca | 1972 |
[Inhibitory effect of histones on the herpesvirus and their chemotherapeutic effect in experimental herpetic keratitis in rabbits].
Topics: Animals; Arginine; Cattle; Cornea; Culture Techniques; Cytopathogenic Effect, Viral; Depression, Chemical; Disease Models, Animal; Herpesviridae; Histones; Keratitis, Dendritic; Lysine; Rabbits; Thymus Gland | 1971 |
Reduced renal arginine-glycine transamidinase activity in myotonic goats and in patients with myotonic muscular dystrophy.
Topics: Acetates; Adult; Aged; Animals; Arginine; Autopsy; Biopsy; Creatine; Disease Models, Animal; Glycine; Goats; Guanine; Humans; Kidney; Male; Muscular Dystrophies; Myotonia; Transferases | 1969 |
[Modification of experimentally induced endogenous hyperammoniemia by amino acids in the rat].
Topics: Amino Acids; Ammonia; Anesthesia, General; Animals; Arginine; Aspartic Acid; Citric Acid Cycle; Depression, Chemical; Disease Models, Animal; Ethyl Ethers; Male; Ornithine; Rats | 1970 |
Teniposide ameliorates bone cancer nociception in rats via the P2X7 receptor.
Topics: Animals; Bone Neoplasms; Carcinoma; Cell Line, Tumor; Cytokines; Disease Models, Animal; Female; Hyperalgesia; Inflammation; Mammary Glands, Animal; Nociception; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Purinergic P2X7; Teniposide | 2018 |
Inhibition of Vascular Calcification.
Topics: 3' Untranslated Regions; Alkaline Phosphatase; Animals; Aorta; Aortic Diseases; Atherosclerosis; Bone Morphogenetic Protein 2; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Disease Models, Animal; Female; Humans; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Signal Transduction; Smad Proteins; Teniposide; Topoisomerase II Inhibitors; Tumor Suppressor Protein p53; Vascular Calcification | 2018 |
Activity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse model.
Topics: Animals; Disease Models, Animal; Fleroxacin; Mice; Mice, Inbred BALB C; Mice, SCID; Pneumocystis; Pneumocystis Infections; Pneumonia, Pneumocystis; Teniposide; Topoisomerase II Inhibitors | 1993 |