arginine has been researched along with Diabetes Mellitus, Type 2 in 530 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 32 (6.04) | 18.7374 |
1990's | 108 (20.38) | 18.2507 |
2000's | 159 (30.00) | 29.6817 |
2010's | 181 (34.15) | 24.3611 |
2020's | 50 (9.43) | 2.80 |
Authors | Studies |
---|---|
Brantley, MA; Calcutt, MW; Harlow, PA; Mitchell, SL; Peters, KS; Rivera, E; Samuels, DC; Warden, C | 1 |
Iwasaki, H; Shichiri, M | 1 |
Bottino, D; Bouskela, E; Costa, G; Shushanof, M | 1 |
Ann-Onda, D; Eizirik, DL; Fynch, S; Galic, S; Herzog, H; Laybutt, DR; Levinger, I; Lin, X; Liu, X; Loh, K; Loudovaris, T; Moreno-Asso, A; Nadarajah, S; Oakhill, JS; Pappas, EG; Scott, JW; Shi, Y; Smith, C; Thomas, HE; Yang, CH | 1 |
Bagnati, M; Basile, M; Bauce, G; Bellomo, G; Dianzani, U; Grigollo, B; Prodam, F; Puricelli, C; Rolla, R | 1 |
Bosch, A; Fromm, MF; Gemeinhardt, A; Gessner, A; Kannenkeril, D; Maas, R; Mayr, A; Schmieder, RE; Staerk, C | 1 |
Krejpcio, Z; Kurek, JM; Szlas, A | 1 |
Avtandilyan, N; Grigoryan, A; Javrushyan, H; Maloyan, A; Nadiryan, E | 1 |
Dorn, GW; Fujimoto, K; Honzawa, N; Ikeuchi, Y; Kikuchi, O; Kitamura, T; Kobayashi, M; Kohno, D; Nishimura, R; Tabei, Y; Utsunomiya, K; Wada, E; Yokota-Hashimoto, H | 1 |
Liu, B; Liu, Y; Niu, WY; Qiao, YC | 1 |
Chen, F; Liao, J; Lu, Q; Niu, C; Wang, H; Wang, S; Yu, Y | 1 |
Dubey, A; Dubey, H; Gulati, K; Ray, A | 1 |
Boaz, M; Buch, A; Ganz, T; Gilad, S; Limor, R; Shefer, G; Stern, N; Wainstein, J | 1 |
D'Alessio, DA; Gray, SM; Hoselton, AL; Krishna, R; Slentz, CA | 1 |
Kooy, A; Lehert, P; Schalkwijk, CG; Stehouwer, CDA; Top, WMC | 1 |
Ahmad, S; Alenazi, F; Alharbi, MS; Ashraf, JM; Hagbani, TA; Khaja, ASS; Qamar, M; Rafi, Z; Saleem, M; Zafar, M | 1 |
Franz, M; Javanmard, SH; Jung, C; Kelishadi, R; Mazrouei, S; Petry, SF; Schulze, PC; Sharifpanah, F | 1 |
Lei, Y; Shi, F; Tian, Q; Zhou, X; Zhu, R | 1 |
Cao, Z; Chen, G; Guo, Y; Hu, X; Li, Y; Liu, X; Xu, Q; Zhang, Y | 1 |
Bagheripour, F; Ghasemi, A; Jeddi, S; Kashfi, K | 1 |
Fang, ZZ; Li, N; Yang, X; Zhang, J; Zhang, Q; Zhang, W; Zheng, J | 1 |
Balint, L; Bob, F; Cretu, OM; Gadalean, F; Glavan, M; Ienciu, S; Jianu, DC; Milas, O; Mogos, M; Petrica, L; Socaciu, AI; Socaciu, C; Suteanu-Simulescu, A; Vlad, A | 1 |
Guo, Z; Li, Y; Liang, Y; Liu, Y; Qu, L; Sun, G; Wang, H; Wang, Y; Zhang, C | 1 |
Chang, B; Hao, Z; Liu, R; Shao, H; Yao, J; Zhao, X | 1 |
Astudillo, M; Balasubramanyam, A; Deen, S; Guffey, D; Hsu, JW; Huang, X; Jahoor, F; Redondo, MJ; Tosur, M; Uysal, S | 1 |
Bouxsein, M; Dawson-Hughes, B; Shea, K | 1 |
Ambrósio, AR; Andrade, VFC; Bavia, L; Borba, VZC; Cavalheiro, DDDS; Chula, DC; da Costa, CRV; Dos Reis, LM; Moreira, CA; Sabbag, FP | 1 |
Fukuda, M; Nagao, Y | 1 |
Mariotti, F | 1 |
Abdel-Rahman, AA; Leffler, KE | 1 |
Derkacz, A; Gać, P; Gocławska, K; Jurdziak, M; Mazur, G; Poręba, M; Poręba, R; Szuba, A; Trzmielewska, E | 1 |
Kaur, G; Kumawat, VS | 1 |
Iqbal, M; Ismat, F; March, M; McPherson, MJ; Onesti, S; Rahman, M; Shah, MA; Shehzad, A; Ullah, R | 1 |
Bhattacharya, N; Ghanate, A; Kannan, S; Kuppan, G; Manickam, N; Mohan, V; Panchagnula, V; Pandey, GK; Parmar, D; Prabu, P; Pramodkumar, TA; Ragi, NC; Sripadi, P; Vadivel, S | 1 |
Abdollahi, S; Clark, CCT; Fallahzadeh, H; Karimi-Nazari, E; Mozaffari-Khosravi, H; Rahmanian, M; Salehi-Abargouei, A; Tabatabaie, M | 1 |
Baek, IH; Ha, ES; Hong, SH; Hwang, SJ; Jin Seo, H; Kim, JS; Kim, MS; Lee, S; Park, H | 1 |
Achenbach, SJ; Atkinson, EJ; Bondar, OP; Drake, MT; Eckhardt, BA; Farr, JN; Hines, JM; Khosla, S; O'Grady, KL; Singh, RJ; Thicke, BS; Tweed, AJ; Volkman, TL | 1 |
Bao, Y; Hu, G; Lu, J; Lu, W; Ma, X; Mo, Y; Shen, Y; Si, Y; Zhang, L; Zhou, J; Zhu, W | 1 |
Abbasi, S; Abd El-Wahab, A; Abdallah, M; Abebe, G; Aca-Aca, G; Adama, S; Adefegha, SA; Adidigue-Ndiome, R; Adiseshaiah, P; Adrario, E; Aghajanian, C; Agnese, W; Ahmad, A; Ahmad, I; Ahmed, MFE; Akcay, OF; Akinmoladun, AC; Akutagawa, T; Alakavuklar, MA; Álava-Rabasa, S; Albaladejo-Florín, MJ; Alexandra, AJE; Alfawares, R; Alferiev, IS; Alghamdi, HS; Ali, I; Allard, B; Allen, JD; Almada, E; Alobaid, A; Alonso, GL; Alqahtani, YS; Alqarawi, W; Alsaleh, H; Alyami, BA; Amaral, BPD; Amaro, JT; Amin, SAW; Amodio, E; Amoo, ZA; Andia Biraro, I; Angiolella, L; Anheyer, D; Anlay, DZ; Annex, BH; Antonio-Aguirre, B; Apple, S; Arbuznikov, AV; Arinsoy, T; Armstrong, DK; Ash, S; Aslam, M; Asrie, F; Astur, DC; Atzrodt, J; Au, DW; Aucoin, M; Auerbach, EJ; Azarian, S; Ba, D; Bai, Z; Baisch, PRM; Balkissou, AD; Baltzopoulos, V; Banaszewski, M; Banerjee, S; Bao, Y; Baradwan, A; Barandika, JF; Barger, PM; Barion, MRL; Barrett, CD; Basudan, AM; Baur, LE; Baz-Rodríguez, SA; Beamer, P; Beaulant, A; Becker, DF; Beckers, C; Bedel, J; Bedlack, R; Bermúdez de Castro, JM; Berry, JD; Berthier, C; Bhattacharya, D; Biadgo, B; Bianco, G; Bianco, M; Bibi, S; Bigliardi, AP; Billheimer, D; Birnie, DH; Biswas, K; Blair, HC; Bognetti, P; Bolan, PJ; Bolla, JR; Bolze, A; Bonnaillie, P; Borlimi, R; Bórquez, J; Bottari, NB; Boulleys-Nana, JR; Brighetti, G; Brodeur, GM; Budnyak, T; Budnyk, S; Bukirwa, VD; Bulman, DM; Burm, R; Busman-Sahay, K; Butcher, TW; Cai, C; Cai, H; Cai, L; Cairati, M; Calvano, CD; Camacho-Ordóñez, A; Camela, E; Cameron, T; Campbell, BS; Cansian, RL; Cao, Y; Caporale, AS; Carciofi, AC; Cardozo, V; Carè, J; Carlos, AF; Carozza, R; Carroll, CJW; Carsetti, A; Carubelli, V; Casarotta, E; Casas, M; Caselli, G; Castillo-Lora, J; Cataldi, TRI; Cavalcante, ELB; Cavaleiro, A; Cayci, Z; Cebrián-Tarancón, C; Cedrone, E; Cella, D; Cereda, C; Ceretti, A; Ceroni, M; Cha, YH; Chai, X; Chang, EF; Chang, TS; Chanteux, H; Chao, M; Chaplin, BP; Chaturvedi, S; Chaturvedi, V; Chaudhary, DK; Chen, A; Chen, C; Chen, HY; Chen, J; Chen, JJ; Chen, K; Chen, L; Chen, Q; Chen, R; Chen, SY; Chen, TY; Chen, WM; Chen, X; Chen, Y; Cheng, G; Cheng, GJ; Cheng, J; Cheng, YH; Cheon, HG; Chew, KW; Chhoker, S; Chiu, WN; Choi, ES; Choi, MJ; Choi, SD; Chokshi, S; Chorny, M; Chu, KI; Chu, WJ; Church, AL; Cirrincione, A; Clamp, AR; Cleff, MB; Cohen, M; Coleman, RL; Collins, SL; Colombo, N; Conduit, N; Cong, WL; Connelly, MA; Connor, J; Cooley, K; Correa Ramos Leal, I; Cose, S; Costantino, C; Cottrell, M; Cui, L; Cundall, J; Cutaia, C; Cutler, CW; Cuypers, ML; da Silva Júnior, FMR; Dahal, RH; Damiani, E; Damtie, D; Dan-Li, W; Dang, Z; Dasa, SSK; Davin, A; Davis, DR; de Andrade, CM; de Jong, PL; de Oliveira, D; de Paula Dorigam, JC; Dean, A; Deepa, M; Delatour, C; Dell'Aiera, S; Delley, MF; den Boer, RB; Deng, L; Deng, Q; Depner, RM; Derdau, V; Derici, U; DeSantis, AJ; Desmarini, D; Diffo-Sonkoue, L; Divizia, M; Djenabou, A; Djordjevic, JT; Dobrovolskaia, MA; Domizi, R; Donati, A; Dong, Y; Dos Santos, M; Dos Santos, MP; Douglas, RG; Duarte, PF; Dullaart, RPF; Duscha, BD; Edwards, LA; Edwards, TE; Eichenwald, EC; El-Baba, TJ; Elashiry, M; Elashiry, MM; Elashry, SH; Elliott, A; Elsayed, R; Emerson, MS; Emmanuel, YO; Emory, TH; Endale-Mangamba, LM; Enten, GA; Estefanía-Fernández, K; Estes, JD; Estrada-Mena, FJ; Evans, S; Ezra, L; Faria de, RO; Farraj, AK; Favre, C; Feng, B; Feng, J; Feng, L; Feng, W; Feng, X; Feng, Z; Fernandes, CLF; Fernández-Cuadros, ME; Fernie, AR; Ferrari, D; Florindo, PR; Fong, PC; Fontes, EPB; Fontinha, D; Fornari, VJ; Fox, NP; Fu, Q; Fujitaka, Y; Fukuhara, K; Fumeaux, T; Fuqua, C; Fustinoni, S; Gabbanelli, V; Gaikwad, S; Gall, ET; Galli, A; Gancedo, MA; Gandhi, MM; Gao, D; Gao, K; Gao, M; Gao, Q; Gao, X; Gao, Y; Gaponenko, V; Garber, A; Garcia, EM; García-Campos, C; García-Donas, J; García-Pérez, AL; Gasparri, F; Ge, C; Ge, D; Ge, JB; Ge, X; George, I; George, LA; Germani, G; Ghassemi Tabrizi, S; Gibon, Y; Gillent, E; Gillies, RS; Gilmour, MI; Goble, S; Goh, JC; Goiri, F; Goldfinger, LE; Golian, M; Gómez, MA; Gonçalves, J; Góngora-García, OR; Gonul, I; González, MA; Govers, TM; Grant, PC; Gray, EH; Gray, JE; Green, MS; Greenwald, I; Gregory, MJ; Gretzke, D; Griffin-Nolan, RJ; Griffith, DC; Gruppen, EG; Guaita, A; Guan, P; Guan, X; Guerci, P; Guerrero, DT; Guo, M; Guo, P; Guo, R; Guo, X; Gupta, J; Guz, G; Hajizadeh, N; Hamada, H; Haman-Wabi, AB; Han, TT; Hannan, N; Hao, S; Harjola, VP; Harmon, M; Hartmann, MSM; Hartwig, JF; Hasani, M; Hawthorne, WJ; Haykal-Coates, N; Hazari, MS; He, DL; He, P; He, SG; Héau, C; Hebbar Kannur, K; Helvaci, O; Heuberger, DM; Hidalgo, F; Hilty, MP; Hirata, K; Hirsch, A; Hoffman, AM; Hoffmann, JF; Holloway, RW; Holmes, RK; Hong, S; Hongisto, M; Hopf, NB; Hörlein, R; Hoshino, N; Hou, Y; Hoven, NF; Hsieh, YY; Hsu, CT; Hu, CW; Hu, JH; Hu, MY; Hu, Y; Hu, Z; Huang, C; Huang, D; Huang, DQ; Huang, L; Huang, Q; Huang, R; Huang, S; Huang, SC; Huang, W; Huang, Y; Huffman, KM; Hung, CH; Hung, CT; Huurman, R; Hwang, SM; Hyun, S; Ibrahim, AM; Iddi-Faical, A; Immordino, P; Isla, MI; Jacquemond, V; Jacques, T; Jankowska, E; Jansen, JA; Jäntti, T; Jaque-Fernandez, F; Jarvis, GA; Jatt, LP; Jeon, JW; Jeong, SH; Jhunjhunwala, R; Ji, F; Jia, X; Jia, Y; Jian-Bo, Z; Jiang, GD; Jiang, L; Jiang, W; Jiang, WD; Jiang, Z; Jiménez-Hoyos, CA; Jin, S; Jobling, MG; John, CM; John, T; Johnson, CB; Jones, KI; Jones, WS; Joseph, OO; Ju, C; Judeinstein, P; Junges, A; Junnarkar, M; Jurkko, R; Kaleka, CC; Kamath, AV; Kang, X; Kantsadi, AL; Kapoor, M; Karim, Z; Kashuba, ADM; Kassa, E; Kasztura, M; Kataja, A; Katoh, T; Kaufman, JS; Kaupp, M; Kehinde, O; Kehrenberg, C; Kemper, N; Kerr, CW; Khan, AU; Khan, MF; Khan, ZUH; Khojasteh, SC; Kilburn, S; Kim, CG; Kim, DU; Kim, DY; Kim, HJ; Kim, J; Kim, OH; Kim, YH; King, C; Klein, A; Klingler, L; Knapp, AK; Ko, TK; Kodavanti, UP; Kolla, V; Kong, L; Kong, RY; Kong, X; Kore, S; Kortz, U; Korucu, B; Kovacs, A; Krahnert, I; Kraus, WE; Kuang, SY; Kuehn-Hajder, JE; Kurz, M; Kuśtrowski, P; Kwak, YD; Kyttaris, VC; Laga, SM; Laguerre, A; Laloo, A; Langaro, MC; Langham, MC; Lao, X; Larocca, MC; Lassus, J; Lattimer, TA; Lazar, S; Le, MH; Leal, DB; Leal, M; Leary, A; Ledermann, JA; Lee, JF; Lee, MV; Lee, NH; Leeds, CM; Leeds, JS; Lefrandt, JD; Leicht, AS; Leonard, M; Lev, S; Levy, K; Li, B; Li, C; Li, CM; Li, DH; Li, H; Li, J; Li, L; Li, LJ; Li, N; Li, P; Li, T; Li, X; Li, XH; Li, XQ; Li, XX; Li, Y; Li, Z; Li, ZY; Liao, YF; Lin, CC; Lin, MH; Lin, Y; Ling, Y; Links, TP; Lira-Romero, E; Liu, C; Liu, D; Liu, H; Liu, J; Liu, L; Liu, LP; Liu, M; Liu, T; Liu, W; Liu, X; Liu, XH; Liu, Y; Liuwantara, D; Ljumanovic, N; Lobo, L; Lokhande, K; Lopes, A; Lopes, RMRM; López-Gutiérrez, JC; López-Muñoz, MJ; López-Santamaría, M; Lorenzo, C; Lorusso, D; Losito, I; Lu, C; Lu, H; Lu, HZ; Lu, SH; Lu, SN; Lu, Y; Lu, ZY; Luboga, F; Luo, JJ; Luo, KL; Luo, Y; Lutomski, CA; Lv, W; M Piedade, MF; Ma, J; Ma, JQ; Ma, JX; Ma, N; Ma, P; Ma, S; Maciel, M; Madureira, M; Maganaris, C; Maginn, EJ; Mahnashi, MH; Maierhofer, M; Majetschak, M; Malla, TR; Maloney, L; Mann, DL; Mansuri, A; Marelli, E; Margulis, CJ; Marrella, A; Martin, BL; Martín-Francés, L; Martínez de Pinillos, M; Martínez-Navarro, EM; Martinez-Quintanilla Jimenez, D; Martínez-Velasco, A; Martínez-Villaseñor, L; Martinón-Torres, M; Martins, BA; Massongo, M; Mathew, AP; Mathews, D; Matsui, J; Matsumoto, KI; Mau, T; Maves, RC; Mayclin, SJ; Mayer, JM; Maynard, ND; Mayr, T; Mboowa, MG; McEvoy, MP; McIntyre, RC; McKay, JA; McPhail, MJW; McVeigh, AL; Mebazaa, A; Medici, V; Medina, DN; Mehmood, T; Mei-Li, C; Melku, M; Meloncelli, S; Mendes, GC; Mendoza-Velásquez, C; Mercadante, R; Mercado, MI; Merenda, MEZ; Meunier, J; Mi, SL; Michels, M; Mijatovic, V; Mikhailov, V; Milheiro, SA; Miller, DC; Ming, F; Mitsuishi, M; Miyashita, T; Mo, J; Mo, S; Modesto-Mata, M; Moeller, S; Monte, A; Monteiro, L; Montomoli, J; Moore, EE; Moore, HB; Moore, PK; Mor, MK; Moratalla-López, N; Moratilla Lapeña, L; Moreira, R; Moreno, MA; Mörk, AC; Morton, M; Mosier, JM; Mou, LH; Mougharbel, AS; Muccillo-Baisch, AL; Muñoz-Serrano, AJ; Mustafa, B; Nair, GM; Nakanishi, I; Nakanjako, D; Naraparaju, K; Nawani, N; Neffati, R; Neil, EC; Neilipovitz, D; Neira-Borrajo, I; Nelson, MT; Nery, PB; Nese, M; Nguyen, F; Nguyen, MH; Niazy, AA; Nicolaï, J; Nogueira, F; Norbäck, D; Novaretti, JV; O'Donnell, T; O'Dowd, A; O'Malley, DM; Oaknin, A; Ogata, K; Ohkubo, K; Ojha, M; Olaleye, MT; Olawande, B; Olomo, EJ; Ong, EWY; Ono, A; Onwumere, J; Ortiz Bibriesca, DM; Ou, X; Oza, AM; Ozturk, K; Özütemiz, C; Palacio-Pastrana, C; Palaparthi, A; Palevsky, PM; Pan, K; Pantanetti, S; Papachristou, DJ; Pariani, A; Parikh, CR; Parissis, J; Paroul, N; Parry, S; Patel, N; Patel, SM; Patel, VC; Pawar, S; Pefura-Yone, EW; Peixoto Andrade, BCO; Pelepenko, LE; Peña-Lora, D; Peng, S; Pérez-Moro, OS; Perez-Ortiz, AC; Perry, LM; Peter, CM; Phillips, NJ; Phillips, P; Pia Tek, J; Piner, LW; Pinto, EA; Pinto, SN; Piyachaturawat, P; Poka-Mayap, V; Polledri, E; Poloni, TE; Ponessa, G; Poole, ST; Post, AK; Potter, TM; Pressly, BB; Prouty, MG; Prudêncio, M; Pulkki, K; Pupier, C; Qian, H; Qian, ZP; Qiu, Y; Qu, G; Rahimi, S; Rahman, AU; Ramadan, H; Ramanna, S; Ramirez, I; Randolph, GJ; Rasheed, A; Rault, J; Raviprakash, V; Reale, E; Redpath, C; Rema, V; Remucal, CK; Remy, D; Ren, T; Ribeiro, LB; Riboli, G; Richards, J; Rieger, V; Rieusset, J; Riva, A; Rivabella Maknis, T; Robbins, JL; Robinson, CV; Roche-Campo, F; Rodriguez, R; Rodríguez-de-Cía, J; Rollenhagen, JE; Rosen, EP; Rub, D; Rubin, N; Rubin, NT; Ruurda, JP; Saad, O; Sabell, T; Saber, SE; Sabet, M; Sadek, MM; Saejio, A; Salinas, RM; Saliu, IO; Sande, D; Sang, D; Sangenito, LS; Santos, ALSD; Sarmiento Caldas, MC; Sassaroli, S; Sassi, V; Sato, J; Sauaia, A; Saunders, K; Saunders, PR; Savarino, SJ; Scambia, G; Scanlon, N; Schetinger, MR; Schinkel, AFL; Schladweiler, MC; Schofield, CJ; Schuepbach, RA; Schulz, J; Schwartz, N; Scorcella, C; Seeley, J; Seemann, F; Seinige, D; Sengoku, T; Seravalli, J; Sgromo, B; Shaheen, MY; Shan, L; Shanmugam, S; Shao, H; Sharma, S; Shaw, KJ; Shen, BQ; Shen, CH; Shen, P; Shen, S; Shen, Y; Shen, Z; Shi, J; Shi-Li, L; Shimoda, K; Shoji, Y; Shun, C; Silva, MA; Silva-Cardoso, J; Simas, NK; Simirgiotis, MJ; Sincock, SA; Singh, MP; Sionis, A; Siu, J; Sivieri, EM; Sjerps, MJ; Skoczen, SL; Slabon, A; Slette, IJ; Smith, MD; Smith, S; Smith, TG; Snapp, KS; Snow, SJ; Soares, MCF; Soberman, D; Solares, MD; Soliman, I; Song, J; Sorooshian, A; Sorrell, TC; Spinar, J; Staudt, A; Steinhart, C; Stern, ST; Stevens, DM; Stiers, KM; Stimming, U; Su, YG; Subbian, V; Suga, H; Sukhija-Cohen, A; Suksamrarn, A; Suksen, K; Sun, J; Sun, M; Sun, P; Sun, W; Sun, XF; Sun, Y; Sundell, J; Susan, LF; Sutjarit, N; Swamy, KV; Swisher, EM; Sykes, C; Takahashi, JA; Talmor, DS; Tan, B; Tan, ZK; Tang, L; Tang, S; Tanner, JJ; Tanwar, M; Tarazi, Z; Tarvasmäki, T; Tay, FR; Teketel, A; Temitayo, GI; Thersleff, T; Thiessen Philbrook, H; Thompson, LC; Thongon, N; Tian, B; Tian, F; Tian, Q; Timothy, AT; Tingle, MD; Titze, IR; Tolppanen, H; Tong, W; Toyoda, H; Tronconi, L; Tseng, CH; Tu, H; Tu, YJ; Tung, SY; Turpault, S; Tuynman, JB; Uemoto, AT; Ugurlu, M; Ullah, S; Underwood, RS; Ungell, AL; Usandizaga-Elio, I; Vakonakis, I; van Boxel, GI; van den Beucken, JJJP; van der Boom, T; van Slegtenhorst, MA; Vanni, JR; Vaquera, A; Vasconcellos, RS; Velayos, M; Vena, R; Ventura, G; Verso, MG; Vincent, RP; Vitale, F; Vitali, S; Vlek, SL; Vleugels, MPH; Volkmann, N; Vukelic, M; Wagner Mackenzie, B; Wairagala, P; Waller, SB; Wan, J; Wan, MT; Wan, Y; Wang, CC; Wang, H; Wang, J; Wang, JF; Wang, K; Wang, L; Wang, M; Wang, S; Wang, WM; Wang, X; Wang, Y; Wang, YD; Wang, YF; Wang, Z; Wang, ZG; Warriner, K; Weberpals, JI; Weerachayaphorn, J; Wehrli, FW; Wei, J; Wei, KL; Weinheimer, CJ; Weisbord, SD; Wen, S; Wendel Garcia, PD; Williams, JW; Williams, R; Winkler, C; Wirman, AP; Wong, S; Woods, CM; Wu, B; Wu, C; Wu, F; Wu, P; Wu, S; Wu, Y; Wu, YN; Wu, ZH; Wurtzel, JGT; Xia, L; Xia, Z; Xia, ZZ; Xiao, H; Xie, C; Xin, ZM; Xing, Y; Xing, Z; Xu, S; Xu, SB; Xu, T; Xu, X; Xu, Y; Xue, L; Xun, J; Yaffe, MB; Yalew, A; Yamamoto, S; Yan, D; Yan, H; Yan, S; Yan, X; Yang, AD; Yang, E; Yang, H; Yang, J; Yang, JL; Yang, K; Yang, M; Yang, P; Yang, Q; Yang, S; Yang, W; Yang, X; Yang, Y; Yao, JC; Yao, WL; Yao, Y; Yaqub, TB; Ye, J; Ye, W; Yen, CW; Yeter, HH; Yin, C; Yip, V; Yong-Yi, J; Yu, HJ; Yu, MF; Yu, S; Yu, W; Yu, WW; Yu, X; Yuan, P; Yuan, Q; Yue, XY; Zaia, AA; Zakhary, SY; Zalwango, F; Zamalloa, A; Zamparo, P; Zampini, IC; Zani, JL; Zeitoun, R; Zeng, N; Zenteno, JC; Zepeda-Palacio, C; Zhai, C; Zhang, B; Zhang, G; Zhang, J; Zhang, K; Zhang, Q; Zhang, R; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, B; Zhao, D; Zhao, G; Zhao, H; Zhao, Q; Zhao, R; Zhao, S; Zhao, T; Zhao, X; Zhao, XA; Zhao, Y; Zhao, Z; Zheng, Z; Zhi-Min, G; Zhou, CL; Zhou, HD; Zhou, J; Zhou, W; Zhou, XQ; Zhou, Z; Zhu, C; Zhu, H; Zhu, L; Zhu, Y; Zitzmann, N; Zou, L; Zou, Y | 1 |
Alizadeh, M; Esmaeili, F; Kheirouri, S; Maleki, V | 1 |
Engel, H; Gazyakan, E; Germann, G; Hirche, C; Reichenberger, MA; Urbach, O | 1 |
Cho, J; Enya, M; Handa, H; Horikawa, Y; Imai, T; Imai, Y; Takeda, J | 1 |
Kulwas, A; Rość, D; Wieczór, AM; Wieczór, R | 1 |
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Asano, T; Inoue, H; Kizuki, N; Oka, Y; Oota, Y; Tanizawa, Y; Tsukuda, K; Ueda, K | 1 |
Amann, G; Aufricht, C; Höger, H; Kitzmüller, E; Lubec, B | 1 |
Akanuma, Y; Kadowaki, T; Katakura, T; Kim-Motoyama, H; Ohashi, Y; Shuldiner, AR; Yamada, N; Yamaguchi, T; Yasuda, K; Yazaki, Y | 1 |
Bodkin, NL; Hansen, BC; Lowe, A; Shuldiner, AR; Silver, K; Walston, J; Yang, Y | 1 |
Blanco, MC; Camejo, M; Contreras, I; Giansante, E; Gonzalez, F; Lopez, T; Martinez, N; Molina, M; Postalian, S; Reiser, KM; Sanchez, MR; Suarez, N | 1 |
Heikkinen, S; Kekäläinen, P; Kuopusjärvi, J; Kuusisto, J; Laakso, M; Pihlajamäki, J; Rissanen, J; Sipiläinen, R; Vanhala, M | 1 |
Bahadori, B; Dittrich, P; Graier, WF; Hussain, MA; Toplak, H; Wallner, S; Wascher, TC | 1 |
Arii, K; Hashimoto, K; Ikeda, Y; Ito, H; Nakauchi, Y; Suehiro, T; Yamamoto, M | 1 |
Barrow, BA; Levy, JC; Manley, SE; Rachman, J; Turner, RC | 1 |
Acampora, R; Coppola, L; D'Onofrio, F; Giugliano, D; Marfella, R; Nappo, F; Verrazzo, G; Ziccardi, P | 1 |
Halban, PA; Kahn, SE | 1 |
Horie, K; Kurokawa, K; Maeda, K; Miyata, S; Miyata, T; Monnier, VM; Sakai, H; Sugiyama, S; van Ypersole de Strihou, C; Witztum, JL | 1 |
Attali, JR; Ledoux, S; Nitenberg, A; Valensi, P | 1 |
Biery, AJ; Boyer, BB; Ebbesson, SO; Shuldiner, AR | 1 |
Block, C; Ferguson, K; Fogarty, J; Haas, C; Hampel, N; Ni, Z; Polak, J; Razmjouei, K; Seftel, AD; Vaziri, ND; Wang, RZ | 1 |
Boland, O; Matthews, DR | 1 |
Mitchell, BD; Roth, J; Shuldiner, AR; Silver, K; Sorkin, JD; Stern, MP; Walston, J | 1 |
Strosberg, AD | 1 |
Kahn, SE; Porte, D; Røder, ME; Schwartz, RS | 1 |
Attali, JR; Ledoux, S; Nitenberg, A; Paycha, F; Sachs, R; Valensi, P | 1 |
Ishiguro, N; Ito, T; Iwata, H; Kurokawa, K; Miyata, T; Nangaku, M; Yasuda, Y | 1 |
Broca, C; Gross, R; Hillaire-Buys, D; Manteghetti, M; Masiello, P; Novelli, M; Ribes, G; Roye, M | 1 |
Bailbé, D; Campillo, JE; Portha, B; Saulnier, C; Serradas, P; Tormo, MA | 1 |
Azuma, N; Hosoda, K; Igaki, T; Itoh, H; Masuzaki, H; Matsuoka, N; Miyamoto, Y; Nakao, K; Nishi, S; Nishimura, H; Satoh, N; Shigemoto, M; Suga, J; Tanaka, T; Yamamoto, Y; Yoshimasa, T; Yoshimasa, Y | 1 |
Acampora, R; Coppola, L; D'Onofrio, F; Giugliano, D; Giunta, R; Marfella, R | 1 |
Campbell, LV; Chalkley, SM; Chisholm, DJ; Furler, SM; Kraegen, EW | 1 |
Baron, AD; Shankar, RR; Zhu, JS | 1 |
Baldwin, A; Bell, GI; Bonner-Weir, S; Doyen, A; Froguel, P; Levisetti, M; Ostrega, D; Pick, AJ; Polonsky, KS; Pontoglio, M; Pugh, W; Roe, M; Sreenan, S; Velho, G; Yaniv, M | 1 |
Kogure, A; Kondo, M; Sakane, N; Umekawa, T; Yoshida, T; Yoshioka, K | 1 |
Fukuo, Y; Gotoda, T; Harada, K; Ishibashi, S; Ohashi, K; Osuga, J; Sun, L; Yamada, N; Yazaki, Y | 1 |
Nakanishi, K; Ohta, H; Shima, Y; Tsukada, T | 1 |
Arndt, H; Büettner, R; Cuk, A; Enger, I; Hügl, S; Nusser, J; Palitzsch, KD; Rogler, G; Schäffler, A; Schölmerich, J; Zietz, B | 1 |
Kawashima, S; Kurokawa, K; Maeda, K; Miyata, T; Sugiyama, S; Tanaka, H; Ueda, Y; Van Ypersele de Strihou, C | 1 |
Birnbacher, R; Herkner, K; Kampel, D; Krapfenbauer, K; Lubec, G; Vierhapper, H | 1 |
Baba, T; Nakajima, S; Yajima, Y | 1 |
Kogure, A; Kondo, M; Nakamura, Y; Sakane, N; Takakura, Y; Umekawa, T; Yoshida, T; Yoshioka, K | 1 |
Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J | 1 |
Enderle, MD; Füllhase, J; Häring, HU; Karsch, KR; Koch, M; Kühn, R; Pfohl, M | 1 |
Daimon, M; Eguchi, H; Hirata, A; Igarashi, M; Kato, T; Manaka, H; Ohnuma, H; Ono, Y; Saito, T; Yamaguchi, H | 1 |
Fumelli, P; Mazzanti, L; Moretti, N; Mutus, B; Rabini, RA; Tannous, M; Vignini, A; Zielinski, B | 1 |
Hamaguchi, T; Hanafusa, T; Higashiyama, S; Horikawa, Y; Imagawa, A; Iwahashi, H; Matsuzawa, Y; Miyagawa, J; Miyazaki, J; Nakajima, H; Namba, M; Okita, K; Oue, T; Satoh, T; Yamagata, K; Yamamoto, K; Yamasaki, T; Yang, Q; Yoshiuchi, I | 1 |
Grzeszczak, W; Labuz, B; Lacka, B; Saucha, W; Szydlowska, I; Zukowska-Szczechowska, E; Zychma, MJ | 1 |
Iwamoto, Y; Iwasaki, N; Kanamori, M; Minei, S; Omori, Y; Sanaka, M; Yanagisawa, K | 1 |
Hehmke, B; Kessler, J; Klöting, I; Kohnert, KD | 1 |
Deninger, M; Haist, K; Häring, HU; Koch, M; Maerker, E; Renn, W; Rett, K; Volk, A | 1 |
Emoto, M; Inaba, M; Ishimura, E; Kanda, H; Kawagishi, T; Matsuyoshi, M; Morii, H; Nishizawa, Y; Okuno, Y; Taniwaki, H | 1 |
Clément, K; Fiet, J; Froguel, P; Philippe, J; Pueyo, ME; Robert, JJ; Tappy, L; Timsit, J; Vaxillaire, M; Velho, G | 1 |
Carlsson, A; Groop, L; Sundkvist, G; Tuomi, T | 1 |
Fritsche, A; Hardt, E; Häring, H; Schützenauer, S; Stefan, N; Stumvoll, M | 1 |
Coppola, G; De Angelis, L; Esposito, K; Farzati, B; Giugliano, D; Giunta, R; Marfella, R; Paolisso, G | 1 |
Danielsson, R; Fogarty, JF; Frank, A; Monnier, VM; Sell, DR | 1 |
De Angelis, L; Giugliano, D; Marfella, R; Nappo, F; Paolisso, G; Tagliamonte, MR | 1 |
Baba, T; Nakajima, S | 1 |
Bell, GI; D'Souza, E; Fajans, SS; Herman, WH; Ilag, LL; Tabaei, BP; Zawacki, CM | 1 |
Berglund, L; Bryant, TA; Cannon, PJ; Chen, NT; Di Tullio, MR; Donis, JA; Fard, A; Ginsberg, HN; Homma, S; Ramasamy, R; Sciacca, R; Torres-Tamayo, M; Tuck, CH; Wu, HD | 1 |
Andersen, RE; Beamer, B; Hilfiker, H; Poehlman, E; Roth, J; Seibert, M; Shuldiner, AR; Silver, K; Walston, J | 1 |
Carmo, A; Carvalho, AP; Cunha-Vaz, JG; Lopes, MC | 1 |
Ferlito, S; Gallina, M | 1 |
Bon, MA; Oeveren van-Dybicz, AM; van den Bergh, FA; Vermes, I; Vonkeman, HE | 1 |
Alberti, KG; Galli-Kienle, M; Magni, F; Marchesi, F; Monti, LD; Piatti, PM; Pozza, G; Setola, E; Valsecchi, G | 1 |
Bengtsson, K; Groop, L; Lindblad, U; Melander, O; Orho-Melander, M; Ranstam, J; Råstam, L | 1 |
Carlsson, M; Groop, LC; Hedenbro, J; Orho-Melander, M | 1 |
Barth, C; Ehren, M; Enderle, MD; Hering, S; Koch, M; Pfohl, M | 1 |
Biondi, RM; Cohen, P; Frame, S | 1 |
Fujimoto, D; Hiki, Y; Iijima, K; Irie, S; Kusunoki, H; Maeda, K; Miyata, S; Nakata, M; Odani, H; Yasuda, Y | 1 |
Benatti, U; Bordone, C; Cataldi, L; Giovine, M; Leoncini, G; Pascale, R; Signorello, MG | 1 |
Daimon, M; Eguchi, H; Igarashi, M; Kameda, W; Kato, T; Manaka, H; Ohnuma, H; Oizumi, T; Saitoh, T; Tominaga, M; Yamaguchi, H | 1 |
Fukui, H; Kadowaki, M; Kuramoto, H; Takaki, M; Yoneda, S | 1 |
De Angelis, L; De Lucia, D; Giugliano, D; Giugliano, F; Marfella, MA; Marino, L; Nappo, F; Siniscalchi, M | 1 |
Babaya, N; Hamada, Y; Ikegami, H; Kawaguchi, Y; Nojima, K; Ogihara, T; Shibata, M; Ueda, H; Yamada, K; Yamato, E | 1 |
Abbasi, F; Asagmi, T; Cooke, JP; Lamendola, C; McLaughlin, T; Reaven, GM; Stuehlinger, M; Tsao, PS | 1 |
Shun, I; Sun, L; Yoko, I | 1 |
Camastra, S; Ferrannini, E; Gastaldelli, A; Mari, A; Masoni, A; Natali, A; Sironi, AM; Toschi, E | 1 |
Himeno, M; Ishibashi, T; Maejima, K; Nakano, S; Nishio, M; Uchida, K | 1 |
Adachi, T; Fujimoto, S; Mukai, E; Nunoi, K; Okamoto, Y; Oku, A; Seino, Y; Shihara, N; Suzuki, N; Tamon, A; Tsuda, K; Yasuda, K | 1 |
AvRuskin, TW; Juan, CS | 1 |
Ishimura, N; Nakaya, Y; Takahashi, A; Takishita, E | 1 |
Abbasi, F; Asagami, T; Cooke, JP; Lamendola, C; McLaughlin, T; Reaven, GM; Stuelinger, M; Tsao, PS | 1 |
Cheng, HM; Ho, LT; Jap, TS; Kwok, CF; Lee, KT | 1 |
Borghi, VC; Giannella-Neto, D; Porrelli, RN; Santomauro, AT; Wajchenberg, BL | 1 |
Ceriello, A; D'Onofrio, F; Giugliano, D; Paolisso, G; Saccomanno, F; Torella, R; Varricchio, M | 1 |
Bonnafous, R; Fichaux, F | 1 |
Charbonnel, B; Garnier, JM; Krempf, M; Ranganatan, S; Ritz, P | 1 |
Fukushima, H; Hamaguchi, T; Ichinose, K; Kishikawa, H; Shichiri, M; Shirotani, T; Uehara, M; Wada, S; Yamaguchi, K | 1 |
Gerich, JE; Van der Veen, EA; Van Haeften, TW; Van Maarschalkerweerd, WW | 1 |
Halter, JB; Herman, WH; Ortiz-Alonso, FJ; Perry, TJ; Smith, MJ; Zobel, DL | 1 |
Leahy, JL; Weir, GC | 1 |
Efendic, S; Grill, V; Ostenson, CG | 1 |
Holst, JJ; Jeppesen, J; Madsbad, S; Orskov, C | 1 |
Bailbé, D; Blondel, O; Portha, B; Serradas, P | 1 |
Bailbé, D; Giroix, MH; Goto, Y; Portha, B; Serradas, P; Suzuki, K | 1 |
Beard, JC; Johnston, C; McKnight, B; Porte, D; Ward, WK | 1 |
Doi, K; Morita, S | 1 |
Bonner-Weir, S; Leahy, JL; Weir, GC | 1 |
Alford, FP; Best, JD; Crock, PA; Pestell, RG; Ward, GM | 1 |
Bailbé, D; Portha, B; Serradas, P | 1 |
D'Onofrio, F; Giunta, R; Marrazzo, G; Paolisso, G; Passariello, N; Pizza, G; Sgambato, S; Varricchio, M | 1 |
Kajinuma, H; Miyata, H; Suzuki, K; Suzuki, T | 1 |
Kitada, M; Miura, K; Takeda, N; Yasuda, K | 1 |
Best, JD; Halter, JB; Pfeifer, MA; Porte, D; Ward, WK | 1 |
Bajaj, V; Broadstone, VL; Pfeifer, MA; Samols, E; Stagner, JI | 1 |
Ceriello, A; D'Onofrio, F; Giugliano, D; Lefèbvre, P; Paolisso, G; Salvatore, T | 1 |
Andreone, T; Permutt, MA; Porte, D; Rotwein, P; Ward, WK | 1 |
Boden, G | 1 |
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Hashimoto, N; Horie, H; Iwaoka, H; Kanatsuka, A; Makino, H; Sakurada, M; Yoshida, S | 1 |
Beard, JC; LaCava, EC; Paquette, TL; Porte, D; Wallum, BJ; Ward, WK | 1 |
D'Onofrio, F; Paolisso, G; Passariello, N; Pizza, G; Sgambato, S; Tesauro, P; Torella, R; Varricchio, M | 1 |
Bertelli, R; Cornaglia-Ferraris, P; Knight, RA; Melino, G; Melodia, A; Perezzani, L | 1 |
Jialal, I; Joubert, SM; Naidoo, C | 1 |
Giroix, MH; Kergoat, M; Portha, B | 1 |
Ceriello, A; Consoli, G; D'Onofrio, F; Giugliano, D; Quatraro, A; Torella, R | 1 |
Gefferth, G; Gerò, L; Grósz, A; Halmos, T; Karádi, I; Kollin, E; Simonyi, E; Vargha, P; Winkler, G | 1 |
Dimitriadis, GD; Gerich, JE; Pehling, GB | 1 |
Barclay-White, B; Bennett, PH; Katzeff, HL; Nagulesparan, M; Savage, PJ | 1 |
Abadie, E; Fiet, J; Gauville, C; Passa, P; Tabuteau, F; Villette, JM | 1 |
Beard, JC; Benedetti, TJ; Halter, JB; Johnston, CL; Porte, D; Ward, WK | 1 |
Beard, JC; Halter, JB; Porte, D; Ward, WK | 1 |
Raskin, P | 1 |
Abe, H; Kawamori, R; Kikuchi, M; Shichiri, M; Yamasaki, Y | 1 |
28 review(s) available for arginine and Diabetes Mellitus, Type 2
Article | Year |
---|---|
The Potential of L-Arginine in Prevention and Treatment of Disturbed Carbohydrate and Lipid Metabolism-A Review.
Topics: Arginine; Carbohydrates; Diabetes Mellitus, Type 2; Humans; Lipid Metabolism; Nitric Oxide | 2022 |
Metabolic effects of L-citrulline in type 2 diabetes.
Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Muscle, Skeletal | 2023 |
Arginine supplementation and cardiometabolic risk.
Topics: Arginine; Biological Availability; Cardiometabolic Risk Factors; Diabetes Mellitus, Type 2; Dietary Supplements; Endothelium, Vascular; Humans; Vascular Diseases | 2020 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea | 2022 |
Review of methods for measuring β-cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium.
Topics: Arginine; Biomarkers; Diabetes Mellitus, Type 2; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Models, Biological; Postprandial Period; Research Design | 2018 |
The most effective polymorphisms of paraoxonase-1 gene on enzyme activity and concentration of paraoxonase-1 protein in type 2 diabetes mellitus patients and non-diabetic individuals: A systematic review and meta-analysis.
Topics: Amino Acid Substitution; Arginine; Aryldialkylphosphatase; Diabetes Mellitus, Type 2; Enzyme Activation; Female; Gain of Function Mutation; Genotype; Glutamic Acid; Humans; Leucine; Male; Methionine; Polymorphism, Genetic | 2019 |
A report of 2 new cases of MODY2 and review of the literature: implications in the search for type 2 diabetes drugs.
Topics: Arginine; Child; Codon, Nonsense; Congenital Hyperinsulinism; Diabetes Mellitus, Type 2; Female; Glucokinase; Glucose Tolerance Test; Glutamic Acid; Humans; Hypoglycemic Agents; Infant, Newborn; Mutation; Proline | 2013 |
Nutritional factors in the prevention and management of coronary artery disease and heart failure.
Topics: Alprostadil; Anti-Inflammatory Agents; Arginine; CD59 Antigens; Coronary Artery Disease; Diabetes Mellitus, Type 2; Epoprostenol; Fatty Acids, Essential; Fatty Acids, Unsaturated; Female; Folic Acid; Heart Failure; Humans; Hypertension; Lipoxins; Magnesium; Male; Middle Aged; Nitric Oxide; Nutritional Status; Serum Albumin; Vasodilation; Vitamin B 12; Vitamin B 6 | 2015 |
Association of LEPR Gln223Arg polymorphism with T2DM: A meta-analysis.
Topics: Amino Acid Substitution; Arginine; Diabetes Mellitus, Type 2; Genetic Association Studies; Genetic Predisposition to Disease; Glutamine; Humans; Polymorphism, Single Nucleotide; Receptors, Leptin | 2015 |
[The assessment of bone quality in lifestyle-related diseases].
Topics: Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Diabetes Mellitus, Type 2; Homocysteine; Humans; Hyperhomocysteinemia; Life Style; Lysine; Osteoporosis; Pulmonary Disease, Chronic Obstructive; Renal Insufficiency, Chronic; Risk; Tomography, X-Ray Computed | 2016 |
L-Arginine Modulates Glucose and Lipid Metabolism in Obesity and Diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin Resistance; Lipid Metabolism; Nitric Oxide; Obesity; Signal Transduction | 2017 |
Development and Analysis of Novel Therapeutic Targets to Improve Pancreatic β-Cell Function in Type 2 Diabetes.
Topics: Antioxidants; Apoptosis; Arginine; Catalysis; Cystathionine gamma-Lyase; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Humans; Hydrogen Sulfide; Insulin; Insulin Secretion; Insulin-Secreting Cells; Molecular Targeted Therapy; Nitric Oxide; Nitric Oxide Synthase | 2016 |
An examination of beta-cell function measures and their potential use for estimating beta-cell mass.
Topics: Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Male; Prediabetic State | 2008 |
The emerging role of TRIB3 as a gene affecting human insulin resistance and related clinical outcomes.
Topics: Amino Acid Substitution; Arginine; Cell Cycle Proteins; Cost of Illness; Diabetes Mellitus, Type 2; Genetic Variation; Glutamine; Humans; Incidence; Insulin; Insulin Resistance; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Repressor Proteins; Signal Transduction | 2009 |
Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets.
Topics: Arginine; Asian People; Cation Transport Proteins; Diabetes Mellitus, Type 2; Genotype; Glucagon; Glucose; Glyburide; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Polymorphism, Genetic; Risk; White People; Zinc Transporter 8 | 2010 |
Post-challenge hyperglycaemia, nitric oxide production and endothelial dysfunction: the putative role of asymmetric dimethylarginine (ADMA).
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Glucose; Glucose Tolerance Test; Heart Diseases; Humans; Hyperglycemia; Metabolic Diseases; Nitric Oxide; Oxidative Stress | 2011 |
L-arginine, NO and asymmetrical dimethylarginine in hypertension and type 2 diabetes.
Topics: Animals; Antihypertensive Agents; Arginine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Hypertension; Insulin Resistance; Nitric Oxide; Nitric Oxide Synthase Type III; Prognosis | 2011 |
[Diabetes mellitus and osteoporosis. Predictive candidate markers for fracture risk in diabetic patients].
Topics: Arginine; Diabetes Mellitus, Type 2; Fractures, Bone; Humans; Lysine; Osteoporosis; Risk Factors | 2012 |
Gly972Arg variant in the insulin receptor substrate-1 gene and association with Type 2 diabetes: a meta-analysis of 27 studies.
Topics: Amino Acid Substitution; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Genetic Carrier Screening; Genetic Variation; Glycine; Humans; Insulin Receptor Substrate Proteins; Obesity; Odds Ratio; Phosphoproteins; Racial Groups | 2003 |
[Asymmetrical methylarginine (ADMA) as a cardiovascular risk factor: epidemiological and prospective data].
Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Arteriosclerosis; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cells, Cultured; Child; Coronary Disease; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelial Cells; Enzyme-Linked Immunosorbent Assay; Female; Free Radicals; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Multicenter Studies as Topic; Multivariate Analysis; Nitric Oxide Synthase; Oxidative Stress; Pre-Eclampsia; Pregnancy; Prospective Studies; Rabbits; Regression Analysis; Renal Dialysis; Risk Factors; Stroke | 2004 |
Endothelial cell dysfunction and the vascular complications associated with type 2 diabetes: assessing the health of the endothelium.
Topics: Arginine; Biological Factors; Biomarkers; C-Reactive Protein; Cell Differentiation; Cell Proliferation; Cellular Senescence; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelial Cells; Endothelium, Vascular; Humans; Hyperglycemia; Nitric Oxide; Oxidative Stress; Stem Cells; Vasodilation; Vasodilator Agents | 2005 |
Why are lipids not predictive of cardiovascular death in the dialysis patient?
Topics: Apolipoproteins B; Arginine; Arteriosclerosis; Blood Pressure; Cardiovascular Diseases; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Heart Diseases; Humans; Lipoprotein(a); Nutrition Disorders; Predictive Value of Tests; Renal Dialysis; Risk Assessment; Survival Rate | 1996 |
Assessment of residual insulin secretion in diabetic patients using the intravenous glucagon stimulatory test: methodological aspects and clinical applications.
Topics: Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion | 1996 |
Association of beta 3-adrenoceptor polymorphism with obesity and diabetes: current status.
Topics: Alleles; Animals; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Electrophoresis, Agar Gel; Female; Gene Frequency; Genotype; Heterozygote; Homozygote; Humans; Male; Mutagenesis; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Sex Factors; Transfection; Tryptophan | 1997 |
Experimental reduction of B-cell mass: implications for the pathogenesis of diabetes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Histocytochemistry; Humans; Immunologic Techniques; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Pancreatectomy; Rats; Rats, Inbred Strains | 1986 |
Glucose regulation in non-insulin-dependent diabetes mellitus. Interaction between pancreatic islets and the liver.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Feedback; Glucagon; Gluconeogenesis; Glucose; Glycogen; Homeostasis; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Liver; Somatostatin; Sulfonylurea Compounds | 1985 |
Treatment strategies for patients with non-insulin-dependent diabetes mellitus.
Topics: Arginine; Blood Glucose; Blood Proteins; Body Weight; Chlorpropamide; Diabetes Mellitus, Type 2; Diet, Reducing; Dietary Carbohydrates; Dietary Fiber; Drug Therapy, Combination; Glucose Tolerance Test; Humans; Insulin; Physical Exertion; Sulfonylurea Compounds; Time Factors | 1985 |
Islet-cell abnormalities in non-insulin-dependent diabetes mellitus.
Topics: Alanine; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Dietary Proteins; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans | 1985 |
92 trial(s) available for arginine and Diabetes Mellitus, Type 2
Article | Year |
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Effects of treatment with SGLT-2 inhibitors on arginine-related cardiovascular and renal biomarkers.
Topics: Arginine; Benzhydryl Compounds; Biomarkers; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucosides; Glycated Hemoglobin; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Sodium-Glucose Transporter 2 Inhibitors; Time Factors; Treatment Outcome | 2022 |
Effect of metformin on arginine and dimethylarginines in patients with advanced type 2 diabetes: A post hoc analysis of a randomized trial.
Topics: Arginine; Biomarkers; Diabetes Mellitus, Type 2; Humans; Metformin; Nitric Oxide | 2022 |
The effect of resveratrol supplementation on serum levels of asymmetric de-methyl-arginine and paraoxonase 1 activity in patients with type 2 diabetes: A randomized, double-blind controlled trial.
Topics: Adult; Arginine; Aryldialkylphosphatase; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Humans; Male; Middle Aged; Resveratrol | 2020 |
Association between 1,5-Anhydroglucitol and Acute C Peptide Response to Arginine among Patients with Type 2 Diabetes.
Topics: Adult; Arginine; Biomarkers; Blood Glucose; C-Peptide; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Insulin-Secreting Cells; Male; Middle Aged; Pancreatic Function Tests; Predictive Value of Tests | 2020 |
Topics: 3T3-L1 Cells; A Kinase Anchor Proteins; Acetates; Achilles Tendon; Acute Kidney Injury; Acute Pain; Acyclic Monoterpenes; Adenine Nucleotides; Adhesins, Escherichia coli; Adipocytes; Adipocytes, Brown; Adipogenesis; Administration, Inhalation; Administration, Oral; Adrenal Cortex Hormones; Adsorption; Adult; Aeromonas hydrophila; Africa; Aged; Aged, 80 and over; Agrobacterium tumefaciens; Air; Air Pollutants; Air Pollution; Air Pollution, Indoor; Algorithms; Alkaloids; Alkynes; Allosteric Regulation; Amines; Amino Acid Sequence; Amino Acids; Amino Acids, Branched-Chain; Aminoisobutyric Acids; Aminopyridines; Amyotrophic Lateral Sclerosis; Anaerobic Threshold; Angiography; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animal Distribution; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Ankle Joint; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Inflammatory Agents; Antibodies, Bacterial; Antifungal Agents; Antimalarials; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Antiretroviral Therapy, Highly Active; Antiviral Agents; Aotidae; Apelin; Apoptosis; Arabidopsis Proteins; Argentina; Arginine; Artemisinins; Arthritis, Experimental; Arthritis, Rheumatoid; Arthroscopy; Aspergillus; Aspergillus niger; Asteraceae; Asthma; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; Auditory Cortex; Autoantibodies; Autophagy; Bacteria; Bacterial Infections; Bacterial Proteins; Bacterial Typing Techniques; Base Composition; Base Sequence; Basketball; Beclin-1; Benzhydryl Compounds; Benzimidazoles; Benzo(a)pyrene; Benzofurans; Benzoxazines; Bereavement; beta Catenin; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Betacoronavirus; Betaine; Binding Sites; Biofilms; Biological Assay; Biological Availability; Biological Evolution; Biomarkers; Biomechanical Phenomena; Biopolymers; Biopsy; Bismuth; Blood Glucose; Blood Platelets; Blood Pressure; Body Composition; Body Weight; Bone Marrow; Bone Marrow Cells; Bone Regeneration; Boron; Botrytis; Brain Ischemia; Brain Neoplasms; Brain-Derived Neurotrophic Factor; Brazil; Breast Neoplasms; Breath Tests; Bronchoalveolar Lavage Fluid; Burkholderia; C-Reactive Protein; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Calcification, Physiologic; Calcium; Calcium Signaling; Calorimetry, Differential Scanning; Cameroon; Camptothecin; Candida; Candida albicans; Capillaries; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Carbohydrate Conformation; Carbon; Carbon Dioxide; Carbon Isotopes; Carcinoma, Ovarian Epithelial; Cardiac Output; Cardiomyopathy, Hypertrophic; Cardiotonic Agents; Cardiovascular Diseases; Caregivers; Carps; Case-Control Studies; Catalase; Catalysis; Cats; CD4 Lymphocyte Count; Cell Culture Techniques; Cell Differentiation; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Cellulose; Centrosome; Ceratopogonidae; Chickens; Child; China; Cholera Toxin; Choline; Cholinesterases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Chromatography, Reverse-Phase; Chronic Disease; Cinnamates; Cities; Citrates; Climate Change; Clinical Trials, Phase III as Topic; Coal; Coal Mining; Cohort Studies; Coinfection; Colchicine; Colony Count, Microbial; Colorectal Neoplasms; Coloring Agents; Common Cold; Complement Factor H; Computational Biology; Computer Simulation; Continuous Positive Airway Pressure; Contrast Media; Coordination Complexes; Coronary Artery Bypass; Coronavirus 3C Proteases; Coronavirus Infections; Coronavirus Protease Inhibitors; Corynebacterium glutamicum; Cosmetics; COVID-19; Creatinine; Cross-Sectional Studies; Crotonates; Crystallography, X-Ray; Cues; Culicidae; Culture Media; Curcuma; Cyclopentanes; Cyclopropanes; Cymbopogon; Cystine; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytokines; Databases, Genetic; Death; Dendritic Cells; Density Functional Theory; Depsides; Diabetes Mellitus, Type 2; Diamond; Diarylheptanoids; Dibenzofurans; Dibenzofurans, Polychlorinated; Diclofenac; Diet; Dietary Carbohydrates; Dietary Supplements; Diffusion Magnetic Resonance Imaging; Dioxins; Diphenylamine; Disease Outbreaks; Disease Susceptibility; Disulfides; Dithiothreitol; Dizocilpine Maleate; DNA Methylation; DNA-Binding Proteins; DNA, Bacterial; Dogs; Dose-Response Relationship, Drug; Double-Blind Method; Doublecortin Protein; Drosophila melanogaster; Droughts; Drug Carriers; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Dust; Dynactin Complex; Dysferlin; Echo-Planar Imaging; Echocardiography; Edaravone; Egypt; Elasticity; Electrodes; Electrolytes; Emodin; Emtricitabine; Endometriosis; Endothelium, Vascular; Endotoxins; Energy Metabolism; Energy Transfer; Enterobacteriaceae; Enterococcus faecalis; Enterotoxigenic Escherichia coli; Environmental Monitoring; Enzyme Inhibitors; Epidemiologic Factors; Epigenesis, Genetic; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Vaccines; Esophageal Neoplasms; Esophagectomy; Esophagogastric Junction; Esterases; Esterification; Ethanol; Ethiopia; Ethnicity; Eucalyptus; Evidence-Based Practice; Exercise; Exercise Tolerance; Extracorporeal Membrane Oxygenation; Family; Fatty Acids; Feedback; Female; Ferric Compounds; Fibrin Fibrinogen Degradation Products; Filtration; Fish Diseases; Flavonoids; Flavonols; Fluorodeoxyglucose F18; Follow-Up Studies; Food Microbiology; Food Preservation; Forests; Fossils; Free Radical Scavengers; Freund's Adjuvant; Fruit; Fungi; Gallium; Gender Identity; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Genes, Bacterial; Genes, Plant; Genetic Predisposition to Disease; Genitalia; Genotype; Glomerulonephritis, IGA; Glottis; Glucocorticoids; Glucose; Glucuronides; Glutathione Transferase; Glycogen Synthase Kinase 3 beta; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Grassland; Guinea Pigs; Half-Life; Head Kidney; Heart Atria; Heart Rate; Heart Septum; HEK293 Cells; Hematopoietic Stem Cells; Hemodynamics; Hep G2 Cells; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Hepatocytes; Hesperidin; High-Frequency Ventilation; High-Temperature Requirement A Serine Peptidase 1; Hippocampus; Hirudins; History, 20th Century; History, 21st Century; HIV Infections; Homeostasis; Hominidae; Housing, Animal; Humans; Hydrocarbons, Brominated; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxybutyrates; Hydroxyl Radical; Hypertension; Hypothyroidism; Image Interpretation, Computer-Assisted; Immunoconjugates; Immunogenic Cell Death; Indoles; Infant, Newborn; Infant, Premature; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Infrared Rays; Inhibitory Concentration 50; Injections, Intravenous; Interferon-gamma; Interleukin-23; Interleukin-4; Interleukin-6; Intermediate Filaments; Intermittent Claudication; Intestine, Small; Iridoid Glucosides; Iridoids; Iron; Isomerism; Isotope Labeling; Isoxazoles; Itraconazole; Kelch-Like ECH-Associated Protein 1; Ketoprofen; Kidney Failure, Chronic; Kinetics; Klebsiella pneumoniae; Lactams, Macrocyclic; Lactobacillus; Lactulose; Lakes; Lamivudine; Laparoscopy; Laparotomy; Laryngoscopy; Leucine; Limit of Detection; Linear Models; Lipid A; Lipopolysaccharides; Listeria monocytogenes; Liver; Liver Cirrhosis; Logistic Models; Longitudinal Studies; Losartan; Low Back Pain; Lung; Lupinus; Lupus Erythematosus, Systemic; Machine Learning; Macular Degeneration; Madin Darby Canine Kidney Cells; Magnetic Phenomena; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Magnetics; Malaria, Falciparum; Male; Mannans; MAP Kinase Signaling System; Mass Spectrometry; Melatonin; Membrane Glycoproteins; Membrane Proteins; Meniscectomy; Menisci, Tibial; Mephenytoin; Mesenchymal Stem Cells; Metal Nanoparticles; Metal-Organic Frameworks; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Mice, Obese; Mice, Transgenic; Microbial Sensitivity Tests; Microcirculation; MicroRNAs; Microscopy, Video; Microtubules; Microvascular Density; Microwaves; Middle Aged; Minimally Invasive Surgical Procedures; Models, Animal; Models, Biological; Models, Molecular; Models, Theoretical; Molecular Docking Simulation; Molecular Structure; Molecular Weight; Morus; Mouth Floor; Multicenter Studies as Topic; Multiple Sclerosis; Multiple Sclerosis, Relapsing-Remitting; Muscle, Skeletal; Myocardial Ischemia; Myocardium; NAD; NADP; Nanocomposites; Nanoparticles; Naphthols; Nasal Lavage Fluid; Nasal Mucosa; Neisseria meningitidis; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Neoplasms, Experimental; Neural Stem Cells; Neuroblastoma; Neurofilament Proteins; Neurogenesis; Neurons; New York; NF-E2-Related Factor 2; NF-kappa B; Nicotine; Nitriles; Nitrogen; Nitrogen Fixation; North America; Observer Variation; Occupational Exposure; Ochrobactrum; Oils, Volatile; Olea; Oligosaccharides; Omeprazole; Open Field Test; Optimism; Oregon; Oryzias; Osmolar Concentration; Osteoarthritis; Osteoblasts; Osteogenesis; Ovarian Neoplasms; Ovariectomy; Oxadiazoles; Oxidation-Reduction; Oxidative Stress; Oxygen; Ozone; p38 Mitogen-Activated Protein Kinases; Pakistan; Pandemics; Particle Size; Particulate Matter; Patient-Centered Care; Pelargonium; Peptides; Perception; Peripheral Arterial Disease; Peroxides; Pets; Pharmaceutical Preparations; Pharmacogenetics; Phenobarbital; Phenols; Phenotype; Phosphates; Phosphatidylethanolamines; Phosphines; Phospholipids; Phosphorus; Phosphorylation; Photoacoustic Techniques; Photochemotherapy; Photosensitizing Agents; Phylogeny; Phytoestrogens; Pilot Projects; Plant Components, Aerial; Plant Extracts; Plant Immunity; Plant Leaves; Plant Oils; Plants, Medicinal; Plasmodium berghei; Plasmodium falciparum; Platelet Activation; Platelet Function Tests; Pneumonia, Viral; Poaceae; Pogostemon; Poloxamer; Poly I; Poly(ADP-ribose) Polymerase Inhibitors; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Polycyclic Compounds; Polyethylene Glycols; Polylysine; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Population Dynamics; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Postoperative Complications; Postprandial Period; Potassium Cyanide; Predictive Value of Tests; Prefrontal Cortex; Pregnancy; Prepulse Inhibition; Prevalence; Procalcitonin; Prodrugs; Prognosis; Progression-Free Survival; Proline; Proof of Concept Study; Prospective Studies; Protein Binding; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Sorting Signals; Protein Structure, Secondary; Proton Pump Inhibitors; Protozoan Proteins; Psychometrics; Pulse Wave Analysis; Pyridines; Pyrrolidines; Quality of Life; Quantum Dots; Quinoxalines; Quorum Sensing; Radiopharmaceuticals; Rain; Random Allocation; Randomized Controlled Trials as Topic; Rats; Rats, Sprague-Dawley; Rats, Wistar; RAW 264.7 Cells; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, PAR-1; Receptors, CXCR4; Receptors, Estrogen; Receptors, Glucocorticoid; Receptors, Interleukin-1; Receptors, Interleukin-17; Receptors, Notch; Recombinant Fusion Proteins; Recombinant Proteins; Reducing Agents; Reflex, Startle; Regional Blood Flow; Regression Analysis; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Tract Diseases; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Risk Assessment; Risk Factors; Rituximab; RNA, Messenger; RNA, Ribosomal, 16S; ROC Curve; Rosmarinic Acid; Running; Ruthenium; Rutin; Sarcolemma; Sarcoma; Sarcopenia; Sarcoplasmic Reticulum; SARS-CoV-2; Scavenger Receptors, Class A; Schools; Seasons; Seeds; Sequence Analysis, DNA; Severity of Illness Index; Sex Factors; Shock, Cardiogenic; Short Chain Dehydrogenase-Reductases; Signal Transduction; Silver; Singlet Oxygen; Sinusitis; Skin; Skin Absorption; Small Molecule Libraries; Smoke; Socioeconomic Factors; Soil; Soil Microbiology; Solid Phase Extraction; Solubility; Solvents; Spain; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Speech; Speech Perception; Spindle Poles; Spleen; Sporothrix; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Stomach Neoplasms; Stress, Physiological; Stroke Volume; Structure-Activity Relationship; Substrate Specificity; Sulfonamides; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Rate; T-Lymphocytes, Cytotoxic; Tandem Mass Spectrometry; Temperature; Tenofovir; Terpenes; Tetracycline; Tetrapleura; Textiles; Thermodynamics; Thiobarbituric Acid Reactive Substances; Thrombin; Thyroid Hormones; Thyroid Neoplasms; Tibial Meniscus Injuries; Time Factors; Tissue Distribution; Titanium; Toluidines; Tomography, X-Ray Computed; Tooth; Tramadol; Transcription Factor AP-1; Transcription, Genetic; Transfection; Transgender Persons; Translations; Treatment Outcome; Triglycerides; Ubiquinone; Ubiquitin-Specific Proteases; United Kingdom; United States; Up-Regulation; Vascular Stiffness; Veins; Ventricular Remodeling; Viral Load; Virulence Factors; Virus Replication; Vitis; Voice; Voice Quality; Wastewater; Water; Water Pollutants, Chemical; Water-Electrolyte Balance; Weather; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Young Adult; Zoogloea | 2022 |
The Effects of Taurine Supplementation on Metabolic Profiles, Pentosidine, Soluble Receptor of Advanced Glycation End Products and Methylglyoxal in Adults With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Adult; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Lysine; Male; Metabolome; Prognosis; Pyruvaldehyde; Taurine | 2021 |
Topics: Adipose Tissue, White; Adult; Aged; Air Pollutants; Animals; Anti-Inflammatory Agents; Arginine; bcl-2-Associated X Protein; Biofuels; Biological Products; Blood Glucose; Breast Neoplasms; Caspases; CD36 Antigens; Cell Communication; Cell Proliferation; Cell Survival; Cooking; Cross-Sectional Studies; Databases, Factual; Diabetes Mellitus, Type 2; Diphtheria Toxin; Double-Blind Method; Exenatide; Extracellular Polymeric Substance Matrix; Feasibility Studies; Female; Filgrastim; Fruit; Galactose; Gene Deletion; Gene Knockdown Techniques; Glucagon; Glucagon-Like Peptide-1 Receptor; Glucagon-Secreting Cells; Glucose; Glycated Hemoglobin; Hematopoietic Stem Cell Mobilization; Household Articles; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Lung; Lymphoma; Male; Metals, Heavy; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Nanoparticles; Neoplasms; Obesity; Obstetrics; Odds Ratio; Oxygen; Peripheral Blood Stem Cell Transplantation; Photochemotherapy; Plant Extracts; Polyethylene Glycols; Polyglutamic Acid; Porosity; Postprandial Period; Prospective Studies; Quality of Life; Receptors, Glucagon; Receptors, LDL; Receptors, Somatostatin; Registries; Rhodophyta; Rhodotorula; Risk Factors; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Somatostatin; Stilbenes; Terminalia; Treatment Outcome; United States; Venoms | 2021 |
Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease.
Topics: Acetylcysteine; Administration, Oral; Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Female; Glutamine; Humans; Isoleucine; Leucine; Liver; Magnetic Resonance Imaging; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Single-Blind Method; Treatment Outcome; Valine | 2021 |
Decreased diabetes risk over 9 year after 18-month oral L-arginine treatment in middle-aged subjects with impaired glucose tolerance and metabolic syndrome (extension evaluation of L-arginine study).
Topics: Administration, Oral; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diet; Endothelial Cells; Exercise; Follow-Up Studies; Glucose Intolerance; Humans; Insulin; Insulin Resistance; Metabolic Syndrome; Middle Aged; Oxidative Stress; Sample Size; Surveys and Questionnaires; Treatment Outcome | 2018 |
l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor-α levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial.
Topics: Adipose Tissue; Adult; Arginine; Blood Glucose; Body Composition; Carnosine; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Fasting; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Triglycerides; Tumor Necrosis Factor-alpha | 2018 |
Effects of linagliptin on endothelial function and postprandial lipids in coronary artery disease patients with early diabetes: a randomized, placebo-controlled, double-blind trial.
Topics: Aged; Arginine; Austria; Biomarkers; Blood Glucose; Citrulline; Coronary Artery Disease; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Endothelium, Vascular; Female; Glycated Hemoglobin; Humans; Linagliptin; Lipids; Male; Middle Aged; Ornithine; Postprandial Period; Prospective Studies; Time Factors; Treatment Outcome; Vasodilation | 2018 |
Asymmetric dimethylarginine and soluble inter-cellular adhesion molecule-1 serum levels alteration following ginger supplementation in patients with type 2 diabetes: a randomized double-blind, placebo-controlled clinical trial.
Topics: Adult; Arginine; Biomarkers; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Plant Extracts; Zingiber officinale | 2018 |
Serum Levels of Protein-Bound Methylglyoxal-Derived Hydroimidazolone-1 are Independently Correlated with Asymmetric Dimethylarginine.
Topics: Aged; Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Imidazoles; Inflammation; Male; Middle Aged; Protein Binding; Pyruvaldehyde; Vascular Stiffness | 2019 |
Soluble receptor for advanced glycation end-product (sRAGE)/pentosidine ratio: a potential risk factor determinant for type 2 diabetic retinopathy.
Topics: Adult; Advanced Oxidation Protein Products; Aged; Arginine; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glutathione Peroxidase; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Risk Factors; Superoxide Dismutase | 2013 |
Insulin-mediated activation of the L-arginine nitric oxide pathway in man, and its impairment in diabetes.
Topics: Adult; Arginine; Biological Transport; Case-Control Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Humans; Insulin; Male; Middle Aged; Nitric Oxide; Nitroprusside; Vasodilation | 2013 |
Variation in inflammatory markers and glycemic parameters after 12 months of exenatide plus metformin treatment compared with metformin alone: a randomized placebo-controlled trial.
Topics: Aged; Arginine; Biomarkers; Blood Glucose; Body Mass Index; Body Weight; C-Peptide; Chimerin Proteins; Diabetes Mellitus, Type 2; Diet; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Exenatide; Female; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Inflammation; Insulin Resistance; Male; Metformin; Middle Aged; Peptides; Resistin; Risk Factors; Serpins; Venoms | 2013 |
Pioglitazone decreases asymmetric dimethylarginine levels in patients with impaired glucose tolerance or type 2 diabetes.
Topics: Aged; Aged, 80 and over; Arginine; Diabetes Mellitus, Type 2; Female; Fibronectins; Glucose Intolerance; Humans; Male; Middle Aged; Pioglitazone; Regression Analysis; Sulfonylurea Compounds; Thiazolidinediones | 2013 |
Restoring Insulin Secretion (RISE): design of studies of β-cell preservation in prediabetes and early type 2 diabetes across the life span.
Topics: Adolescent; Adult; Aged; Arginine; Blood Glucose; C-Peptide; Child; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Gastroplasty; Glucagon-Like Peptide 1; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Liraglutide; Male; Metformin; Middle Aged; Prediabetic State; Young Adult | 2014 |
The impact of salsalate treatment on serum levels of advanced glycation end products in type 2 diabetes.
Topics: Adiponectin; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Pyruvaldehyde; Salicylates | 2014 |
Effect of vildagliptin add-on treatment to metformin on plasma asymmetric dimethylarginine in type 2 diabetes mellitus patients.
Topics: Adamantane; Adult; Aged; Arginine; C-Reactive Protein; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Female; Fibrinogen; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Nitric Oxide; Nitriles; Pyrrolidines; Vildagliptin | 2014 |
Serum amyloid a truncations in type 2 diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Cholesterol, HDL; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Serum Amyloid A Protein | 2015 |
Use of a urea, arginine and carnosine cream versus a standard emollient glycerol cream for treatment of severe xerosis of the feet in patients with type 2 diabetes: a randomized, 8 month, assessor-blinded, controlled trial.
Topics: Administration, Cutaneous; Aged; Arginine; Carnosine; Diabetes Mellitus, Type 2; Emollients; Female; Glycerol; Humans; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Skin Diseases; Urea | 2015 |
Differential associations of circulating asymmetric dimethylarginine and cell adhesion molecules with metformin use in patients with type 2 diabetes mellitus and stable coronary artery disease.
Topics: Aged; Aged, 80 and over; Arginine; Cell Adhesion Molecules; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Metformin; Middle Aged; Time Factors | 2015 |
Reduction in asymmetric dimethylarginine plasma levels by coenzyme Q10 supplementation in patients with type 2 diabetes mellitus.
Topics: Adult; Aged; Antioxidants; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Ubiquinone | 2015 |
Elevated Serum Pentosidine and Decreased Serum IGF-I Levels are Associated with Loss of Muscle Mass in Postmenopausal Women with Type 2 Diabetes Mellitus.
Topics: Aged; Arginine; Diabetes Mellitus, Type 2; Female; Humans; Insulin-Like Growth Factor I; Lysine; Middle Aged; Muscle, Skeletal; Postmenopause; Sarcopenia | 2016 |
Antihyperglycemic effect of short-term arginyl-fructose supplementation in subjects with prediabetes and newly diagnosed type 2 diabetes: randomized, double-blinded, placebo-controlled trial.
Topics: Adult; Aged; Area Under Curve; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Double-Blind Method; Fatty Acids, Nonesterified; Female; Fructose; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Male; Middle Aged; Prediabetic State; Predictive Value of Tests; Republic of Korea; ROC Curve; Time Factors; Treatment Outcome; Young Adult | 2015 |
Arginase Inhibition Improves Microvascular Endothelial Function in Patients With Type 2 Diabetes Mellitus.
Topics: Acetylcholine; Aged; Arginase; Arginine; Cardiovascular Agents; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Laser-Doppler Flowmetry; Male; Microvessels; Middle Aged; Nitroprusside; Ornithine; Peripheral Vascular Diseases; Severity of Illness Index; Vascular Resistance; Vasodilation; Vasodilator Agents | 2016 |
Calorie restriction and not glucagon-like peptide-1 explains the acute improvement in glucose control after gastric bypass in Type 2 diabetes.
Topics: Adipose Tissue; Adult; Aged; Amino Acids; Arginine; Blood Glucose; Body Composition; Caloric Restriction; Chromium; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Glucagon-Like Peptide 1; Glucose; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Insulin Secretion; Lipase; Liver; Male; Membrane Proteins; Middle Aged; Nicotinic Acids; Pancreas; Triglycerides | 2016 |
The effects of linagliptin on endothelial function and global arginine bioavailability ratio in coronary artery disease patients with early diabetes: study protocol for a randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Austria; Biological Availability; Biomarkers; Brachial Artery; Clinical Protocols; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dipeptidyl-Peptidase IV Inhibitors; Double-Blind Method; Endothelium, Vascular; Female; Humans; Linagliptin; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Time Factors; Treatment Outcome | 2016 |
Effect of trelagliptin on vascular endothelial functions and serum adiponectin level in patients with type 2 diabetes: a preliminary single-arm prospective pilot study.
Topics: Adiponectin; Adult; Aged; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Endothelium, Vascular; Female; Glycated Hemoglobin; Humans; Japan; Male; Middle Aged; Pilot Projects; Prospective Studies; Time Factors; Treatment Outcome; Up-Regulation; Uracil; Vasodilation | 2016 |
L-arginine and tetrahydrobiopterin protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery disease.
Topics: Aged; Arginine; Biopterins; Blood Flow Velocity; Cardiovascular Agents; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelium, Vascular; Female; Forearm; Humans; Infusions, Intra-Arterial; Male; Regional Blood Flow; Reperfusion Injury; Treatment Outcome; Vasodilation; Vasodilator Agents | 2009 |
One-year treatment with exenatide improves beta-cell function, compared with insulin glargine, in metformin-treated type 2 diabetic patients: a randomized, controlled trial.
Topics: Arginine; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Exenatide; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin; Insulin Glargine; Insulin Secretion; Insulin-Secreting Cells; Insulin, Long-Acting; Kinetics; Male; Metformin; Middle Aged; Peptides; Venoms | 2009 |
Effects of therapy in type 1 and type 2 diabetes mellitus with a peptide derived from islet neogenesis associated protein (INGAP).
Topics: Adolescent; Adult; Aged; Analysis of Variance; Antigens, Neoplasm; Area Under Curve; Arginine; Biomarkers, Tumor; Blood Glucose; Body Mass Index; C-Peptide; Cytokines; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Double-Blind Method; Fasting; Female; Glutamate Decarboxylase; Glycated Hemoglobin; Humans; Injections, Subcutaneous; Insulin; Insulin-Secreting Cells; Lectins, C-Type; Male; Middle Aged; Pancreatitis-Associated Proteins; Peptide Fragments; Proinsulin; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Regeneration; Treatment Outcome; Young Adult | 2009 |
Postprandial vascular effects of VIAject compared with insulin lispro and regular human insulin in patients with type 2 diabetes.
Topics: Arginine; Blood Glucose; Blood Vessels; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Lispro; Male; Microcirculation; Middle Aged; Postprandial Period; Tyrosine | 2010 |
Treatment with alpha-lipoic acid reduces asymmetric dimethylarginine in patients with type 2 diabetes mellitus.
Topics: Arginine; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Male; Middle Aged; Thioctic Acid | 2010 |
Lack of lipotoxicity effect on {beta}-cell dysfunction in ketosis-prone type 2 diabetes.
Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Diabetic Ketoacidosis; Drug Administration Schedule; Fat Emulsions, Intravenous; Female; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Middle Aged; Obesity; Pancreatic Function Tests; Remission Induction; Withholding Treatment | 2010 |
Postprandial hyperglycemia is a determinant of platelet activation in early type 2 diabetes mellitus.
Topics: Acarbose; Aged; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; CD40 Ligand; Diabetes Mellitus, Type 2; Dinoprost; Double-Blind Method; Enzyme Inhibitors; Female; Glycated Hemoglobin; Glycoside Hydrolase Inhibitors; Humans; Hyperglycemia; Hypoglycemic Agents; Italy; Lipid Peroxidation; Male; Middle Aged; P-Selectin; Platelet Activation; Postprandial Period; Thromboxane B2; Time Factors; Treatment Outcome | 2010 |
Effect of L-arginine on the microcirculation in the neuropathic diabetic foot in Type 2 diabetes mellitus: a double-blind, placebo-controlled study.
Topics: Arginine; Diabetes Mellitus, Type 2; Diabetic Foot; Double-Blind Method; Female; Humans; Male; Microcirculation; Middle Aged; Placebos; Treatment Outcome | 2010 |
Effects of metformin and pioglitazone on serum pentosidine levels in type 2 diabetes mellitus.
Topics: Aged; Arginine; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lysine; Male; Metformin; Middle Aged; Pioglitazone; Thiazolidinediones; Time Factors | 2011 |
The impact of pioglitazone on ADMA and oxidative stress markers in patients with type 2 diabetes.
Topics: Academic Medical Centers; Arginine; Biomarkers; Cross-Over Studies; Diabetes Mellitus, Type 2; Dinoprost; F2-Isoprostanes; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Pioglitazone; Prospective Studies; South Carolina; Thiazolidinediones; Time Factors; Treatment Outcome | 2012 |
Addition of liraglutide in patients with Type 2 diabetes well controlled on metformin monotherapy improves several markers of vascular function.
Topics: Adult; Aged; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; E-Selectin; Endothelium, Vascular; Female; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Liraglutide; Male; Metformin; Microcirculation; Middle Aged; Plasminogen Activator Inhibitor 1; Proinsulin; Prospective Studies | 2012 |
Effect of a long-term oral l-arginine supplementation on glucose metabolism: a randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Glucose Intolerance; Glucose Tolerance Test; Humans; Incidence; Male; Middle Aged; Risk Reduction Behavior; Time Factors | 2012 |
Multifactorial risk factor intervention in patients with Type 2 diabetes improves arginine bioavailability ratios.
Topics: Aged; Anticholesteremic Agents; Arginine; Biological Availability; Blood Pressure; Cholesterol, LDL; Citrulline; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Ornithine; Prospective Studies; Risk Factors; Time Factors | 2012 |
An urea, arginine and carnosine based cream (Ureadin Rx Db ISDIN) shows greater efficacy in the treatment of severe xerosis of the feet in Type 2 diabetic patients in comparison with glycerol-based emollient cream. A randomized, assessor-blinded, controll
Topics: Administration, Topical; Adult; Aged; Arginine; Carnosine; Diabetes Mellitus, Type 2; Diabetic Foot; Drug Combinations; Emollients; Female; Foot Dermatoses; Glycerol; Humans; Male; Middle Aged; Severity of Illness Index; Single-Blind Method; Skin Cream; Treatment Outcome; Urea | 2012 |
The R230C variant of the ATP binding cassette protein A1 (ABCA1) gene is associated with a decreased response to glyburide therapy in patients with type 2 diabetes mellitus.
Topics: Adult; Aged; Amino Acid Substitution; Arginine; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cysteine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Resistance; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glyburide; Humans; Hypoglycemic Agents; Male; Middle Aged; Mutation, Missense; Polymorphism, Single Nucleotide; Single-Blind Method; Young Adult | 2013 |
L-arginine infusion decreases plasma total homocysteine concentrations through increased nitric oxide production and decreased oxidative status in Type II diabetic patients.
Topics: Arginine; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Homocysteine; Humans; Infusions, Intravenous; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Osmolar Concentration; Oxidative Stress; Reference Values; Sulfhydryl Compounds | 2002 |
Gliclazide improves anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes.
Topics: Adult; Aged; Antioxidants; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Free Radicals; Gliclazide; Glyburide; Humans; Hypoglycemic Agents; Injections, Intravenous; Lipid Peroxides; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Vasodilation | 2002 |
Oral arginine reduces systemic blood pressure in type 2 diabetes: its potential role in nitric oxide generation.
Topics: Adult; Arginine; Blood Pressure; C-Peptide; Citrulline; Cross-Over Studies; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Prospective Studies | 2002 |
Influence of rosiglitazone treatment on beta-cell function in type 2 diabetes: evidence of an increased ability of glucose to entrain high-frequency insulin pulsatility.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Entropy; Female; Glucose; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Islets of Langerhans; Male; Middle Aged; Rosiglitazone; Stimulation, Chemical; Thiazoles; Thiazolidinediones | 2003 |
Effects of a combination of recombinant human growth hormone with metformin on glucose metabolism and body composition in patients with metabolic syndrome.
Topics: Aged; Arginine; Blood Glucose; Blood Pressure; Body Composition; Body Constitution; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Fibrinogen; Glucose Tolerance Test; Glycated Hemoglobin; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin Resistance; Insulin-Like Growth Factor I; Lipids; Male; Metabolic Syndrome; Metformin; Middle Aged; Obesity; Placebos; Testosterone | 2004 |
Oral L-arginine and vitamins E and C improve endothelial function in women with type 2 diabetes.
Topics: Administration, Oral; Adult; Arginine; Ascorbic Acid; Blood Flow Velocity; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Forearm; Humans; Middle Aged; Premenopause; Regional Blood Flow; Vasodilation; Vasodilator Agents; Vitamin E | 2003 |
Loss of entrainment of high-frequency plasma insulin oscillations in type 2 diabetes is likely a glucose-specific beta-cell defect.
Topics: Adult; Aged; Arginine; Biological Clocks; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucose; Hemostasis; Humans; Injections, Intravenous; Insulin; Islets of Langerhans; Male; Middle Aged; Oscillometry; Periodicity | 2004 |
Diet-induced weight loss is associated with an improvement in beta-cell function in older men.
Topics: Age Factors; Aged; Arginine; Blood Glucose; Body Composition; Diabetes Mellitus, Type 2; Diet, Reducing; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Life Style; Male; Middle Aged; Obesity; Weight Loss | 2004 |
Reduced hepatic insulin extraction in response to gastric inhibitory polypeptide compensates for reduced insulin secretion in normal-weight and normal glucose tolerant first-degree relatives of type 2 diabetic patients.
Topics: Adult; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Family Health; Female; Gastric Inhibitory Polypeptide; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperglycemia; Insulin; Insulin Secretion; Liver; Male | 2004 |
Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes.
Topics: Arginine; Body Mass Index; Diabetes Mellitus, Type 2; DNA; DNA Mutational Analysis; Female; Humans; Male; Obesity; Odds Ratio; Pedigree; Peptide YY; Polymorphism, Genetic; Risk Factors; Sequence Deletion | 2005 |
Association of Gly972Arg variant of insulin receptor substrate-1 with metabolic features in women with polycystic ovary syndrome.
Topics: Analysis of Variance; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Genetic Variation; Glycine; Humans; Insulin; Insulin Receptor Substrate Proteins; Phosphoproteins; Polycystic Ovary Syndrome | 2005 |
No effect of B vitamins on ADMA levels in patients at increased cardiovascular risk.
Topics: Adolescent; Adult; Arginine; Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Female; Folic Acid; Humans; Hyperhomocysteinemia; Linear Models; Male; Middle Aged; Pyridoxine; Risk Factors; Time Factors; Treatment Failure; Vitamin B Complex | 2006 |
Beneficial effects of a long-term oral L-arginine treatment added to a hypocaloric diet and exercise training program in obese, insulin-resistant type 2 diabetic patients.
Topics: Administration, Oral; Arginine; Blood Glucose; Blood Pressure; Body Weight; Combined Modality Therapy; Diabetes Mellitus, Type 2; Diet, Reducing; Energy Intake; Exercise; Female; Fructosamine; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Triglycerides | 2006 |
Effects of atorvastatin and vitamin C on forearm hyperaemic blood flow, asymmentrical dimethylarginine levels and the inflammatory process in patients with type 2 diabetes mellitus.
Topics: Anti-Inflammatory Agents; Antioxidants; Arginine; Ascorbic Acid; Atorvastatin; Cytokines; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Forearm; Heptanoic Acids; Humans; Hyperemia; Male; Middle Aged; Pyrroles; Regional Blood Flow; Single-Blind Method; Vitamins | 2007 |
Effect of iloprost on plasma asymmetric dimethylarginine and plasma and platelet serotonin in patients with peripheral arterial occlusive disease.
Topics: Aged; Aged, 80 and over; Arginine; Arterial Occlusive Diseases; Blood Platelets; Blood Pressure; Diabetes Mellitus, Type 2; Drug Administration Schedule; Exercise Test; Female; Humans; Iloprost; Infusions, Intravenous; Male; Peripheral Vascular Diseases; Platelet Aggregation Inhibitors; Serotonin; Treatment Outcome | 2006 |
Effects of pioglitazone and metformin on beta-cell function in nondiabetic subjects at high risk for type 2 diabetes.
Topics: Adult; Aged; Arginine; Body Composition; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Metformin; Middle Aged; Pioglitazone; Risk Factors; Thiazolidinediones | 2007 |
Beneficial metabolic effects of nateglinide versus acarbose in patients with newly-diagnosed type 2 diabetes.
Topics: Acarbose; Arginine; Blood Glucose; Cross-Over Studies; Cyclohexanes; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Insulin; Lipids; Male; Middle Aged; Nateglinide; Phenylalanine; Prospective Studies | 2007 |
Hyperbaric oxygen therapy mediates increased nitric oxide production associated with wound healing: a preliminary study.
Topics: Arginine; Chromatography, High Pressure Liquid; Chronic Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Exudates and Transudates; Fasting; Female; Granulation Tissue; Humans; Hyperbaric Oxygenation; Male; Middle Aged; Nitric Oxide; Oxidation-Reduction; Time Factors; Treatment Outcome; Wound Healing; Wounds and Injuries | 2007 |
Effect of nebivolol and metoprolol treatments on serum asymmetric dimethylarginine levels in hypertensive patients with type 2 diabetes mellitus.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Arginine; Benzopyrans; Biomarkers; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Ethanolamines; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nebivolol; Prospective Studies; Treatment Outcome; Triglycerides | 2007 |
Long-term N-acetylcysteine and L-arginine administration reduces endothelial activation and systolic blood pressure in hypertensive patients with type 2 diabetes.
Topics: Acetylcysteine; Administration, Oral; Aged; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Endothelium, Vascular; Humans; Hypertension; Hypoglycemic Agents; Male; Middle Aged; Placebos; Systole | 2008 |
Serum levels of the advanced glycation end products Nepsilon-carboxymethyllysine and pentosidine are not influenced by treatment with the angiotensin receptor II type 1 blocker irbesartan in patients with type 2 diabetic nephropathy and hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Biphenyl Compounds; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Hypertension; Irbesartan; Linear Models; Lysine; Male; Middle Aged; Statistics, Nonparametric; Tetrazoles | 2008 |
Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Arginine; Benzimidazoles; Benzoates; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Proteinuria; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 2008 |
Pirenzepine decreases basal and stimulated GH secretion in patients with type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Adult; Arginine; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Growth Hormone; Humans; Male; Middle Aged; Pirenzepine | 1994 |
Insulin production following intravenous glucose, arginine, and valine: different pattern in patients with impaired glucose tolerance and non-insulin-dependent diabetes mellitus.
Topics: Adult; Arginine; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Humans; Injections, Intravenous; Insulin; Male; Middle Aged; Valine | 1994 |
Dietary fish oil augments nitric oxide production or release in patients with type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Acetylcholine; Arachidonic Acid; Arginine; Blood Glucose; Blood Platelets; Blood Pressure; Cell Membrane; Cholesterol; Diabetes Mellitus, Type 2; Dietary Fats; Docosahexaenoic Acids; Double-Blind Method; Eicosapentaenoic Acid; Female; Fish Oils; Forearm; Glycated Hemoglobin; Heart Rate; Hemodynamics; Humans; Male; Membrane Lipids; Middle Aged; Nitric Oxide; Olive Oil; omega-N-Methylarginine; Plant Oils; Triglycerides; Vascular Resistance | 1993 |
Metformin improves hemodynamic and rheological responses to L-arginine in NIDDM patients.
Topics: Analysis of Variance; Arginine; Blood Glucose; Blood Pressure; Blood Viscosity; Diabetes Mellitus, Type 2; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Hypoglycemic Agents; Insulin; Male; Metformin; Middle Aged; Norepinephrine; Platelet Aggregation; Rheology | 1996 |
Effects of aspirin or basic amino acids on collagen cross-links and complications in NIDDM.
Topics: Analysis of Variance; Arginine; Aspirin; Biopsy; Blood Glucose; Collagen; Cross-Linking Reagents; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Double-Blind Method; Glycated Hemoglobin; Lysine; Placebos; Skin | 1997 |
Effects of low-dose L-arginine on insulin-mediated vasodilatation and insulin sensitivity.
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Insulin; Insulin Resistance; Insulin-Like Growth Factor I; Male; Middle Aged; Obesity; Vasodilation | 1997 |
Relative hyperproinsulinemia of NIDDM persists despite the reduction of hyperglycemia with insulin or sulfonylurea therapy.
Topics: Adult; Aged; Arginine; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Fasting; Gliclazide; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Middle Aged; Proinsulin | 1997 |
[Response of the coronary arteries to cold test and flow velocity increase is improved by deferoxamine but not by L-arginine in diabetic patients].
Topics: Arginine; Blood Flow Velocity; Cold Temperature; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Deferoxamine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Hemodynamics; Humans; Male; Middle Aged; Nitric Oxide; Vasoconstriction; Vasodilation; Vasodilator Agents | 1997 |
The stimulation of insulin secretion in non-insulin-dependent diabetic patients by amino acids and gliclazide in the basal and hyperglycemic state.
Topics: Aged; Arginine; Blood Glucose; C-Peptide; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Gliclazide; Glucose Clamp Technique; Humans; Hyperglycemia; Hypoglycemic Agents; Infusions, Intravenous; Insulin; Insulin Secretion; Leucine; Male; Middle Aged; Time Factors | 1997 |
Effects of perindopril and carvedilol on endothelium-dependent vascular functions in patients with diabetes and hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arginine; Blood Pressure; Blood Viscosity; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Double-Blind Method; Endothelium, Vascular; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Indoles; Leg; Male; Middle Aged; Perindopril; Platelet Aggregation; Propanolamines; Reference Values; Regional Blood Flow; Rheology; Vascular Resistance | 1998 |
Plasma levels of pentosidine in diabetic patients: an advanced glycation end product.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Analysis of Variance; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Male; Middle Aged; Myocardial Ischemia; Regression Analysis; Sensitivity and Specificity; Severity of Illness Index | 1998 |
Impaired endothelium-dependent vascular responses of retinal and intrarenal arteries in patients with type 2 diabetes.
Topics: Adult; Albuminuria; Arginine; Blood Glucose; Blood Pressure; Brachial Artery; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Heart Rate; Humans; Insulin; Male; Middle Aged; Nitric Oxide Donors; Nitroglycerin; Regression Analysis; Renal Artery; Retinal Artery; Sodium Chloride; Ultrasonography; Vasodilator Agents | 1999 |
Insulin and glucagon secretion in patients with slowly progressing autoimmune diabetes (LADA).
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; Humans; Insulin; Male | 2000 |
A novel hyperglycaemic clamp for characterization of islet function in humans: assessment of three different secretagogues, maximal insulin response and reproducibility.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptides; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Peptide Fragments; Protein Precursors; Reproducibility of Results | 2000 |
Acute elevations of plasma asymmetric dimethylarginine and impaired endothelial function in response to a high-fat meal in patients with type 2 diabetes.
Topics: Adult; Aged; Arginine; Diabetes Mellitus, Type 2; Dietary Fats; Endothelium, Vascular; Female; Humans; Lipids; Male; Middle Aged; Triglycerides; Vasodilation | 2000 |
Long-term oral L-arginine administration improves peripheral and hepatic insulin sensitivity in type 2 diabetic patients.
Topics: Administration, Oral; Arginine; Blood Glucose; Blood Pressure; Body Weight; Cyclic GMP; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Forearm; Glucose Clamp Technique; Glycated Hemoglobin; Heart Rate; Humans; Insulin; Insulin Secretion; Liver; Middle Aged; Potassium; Reference Values; Regional Blood Flow | 2001 |
Identification of N(omega)-carboxymethylarginine, a new advanced glycation endproduct in serum proteins of diabetic patients: possibility of a new marker of aging and diabetes.
Topics: Aging; Arginine; Biomarkers; Calibration; Chromatography, Liquid; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Middle Aged; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2001 |
Effect of acute hyperglycemia on insulin secretion in humans.
Topics: Acute Disease; Adult; Aged; Arginine; C-Peptide; Diabetes Mellitus, Type 2; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged | 2002 |
Paradoxical decrease in plasma NOx by L-arginine load in diabetic and non-diabetic subjects.
Topics: Arginine; Blood Glucose; Blood Pressure; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 2002 |
Metformin treatment lowers asymmetric dimethylarginine concentrations in patients with type 2 diabetes.
Topics: Arginine; Blood Glucose; Creatinine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Sulfonylurea Compounds; Treatment Outcome | 2002 |
Nicardipine does not cause deterioration of glucose homoeostasis in man: a placebo controlled study in elderly hypertensives with and without diabetes mellitus.
Topics: Aged; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Tolerance Test; Homeostasis; Humans; Hypertension; Insulin; Male; Nicardipine; Reproducibility of Results | 1992 |
Decreased insulin secretory capacity and normal pancreatic B-cell glucose sensitivity in non-obese patients with NIDDM.
Topics: Adult; Aged; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged | 1991 |
Fenfluramine increases insulin action in patients with NIDDM.
Topics: Adult; Aged; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Fenfluramine; Glyburide; Glycated Hemoglobin; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Reference Values | 1989 |
Dietary magnesium supplements improve B-cell response to glucose and arginine in elderly non-insulin dependent diabetic subjects.
Topics: Aged; Arginine; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucagon; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Magnesium; Male; Random Allocation | 1989 |
[Effects of nifedipine on carbohydrate metabolism in the non-insulin dependent diabetic].
Topics: Adult; Aged; Arginine; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-Blind Method; Glucagon; Glucose Tolerance Test; Growth Hormone; Humans; Insulin; Male; Middle Aged; Nifedipine; Prospective Studies; Random Allocation | 1985 |
411 other study(ies) available for arginine and Diabetes Mellitus, Type 2
Article | Year |
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Plasma Arginine and Citrulline are Elevated in Diabetic Retinopathy.
Topics: Adult; Arginine; Chromatography, Liquid; Citrulline; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Tandem Mass Spectrometry | 2022 |
Protein arginine N-methyltransferase 1 gene polymorphism is associated with proliferative diabetic retinopathy in a Japanese population.
Topics: Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Gene Frequency; Genotype; Humans; Japan; Methyltransferases; Polymorphism, Single Nucleotide; Protein-Arginine N-Methyltransferases; Repressor Proteins | 2022 |
Oral L-Arginine (5 g/day) for 14 Days Improves Microcirculatory Function in Healthy Young Women and Healthy and Type 2 Diabetes Mellitus Elderly Women.
Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Arginine; Arterial Pressure; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Forearm; Hemodynamics; Humans; Microcirculation; Microscopic Angioscopy; Nails; Plethysmography; Sex Factors; Time Factors; Treatment Outcome; Vasodilation; Young Adult | 2022 |
Neuropeptide Y1 receptor antagonism protects β-cells and improves glycemic control in type 2 diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Glucose; Glycemic Control; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Neuropeptide Y; Obesity; Receptors, Neuropeptide Y | 2022 |
Short-Term Effects of Supplemental L-Arginine, Diosmin, Troxerutin, and Hesperidin in Diabetic Patients: A Pilot Study.
Topics: Antioxidants; Apolipoprotein A-I; Apolipoprotein B-100; Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Diosmin; Endothelium, Vascular; Female; Hesperidin; Humans; Hydroxyethylrutoside; Male; Middle Aged; Oxidative Stress; Pilot Projects; Prospective Studies | 2021 |
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats.
Topics: Animals; Arginase; Arginine; Diabetes Mellitus, Type 2; Diet, High-Fat; Humans; Hypercholesterolemia; Hyperglycemia; Hypoglycemic Agents; Male; Mice; Nitric Oxide; Rats; Streptozocin; Valine | 2022 |
Protein Kinase C (Pkc)-δ Mediates Arginine-Induced Glucagon Secretion in Pancreatic α-Cells.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Glucagon; Glucagon-Secreting Cells; Mice; Protein Kinase C-delta | 2022 |
A New Case of Hb Headington (
Topics: Aged; Arginine; beta-Globins; Diabetes Mellitus, Type 2; DNA; Female; Glycated Hemoglobin; Hemoglobins, Abnormal; Humans; Mutation; Oxygen; Serine | 2022 |
Serum untargeted metabolomics analysis of the mechanisms of evodiamine on type 2 diabetes mellitus model rats.
Topics: Amino Sugars; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Metabolomics; Nucleotides; Proline; Quinazolines; Rats; Streptozocin; Tryptophan | 2022 |
Protective effects of L-arginine on cognitive deficits and biochemical parameters in an experimental model of type-2 diabetes mellitus induced Alzheimer's disease in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Arginine; Cognition; Diabetes Mellitus, Type 2; Models, Theoretical; NG-Nitroarginine Methyl Ester; Rats; Streptozocin | 2022 |
Alcohol Drinks Induce Acute Lowering in Circulating l-Arginine in Obese and Type 2 Diabetic Subjects.
Topics: Alcohol Drinking; Arginine; Diabetes Mellitus, Type 2; Humans; Obesity; Overweight; Weight Loss | 2022 |
GLP-1 Receptor Blockade Reduces Stimulated Insulin Secretion in Fasted Subjects With Low Circulating GLP-1.
Topics: Arginine; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Fasting; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Humans; Insulin; Insulin Secretion; Sitagliptin Phosphate | 2022 |
Metformin encapsulated gold nanoparticles (MTF-GNPs): A promising antiglycation agent.
Topics: Arginine; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Gold; Humans; Hypoglycemic Agents; Lysine; Metal Nanoparticles; Metformin; Ribose; Serum Albumin, Bovine | 2022 |
Pathophysiological correlation of arginase-1 in development of type 2 diabetes from obesity in adolescents.
Topics: Adolescent; Arginase; Arginine; Diabetes Mellitus, Type 2; Endothelial Cells; Humans; Male; Pediatric Obesity | 2023 |
Arginine Reduces Glycation in γ
Topics: Alzheimer Disease; AMP-Activated Protein Kinases; Animals; Arginine; Diabetes Mellitus, Type 2; Mice; Plaque, Amyloid | 2022 |
Effects of Chicken Serum Metabolite Treatment on the Blood Glucose Control and Inflammatory Response in Streptozotocin-Induced Type 2 Diabetes Mellitus Rats.
Topics: Animals; Arginine; Blood Glucose; Chickens; Chromatography, Liquid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glycemic Control; Hyperglycemia; Hypoglycemic Agents; Insulin; Rats; Streptozocin; Tandem Mass Spectrometry | 2022 |
Associations of serum amino acids related to urea cycle with risk of chronic kidney disease in Chinese with type 2 diabetes.
Topics: Arginine; Citrulline; Diabetes Mellitus, Type 2; East Asian People; Female; Humans; Male; Ornithine; Renal Insufficiency, Chronic; Urea | 2023 |
Quantitative, Targeted Analysis of Gut Microbiota Derived Metabolites Provides Novel Biomarkers of Early Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients.
Topics: Arginine; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Gastrointestinal Microbiome; Humans; Indican; Metabolomics; Sulfates | 2023 |
Dietary intakes of methionine, threonine, lysine, arginine and histidine increased risk of type 2 diabetes in Chinese population: does the mediation effect of obesity exist?
Topics: Amino Acids; Arginine; Diabetes Mellitus, Type 2; Diet; East Asian People; Histidine; Humans; Lysine; Male; Methionine; Obesity; Racemethionine; Risk Factors; Threonine | 2023 |
Preliminary observational study of metabonomics in patients with early and late-onset type 2 diabetes mellitus based on UPLC-Q-TOF/MS.
Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Humans; Lipid Metabolism; Metabolomics; Signal Transduction | 2023 |
Plasma amino acid signatures define types of pediatric diabetes.
Topics: Adolescent; Arginine; Child; Citrulline; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fabaceae; Glutamine; Humans; Methionine; Pilot Projects; Racemethionine | 2023 |
Bone material strength in normoglycemic and hyperglycemic black and white older adults.
Topics: Absorptiometry, Photon; Aged; Arginine; Black or African American; Blood Glucose; Bone Density; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Femur Neck; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Prediabetic State; Tibia; United States; White People | 2019 |
Bone Histomorphometry in Young Patients With Type 2 Diabetes is Affected by Disease Control and Chronic Complications.
Topics: Adult; Arginine; Blood Glucose; Bone Development; Bone Diseases; Cancellous Bone; Chronic Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Insulin-Like Growth Factor I; Lysine; Male | 2020 |
Dynamic derangement in amino acid profile during and after a stroke-like episode in adult-onset mitochondrial disease: a case report.
Topics: Arginine; Aspartic Acid; Biomarkers; Deafness; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Growth Differentiation Factor 15; Humans; Male; MELAS Syndrome; Middle Aged; Mitochondrial Diseases; Mutation | 2019 |
Restoration of Adiponectin-Connexin43 Signaling Mitigates Myocardial Inflammation and Dysfunction in Diabetic Female Rats.
Topics: Adiponectin; Animals; Arginine; Connexin 43; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Estradiol; Estrogen Receptor alpha; Female; Heme Oxygenase (Decyclizing); Hypertrophy, Left Ventricular; Ovariectomy; Piperidines; Rats, Wistar; Receptors, Adiponectin; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Cardiovascular risk factors and the concentration of asymmetric dimethylarginine.
Topics: Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Middle Aged; Risk Factors | 2020 |
Insulinotropic and antidiabetic effects of β-caryophyllene with l-arginine in type 2 diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Polycyclic Sesquiterpenes; Rats | 2020 |
C-Terminal Domain of the Human Zinc Transporter hZnT8 Is Structurally Indistinguishable from Its Disease Risk Variant (R325W).
Topics: Amino Acid Substitution; Arginine; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Humans; Models, Molecular; Protein Domains; Protein Multimerization; Protein Structure, Secondary; Scattering, Small Angle; Tryptophan; X-Ray Diffraction; Zinc; Zinc Transporter 8 | 2020 |
Plausible diagnostic value of urinary isomeric dimethylarginine ratio for diabetic nephropathy.
Topics: Adult; Aged; Albuminuria; Arginine; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Feasibility Studies; Female; Humans; Male; Middle Aged; Predictive Value of Tests; ROC Curve; Tandem Mass Spectrometry | 2020 |
Characterization and therapeutic efficacy evaluation of glimepiride and L-arginine co-amorphous formulation prepared by supercritical antisolvent process: Influence of molar ratio and preparation methods.
Topics: Administration, Oral; Animals; Arginine; Blood Glucose; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Combinations; Drug Compounding; Drug Liberation; Humans; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Male; Particle Size; Powder Diffraction; Rats; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Streptozocin; Sulfonylurea Compounds; X-Ray Diffraction | 2020 |
Development and Application of Mass Spectroscopy Assays for Nε-(1-Carboxymethyl)-L-Lysine and Pentosidine in Renal Failure and Diabetes.
Topics: Arginine; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Lysine; Mass Spectrometry; Renal Insufficiency; Reproducibility of Results | 2020 |
Modulation of Nitric Oxide Bioavailability Attenuates Ischemia-Reperfusion Injury in Type II Diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reperfusion Injury; Skin; Surgical Flaps | 2021 |
L-Arginine prevents cereblon-mediated ubiquitination of glucokinase and stimulates glucose-6-phosphate production in pancreatic β-cells.
Topics: Adaptor Proteins, Signal Transducing; Arginine; Cell Line; Diabetes Mellitus, Type 2; Glucokinase; Glucose-6-Phosphate; Glutamic Acid; HEK293 Cells; Humans; Insulin Secretion; Insulin-Secreting Cells; Proteolysis; Signal Transduction; Ubiquitin-Protein Ligases; Ubiquitination | 2020 |
ADMA (asymmetric dimethylarginine) and angiogenic potential in patients with type 2 diabetes and prediabetes.
Topics: Adult; Aged; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Neovascularization, Physiologic; Prediabetic State; Solubility; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2021 |
The structural role of osteocalcin in bone biomechanics and its alteration in Type-2 Diabetes.
Topics: Adsorption; Amino Acid Motifs; Amino Acid Sequence; Arginine; Biomechanical Phenomena; Bone and Bones; Bone Diseases, Metabolic; Diabetes Mellitus, Type 2; Durapatite; Humans; Hydrogen Bonding; Molecular Dynamics Simulation; Osteocalcin; Protein Conformation, alpha-Helical; Structure-Activity Relationship; Thermodynamics | 2020 |
Increased Intraplatelet ADMA Level May Promote Platelet Activation in Diabetes Mellitus.
Topics: Adenosine Diphosphate; Adult; Aged; Arginine; Blood Platelets; Calcium; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Platelet Activation; Platelet Aggregation; Risk Factors | 2020 |
Lack of evidence of the correlation between plasma Asymmetrical Dimethylarginine correlation and IMT in type 2 diabetic patients with chronic vascular complication.
Topics: Adult; Aged; Arginine; Atherosclerosis; Carotid Artery, Internal; Carotid Intima-Media Thickness; Case-Control Studies; Chronic Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Middle Aged; Risk Factors; Ultrasonography, Doppler, Color | 2021 |
Abnormalities of the PRMT1-ADMA-DDAH1 metabolism axis and probucol treatment in diabetic patients and diabetic rats.
Topics: Amidohydrolases; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Nitric Oxide; Probucol; Protein-Arginine N-Methyltransferases; Rats; Repressor Proteins | 2021 |
Elevated serum pentosidine is independently associated with the high prevalence of sarcopenia in Chinese middle-aged and elderly men with type 2 diabetes mellitus.
Topics: Aged; Arginine; China; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Geriatric Assessment; Hand Strength; Humans; Lysine; Male; Middle Aged; Prevalence; Risk Assessment; Risk Factors; Sarcopenia | 2021 |
Habitual intake of dietary L-arginine in relation to risk of type 2 diabetes: a prospective study.
Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Diet; Female; Follow-Up Studies; Humans; Incidence; Iran; Male; Prognosis; Prospective Studies; Risk Factors | 2021 |
A Cross-Talk between the Erythrocyte L-Arginine/ADMA/Nitric Oxide Metabolic Pathway and the Endothelial Function in Subjects with Type 2 Diabetes Mellitus.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Citrulline; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Erythrocytes; Female; Humans; Male; Metabolic Networks and Pathways; Middle Aged; Nitric Oxide | 2021 |
HIV-infected persons with type 2 diabetes show evidence of endothelial dysfunction and increased inflammation.
Topics: Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; HIV Infections; Humans; Inflammation; Male; Methylamines; Middle Aged; Risk Factors; Tandem Mass Spectrometry | 2017 |
Association of circulatory asymmetric dimethylarginine (ADMA) with diabetic nephropathy in Asian Indians and its causative role in renal cell injury.
Topics: Adult; Albuminuria; Animals; Arginine; Asian People; Biomarkers; Cell Line; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Fibroblasts; Glomerular Mesangium; Glycated Hemoglobin; Humans; India; Male; Middle Aged; Rats | 2017 |
Physical activity - related changes in ADMA and vWF levels in patients with type 2 diabetes: A preliminary study.
Topics: Adult; Arginine; Cholesterol, HDL; Diabetes Mellitus, Type 2; Exercise; Female; Humans; Male; Middle Aged; von Willebrand Factor | 2017 |
Argatroban Attenuates Diabetic Cardiomyopathy in Rats by Reducing Fibrosis, Inflammation, Apoptosis, and Protease-Activated Receptor Expression.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Fibrosis; Heart; Inflammation; Male; Myocardium; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Proteinase-Activated; Signal Transduction; Sulfonamides | 2017 |
Symmetric and asymmetric dimethylarginine as risk markers of cardiovascular disease, all-cause mortality and deterioration in kidney function in persons with type 2 diabetes and microalbuminuria.
Topics: Adult; Aged; Albuminuria; Arginine; Cardiovascular Diseases; Coronary Disease; Creatinine; Diabetes Mellitus, Type 2; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Risk Factors | 2017 |
Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study.
Topics: Arginine; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucagon-Like Peptide 1; Glucose; Glucose Tolerance Test; Humans; Insulin; Male; Risk Factors | 2018 |
Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.
Topics: Animals; Arginase; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dietary Sucrose; Endothelium, Vascular; Enzyme Inhibitors; Fibrosis; Genetic Predisposition to Disease; Insulin; Male; Metabolic Syndrome; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Obesity; Ornithine; Oxidative Stress; Phenotype; Signal Transduction; Vascular Diseases; Vascular Stiffness; Vasodilation | 2017 |
Urinary Pentosidine levels negatively associates with trabecular bone scores in patients with type 2 diabetes mellitus.
Topics: Absorptiometry, Photon; Aged; Arginine; Biomarkers; Bone Density; Cancellous Bone; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Lumbar Vertebrae; Lysine; Male; Middle Aged; Osteoporotic Fractures; Spinal Fractures | 2018 |
Relation of asymmetrical dimethylarginine levels with renal outcomes in hypertensive patients with and without type 2 diabetes mellitus.
Topics: Aged; Albuminuria; Arginine; Biomarkers; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic | 2018 |
Characterization of vascular dysregulation in meriones shawi after high-calorie diet feeding.
Topics: Animals; Aorta; Arginine; Carbachol; Diabetes Mellitus, Type 2; Diazoxide; Endothelium, Vascular; Energy Intake; Gerbillinae; Hypertension; Insulin; Male; Metabolic Syndrome; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type II; Norepinephrine; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Vasodilation | 2018 |
Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.
Topics: Aging; Animals; Arginine; Bone Density; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Femur; Fractures, Bone; Lysine; Male; Mice; Spectrum Analysis, Raman; X-Ray Microtomography | 2018 |
Arginine Metabolism Is Altered in Adults with A-β + Ketosis-Prone Diabetes.
Topics: Adult; Arginine; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Gastrointestinal Microbiome; Glucose; Glucose Clamp Technique; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Kinetics; Male; Metabolomics; Middle Aged; Nitric Oxide; Ornithine | 2018 |
Arginine Metabolism and A-β + Ketosis-Prone Diabetes.
Topics: Arginine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Ketosis | 2018 |
Association of endothelial dysfunction with cardiovascular risk factors and new-onset diabetes mellitus in patients with hypertension.
Topics: Aged; Arginine; Brazil; C-Reactive Protein; Cardiovascular Diseases; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Nitric Oxide Synthase; Predictive Value of Tests; Prospective Studies; Risk Factors; Triglycerides | 2018 |
Unraveling the compromised biomechanical performance of type 2 diabetes- and Roux-en-Y gastric bypass bone by linking mechanical-structural and physico-chemical properties.
Topics: Animals; Arginine; Biomechanical Phenomena; Bone and Bones; Diabetes Mellitus, Type 2; Female; Fractures, Bone; Gastric Bypass; Glycation End Products, Advanced; Humans; Lysine; Male; Mice; Mice, Obese; Obesity; Skeleton; Tomography, X-Ray Computed; Weight Loss | 2018 |
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O
Topics: Animals; Anthraquinones; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Combinations; Endothelium, Vascular; Insulin Resistance; Male; NADPH Oxidase 4; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2018 |
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction.
Topics: Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Endothelium; Feces; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Inflammation; Kynurenine; Male; Metabolism; Middle Aged; Neopterin; Risk Factors; RNA, Ribosomal, 16S; Tryptophan | 2018 |
Mixed Meal and Intravenous L-Arginine Tests Both Stimulate Incretin Release Across Glucose Tolerance in Man: Lack of Correlation with β Cell Function.
Topics: Administration, Intravenous; Arginine; Biomarkers; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Eating; Enteroendocrine Cells; Gastric Inhibitory Polypeptide; Gastrointestinal Hormones; Glucagon; Glucagon-Like Peptide 1; Humans; Insulin; Insulin-Secreting Cells; Peptide YY; Postprandial Period; Prediabetic State; Time Factors; United States | 2018 |
Changes in arginine are inversely associated with type 2 diabetes: A case-cohort study in the PREDIMED trial.
Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Citrulline; Cohort Studies; Diabetes Mellitus, Type 2; Diet, Fat-Restricted; Diet, Mediterranean; Female; Humans; Incidence; Insulin Resistance; Male; Middle Aged; omega-N-Methylarginine; Ornithine; Risk Factors | 2019 |
Arginase inhibition improves endothelial function in patients with type 2 diabetes mellitus despite intensive glucose-lowering therapy.
Topics: Aged; Arginase; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Endothelium, Vascular; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipids; Male; Middle Aged; Plethysmography; Vasodilation | 2018 |
Urinary sodium-to-potassium ratio and serum asymmetric dimethylarginine levels in patients with type 2 diabetes.
Topics: Adult; Aged, 80 and over; Arginine; Blood Pressure; Carotid Intima-Media Thickness; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Obesity; Potassium; Sodium | 2018 |
Diabetes with heart failure increases methylglyoxal modifications in the sarcomere, which inhibit function.
Topics: Actins; Adult; Animals; Arginine; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glycolysis; Heart Failure; Heart Ventricles; Humans; Lysine; Male; Mice; Middle Aged; Myosins; Pyruvaldehyde; Sarcomeres; Single-Cell Analysis | 2018 |
Inhibitory effect of silibinin on Amadori-albumin in diabetes mellitus: A multi-spectroscopic and biochemical approach.
Topics: Arginine; Circular Dichroism; Diabetes Mellitus, Type 2; Glycosylation; Humans; Lysine; Protective Agents; Serum Albumin, Human; Silybin; Spectrophotometry, Ultraviolet | 2019 |
A correlational study between serum asymmetric dimethylarginine level and impaired glucose tolerance patients associated with obesity.
Topics: Aged; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Male; Middle Aged; Obesity | 2019 |
Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes.
Topics: Adolescent; Age of Onset; Amino Acid Substitution; Animals; Arginine; Child; Chlorocebus aethiops; Cohort Studies; COS Cells; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genome-Wide Association Study; Germany; Homozygote; Humans; Insulin Resistance; Leucine; Male; Pediatric Obesity; Polymorphism, Single Nucleotide; Receptors, Gastrointestinal Hormone | 2019 |
Lack of Durable Improvements in β-Cell Function Following Withdrawal of Pharmacological Interventions in Adults With Impaired Glucose Tolerance or Recently Diagnosed Type 2 Diabetes.
Topics: Adult; Arginine; B-Lymphocytes; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Female; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin Glargine; Insulin Resistance; Liraglutide; Male; Metformin; Middle Aged; Withholding Treatment | 2019 |
Assessment of serum galectin-3, methylated arginine and Hs-CRP levels in type 2 diabetes and prediabetes.
Topics: Adult; Arginine; Biomarkers; Blood Glucose; Blood Proteins; C-Reactive Protein; Diabetes Mellitus, Type 2; Fasting; Female; Galectin 3; Galectins; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin Resistance; Male; Methylation; Middle Aged; Prediabetic State | 2019 |
The role of oxidant stress and gender in the erythrocyte arginine metabolism and ammonia management in patients with type 2 diabetes.
Topics: Ammonia; Arginine; Colorimetry; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Erythrocytes; Female; Humans; Male; Malondialdehyde; Nitric Oxide; Nitrogen; Oxidative Stress; Sex Factors; Spectrophotometry | 2019 |
Arginine and Carnitine Metabolites Are Altered in Diabetic Retinopathy.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Carnitine; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Female; Follow-Up Studies; Humans; Male; Mass Spectrometry; Middle Aged; Visual Acuity | 2019 |
Amino acids and wound healing in people with limb-threatening diabetic foot ulcers.
Topics: Aged; Aged, 80 and over; Amino Acids; Amputation, Surgical; Arginine; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Foot; Female; Hospitalization; Humans; Isoleucine; Leucine; Male; Threonine; Treatment Outcome; Wound Healing | 2019 |
Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo.
Topics: Adult; Age Factors; Aged; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Humans; Hypercholesterolemia; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged; Nitric Oxide | 2013 |
The value of serum asymmetric dimethylarginine levels for the determination of masked hypertension in patients with diabetes mellitus.
Topics: Adult; Arginine; Biomarkers; Blood Pressure Monitoring, Ambulatory; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Fluorescence; Humans; Hypertension; Logistic Models; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Predictive Value of Tests; Prevalence; Risk Factors; Turkey | 2013 |
Asymmetric dimethylarginine predicts decline of glucose tolerance in men with stable coronary artery disease: a 4.5-year follow-up study.
Topics: Adult; Aged; Angina, Stable; Arginine; Diabetes Mellitus, Type 2; Follow-Up Studies; Glucose Intolerance; Glucose Tolerance Test; Humans; Male; Middle Aged; Prediabetic State; Prognosis; Proportional Hazards Models; Risk Factors | 2013 |
Male hypogonadism induced by high fat diet and low dose streptozotocin is mediated by activated endoplasmic reticulum stress and IκBβ and attenuated by argirein and valsartan.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Combinations; Endoplasmic Reticulum Stress; Hypogonadism; I-kappa B Proteins; Male; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal; Streptozocin; Tetrazoles; Valine; Valsartan | 2013 |
[Comparison of non-glucose versus glucose stimulation test in estimating islet β-cell function in individuals with differential glucose tolerance].
Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans; Male; Middle Aged | 2013 |
Plasma levels of advanced glycation endproducts Nε-(carboxymethyl)lysine, Nε-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: the Hoorn and CODAM studies.
Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Lysine; Male; Middle Aged | 2013 |
Increased erythrocytes by-products of arginine catabolism are associated with hyperglycemia and could be involved in the pathogenesis of type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Blood Glucose; Carbon Isotopes; Case-Control Studies; Citrulline; Diabetes Mellitus, Type 2; Endothelial Cells; Erythrocytes; Female; Glycosylation; Hemoglobins; Hemolysis; Humans; Hyperglycemia; Male; Malondialdehyde; Metabolic Networks and Pathways; Middle Aged; Models, Biological; Nitric Oxide; Nitrites; Ornithine; Oxidative Stress; Urea | 2013 |
ON NO--the continuing story of nitric oxide, diabetes, and cardiovascular disease.
Topics: Arginine; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Male; Nitric Oxide | 2013 |
Comment on: Tessari et al. Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo. Diabetes 2013;62:2699-2708.
Topics: Arginine; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Male; Nitric Oxide | 2013 |
Response to comment on: Tessari et al. Roles of insulin, age, and asymmetric dimethylarginine on nitric oxide synthesis in vivo. Diabetes 2013;62:2699-2708.
Topics: Arginine; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Resistance; Male; Nitric Oxide | 2013 |
Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.
Topics: Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Environment; Female; Genotype; Humans; Intermittent Claudication; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors | 2014 |
Administration of heme arginate ameliorates murine type 2 diabetes independently of heme oxygenase activity.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adiponectin; Adipose Tissue; Adiposity; Animals; Arginine; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Heme; Heme Oxygenase (Decyclizing); Hyperglycemia; Inflammation; Insulin-Secreting Cells; Metalloporphyrins; Mice; Pilot Projects | 2013 |
Apparently "low" serum asymmetric dimethylarginine is associated with fasting glucose and tends toward association with type-2 diabetes.
Topics: Adult; Anthropometry; Arginine; Biomarkers; Coronary Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Male; Metabolic Syndrome; Prospective Studies | 2014 |
Assessment of androgen replacement therapy for erectile function in rats with type 2 diabetes mellitus by examining nitric oxide-related and inflammatory factors.
Topics: Androgens; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Electric Stimulation; Erectile Dysfunction; Hormone Replacement Therapy; Interleukin-6; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Penile Erection; Penis; Rats, Long-Evans; Testosterone; Tumor Necrosis Factor-alpha | 2014 |
Assessment of beta-cell function in young patients with type 2 diabetes: arginine-stimulated insulin secretion may reflect beta-cell reserve.
Topics: Administration, Intravenous; Adult; Arginine; C-Peptide; Cell Physiological Phenomena; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Reproducibility of Results | 2014 |
An assessment of correlation between serum asymmetric dimethylarginine and glycated haemoglobin in patients with type 2 diabetes mellitus.
Topics: Arginine; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Hyperglycemia; Male; Middle Aged; Nephelometry and Turbidimetry; Oxidative Stress | 2014 |
Arg972 insulin receptor substrate-1 polymorphism and risk and severity of Alzheimer's disease.
Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Arginine; China; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin Receptor Substrate Proteins; Male; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Retrospective Studies | 2014 |
Insulin secretory function: not a simple measurement.
Topics: Arginine; C-Peptide; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin-Secreting Cells; Male | 2014 |
Relationship of polymorphisms in the cholesteryl ester transport protein gene R451Q with coronary heart disease and diabetes in Uyghur and Han Chinese.
Topics: Adult; Aged; Arginine; Asian People; Case-Control Studies; Cholesterol Ester Transfer Proteins; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Gene Frequency; Glutamine; Humans; Lipids; Male; Middle Aged; Polymorphism, Single Nucleotide | 2014 |
L-arginine catabolism is driven mainly towards nitric oxide synthesis in the erythrocytes of patients with type 2 diabetes at first clinical onset.
Topics: Arginase; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Electrophoresis, Capillary; Erythrocytes; Female; Glycated Hemoglobin; Humans; Hypertension; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites | 2015 |
Potential of birds to serve as pathology-free models of type 2 diabetes, part 2: do high levels of carbonyl-scavenging amino acids (e.g., taurine) and low concentrations of methylglyoxal limit the production of advanced glycation end-products?
Topics: Albumins; Animals; Arginine; Birds; Diabetes Mellitus, Type 2; Disease Models, Animal; Fructosamine; Glucose; Glycation End Products, Advanced; Lysine; Maillard Reaction; Pyruvaldehyde; Taurine | 2014 |
Relation of asymmetric dimethylarginine levels to macrovascular disease and inflammation markers in type 2 diabetic patients.
Topics: Aged; Arginine; Atherosclerosis; Biomarkers; Blood Sedimentation; C-Reactive Protein; Carotid Intima-Media Thickness; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Fibrinogen; Homocysteine; Humans; Inflammation Mediators; Male; Middle Aged; Regression Analysis; Systemic Vasculitis; Up-Regulation | 2014 |
Involvement of increased endogenous asymmetric dimethylarginine in the hepatic endoplasmic reticulum stress of type 2 diabetic rats.
Topics: Animals; Arginine; Cell Line, Tumor; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Liver; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2014 |
Effects of oleuropein in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium, Vascular; Hypertension, Renal; Iridoid Glucosides; Iridoids; Male; Molecular Structure; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2014 |
Circulating dickkopf-1 in diabetes mellitus: association with platelet activation and effects of improved metabolic control and low-dose aspirin.
Topics: Aged; Arginine; Aspirin; Biomarkers; Cardiovascular Diseases; Case-Control Studies; CD40 Ligand; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Platelet Activation; Platelet Aggregation Inhibitors; Thromboxane B2; Wnt Signaling Pathway | 2014 |
PTEN deletion in pancreatic α-cells protects against high-fat diet-induced hyperglucagonemia and insulin resistance.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Diet, High-Fat; Female; Glucagon; Glucagon-Secreting Cells; Hyperglycemia; Insulin Resistance; Insulin-Secreting Cells; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; RNA, Small Interfering; Signal Transduction | 2015 |
Anti-pruritic activity of pioglitazone on serotonin-induced scratching in mice: possible involvement of PPAR-gamma receptor and nitric oxide.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pioglitazone; PPAR gamma; Serotonin; Thiazolidinediones | 2014 |
In vitro anti-inflammatory effects of citrulline on peritoneal macrophages in Zucker diabetic fatty rats.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Blood Glucose; Citrulline; Diabetes Mellitus, Type 2; Interleukin-6; Macrophages, Peritoneal; Male; Nitric Oxide; Obesity; Rats; Rats, Zucker; Tumor Necrosis Factor-alpha | 2015 |
Effects of acute exercise on pancreatic endocrine function in subjects with type 2 diabetes.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Exercise; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucose Clamp Technique; Humans; Hyperglycemia; Infusions, Intravenous; Injections; Insulin; Insulin Secretion; Male; Pancreas; Treatment Outcome | 2015 |
Asymmetric dimethylarginine and long-term adverse cardiovascular events in patients with type 2 diabetes: relation with the glycemic control.
Topics: Aged; Aged, 80 and over; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Middle Aged; Prognosis; Prospective Studies; Risk Assessment; Risk Factors | 2014 |
Glycated peptides are associated with the variability of endothelial dysfunction in the cerebral vessels and the kidney in type 2 diabetes mellitus patients: a cross-sectional study.
Topics: Aged; Albuminuria; Arginine; Biomarkers; Breath Holding; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Endothelium, Vascular; Female; Glomerular Filtration Rate; Glycation End Products, Advanced; Humans; Kidney; Male; Middle Aged; Outpatient Clinics, Hospital; Romania; Severity of Illness Index; Vasculitis, Central Nervous System | 2015 |
Accelerated onset of senescence of endothelial progenitor cells in patients with type 2 diabetes mellitus: role of dimethylarginine dimethylaminohydrolase 2 and asymmetric dimethylarginine.
Topics: Amidohydrolases; Arginine; Cellular Senescence; Diabetes Mellitus, Type 2; Endothelial Progenitor Cells; Female; Humans; Male; Middle Aged; Sirtuin 1 | 2015 |
Lymphatic vascular integrity is disrupted in type 2 diabetes due to impaired nitric oxide signalling.
Topics: Animals; Arginine; Capillary Permeability; Diabetes Mellitus, Type 2; Female; Lymphatic Vessels; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Phosphodiesterase 3 Inhibitors; Signal Transduction | 2015 |
Asymmetric dimethylarginine is negatively correlated with hyperglycemia in children.
Topics: Adolescent; Arginine; Biomarkers; Body Mass Index; Cardiovascular Diseases; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Cardiomyopathies; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hyperglycemia; Japan; Male; Pediatric Obesity; Risk | 2015 |
The relationship between serum asymmetric dimethylarginine levels and subjective sleep quality in normotensive patients with type 2 diabetes mellitus.
Topics: Adult; Arginine; Biomarkers; Cardiovascular Diseases; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Risk Factors; Sleep; Sleep Wake Disorders; Surveys and Questionnaires | 2015 |
LC-MS/MS for the simultaneous determination of polar endogenous ADMA and CML in plasma and urine from diabetics.
Topics: Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Linear Models; Lysine; Retrospective Studies; Tandem Mass Spectrometry | 2015 |
The effect of nephropathy on plasma sphingosine 1-phosphate concentrations in patients with type 2 diabetes.
Topics: Albuminuria; Apolipoproteins; Apolipoproteins M; Arginine; Biological Transport; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Lipocalins; Lysophospholipids; Male; Middle Aged; Sphingosine; Triglycerides | 2015 |
Site specific modification of the human plasma proteome by methylglyoxal.
Topics: Arginine; Binding Sites; Biomarkers; Blood Proteins; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; High-Throughput Screening Assays; Humans; Male; Peptide Mapping; Protein Binding; Protein Carbonylation; Protein Processing, Post-Translational; Proteomics; Pyruvaldehyde; Serum Albumin; Serum Albumin, Human; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
A Single Amino Acid Mutation (R104P) in the E/DRY Motif of GPR40 Impairs Receptor Function.
Topics: Amino Acid Motifs; Arginine; Calcium; Diabetes Mellitus, Type 2; Glucose; HEK293 Cells; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Mutation; Receptors, G-Protein-Coupled | 2015 |
Skin collagen pentosidine and fluorescence in diabetes were predictors of retinopathy progression and creatininemia increase already 6years after punch-biopsy.
Topics: Adult; Albuminuria; Arginine; Biomarkers; Biopsy; Case-Control Studies; Collagen; Creatinine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Disease Progression; Female; Fluorescence; Humans; Longitudinal Studies; Lysine; Male; Middle Aged; Skin; Spectrometry, Fluorescence | 2016 |
[CLINICAL AND LABORATORY FEATURES OF ACUTE PANCREATITIS BILIARY ETIOLOGY COURSE IN PATIENTS WITH DIABETES MELLITUS].
Topics: Adenosine Deaminase; Adult; Aged; Arginine; Biomarkers; Case-Control Studies; Common Bile Duct; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hypoxia; Liver; Liver Failure, Acute; Male; Middle Aged; Pancreas; Pancreatitis, Acute Necrotizing; Severity of Illness Index; Xanthine Dehydrogenase; Xanthine Oxidase | 2015 |
Characteristics of blood glucose excursions in type 2 diabetes mellitus patients with three different Traditional Chinese Medicine syndromes.
Topics: Adult; Aged; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Yin Deficiency; Young Adult | 2015 |
Lack of association between the insulin receptor substrates-1 Gly972Arg polymorphism and type-2 diabetes mellitus among Saudis from Eastern Saudi Arabia.
Topics: Adult; Aged; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Glycine; Humans; Insulin Receptor Substrate Proteins; Male; Middle Aged; Polymorphism, Single Nucleotide; Saudi Arabia | 2015 |
ADMA: a specific biomarker for pathologic progress in diabetic microvascular complications?
Topics: Adult; Aged; Area Under Curve; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Logistic Models; Lysine; Male; Middle Aged; Odds Ratio; Prediabetic State; ROC Curve; Tandem Mass Spectrometry | 2016 |
Serum advanced glycation endproducts are associated with left ventricular dysfunction in normal glucose metabolism but not in type 2 diabetes: The Hoorn Study.
Topics: Aged; Arginine; Biomarkers; Blood Glucose; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Echocardiography; Female; Glycation End Products, Advanced; Humans; Linear Models; Lysine; Male; Middle Aged; Myocardial Contraction; Netherlands; Predictive Value of Tests; Prognosis; Risk Assessment; Risk Factors; Ventricular Dysfunction, Left; Ventricular Function, Left | 2016 |
Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction.
Topics: Aged; Arginase; Arginine; Biomarkers; Case-Control Studies; Citrulline; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Forearm; Humans; Male; Middle Aged; Nitric Oxide Synthase; Ornithine; Up-Regulation; Vasodilation | 2016 |
Evidence for the involvement of neuropeptide Y in the antidepressant effect of imipramine in type 2 diabetes.
Topics: Animals; Antidepressive Agents, Tricyclic; Arginine; Blood Glucose; Central Amygdaloid Nucleus; Depression; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Imipramine; Male; Mice; Motor Activity; Neuropeptide Y; Nucleus Accumbens; Receptors, Neuropeptide Y; Septal Nuclei; Streptozocin | 2016 |
Serum asymmetric dimethylarginine and arginine levels predict microvascular and macrovascular complications in type 2 diabetes mellitus.
Topics: Adolescent; Adult; Aged; Arginine; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cross-Sectional Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; Oxidative Stress; Prognosis; Prospective Studies; Risk Factors; Young Adult | 2017 |
Standardized Mixed-Meal Tolerance and Arginine Stimulation Tests Provide Reproducible and Complementary Measures of β-Cell Function: Results From the Foundation for the National Institutes of Health Biomarkers Consortium Investigative Series.
Topics: Adult; Arginine; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Meals; Middle Aged; National Institutes of Health (U.S.); Prediabetic State; Reference Standards; Reproducibility of Results; United States | 2016 |
The effects of n-3 long-chain polyunsaturated fatty acid supplementation on AGEs and sRAGE in type 2 diabetes mellitus.
Topics: Aged; Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Dietary Supplements; Fasting; Fatty Acids, Omega-3; Female; Gene Expression Regulation; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lysine; Male; Middle Aged; NF-kappa B; Receptor for Advanced Glycation End Products; Signal Transduction; Waist Circumference | 2016 |
Asymmetrical dimethyl arginine in type 2 diabetic patients with coronary artery disease.
Topics: Adult; Arginine; Blood Glucose; Case-Control Studies; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Triglycerides | 2016 |
Skin Autofluorescence and Pentosidine Are Associated With Aortic Stiffening: The Maastricht Study.
Topics: Adult; Aged; Analysis of Variance; Arginine; Blood Pressure; Cardiovascular Diseases; Chi-Square Distribution; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Glucose; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Linear Models; Lysine; Middle Aged; Optical Imaging; Prospective Studies; Pulse Wave Analysis; Skin; Vascular Stiffness | 2016 |
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2.
Topics: Aminoisobutyric Acids; Animals; Arginine; Cardiovascular Diseases; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Risk; RNA, Small Interfering; Transaminases | 2016 |
Plasma Levels of Pentosidine, Carboxymethyl-Lysine, Soluble Receptor for Advanced Glycation End Products, and Metabolic Syndrome: The Metformin Effect.
Topics: Adult; Arginine; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Humans; Hypoglycemic Agents; Lysine; Male; Metabolic Syndrome; Metformin; Middle Aged; Prognosis; Receptor for Advanced Glycation End Products | 2016 |
Impaired osteogenic differentiation and enhanced cellular receptor of advanced glycation end products sensitivity in patients with type 2 diabetes.
Topics: Apoptosis; Arginine; Biomarkers; Cell Differentiation; Cell Membrane; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Gene Expression Profiling; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Osteogenesis; Receptor for Advanced Glycation End Products; Risk Factors | 2017 |
Genetic polymorphisms in extracellular superoxide dismutase Leu53Leu, Arg213Gly, and Ala40Thr and susceptibility to type 2 diabetes mellitus.
Topics: Adult; Alanine; Arginine; Asian People; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Male; Middle Aged; Polymorphism, Single Nucleotide; Regression Analysis; Superoxide Dismutase; Threonine | 2016 |
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Topics: 5-Hydroxytryptophan; Aged; Arginine; Blood Glucose; C-Peptide; Carbon Radioisotopes; Case-Control Studies; Cell Differentiation; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Disease Progression; Female; Glucose; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Magnetic Resonance Imaging; Male; Middle Aged; Organ Size; Positron Emission Tomography Computed Tomography | 2017 |
Vitreous advanced glycation endproducts and α-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Retinal Detachment | 2017 |
Glycated albumin as an improved indicator of glycemic control in hemodialysis patients with type 2 diabetes based on fasting plasma glucose and oral glucose tolerance test.
Topics: Aged; Area Under Curve; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Renal Dialysis; Serum Albumin | 2009 |
Increased serum endogenous secretory receptor for advanced glycation end-product (esRAGE) levels in type 2 diabetic patients with decreased renal function.
Topics: Aged; Arginine; Carotid Arteries; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Lysine; Male; Middle Aged; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Renal Dialysis; Severity of Illness Index; Tunica Intima; Tunica Media; Ultrasonography | 2008 |
Impact of the endothelial nitric oxide synthase gene G894T polymorphism on renal endothelial function in patients with type 2 diabetes.
Topics: Alleles; Analysis of Variance; Arginine; Ascorbic Acid; Body Mass Index; Cholesterol, HDL; Diabetes Mellitus, Type 2; Endothelium; Female; Genotype; Guanine; Hemodynamics; Homozygote; Humans; Kidney; Male; Middle Aged; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Polymorphism, Single Nucleotide; Renal Plasma Flow; Thymine; Triglycerides | 2008 |
Impaired glucose-stimulated insulin secretion in the GK rat is associated with abnormalities in islet nitric oxide production.
Topics: Animals; Arginine; Colforsin; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2008 |
Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome.
Topics: Animals; Arginine; Basal Metabolism; Blood Glucose; Blood Pressure; Body Weight; Chromosome Mapping; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretion; Islets of Langerhans; Lipids; Obesity; Quantitative Trait Loci; Rats; Rats, Inbred Strains | 2008 |
Biomarkers of oxidative stress and endothelial dysfunction in glucose intolerance and diabetes mellitus.
Topics: Arginine; Biomarkers; Body Mass Index; Diabetes Mellitus, Type 2; Endothelium; Female; Glucose Intolerance; Glutathione; Hexosaminidases; Humans; Lipids; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress | 2008 |
Plasma levels of asymmetric dimethylarginine in premature neonates: its possible involvement in developmental programming of chronic diseases.
Topics: Arginine; Cardiovascular Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Metabolic Syndrome | 2009 |
Relation between human vasopressin 1a gene variance, fat intake, and diabetes.
Topics: Alleles; Animals; Arginine; Blood Glucose; Body Mass Index; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dietary Fats; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Hypertriglyceridemia; Male; Mice; Mice, Knockout; Middle Aged; Obesity; Polymorphism, Single Nucleotide; Prevalence; Prospective Studies; Receptors, Vasopressin; Triglycerides | 2009 |
The polymorphism Arg585Gln in the gene of the sterol regulatory element binding protein-1 (SREBP-1) is not a determinant of ketosis prone type 2 diabetes (KPD) in Africans.
Topics: Adult; Amino Acid Substitution; Arginine; Black People; C-Peptide; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glutamine; Humans; Lipids; Male; Middle Aged; Polymorphism, Genetic; Sterol Regulatory Element Binding Protein 1 | 2009 |
Asymmetric dimethylarginine is closely associated with the development and progression of nephropathy in patients with type 2 diabetes.
Topics: Adult; Aged; Albuminuria; Arginine; Biomarkers; Cohort Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Japan; Male; Middle Aged; Nitric Oxide Synthase; Prognosis; Proportional Hazards Models; Prospective Studies | 2009 |
Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced beta-cell endoplasmic reticulum stress.
Topics: Adaptation, Physiological; Amyloid; Animals; Arginine; Diabetes Mellitus, Type 2; Dietary Fats; Endoplasmic Reticulum; Humans; Hyperglycemia; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Islet Amyloid Polypeptide; Islets of Langerhans; Obesity; Rats; Rats, Sprague-Dawley; Rats, Transgenic | 2009 |
Alterations in L-arginine and inflammatory markers in type 2 diabetic patients with and without microalbuminuria.
Topics: Albuminuria; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Neopterin | 2009 |
Association of TRB3 gene Q84R polymorphism with type 2 diabetes mellitus in Chinese population.
Topics: Adult; Aged; Amino Acid Substitution; Arginine; Case-Control Studies; Cell Cycle Proteins; China; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Linkage; Genetics, Population; Glutamic Acid; Humans; Insulin Resistance; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Repressor Proteins | 2009 |
Relationship between cerebral arterial pulsatility and carotid intima media thickness in diabetic and non-diabetic patients with non-alcoholic fatty liver disease.
Topics: Aged; Arginine; Basilar Artery; Carotid Arteries; Diabetes Mellitus, Type 2; Fatty Liver; Female; Humans; Male; Middle Aged; Pulsatile Flow; Tunica Intima; Tunica Media; Ultrasonography | 2009 |
Plasma apelin and asymmetric dimethylarginine levels in type 2 diabetic patients with diabetic retinopathy.
Topics: Aged; Albuminuria; Apelin; Arginine; Blood Glucose; Blood Pressure; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Fasting; Female; Humans; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Oxidative Stress; Waist-Hip Ratio | 2009 |
The second-meal phenomenon in type 2 diabetes.
Topics: Arginine; Blood Glucose; C-Peptide; Catecholamines; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Feeding Behavior; Glucagon; Humans; Insulin; Postprandial Period | 2009 |
Pentosidine and increased fracture risk in older adults with type 2 diabetes.
Topics: Aged; Arginine; Bone Density; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Fractures, Bone; Humans; Incidence; Lysine; Male; Prevalence; Risk Factors; Spinal Fractures | 2009 |
Beneficial endocrine but adverse exocrine effects of sitagliptin in the human islet amyloid polypeptide transgenic rat model of type 2 diabetes: interactions with metformin.
Topics: Amyloid; Animals; Animals, Genetically Modified; Arginine; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Hypoglycemic Agents; Islet Amyloid Polypeptide; Islets of Langerhans; Metformin; Pyrazines; Rats; Rats, Sprague-Dawley; Sitagliptin Phosphate; Triazoles | 2009 |
Impaired PRMT1 activity in the liver and pancreas of type 2 diabetic Goto-Kakizaki rats.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Gene Deletion; Gene Expression; Gluconeogenesis; Insulin; Insulin Secretion; Insulin-Secreting Cells; Liver; Methylation; Pancreas; Protein-Arginine N-Methyltransferases; Rats; Rats, Mutant Strains; Rats, Wistar; RNA, Small Interfering | 2009 |
Pancreatic function of spontaneously diabetic torii rats in pre-diabetic stage.
Topics: Animals; Arginine; Benzoates; Body Weight; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Glucagon; Glucagon-Like Peptide 1; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Obesity; Organ Culture Techniques; Pancreas; Peptide Fragments; Rats; Rats, Sprague-Dawley; Tolbutamide | 2009 |
Diabetic retinopathy is associated with elevated serum asymmetric and symmetric dimethylarginines.
Topics: Anthracenes; Arginine; Biomarkers; Blindness; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Models, Molecular; Multivariate Analysis; Propane | 2009 |
Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes.
Topics: Arginine; Base Sequence; Calpain; Case-Control Studies; Diabetes Mellitus, Type 2; DNA Primers; Glucose; Glyburide; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Pancreatic Neoplasms; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2009 |
Association of Gly972Arg polymorphism of IRS1 gene with type 2 diabetes mellitus in lean participants of a national health survey in Mexico: a candidate gene study.
Topics: Aged; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Health Surveys; Humans; Insulin Receptor Substrate Proteins; Logistic Models; Mexico; Middle Aged; Polymorphism, Single Nucleotide | 2010 |
Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes.
Topics: Age of Onset; Aged; Aged, 80 and over; Albuminuria; Arginine; Blood Glucose; Bone Density; Creatinine; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Lysine; Male; Middle Aged; Postmenopause; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Regression Analysis; Risk Factors; Spinal Fractures | 2009 |
The relation of ADMA and apelin to endothelial dysfunction and angiogenesis in patients with type 2 diabetes mellitus.
Topics: Apelin; Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Retinopathy; Endothelium, Vascular; Humans; Intercellular Signaling Peptides and Proteins; Life Style; Neovascularization, Pathologic | 2009 |
LMNA gene mutation search in Polish patients: new features of the heterozygous Arg482Gln mutation phenotype.
Topics: Amino Acid Substitution; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; DNA Mutational Analysis; Female; Genetic Association Studies; Glutamine; Heterozygote; Humans; Insulin Resistance; Lamin Type A; Lipodystrophy, Familial Partial; Male; Middle Aged; Point Mutation; Poland; Pulmonary Fibrosis; Skinfold Thickness | 2009 |
Critical evaluation of toxic versus beneficial effects of methylglyoxal.
Topics: Animals; Arginine; Cataract; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Delivery Systems; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidative Stress; Protein Conformation; Protein Folding; Pyruvaldehyde; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serum Albumin | 2009 |
Evaluation of beta cell dysfunction by mixed meal tolerance test and oral L-arginine in patients with newly diagnosed type 2 diabetes mellitus.
Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Eating; Female; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Time Factors | 2009 |
Impaired beta-cell sensitivity to glucose and maximal insulin secretory capacity in adolescents with type 2 diabetes.
Topics: Adolescent; Arginine; Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Fasting; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male | 2010 |
Inhibition of thrombin action ameliorates insulin resistance in type 2 diabetic db/db mice.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Adipose Tissue; Animals; Anticoagulants; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Drug Tolerance; Factor VII; Humans; Insulin; Insulin Resistance; Interleukin-6; Macrophages; Mice; Mice, Inbred Strains; Pipecolic Acids; Platelet Aggregation Inhibitors; Receptors, CCR2; Reverse Transcriptase Polymerase Chain Reaction; RNA; Sulfonamides; Thrombin | 2010 |
Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin.
Topics: Aged; Apolipoprotein B-100; Arginine; Blood Pressure; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Lipoproteins; Lipoproteins, LDL; Male; Metformin; Middle Aged; Reference Values | 2010 |
Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase.
Topics: Animals; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelial Cells; Glycation End Products, Advanced; Hypoglycemic Agents; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Vascular Diseases; Vasodilation; Vasodilator Agents | 2010 |
Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes.
Topics: Aged; Amidohydrolases; Arginine; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Genotype; Haplotypes; Humans; Male; Mass Spectrometry; Middle Aged; Polymorphism, Genetic | 2010 |
[Evaluation of the impact of genetic background on islet beta-cell function of normal glucose tolerance and newly diagnosed diabetic patients by L-arginine stimulation test.].
Topics: Arginine; Diabetes Mellitus, Type 2; Genetic Background; Glucose; Glucose Tolerance Test; Humans; Insulin; Islets of Langerhans | 2010 |
ADMA is a correlate of insulin resistance in early-stage diabetes independent of hs-CRP and body adiposity.
Topics: Adiposity; Adult; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Case-Control Studies; Cholesterol, HDL; Cholesterol, LDL; Creatinine; Diabetes Mellitus, Type 2; Fasting; Homeostasis; Humans; Inflammation; Insulin Resistance; Male; Middle Aged; Triglycerides | 2010 |
POLG1 p.R722H mutation associated with multiple mtDNA deletions and a neurological phenotype.
Topics: Aged, 80 and over; Arginine; Brain; Deglutition Disorders; Diabetes Mellitus, Type 2; Disease Progression; DNA Polymerase gamma; DNA-Directed DNA Polymerase; DNA, Mitochondrial; Histidine; Humans; Male; Mitochondrial Diseases; Mutation; Ophthalmoplegia; Phenotype | 2010 |
Nitric oxide synthesis is reduced in subjects with type 2 diabetes and nephropathy.
Topics: Aged; Amino Acids; Arginine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glomerular Filtration Rate; Humans; Male; Middle Aged; Nitric Oxide; Reference Values | 2010 |
Relationships between dimethylarginine and the presence of vertebral fractures in type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Bone Density; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Risk Factors; Spinal Fractures | 2010 |
Genetic polymorphisms in organic cation transporter 1 (OCT1) in Chinese and Japanese populations exhibit altered function.
Topics: Aged; Arginine; Biological Transport, Active; Biotinylation; Blotting, Western; Cell Line; China; Diabetes Mellitus, Type 2; DNA; Female; Flow Cytometry; Genetic Variation; Genotype; Green Fluorescent Proteins; Humans; Hypoglycemic Agents; Japan; Kinetics; Male; Metformin; Middle Aged; Organic Cation Transporter 1; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Sequence Alignment | 2010 |
Chitotriosidase activity predicts endothelial dysfunction in type-2 diabetes mellitus.
Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Endothelium; Female; Hexosaminidases; Humans; Male; Middle Aged; Young Adult | 2010 |
Asymmetric dimethylarginine as a risk factor for cardiovascular disease in Japanese patients with type 2 diabetes mellitus.
Topics: Aged; Arginine; Asian People; Cardiovascular Diseases; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Regression Analysis; Risk Factors | 2011 |
Arginase 1 contributes to diminished coronary arteriolar dilation in patients with diabetes.
Topics: Acetylcholine; Aged; Arginase; Arginine; Arterioles; Coronary Vessels; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; NG-Nitroarginine Methyl Ester; Nitroprusside; Up-Regulation; Vasodilation; Vasodilator Agents | 2011 |
Arginase inhibition restores in vivo coronary microvascular function in type 2 diabetic rats.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Flow Velocity; Blood Glucose; Coronary Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Enzyme Inhibitors; Insulin; Male; Microvessels; Nitrites; omega-N-Methylarginine; Rats; Rats, Wistar | 2011 |
The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study.
Topics: Aged; Amidohydrolases; Analysis of Variance; Arginine; Biomarkers; Blood Glucose; Cardiovascular Diseases; Case-Control Studies; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cohort Studies; Coronary Angiography; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genetic Predisposition to Disease; Haplotypes; Humans; Insulin; Insulin Resistance; Kaplan-Meier Estimate; Linear Models; Linkage Disequilibrium; Logistic Models; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Genetic; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Taiwan | 2011 |
Pancreatic beta-cell failure in obese mice with human-like CMP-Neu5Ac hydroxylase deficiency.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Glucose; Glucose Intolerance; Hyperglycemia; Insulin-Secreting Cells; Mice; Mice, Knockout; Mice, Obese; Mixed Function Oxygenases; Mutation; Obesity | 2011 |
Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography.
Topics: Aged; Arginine; Cardiovascular Diseases; Chromatography; Citrulline; Coronary Angiography; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; Models, Biological; Nitric Oxide; Ornithine; Proportional Hazards Models; Vascular Cell Adhesion Molecule-1 | 2011 |
Quantitation of L-arginine and asymmetric dimethylarginine in human plasma by LC-selective ion mode-MS for Type 2 diabetes mellitus study.
Topics: Adult; Aged; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Middle Aged | 2011 |
Dimethylarginines in patients with type 2 diabetes mellitus: relation with the glycaemic control.
Topics: Arginine; Blood Glucose; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycemic Index; Humans; Male; Prognosis | 2011 |
Levels of soluble advanced glycation end product-receptors and other soluble serum markers as indicators of diabetic neuropathy in the foot.
Topics: Aged; Arginine; Biomarkers; Diabetes Mellitus, Type 2; Diabetic Foot; Diabetic Neuropathies; Glycated Hemoglobin; Humans; Male; Middle Aged; Nitric Oxide; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility | 2011 |
Ascorbic acid: what do we really no?
Topics: Arginine; Ascorbic Acid; Body Temperature; Diabetes Mellitus, Type 2; Female; Heat Stress Disorders; Humans; Male; Microcirculation; Nitric Oxide; Renal Insufficiency, Chronic; Skin; Vasodilation | 2011 |
An association between TRP64ARG polymorphism of the B3 adrenoreceptor gene and some metabolic disturbances.
Topics: Adult; Aged; Alleles; Arginine; Diabetes Mellitus, Type 2; Female; Genetic Association Studies; Humans; Kyrgyzstan; Male; Metabolic Syndrome; Middle Aged; Obesity; Polymorphism, Genetic; Receptors, Adrenergic, beta-3; Tryptophan | 2011 |
Arginine availability modulates arginine metabolism and TNFα production in peritoneal macrophages from Zucker Diabetic Fatty rats.
Topics: Animals; Arginase; Arginine; Cells, Cultured; Diabetes Mellitus, Type 2; Down-Regulation; Interleukin-6; Macrophages, Peritoneal; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Obesity; Osmolar Concentration; Rats; Rats, Zucker; Tumor Necrosis Factor-alpha; Up-Regulation | 2012 |
Changes of skin temperature of parts of the body and serum asymmetric dimethylarginine (ADMA) in type-2 diabetes mellitus Indian patients.
Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; India; Infrared Rays; Male; Microcirculation; Middle Aged; Risk; Risk Assessment; Skin Temperature; Temperature; Thermography | 2011 |
Endothelial dysfunction in type 2 diabetes.
Topics: Arginine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Ischemia; Male; Muscles; Nitroglycerin; Vasodilation | 2012 |
Correlation between plasma pentosidine concentrations and retinal hemodynamics in patients with type 2 diabetes.
Topics: Arginine; Blood Flow Velocity; Blood Glucose; Body Constitution; Cholesterol; Cross-Linking Reagents; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Hemodynamics; Humans; Laser-Doppler Flowmetry; Lysine; Male; Middle Aged; Prospective Studies; Retinal Artery | 2012 |
The dual behavior of heat shock protein 70 and asymmetric dimethylarginine in relation to serum CRP levels in type 2 diabetes.
Topics: Adult; Arginine; C-Reactive Protein; Case-Control Studies; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; HSP70 Heat-Shock Proteins; Humans; Inflammation Mediators; Male; Middle Aged; Nitric Oxide | 2012 |
The effect of oral L-arginine supplementation on fasting glucose, HbA1c, nitric oxide and total antioxidant status in diabetic patients with atherosclerotic peripheral arterial disease of lower extremities.
Topics: Antioxidants; Arginine; Atherosclerosis; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; Fasting; Female; Glycated Hemoglobin; Humans; Lower Extremity; Male; Middle Aged; Nitric Oxide; Peripheral Arterial Disease; Regional Blood Flow | 2012 |
A novel missense mutation in the signal peptide of the human POMC gene: a possible additional link between early-onset type 2 diabetes and obesity.
Topics: Animals; Arginine; Cell Line, Tumor; Coronary Disease; Diabetes Mellitus, Type 2; Female; Genetic Loci; Glycine; Heterozygote; Humans; Hypertension; Insulin-Secreting Cells; Mice; Middle Aged; Mutation, Missense; Obesity; Pedigree; Pro-Opiomelanocortin; Protein Sorting Signals; RNA Folding; RNA, Messenger | 2012 |
Delivery of two-step transcription amplification exendin-4 plasmid system with arginine-grafted bioreducible polymer in type 2 diabetes animal model.
Topics: Animals; Arginine; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; DNA; Drug Carriers; Exenatide; Gene Expression; Genetic Therapy; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Peptides; Plasmids; Polymers; Transcription, Genetic; Venoms | 2012 |
Relationship between plasma asymmetric dimethylarginine level and autonomic dysfunction in diabetic patients.
Topics: Administration, Oral; Arginine; Autonomic Nervous System Diseases; Case-Control Studies; Diabetes Mellitus, Type 2; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged | 2012 |
[Glucose tolerance test, glucagon stimulation test, arginine stimulation test].
Topics: Arginine; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans | 2012 |
Arginine-supplemented enteral nutrition in critically ill diabetic and obese rats: a dose-ranging study evaluating nutritional status and macrophage function.
Topics: Amino Acids; Animals; Arginine; Critical Illness; Cytokines; Diabetes Mellitus, Type 2; Dietary Supplements; Dose-Response Relationship, Drug; Enteral Nutrition; Macrophages, Peritoneal; Male; Nutritional Status; Obesity; Rats; Rats, Zucker | 2013 |
Pentosidine as a biomarker for microvascular complications in type 2 diabetic patients.
Topics: Aged; Arginine; Biomarkers; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycation End Products, Advanced; Humans; Hyperlipidemias; Hypertension; Lysine; Male; Microvessels; Middle Aged; Prospective Studies; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Severity of Illness Index; Up-Regulation | 2013 |
The importance of L-arginine metabolism modulation in diabetic patients with distal symmetric polyneuropathy.
Topics: Aged; Arginase; Arginine; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Electrodiagnosis; Female; Fructosamine; Glycated Hemoglobin; Humans; Male; Methylation; Middle Aged; Nitrates; Nitrites; S-Nitrosothiols; Tyrosine | 2013 |
Arginine-containing tripeptide Pro-Arg-Gly is involved in the regulation of the function of anticoagulation and insular systems under persistent hyperglycemia.
Topics: Administration, Intranasal; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptides; Factor XII; Fibrinolysis; Fibrinolytic Agents; Glucose; Male; Oligopeptides; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Rats; Tissue Plasminogen Activator | 2012 |
Chronic renal impairment and DDAH2-1151 A/C polymorphism determine ADMA levels in type 2 diabetic subjects.
Topics: Aged; Amidohydrolases; Arginine; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Follow-Up Studies; Humans; Kidney Function Tests; Male; Middle Aged; Nitric Oxide; Polymorphism, Genetic; Prognosis; Renal Insufficiency, Chronic; Risk Factors | 2013 |
Asymmetric dimethylarginine and carotid atherosclerosis in Type 2 diabetes mellitus.
Topics: Adult; Aged; Arginine; Carotid Artery Diseases; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Prognosis | 2012 |
ADMA, SDMA and L-arginine/ADMA ratio but not DDAH genetic polymorphisms are reliable predictors of diabetic nephropathy progression as identified by competing risk analysis.
Topics: Adult; Aged; Amidohydrolases; Arginine; Cross-Sectional Studies; Czech Republic; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methylation; Middle Aged; Multivariate Analysis; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Reproducibility of Results; Risk Factors | 2012 |
Arginase inhibition improves endothelial function in patients with coronary artery disease and type 2 diabetes mellitus.
Topics: Aged; Arginase; Arginine; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Forearm; Humans; Male; Middle Aged; Nitric Oxide; Vasodilation | 2012 |
Asymmetric dimethylarginine plasma levels and endothelial function in newly diagnosed type 2 diabetic patients.
Topics: Arginine; Blood Pressure; Case-Control Studies; Diabetes Complications; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Risk Factors | 2012 |
The Arg92Cys colipase polymorphism impairs function and secretion by increasing protein misfolding.
Topics: Arginine; Colipases; Cysteine; Diabetes Mellitus, Type 2; Dietary Fats; Enzyme Stability; HEK293 Cells; Humans; Models, Molecular; Polymorphism, Single Nucleotide; Protein Folding; Protein Structure, Secondary; Temperature | 2013 |
Arg399Gln polymorphism of X-ray repair cross-complementing group 1 gene is associated with angiographically documented coronary artery disease in South Indian type 2 diabetic patients.
Topics: Arginine; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Glycine; Humans; India; Polymorphism, Genetic; X-ray Repair Cross Complementing Protein 1 | 2013 |
Angiotensin-converting enzyme activity is involved in the mechanism of increased endogenous nitric oxide synthase inhibitor in patients with type 2 diabetes mellitus.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Immunoassay; Male; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Perindopril; Renin-Angiotensin System; von Willebrand Factor | 2002 |
Reduction of plasma leptin concentrations by arginine but not lipid infusion in humans.
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Glucagon; Glycerol; Heparin; Humans; Insulin; Kinetics; Leptin; Male; Middle Aged; Somatostatin | 2002 |
L-arginine-nitric oxide kinetics in normal and type 2 diabetic subjects: a stable-labelled 15N arginine approach.
Topics: Arginine; Diabetes Mellitus, Type 2; Humans; Kinetics; Male; Nitrates; Nitric Oxide; Nitrogen Isotopes | 2003 |
Plasma concentrations of asymmetric-dimethyl-arginine in type 2 diabetes associate with glycemic control and glomerular filtration rate but not with risk factors of vasculopathy.
Topics: Aged; Arginine; Blood Glucose; Blood Pressure; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glomerular Filtration Rate; Glycated Hemoglobin; Humans; Insulin; Linear Models; Male; Middle Aged; Risk Factors; Triglycerides | 2003 |
Serum extracellular superoxide dismutase in patients with type 2 diabetes: relationship to the development of micro- and macrovascular complications.
Topics: Amino Acid Substitution; Arginine; Cholesterol; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Glycated Hemoglobin; Glycine; Humans; Male; Microcirculation; Mutation, Missense; Phenotype; Predictive Value of Tests; Regression Analysis; Superoxide Dismutase | 2003 |
Anti-hypertensive agents inhibit in vivo the formation of advanced glycation end products and improve renal damage in a type 2 diabetic nephropathy rat model.
Topics: Animals; Antihypertensive Agents; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glycation End Products, Advanced; Hydralazine; Hypertension, Renal; Imidazoles; Immunohistochemistry; In Vitro Techniques; Kidney; Lipids; Lysine; Male; Olmesartan Medoxomil; Oxidation-Reduction; Proteinuria; Rats; Tetrazoles | 2003 |
Identification and functional characterization of a novel mutation of hepatocyte nuclear factor-1alpha gene in a Korean family with MODY3.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Glucose Transporter Type 2; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Korea; Leucine; Male; Models, Molecular; Monosaccharide Transport Proteins; Mutation, Missense; Nuclear Proteins; Pedigree; Promoter Regions, Genetic; Protein Conformation; Transcription Factors | 2003 |
Increased urinary levels of pentosidine, pyrraline and acrolein adduct in type 2 diabetes.
Topics: Acrolein; Adult; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Norleucine; Pyrroles; Smoking | 2003 |
L-arginine-induced vasodilation of the renal vasculature is not altered in hypertensive patients with type 2 diabetes.
Topics: Aged; Arginine; Diabetes Mellitus, Type 2; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Inulin; Kidney; Metabolic Clearance Rate; Reference Values; Regional Blood Flow; Renal Circulation; Vasodilation | 2003 |
Gln-Arg192 polymorphism of paraoxonase 1 is associated with carotid intima-media thickness in patients of type 2 diabetes mellitus of Chinese.
Topics: Amino Acid Substitution; Arginine; Aryldialkylphosphatase; Asian People; Base Sequence; Body Mass Index; Carotid Arteries; China; Diabetes Mellitus, Type 2; DNA Primers; Female; Genotype; Glutamine; Humans; Male; Middle Aged; Mutation, Missense; Polymerase Chain Reaction; Tunica Intima; Tunica Media | 2003 |
Anti-obesity effects of a mixture of thiamin, arginine, caffeine, and citric acid in non-insulin dependent diabetic KK mice.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Arginine; Caffeine; Citric Acid; Diabetes Mellitus, Type 2; Diet; Dietary Supplements; Energy Intake; Insulin; Lipids; Liver; Mice; Organ Size; Tea; Thiamine; Triglycerides | 2003 |
Effect of smoking on risk factors for cardiovascular disease in patients with diabetes mellitus and renal insufficiency.
Topics: Adult; Aged; Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Homocysteine; Humans; Kidney Transplantation; Lysine; Middle Aged; Renal Dialysis; Renal Insufficiency; Risk Factors; Smoking | 2003 |
Supplementation of L-arginine improves hypertension and lipid metabolism but not insulin resistance in diabetic rats.
Topics: Animals; Arginine; Body Weight; Diabetes Mellitus, Type 2; Dietary Supplements; Glucose Clamp Technique; Glucose Tolerance Test; Hypertension; Insulin; Male; Metabolic Syndrome; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Triglycerides | 2003 |
Rabbit aortic endothelial dysfunction by low-density lipoprotein is attenuated by L-arginine, L-ascorbate and pyridoxine.
Topics: Adult; Animals; Aorta, Thoracic; Arginine; Ascorbic Acid; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Pyridoxine; Rabbits; Vasodilation | 2003 |
Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients.
Topics: Aged; Arginine; Diabetes Mellitus, Type 2; Fasting; Female; Genotype; Glucose; Glucose Tolerance Test; Glycine; Homeostasis; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Osmolar Concentration; Polymorphism, Genetic; Receptors, Adrenergic, beta-2 | 2004 |
Alteration of beta-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Nitric Oxide Synthase; Rats; Rats, Wistar | 2004 |
The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.
Topics: Adult; Aged; Amino Acid Substitution; Arginine; Diabetes Mellitus, Type 2; Female; Genetic Markers; Genetic Variation; Humans; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Male; Middle Aged; Phosphoproteins; Sulfonylurea Compounds; Treatment Failure; White People | 2004 |
Simple non-invasive assessment of advanced glycation endproduct accumulation.
Topics: Adult; Arginine; Biopsy; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fluorescence; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Regression Analysis; Skin | 2004 |
Expression, purification, and C-terminal amidation of recombinant human glucagon-like peptide-1.
Topics: Animals; Arginine; Cathepsin A; Chromatography, Affinity; Chromatography, Ion Exchange; Cyanogen Bromide; Diabetes Mellitus, Type 2; Escherichia coli; Female; Gene Expression; Glucagon; Glucagon-Like Peptide 1; Glucose; Glutathione Transferase; Humans; Insulin; Leucine; Peptide Fragments; Protein Precursors; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins | 2004 |
Increased response of renal perfusion to the antioxidant vitamin C in type 2 diabetes.
Topics: Aged; Antioxidants; Arginine; Ascorbic Acid; Case-Control Studies; Diabetes Mellitus, Type 2; Drug Combinations; Enzyme Inhibitors; Female; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; omega-N-Methylarginine; Renal Circulation | 2004 |
Dissociation between urinary pyrraline and pentosidine concentrations in diabetic patients with advanced nephropathy.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Arginine; beta 2-Microglobulin; Biomarkers; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Humans; Lysine; Pyrroles; Reference Values; Regression Analysis | 2004 |
Inhibition of endothelial nitric oxide generation by low-density lipoprotein is partially prevented by L-arginine and L-ascorbate.
Topics: Adult; Arginine; Ascorbic Acid; Cyclic GMP; Diabetes Mellitus, Type 2; Endothelial Cells; Female; Free Radical Scavengers; Humans; Lipoproteins, LDL; Male; Middle Aged; Nitric Oxide | 2004 |
Relationship between blood levels of N-carboxymethyl-lysine and pentosidine and the severity of microangiopathy in type 2 diabetes.
Topics: Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged | 2004 |
Functional and morphological alterations of mitochondria in pancreatic beta cells from type 2 diabetic patients.
Topics: Adenine Nucleotides; Arginine; Cell Separation; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Mitochondria; Reference Values | 2005 |
Glucosepane is a major protein cross-link of the senescent human extracellular matrix. Relationship with diabetes.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arginine; Azepines; Basement Membrane; Cellular Senescence; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Extracellular Matrix; Female; Humans; Imidazoles; Kidney Failure, Chronic; Kidney Glomerulus; Lysine; Male; Middle Aged; Models, Chemical; Protein Binding; Regression Analysis; Renal Insufficiency; Skin; Time Factors | 2005 |
Serum levels of L-arginine analogues and glutathione peroxidase and catalase gene variants in Type 2 diabetes mellitus patients.
Topics: Aged; Arginine; Catalase; Diabetes Mellitus, Type 2; Female; Glutathione Peroxidase; Humans; Hungary; Male; Middle Aged; Polymorphism, Genetic | 2005 |
High serum pentosidine concentrations are associated with increased arterial stiffness and thickness in patients with type 2 diabetes.
Topics: Aged; Analysis of Variance; Arginine; Arteries; Biomechanical Phenomena; Brachial Artery; Cardiovascular Diseases; Carotid Arteries; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Linear Models; Lysine; Male; Middle Aged; Pulse; Tunica Intima; Tunica Media; Ultrasonography | 2005 |
An association between the Trp64Arg polymorphism in the beta3-adrenergic receptor gene and endometrial cancer and obesity.
Topics: Adipose Tissue; Adult; Aged; Alleles; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; DNA; DNA Restriction Enzymes; Electrophoresis, Polyacrylamide Gel; Endometrial Neoplasms; Female; Genotype; Humans; Insulin Resistance; Leukocytes; Logistic Models; Middle Aged; Obesity; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Postmenopause; Premenopause; Receptors, Adrenergic, beta-3; Tryptophan | 2004 |
Dietary L-arginine supplementation reduces fat mass in Zucker diabetic fatty rats.
Topics: Abdomen; Adipose Tissue; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Supplements; DNA Primers; Hormones; Lipids; Male; Nitrogen Oxides; Obesity; Oligonucleotide Array Sequence Analysis; Rats; Rats, Zucker; Reverse Transcriptase Polymerase Chain Reaction | 2005 |
Effect of diabetic duration on serum concentrations of endogenous inhibitor of nitric oxide synthase in patients and rats with diabetes.
Topics: Adult; Aged; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors; Vasoconstriction | 2005 |
Evaluation of advanced glycation end products and carbonyl compounds in patients with different conditions of oxidative stress.
Topics: Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dialysis Solutions; Glycated Hemoglobin; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Oxidative Stress; Peritoneal Dialysis; Pyruvaldehyde | 2005 |
Pentosidine plasma levels and relation with metabolic control in diabetic patients.
Topics: Aged; Arginine; Blood Glucose; Blood Glucose Self-Monitoring; Chromatography, Liquid; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Linear Models; Lysine; Male; Middle Aged | 2005 |
WRN gene 1367 Arg allele protects against development of type 2 diabetes mellitus.
Topics: Adenosine Triphosphatases; Adult; Aged; Amino Acid Substitution; Arginine; Cysteine; Diabetes Mellitus, Type 2; DNA Helicases; Exodeoxyribonucleases; Female; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; RecQ Helicases; Survivors; Werner Syndrome Helicase | 2005 |
Characterization of the action of S 21403 (mitiglinide) on insulin secretion and biosynthesis in normal and diabetic beta-cells.
Topics: Animals; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Gerbillinae; Glucose; Hypoglycemic Agents; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Isoindoles; Perfusion; Rats; Rats, Wistar | 2005 |
In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy.
Topics: Animals; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diet, Fat-Restricted; Disease Models, Animal; Female; Follow-Up Studies; Glycation End Products, Advanced; Immunohistochemistry; Kidney; Lysine; Male; Microscopy, Electron; Obesity; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Wistar | 2005 |
Dual mechanism of the potentiation by glucose of insulin secretion induced by arginine and tolbutamide in mouse islets.
Topics: Animals; Arginine; Calcium; Cytosol; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Tolbutamide | 2006 |
Serum asymmetric dimethylarginine as a marker of coronary microcirculation in patients with non-insulin dependent diabetes mellitus: correlation with coronary flow reserve.
Topics: Aged; Arginine; Biomarkers; Blood Flow Velocity; Coronary Artery Disease; Coronary Circulation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Male; Microcirculation; Regression Analysis | 2005 |
[Proportion of proinsulin two minutes after arginine stimulation: a pilot study].
Topics: Adult; Aged; Arginine; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Islets of Langerhans; Middle Aged; Pilot Projects; Proinsulin | 2005 |
Slowly progressing form of type 1 diabetes mellitus in children: genetic analysis compared with other forms of diabetes mellitus in Japanese children.
Topics: Age of Onset; Arginine; Asian People; Aspartic Acid; Autoantibodies; Case-Control Studies; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Progression; Female; Gene Frequency; Genotype; Haplotypes; Humans; Japan; Male; Phenotype | 2005 |
Asymmetric dimethylarginine is associated with macrovascular disease and total homocysteine in patients with type 2 diabetes.
Topics: Aged; Arginine; Arterial Occlusive Diseases; Biomarkers; Chromatography, High Pressure Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Homocysteine; Humans; Hypoglycemic Agents; Incidence; Male; Middle Aged; Nitric Oxide Synthase; Prognosis; Risk Factors; Severity of Illness Index | 2006 |
ADMA and oxidative stress may relate to the progression of renal disease: rationale and design of the VIVALDI study.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arginine; Benzimidazoles; Benzoates; Clinical Protocols; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dinoprost; Endothelium, Vascular; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Oxidative Stress; Randomized Controlled Trials as Topic; Renal Insufficiency; Telmisartan; Tetrazoles; Valine; Valsartan | 2005 |
Synergistic association of metabolic syndrome and overt nephropathy with elevated asymmetric dimethylarginine in serum and impaired cutaneous microvasodilation in patients with type 2 diabetes.
Topics: Albuminuria; Arginine; Cholesterol, HDL; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Foot; Hot Temperature; Humans; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Thrombomodulin; Vasodilation | 2006 |
Intensive treatment of risk factors in patients with type-2 diabetes mellitus is associated with improvement of endothelial function coupled with a reduction in the levels of plasma asymmetric dimethylarginine and endogenous inhibitor of nitric oxide synt
Topics: Arginine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Endothelium, Vascular; Female; Humans; Hyperglycemia; Male; Middle Aged; Nitric Oxide Synthase; Risk Factors; Tumor Necrosis Factor-alpha | 2006 |
Chronic inhibition of nitric oxide production aggravates diabetic nephropathy in Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Enzyme Inhibitors; Kidney Glomerulus; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Proteinuria; Rats; Rats, Inbred OLETF; Time Factors | 2006 |
[Blood levels of true insulin and immunoreactive insulin in evaluating beta-cell function with arginine stimulation test].
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Proinsulin | 2006 |
Common variants in HNF-1 alpha and risk of type 2 diabetes.
Topics: Adult; Amino Acid Substitution; Arginine; Blood Glucose; Body Weight; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Variation; Glucose; Hepatocyte Nuclear Factor 1-alpha; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Mutagenesis, Site-Directed; Overweight; Plasmids; Polymorphism, Single Nucleotide; Risk Factors; Transcription, Genetic | 2006 |
The Krüppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people.
Topics: Amino Acid Substitution; Apoptosis Regulatory Proteins; Arginine; Case-Control Studies; Cell Cycle Proteins; Codon; Diabetes Mellitus, Type 2; Glutamine; Humans; Parents; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Repressor Proteins; Siblings | 2006 |
Asymmetrical dimethylarginine is related to renal function, chronic inflammation and macroangiopathy in patients with Type 2 diabetes and albuminuria.
Topics: Aged; Albuminuria; Arginine; Atherosclerosis; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged | 2007 |
[Asymmetric dimethyl arginine (ADMA): a novel cardiovascular risk factor?].
Topics: Arginine; Coronary Artery Disease; Diabetes Mellitus, Type 2; Endothelium, Vascular; Homocysteine; Humans; Insulin Resistance; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Statistics as Topic | 2007 |
Diabetes mellitus exacerbates advanced glycation end product accumulation in the veins of end-stage renal failure patients.
Topics: Adult; Aged; Arginine; Brachiocephalic Veins; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Hypertension; Immunohistochemistry; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Radial Artery | 2006 |
Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes.
Topics: Aged; Arginine; C-Reactive Protein; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Middle Aged; Predictive Value of Tests; Prospective Studies; Risk Assessment | 2007 |
Pharmacokinetics and safety of arginine supplementation in animals.
Topics: Administration, Oral; Age Factors; Animal Feed; Animals; Arginine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dietary Supplements; Female; Injections, Intravenous; Male; Obesity; Pregnancy; Rats; Rats, Inbred BB; Rats, Zucker; Sheep; Sus scrofa | 2007 |
Soluble RAGE in type 2 diabetes: association with oxidative stress.
Topics: Arginine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dinoprost; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Male; Middle Aged; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2007 |
Possible role of alpha-cell insulin resistance in exaggerated glucagon responses to arginine in type 2 diabetes.
Topics: Adult; Aged; Area Under Curve; Arginine; Body Mass Index; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucagon; Humans; Insulin Resistance; Insulin-Secreting Cells; Japan; Male; Middle Aged; Reference Values | 2007 |
Angiotensin II receptor blocker inhibits abnormal accumulation of advanced glycation end products and retinal damage in a rat model of type 2 diabetes.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Arginine; Benzimidazoles; Biphenyl Compounds; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Drug Evaluation, Preclinical; Electroretinography; Gene Expression Regulation; Glycation End Products, Advanced; Lysine; Male; Rats; Rats, Sprague-Dawley; Retina; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Vascular Endothelial Growth Factor A | 2007 |
Plasma asymmetric dimethylarginine (ADMA) is associated with retinopathy in type 2 diabetes.
Topics: Aged; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Humans; Middle Aged; Multivariate Analysis; Nitric Oxide; Nitric Oxide Synthase; Regression Analysis | 2007 |
Family history of diabetes mellitus determines insulin sensitivity and beta cell function in polycystic ovary syndrome.
Topics: Adult; Anthropometry; Arginine; Blood Glucose; Blood Pressure; Body Mass Index; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucagon-Secreting Cells; Glucose Clamp Technique; Homeostasis; Hormones; Humans; Insulin Resistance; Insulin-Secreting Cells; Polycystic Ovary Syndrome | 2008 |
Soybean oil treatment impairs glucose-stimulated insulin secretion and changes fatty acid composition of normal and diabetic islets.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Acids; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Myristic Acid; Rats; Rats, Inbred Strains; Reference Values; Soybean Oil | 2007 |
Impaired vascular nitric oxide bioactivity in women with previous gestational diabetes.
Topics: Adult; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Diabetes, Gestational; Diabetic Angiopathies; Endothelium, Vascular; Female; Humans; Insulin Resistance; Male; Nitric Oxide; Obesity; Pregnancy; Reference Values; Risk Factors; Sex Factors; Vasoconstriction; Vasodilation | 2007 |
[Is the serum concentration of pentosidine a predictor of cardiovascular events in patients with type 2 diabetes and kidney disease?].
Topics: Arginine; Cardiovascular Diseases; Chromatography, High Pressure Liquid; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Lipoproteins, LDL; Lysine; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Prospective Studies; Risk Factors; Time Factors | 2007 |
Impact of family history of diabetes and ethnicity on -cell function in obese, glucose-tolerant individuals.
Topics: Adolescent; Adult; Arginine; Black or African American; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Obesity; White People | 2007 |
In vitro and pathological investigations of MODY5 with the R276X-HNF1beta (TCF2) mutation.
Topics: Adult; Age of Onset; Arginine; C-Peptide; Cells, Cultured; Codon, Nonsense; Diabetes Mellitus, Type 2; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin-Secreting Cells; Male; Pedigree; Polycystic Kidney Diseases; Transfection | 2007 |
Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes.
Topics: Aged; Amino Acid Substitution; Arginine; Cell Cycle Proteins; Diabetes Mellitus, Type 2; Female; Glutamine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Protein Serine-Threonine Kinases; Repressor Proteins; Sequence Homology, Amino Acid; White People | 2007 |
Insulin reduces plasma arginase activity in type 2 diabetic patients.
Topics: Adult; Arginase; Arginine; Blood Glucose; Carbon Radioisotopes; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Isoenzymes; Male; Middle Aged; Reference Values | 2008 |
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model.
Topics: Animals; Antimutagenic Agents; Arginine; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Cobalt; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immediate-Early Proteins; Insulin-Like Growth Factor Binding Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; NADPH Oxidases; Obesity; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta | 2008 |
Prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism and parameters of the metabolic syndrome.
Topics: Alleles; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Gene Frequency; Genotype; Histidine; Humans; Intramolecular Oxidoreductases; Lipids; Male; Metabolic Syndrome; Middle Aged; Polymorphism, Genetic; Prostaglandin-E Synthases; Waist-Hip Ratio | 2007 |
Effect of angiotensin-converting enzyme inhibitor on serum asymmetric dimethylarginine and coronary circulation in patients with type 2 diabetes mellitus.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Coronary Circulation; Diabetes Mellitus, Type 2; Female; Humans; Male; Thiazepines | 2009 |
Serum pentosidine levels are positively associated with the presence of vertebral fractures in postmenopausal women with type 2 diabetes.
Topics: Aged; Aged, 80 and over; Arginine; Bone Density; Diabetes Mellitus, Type 2; Female; Humans; Logistic Models; Lysine; Male; Middle Aged; Postmenopause; Spinal Fractures | 2008 |
Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people.
Topics: Arginine; Denmark; Diabetes Mellitus, Type 2; Female; Genetic Variation; Genotype; Humans; Male; Middle Aged; Obesity; Polymorphism, Single Nucleotide; Receptors, Adrenergic, beta-3; Tryptophan; White People | 2008 |
Effect of nebivolol and metoprolol treatments on serum asymmetric dimethlyarginine levels in hypertensive patients with type 2 diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Arginine; Benzopyrans; Confounding Factors, Epidemiologic; Diabetes Mellitus, Type 2; Ethanolamines; Humans; Hypertension; Metoprolol; Nebivolol | 2008 |
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes.
Topics: Amiloride; Amino Acids, Cyclic; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Synergism; Homeostasis; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulin-Secreting Cells; Keto Acids; Ketoglutarate Dehydrogenase Complex; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Sodium-Calcium Exchanger | 2008 |
Hyperfunction of the entero-PP axis in non-insulin dependent diabetes mellitus.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Digestive System; Eating; Female; Humans; Insulin; Male; Meat; Middle Aged; Pancreatic Polypeptide; Radioimmunoassay | 1983 |
Time-dependent inhibition of insulin release: suppression of the arginine effect by hyperglycaemia.
Topics: Adult; Arginine; Depression, Chemical; Diabetes Mellitus, Type 2; Drug Synergism; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Obesity; Radioimmunoassay; Time Factors | 1984 |
Effect of middle-term gliclazide treatment on insulin secretion in non-insulin dependent diabetics.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Gliclazide; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Iodine Radioisotopes; Male; Middle Aged; Sulfonylurea Compounds; Time Factors | 1984 |
Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.
Topics: Adult; Aging; Arginine; Blood Glucose; Catecholamines; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Obesity | 1984 |
Glucagon secretion in rats with non-insulin-dependent diabetes: an in vivo and in vitro study.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucagon; In Vitro Techniques; Male; Pancreas; Rats; Rats, Inbred Strains | 1984 |
A mutation in the beta 3-adrenergic receptor gene is associated with obesity and hyperinsulinemia in Japanese subjects.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Sequence; Arginine; Base Sequence; Blood Pressure; Deoxyribonucleases, Type II Site-Specific; Diabetes Mellitus, Type 2; DNA Primers; Female; Gene Frequency; Genetic Carrier Screening; Homozygote; Humans; Hyperinsulinism; Insulin; Male; Middle Aged; Molecular Sequence Data; Obesity; Point Mutation; Polymerase Chain Reaction; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reference Values; Tryptophan | 1995 |
The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Humans; Hypertrophy; Inflammation; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Mice, Mutant Strains; Obesity; Sex Characteristics; Time Factors | 1995 |
Gln-Arg192 polymorphism of paraoxonase and coronary heart disease in type 2 diabetes.
Topics: Arginine; Aryldialkylphosphatase; Case-Control Studies; Coronary Disease; Diabetes Mellitus, Type 2; Esterases; Female; Genotype; Glutamine; Humans; Male; Middle Aged; Polymorphism, Genetic; Regression Analysis; Risk Factors | 1995 |
Endothelial-dependent vasodilation is preserved in non-insulin-dependent Zucker fatty diabetic rats.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Arginine; Arterioles; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Intestines; Least-Squares Analysis; Male; Nitric Oxide; Nitroprusside; Obesity; omega-N-Methylarginine; Rats; Rats, Zucker; Thinness; Vasodilation | 1995 |
Paradoxical inhibition of insulin secretion by glucose in non-insulin-dependent diabetic patients.
Topics: Arginine; Blood Glucose; Blood Proteins; Body Mass Index; C-Peptide; Cohort Studies; Diabetes Mellitus, Type 2; Follow-Up Studies; Glucose; Glucose Clamp Technique; Hematocrit; Humans; Insulin; Insulin Secretion; Kinetics; Male; Middle Aged; Reference Values; Time Factors | 1995 |
Blunted GH response to growth hormone-releasing hormone (GHRH) alone or combined with arginine in non-insulin-dependent diabetes mellitus.
Topics: Adult; Arginine; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Male; Middle Aged | 1995 |
Clinical characteristics of subjects with a missense mutation in glucokinase.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Arginine; Blood Glucose; Blood Pressure; C-Peptide; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucokinase; Glycated Hemoglobin; Glycine; Humans; Insulin; Male; Middle Aged; Pedigree; Point Mutation; Regression Analysis; Triglycerides | 1995 |
Age-related changes in vascular reactivity in genetically diabetic rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Calcimycin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker | 1995 |
Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease.
Topics: Adult; Aged; Alanine; Arginine; Base Sequence; Case-Control Studies; Codon; Deoxyribonucleases, Type II Site-Specific; Diabetes Mellitus, Type 2; DNA Primers; Female; Finland; Genotype; Glycine; Humans; India; Insulin Receptor Substrate Proteins; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphoproteins; Point Mutation; Polymerase Chain Reaction; Proline; Reference Values; Restriction Mapping; Risk Factors | 1995 |
The role of islet secretory function in the development of diabetes in the GK Wistar rat.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Glyceraldehyde; Glycerol; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Potassium Chloride; Rats; Rats, Wistar; Reference Values | 1994 |
Glucosamine inhibits glucokinase in vitro and produces a glucose-specific impairment of in vivo insulin secretion in rats.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Glucokinase; Glucosamine; Glucose; Humans; In Vitro Techniques; Infusions, Intravenous; Islets of Langerhans; Kinetics; Male; Rats; Rats, Sprague-Dawley | 1994 |
Molecular scanning of the glycogen synthase and insulin receptor substrate-1 genes in Japanese subjects with non-insulin-dependent diabetes mellitus.
Topics: Alanine; Alleles; Amino Acid Sequence; Arginine; Base Sequence; Blood Glucose; Diabetes Mellitus, Type 2; DNA Primers; Genotype; Glycated Hemoglobin; Glycine; Glycogen Synthase; Humans; Insulin; Insulin Receptor Substrate Proteins; Japan; Middle Aged; Molecular Sequence Data; Phosphoproteins; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Proline; Repetitive Sequences, Nucleic Acid | 1994 |
Functional properties of a heterozygous mutation (Arg1174-->Gln) in the tyrosine kinase domain of the insulin receptor from a type A insulin resistant patient.
Topics: Adult; Amino Acid Sequence; Arginine; Base Sequence; Cell Line, Transformed; Cell Transformation, Viral; Diabetes Mellitus, Type 2; Down-Regulation; Female; Glutamine; Heterozygote; Humans; Insulin; Lymphocytes; Molecular Sequence Data; Mutation; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Spain | 1994 |
Plasma glucagon responses to insulin-induced hypoglycemia and arginine in spontaneous non-insulin-dependent diabetes mellitus (NIDDM) rats, Otsuka Long Evans Tokushima Fatty (OLETF) strain.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Glucagon; Hypoglycemia; Immunohistochemistry; Infusions, Intravenous; Insulin; Male; Pancreas; Pancreatic Hormones; Physical Conditioning, Animal; Radioimmunoassay; Rats; Rats, Inbred Strains; Rats, Mutant Strains | 1993 |
Pentosidine content in skin collagen from type II diabetic patients.
Topics: Adult; Analysis of Variance; Arginine; Biomarkers; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dipeptides; Humans; Lysine; Middle Aged; Reference Values; Skin | 1994 |
Selective impairment of the cytoplasmic Ca2+ response to glucose in pancreatic beta cells of streptozocin-induced non-insulin-dependent diabetic rats.
Topics: Animals; Animals, Newborn; Arginine; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Wistar; Streptozocin; Time Factors | 1993 |
Differential effects of type 2 (non-insulin-dependent) diabetes mellitus on pentosidine formation in skin and glomerular basement membrane.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Basement Membrane; Biomarkers; Child; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Female; Humans; Infant; Kidney Glomerulus; Lysine; Male; Middle Aged; Skin; Skin Aging | 1993 |
Impact of diabetic inheritance on glucose tolerance and insulin secretion in spontaneously diabetic GK-Wistar rats.
Topics: Animals; Arginine; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Hybridization, Genetic; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Rats, Wistar; Sex Factors; Species Specificity | 1994 |
The Maillard protein cross-link pentosidine in urine from diabetic patients.
Topics: Aged; Arginine; Chromatography, Gel; Chromatography, High Pressure Liquid; Creatinine; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Female; Humans; Hydroxyproline; Lysine; Maillard Reaction; Male; Middle Aged; Reference Values | 1993 |
GLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats.
Topics: 3-O-Methylglucose; Animals; Arginine; Biological Transport; Blood Glucose; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Transporter Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Methylglucosides; Mifepristone; Monosaccharide Transport Proteins; Rats; Rats, Zucker | 1993 |
No effect of deferoxamine therapy on glucose homeostasis and insulin secretion in individuals with NIDDM and elevated serum ferritin.
Topics: Arginine; Blood Glucose; C-Peptide; Deferoxamine; Diabetes Mellitus, Type 2; Ferritins; Follow-Up Studies; Humans; Insulin; Insulin Secretion; Kinetics; Middle Aged; Reference Values; Time Factors | 1993 |
GLUT2 expression and function in beta-cells of GK rats with NIDDM. Dissociation between reductions in glucose transport and glucose-stimulated insulin secretion.
Topics: Aging; Animals; Arginine; Biological Transport; Cell Membrane; Diabetes Mellitus, Type 2; Gene Expression; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; RNA, Messenger; Species Specificity | 1993 |
Maillard reaction products and their relation to complications in insulin-dependent diabetes mellitus.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Retinopathy; Female; Humans; Lysine; Maillard Reaction; Male; Microcirculation; Middle Aged; Skin | 1993 |
Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation.
Topics: Adenine; Adolescent; Adult; Aged; Arginine; Blood Glucose; Body Mass Index; C-Peptide; Child; Child, Preschool; Deafness; Diabetes Mellitus, Type 2; Female; Genomic Imprinting; Glucose Tolerance Test; Glycated Hemoglobin; Guanine; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Pedigree; Periodicity; Phenotype; Point Mutation; Reference Values; RNA, Transfer, Leu; Sex Characteristics | 1996 |
Microalbuminuria in NIDDM is caused by increased excretion of unmodified albumin.
Topics: Adult; Albuminuria; Arginine; Blood Pressure; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Kidney; Male; Middle Aged; Reference Values; Serum Albumin | 1996 |
A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies.
Topics: Arginine; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Diabetes Mellitus, Type 2; DNA; Enzyme Activation; Gene Expression; Glycine; Hematopoietic Stem Cells; Humans; Insulin; Insulin Receptor Substrate Proteins; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Polymerase Chain Reaction; Polymorphism, Genetic; Receptor, Insulin; Recombinant Proteins; Signal Transduction; Thymidine; Transfection | 1996 |
Impaired coupling of glucose signal to the exocytotic machinery in diabetic GK rats: a defect ameliorated by cAMP.
Topics: Animals; Arginine; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Diabetes Mellitus, Type 2; Diazoxide; Exocytosis; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Rats; Rats, Mutant Strains; Reference Values | 1996 |
Endothelial function and adrenergic reactivity in human type-II diabetic resistance arteries.
Topics: Acetylcholine; Aged; Arginine; Arteries; Case-Control Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Norepinephrine; Receptors, Adrenergic, alpha; Skin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1996 |
Association of Trp64Arg mutation of the beta3-adrenergic-receptor with NIDDM and body weight gain.
Topics: Age of Onset; Alleles; Arginine; Confidence Intervals; Diabetes Mellitus, Type 2; Finland; France; Genotype; Humans; Indians, North American; Obesity; Point Mutation; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reference Values; Tryptophan; United States; Weight Gain | 1996 |
No association between the Gly971Arg variant of the insulin receptor substrate 1 gene and NIDDM in the Taiwanese population.
Topics: Adult; Amino Acid Sequence; Arginine; Base Sequence; Child; Diabetes Mellitus, Type 2; DNA Primers; Female; Genetic Variation; Glucose Intolerance; Glycine; Humans; Insulin Receptor Substrate Proteins; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphoproteins; Polymerase Chain Reaction; Reference Values; Taiwan | 1996 |
Effect of sulfonylurea withdrawal on proinsulin levels, B cell function, and glucose disposal in subjects with noninsulin-dependent diabetes mellitus.
Topics: Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Proinsulin; Sulfonylurea Compounds | 1996 |
Trp64Arg mutation in beta 3-adrenoceptor gene of doubtful significance for obesity and insulin resistance.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Heterozygote; Humans; Insulin Resistance; Mutation; Obesity; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tryptophan | 1996 |
Accumulation of albumin-linked and free-form pentosidine in the circulation of uremic patients with end-stage renal failure: renal implications in the pathophysiology of pentosidine.
Topics: Animals; Arginine; beta 2-Microglobulin; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diet; Glomerulonephritis; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Nephrectomy; Oxidation-Reduction; Protein Binding; Rats; Rats, Wistar; Serum Albumin; Uremia | 1996 |
Impaired insulin secretion and excessive hepatic glucose production are both early events in the diabetic GK rat.
Topics: Age Factors; Animals; Arginine; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Glucose; Insulin; Insulin Resistance; Insulin Secretion; Liver; Muscle, Skeletal; Rats; Rats, Mutant Strains; Rats, Wistar | 1996 |
Pancreatic A-cell function in the partially pancreatectomized Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucagon; Insulin; Islets of Langerhans; Male; Niacinamide; Organ Size; Pancreatectomy; Rats | 1996 |
Beta 3-adrenoceptor gene variant in obesity and insulin resistance.
Topics: Arginine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Obesity; Point Mutation; Receptors, Adrenergic, beta; Tryptophan | 1996 |
Beta 3-adrenoceptor gene variant in obesity and insulin resistance.
Topics: Arginine; Diabetes Mellitus, Type 2; Disease Susceptibility; Humans; Insulin Resistance; Obesity; Point Mutation; Receptors, Adrenergic, beta; Tryptophan | 1996 |
Paraoxonase polymorphism Met-Leu54 is associated with modified serum concentrations of the enzyme. A possible link between the paraoxonase gene and increased risk of cardiovascular disease in diabetes.
Topics: Aged; Alleles; Arginine; Aryldialkylphosphatase; Cardiovascular Diseases; Cholesterol; Diabetes Mellitus, Type 2; DNA; Esterases; Female; Gene Expression Regulation; Genetic Linkage; Humans; Leucine; Lipoproteins, HDL; Male; Middle Aged; Odds Ratio; Point Mutation; Polymorphism, Genetic; Risk Factors | 1997 |
Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population.
Topics: Adult; Age of Onset; Aged; Arginine; Case-Control Studies; Cysteine; Diabetes Mellitus, Type 2; Female; Genetic Variation; Homozygote; Humans; Japan; Male; Middle Aged; Mutation; Myocardial Infarction; Polymorphism, Genetic; Werner Syndrome | 1997 |
Prevalence of the Trp64Arg missense mutation of the beta3-adrenergic receptor gene in Japanese subjects.
Topics: Adult; Aged; Alleles; Arginine; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Japan; Male; Middle Aged; Obesity; Point Mutation; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tryptophan | 1997 |
Arginine reduces kidney collagen accumulation, cross-linking, lipid peroxidation, glycoxidation, kidney weight and albuminuria in the diabetic kk mouse.
Topics: Albuminuria; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Glucose; Glycosylation; Hydroxyl Radical; Kidney; Lipid Peroxidation; Mice; Mice, Inbred Strains; Nitric Oxide; Organ Size; Oxidation-Reduction | 1997 |
A mutation of the beta 3-adrenergic receptor is associated with visceral obesity but decreased serum triglyceride.
Topics: Adult; Aged; Alleles; Arginine; Body Mass Index; Cholesterol; Deoxyribonucleases, Type II Site-Specific; Diabetes Mellitus, Type 2; Genotype; Glucose Intolerance; Heterozygote; Homozygote; Humans; Insulin; Male; Middle Aged; Obesity; Phenotype; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reference Values; Triglycerides; Tryptophan | 1997 |
The beta3-adrenergic receptor in the obesity and diabetes prone rhesus monkey is very similar to human and contains arginine at codon 64.
Topics: Amino Acid Sequence; Animals; Arginine; Base Sequence; Codon; Cytosine; Diabetes Mellitus, Type 2; DNA; Exons; Humans; Macaca mulatta; Male; Molecular Sequence Data; Obesity; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3 | 1997 |
The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of association with NIDDM and features of insulin resistance syndrome.
Topics: Adult; Alleles; Arginine; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Finland; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin Resistance; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Syndrome; Tryptophan | 1997 |
Trp64Arg mutation of beta 3-adrenergic receptor and insulin sensitivity in subjects with glucose intolerance.
Topics: Adipose Tissue; Adult; Aged; Alleles; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Middle Aged; Point Mutation; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tryptophan | 1997 |
L-arginine for testing endothelium-dependent vascular functions in health and disease.
Topics: Adenosine Diphosphate; Adult; Age Factors; Arginine; Blood Glucose; Blood Pressure; Blood Viscosity; Cholesterol; Diabetes Mellitus, Type 2; Diastole; Female; Humans; Hypercholesterolemia; Hypertension; Infusions, Intravenous; Male; Middle Aged; omega-N-Methylarginine; Platelet Aggregation; Reference Values; Regression Analysis; Smoking; Stereoisomerism; Systole | 1997 |
Release of incompletely processed proinsulin is the cause of the disproportionate proinsulinemia of NIDDM.
Topics: Adult; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Male; Middle Aged; Proinsulin; Protein Precursors; Protein Processing, Post-Translational; Radioimmunoassay; Reference Values; Regression Analysis | 1997 |
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
Topics: Adolescent; Adult; Aged; Animals; Antibodies; Arginine; Collagen; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Kidney Glomerulus; Lipid Peroxidation; Lysine; Male; Malondialdehyde; Mice; Middle Aged; Nephrotic Syndrome; Norleucine; Pyrroles; Rabbits | 1997 |
The beta(3)-adrenergic receptor TRP64ARG polymorphism and obesity in Alaskan Eskimos.
Topics: Adult; Alaska; Alleles; Arginine; Asian People; Blood Pressure; Body Mass Index; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Humans; Inuit; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Genetic; Receptors, Adrenergic, beta; Tryptophan | 1997 |
Advanced glycation end products in human penis: elevation in diabetic tissue, site of deposition, and possible effect through iNOS or eNOS.
Topics: Adult; Aged; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Electron Probe Microanalysis; Endothelium; Enzyme Induction; Erectile Dysfunction; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lysine; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Norleucine; Penis; Pyrroles | 1997 |
TRP64ARG beta 3-adrenergic receptor and obesity in Mexican Americans.
Topics: Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Mexican Americans; Middle Aged; Mutation; Obesity; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Syndrome; Texas; Tryptophan | 1997 |
Disproportionately elevated proinsulin levels reflect the degree of impaired B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Islets of Langerhans; Male; Middle Aged; Proinsulin | 1998 |
Coronary artery responses to physiological stimuli are improved by deferoxamine but not by L-arginine in non-insulin-dependent diabetic patients with angiographically normal coronary arteries and no other risk factors.
Topics: Adult; Antidotes; Arginine; Cold Temperature; Coronary Angiography; Coronary Vessels; Deferoxamine; Diabetes Mellitus, Type 2; Female; Hemodynamics; Humans; Iron Chelating Agents; Male; Middle Aged; Papaverine; Risk Factors; Stress, Physiological; Vasodilator Agents; Vasomotor System | 1998 |
Increased pentosidine, an advanced glycation end product, in plasma and synovial fluid from patients with rheumatoid arthritis and its relation with inflammatory markers.
Topics: Acute-Phase Proteins; Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Diabetes Mellitus, Type 2; Extracellular Matrix; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Osteoarthritis; Synovial Fluid | 1998 |
Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Niacinamide; Rats; Rats, Wistar; Streptozocin; Tolbutamide | 1998 |
Transplantation of syngenic pancreatic islets into rats with streptozotocin induced non insulin dependent diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Rats; Rats, Inbred Lew; Transplantation, Isogeneic | 1997 |
The significance of the Trp 64 Arg mutation of the beta3-adrenergic receptor gene in impaired glucose tolerance, non-insulin-dependent diabetes mellitus, and insulin resistance in Japanese subjects.
Topics: Adult; Amino Acid Substitution; Arginine; Blood Pressure; Body Mass Index; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genotype; Glucose Intolerance; Humans; Insulin Resistance; Japan; Lipids; Male; Middle Aged; Point Mutation; Receptors, Adrenergic, beta; Tryptophan | 1998 |
NEFA elevation during a hyperglycaemic clamp enhances insulin secretion.
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus, Type 2; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glucose Tolerance Test; Heparin; Humans; Hyperglycemia; Insulin; Insulin Secretion; Male; Middle Aged; Triglycerides | 1998 |
Glucosamine infusion in rats mimics the beta-cell dysfunction of non-insulin-dependent diabetes mellitus.
Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucosamine; Glucose; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Calcium; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Gene Expression Regulation; Glucose; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Heterozygote; Homozygote; Immunohistochemistry; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Knockout; Nuclear Proteins; Organ Size; Pancreas; RNA, Messenger; Transcription Factors | 1998 |
Trp64Arg mutation of beta3-adrenergic receptor and non-insulin dependent diabetes mellitus.
Topics: Adipose Tissue; Alleles; Animals; Arginine; Body Mass Index; Diabetes Mellitus, Type 2; Gene Frequency; Genotype; Humans; Hypoglycemic Agents; Insulin; Insulin Resistance; Middle Aged; Point Mutation; Rats; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; RNA, Messenger; Tryptophan | 1998 |
Clinical features associated with the homozygous Trp64Arg mutation of the beta3-adrenergic receptor: no evidence for its association with obesity in Japanese.
Topics: Arginine; Blood Pressure; Body Mass Index; Cholesterol, LDL; Cohort Studies; Diabetes Mellitus, Type 2; Electrocardiography; Female; Gene Frequency; Genotype; Humans; Japan; Male; Middle Aged; Obesity; Point Mutation; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Triglycerides; Tryptophan | 1998 |
Association of the Trp64Arg mutation of the beta3-adrenergic receptor with fatty liver and mild glucose intolerance in Japanese subjects.
Topics: Alleles; Arginine; Diabetes Mellitus, Type 2; Fatty Liver; Gene Frequency; Genotype; Glucose Intolerance; Heterozygote; Homozygote; Humans; Mutation; Obesity; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tryptophan | 1998 |
The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.
Topics: Adult; Aging; Alleles; Arginine; Body Mass Index; Body Temperature Regulation; Body Weight; Cholesterol; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Genotype; Humans; Lipolysis; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Random Allocation; Receptors, Adrenergic, beta; Tryptophan | 1998 |
Glycoxidation, and protein and DNA oxidation in patients with diabetes mellitus.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyguanosine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Lysine; Middle Aged; Oxidative Stress; Statistics, Nonparametric; Tyrosine | 1998 |
Beta3-adrenergic receptor gene polymorphism is not associated with hypertension in NIDDM patients without nephropathy.
Topics: Adult; Aged; Arginine; Codon; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Mutation; Receptors, Adrenergic, beta; Tryptophan | 1998 |
Trp64Arg mutation of beta3-adrenoceptor gene is associated with diabetic nephropathy in Type II diabetes mellitus.
Topics: Aged; Arginine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Male; Middle Aged; Mutation; Receptors, Adrenergic, beta; Tryptophan | 1998 |
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia | 1999 |
Paraoxonase 192 Gln/Arg gene polymorphism, coronary artery disease, and myocardial infarction in type 2 diabetes.
Topics: Arginine; Aryldialkylphosphatase; Coronary Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathies; DNA; Esterases; Female; Gene Frequency; Genotype; Glutamine; Humans; Leukocytes; Male; Middle Aged; Myocardial Infarction; Polymerase Chain Reaction; Polymorphism, Genetic | 1999 |
Increased serum levels of pentosidine, but not carboxymethyl lysine, in type 2 diabetes without obvious diabetic nephropathy.
Topics: Albuminuria; Arginine; Biomarkers; Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Reference Values | 1999 |
Evidence for iNOS-dependent peroxynitrite production in diabetic platelets.
Topics: Adult; Arginine; Blood Platelets; Blotting, Western; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fluorescent Dyes; Humans; Male; Microscopy, Confocal; Middle Aged; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Spectrometry, Fluorescence | 1999 |
Three new mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization.
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA; DNA-Binding Proteins; Female; Glucagon; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Mutation; Nuclear Proteins; Promoter Regions, Genetic; Transcription Factors | 1999 |
Is Trp64Arg polymorphism of beta3-adrenergic receptor a clinically useful marker for the predisposition to diabetic nephropathy in Type II diabetic patients?
Topics: Arginine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Genetic Markers; Humans; Receptors, Adrenergic, beta; Tryptophan | 1999 |
Polymorphism of the beta3-adrenergic receptor gene and weight gain in pregnant diabetic women.
Topics: Adult; Amino Acid Substitution; Arginine; Body Mass Index; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Genotype; Heterozygote; Homozygote; Humans; Obesity; Polymorphism, Genetic; Pregnancy; Pregnancy in Diabetics; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tryptophan; Weight Gain | 1999 |
Relationship between the histopathology of the endocrine-exocrine pancreas parenchyma and beta-cell function in the Chinese hamster CHIG/Han subline.
Topics: Animals; Arginine; Blood Glucose; Cell Count; Cell Separation; Cells, Cultured; Cricetinae; Cricetulus; Culture Media, Conditioned; Diabetes Mellitus, Type 2; Disease Models, Animal; Female; Fluorescent Antibody Technique, Indirect; Glucose; Immunoenzyme Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male | 1999 |
Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes.
Topics: Adult; Amino Acid Substitution; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Family; Female; Genotype; Germany; Glucose Clamp Technique; Glucose Tolerance Test; Glycine; Humans; Infusions, Intravenous; Insulin; Insulin Receptor Substrate Proteins; Male; Metabolic Clearance Rate; Phosphoproteins; Polymorphism, Genetic; White People | 1999 |
Insulin secretion and insulin sensitivity in diabetic and non-diabetic subjects with hepatic nuclear factor-1alpha (maturity-onset diabetes of the young-3) mutations.
Topics: Adolescent; Adult; Arginine; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Glucokinase; Glucose Clamp Technique; Glucose Tolerance Test; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Middle Aged; Mutation; Nuclear Proteins; Transcription Factors | 1999 |
Circulating adhesion molecules in humans: role of hyperglycemia and hyperinsulinemia.
Topics: Adult; Arginine; Circadian Rhythm; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Humans; Hyperglycemia; Hyperinsulinism; Intercellular Adhesion Molecule-1; Male; Middle Aged; Reference Values; Solubility; Vascular Cell Adhesion Molecule-1 | 2000 |
A syndrome of molybdenosis, copper deficiency, and type 2 diabetes in the moose population of south-west Sweden.
Topics: Animals; Arginine; Case-Control Studies; Copper; Deer; Deficiency Diseases; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Kidney; Liver; Lysine; Molybdenum; Sweden | 2000 |
Hemodynamic effects of acute hyperglycemia in type 2 diabetic patients.
Topics: Adult; Arginine; Blood Pressure; Blood Volume; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucose Clamp Technique; Glutathione; Heart Rate; Hemodynamics; Humans; Hyperglycemia; Insulin; Male; Middle Aged; Norepinephrine; Octreotide | 2000 |
Trp64Arg polymorphism of the beta3-adrenergic receptor is not associated with diabetic nephropathy in Japanese patients with type 2 diabetes.
Topics: Albuminuria; Amino Acid Substitution; Arginine; Asian People; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Female; Genotype; Humans; Japan; Male; Middle Aged; Polymorphism, Genetic; Proteinuria; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tryptophan | 2000 |
Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene.
Topics: Adult; Amyloid; Arginine; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Glucagon; Hepatocyte Nuclear Factor 4; Humans; Hypoglycemia; Insulin; Islet Amyloid Polypeptide; Male; Mutation; Pancreatic Polypeptide; Phosphoproteins; Transcription Factors | 2000 |
Insulin response to glucose is lower in individuals homozygous for the Arg 64 variant of the beta-3-adrenergic receptor.
Topics: Adult; Age of Onset; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Fasting; Female; Genetic Variation; Genotype; Glucose Tolerance Test; Heterozygote; Humans; Insulin; Insulin Secretion; Leptin; Male; Phenotype; Receptors, Adrenergic, beta-3; Reference Values | 2000 |
Nitric oxide synthase activity in retinas from non-insulin-dependent diabetic Goto-Kakizaki rats: correlation with blood-retinal barrier permeability.
Topics: Animals; Arginine; Blood Glucose; Blood-Retinal Barrier; Blotting, Western; Densitometry; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Fluorescein Angiography; Guanidines; Immunohistochemistry; Interleukin-1; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats; Rats, Inbred Strains; Rats, Wistar; Retina; Retinal Vessels | 2000 |
Nitrite, endothelin and E-selectin plasma levels after arginine infusion in normal, obese and type 2 diabetic subjects.
Topics: Analysis of Variance; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; E-Selectin; Endothelins; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Nitrates; Obesity | 2000 |
Beta 3-adrenergic receptor gene polymorphism and type 2 diabetes in a Caucasian population.
Topics: Adult; Aged; Alleles; Arginine; Deoxyribonucleases, Type II Site-Specific; Diabetes Mellitus, Type 2; DNA; Female; Gene Frequency; Heterozygote; Homozygote; Humans; Leukocytes; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta-3; Tryptophan; Weight Gain; White People | 2001 |
Beta(2)-adrenergic receptor gene variation and hypertension in subjects with type 2 diabetes.
Topics: Aged; Analysis of Variance; Arginine; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Variation; Genotype; Glutamic Acid; Glutamine; Glycine; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Receptors, Adrenergic, beta-2 | 2001 |
Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)--adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes.
Topics: Alleles; Amino Acid Substitution; Arginine; Blood Glucose; Blood Pressure; Cholesterol, HDL; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Genetic Variation; Genotype; Glutamic Acid; Glutamine; Homozygote; Humans; Insulin; Male; Middle Aged; Nuclear Family; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; Reference Values; Sweden; Triglycerides; Tryptophan; White People | 2001 |
Paraoxonase 1 192 Gln/Arg gene polymorphism and cerebrovascular disease: interaction with type 2 diabetes.
Topics: Aged; Alleles; Arginine; Aryldialkylphosphatase; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Esterases; Female; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Smoking | 2001 |
A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation.
Topics: Amino Acid Sequence; Arginine; Axin Protein; beta Catenin; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cytoskeletal Proteins; Diabetes Mellitus, Type 2; Glycogen Synthase Kinase 3; Humans; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphates; Phosphorylation; Protein Structure, Tertiary; Proteins; Repressor Proteins; Serine; Substrate Specificity; Trans-Activators | 2001 |
Impaired L-arginine uptake in platelets from type-2 diabetic patients.
Topics: Aged; Arginine; Blood Platelets; Calcimycin; Calcium; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Down-Regulation; Female; Humans; Kinetics; Male; Middle Aged; Nitric Oxide; Time Factors | 2001 |
Genotype Arg/Arg, but not Trp/Arg, of the Trp64Arg polymorphism of the beta(3)-adrenergic receptor is associated with type 2 diabetes and obesity in a large Japanese sample.
Topics: Aged; Amino Acid Substitution; Arginine; Asian People; Blood Pressure; Body Mass Index; Cholesterol; Cohort Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Genotype; Glucose Intolerance; Humans; Japan; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta-3; Risk Factors; Tryptophan | 2001 |
Enhanced colonic peristalsis by impairment of nitrergic enteric neurons in spontaneously diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Colon; Diabetes Mellitus, Type 2; Enteric Nervous System; Enzyme Inhibitors; In Vitro Techniques; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Peristalsis; Rats; Rats, Inbred OLETF; Reflex | 2001 |
Erectile and endothelial dysfunction in Type II diabetes: a possible link.
Topics: Arginine; Blood Coagulation; Blood Pressure; Cell Adhesion Molecules; Diabetes Mellitus, Type 2; Endothelium, Vascular; Erectile Dysfunction; Fibrinolysis; Glycated Hemoglobin; Humans; Intercellular Adhesion Molecule-1; Male; Middle Aged; P-Selectin; Platelet Aggregation; Thrombomodulin | 2001 |
Insulin secretion to glucose as well as nonglucose stimuli is impaired in spontaneously diabetic Nagoya-Shibata-Yasuda mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Blood Glucose; Calcium Channel Agonists; Cell Separation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Stimulation, Chemical | 2001 |
Plasma concentrations of asymmetric dimethylarginine are increased in patients with type 2 diabetes mellitus.
Topics: Arginine; Blood Glucose; Case-Control Studies; Cholesterol; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase | 2001 |
[Investigation and comparison of the beta3-adrenergic receptor gene Trp64Arg mutation in the Chinese and Japanese].
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Arginine; Asian People; Blood Pressure; Body Mass Index; China; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gene Frequency; Heart Rate; Humans; Hyperlipidemias; Japan; Male; Middle Aged; Mutation; Receptors, Adrenergic, beta-3; Triglycerides; Tryptophan | 2000 |
Normalization of cytoplasmic calcium response in pancreatic beta-cells of spontaneously diabetic GK rat by the treatment with T-1095, a specific inhibitor of renal Na+-glucose co-transporters.
Topics: Animals; Arginine; Blood Glucose; Calcium; Carbonates; Diabetes Mellitus, Type 2; Glucosides; Glycated Hemoglobin; Hyperglycemia; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Male; Monosaccharide Transport Proteins; Rats; Rats, Wistar | 2002 |
Transient neonatal diabetes mellitus, type 4, type 1 diabetes mellitus, or MODY: which disease is it, anyway?
Topics: Adult; Arginine; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucose Tolerance Test; Humans; Infant; Insulin; Insulin Secretion; Islets of Langerhans; Male; Tolbutamide | 2002 |
Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Eating; Enzyme Inhibitors; Hypertriglyceridemia; Insulin; Lipid Metabolism; Lipids; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Obesity; Postprandial Period; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Species Specificity; Time | 2002 |
Arginine induced insulin release in patients with newly onset non-insulin-dependent diabetes mellitus.
Topics: Adult; Aged; Arginine; C-Peptide; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin Secretion; Male; Middle Aged | 1992 |
Short- and long-term gliclazide effects on pancreatic islet cell function and hepatic insulin extraction in non-insulin-dependent diabetes mellitus.
Topics: Administration, Oral; Adult; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Gliclazide; Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Islets of Langerhans; Liver; Male; Middle Aged; Sulfonylurea Compounds; Time Factors | 1992 |
Impaired endothelium-dependent and independent vasodilation in patients with type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Acetylcholine; Analysis of Variance; Arginine; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Forearm; Humans; Ischemia; Male; Middle Aged; Muscles; Nitroglycerin; omega-N-Methylarginine; Reference Values; Regional Blood Flow; Vasodilation | 1992 |
Responsiveness and memory of the pancreatic B-cells to the insulin secretagogues D-glucose and L-arginine in prediabetic and diabetic rabbits.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Ligation; Male; Pancreatic Ducts; Perfusion; Rabbits | 1992 |
Effect of nifedipine on glucose potentiation of the acute insulin response to arginine in non-insulin-dependent diabetics.
Topics: Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Drug Synergism; Female; Glucose; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Nifedipine | 1991 |
Abnormal glucagon response to arginine and its normalization in obese hyperinsulinaemic patients with glucose intolerance: importance of insulin action on pancreatic alpha cells.
Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Obesity; Reference Values | 1991 |
Effect of epinephrine on pancreatic beta-cell and alpha-cell function in patients with NIDDM.
Topics: Analysis of Variance; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Epinephrine; Glucagon; Humans; Infusions, Intravenous; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Middle Aged; Reference Values | 1991 |
Beta-cell dysfunction in hyperglycaemic rat models: recovery of glucose-induced insulin secretion with lowering of the ambient glucose level.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Organ Size; Pancreatectomy; Perfusion; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Abnormal regulation by glucose of somatostatin secretion in the perfused pancreas of NIDDM rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin | 1990 |
Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine.
Topics: Administration, Oral; Adult; Aged; Arginine; Chromatography, Gel; Diabetes Mellitus, Type 2; Fasting; Female; Glucagon; Glucagon-Like Peptide 1; Glucose; Humans; Infusions, Intravenous; Male; Middle Aged; Peptide Fragments; Proglucagon; Protein Precursors; Radioimmunoassay | 1991 |
Abnormal B-cell function in rats with non-insulin-dependent diabetes induced by neonatal streptozotocin: effect of in vivo insulin, phlorizin, or vanadate treatments.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Phlorhizin; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; In Vitro Techniques; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Reference Values | 1991 |
Islet function and insulin sensitivity in the non-diabetic offspring of conjugal type 2 diabetic patients.
Topics: Adult; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Reference Values | 1990 |
[Plasma pancreatic glucagon assay and the clinical significance].
Topics: Arginine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Glucagonoma; Glucose Tolerance Test; Humans; Insulin; Pancreatic Neoplasms; Radioimmunoassay; Specimen Handling | 1990 |
Long-term gliclazide treatment improves the in vitro glucose-induced insulin release in rats with type 2 (non-insulin-dependent) diabetes induced by neonatal streptozotocin.
Topics: Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gliclazide; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Rats, Inbred Strains; Reference Values; Streptozocin; Sulfonylurea Compounds | 1989 |
Evaluation and clinical applications of measurement of urinary growth hormone in diabetic subjects.
Topics: Adult; Age Factors; Aged; Arginine; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Growth Hormone; Humans; Immunoenzyme Techniques; Middle Aged; Reference Values | 1989 |
[Growth hormone response to arginine administration in diabetics--with special reference to the multiple regression analysis in association with diabetic retinopathy].
Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Female; Follow-Up Studies; Growth Hormone; Humans; Male; Middle Aged; Obesity; Regression Analysis; Retrospective Studies | 1989 |
Alpha-adrenergic blockade improves glucose-potentiated insulin secretion in non-insulin-dependent diabetes mellitus.
Topics: Adrenergic alpha-Antagonists; Adult; Arginine; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 2; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Phentolamine; Propranolol | 1987 |
Beta-endorphin infusion restores acute insulin responses to glucose in type-2 diabetes mellitus.
Topics: Arginine; beta-Endorphin; Blood Glucose; Diabetes Mellitus, Type 2; Endorphins; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged | 1987 |
Islet beta-cell function and polymorphism in the 5'-flanking region of the human insulin gene.
Topics: Adult; Alleles; Arginine; Blood Glucose; Chromosome Mapping; Diabetes Mellitus, Type 2; DNA Restriction Enzymes; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Polymorphism, Genetic | 1985 |
Insulin treatment improves glucose-induced insulin release in rats with NIDDM induced by streptozocin.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Insulin; Insulin Secretion; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Abnormal calcium handling by perifused pancreatic islets from neonatal streptozotocin diabetic model rats.
Topics: Animals; Animals, Newborn; Arginine; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Insulin; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains | 1987 |
Disproportionate elevation of immunoreactive proinsulin in type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance.
Topics: Arginine; Blood Glucose; Dexamethasone; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Proinsulin | 1987 |
Plasma glucose lowering effect of sparteine sulphate infusion in non-insulin dependent (type 2) diabetic subjects.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Sparteine | 1988 |
In vitro response to mitogens and antigens in elderly and post-cytotoxic patients can be modified by a new hypoxanthine derivative (PCF-39).
Topics: Aged; Aging; Antineoplastic Agents; Arginine; Diabetes Mellitus, Type 2; Humans; Hypoxanthines; Immunity, Cellular; Lymphocyte Activation; Melanoma; Phytohemagglutinins | 1987 |
Arginine-stimulated acute phase of insulin secretion in non-insulin-dependent diabetes in the young.
Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin Secretion | 1986 |
Evidence for normal in vitro Ca2+-stimulated insulin release in rats with non-insulin-dependent diabetes.
Topics: Animals; Arginine; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1986 |
Inhibitory effect of enkephalin on insulin secretion in healthy subjects and in non insulin-dependent diabetic subjects.
Topics: Adult; Arginine; Blood Glucose; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Diabetes Mellitus, Type 2; Eating; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Male; Middle Aged | 1987 |
Growth hormone reserve in diabetes mellitus.
Topics: Adolescent; Adult; Arginine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Growth Hormone; Humans; Levodopa; Lipid Metabolism; Male | 1987 |
Abnormal glucose modulation of islet A- and B-cell responses to arginine in non-insulin-dependent diabetes mellitus.
Topics: Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Glucagon; Glucose; Humans; Insulin; Islets of Langerhans; Male; Middle Aged | 1985 |
C-peptide measurement in the differentiation of type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus.
Topics: Adolescent; Adult; Age Factors; Arginine; C-Peptide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Female; Glucose Tolerance Test; Humans; Indians, North American; Insulin; Male; White People | 1985 |
Insulin resistance and impaired insulin secretion in subjects with histories of gestational diabetes mellitus.
Topics: Adult; Arginine; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Epinephrine; Female; Glucagon; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Norepinephrine; Obesity; Pregnancy; Pregnancy in Diabetics | 1985 |
Pathophysiology of insulin secretion in diabetes mellitus.
Topics: Arginine; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Kinetics; Models, Biological; Reference Values | 1985 |
The mechanism of exaggerated glucagon response to arginine in diabetes mellitus.
Topics: Adult; Aged; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Infusion Systems; Kinetics; Middle Aged | 1985 |