arginine and DDPAC

arginine has been researched along with DDPAC in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (3.85)	29.6817
2010's	13 (50.00)	24.3611
2020's	12 (46.15)	2.80

Authors

Authors	Studies
Aburas, J; Brown, AEX; Fleming, AC; Gao, FB; Gendron, TF; Ghadge, G; Gu, Y; Islam, P; Kankel, MW; Kiskinis, E; Kratsios, P; Krishnan, G; Roos, RP; Sonobe, Y; Warren, EC	1
Cicardi, ME; Haeusler, AR; Jensen, BK; Krishnamurthy, K; Markandaiah, SS; Pasinelli, P; Russell, K; Sriramoji, S; Trotti, D; Verdone, BM; Wen, X	1
Barone, P; Cicarelli, G; Cuoco, S; Gagliardi, M; Pellecchia, MT; Procopio, R; Quattrone, A; Russillo, MC; Scarpa, A; Sorrentino, C; Talarico, M; Vinciguerra, C	1
Coyne, AN; Dafinca, R; Dasovich, M; Dawson, TM; Dawson, VL; DeJesus Hernandez, M; Dickson, D; Fouquerel, E; Gao, J; Gendron, TF; Girdhar, A; Guo, L; Kam, TI; Kang, BG; Leung, AKL; Liu, S; Lloyd, TE; Mewborne, QT; Petrucelli, L; Punathil, R; Rothstein, JD; Sheth, U; Shi, Z; Talbot, K; van Blitterswijk, M; Veire, A; Zhang, K; Zhang, YJ	1
Fairman, R; Lee, EB; Nelson, SCK; Viera Ortiz, AP; Zhang, Y	1
Arnold, FJ; Bennett, CL; Dastidar, S; Freibaum, BD; Joiner, W; La Spada, AR; McKinstry, SU; Seidner, G; Sopher, BL; Stockford, C; Taylor, JP; West, RJH; Wu, M	1
Cheng, W; Jiang, H; Jiang, L; Li, W; Li, Z; Liu, J; Liu, X; Lu, K; Qi, S; Sheng, J; Shu, X; Tang, D; Wang, K; Xu, L; Yan, C; Zhan, X; Zhang, T; Zhou, C	1
Odeh, HM; Shorter, J	1
Chen, S; Dong, J; Glynn, S; Li, S; Li, Y; Lu, B; Snyder, M; Tantray, I; Vogel, H; Wu, Z	1
Cha, IJ; Chung, CG; Ha, CM; Kim, ES; Kim, HJ; Kim, J; Kim, YH; Ko, BS; Lee, SB; Park, JH; Park, SS	1
Beckers, J; Boeynaems, S; Bullock, SL; Chandran, S; De Decker, M; Dedeene, L; Fazal, R; Fumagalli, L; Gitler, AD; Guo, W; Koch, P; Madan, V; McCampbell, A; Mehta, AR; Moisse, M; Poesen, K; Raitcheva, D; Selvaraj, BT; Swijsen, A; Thal, DR; van Blitterswijk, M; Van Damme, P; Van Den Bosch, L; Vanden Berghe, P; Vandoorne, T; Verfaillie, C; Young, FL	1
Babu, M; Becker, S; de Opakua, AI; Favretto, F; Rankovic, M; Zweckstetter, M	1
Lamitina, ST; Monaghan, J; Pandey, UB; Rudich, P; Snoznik, C; Watkins, SC	1
Goto, K; Ishikawa, T; Nakamura, K; Shimasaki, R; Umehara, F	1
Amaya, J; Burke, KA; Chabata, CV; Conicella, AE; Dignon, GL; Fawzi, NL; Mittal, J; Ryan, VH; Silva, R; Zerze, GH	1
Dardov, VJ; Farrer, LA; Ferry, R; Fraser, PE; Holt, CE; Kaminski Schierle, GS; Kaminski, CF; Klenerman, D; Knowles, T; Lin, JQ; Meadows, W; Miyashita, A; Phillips, EC; Qamar, S; Randle, SJ; Ruggeri, FS; Schmitt-Ulms, G; St George-Hyslop, P; Ströhl, F; Tartaglia, GG; Varela, JA; Vendruscolo, M; Wang, G; Williams, D	1
Hattori, S; Matsuoka, M; Shibagaki, Y; Suzuki, H	1
Abdi, Z; Adamson, G; Barnes, J; Beck, JA; Blair, M; Campbell, T; Clegg, SL; Collinge, J; Crutch, SJ; Druyeh, R; Fox, NC; Gambetti, P; Guerreiro, RJ; Harper, L; Kenny, J; Kretzschmar, H; Leung, KK; Lowe, J; Mahoney, CJ; Mead, S; Nicholas, JM; Ponto, C; Rohrer, JD; Rossor, MN; Rowe, JB; Schott, JM; Slattery, CF; Uphill, J; Warren, JD; Zerr, I	1
Ichida, JK; Krishnamurthy, K; Lin, S; Markandaiah, SS; Monaghan, J; Pandey, UB; Pasinelli, P; Shi, Y; Shneider, NA; Tan, W; Trotti, D; Wen, X; Westergard, T	1
Boeynaems, S; Bogaert, E; Callaerts, P; Cruts, M; Cuijt, I; De Baets, G; Gijselinck, I; Gitler, AD; Jovičić, A; Michiels, E; Robberecht, W; Rousseau, F; Scheveneels, W; Schymkowitz, J; Sieben, A; Steyaert, J; Van Broeckhoven, C; Van Damme, P; Van Den Bosch, L; Verstrepen, KJ	1
Almeida, S; Gao, FB; Gendron, TF; Karydas, A; Lopez-Gonzalez, R; Lu, Y; Miller, BL; Petrucelli, L; Tran, H; Yang, D	1
Chen, K; Li, X; Sun, L; Xiao, S	1
Cruchaga, C; Gitcho, MA; Goate, A; Robberecht, W; Seijo-Martínez, M; Van Damme, P; Vidal, JM; Wang, J; Wang, L; Wu, JY	1
Brewer, J; Davis, M; Kumar, KR; Mastaglia, FL; Mina, K; Needham, M; Ng, K; Staples, C; Sue, CM	1
Ahn, BY; Chang, YH; Kim, DS; Kim, EJ; Kim, HJ; Kim, HS; Kim, S; Kim, SJ; Lee, HW; Park, YE; Seeley, WW	1
Anfossi, M; Bernardi, L; Bruni, AC; Colao, R; Costanzo, A; Curcio, SA; Frangipane, F; Gallo, M; Geracitano, S; Iapaolo, D; Maletta, RG; Mirabelli, M; Puccio, G; Smirne, N; Tomaino, C	1

Reviews

1 review(s) available for arginine and DDPAC

Article	Year
Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD. Emerging topics in life sciences, 2020, 12-11, Volume: 4, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Arginine; C9orf72 Protein; Dipeptides; DNA Repeat Expansion; Frontotemporal Dementia; Humans; Proteomics	2020

Other Studies

25 other study(ies) available for arginine and DDPAC

Article	Year
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation. Nature communications, 2021, 10-15, Volume: 12, Issue:1 Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabditis elegans; Dipeptides; Female; Frontotemporal Dementia; Gene Editing; Gene Knockdown Techniques; Glycine; HEK293 Cells; Humans; Middle Aged; Motor Neurons; Nerve Degeneration; Proline	2021
A mouse model with widespread expression of the C9orf72-linked glycine-arginine dipeptide displays non-lethal ALS/FTD-like phenotypes. Scientific reports, 2022, 04-04, Volume: 12, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Dipeptides; Female; Frontotemporal Dementia; Glycine; Male; Mice; Phenotype	2022
A novel phenotype in an Italian family with a rare progranulin mutation. Journal of neurology, 2022, Volume: 269, Issue:11 Topics: Arginine; Dysphonia; Dystonia; Frontotemporal Dementia; Histidine; Humans; Intercellular Signaling Peptides and Proteins; Mutation; Phenotype; Progranulins; Respiratory Sounds	2022
Poly(ADP-ribose) promotes toxicity of Science translational medicine, 2022, 09-14, Volume: 14, Issue:662 Topics: Arginine; C9orf72 Protein; Dipeptides; DNA-Binding Proteins; Frontotemporal Dementia; Humans; Poly Adenosine Diphosphate Ribose	2022
C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities. Journal of neuropathology and experimental neurology, 2023, 10-20, Volume: 82, Issue:11 Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Dipeptides; DNA Repeat Expansion; Drosophila melanogaster; Frontotemporal Dementia; Humans; Proline; Proteasome Endopeptidase Complex; Proteolysis	2023
Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity. Acta neuropathologica communications, 2023, 10-17, Volume: 11, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Dipeptides; DNA Helicases; DNA Repeat Expansion; Drosophila; Frontotemporal Dementia; HEK293 Cells; Humans; Motor Neurons; Multifunctional Enzymes; RNA; RNA Helicases	2023
Cryo-EM structure of C9ORF72-SMCR8-WDR41 reveals the role as a GAP for Rab8a and Rab11a. Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-05, Volume: 117, Issue:18 Topics: Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Arginine; Autophagy; Autophagy-Related Proteins; C9orf72 Protein; Carrier Proteins; Cryoelectron Microscopy; Filamins; Frontotemporal Dementia; Genetic Predisposition to Disease; GTPase-Activating Proteins; Humans; Multiprotein Complexes; rab GTP-Binding Proteins; Sequence Alignment	2020
Quality-control mechanisms targeting translationally stalled and C-terminally extended poly(GR) associated with ALS/FTD. Proceedings of the National Academy of Sciences of the United States of America, 2020, 10-06, Volume: 117, Issue:40 Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; ATPases Associated with Diverse Cellular Activities; C9orf72 Protein; Disease Models, Animal; DNA Repeat Expansion; Drosophila melanogaster; Drosophila Proteins; Frontotemporal Dementia; HEK293 Cells; Humans; Metalloendopeptidases; Mitochondria; Mitochondrial Proteins; Protein Biosynthesis; Proteome; Receptors, Notch; Ribosomes; Signal Transduction	2020
C9orf72-associated arginine-rich dipeptide repeats induce RNA-dependent nuclear accumulation of Staufen in neurons. Human molecular genetics, 2021, 06-09, Volume: 30, Issue:12 Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Cell Nucleus; Cytoplasm; Dipeptides; Disease Models, Animal; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Frontotemporal Dementia; Gene Knockdown Techniques; Heterogeneous-Nuclear Ribonucleoprotein Group F-H; Humans; Neurons; Nuclear Localization Signals; RNA; RNA Processing, Post-Transcriptional; RNA-Binding Proteins	2021
Science advances, 2021, Volume: 7, Issue:15 Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Axonal Transport; C9orf72 Protein; Dipeptides; DNA Repeat Expansion; Drosophila; Frontotemporal Dementia; Humans; Microtubules; Motor Neurons	2021
Proline/arginine dipeptide repeat polymers derail protein folding in amyotrophic lateral sclerosis. Nature communications, 2021, 06-07, Volume: 12, Issue:1 Topics: Amyotrophic Lateral Sclerosis; Arginine; Biopolymers; Brain; C9orf72 Protein; Catalytic Domain; Crystallography, X-Ray; Dipeptides; DNA Repeat Expansion; Frontotemporal Dementia; Humans; Nuclear Magnetic Resonance, Biomolecular; Peptidylprolyl Isomerase; Proline; Protein Aggregates; Protein Binding; Protein Folding; Recombinant Proteins; Repetitive Sequences, Amino Acid	2021
Nuclear localized C9orf72-associated arginine-containing dipeptides exhibit age-dependent toxicity in C. elegans. Human molecular genetics, 2017, 12-15, Volume: 26, Issue:24 Topics: Age Factors; Alanine; Amyotrophic Lateral Sclerosis; Animals; Arginine; C9orf72 Protein; Caenorhabditis elegans; Cell Nucleus; Dipeptides; Disease Models, Animal; DNA Repeat Expansion; Frontotemporal Dementia; Gene Expression Regulation; Genes, Regulator; Motor Neurons; Mutation	2017
[A case of mitochondrial disease with multiple mitochondrial DNA deletions suspected amyotrophic lateral sclerosis-frontotemporal dementia]. Rinsho shinkeigaku = Clinical neurology, 2018, Jan-26, Volume: 58, Issue:1 Topics: Aged; Amyotrophic Lateral Sclerosis; Arginine; Diagnosis, Differential; DNA, Mitochondrial; Fatal Outcome; Female; Frontotemporal Dementia; Gene Deletion; Humans; Mitochondria, Muscle; Mitochondrial Diseases; Muscle, Skeletal	2018
Mechanistic View of hnRNPA2 Low-Complexity Domain Structure, Interactions, and Phase Separation Altered by Mutation and Arginine Methylation. Molecular cell, 2018, 02-01, Volume: 69, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Arginine; Frontotemporal Dementia; Heterogeneous-Nuclear Ribonucleoprotein Group A-B; Humans; Inclusion Bodies; Magnetic Resonance Imaging; Methylation; Mutation; Neurons; Protein Processing, Post-Translational	2018
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions. Cell, 2018, 04-19, Volume: 173, Issue:3 Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Cations; DNA Methylation; Frontotemporal Dementia; Frontotemporal Lobar Degeneration; Humans; Microscopy, Atomic Force; Microscopy, Fluorescence; Molecular Chaperones; Protein Binding; Protein Domains; Protein Processing, Post-Translational; Protein Structure, Secondary; RNA-Binding Protein FUS; Tyrosine; Xenopus laevis	2018
The proline-arginine repeat protein linked to C9-ALS/FTD causes neuronal toxicity by inhibiting the DEAD-box RNA helicase-mediated ribosome biogenesis. Cell death & disease, 2018, 09-24, Volume: 9, Issue:10 Topics: Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Arginine; C9orf72 Protein; Cell Line, Tumor; Cell Survival; DEAD-box RNA Helicases; Dipeptides; Frontotemporal Dementia; HEK293 Cells; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred ICR; Microsatellite Repeats; Neurons; Proline; Ribosomes; RNA, Ribosomal	2018
R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association, 2014, Volume: 10, Issue:6 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arginine; Brain; Cohort Studies; Creutzfeldt-Jakob Syndrome; Exons; Female; Frontotemporal Dementia; Genetic Predisposition to Disease; Genetic Variation; Genome-Wide Association Study; Genotype; Histidine; Humans; Male; Membrane Glycoproteins; Middle Aged; Phenotype; Receptors, Immunologic; Risk Factors	2014
Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death. Neuron, 2014, Dec-17, Volume: 84, Issue:6 Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Antisense Elements (Genetics); Arginine; C9orf72 Protein; Cell Death; Dipeptides; DNA Repeat Expansion; Drosophila melanogaster; Frontotemporal Dementia; Humans; Motor Neurons; Neurons; Primary Cell Culture; Proline; Protein Aggregation, Pathological; Proteins; Spinal Cord	2014
Drosophila screen connects nuclear transport genes to DPR pathology in c9ALS/FTD. Scientific reports, 2016, Feb-12, Volume: 6 Topics: Active Transport, Cell Nucleus; Amyotrophic Lateral Sclerosis; Animals; Arginine; Cell Nucleus; Dipeptides; Disease Models, Animal; Drosophila melanogaster; Eye; Frontotemporal Dementia; Genes, Insect; Genetic Testing; HeLa Cells; Humans; Methylation; Repetitive Sequences, Amino Acid; RNA Interference	2016
Poly(GR) in C9ORF72-Related ALS/FTD Compromises Mitochondrial Function and Increases Oxidative Stress and DNA Damage in iPSC-Derived Motor Neurons. Neuron, 2016, Oct-19, Volume: 92, Issue:2 Topics: Amyotrophic Lateral Sclerosis; Arginine; Blotting, Western; C9orf72 Protein; Cell Line; Dipeptides; DNA Damage; DNA Repeat Expansion; Frontotemporal Dementia; Glycine; Humans; Induced Pluripotent Stem Cells; Mitochondria; Motor Neurons; Oxidative Stress; Proteins; Tumor Suppressor Protein p53	2016
Rapidly Progressive Frontotemporal Dementia Associated with MAPT Mutation G389R. Journal of Alzheimer's disease : JAD, 2017, Volume: 55, Issue:2 Topics: Adult; Arginine; Binding Sites; Frontotemporal Dementia; Genetic Association Studies; Genetic Testing; Glycine; Humans; Magnetic Resonance Imaging; Male; Methylation; Models, Molecular; Mutation; tau Proteins	2017
Pathogenic cysteine mutations affect progranulin function and production of mature granulins. Journal of neurochemistry, 2010, Volume: 112, Issue:5 Topics: Animals; Arginine; Axons; Brain; Cell Enlargement; Cell Line, Transformed; Cysteine; Dithiothreitol; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Family Health; Frontotemporal Dementia; Gene Expression Regulation; Genetic Predisposition to Disease; Green Fluorescent Proteins; Humans; Intercellular Signaling Peptides and Proteins; Motor Neurons; Mutation; Neurites; Pancreatic Elastase; Progranulins; Rats; Rats, Wistar; RNA, Messenger; Transfection; Tyrosine	2010
Two Australian families with inclusion-body myopathy, Paget's disease of bone and frontotemporal dementia: novel clinical and genetic findings. Neuromuscular disorders : NMD, 2010, Volume: 20, Issue:5 Topics: Adenosine Triphosphatases; Adult; Alkaline Phosphatase; Arginine; Australia; Cell Cycle Proteins; Creatine Kinase; Electrodiagnosis; Family Health; Female; Frontotemporal Dementia; Humans; Inclusion Bodies; Leucine; Magnetic Resonance Imaging; Male; Middle Aged; Muscle, Skeletal; Muscular Diseases; Mutation; Osteitis Deformans; Tryptophan; Valosin Containing Protein	2010
Inclusion body myopathy with Paget disease of bone and frontotemporal dementia linked to VCP p.Arg155Cys in a Korean family. Archives of neurology, 2011, Volume: 68, Issue:6 Topics: Adenosine Triphosphatases; Aged; Amino Acid Substitution; Arginine; Asian People; Cell Cycle Proteins; Cysteine; Female; Frontotemporal Dementia; Genetic Linkage; Humans; Male; Middle Aged; Mutation, Missense; Myositis, Inclusion Body; Osteitis Deformans; Pedigree; Valosin Containing Protein	2011
Novel PSEN1 and PGRN mutations in early-onset familial frontotemporal dementia. Neurobiology of aging, 2009, Volume: 30, Issue:11 Topics: Adult; Arginine; Cysteine; DNA Mutational Analysis; Family Health; Female; Fluorodeoxyglucose F18; Frontotemporal Dementia; Genetic Predisposition to Disease; Humans; Intercellular Signaling Peptides and Proteins; Male; Microtubule-Associated Proteins; Middle Aged; Mutation; Presenilin-1; Progranulins; Radionuclide Imaging	2009