arginine has been researched along with Blood Clot in 259 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (7.34) | 18.7374 |
| 1990's | 65 (25.10) | 18.2507 |
| 2000's | 104 (40.15) | 29.6817 |
| 2010's | 58 (22.39) | 24.3611 |
| 2020's | 13 (5.02) | 2.80 |
| Authors | Studies |
|---|---|
| González-Rodríguez, M; Lázaro-García, A; Llamas-Sillero, P; Martínez-Alfonzo, I; Tomás-Mallebrera, M; Velasco-Rodríguez, D; Vidal-Laso, R | 1 |
| Blacker, DJ; Edwards, AB; Knuckey, NW; Meloni, BP | 1 |
| Asmis, LM; Bachler, M; Fries, D; Koscielny, J; Lang, T; Nowak, H; Paulus, P; Schewe, JC; von Heymann, C | 1 |
| Chen, R; Guo, Y; Huang, Y; Jiang, J; Li, Y; Ren, J; Zhao, Q; Zhou, J | 1 |
| Belizna, C; Djokovic, A; Dopsaj, V; Marisavljevic, D; Markovic, O; Saponjski, D; Saponjski, J; Stanisavljevic, N; Stojanovich, L; Todic, B; Zdravkovic, M | 1 |
| Butler, A; Gudgin, E; Mindlina, I; Nelmes, E; Sharp, M; Thomas, W | 1 |
| Jindong, H; Na, L | 1 |
| Singh Lubana, S; Singh, N; Tsai, HM | 1 |
| Curtis, BR; Erdil, RM; Gilyard, SN; Knelson, EH; Leaf, RK; Malhotra, R; Puram, RV; Ranganathan, R; Van Beuningen, AM; Wallwork, R; Weber, BN | 1 |
| Boyle, G; Buchholz, H; Cantor, RS; Conway, J; Fynn-Thompson, F; Griffiths, E; Hawkins, B; Lorts, A; Lytrivi, ID; Machado, D; May, L; Niebler, RA; Rossano, J; Sutcliffe, DL; VanderPluym, CJ | 1 |
| Enright, H; Fahy, A; McGlynn, F; McGrath, J; McHugh, J; Ryan, B; Varghese, C | 1 |
| Gandotra, P; Garra, G; Gruberg, L; Selim, S; Supariwala, A | 1 |
| Bartlett, RH; Bellomo, TR; Jeakle, MA; Major, TC; Meyerhoff, ME | 1 |
| Agrati, C; Beccacece, A; Bibas, M; Bordoni, V; Casetti, R; Cimini, E; Garotto, G; Gili, S; Grassi, G; Ippolito, G; Marchioni, L; Mariotti, D; Nicastri, E; Notari, S; Sacchi, A; Tartaglia, E | 1 |
| Male, C; van Ommen, CH; Young, G | 1 |
| Abramov, D; Birks, E; Bitar, A; Lenneman, A; Massey, T; Slaughter, M; Vijayakrishnan, R | 1 |
| Lopez, ND; Sin, JH | 1 |
| Greinacher, A; Heid, J; Katus, HA; Müller, OJ | 1 |
| Gleichgerrcht, E; Lim, MY; Turan, TN | 1 |
| Faraoni, D; Koster, A; Levy, JH | 1 |
| Abbott, M; Abdi, M; Chauhan, N; Chin, M; Fucci, QA; Halim, A; Handy, DE; Lim, K; Loscalzo, J; Lu, TS; Mistri, M; Pang, P; Proctor, B; Siedlecki, AM; Wang, B; Yin, W | 1 |
| Gheysens, O; Goffin, KE; Hoylaerts, MF; Jacquemin, M; Liesenborghs, L; Peerlinck, K; Peetermans, M; Peetermans, WE; Vanassche, T; Verhaegen, J; Verhamme, P; Wijngaerden, EV | 1 |
| Fu, X; Ning, JP | 1 |
| Ascaso, M; Pereda, D; Quintana, E; Sandoval, E | 1 |
| Ahadizadeh, EN; Buethe, DJ; Honda, K; Manzoor, NF; Merati, M; Mowry, SE; Semaan, M | 1 |
| Forman, DA; Mohanty, E; Nazir, S; Sheppard, JI; Warkentin, TE | 1 |
| Burger, CF; Schlesinger, JJ | 1 |
| Cao, FF; Feng, X; Jiao, RN; Zhang, HT | 1 |
| Fan, Q; Geng, P; Li, W; Li, Y; Lin, L; Song, L; Wang, N | 1 |
| Hatakeyama, M; Munakata, M; Ono, Y | 1 |
| Cervera, A; Chamorro, Á; de la Rosa, X; Durduran, T; Justicia, C; Kristoffersen, AK; Planas, AM; Valdés, CP; Varma, HM | 1 |
| Annich, GM; Bartlett, RH; Brisbois, EJ; Handa, H; Jones, AM; Major, TC; Zanetti, ME | 1 |
| Forsyth, LL; Shannon, F; Sheppard, JA; Smith, MD; Smythe, MA; Warkentin, TE | 1 |
| Davison, SP; Endara, M; Shuck, J | 1 |
| Hillebrand, J; Martens, S; Mesters, R; Scherer, M; Schmidt, C; Sindermann, J | 1 |
| Ito, S; McAlister, RK | 1 |
| Li, Q; Peng, J; Wei, S; Wu, W; Zhou, J | 1 |
| Chi, Y; Duan, T; Rong, Y; Shao, Y; Wang, Y; Xia, W | 1 |
| Young, G | 1 |
| Agewall, S; Atar, D; Drexel, H; Husted, SE; Kaski, JC; Kjeldsen, K; Koller, L; Lewis, BS; Lip, GYH; Morais, J; Niessner, A; Storey, RF; Tamargo, J; Torp-Pedersen, C; Verheugt, FWA; Wassmann, S | 1 |
| Imoto, K; Isoda, S; Karube, N; Masuda, M; Matsuki, Y; Uchida, K; Yasuda, S | 1 |
| Cervar-Zivkovic, M; Eberhard, K; Kolovetsiou-Kreiner, V; Lang, U; Mayer-Pickel, K; Mörtl, MG; Obermayer-Pietsch, B; Schlembach, D | 1 |
| Chen, XL; Gao, XR; Lao, MC; Liu, LJ; Lu, GH; Luo, CF; Zhai, YS | 1 |
| Albánez, S; Gould, TJ; James, PD; Liaw, PC; Lillicrap, D; Mewburn, J; Michels, A; Nesbitt, K; Swystun, LL | 1 |
| Lei, BZ; Sendowski, M; Shatzel, JJ | 1 |
| Baumgarten, G; Kim, S; Koster, A; Riedel, R; Schewe, JC; Schmieder, A | 1 |
| Alarcón Pérez, L; Duque González, P; Rodríguez Huerta, AM | 1 |
| Hursting, MJ; Murray, PT | 2 |
| Lineaweaver, WC; Oswald, TM; Schleich, AR | 1 |
| Janssens, U; Kroner, S; Lejczyk, J; Niedeggen, A; Reith, S; Stortz, C | 1 |
| Chen, W; Liang, Z; Liu, H; Qu, X; Song, Y; Xia, W | 1 |
| Hursting, MJ; Jang, IK | 2 |
| Hursting, MJ; Verme-Gibboney, CN | 1 |
| Beyer, J; Halbritter, K; Schellong, S; Weise, M | 1 |
| Chong, BH; Isaacs, A | 1 |
| Matsuo, T; Sugimoto, T; Wanaka, K | 1 |
| Hursting, MJ; Soffer, J | 1 |
| Aloia, TA; Goss, JA | 1 |
| Asada, Y; Imamura, T; Kitamura, K; Matsuda, S; Matsumoto, T; Moriguchi-Goto, S; Shima, M; Sugita, C; Sumi, T; Takahashi, M; Yamashita, A | 1 |
| Buerke, M; Friedrich, I; Hamilton, K; Hauroeder, B; Linde, T; Maegdefessel, L; Michel, T; Raaz, U; Schlitt, A; Schubert, S; Steinseifer, U; Werdan, K | 1 |
| Chong, BH; Lip, GYH; Shantsila, E | 1 |
| Adamo, MF; Alagha, A; Chubb, AJ; Moman, E; Nolan, KB | 1 |
| Dhillon, S | 1 |
| Balasubramaniam, M; Forsyth, LL; Koerber, JM; Mattson, JC; Priziola, JL; Smythe, MA | 1 |
| Ichinoe, M; Mikami, T; Okayasu, I; Suzuki, K; Ujiie, S | 1 |
| Heil, S | 1 |
| Barash, P; Coady, M; Fareed, J; Genzen, JR; Hoppensteadt, D; Kurup, V; Wu, YY | 1 |
| Ding, H; Hui, R; Lu, Z; Shaffer, JR; Wang, DW; Wang, H; Wang, X; Wu, B; Yan, J | 1 |
| Buerke, M; Busshardt, M; Ebelt, H; Kaeberich, A; Maegdefessel, L; Plehn, A; Raaz, U; Russ, M; Schlitt, A; Schubert, S; Werdan, K | 1 |
| Alatri, A; Foramitti, M; Paoletti, O; Testa, S; Zimmermann, A | 1 |
| Bark, N; Blombäck, M; He, S; Johnsson, H; Wallén, NH | 1 |
| Buerke, M; Desaga, M; Genth-Zotz, S; Gulba, DC; Harder, S; Heyndrickx, GR; Rau, M; Rössig, L; Schneider, T; Zeiher, AM | 1 |
| Bentley, P; Sharma, P | 1 |
| Bartholomew, JR; Frame, JN; Rice, L; Whelton, A | 1 |
| Agnihotri, AK; Hoffman, WD; Jang, IK; Nam, KH; Yeh, RW; Yoon, JH | 1 |
| Bandyk, DF; Bartholomew, JR; Boyce, SW; Frame, JN; Rice, L | 1 |
| Fareed, J; Hoppensteadt, DA; Jeske, WP; Lewis, B; Walenga, JM | 1 |
| Boshkov, LK; Boyle, DA; Cox, DS; Hursting, MJ; Kallender, H; Raffini, LJ; Soffer, J; Sullivan, JE; Tarka, EA; Young, G | 1 |
| Donovan, JL; Kanaan, AO; Tran, MT | 1 |
| Hirano, K; Hirano, M; Kameda, K; Kikkawa, Y; Matsuo, S; Sasaki, T | 1 |
| Katzfuss, J; Klar, E; Lindenblatt, N; Püschel, A; Vollmar, B | 1 |
| Baglin, TP; Garcia, DA; Samama, MM; Weitz, JI | 1 |
| Demma, LJ; Levy, JH; Paciullo, CA | 1 |
| Gulseth, MP; Hellwig, TR; Peitz, GJ | 1 |
| Eno, S; Hondo, T; Iwamoto, A; Kimura, M; Matsuda, K; Matsumura, H | 1 |
| Cruz-González, I; López-Jiménez, R; Perez-Rivera, A; Yan, BP | 1 |
| Coppens, M; Eikelboom, JW; Gustafsson, D; Hirsh, J; Weitz, JI | 1 |
| Alasady, M; Brooks, AG; Gan, C; Kalman, JM; Kistler, PM; Lau, DH; Leong, DP; Lim, HS; Sanders, P; Schultz, C; Willoughby, SR; Worthley, MI; Young, GD | 1 |
| Mizuno, Y; Noda, K; Tanaka, R; Urabe, T | 1 |
| Cohen, M; Hursting, MJ; Lewis, BE; Leya, F; Matthai, WH; Moses, JW | 1 |
| Bittl, JA | 1 |
| Greinacher, A; Lubenow, N | 1 |
| Davis, MR; Ignarro, LJ; Kashyap, VS; Kerby, JD; Ortegon, DP | 1 |
| Chhablani, N; Laffan, M; Lane, DA; Olson, ST; Raja, SM; Swanson, R; Thompson, E | 1 |
| Kato, H; Kimura, S; Nakagawa, K; Nakagawa, M; Tsuji, H; Ukimura, N; Yamada, K; Yamada, Y; Yano, S | 1 |
| Giddings, JC; Hashimoto, M; Matsuo, O; Oiwa, K; Okada, K; Okada, Y; Okamoto, S; Ueshima, S; Yamamoto, J | 1 |
| Walenga, JM | 1 |
| LaMonte, MP | 1 |
| Dahlbäck, B | 2 |
| Peng, S; Tang, Z; Wang, Y; Xiao, Y; Zhao, M | 1 |
| de Denus, S; Spinler, SA | 1 |
| Buijsman, R; Meuleman, DG; Princen, AW; Smit, MJ; Van Dinther, TG; Vogel, GM | 1 |
| CHAMBERS, DA; SALZMAN, EW | 1 |
| Greinacher, A | 1 |
| Arruda, MJ; Cetta, F; Graham, LC; Walenga, JM; Wrona, LL | 1 |
| Heddle, N; Hirsh, J; Kelton, JG | 1 |
| Itoh, T; Naito, K; Natsuaki, M; Ohtsubo, S; Okazaki, Y; Rikitake, K | 1 |
| Dager, WE; Gosselin, RC; Owings, JT | 1 |
| Fritsma, GA | 1 |
| Goto, S; Ishida, H; Tamura, N | 1 |
| Hayashi, T; Kaneko, M; Nakao, Y; Nomura, T; Nonaka, Y; Okamura, J; Suyama, Y | 1 |
| Loscalzo, J | 1 |
| Nakagawa, P; Nugent, DJ; Yonekawa, KE; Young, G | 1 |
| de Groot, PG; de Laat, B; Derksen, RH; Urbanus, RT | 1 |
| Warkentin, TE | 1 |
| Aranki, SF; Fitzgerald, D; Gasparovic, H; Nathan, NS | 1 |
| Ferrell, J; Grossman, EJ; Hammes, MS; Hursting, MJ; Murray, PT; Reddy, BV; Shamp, TR; Swan, SK; Tang, I; Trevino, S | 1 |
| White, CM | 1 |
| Bhatt, DL; Gurm, HS | 1 |
| Bartholomew, JR | 1 |
| Woodyard, DN | 1 |
| Kam, PC; Kaur, N; Thong, CL | 1 |
| Alfrey, EJ; Braun, J; Dawson, L; Dick, A; Farrell, C; Lerner, SM; Pagano, CR; Smith, MA; Valenia, T | 1 |
| Kawano, HA; Nakajima, T; Suzuki, J; Tomaru, T; Tsujiuchi, Y; Uchida, Y | 1 |
| Bartholomew, JR; Hursting, MJ | 1 |
| Abrams, CS; Pollak, ES | 1 |
| Büller, HR; Di Nisio, M; Middeldorp, S | 1 |
| Chesebro, JH; Grill, DE; Hassinger, NL; McBane, RD; Mruk, JS | 1 |
| Pengo, V | 1 |
| Katz, E; Kim, KY; McNulty, I | 1 |
| Boshkov, L; Giacomuzzi, C; Mejak, B; Shen, I; Ungerleider, R | 1 |
| Dubb, J; Hursting, MJ; Verme-Gibboney, CN | 1 |
| Graff, J; Harder, S | 1 |
| Pendleton, R; Rodgers, GM; Wheeler, MM | 1 |
| Baxi, SM; Chi, L; Gould, WR; Johnson, TR; Leadley, RJ; McClanahan, TB; Saiya-Cork, K; Welch, KM | 1 |
| Daniels, B; Hiebert, LM; Linhardt, RJ; Mao, W; Wice, SM; Zhang, F | 1 |
| Hursting, MJ; Levine, RL; McCollum, D | 1 |
| Warkentin, TW | 1 |
| Hursting, MJ; Levine, RL; Lewis, BE; Leya, F; Wallis, DE | 1 |
| Brunini, TM; da Silva, CD; Mendes-Ribeiro, AC; Moss, MB; Santos, SF; Siqueira, MA | 1 |
| Chen, CY; Cooley, BC; Schmeling, G | 1 |
| Das, P; Hamdalla, H; Jozic, J; Moliterno, DJ; Mukherjee, D; Steinhubl, SR; Ziada, K | 1 |
| Battastini, AM; Edelweiss, MI; Iturry-Yamamoto, GR; Martins, NL; Picon, PD; Ribeiro, JP; Sarkis, JJ | 1 |
| Funaki, B; Van Ha, TG; Zangan, SM | 1 |
| Chandrasekharan, UM; Dicorleto, PE; Kashyap, VS; Kinney, CM; Lewis, CM; Yang, L | 1 |
| Hursting, MJ; Lewis, BE | 1 |
| Haas, S; Höhnke, C | 1 |
| Kloecker, GH; Laber, DA; Martin, ME | 1 |
| Greinacher, A; Selleng, K; Warkentin, TE | 1 |
| Dager, WE; Dougherty, JA; Militello, MA; Nguyen, PH; Smythe, MA | 1 |
| Bong, M; Di Cesare, PE; Patel, VP | 1 |
| Blankenberg, S; Schnabel, R | 1 |
| Hamada, M; Matsui, H; Mizuno, T; Shida, Y; Sugimoto, M; Yoshioka, A | 1 |
| Lepor, NE | 1 |
| Bozlar, U; Simsek, S; Turba, UC | 1 |
| Diez-Ewald, M | 1 |
| Chen, JR; Liu, Y; Wu, F; Yang, Y | 1 |
| Rolfes, C; Steinfeldt, T | 1 |
| Allegretto, N; Barbera, F; Bird, JE; Giancarli, MR; Ogletree, ML; Schumacher, WA; Seiffert, D; Wong, P | 1 |
| Chen, Y; Cui, G; Lee, KH; Morris-Natschke, S; Peng, S; Qian, K; Wang, C; Zhao, M | 1 |
| Berman, HJ | 1 |
| Brüggener, E; Hauptmann, J; Müller, H | 1 |
| Brotherton, AA; Czervionke, RL; Fry, GL; Haycraft, DL; Hoak, JC | 1 |
| Hoffmann, J; Markwardt, F; Nowak, G | 1 |
| Bastida, E; Escolar, G; Jamieson, GA; Ordinas, A | 1 |
| Markwardt, F | 1 |
| Hijikata, A; Kikumoto, R; Ohkubo, K; Okamoto, S; Tamao, Y; Tezuka, T; Tonomura, S | 1 |
| Moncada, S; Radomski, MW | 1 |
| Gryglewski, RJ; Swies, J | 1 |
| Nakashima, M; Nishiyama, H; Saniabadi, AR; Takiguchi, Y; Uematsu, T; Umemura, K | 1 |
| Fujino, H; Ikeda, K; Kubota, A; Nara, Y; Numano, F; Tagami, M; Yamori, Y | 1 |
| Berry, CN; Girard, D; Lecoffre, C; Lochot, S | 1 |
| Tuddenham, EG | 1 |
| Bauer, KA; Eichinger, S; Greengard, JS; Griffin, JH | 1 |
| Raij, L; Shultz, PJ; Westberg, G | 1 |
| Raij, L | 1 |
| De Waele, M; Jochmans, K; Liebaers, I; Lissens, W; Peeters, S; Vervoort, R | 1 |
| Gryglewski, RJ; Korbut, R; Ocetkiewicz, A | 1 |
| Matsuoka, A; Sasaki, Y; Yamamoto, J; Yamashita, T | 1 |
| Iijima, K; Kaneko, M; Matsuda, M; Mimuro, J; Muramatsu, S; Nakamura, K; Sakata, Y; Yoshitake, S | 1 |
| Bignell, P; Cooper, DN; Grundy, CB; Kakkar, VV; Martin, R; Millar, DS; Moffat, EH | 1 |
| Hirase, T; Matsuo, T; Miki, T; Sakamoto, S; Suzuki, S; Tsukamoto, T; Yamada, T | 1 |
| Kawai, H; Tamao, Y | 1 |
| Hamaguchi, M; Kagami, K; Katsumi, A; Kojima, T; Okamoto, Y; Saito, H; Sugiura, I; Takamatsu, J; Yamazaki, T | 1 |
| Figliuzzi, M; Gaspari, F; Macconi, D; Noris, M; Paris, S; Remuzzi, G; Ruggenenti, P; Todeschini, M; Zoja, C | 1 |
| Födinger, M; Hörl, WH; Koizar, D; Mannhalter, C; Pabinger, I; Rintelen, C; Sunder-Plassmann, G | 1 |
| Borchiellini, A; Montaruli, B; Muleo, G; Pannocchia, A; Schinco, P; Tamponi, G; van Mourik, JA; Voorberg, J | 1 |
| Berry, CN; Gauffeny, C; Lecoffre, C; Lunven, C; O'Brien, DP; Roome, NO | 1 |
| Donkin, J; Iaffaldano, R; Lewis, BE; McKiernan, TL; Rao, L; Wallenga, JM | 1 |
| Heran, CL; Schumacher, WA; Steinbacher, TE | 1 |
| Berry, CN; Girard, D; Girardot, C; Lochot, S; Lunven, C; Visconte, C | 1 |
| Börjesson, I; Elg, M; Gustafsson, D; Lenfors, S; Teger-Nilsson, AC | 1 |
| Kinjoh, K; Kosugi, T; Masuda, Y; Nakamura, M; Sunagawa, M; Yamashita, S | 1 |
| Ikeda, Y; Moriki, T; Murata, M; Ono, F; Tokuhira, M; Watanabe, K; Watanabe, R; Yokoyama, K; Zama, T | 1 |
| Aoki, N; Fujimori, Y; Morita, T; Nakamura, F; Omata, M; Sakamoto, Y; Tomaru, T; Uchida, Y | 1 |
| Aiach, M; Aillaud, MF; Alhenc-Gelas, M; Berruyer, M; de Moerloose, P; Dreyfus, M; Emmerich, J; Fiessinger, JN; Garcin, JM; Jude, B; Juhan-Vague, I; Le Querrec, A; Priollet, P; Vallantin, X; Wolf, M | 1 |
| Giddings, JC; Kawano, M; Sasaki, Y; Watanabe, S; Yamamoto, J | 1 |
| Lewis, BE; Walenga, JM; Wallis, DE | 1 |
| Kambayashi, J; Kawasaki, T; Kim, DI; Sakon, M; Shibuya, T | 1 |
| Berkane, N; Boulanger, H; Pruna, A | 1 |
| Fareed, J; Hoppensteadt, DA; Kahn, S | 1 |
| Hara, T; Kunitada, S; Morishima, Y; Tanabe, K; Terada, Y | 1 |
| Brennan, SO; George, PM; Hammonds, B; Spearing, R | 1 |
| Baglin, C; Baglin, T; Brown, K; Luddington, R; Williamson, D | 1 |
| Fareed, J; Lewis, BE; Rangel, Y | 1 |
| Berry, CN; Charles, MC; Ferrari, P; Girard, D; Girardot, C; Lechaire, I; Lunven, C; O'Brien, DP | 1 |
| Hirayama, F; Hisamichi, N; Kawasaki, T; Koshio, H; Matsumoto, Y; Sato, K; Taniuchi, Y | 1 |
| Deschenes, I; DiMaio, J; Finkle, CD; Leblond, L; St Pierre, A; Winocour, PD | 1 |
| Griffin, JH; Petäjä, JM | 1 |
| Berry, CN; Girardot, C; Lechaire, I; Lunven, C; O'Connor, SE | 1 |
| Koide, M; Matsuo, T | 1 |
| Fukazawa, T; Goto, Y; Hayashi, H; Inoue, Y; Komatsu, Y | 1 |
| Bauters, C; Bertrand, ME; Corseaux, D; Dupuis, B; Lablanche, JM; Le Tourneau, T; Lebuffe, G; McFadden, E; Vallet, B; Van Belle, E | 1 |
| Giddings, JC; Noguchi, T; Sasaki, Y; Seki, J; Yamamoto, J | 1 |
| Matthai, WH | 1 |
| Inoue, S; Kawata, S; Kayanoki, Y; Kiso, S; Matsuzawa, Y; Tamura, S; Taniguchi, N; Yamasaki, E | 1 |
| Allen, MC; Ambler, J; Brundish, D; Bull, A; Butler, K; Donovan, V; Fullerton, JD; Garman, SM; Hayler, JF; Howarth, G; Hoyle, W; Janus, D; Kane, PD; McDonnell, M; Smith, GP; Talbot, MD; Wakeford, R; Walker, CV | 1 |
| Laffan, M; Manning, R; Mille-Baker, B; Mumford, A; Vakalopoulou, S | 1 |
| Kobayakawa, N; Morita, T; Nakamura, F; Onitake, A; Tomaru, T; Uchida, Y | 1 |
| Jang, IK; Sabatine, MS; Tu, TM | 1 |
| Aisaka, K; Hayashi, M; Matsuo, A; Nakamoto, H | 1 |
| Vlasov, TD | 1 |
| Baglin, TP | 1 |
| Fleischer, K; Gulba, DC; Lankes, W | 1 |
| Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H | 1 |
| Corno, A; Horisberger, J; Marty, B; Mueller, X; von Segesser, LK | 1 |
| Aida, H; Aoki, Y; Ohki, I; Tanaka, K | 1 |
| Tentolouris, C; Tousoulis, D; Toutouzas, P | 1 |
| Kozawa, O; Matsuno, H; Matsuo, O; Okada, K; Uematsu, T; Ueshima, S | 1 |
| Giddings, JC; Hashimoto, M; Oiwa, K; Watanabe, S; Yamamoto, J; Yamashita, T | 1 |
| Ahmad, S; Hoppensteadt, D; Hursting, MJ; Iqbal, O; Lewis, BE; Walenga, JM | 1 |
| Groulx, C; Latour, JG; Léger-Gauthier, C | 1 |
| Brajerski, W | 1 |
| Badowski, A; Orłowski, T; Witkowski, W | 1 |
| Luoma, S; Luostarinen, V; Mäkinen, KK; Rekola, M; Varrela, J | 1 |
| Raij, L; Shultz, PJ | 1 |
| Collen, D; Gold, HK; Imura, Y; Lesaffre, E; Stassen, JM; Vreys, I | 1 |
| Dawson, S; Green, FR; Humphries, SE; Lane, A | 1 |
| Allix, M; Boulu, R; Guillou, J; Plotkine, M | 1 |
| Collen, D; Imura, Y; Stassen, JM | 1 |
| Schneider, J | 1 |
| Iwamoto, M; Kumada, T; Morishita, K; Tanaka, T; Tomikawa, M; Wada, M | 1 |
| Collen, D; Fallon, JT; Gold, HK; Jang, IK; Leinbach, RC | 1 |
| Bush, LR; Connolly, TM; Mellott, MJ; York, SJ | 1 |
| Abercrombie, DM; Broeze, RJ; Buchinski, B; Salvato, KA; Stump, DC; Vovis, GF | 1 |
| Maruyama, I | 1 |
| Collen, D; Fallon, JT; Gold, HK; Jang, IK; Leinbach, RC; Ziskind, AA | 1 |
| Collins, WE; Cooper, SL; Mosher, DF; Tomasini, BR | 1 |
| Bevan, D; Chitolie, A; Cooper, DN; Grundy, C; Kakkar, V; Talbot, S | 1 |
| Breddin, HK; Haarmann, W; Krupinski, K; Markwardt, F | 1 |
| Matsui, N | 1 |
| Di Marzo, V; Erdjument, H; Lane, DA; Morris, HR; Panico, M | 1 |
| Abiko, Y; Hara, T; Iwamoto, M; Kumada, T; Ogawa, H; Tomikawa, M | 1 |
| Matsuo, T | 1 |
52 review(s) available for arginine and Blood Clot
| Article | Year |
|---|---|
Thromboprophylaxis with argatroban in critically ill patients with sepsis: a review.
Topics: Anticoagulants; Arginine; COVID-19; Critical Illness; Heparin; Heparin, Low-Molecular-Weight; Humans; Pipecolic Acids; Sepsis; Sulfonamides; Thrombocytopenia; Thrombosis; Venous Thromboembolism | 2022 |
Argatroban and Bivalirudin for Perioperative Anticoagulation in Cardiac Surgery.
Topics: Antithrombins; Arginine; Cardiac Surgical Procedures; Hirudins; Humans; Peptide Fragments; Perioperative Care; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombosis | 2018 |
[Meta-analysis of the role of Argatroban in renal replacement therapy].
Topics: Antithrombins; Arginine; Hemorrhage; Humans; Incidence; Pipecolic Acids; Renal Dialysis; Renal Insufficiency; Renal Replacement Therapy; Sulfonamides; Thrombosis | 2013 |
Anticoagulants in children and adolescents.
Topics: Adolescent; Anticoagulants; Arginine; Child; Clinical Trials as Topic; Fondaparinux; Hematology; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Sulfonamides; Thrombin; Thrombosis; Treatment Outcome; Warfarin | 2015 |
[Heparin-induced thrombocytopenia type II (HIT II) : A medical-economic view].
Topics: Arginine; Chondroitin Sulfates; Costs and Cost Analysis; Dermatan Sulfate; Germany; Hemorrhage; Heparin; Heparitin Sulfate; Hospitalization; Humans; Pipecolic Acids; Risk Factors; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2017 |
Argatroban anticoagulation in renal dysfunction: a literature analysis.
Topics: Anticoagulants; Arginine; Comorbidity; Humans; Pipecolic Acids; Prevalence; Renal Insufficiency; Sulfonamides; Thrombosis; Treatment Outcome | 2008 |
Heparin-induced thrombocytopenia: what clinicians need to know.
Topics: Anticoagulants; Arginine; Autoantibodies; Chondroitin Sulfates; Dermatan Sulfate; Drug Monitoring; Fondaparinux; Heparin; Heparitin Sulfate; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Platelet Count; Platelet Factor 4; Polysaccharides; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis; Warfarin | 2009 |
Reducing harm associated with anticoagulation: practical considerations of argatroban therapy in heparin-induced thrombocytopenia.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Dose-Response Relationship, Drug; Heparin; Humans; International Normalized Ratio; Partial Thromboplastin Time; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides; Thrombocytopenia; Thrombosis | 2009 |
Heparin-induced thrombocytopenia. A contemporary clinical approach to diagnosis and management.
Topics: Anticoagulants; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Female; Heparin; Heparitin Sulfate; Hirudins; Humans; Male; Monitoring, Physiologic; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Count; Prognosis; Randomized Controlled Trials as Topic; Recombinant Proteins; Risk Factors; Safety Management; Severity of Illness Index; Sulfonamides; Survival Rate; Thrombocytopenia; Thrombosis; Time Factors | 2009 |
Argatroban: a review of its use in the management of heparin-induced thrombocytopenia.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis | 2009 |
Pharmacology of argatroban.
Topics: Acute Coronary Syndrome; Antithrombins; Arginine; European Union; Female; Heparin; Humans; Isomerism; Japan; Male; Peptidomimetics; Pipecolic Acids; Stroke; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis; United States | 2010 |
An overview of heparin-induced thrombocytopenia.
Topics: Anticoagulants; Antithrombins; Arginine; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis; Time Factors | 2010 |
Parenteral anticoagulants: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.
Topics: Antithrombins; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Dose-Response Relationship, Drug; Evidence-Based Medicine; Fibrinolytic Agents; Fondaparinux; Heparin; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Hirudins; Humans; Infusions, Intravenous; Peptide Fragments; Pipecolic Acids; Polysaccharides; Practice Guidelines as Topic; Recombinant Proteins; Societies, Medical; Sulfonamides; Thrombin; Thrombosis; United States | 2012 |
Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome.
Topics: Acute Coronary Syndrome; Animals; Antithrombins; Arginine; Disease Models, Animal; Drug Evaluation; Heparin; Hirudins; Humans; Peptide Fragments; Percutaneous Coronary Intervention; Pipecolic Acids; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2012 |
Translational success stories: development of direct thrombin inhibitors.
Topics: Anticoagulants; Antithrombins; Arginine; Hirudin Therapy; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombosis; Translational Research, Biomedical | 2012 |
Hirudin in heparin-induced thrombocytopenia.
Topics: Anticoagulants; Antithrombins; Arginine; Blood Coagulation; Chondroitin Sulfates; Clinical Trials as Topic; Dermatan Sulfate; Drug Combinations; Fibrinolytic Agents; Heparin; Heparitin Sulfate; Hirudin Therapy; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis; Time Factors | 2002 |
An overview of the direct thrombin inhibitor argatroban.
Topics: Arginine; Humans; Pipecolic Acids; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis; Treatment Outcome | 2002 |
Argatroban in thrombotic stroke.
Topics: Animals; Anticoagulants; Arginine; Brain Ischemia; Collateral Circulation; Humans; Pipecolic Acids; Stroke; Sulfonamides; Thrombin; Thrombosis | 2002 |
The discovery of activated protein C resistance.
Topics: Activated Protein C Resistance; Arginine; Factor V; Humans; Pedigree; Point Mutation; Protein C; Risk Factors; Thrombophilia; Thrombosis | 2003 |
Treatment of heparin-induced thrombocytopenia: a critical review.
Topics: Anticoagulants; Arginine; Heparin; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Risk Assessment; Sulfonamides; Thrombocytopenia; Thrombosis | 2004 |
Argatroban therapy for antithrombin deficiency and mesenteric thrombosis: case report and review of the literature.
Topics: Adult; Anticoagulants; Antithrombins; Arginine; Humans; Male; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombosis | 2004 |
Direct thrombin inhibitors.
Topics: Anticoagulants; Arginine; Fibrinolytic Agents; Humans; Pipecolic Acids; Sulfonamides; Thrombin; Thrombosis; Warfarin | 2004 |
L-arginine and atherothrombosis.
Topics: Animals; Arginine; Arteriosclerosis; Endothelium, Vascular; Humans; Thrombosis | 2004 |
Heparin-induced thrombocytopenia: diagnosis and management.
Topics: Anticoagulants; Aortic Valve Insufficiency; Arginine; Autoantibodies; Autoimmune Diseases; Female; Fingers; Heart Valve Prosthesis Implantation; Heparin; Hirudins; Humans; Ischemia; Middle Aged; Necrosis; Pipecolic Acids; Platelet Activation; Platelet Factor 4; Postoperative Complications; Raynaud Disease; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis; Toes; Warfarin | 2004 |
Thrombin-directed inhibitors: pharmacology and clinical use.
Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Blood Coagulation; Fondaparinux; Heparin; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Sulfonamides; Thrombin; Thrombosis; Warfarin | 2005 |
Thrombin, an ideal target for pharmacological inhibition: a review of direct thrombin inhibitors.
Topics: Acute Disease; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Atrial Fibrillation; Azetidines; Benzylamines; Clinical Trials as Topic; Coronary Disease; Heparin; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Syndrome; Thrombin; Thromboembolism; Thrombosis; Venous Thrombosis | 2005 |
Transition to an oral anticoagulant in patients with heparin-induced thrombocytopenia.
Topics: Administration, Oral; Anticoagulants; Arginine; Blood Coagulation; Blood Coagulation Factors; Chondroitin Sulfates; Dermatan Sulfate; Drug Combinations; Gangrene; Heparin; Heparitin Sulfate; Hirudins; Humans; Ischemia; Leg; Necrosis; Pipecolic Acids; Recombinant Proteins; Skin; Sulfonamides; Thrombocytopenia; Thrombosis; Warfarin | 2005 |
An anesthesia provider's perspective of heparin-induced thrombocytopenia.
Topics: Anesthesia, General; Anticoagulants; Arginine; Drug Monitoring; Enzyme-Linked Immunosorbent Assay; Heparin; Hirudins; Humans; Intraoperative Care; Nurse Anesthetists; Pipecolic Acids; Platelet Count; Recombinant Proteins; Risk Factors; Sensitivity and Specificity; Severity of Illness Index; Sulfonamides; Thrombocytopenia; Thrombosis; Time Factors | 2005 |
Direct thrombin inhibitors: pharmacology and clinical relevance.
Topics: Anticoagulants; Antithrombins; Arginine; Azetidines; Benzylamines; Fibrinolytic Agents; Hirudins; Humans; Pipecolic Acids; Sulfonamides; Thrombosis | 2005 |
Clinical presentation and laboratory diagnosis of heparin-induced thrombocytopenia.
Topics: Anticoagulants; Arginine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heparin, Low-Molecular-Weight; Hirudins; Humans; Male; Pipecolic Acids; Recombinant Proteins; Risk Assessment; Severity of Illness Index; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2005 |
New trends in anticoagulant treatments.
Topics: Anticoagulants; Arginine; Azetidines; Benzylamines; Drug Design; Fibrinolytic Agents; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Prodrugs; Recombinant Proteins; Sulfonamides; Thrombosis | 2005 |
Argatroban anticoagulation in pediatric patients: a literature analysis.
Topics: Anticoagulants; Arginine; Child; Humans; Pipecolic Acids; Sulfonamides; Thrombosis | 2006 |
Uremia, atherothrombosis and malnutrition: the role of L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Humans; Kidney Failure, Chronic; Malnutrition; Nitric Oxide; Thrombosis; Uremia | 2006 |
Heparin-induced thrombocytopenia and cardiovascular diseases.
Topics: Anticoagulants; Arginine; Cardiac Surgical Procedures; Cardiovascular Diseases; Chondroitin Sulfates; Dermatan Sulfate; Diagnosis, Differential; Fondaparinux; Heparin; Heparitin Sulfate; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Factor 4; Polysaccharides; Recombinant Proteins; Sensitivity and Specificity; Sulfonamides; Thrombocytopenia; Thrombosis | 2006 |
Direct thrombin inhibition during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.
Topics: Angioplasty, Balloon, Coronary; Antithrombins; Arginine; Drug Interactions; Economics, Pharmaceutical; Fibrinolytic Agents; Hemorrhage; Heparin; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2007 |
Argatroban for anticoagulation during cardiac surgery.
Topics: Adult; Aged; Anticoagulants; Arginine; Cardiac Surgical Procedures; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Drug Monitoring; Endocarditis, Bacterial; Female; Heart Valve Prosthesis Implantation; Heparin; Humans; Intra-Aortic Balloon Pumping; Intraoperative Complications; Male; Middle Aged; Mitral Valve; Pipecolic Acids; Postoperative Complications; Retrospective Studies; Staphylococcal Infections; Subclavian Vein; Sulfonamides; Thrombosis; Venous Thrombosis; Warfarin; Whole Blood Coagulation Time | 2007 |
Heparin-induced thrombocytopenia in intensive care patients.
Topics: Anticoagulants; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Extracorporeal Circulation; Heparin; Heparitin Sulfate; Hirudins; Humans; Intensive Care Units; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis | 2007 |
Heparin-induced thrombocytopenia: treatment options and special considerations.
Topics: Anticoagulants; Antithrombins; Arginine; Heparin; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2007 |
Heparin-induced thrombocytopenia and thrombosis.
Topics: Anticoagulants; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Heparin; Heparitin Sulfate; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2007 |
Anticoagulation for acute coronary syndromes: from heparin to direct thrombin inhibitors.
Topics: Acute Disease; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Fondaparinux; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Models, Molecular; Molecular Structure; Myocardial Ischemia; Peptide Fragments; Pipecolic Acids; Platelet Activation; Polysaccharides; Recombinant Proteins; Sulfonamides; Syndrome; Thrombin; Thrombosis | 2007 |
The biological and pharmacological role of nitric oxide in platelet function.
Topics: Amino Acid Oxidoreductases; Arginine; Arteriosclerosis; Blood Platelets; Endothelium, Vascular; Enzyme Induction; Guanylate Cyclase; Hemorrhage; Hemostasis; Humans; Iron-Sulfur Proteins; Isoenzymes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation; Thrombosis; Vasodilation | 1993 |
Anticoagulation with Novastan (argatroban) in patients with heparin-induced thrombocytopenia and heparin-induced thrombocytopenia and thrombosis syndrome.
Topics: Antibodies; Antithrombins; Arginine; Heparin; Humans; Pipecolic Acids; Sulfonamides; Syndrome; Thrombocytopenia; Thrombosis | 1997 |
[Role of nitric oxic in pregnancy and pre-eclampsia].
Topics: Animals; Arginine; Blood Pressure; Endothelium, Vascular; Female; Humans; Natriuresis; Nitric Oxide; Nitroprusside; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Hematologic; Rats; Renal Circulation; Thrombosis; Vasodilation | 1997 |
[Heparin-induced thrombocytopenia].
Topics: Anticoagulants; Antithrombins; Arginine; Aspirin; Diagnosis, Differential; Fibrinolytic Agents; Heparin; Humans; Pipecolic Acids; Platelet Activation; Platelet Aggregation Inhibitors; Sulfonamides; Thrombocytopenia; Thrombosis | 1998 |
Activated protein C resistance and thrombosis: molecular mechanisms of hypercoagulable state due to FVR506Q mutation.
Topics: Activated Protein C Resistance; Arginine; Factor V; Glutamine; Humans; Point Mutation; Thrombophilia; Thrombosis | 1999 |
Heparin induced thrombocytopenia thrombosis (HIT/T) syndrome: diagnosis and treatment.
Topics: Anticoagulants; Arginine; Heparin; Hirudin Therapy; Hirudins; Humans; Pipecolic Acids; Platelet Count; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2001 |
[Direct thrombin antagonists].
Topics: Acute Disease; Angina, Unstable; Angioplasty, Balloon, Coronary; Animals; Anticoagulants; Antithrombins; Arginine; Azetidines; Benzylamines; Fibrinolytic Agents; Glycine; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Rabbits; Recombinant Proteins; Sulfonamides; Syndrome; Thrombin; Thromboembolism; Thrombosis; Time Factors | 2001 |
Anticoagulation: the present and future.
Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis | 2001 |
Alternatives to unfractionated heparin for anticoagulation in cardiopulmonary bypass.
Topics: Abciximab; Ancrod; Antibodies, Monoclonal; Anticoagulants; Arginine; Cardiopulmonary Bypass; Chondroitin Sulfates; Cross Reactions; Dermatan Sulfate; Drug Combinations; Drug Hypersensitivity; Factor Xa Inhibitors; Hemodilution; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Hirudin Therapy; Humans; Immunoglobulin Fab Fragments; Perfusion; Pipecolic Acids; Platelet Aggregation Inhibitors; Protamines; Sulfonamides; Thrombocytopenia; Thrombophilia; Thrombosis; Tirofiban; Tyrosine | 2001 |
[Plasma clotting system in neoplastic diseases].
Topics: Animals; Arginine; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Disseminated Intravascular Coagulation; Humans; Neoplasms; Platelet Aggregation; Thrombophlebitis; Thrombosis | 1976 |
The study of gene-environment interactions that influence thrombosis and fibrinolysis. Genetic variation at the loci for factor VII and plasminogen activator inhibitor-1.
Topics: Arginine; Base Sequence; Factor VII; Female; Fibrinolysis; Genetic Variation; Glutamine; Humans; Lipids; Male; Molecular Sequence Data; Plasminogen Activator Inhibitor 1; Polymorphism, Genetic; Thrombosis | 1992 |
[Artificial organs and thrombosis: hemodialysis].
Topics: Arginine; Blood Coagulation; Blood Coagulation Factors; Calcium; Gabexate; Guanidines; Heparin; Humans; Pipecolic Acids; Platelet Aggregation; Platelet Count; Renal Dialysis; Sulfonamides; Thrombosis | 1986 |
10 trial(s) available for arginine and Blood Clot
| Article | Year |
|---|---|
Clinical study of argatroban for preventing vascular thrombosis in the early period after pediatric living-related donor liver transplantation.
Topics: Adolescent; Anticoagulants; Arginine; Child; Child, Preschool; Female; Heparin; Humans; Incidence; Infant; Infant, Newborn; Liver Transplantation; Living Donors; Male; Pipecolic Acids; Platelet Aggregation Inhibitors; Postoperative Care; Postoperative Complications; Sulfonamides; Thrombosis; Treatment Outcome | 2020 |
Targeting Coagulase Activity in Staphylococcus aureus Bacteraemia: A Randomized Controlled Single-Centre Trial of Staphylothrombin Inhibition.
Topics: Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Bacteremia; Belgium; Blood Coagulation; Coagulase; Dabigatran; Enoxaparin; Feasibility Studies; Female; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Pilot Projects; Pipecolic Acids; Prospective Studies; Staphylococcal Infections; Staphylococcus aureus; Sulfonamides; Thrombin; Thrombosis; Time Factors; Treatment Outcome | 2018 |
Argatroban for elective percutaneous coronary intervention: the ARG-E04 multi-center study.
Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Blood Coagulation; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombosis | 2011 |
Rationale and design of the PREVENT-HIT study: a randomized, open-label pilot study to compare desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis.
Topics: Anticoagulants; Arginine; Female; Heparin; Hirudins; Humans; Male; Pilot Projects; Pipecolic Acids; Prospective Studies; Recombinant Proteins; Research Design; Sulfonamides; Thrombocytopenia; Thrombosis | 2010 |
A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis: PREVENT-HIT Study.
Topics: Adolescent; Adult; Aged; Anticoagulants; Arginine; Disease Progression; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Pilot Projects; Pipecolic Acids; Platelet Count; Postoperative Complications; Postoperative Period; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis; Treatment Outcome; Young Adult | 2011 |
Anticoagulant therapy with a selective thrombin inhibitor for acute cerebral infarction: usefulness of coagulation markers for evaluation of efficacy.
Topics: Acute Disease; Aged; Anticoagulants; Antithrombins; Arginine; Biomarkers; Blood Coagulation; Blood Coagulation Tests; Blood Proteins; Cerebral Infarction; Embolism; Female; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Stroke; Sulfonamides; Thrombosis; Treatment Outcome | 2002 |
A prospective comparison of three argatroban treatment regimens during hemodialysis in end-stage renal disease.
Topics: Adult; Aged; Anticoagulants; Arginine; Cross-Over Studies; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Pipecolic Acids; Prospective Studies; Renal Dialysis; Sulfonamides; Thrombosis | 2004 |
Transitioning from argatroban to warfarin in heparin-induced thrombocytopenia: an analysis of outcomes in patients with elevated international normalized ratio (INR).
Topics: Adult; Aged; Amputation, Surgical; Arginine; Cause of Death; Female; Hemorrhage; Heparin; Humans; Incidence; International Normalized Ratio; Male; Middle Aged; Pipecolic Acids; Retrospective Studies; Risk Assessment; Sulfonamides; Survival Rate; Thrombocytopenia; Thrombosis; Treatment Outcome; Warfarin | 2005 |
Thrombocytopenia following heparin flush.
Topics: Amputation, Surgical; Anticoagulants; Arginine; Catheters, Indwelling; Cause of Death; Diagnosis, Differential; Female; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Male; Middle Aged; Partial Thromboplastin Time; Patient Selection; Pipecolic Acids; Platelet Count; Prospective Studies; Recurrence; Sulfonamides; Therapeutic Irrigation; Thrombocytopenia; Thrombosis; Treatment Outcome | 2005 |
Inhibitory effect of argatroban on thrombin-antithrombin III complex after percutaneous transluminal coronary angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Antithrombin III; Antithrombins; Arginine; Biomarkers; Female; Heparin; Humans; Male; Myocardial Ischemia; Peptide Hydrolases; Pipecolic Acids; Sulfonamides; Thrombin; Thrombosis | 1995 |
197 other study(ies) available for arginine and Blood Clot
| Article | Year |
|---|---|
A journey through anticoagulant therapies in the treatment of left ventricular thrombus in post-COVID-19 heparin-induced thrombocytopenia: a case report.
Topics: Acenocoumarol; Anticoagulants; Arginine; COVID-19; COVID-19 Drug Treatment; Heparin; Hirudins; Humans; Male; Middle Aged; Peptide Fragments; Percutaneous Coronary Intervention; Pipecolic Acids; Recombinant Proteins; SARS-CoV-2; Sulfonamides; Thrombocytopenia; Thrombosis | 2022 |
Impact of poly-arginine peptides R18D and R18 on alteplase and tenecteplase thrombolysis in vitro, and neuroprotective stability to proteolysis.
Topics: Arginine; Brain Ischemia; Fibrinolytic Agents; Humans; Peptides; Proteolysis; Stroke; Tenecteplase; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 2022 |
A Fibrinogen-Mimicking, Activated-Platelet-Sensitive Nanocoacervate Enhances Thrombus Targeting and Penetration of Tissue Plasminogen Activator for Effective Thrombolytic Therapy.
Topics: Animals; Arginine; Aspartic Acid; Chitosan; Fibrinogen; Fibrinolytic Agents; Glycine; Hemorrhage; Hemostatics; Mice; Oligopeptides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 2022 |
Asymmetric Dimethylarginine Is a Marker of Endothelial Dysfunction in Thrombotic Antiphospholipid Syndrome Patients.
Topics: Antiphospholipid Syndrome; Arginine; Biomarkers; C-Reactive Protein; Dilatation, Pathologic; Endothelium, Vascular; Humans; Nitroglycerin; Thrombosis; Vasodilation | 2022 |
Argatroban to achieve therapeutic anticoagulation in two patients with acute thrombosis and heparin resistance.
Topics: Acute Disease; Adult; Anticoagulants; Arginine; Drug Resistance; Female; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombosis | 2019 |
Myocardial Infarction with Limb Arterial and Venous Thrombosis in a Patient with Enoxaparin-Induced Thrombocytopenia.
Topics: Aged; Antithrombins; Arginine; Enoxaparin; Factor Xa Inhibitors; Female; Humans; Pipecolic Acids; Pyrazoles; Pyridones; ST Elevation Myocardial Infarction; Sulfonamides; Thrombocytopenia; Thrombosis | 2020 |
Thrombocytopenia and Thromboses in Myocardial Infarction Associated with Eptifibatide-Dependent Activating Antiplatelet Antibodies.
Topics: Antigens, Human Platelet; Arginine; Aspirin; Autoantibodies; Combined Modality Therapy; Coronary Thrombosis; Drug Substitution; Drug Therapy, Combination; Eptifibatide; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Transfusion; Purpura, Thrombocytopenic, Idiopathic; Shock, Cardiogenic; ST Elevation Myocardial Infarction; Stents; Sulfonamides; Thrombectomy; Thrombolytic Therapy; Thrombosis; Ticagrelor; Warfarin | 2020 |
Utilization and Outcomes of Children Treated with Direct Thrombin Inhibitors on Paracorporeal Ventricular Assist Device Support.
Topics: Adolescent; Antithrombins; Arginine; Child; Child, Preschool; Female; Heart-Assist Devices; Hemorrhage; Hirudins; Humans; Infant; Male; North America; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Stroke; Sulfonamides; Thrombosis; Treatment Outcome | 2020 |
Argatroban for therapeutic anticoagulation for heparin resistance associated with Covid-19 infection.
Topics: Adult; Anticoagulants; Arginine; Catheter Obstruction; COVID-19; Drug Resistance; Drug Substitution; Fibrin Fibrinogen Degradation Products; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Pulmonary Embolism; Respiration, Artificial; SARS-CoV-2; Sulfonamides; Thrombosis; Tomography, X-Ray Computed; Treatment Outcome | 2021 |
Aortic Arch Thrombus and Pulmonary Embolism in a COVID-19 Patient.
Topics: Anticoagulants; Antithrombins; Aorta, Thoracic; Arginine; Biomarkers; COVID-19; Female; Heparin; Humans; Middle Aged; Pipecolic Acids; Pneumonia, Viral; Pulmonary Embolism; SARS-CoV-2; Sulfonamides; Thrombosis | 2021 |
The Effects of the Combined Argatroban/Nitric Oxide-Releasing Polymer on Platelet Microparticle-Induced Thrombogenicity in Coated Extracorporeal Circuits.
Topics: Animals; Antithrombins; Arginine; Blood Platelets; Cell-Derived Microparticles; Extracorporeal Circulation; Nitric Oxide; Pipecolic Acids; Platelet Activation; Polymers; Rabbits; Sulfonamides; Thrombosis | 2021 |
Expansion of Myeloid Derived Suppressor Cells Contributes to Platelet Activation by L-Arginine Deprivation during SARS-CoV-2 Infection.
Topics: Adult; Aged; Aged, 80 and over; Arginine; COVID-19; Female; Humans; Male; Middle Aged; Myeloid-Derived Suppressor Cells; Platelet Activation; Thrombosis; Young Adult | 2021 |
Anticoagulation in children: Making the most of little patients and little evidence.
Topics: Anticoagulants; Arginine; Blood Coagulation; Child; Drug Monitoring; Fondaparinux; Heparin; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Sulfonamides; Thrombosis; Venous Thromboembolism; Warfarin | 2017 |
The Use of Eptifibatide Alone or in Combination With Heparin or Argatroban for Suspected Thrombosis in Patients With Left Ventricular Assist Devices.
Topics: Adult; Aged; Anticoagulants; Arginine; Eptifibatide; Female; Heart Failure; Heart-Assist Devices; Hemolysis; Heparin; Humans; Male; Middle Aged; Peptides; Pipecolic Acids; Platelet Aggregation Inhibitors; Retrospective Studies; Sulfonamides; Thrombosis; Warfarin; Young Adult | 2017 |
Argatroban for Heparin-Induced Thrombocytopenia during Venovenous Extracorporeal Membrane Oxygenation with Continuous Venovenous Hemofiltration.
Topics: Adult; Anticoagulants; Antithrombins; Arginine; Dose-Response Relationship, Drug; Extracorporeal Membrane Oxygenation; Hemofiltration; Heparin; Humans; Male; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2017 |
Idiopathic catastrophic thrombosis with happy ending.
Topics: Anticoagulants; Antithrombins; Arginine; Awareness; Blood Coagulation Tests; Coronary Artery Bypass; Heparin; Humans; Male; Middle Aged; Phenprocoumon; Pipecolic Acids; Platelet Aggregation Inhibitors; ST Elevation Myocardial Infarction; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome; Ultrasonography; Venous Thrombosis | 2017 |
Cerebral Venous Sinus Thrombosis Due to Low-molecular-weight Heparin-induced Thrombocytopenia.
Topics: Anticoagulants; Arginine; Female; Heparin, Low-Molecular-Weight; Humans; Middle Aged; Pipecolic Acids; Platelet Count; Sulfonamides; Thrombocytopenia; Thrombosis; Venous Thrombosis | 2017 |
Pre-clinical model of severe glutathione peroxidase-3 deficiency and chronic kidney disease results in coronary artery thrombosis and depressed left ventricular function.
Topics: Animals; Arginine; Disease Models, Animal; Glutathione Peroxidase; Heart Diseases; Mice; Mice, Knockout; Platelet Aggregation; Reactive Oxygen Species; Renal Insufficiency, Chronic; Thrombosis; Ventricular Dysfunction, Left | 2018 |
Synthesis and biocompatibility of an argatroban-modified polysulfone membrane that directly inhibits thrombosis.
Topics: Adsorption; Adult; Anticoagulants; Arginine; Blood Coagulation; Blood Coagulation Tests; Humans; Hydrophobic and Hydrophilic Interactions; Male; Materials Testing; Membranes, Artificial; Pipecolic Acids; Platelet Adhesiveness; Polymers; Renal Dialysis; Sulfonamides; Sulfones; Thrombosis | 2018 |
An infrequent complication of a not so infrequent disease. Hit by HIT.
Topics: Acute Coronary Syndrome; Aged; Anticoagulants; Antithrombins; Aortic Valve; Arginine; Drug Substitution; Echocardiography, Transesophageal; Electrocardiography; Extracorporeal Membrane Oxygenation; Fatal Outcome; Heart Arrest; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation; Heparin; Humans; Male; Pipecolic Acids; Sulfonamides; Thrombectomy; Thrombocytopenia; Thrombosis; Treatment Outcome | 2019 |
Reversible Auricular Necrosis Secondary to Systemic Thrombosis.
Topics: Anticoagulants; Antiphospholipid Syndrome; Arginine; Ear Auricle; Ear Diseases; Female; Heparin; Humans; Necrosis; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2018 |
High-dose intravenous immunoglobulin to treat spontaneous heparin-induced thrombocytopenia syndrome.
Topics: Anticoagulants; Arginine; Arthroplasty, Replacement, Knee; Female; Fondaparinux; Gastrointestinal Hemorrhage; Heparin; Humans; Immunoglobulins, Intravenous; Middle Aged; Pipecolic Acids; Platelet Activation; Platelet Count; Serotonin; Sulfonamides; Thrombocytopenia; Thrombosis; Venous Thromboembolism | 2019 |
Intravenous warfarin and heparin-induced thrombocytopenia: making the diagnosis, management, modern monitoring, and multidisciplinary care.
Topics: Aged; Anticoagulants; Antithrombins; Arginine; Cardiac Surgical Procedures; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Male; Pipecolic Acids; Pulmonary Embolism; Sulfonamides; Thrombocytopenia; Thrombosis; Warfarin | 2014 |
A novel fibrin(ogen)olytic trypsin-like protease from Chinese oak silkworm (Antheraea pernyi): purification and characterization.
Topics: Amino Acid Sequence; Animals; Arginine; China; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Esterases; Fibrin; Fibrinogen; Fibrinolysis; Insect Proteins; Kinetics; Mice; Molecular Sequence Data; Moths; Peptide Hydrolases; Phylogeny; Sequence Analysis, DNA; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Substrate Specificity; Thrombosis; Trypsin | 2014 |
Thrombosis of biatrial appendages due to heparin-induced thrombocytopenia.
Topics: Aged, 80 and over; Antibodies; Anticoagulants; Arginine; Arterial Occlusive Diseases; Atrial Appendage; Atrial Fibrillation; Biomarkers; Coronary Artery Bypass; Drug Administration Schedule; Drug Substitution; Female; Heart Diseases; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombectomy; Thrombocytopenia; Thrombosis; Tomography, X-Ray Computed | 2013 |
Mannose-binding lectin promotes local microvascular thrombosis after transient brain ischemia in mice.
Topics: Animals; Antithrombins; Arginine; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Fibrinogen; Infarction, Middle Cerebral Artery; Magnetic Resonance Imaging; Male; Mannose-Binding Lectin; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcirculation; Pipecolic Acids; Reperfusion Injury; Sulfonamides; Thrombosis | 2014 |
The effect of a polyurethane coating incorporating both a thrombin inhibitor and nitric oxide on hemocompatibility in extracorporeal circulation.
Topics: Animals; Antithrombins; Arginine; Blood Coagulation; Blood Platelets; Coated Materials, Biocompatible; Extracorporeal Circulation; Isocyanates; Nitric Oxide; Pipecolic Acids; Platelet Activation; Platelet Function Tests; Polyethylene Glycols; Polymers; Polyurethanes; Rabbits; Sulfonamides; Thrombin; Thrombosis | 2014 |
Progressive, Fatal Thrombosis Associated With Heparin-Induced Thrombocytopenia After Cardiac Surgery Despite "Therapeutic" Anticoagulation With Argatroban: Potential Role for PTT and ACT Confounding.
Topics: Adult; Antithrombins; Aortic Valve Stenosis; Arginine; Fatal Outcome; Fibrinolytic Agents; Heart Valve Prosthesis Implantation; Heparin; Humans; Infusions, Intravenous; Male; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis; Whole Blood Coagulation Time | 2015 |
Management of intraoperative free flap arterial thrombosis with argatroban in the heparin-allergic patient.
Topics: Anticoagulants; Antithrombins; Arginine; Drug Hypersensitivity; Female; Free Tissue Flaps; Heparin; Humans; Intraoperative Complications; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombosis | 2014 |
Implantation of left ventricular assist devices under extracorporeal life support in patients with heparin-induced thrombocytopenia.
Topics: Acute Disease; Adult; Aged; Anticoagulants; Arginine; Cohort Studies; Extracorporeal Circulation; Female; Heart Failure; Heart-Assist Devices; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Prosthesis Implantation; Sulfonamides; Thrombocytopenia; Thrombosis | 2015 |
Minimal Prolongation of Prothrombin Time with Extended Exposure to Argatroban.
Topics: Anticoagulants; Antithrombins; Arginine; Carcinoma, Squamous Cell; Drug Substitution; Female; Heparin; Humans; International Normalized Ratio; Mandibular Neoplasms; Middle Aged; Mouth Mucosa; Pipecolic Acids; Prothrombin Time; Sulfonamides; Syndrome; Thrombocytopenia; Thrombosis; Treatment Failure; Warfarin | 2015 |
[Monitoring of 4 patients with heparin-induced thrombocytopenia after complex congenital heart surgery].
Topics: Anticoagulants; Arginine; Cardiac Surgical Procedures; Heparin; Humans; Incidence; Infant; Pipecolic Acids; Platelet Count; Prognosis; Sulfonamides; Thrombocytopenia; Thrombosis | 2015 |
Asymmetric dimethylarginine predicts left atrial appendage thrombus in patients with non-valvular atrial fibrillation.
Topics: Aged; Arginine; Atrial Appendage; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Nitric Oxide; Thrombosis | 2015 |
Reversal strategies for non-vitamin K antagonist oral anticoagulants: a critical appraisal of available evidence and recommendations for clinical management-a joint position paper of the European Society of Cardiology Working Group on Cardiovascular Pharm
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Consensus; Dabigatran; Evidence-Based Medicine; Factor Xa; Forecasting; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Risk Factors; Thrombosis; Vitamin K | 2017 |
Heparin-Induced-Thrombocytopenia Causing Massive Aortic Thrombosis after Ascending Aortic Replacement for Type A Acute Aortic Dissection.
Topics: Acute Disease; Aged; Anticoagulants; Aortic Aneurysm; Aortic Diseases; Aortic Dissection; Aortography; Arginine; Blood Vessel Prosthesis Implantation; Computed Tomography Angiography; Drug Substitution; Emergencies; Fatal Outcome; Female; Gastrointestinal Hemorrhage; Heparin; Humans; Mesenteric Ischemia; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis; Time Factors; Treatment Outcome | 2016 |
Endothelin 1, ADMA and SDMA in pregnancies with obstetric and thrombotic antiphospholipid syndrome.
Topics: Adult; Antiphospholipid Syndrome; Arginine; Chronic Disease; Endothelin-1; Endothelium, Vascular; Female; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Prognosis; Thrombosis; Young Adult | 2016 |
[Effect of asymmetrical dimethylarginine for predicting pro-thrombotic risk in atrial fibrillation].
Topics: Arginine; Atrial Fibrillation; Cardiovascular Diseases; Heart Atria; Humans; Stereoisomerism; Thrombosis | 2016 |
Histones link inflammation and thrombosis through the induction of Weibel-Palade body exocytosis.
Topics: Animals; Arginine; Caspases; DNA; Endothelial Cells; Exocytosis; Histones; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lysine; Mice; Mice, Inbred C57BL; Platelet Adhesiveness; Thrombosis; Weibel-Palade Bodies | 2016 |
Rapid and durable response to intravenous immunoglobulin in delayed heparin-induced thrombocytopenia: a case report.
Topics: Arginine; Cardiac Surgical Procedures; Heparin; Hirudins; Humans; Immunoglobulins, Intravenous; Male; Middle Aged; Peptide Fragments; Pipecolic Acids; Postoperative Complications; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2017 |
Heparin-induced thrombocytopenia with aortoiliac thrombosis treated with argatroban.
Topics: Anticoagulants; Antithrombins; Aortic Diseases; Arginine; Heparin; Humans; Iliac Artery; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2017 |
Complete salvage of impending free flap failure in heparin induced thrombocytopenia by emergent institution of therapy with argatroban.
Topics: Anastomosis, Surgical; Anticoagulants; Arginine; Carcinoma, Squamous Cell; Female; Graft Rejection; Heparin; Humans; Middle Aged; Mouth Neoplasms; Pipecolic Acids; Reoperation; Salvage Therapy; Sulfonamides; Surgical Flaps; Thrombocytopenia; Thrombosis; Veins | 2008 |
Treatment of intracardiac thrombi with argatroban.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arginine; Female; Heart Diseases; Humans; Male; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides; Thrombosis; Treatment Outcome; Whole Blood Coagulation Time | 2008 |
Variance of DDAH/PRMT/ADMA pathway in atrial fibrillation dogs.
Topics: Amidohydrolases; Animals; Arginine; Atrial Fibrillation; Disease Models, Animal; Dogs; Down-Regulation; Endothelium; Female; Male; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein-Arginine N-Methyltransferases; Thrombosis; Up-Regulation | 2008 |
Dosing patterns and outcomes in African American, Asian, and Hispanic patients with heparin-induced thrombocytopenia treated with argatroban.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arginine; Asian; Black or African American; Female; Fibrinolytic Agents; Heparin; Hispanic or Latino; Humans; Male; Middle Aged; Pipecolic Acids; Prospective Studies; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thrombosis | 2009 |
Risk factors for major bleeding in patients with heparin-induced thrombocytopenia treated with argatroban: a retrospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Arginine; Blood Coagulation; Drug Monitoring; Female; Hemorrhage; Heparin; Humans; Lung Diseases; Male; Middle Aged; Odds Ratio; Partial Thromboplastin Time; Pipecolic Acids; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonamides; Thrombocytopenia; Thrombosis; Young Adult | 2008 |
Influence of antithrombin and argatroban on disseminated intravascular coagulation parameters in a patient with septic shock.
Topics: Aged; Anticoagulants; Antithrombins; Arginine; Blood Coagulation; Female; Humans; Pipecolic Acids; Shock, Septic; Sulfonamides; Thrombosis | 2009 |
Heparin-induced thrombocytopenia in two patients undergoing abdominal aortic aneurysm surgery.
Topics: Aged; Anticoagulants; Aortic Aneurysm, Abdominal; Arginine; Autoantibodies; Disseminated Intravascular Coagulation; Heparin; Humans; Male; Mesenteric Arteries; Pipecolic Acids; Platelet Factor 4; Postoperative Complications; Sulfonamides; Thrombocytopenia; Thrombosis | 2010 |
A report of outcomes after orthotopic liver transplant with allografts from heparin antibody-positive donors.
Topics: Algorithms; Antibodies; Anticoagulants; Arginine; Clinical Protocols; Female; Heparin; Humans; Liver Transplantation; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis; Tissue Donors; Transplantation, Homologous; Young Adult | 2009 |
Thrombin generation by intimal tissue factor contributes to thrombus formation on macrophage-rich neointima but not normal intima of hyperlipidemic rabbits.
Topics: Angioplasty, Balloon; Animals; Arginine; Femoral Artery; Humans; Hyperlipidemias; Lipoproteins; Macrophages; Male; Pipecolic Acids; Rabbits; Sulfonamides; Thrombin; Thromboplastin; Thrombosis; Tunica Intima | 2009 |
Argatroban and bivalirudin compared to unfractionated heparin in preventing thrombus formation on mechanical heart valves. Results of an in-vitro study.
Topics: Anticoagulants; Arginine; Diagnostic Techniques, Cardiovascular; Drug Therapy, Combination; Feasibility Studies; Heart Diseases; Heart-Assist Devices; Heparin; Hirudins; Humans; In Vitro Techniques; Infusion Pumps; Male; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis | 2009 |
Impact of renal function on argatroban therapy during percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Clinical Trials as Topic; Female; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Renal Insufficiency; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2010 |
Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activity.
Topics: Arginine; Aspirin; Carboxylic Acids; Catalytic Domain; Chemistry, Pharmaceutical; Drug Design; Esters; Humans; Platelet Activation; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Serine; Thrombosis; Tyrosine | 2009 |
Argatroban dosage requirements and outcomes in intensive care versus non-intensive care patients.
Topics: Aged; Aged, 80 and over; Anticoagulants; Arginine; Critical Care; Dose-Response Relationship, Drug; Female; Heparin; Humans; Intensive Care Units; Male; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2009 |
Heparin-induced thrombocytopenia with multiple organized thrombi accompanied by unusual cholesterin deposition: autopsy case after long-term follow up.
Topics: Aged; Anticoagulants; Arginine; Embolism, Cholesterol; Fatal Outcome; Heparin; Humans; Male; Pipecolic Acids; Platelet Count; Sulfonamides; Thrombocytopenia; Thrombosis; Warfarin | 2009 |
[Heparin-induced thrombocytopenia type II with thrombosis in an intensive care patient: therapy management using the direct thrombin inhibitor argatroban].
Topics: Aged; Anticoagulants; Aortic Aneurysm, Abdominal; Aortic Rupture; Arginine; Exanthema; Heparin; Humans; Male; Partial Thromboplastin Time; Pipecolic Acids; Platelet Count; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis | 2009 |
Prolonged elevation of plasma argatroban in a cardiac transplant patient with a suspected history of heparin-induced thrombocytopenia with thrombosis.
Topics: Aged; Arginine; Blood Coagulation Disorders; Cardiopulmonary Bypass; Child; Heart Transplantation; Heparin; Humans; Infusions, Intravenous; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides; Thrombocytopenia; Thrombosis | 2010 |
A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease.
Topics: Aged; Amidohydrolases; Arginine; Asian People; Binding Sites; Biomarkers; Case-Control Studies; Cells, Cultured; Chi-Square Distribution; China; Coronary Artery Disease; DNA Mutational Analysis; DNA-Binding Proteins; Female; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Mutagenesis, Insertional; Odds Ratio; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Assessment; Risk Factors; Sequence Deletion; Stroke; Thrombosis; Transcription Factor MTF-1; Transcription Factors; Transcriptional Activation; Transfection | 2010 |
The direct thrombin inhibitor argatroban effectively prevents cardiac catheter thrombosis in vitro.
Topics: Anticoagulants; Antithrombin III; Arginine; Blood Coagulation; Blood Platelets; Cardiac Catheterization; Enoxaparin; Factor Xa; Factor Xa Inhibitors; Fibrin; Heparin; Humans; Male; Peptide Hydrolases; Pipecolic Acids; Stress, Mechanical; Sulfonamides; Thrombin; Thrombosis; Time Factors | 2010 |
Treatment with argatroban in one haemodialysed patient with a heparin-induced thrombocytopenia and thrombotic complications.
Topics: Aged, 80 and over; Arginine; Female; Heparin; Humans; Pipecolic Acids; Platelet Aggregation Inhibitors; Renal Dialysis; Sulfonamides; Thrombocytopenia; Thrombosis | 2010 |
The direct thrombin inhibitors (argatroban, bivalirudin and lepirudin) and the indirect Xa-inhibitor (danaparoid) increase fibrin network porosity and thus facilitate fibrinolysis.
Topics: Antithrombins; Arginine; Chondroitin Sulfates; Chromatography, Gel; Dermatan Sulfate; Factor VIII; Factor Xa Inhibitors; Fibrin; Fibrinolysis; Heparinoids; Heparitin Sulfate; Hirudins; Humans; In Vitro Techniques; Microscopy, Confocal; Peptide Fragments; Pipecolic Acids; Plasma; Porosity; Protein Multimerization; Recombinant Proteins; Sulfonamides; Thrombosis; Tissue Plasminogen Activator | 2010 |
Down but not out: candidate gene-based studies still have value in a world dominated by whole genome approaches.
Topics: Amidohydrolases; Arginine; Asian People; Biomarkers; China; Coronary Artery Disease; Evidence-Based Medicine; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors; Stroke; Thrombosis | 2010 |
Safety and efficacy of the argatroban therapy during the early post-cardiac surgery period.
Topics: Aged; Aged, 80 and over; Arginine; Cardiac Surgical Procedures; Drug-Related Side Effects and Adverse Reactions; Female; Hemorrhage; Hospital Mortality; Humans; Male; Middle Aged; Pipecolic Acids; Postoperative Care; Postoperative Complications; Retrospective Studies; Sulfonamides; Thrombin; Thrombosis; Treatment Outcome | 2010 |
Argatroban therapy in pediatric patients requiring nonheparin anticoagulation: an open-label, safety, efficacy, and pharmacokinetic study.
Topics: Anticoagulants; Arginine; Child; Child, Preschool; Female; Hemorrhage; Heparin; Humans; Infant; Liver Function Tests; Male; Pipecolic Acids; Platelet Aggregation Inhibitors; Prospective Studies; Sulfonamides; Survival Rate; Thrombocytopenia; Thrombosis; Tissue Distribution; Treatment Outcome | 2011 |
Combined argatroban and anti-oxidative agents prevents increased vascular contractility to thrombin and other ligands after subarachnoid haemorrhage.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Drug Therapy, Combination; Male; Pipecolic Acids; Rabbits; Receptor, PAR-1; Signal Transduction; Subarachnoid Hemorrhage; Sulfonamides; Thiobarbituric Acid Reactive Substances; Thrombin; Thrombosis; Vasoconstriction | 2012 |
Immunosuppressants accelerate microvascular thrombus formation in vivo: role of endothelial cell activation.
Topics: Animals; Arginine; Endothelium, Vascular; Immunohistochemistry; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Microvessels; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; P-Selectin; Reperfusion Injury; Thrombosis; Vascular Cell Adhesion Molecule-1 | 2012 |
Recognition of heparin-induced thrombocytopenia and initiation of argatroban therapy after cardiothoracic surgery in the intensive care unit.
Topics: Antibodies; Anticoagulants; Arginine; Cardiac Surgical Procedures; Drug Substitution; Georgia; Hemorrhage; Heparin; Humans; Intensive Care Units; Pipecolic Acids; Platelet Factor 4; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonamides; Thoracic Surgical Procedures; Thrombocytopenia; Thrombosis; Time Factors; Treatment Outcome | 2012 |
High-dose argatroban for treatment of heparin-induced thrombocytopenia with thrombosis: a case report and review of laboratory considerations.
Topics: Anticoagulants; Arginine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Heparin; Humans; International Normalized Ratio; Middle Aged; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides; Thrombocytopenia; Thrombosis | 2012 |
A case of acute coronary artery occlusion associated with very rapid onset heparin-induced thrombosis without thrombocytopenia.
Topics: Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Aspirin; Autoantibodies; Cilostazol; Clopidogrel; Coronary Angiography; Coronary Occlusion; Drug Therapy, Combination; Female; Heart Failure; Heparin; Humans; Pipecolic Acids; Platelet Count; Platelet Factor 4; Stents; Sulfonamides; Tetrazoles; Thrombosis; Ticlopidine; Time Factors | 2012 |
Effect of atrial fibrillation on atrial thrombogenesis in humans: impact of rate and rhythm.
Topics: Aged; Antithrombin III; Arginine; Atrial Fibrillation; Catheter Ablation; CD40 Ligand; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Heart Atria; Heart Rate; Humans; Male; Middle Aged; P-Selectin; Peptide Hydrolases; Platelet Activation; Risk Assessment; Risk Factors; Statistics as Topic; Stroke; Thrombosis | 2013 |
Argatroban anticoagulation during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.
Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Atherectomy, Coronary; Female; Heparin; Humans; Male; Pipecolic Acids; Stents; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2002 |
Argatroban for percutaneous coronary interventions: hit or miss?
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2002 |
Endothelial dysfunction after arterial thrombosis is ameliorated by L-arginine in combination with thrombolysis.
Topics: Animals; Arginine; Endothelium, Vascular; Female; Nitric Oxide; Swine; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 2003 |
Deletion of P1 arginine in a novel antithrombin variant (antithrombin London) abolishes inhibitory activity but enhances heparin affinity and is associated with early onset thrombosis.
Topics: Age of Onset; Antithrombin Proteins; Antithrombins; Arginine; Binding, Competitive; Blood Coagulation; Chromatography, Affinity; Chromatography, Liquid; Electrophoresis, Polyacrylamide Gel; Factor Xa Inhibitors; Family Health; Female; Gene Deletion; Heparin; Heparitin Sulfate; Heterozygote; Humans; Kinetics; Male; Models, Biological; Pedigree; Protein Binding; Proteins; Thrombin; Thrombosis; Time Factors | 2003 |
Effects of argatroban and heparin on thrombus formation and tissue plasminogen activator-induced thrombolysis in a microvascular thrombosis model.
Topics: Animals; Arginine; Cricetinae; Disease Models, Animal; Drug Interactions; Fibrinolytic Agents; Heparin; Mesocricetus; Microcirculation; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombolytic Therapy; Thrombosis; Time Factors; Tissue Plasminogen Activator | 2003 |
Suppression of argatroban-induced endogenous thrombolysis by PKSI-527, and antibodies to TPA and UPA, evaluated in a rat arterial thrombolysis model.
Topics: Animals; Antibodies; Arginine; Drug Antagonism; Fibrinolysin; Fibrinolysis; Fibrinolytic Agents; Kallikreins; Male; Mesenteric Arteries; Phenylalanine; Pipecolic Acids; Plasma Kallikrein; Rats; Rats, Wistar; Sulfonamides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator; Tranexamic Acid; Urokinase-Type Plasminogen Activator | 2003 |
Anti-thrombotic activity of PDR, a newly synthesized L-Arg derivative, on three thrombosis models in rats.
Topics: Adenosine Diphosphate; Animals; Arginine; Arteriovenous Shunt, Surgical; Autacoids; Chlorides; Collagen; Electric Stimulation; Ferric Compounds; Fibrinolytic Agents; Male; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombin; Thrombosis | 2003 |
Decreased argatroban clearance unaffected by hemodialysis in anasarca.
Topics: Acute Kidney Injury; Arginine; Edema; Female; Humans; Middle Aged; Pipecolic Acids; Renal Dialysis; Sulfonamides; Thrombin; Thrombosis | 2003 |
Antithrombotic properties of a direct thrombin inhibitor with a prolonged half-life and AT-mediated factor Xa inhibitory activity.
Topics: Animals; Antithrombin III; Arginine; Blood Coagulation Tests; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Factor Xa Inhibitors; Fibrinolytic Agents; Fondaparinux; Half-Life; Hemorrhage; Heparin; Male; Molecular Structure; Oligosaccharides; Pipecolic Acids; Polysaccharides; Rabbits; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombolytic Therapy; Thrombosis | 2003 |
INHIBITION OF ADP-INDUCED PLATELET AGGREGATION BY SUBSTITUTED AMINO-ACIDS.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Alanine; Alkylation; Amino Acids; Aminocaproates; Aminocaproic Acid; Arginine; Blood Platelets; Butyrates; Glutamine; Glycine; Guanidines; Leucine; Pharmacology; Phenylalanine; Platelet Aggregation; Proline; Research; Thrombosis; Tyrosine | 1964 |
Treatment options for heparin-induced thrombocytopenia.
Topics: Antithrombins; Arginine; Heparin; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis; United States | 2003 |
Argatroban use during pediatric interventional cardiac catheterization.
Topics: Antithrombins; Arginine; Cardiac Catheterization; Child; Embolization, Therapeutic; Fibrinolytic Agents; Heart Diseases; Heparin; Humans; Male; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2004 |
Heparinless cardiopulmonary bypass with argatroban in dogs.
Topics: Animals; Anticoagulants; Arginine; Blood Coagulation; Cardiopulmonary Bypass; Dogs; Dose-Response Relationship, Drug; Fibrinolysis; Heparin; Intraoperative Care; Kidney; Pipecolic Acids; Postoperative Complications; Sulfonamides; Thrombosis | 2004 |
Ability of anti-glycoprotein IIb/IIIa agents to dissolve platelet thrombi formed on a collagen surface under blood flow conditions.
Topics: Abciximab; Adult; Antibodies, Monoclonal; Anticoagulants; Arginine; Blood Platelets; Collagen; Eptifibatide; Fibrinolytic Agents; Hemorheology; Humans; Immunoglobulin Fab Fragments; In Vitro Techniques; Peptides; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Sulfonamides; Thrombosis; Tirofiban; Tyrosine | 2004 |
Heparin-induced thrombocytopenia and thrombosis in a patient with polycythemia vera.
Topics: Aged; Arginine; Female; Follow-Up Studies; Heparin; Humans; Japan; Pipecolic Acids; Polycythemia Vera; Pulmonary Embolism; Risk Assessment; Severity of Illness Index; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2004 |
Argatroban as an alternative to heparin in extracorporeal membrane oxygenation circuits.
Topics: Arginine; Biomarkers; Blood Coagulation Tests; Equipment Failure; Extracorporeal Membrane Oxygenation; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombelastography; Thrombin; Thrombosis | 2004 |
IgG antibodies that recognize epitope Gly40-Arg43 in domain I of beta 2-glycoprotein I cause LAC, and their presence correlates strongly with thrombosis.
Topics: Adult; Antibody Specificity; Arginine; beta 2-Glycoprotein I; Binding Sites, Antibody; Enzyme-Linked Immunosorbent Assay; Epitopes; Female; Glycine; Glycoproteins; Humans; Immunoglobulin G; Lupus Coagulation Inhibitor; Male; Odds Ratio; Protein Structure, Tertiary; Thrombosis | 2005 |
Severe argatroban-induced coagulopathy in a patient with a history of heparin-induced thrombocytopenia.
Topics: Aged; Aged, 80 and over; Anticoagulants; Aortic Valve; Aortic Valve Stenosis; Arginine; Blood Coagulation Disorders; Heart Valve Prosthesis Implantation; Heparin; Humans; Male; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2004 |
No increase in rejection or graft loss in kidney transplant recipients with thrombophilia treated with anticoagulation and triple immunosuppression.
Topics: Anticoagulants; Arginine; Creatinine; Drug Therapy, Combination; Factor V; Female; Graft Rejection; Graft Survival; Heparin; Histocompatibility Testing; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mutation; Pipecolic Acids; Sulfonamides; Thrombophilia; Thrombosis | 2005 |
Mechanism of antithrombotic effect of heparin and antithrombin in balloon-injured arteries.
Topics: Angiography; Animals; Antithrombins; Arginine; Arteries; Catheterization; Dogs; Fibrinogen; Fibrinolytic Agents; Heparin; Iliac Artery; Microscopy, Fluorescence; Partial Thromboplastin Time; Pipecolic Acids; Prothrombin Time; Sulfonamides; Thrombosis | 2005 |
Direct thrombin inhibitors.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Benzimidazoles; Blood Coagulation; Dabigatran; Heart Diseases; Heparin; Humans; Pipecolic Acids; Prodrugs; Pyridines; Sulfonamides; Thrombin; Thromboembolism; Thrombosis; Venous Thrombosis | 2005 |
Direct thrombin inhibitors are not equally effective in vivo against arterial thrombosis: in vivo evaluation of DuP714 and argatroban in a porcine angioplasty model and comparison to r-hirudin.
Topics: Angioplasty, Balloon; Animals; Anticoagulants; Arginine; Boron Compounds; Drug Evaluation, Preclinical; Hirudins; Oligopeptides; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Swine; Thrombin; Thrombosis | 2005 |
Cardiopulmonary bypass using argatroban as an anticoagulant for a 6.0-kg pediatric patient.
Topics: Anticoagulants; Arginine; Cardiopulmonary Bypass; Extracorporeal Membrane Oxygenation; Heart Defects, Congenital; Humans; Infant; Pipecolic Acids; Sulfonamides; Thrombosis | 2005 |
[Argatroban].
Topics: Anticoagulants; Arginine; Drug Monitoring; Humans; Pipecolic Acids; Sulfonamides; Thrombosis | 2006 |
Argatroban dosing of patients with heparin-induced thrombocytopenia and an elevated aPTT due to antiphospholipid antibody syndrome.
Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Arginine; Female; Fondaparinux; Heparin; Humans; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Polysaccharides; Sulfonamides; Thrombocytopenia; Thrombosis | 2006 |
Inhibitors of blood coagulation factors Xa and IIa synergize to reduce thrombus weight and thrombin generation in vivo and in vitro.
Topics: Animals; Arginine; Bleeding Time; Factor Xa Inhibitors; Fibrinolytic Agents; Humans; In Vitro Techniques; Partial Thromboplastin Time; Pipecolic Acids; Piperidines; Platelet Aggregation Inhibitors; Prothrombin; Rabbits; Sulfonamides; Thrombin; Thrombosis | 2006 |
In vivo antithrombotic synergy of oral heparin and arginine: endothelial thromboresistance without changes in coagulation parameters.
Topics: Animals; Arginine; Blood Coagulation; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Fibrinolytic Agents; Glycosaminoglycans; Heparin; Rats; Thrombosis | 2006 |
Argatroban therapy in heparin-induced thrombocytopenia with hepatic dysfunction.
Topics: Aged; Anticoagulants; Arginine; Bilirubin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Heparin; Humans; Liver Diseases; Male; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Platelet Aggregation Inhibitors; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2006 |
Thrombotic end point for assessing argatroban therapy for heparin-induced thrombocytopenia: learning from secondary analyses of prospective studies.
Topics: Anticoagulants; Arginine; Cohort Studies; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2006 |
Effects of argatroban therapy, demographic variables, and platelet count on thrombotic risks in heparin-induced thrombocytopenia.
Topics: Aged; Amputation, Surgical; Anticoagulants; Arginine; Cohort Studies; Controlled Clinical Trials as Topic; Female; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Count; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2006 |
Increased venous versus arterial thrombosis in the Factor V Leiden mouse.
Topics: Amino Acid Substitution; Animals; Arginine; Arterial Occlusive Diseases; Arteries; Chlorides; Disease Models, Animal; Factor V; Ferric Compounds; Gene Frequency; Glutamine; Homozygote; Mice; Mice, Inbred C57BL; Mutation; Thrombosis; Venous Thrombosis | 2007 |
Oral L-arginine administration does not inhibit thrombosis on an experimental model of arterial thrombosis: the effect on the apyrasic activity of the arterial wall.
Topics: Adenosine Triphosphatases; Administration, Oral; Analysis of Variance; Animals; Aorta, Thoracic; Apyrase; Arginine; Blood Coagulation; Chi-Square Distribution; Femoral Artery; Male; Models, Animal; Platelet Aggregation; Rabbits; Statistics, Nonparametric; Thrombosis | 2006 |
Heparin-induced thrombocytopenia in patients administered heparin solely for hemodialysis.
Topics: Adult; Aged; Amputation, Surgical; Anticoagulants; Arginine; Dose-Response Relationship, Drug; Female; Heparin; Humans; Male; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Platelet Count; Registries; Renal Dialysis; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2006 |
Systemic anticoagulation with argatroban during arteriovenous dialysis graft thrombolysis.
Topics: Anticoagulants; Arginine; Hemofiltration; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Pipecolic Acids; Renal Dialysis; Sulfonamides; Thrombolytic Therapy; Thrombosis | 2006 |
Arginase activity is increased by thrombin: a mechanism for endothelial dysfunction in arterial thrombosis.
Topics: Arginase; Arginine; Biological Transport; Cells, Cultured; Endothelium, Vascular; Fibrin; Gene Expression; Humans; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Polymerase Chain Reaction; Receptors, Thrombin; RNA, Messenger; Thrombin; Thrombosis; Umbilical Veins | 2006 |
[Two surgical case reports showing atypical heparin-induced thrombocytopenia].
Topics: Adult; Anticoagulants; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Drug Eruptions; Female; Heparin; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Hirudins; Humans; Male; Pipecolic Acids; Platelet Count; Platelet Factor 4; Postoperative Complications; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis; Time Factors | 2007 |
Oxidative stress in cardiovascular disease: successful translation from bench to bedside?
Topics: Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Endothelium, Vascular; Hemorheology; Humans; Nitric Oxide; Oxidative Stress; Reactive Oxygen Species; Risk; Thrombosis; Vasodilation | 2007 |
Visual evaluation of blood coagulation during mural thrombogenesis under high shear blood flow.
Topics: Adult; Anticoagulants; Arginine; Blood Coagulation; Blood Flow Velocity; Blood Platelets; Collagen; Dose-Response Relationship, Drug; Factor VIIa; Fibrin; Hemolysis; Hemophilia A; Hemorheology; Heparin; Humans; Male; Microscopy, Confocal; Microscopy, Electron, Scanning; Middle Aged; Perfusion; Pipecolic Acids; Sulfonamides; Surface Properties; Thrombosis | 2008 |
Catheter-directed thrombolysis of acute lower extremity arterial thrombosis in a patient with heparin-induced thrombocytopenia.
Topics: Aged; Anticoagulants; Arginine; Arterial Occlusive Diseases; Catheterization, Peripheral; Fibrinolytic Agents; Heparin; Humans; Infusions, Intra-Arterial; Lower Extremity; Male; Pipecolic Acids; Radiography; Sulfonamides; Thrombocytopenia; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator; Treatment Outcome | 2007 |
[Are new anticoagulants better?].
Topics: Anticoagulants; Arginine; Drugs, Investigational; Factor Xa Inhibitors; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombin; Thrombosis; Warfarin | 2007 |
Improved blood compatibility of poly(ethylene terephthalate) films modified with L-arginine.
Topics: Absorption; Animals; Arginine; Biocompatible Materials; Blood; Blood Platelets; Cattle; Polyethylene Terephthalates; Quinolines; Serum Albumin, Bovine; Surface Properties; Thrombosis; Water | 2008 |
[Heparin induced thrombocytopenia and anticoagulation in renal replacemant therapy].
Topics: Acute Kidney Injury; Anticoagulants; Arginine; Blood Coagulation Tests; Chondroitin Sulfates; Citrates; Critical Care; Dermatan Sulfate; Diagnostic Errors; Dose-Response Relationship, Drug; Epoprostenol; Fondaparinux; Hemofiltration; Heparin; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Hirudins; Humans; Iloprost; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Sodium Citrate; Sulfonamides; Thrombocytopenia; Thrombosis | 2008 |
Prediction of the therapeutic index of marketed anti-coagulants and anti-platelet agents by guinea pig models of thrombosis and hemostasis.
Topics: Animals; Anticoagulants; Arginine; Arteriovenous Shunt, Surgical; Aspirin; Bleeding Time; Chlorides; Ferric Compounds; Guinea Pigs; Hemostasis; Male; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides; Thrombosis; Tirofiban; Tyrosine | 2008 |
Synthesis, nano-scale assembly, and in vivo anti-thrombotic activity of novel short peptides containing L-Arg and L-Asp or L-Glu.
Topics: Animals; Arginine; Aspartic Acid; Aspirin; Circular Dichroism; Dose-Response Relationship, Drug; Fibrinolytic Agents; Glutamic Acid; Nanostructures; Oligopeptides; Particle Size; Platelet Aggregation Inhibitors; Rats; Thrombosis | 2008 |
Suppression of in vivo injury-induced platelet thrombosis by inhibitors of adenosine diphosphate thrombotic activity.
Topics: Adenine Nucleotides; Animals; Arginine; Blood Platelet Disorders; Blood Platelets; Cricetinae; Drug Antagonism; Nucleosides; Thrombosis | 1967 |
[Substitution of antithrombin III by synthetic thrombin inhibitors].
Topics: Animals; Antithrombin III; Antithrombin III Deficiency; Arginine; Carbon Tetrachloride Poisoning; Fibrinogen; Heparin; Phenylpyruvic Acids; Pipecolic Acids; Platelet Count; Rats; Sulfonamides; Thrombin; Thrombosis | 1984 |
Role of the vascular endothelium.
Topics: Animals; Arginine; Arteries; Aspirin; Blood Platelets; Cattle; Cells, Cultured; Dansyl Compounds; Endothelium; Epoprostenol; Platelet Adhesiveness; Platelet Aggregation; Prostaglandins; Thrombin; Thrombosis | 1981 |
Comparative studies on thrombin inhibitors in experimental microthrombosis.
Topics: 4-Aminobenzoic Acid; Animals; Arginine; Dipeptides; Female; Fibrinogen; Hirudins; Kinetics; Lung; Male; Microcirculation; para-Aminobenzoates; Piperidines; Rats; Rats, Inbred Strains; Thrombin; Thrombosis | 1983 |
Tissue factor in microvesicles shed from U87MG human glioblastoma cells induces coagulation, platelet aggregation, and thrombogenesis.
Topics: Antibodies; Arginine; Blood Coagulation; Cell Line; Centrifugation, Density Gradient; Dansyl Compounds; Glioma; Humans; Neoplastic Stem Cells; Perfusion; Platelet Aggregation; Thromboplastin; Thrombosis | 1984 |
Pharmacologic control of blood coagulation by synthetic, low molecular weight inhibitors of clotting enzymes.
Topics: Amino Acid Chloromethyl Ketones; Animals; Arginine; Benzamidines; Binding Sites; Blood Coagulation; Catalysis; Disseminated Intravascular Coagulation; Endopeptidases; Molecular Weight; Protease Inhibitors; Rats; Serine Endopeptidases; Thrombin; Thrombosis | 1981 |
Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N alpha-substituted L-arginine.
Topics: Animals; Arginine; In Vitro Techniques; Lethal Dose 50; Thrombin; Thrombosis | 1980 |
Streptokinase-prostacyclin--nitric oxide: in vivo interactions.
Topics: Animals; Arginine; Aspirin; Blood Pressure; Cats; Epoprostenol; Extracorporeal Circulation; Fibrinolysis; Heparitin Sulfate; Iloprost; Infusions, Intravenous; Injections, Intravenous; Molsidomine; Nitric Oxide; Nitroarginine; Platelet Aggregation; Streptokinase; Thrombosis; Vasodilator Agents | 1995 |
Enhancement of thrombolytic efficacy of tissue-type plasminogen activator by adjuvants in the guinea pig thrombosis model.
Topics: Adjuvants, Pharmaceutic; Animals; Antithrombins; Arginine; Biphenyl Compounds; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Femoral Artery; Fibrinolytic Agents; Guinea Pigs; Heptanoic Acids; Indoles; Leukotriene Antagonists; Male; Microscopy, Electron, Scanning; Neutrophils; Pipecolic Acids; Platelet Aggregation Inhibitors; Receptors, Thromboxane; Recombinant Proteins; Sulfonamides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1994 |
Detailed examination of vascular lesions triggered by an inhibitor of endothelium-derived relaxing factor.
Topics: Animals; Arginine; Arterial Occlusive Diseases; Blood Pressure; Blood Vessels; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Hydralazine; Hypertension, Renovascular; Incidence; Microscopy, Electron; Nitric Oxide; Nitroarginine; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium; Thrombosis; Time Factors; Vascular Diseases | 1995 |
Antithrombotic actions of argatroban in rat models of venous, 'mixed' and arterial thrombosis, and its effects on the tail transection bleeding time.
Topics: Animals; Arginine; Arteriovenous Shunt, Surgical; Bleeding Time; Carotid Arteries; Electric Stimulation; Fibrinolytic Agents; Heparin; Male; Pipecolic Acids; Rats; Sulfonamides; Tail; Thrombophlebitis; Thrombosis | 1994 |
Thrombophilia: the new factor is old factor V.
Topics: Arginine; Factor V; Humans; Partial Thromboplastin Time; Point Mutation; Thrombosis | 1994 |
Brief report: variability of thrombosis among homozygous siblings with resistance to activated protein C due to an Arg-->Gln mutation in the gene for factor V.
Topics: Arginine; Base Sequence; Child; Exons; Factor V; Female; Glutamine; Homozygote; Humans; Male; Molecular Sequence Data; Mutation; Protein C; Thrombosis | 1994 |
Exogenous nitric oxide prevents endotoxin-induced glomerular thrombosis in rats.
Topics: Animals; Arginine; Blood Pressure; Kidney Diseases; Kidney Glomerulus; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Thrombosis | 1994 |
Glomerular thrombosis in pregnancy: role of the L-arginine-nitric oxide pathway.
Topics: Animals; Arginine; Endothelins; Escherichia coli; Female; Glomerular Mesangium; Lipopolysaccharides; Nitrates; Nitric Oxide; Nitrites; Pregnancy; Pregnancy Complications, Cardiovascular; Rats; Rats, Sprague-Dawley; Thrombosis | 1994 |
Antithrombin-Gly 424 Arg: a novel point mutation responsible for type 1 antithrombin deficiency and neonatal thrombosis.
Topics: Adult; Antithrombin III; Antithrombin III Deficiency; Arginine; Base Sequence; DNA; Female; Glycine; Humans; Infant, Newborn; Molecular Sequence Data; Pedigree; Point Mutation; Polymerase Chain Reaction; Thrombosis | 1994 |
Nitric oxide complements prostacyclin in the regulation of endothelial thromboresistance under flow conditions.
Topics: Animals; Aorta, Thoracic; Arginine; Aspirin; Blood Platelets; Endothelium, Vascular; Epoprostenol; In Vitro Techniques; Nitric Oxide; Nitroarginine; Rabbits; Thrombosis | 1993 |
The antithrombotic effect of low molecular weight synthetic thrombin inhibitors, argatroban and PPACK, on He-Ne laser-induced thrombosis in rat mesenteric microvessels.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antithrombins; Arginine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mesentery; Microcirculation; Pipecolic Acids; Platelet Aggregation; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombosis | 1993 |
An abnormal protein C (protein C Yonago) with an amino acid substitution of Gly for Arg-15 caused by a single base mutation of C to G in codon 57 (CGG-->GGG). Deteriorated calcium-dependent conformation of the gamma-carboxyglutamic acid domain relevant to
Topics: 1-Carboxyglutamic Acid; Amino Acid Sequence; Arginine; Base Sequence; Calcium; Codon; Glycine; Humans; Molecular Sequence Data; Mutation; Protein C; Protein Structure, Tertiary; Thrombosis | 1993 |
A Gla domain mutation (Arg 15-->Trp) in the protein C (PROC) gene causing type 2 protein C deficiency and recurrent venous thrombosis.
Topics: 1-Carboxyglutamic Acid; Arginine; Base Sequence; Conserved Sequence; Humans; Molecular Sequence Data; Mutation; Pedigree; Protein C; Protein C Deficiency; Recurrence; Thrombosis; Tryptophan | 1993 |
The combination of thrombin inhibitor and thromboxane synthase inhibitor on experimental thrombosis and bleeding.
Topics: Animals; Antithrombins; Arginine; Bleeding Time; Drug Synergism; Drug Therapy, Combination; Infusions, Intravenous; Male; Methacrylates; Pipecolic Acids; Rabbits; Sulfonamides; Thrombin; Thrombosis; Thromboxane-A Synthase | 1995 |
Molecular basis of a hereditary type I protein S deficiency caused by a substitution of Cys for Arg474.
Topics: Androgen-Binding Protein; Animals; Arginine; Base Sequence; Binding Sites; Cattle; Cell Line, Transformed; Chlorocebus aethiops; CHO Cells; Consanguinity; Cricetinae; Cysteine; DNA, Complementary; Female; Genetic Predisposition to Disease; Genetic Vectors; Humans; Laminin; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Protein S; Protein S Deficiency; Rabbits; Rats; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Thrombosis | 1996 |
Increased nitric oxide formation in recurrent thrombotic microangiopathies: a possible mediator of microvascular injury.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adolescent; Adult; Arginine; Cells, Cultured; Chromatography, High Pressure Liquid; Endothelium, Vascular; Female; Hemolytic-Uremic Syndrome; Humans; Male; Middle Aged; Neutrophils; Nitrates; Nitric Oxide; Nitrites; Purpura, Thrombotic Thrombocytopenic; Recurrence; Superoxides; Thrombosis; Tumor Necrosis Factor-alpha | 1996 |
Resistance to activated protein C (APC): mutation at Arg506 of coagulation factor V and vascular access thrombosis in haemodialysis patients.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Base Sequence; Catheters, Indwelling; Cohort Studies; DNA; DNA Primers; Factor V; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Pregnancy; Protein C; Renal Dialysis; Risk Factors; Thrombosis; Uremia | 1996 |
Arterial and venous thrombosis in two Italian families with the factor V Arg506-->Gln mutation.
Topics: Adult; Arginine; Base Sequence; Factor V; Female; Glutamine; Heterozygote; Homozygote; Humans; Italy; Male; Molecular Sequence Data; Mutation; Myocardial Infarction; Pedigree; Thrombophlebitis; Thrombosis | 1996 |
Inhibition by Argatroban, a specific thrombin inhibitor, of platelet activation by fibrin clot-associated thrombin.
Topics: Animals; Antithrombin III; Antithrombins; Arginine; Fibrin; Fibrinolytic Agents; Heparin; Hirudins; Pipecolic Acids; Platelet Activation; Platelet Aggregation Inhibitors; Rabbits; Recombinant Proteins; Sulfonamides; Thrombosis | 1996 |
Report of successful use of argatroban as an alternative anticoagulant during coronary stent implantation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome.
Topics: Aged; Angioplasty, Balloon, Coronary; Arginine; Coronary Angiography; Coronary Disease; Female; Heparin; Humans; Myocardial Infarction; Pipecolic Acids; Platelet Aggregation Inhibitors; Stents; Sulfonamides; Syndrome; Thrombocytopenia; Thrombosis | 1996 |
Low-molecular-weight heparin (fragmin) and thrombin active-site inhibitor (argatroban) compared in experimental arterial and venous thrombosis and bleeding time.
Topics: Animals; Antithrombins; Arginine; Bleeding Time; Dalteparin; Dose-Response Relationship, Drug; Fibrinolytic Agents; Male; Partial Thromboplastin Time; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombosis | 1996 |
Antithrombotic activity of argatroban in experimental thrombosis in the rabbit.
Topics: Animals; Antithrombins; Arginine; Disease Models, Animal; Dose-Response Relationship, Drug; Femoral Artery; Infusions, Intravenous; Pipecolic Acids; Rabbits; Sulfonamides; Thrombosis | 1996 |
Effects of inogatran, a new low-molecular-weight thrombin inhibitor, in rat models of venous and arterial thrombosis, thrombolysis and bleeding time.
Topics: Animals; Antithrombins; Arginine; Aspirin; Bleeding Time; Disease Models, Animal; Fibrinolytic Agents; Glycine; Heparin; Male; Molecular Weight; Pipecolic Acids; Piperidines; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombolytic Therapy; Thrombophlebitis; Thrombosis | 1996 |
Effect of argatroban on the formation of artificial thrombus on dogs.
Topics: Animals; Arginine; Dogs; Male; Osmolar Concentration; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides; Thrombosis; Ticlopidine | 1995 |
Low prevalence of activated protein C resistance and coagulation factor V Arg506 to Gln mutation among Japanese patients with various forms of thrombosis, and normal individuals.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Asian People; Case-Control Studies; Drug Resistance; Factor V; Female; Glutamine; Humans; Japan; Male; Middle Aged; Prevalence; Protein C; Thrombosis | 1996 |
Local delivery of antithrombotic drug prevents restenosis after balloon angioplasty in atherosclerotic rabbit artery.
Topics: Angiography; Angioplasty, Balloon, Coronary; Angioscopy; Animals; Antithrombins; Arginine; Arteriosclerosis; Batroxobin; Constriction, Pathologic; Fibrinolytic Agents; Fluorescein-5-isothiocyanate; Heparin, Low-Molecular-Weight; Iliac Artery; Male; Microscopy, Confocal; Pipecolic Acids; Rabbits; Sulfonamides; Thrombosis | 1996 |
Clinical features in 36 patients homozygous for the ARG 506-->GLN factor V mutation.
Topics: Adult; Aged; Arginine; Case-Control Studies; Extremities; Factor V; Female; Glutamine; Homozygote; Humans; Ischemia; Male; Middle Aged; Myocardial Infarction; Point Mutation; Risk Factors; Sex Characteristics; Thrombosis | 1997 |
Adjuvant effect of argatroban on staphylokinase induced thrombolysis of platelet rich thrombi in rat mesenteric venules in vivo.
Topics: Animals; Antithrombins; Arginine; Blood Platelets; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Fibrinolysis; Fibrinolytic Agents; Image Processing, Computer-Assisted; Male; Metalloendopeptidases; Microscopy, Electron; Pipecolic Acids; Rats; Rats, Wistar; Recombinant Proteins; Sulfonamides; Thrombosis | 1997 |
In vivo evaluation of DX-9065a, a synthetic factor Xa inhibitor, in experimental vein graft.
Topics: Animals; Anticoagulants; Antithrombins; Arginine; Blood Vessel Prosthesis; Disease Models, Animal; Factor Xa Inhibitors; Graft Occlusion, Vascular; Heparin; Male; Microscopy, Electron, Scanning; Naphthalenes; Pipecolic Acids; Propionates; Rabbits; Sulfonamides; Thrombosis | 1996 |
Factor X values as a means to assess the extent of oral anticoagulation in patients receiving antithrombin drugs.
Topics: Administration, Oral; Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Blood Coagulation Factors; Blood Coagulation Tests; Drug Monitoring; Drug Therapy, Combination; Factor X; False Positive Reactions; Female; Heparin; Humans; Indicators and Reagents; Male; Pipecolic Acids; Prothrombin Time; Reference Values; Reproducibility of Results; Sulfonamides; Thrombocytopenia; Thrombosis; Warfarin | 1997 |
Antithrombotic and hemorrhagic effects of DX-9065a, a direct and selective factor Xa inhibitor: comparison with a direct thrombin inhibitor and antithrombin III-dependent anticoagulants.
Topics: Animals; Anticoagulants; Antithrombin III; Arginine; Bleeding Time; Blood Coagulation; Disease Models, Animal; Factor Xa Inhibitors; Hemorrhage; Heparin, Low-Molecular-Weight; Male; Naphthalenes; Peptide Hydrolases; Pipecolic Acids; Propionates; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombosis | 1997 |
Electrospray ionisation mass spectrometry facilitates detection of fibrinogen (Bbeta 14 Arg --> Cys) mutation in a family with thrombosis.
Topics: Adult; Amino Acid Substitution; Arginine; Catalysis; Cysteine; Family Health; Female; Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Glycoproteins; Heterozygote; Humans; Mass Spectrometry; Molecular Weight; Mutation; Point Mutation; Polymerase Chain Reaction; Sequence Analysis; Thrombin; Thrombosis | 1997 |
Factor V Cambridge: a new mutation (Arg306-->Thr) associated with resistance to activated protein C.
Topics: Arginine; Drug Resistance; Factor V; Humans; Mutation; Protein C; Thrombosis | 1998 |
The first report of successful carotid stent implant using argatroban anticoagulation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome: a case report.
Topics: Aged; Anticoagulants; Antithrombins; Arginine; Carotid Arteries; Carotid Stenosis; Catheterization; Cerebrovascular Disorders; Femoral Artery; Follow-Up Studies; Heparin; Humans; Male; Paresis; Pipecolic Acids; Platelet Aggregation Inhibitors; Recurrence; Stents; Sulfonamides; Syndrome; Thrombocytopenia; Thrombosis | 1998 |
Ecarin Clotting Time: a predictive coagulation assay for the antithrombotic activity of argatroban in the rat.
Topics: Animals; Antithrombins; Arginine; Arteriovenous Shunt, Surgical; Blood Coagulation Tests; Disease Models, Animal; Male; Pipecolic Acids; Rats; Rats, Inbred Strains; Reference Values; Sulfonamides; Thrombophlebitis; Thromboplastin; Thrombosis; Treatment Outcome | 1998 |
Antithrombotic effects of YM-60828, a newly synthesized factor Xa inhibitor, in rat thrombosis models and its effects on bleeding time.
Topics: Animals; Anticoagulants; Arginine; Arteriovenous Shunt, Surgical; Bleeding Time; Blood Proteins; Dalteparin; Factor Xa Inhibitors; Fibrinolytic Agents; Heparin; In Vitro Techniques; Male; Naphthalenes; Partial Thromboplastin Time; Pipecolic Acids; Piperidines; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombophlebitis; Thrombosis | 1998 |
BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis--comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban.
Topics: Animals; Anticoagulants; Arginine; Arteries; Glycine; Heparin; Hirudins; Humans; Infusions, Intravenous; Oligopeptides; Peptide Fragments; Pipecolic Acids; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thrombin; Thrombosis; Veins | 1998 |
Activated protein C resistance: What have we learned now that the dust has settled?
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Arginine; Blood Coagulation Disorders; Cerebrovascular Disorders; Drug Resistance; Factor V; Female; Glutamine; Humans; Male; Middle Aged; Myocardial Infarction; Point Mutation; Protein C; Risk Factors; Thrombophlebitis; Thrombosis | 1997 |
Antithrombotic activity of a monoclonal antibody inducing the substrate form of plasminogen activator inhibitor type 1 in rat models of venous and arterial thrombosis.
Topics: Animals; Antibodies, Monoclonal; Anticoagulants; Arginine; Bleeding Time; Cross Reactions; Fibrinolytic Agents; Heparin; Humans; Male; Pipecolic Acids; Plasminogen Activator Inhibitor 1; Platelet Aggregation Inhibitors; Rats; Sulfonamides; Thrombosis; Venous Thrombosis | 1998 |
Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.
Topics: Amino Acid Sequence; Animals; Arginine; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; Chlorides; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Glass; Hemorrhage; Heparin; Hirudin Therapy; Hirudins; Molecular Sequence Data; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Sulfonamides; Thrombin; Thrombosis; Vena Cava, Inferior; Venous Thrombosis | 1999 |
Role of nitric oxide in restenosis after experimental balloon angioplasty in the hypercholesterolemic rabbit: effects on neointimal hyperplasia and vascular remodeling.
Topics: Angiography; Angioplasty, Balloon; Animals; Arginine; Arteriosclerosis; Disease Models, Animal; Enzyme Inhibitors; Follow-Up Studies; Hypercholesterolemia; Hyperplasia; Iliac Artery; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rabbits; Secondary Prevention; Thrombosis; Tunica Intima | 1999 |
Effects of voluntary exercise and L-arginine on thrombogenesis and microcirculation in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Blood Vessels; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Hypertension; Male; Microcirculation; Nitric Oxide; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Thrombosis | 1999 |
Use of argatroban during percutaneous coronary interventions in patients with heparin-induced thrombocytopenia.
Topics: Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Coronary Disease; Drug Evaluation; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 1999 |
Reduced nitric oxide production by L-arginine deficiency in lysinuric protein intolerance exacerbates intravascular coagulation.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Antithrombin III; Arginine; Blood Coagulation Disorders; Citrulline; Cyclic GMP; Humans; Lysine; Male; Nitric Oxide; Nitroglycerin; Ornithine; Peptide Hydrolases; Platelet Aggregation; Thrombosis | 1999 |
Design and synthesis of thrombin inhibitors: analogues of MD-805 with reduced stereogenicity and improved potency.
Topics: Animals; Antithrombins; Arginine; Cattle; Drug Design; Humans; Injections, Intravenous; Injections, Subcutaneous; Models, Molecular; Pipecolic Acids; Piperidines; Rats; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Thrombin; Thrombosis | 1999 |
Fibrinogen Bbeta14 Arg-->Cys: further evidence for a role in thrombosis.
Topics: Adult; Arginine; Cysteine; Female; Fibrinogen; Humans; Male; Point Mutation; Thrombosis | 1999 |
Local antithrombotic therapy using a novel porous balloon catheter.
Topics: Angioscopy; Animals; Arginine; Catheterization; Catheterization, Peripheral; Dogs; Fibrinolytic Agents; Heparin; Iliac Artery; Pipecolic Acids; Porosity; Sulfonamides; Thrombolytic Therapy; Thrombosis | 2000 |
Combination of a direct thrombin inhibitor and a platelet glycoprotein IIb/IIIa blocking peptide facilitates and maintains reperfusion of platelet-rich thrombus with alteplase.
Topics: Animals; Antithrombins; Arginine; Bleeding Time; Blood Flow Velocity; Blood Platelets; Disease Models, Animal; Drug Combinations; Drug Evaluation; Female; Femoral Artery; Fibrinolytic Agents; Heparin; Male; Partial Thromboplastin Time; Peptides; Peptides, Cyclic; Pipecolic Acids; Plasminogen Activators; Platelet Glycoprotein GPIIb-IIIa Complex; Rabbits; Reperfusion; Sulfonamides; Sulfoxides; Thrombosis; Tissue Plasminogen Activator | 2000 |
Antithrombotic effects of a synthetic inhibitor of activated factor X, JTV-803, in animals.
Topics: Animals; Anticoagulants; Antithrombin III; Arginine; Bleeding Time; Factor Xa Inhibitors; Fibrinolytic Agents; Heparin, Low-Molecular-Weight; Isoquinolines; Macaca fascicularis; Male; Partial Thromboplastin Time; Peptide Hydrolases; Pipecolic Acids; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrahydroisoquinolines; Thrombosis | 2001 |
Argatroban for treatment of heparin-induced thrombocytopenia.
Topics: Arginine; Health Expenditures; Hemorrhage; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2001 |
[Thrombogenicity and thromboresistance of vessels during postischemic reperfusion].
Topics: Animals; Arginine; Arterioles; Brain Ischemia; Epinephrine; Hindlimb; Intestine, Small; Male; Microcirculation; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Rats; Reperfusion Injury; Splanchnic Circulation; Thrombosis; Vasoconstrictor Agents; Venules | 1999 |
Anticoagulation with a selective thrombin inhibitor in a woman with heparin-induced thrombocytopenia.
Topics: Anticoagulants; Arginine; Catheterization, Central Venous; Female; Heparin; Humans; Middle Aged; Pipecolic Acids; Postoperative Complications; Sulfonamides; Thrombectomy; Thrombocytopenia; Thrombosis | 2001 |
Argatroban.
Topics: Antithrombins; Arginine; Drug Interactions; Humans; Pipecolic Acids; Sulfonamides; Thrombosis | 2001 |
L-arginine and thrombosis.
Topics: Arginine; Humans; Thrombosis | 2001 |
Inhibitors of fibrinolytic components play different roles in the formation and removal of arterial thrombus in mice.
Topics: alpha-2-Antiplasmin; Animals; Arginine; Bleeding Time; Blood Coagulation; Carotid Artery Injuries; Endothelium, Vascular; Mice; Mice, Inbred C57BL; Mice, Knockout; Pipecolic Acids; Piperazines; Piperidines; Plasminogen Activator Inhibitor 1; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Serine Proteinase Inhibitors; Sulfonamides; Thrombin; Thrombin Time; Thrombosis; Vascular Patency | 2002 |
Enhancement of endogenous plasminogen activator-induced thrombolysis by argatroban and APC and its control by TAFI, measured in an arterial thrombolysis model in vivo using rat mesenteric arterioles.
Topics: Animals; Arginine; Arterial Occlusive Diseases; Arterioles; Binding, Competitive; Carboxypeptidase B2; Enzyme Activation; Enzyme Inhibitors; Fibrinolysis; Fibrinolytic Agents; Image Processing, Computer-Assisted; Lasers; Male; Mesenteric Arteries; Models, Animal; Pipecolic Acids; Plant Proteins; Plasminogen Activators; Protease Inhibitors; Protein C; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Swine; Thrombosis | 2002 |
Argatroban therapy does not generate antibodies that alter its anticoagulant activity in patients with heparin-induced thrombocytopenia.
Topics: Antibodies; Anticoagulants; Arginine; Dose-Response Relationship, Drug; Heparin; Humans; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2002 |
Activation of the Hageman factor-prekallikrein system in the pathogenesis of the generalized Shwartzman reaction and of the hepatic vein thrombosis phenomenon in the rat.
Topics: Animals; Arginine; Bradykinin; Dexamethasone; Dimercaprol; Endotoxins; Esterases; Factor XII; Female; Hepatic Veins; Hyperlipidemias; Kallikreins; Kaolin; Male; Pregnancy; Prekallikrein; Rats; Shwartzman Phenomenon; Sulfinpyrazone; Thrombosis | 1979 |
[Disorders of hemostasis in malignant neoplasms].
Topics: Arginine; Blood Coagulation Disorders; Fibrin; Humans; Neoplasm Metastasis; Neoplasms; Thrombosis | 1977 |
Arginine aminopeptidase reactions to laser in vivo and in vitro.
Topics: Aminopeptidases; Animals; Arginine; Cheek; Cricetinae; Lasers; Muscles; Thrombosis | 1975 |
Endogenously synthesized nitric oxide prevents endotoxin-induced glomerular thrombosis.
Topics: Animals; Arginine; Blood Pressure; Cyclic GMP; Kidney Glomerulus; Lipopolysaccharides; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Proteinuria; Rats; Rats, Sprague-Dawley; Thrombosis | 1992 |
Synergistic antithrombotic properties of G4120, a RGD-containing synthetic peptide, and argatroban, a synthetic thrombin inhibitor, in a hamster femoral vein platelet-rich thrombosis model.
Topics: Animals; Antithrombins; Arginine; Aspirin; Blood Coagulation; Cricetinae; Disease Models, Animal; Drug Synergism; Femoral Vein; Fibrinolytic Agents; Hemostasis; Heparin; Injections, Intravenous; Male; Peptides, Cyclic; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Count; Sulfonamides; Sulfoxides; Thrombosis | 1992 |
[Experimental antithrombotic activity of oral isosorbide dinitrate].
Topics: Administration, Oral; Animals; Arginine; Aspirin; Isosorbide Dinitrate; Male; NG-Nitroarginine Methyl Ester; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Research Design; Thrombosis | 1992 |
Comparative antithrombotic effects of heparin, recombinant hirudin and argatroban in a hamster femoral vein platelet-rich mural thrombosis model.
Topics: Animals; Antithrombins; Arginine; Cricetinae; Femoral Vein; Heparin; Hirudin Therapy; Injections, Intravenous; Male; Models, Cardiovascular; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombin Time; Thrombosis | 1992 |
Heparin and the thrombin inhibitor argatroban enhance fibrinolysis by infused or bolus-injected saruplase (r-scu-PA) in rabbit femoral artery thrombosis.
Topics: Animals; Anticoagulants; Antithrombins; Arginine; Drug Synergism; Drug Therapy, Combination; Enzyme Precursors; Femoral Artery; Fibrinolysis; Heparin; Infusions, Intravenous; Injections, Intravenous; Pipecolic Acids; Plasminogen Activators; Rabbits; Recombinant Proteins; Sulfonamides; Thrombosis; Urokinase-Type Plasminogen Activator | 1991 |
Effect of ticlopidine and other antithrombotics on the venous thrombosis induced by endothelial damage of jugular vein in rats.
Topics: Animals; Arginine; Endothelium, Vascular; Fibrinolytic Agents; Freezing; Jugular Veins; Male; Microscopy, Electron, Scanning; Pipecolic Acids; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Sulfonamides; Thrombosis; Ticlopidine; Urokinase-Type Plasminogen Activator | 1991 |
In vivo thrombin inhibition enhances and sustains arterial recanalization with recombinant tissue-type plasminogen activator.
Topics: Animals; Antithrombins; Arginine; Blood Coagulation Tests; Female; Femoral Artery; Male; Pipecolic Acids; Rabbits; Sulfonamides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1990 |
Prevention of reocclusion by MCI-9038, a thrombin inhibitor, following t-PA-induced thrombolysis in a canine model of femoral arterial thrombosis.
Topics: Animals; Arginine; Arterial Occlusive Diseases; Disease Models, Animal; Dogs; Femoral Artery; Hemodynamics; Male; Pipecolic Acids; Recurrence; Regional Blood Flow; Sulfonamides; Thrombin; Thrombin Time; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 1990 |
Fibrin specific thrombolysis by two-chain urokinase-type plasminogen activator cleaved after arginine 156 by thrombin.
Topics: Amides; Amino Acid Sequence; Animals; Arginine; Electrophoresis, Polyacrylamide Gel; Fibrinolytic Agents; In Vitro Techniques; Jugular Veins; Molecular Sequence Data; Plasminogen Activators; Rabbits; Thrombin; Thrombosis; Urokinase-Type Plasminogen Activator | 1990 |
[Synthetic anticoagulant].
Topics: Animals; Antithrombins; Arginine; Dose-Response Relationship, Drug; Endothelins; Endothelium; Humans; Mice; Pipecolic Acids; Protein C; Receptors, Cell Surface; Receptors, Thrombin; Recombinant Proteins; Sulfonamides; Thrombosis | 1990 |
Prevention of platelet-rich arterial thrombosis by selective thrombin inhibition.
Topics: Animals; Antithrombins; Arginine; Arterial Occlusive Diseases; Bleeding Time; Blood Platelets; Femoral Artery; Graft Occlusion, Vascular; Heparin; In Vitro Techniques; Injections, Intra-Arterial; Injections, Intravenous; Pipecolic Acids; Rabbits; Regional Blood Flow; Sulfonamides; Thrombosis | 1990 |
A preliminary comparison of the thrombogenic activity of vitronectin and other RGD-containing proteins when bound to surfaces.
Topics: Adsorption; Animals; Arginine; Aspartic Acid; Biocompatible Materials; Blood Proteins; Dogs; Glycine; Glycoproteins; Humans; Polymers; Surface Properties; Thrombosis; Vitronectin | 1987 |
Protein C London 1: recurrent mutation at Arg 169 (CGG----TGG) in the protein C gene causing thrombosis.
Topics: Arginine; Base Sequence; Humans; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Protein C; Thrombosis | 1989 |
Antithrombotic effects of three thrombin inhibitors in a rat model of laser-induced thrombosis.
Topics: Animals; Antithrombins; Arginine; Disease Models, Animal; Hirudins; Humans; Injections, Intravenous; Lasers; Light Coagulation; Pipecolic Acids; Rats; Rats, Inbred Strains; Sulfonamides; Thrombosis | 1989 |
Single amino acid substitutions in the reactive site of antithrombin leading to thrombosis. Congenital substitution of arginine 393 to cysteine in antithrombin Northwick Park and to histidine in antithrombin Glasgow.
Topics: Amino Acid Sequence; Antithrombin III; Arginine; Cyanogen Bromide; Cysteine; Genetic Variation; Histidine; Humans; Mass Spectrometry; Molecular Sequence Data; Peptide Fragments; Serine Endopeptidases; Thrombosis; Trypsin | 1988 |
[Preventive effects of synthetic antithrombin, MD-805, on animal thrombosis models].
Topics: Acute Disease; Animals; Antithrombin III Deficiency; Antithrombins; Arginine; Arterial Occlusive Diseases; Mice; Pipecolic Acids; Pulmonary Embolism; Rats; Rats, Inbred Strains; Sulfonamides; Thrombosis; Vena Cava, Inferior | 1987 |
[Clinical evaluation of MD-805].
Topics: Aged; Antithrombins; Arginine; Disseminated Intravascular Coagulation; Drug Therapy, Combination; Female; Fibrinopeptide A; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Aggregation Inhibitors; Renal Dialysis; Sulfonamides; Thrombocytopenia; Thrombosis | 1987 |