arginine has been researched along with Bleeding in 146 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (7.53) | 18.7374 |
| 1990's | 31 (21.23) | 18.2507 |
| 2000's | 35 (23.97) | 29.6817 |
| 2010's | 59 (40.41) | 24.3611 |
| 2020's | 10 (6.85) | 2.80 |
| Authors | Studies |
|---|---|
| Dizdarevic, AM; Eyileten, C; Gasecka, A; Jarosz-Popek, J; Lang, IM; Nowak, A; Postula, M; Siller-Matula, JM; Ufnal, M; Wolska, M | 1 |
| Bilic, Z; Boban Blagaic, A; Brizic, I; Drmic, D; Gojkovic, S; Hriberski, K; Kalogjera, L; Kasnik, K; Knezevic, M; Kokot, A; Kralj, T; Krezic, I; Kubat, M; Lojo, N; Malekinusic, D; Milavic, M; Peklic, M; Seiwerth, S; Sever, M; Sikiric, P; Sikiric, S; Siroglavic, M; Skorak, I; Skrtic, A; Tvrdeic, A; Vladic, J; Vukojevic, J | 1 |
| Chen, HS; Cui, Y; Hou, XW; Li, XQ; Tian, XF; Wang, XH; Zhou, ZH | 1 |
| Chen, R; Guo, Y; Huang, Y; Jiang, J; Li, Y; Ren, J; Zhao, Q; Zhou, J | 1 |
| Jung, C; Leentjens, J; Middeldorp, S | 1 |
| Blagaic, AB; Drmic, D; Halle, ZB; Jandric, I; Kokot, A; Luetic, K; Seiwerth, RS; Seiwerth, S; Sever, AZ; Sikiric, P; Strinic, D; Sucic, M; Vuletic, LB; Zoricic, I | 1 |
| Bhatt, SH; Dobesh, PP; Glaubius, K; Trujillo, TC | 1 |
| Gulseth, MP; Kaide, CG | 1 |
| Boyle, G; Buchholz, H; Cantor, RS; Conway, J; Fynn-Thompson, F; Griffiths, E; Hawkins, B; Lorts, A; Lytrivi, ID; Machado, D; May, L; Niebler, RA; Rossano, J; Sutcliffe, DL; VanderPluym, CJ | 1 |
| Ansell, J; Baker, C; Bakhru, SH; Burnett, A; Chen, L; Jiang, X; Laulicht, BE; Steiner, S; Villano, S | 1 |
| Bergis, B; Chanson, N; Chassin, O; Drouot, S; Gleizes, O; Legris, N; Proulle, V; Ract, C; Walle, EM; Werner, M | 1 |
| Lai, CMB; Lee, AYY; Smith, T | 1 |
| Gkiatas, I; Korompilias, AV; Kostas-Agnantis, I; Papadopoulos, DV; Tsantes, AG; Ziara, P | 1 |
| Arslan, M; Karahan, SC; Koksal, I; Mentese, A; Yilmaz, G; Yilmaz, H | 1 |
| Abou Hammoud, A; Balabaud, C; Bioulac-Sage, P; Blanc, JF; Dartigues, B; Dugot-Senant, N; Dupuy, JW; Ezzoukry, Z; Henriet, E; Le Bail, B; Leste-Lasserre, T; Nikolski, M; Pallares-Lupon, N; Raymond, AA; Saltel, F | 1 |
| Fischer, AM; Godier, A; Martin, AC; Mauge, L; Smadja, DM | 1 |
| Ahmad, S; Ducruet, AF; Larkin, TM; Lauver, MA; Zhao, XJ | 1 |
| Almegren, M | 1 |
| Banik, N; Beyer-Westendorf, J; Brachmann, J; Dohmen, PM; Eberle, S; Hankowitz, J; Klamroth, R; Kropff, S; Lindhoff-Last, E; Madlener, K; Müller, MM; Pötzsch, B; Schellong, S; Schindewolf, M; Steindl, J | 1 |
| Douketis, J; Levy, JH; Weitz, JI | 1 |
| Gheysens, O; Goffin, KE; Hoylaerts, MF; Jacquemin, M; Liesenborghs, L; Peerlinck, K; Peetermans, M; Peetermans, WE; Vanassche, T; Verhaegen, J; Verhamme, P; Wijngaerden, EV | 1 |
| Bianchini, EP; Borgel, D; Fazavana, J; Picard, V; Saller, F; Smadja, C; Taverna, M | 1 |
| Pötzsch, B | 1 |
| Babu, BI; Jamdar, S; Jeziorska, M; McMahon, RF; Nirmalan, M; Siriwardena, AK | 1 |
| Burger, CF; Schlesinger, JJ | 1 |
| Cao, FF; Feng, X; Jiao, RN; Zhang, HT | 1 |
| Moffett, BS; Teruya, J | 1 |
| Bahlmann, A; Beiderlinden, M; Brezina, T; Geib, J; Golla, E; Greinacher, A; Kienbaum, P; Kindgen-Milles, D; Pannen, B; Schaefer, MS; Treschan, TA; Werner, P | 1 |
| Lin, JK; Tong, LM; Vo, QA | 1 |
| Baumgarten, G; Boehm, O; Graeff, I; Hoeft, A; Kim, SC; Schewe, JC; Tran, N; Wittmann, M | 1 |
| Bojic, D; Drmic, D; Hrelec Patrlj, M; Kokot, A; Kolenc, D; Radic, B; Seiwerth, S; Sikiric, P; Stupnisek, M; Suran, J; Vcev, A; Zenko Sever, A | 1 |
| Berkowitz, SD; Costin', J; Curnutte, JT; Gibson, CM; Hoffman, M; Kaminskas, E; Kowey, PR; Krucoff, MW; Levy, JH; Mintz, PD; Reilly, PA; Sager, PT; Sarich, TC; Seltzer, JH; Singer, DE; Stockbridge, N; Weitz, JI | 1 |
| Crowther, M; Crowther, MA | 1 |
| Bain, J; Meyer, A | 1 |
| Arslan, S; Basuguy, E; Bozdag, Z; Ibiloglu, I; Kaplan, I; Okur, MH; Turkoglu, A; Uluca, U; Zeytun, H | 1 |
| Cuker, A; Siegal, D | 1 |
| Fushimi, K; Horiguchi, H; Matsubara, T; Nakajima, S; Wada, T; Yahagi, N; Yasunaga, H | 1 |
| Agewall, S; Atar, D; Drexel, H; Husted, SE; Kaski, JC; Kjeldsen, K; Koller, L; Lewis, BS; Lip, GYH; Morais, J; Niessner, A; Storey, RF; Tamargo, J; Torp-Pedersen, C; Verheugt, FWA; Wassmann, S | 1 |
| Gómez-Outes, A; Lecumberri, R | 1 |
| Ageno, W; Chan, NC; Crowther, M; Levy, JH; Verhamme, P; Weitz, JI | 1 |
| Asirvatham, SJ; Hu, TY; Vaidya, VR | 1 |
| Fanikos, J; Smythe, MA; Trujillo, T | 1 |
| Hussain, SS; Mukherjee, D; Tyroch, AH | 1 |
| Antman, EM; Giugliano, RP; Ruff, CT | 1 |
| Fanikos, J; Huisman, MV | 2 |
| Levy, JH | 2 |
| Kaatz, S; Milling, TJ | 2 |
| Baumgarten, G; Kim, S; Koster, A; Riedel, R; Schewe, JC; Schmieder, A | 1 |
| Bhagirath, VC; Eikelboom, JW; Monagle, S; Ng, KH | 1 |
| Iwaki, T; Kanayama, N; Nagahashi, K; Suzuki-Inoue, K; Takano, K; Umemura, K; Urano, T | 1 |
| Desborough, MJ; Shapiro, S; Zhang, XY | 1 |
| Baron, SJ; Cruz-Gonzalez, I; Healy, JL; Jang, IK; Osakabe, M; Sanchez-Ledesma, M; Watanabe, H; Yeh, RW | 1 |
| Hursting, MJ; Verme-Gibboney, CN | 1 |
| Baron, SJ; Cruz-Gonzalez, I; Healy, JL; Jang, IK; McNulty, IA; Pomerantsev, E; Yeh, RW | 1 |
| Dangas, G | 1 |
| Jianping, N; Siyuan, D; Yanchao, L; Yixiong, Z | 1 |
| Buerke, M; Desaga, M; Genth-Zotz, S; Gulba, DC; Harder, S; Heyndrickx, GR; Rau, M; Rössig, L; Schneider, T; Zeiher, AM | 1 |
| Boyle, DA; Choi, YM; Cox, DS; Gobburu, JV; Hossain, M; Madabushi, R; Patel, BR; Young, G | 1 |
| Agnihotri, AK; Hoffman, WD; Jang, IK; Nam, KH; Yeh, RW; Yoon, JH | 1 |
| Bandyk, DF; Bartholomew, JR; Boyce, SW; Frame, JN; Rice, L | 1 |
| Smythe, MA; Warkentin, TE; Woodhouse, AL; Zakalik, D | 1 |
| Chen, X; Chen, Y; Ma, Z; Sun, X; Wang, Y; Xiang, J; Xiao, Q; Zhou, J | 1 |
| Boshkov, LK; Boyle, DA; Cox, DS; Hursting, MJ; Kallender, H; Raffini, LJ; Soffer, J; Sullivan, JE; Tarka, EA; Young, G | 1 |
| Bradley, AM; Branan, T | 1 |
| Artuković, B; Cenan, S; Cooper, RG; Dinarina-Sablić, M; Dzaja, P; Grabarević, Z; Tisljar, M; Zelenika, TA | 1 |
| Demma, LJ; Levy, JH; Paciullo, CA | 1 |
| Doepker, B; Gerlach, AT; Mount, KL; Murphy, CV; Philips, GS; Ryder, LJ | 1 |
| Knovich, MA; Lesser, GJ; Strowd, RE | 1 |
| Cooper, T; Kokko, H; Mazur, J; Taber, D; Uber, WE; White, CL | 1 |
| Mizuno, Y; Noda, K; Tanaka, R; Urabe, T | 1 |
| Herrmann, HW; Kuch, U; Mebs, D; Ziegler, T | 1 |
| Buijsman, R; Meuleman, DG; Princen, AW; Smit, MJ; Van Dinther, TG; Vogel, GM | 1 |
| DAVIDSON, CS | 1 |
| Bilgic, H; Deveci, S; Korkmaz, A; Oter, S; Ozgurtas, T; Sadir, S; Topal, T | 1 |
| Bilgic, H; Korkmaz, A; Oter, S; Oztas, E; Topal, T; Yildirim, I | 1 |
| Bartholomew, JR; Hursting, MJ | 1 |
| Angele, MK; Angele, P; Chaudry, IH; Hernandez-Richter, T; Jauch, KW; Mayr, S; Prix, N; van den Engel, NK; Wichmann, MW; Wittmann, F | 1 |
| McIntosh, BA | 1 |
| Koerber, JM; Mattson, JC; Smythe, MA; Stephens, JL | 1 |
| Katz, E; Kim, KY; McNulty, I | 1 |
| Chen, Y; Guo, XJ; Wang, CY; Wang, L; Wu, HS; Xu, JB; Zhang, JH; Zhang, L | 1 |
| Aghababian, RV; Begelman, SM; Hursting, MJ; McCollum, D | 1 |
| Hursting, MJ; Lewis, BE | 1 |
| Arnolda, LF; Holobotovskyy, VV; Malik, V; McKitrick, DJ; Phillips, JK | 1 |
| Fischer, KG | 1 |
| Beiderlinden, M; Görlinger, K; Peters, J; Treschan, TA | 1 |
| Kääpä, P; Kiss, J; Savunen, T | 1 |
| Hursting, MJ; Jang, IK | 1 |
| Ahmed, I; Majeed, A; Powell, R | 1 |
| Lepor, NE | 1 |
| Warkentin, TE | 1 |
| Asher, LV; Atkins, JL; Gorbunov, NV; Hammamieh, R; Jett, M; Kiang, JG | 1 |
| Bauer, I; Heiser, J; Kubulus, D; Mathes, A; Pavlidis, D; Pradarutti, S; Raddatz, A; Rensing, H; Wolf, B | 1 |
| Ganthavorn, S; Toom, PM; Tu, AT | 1 |
| Chi, OZ; Sinha, AK; Wei, HM; Weiss, HR | 1 |
| Moncada, S; Radomski, MW | 1 |
| Balla, I; Dawson, TM; Kovách, AG; Lohinai, Z; Marczis, J; Snyder, SH | 1 |
| Dabrowski, A; Gabryelewicz, A | 1 |
| Hasser, EM; Koch, MA; Schadt, JC | 1 |
| Ekelund, U; Mellander, S | 1 |
| Chiu, T; Reid, IA | 1 |
| Krieger, EM; Xavier-Neto, J | 1 |
| Castaneda, A; Hernandez, R; Myers, SI | 1 |
| Philippu, A; Schneider, C; Singewald, N | 1 |
| Lieberthal, W; McGarry, AE; Thompson, A; Valeri, CR | 1 |
| Clark, DA; Diket, AL; Eloby-Childress, S; Greenberg, SS; Miller, MJ; Munshi, UK; Pierce, MR; Voelker, CA; Zhang, XJ | 1 |
| Buchanan, MR; Houston, DS | 1 |
| Mulligan, MS; Seekamp, A; Till, GO; Ward, PA | 1 |
| Ludbrook, J; Ventura, S | 1 |
| Verstraete, M | 1 |
| Greenberg, JH; Jaggi, JL; Komjáti, K; Kovách, AG; Nyáry, I; Reivich, M; Sándor, P | 1 |
| Hara, T; Kunitada, S; Morishima, Y; Tanabe, K; Terada, Y | 1 |
| Hirayama, F; Kawasaki, T; Koshio, H; Matsumoto, Y; Sato, K; Taniuchi, Y | 1 |
| Du, XY; Jin, Y; Pan, H; Wu, XF; Zhou, YC; Zhu, H | 1 |
| Angele, MK; Bland, KI; Chaudry, IH; Cioffi, WG; Smail, N; Wang, P | 1 |
| Angele, MK; Ayala, A; Chaudry, IH; Cioffi, WG; Knöferl, MW; Smail, N | 1 |
| Fukazawa, T; Goto, Y; Hayashi, H; Inoue, Y; Komatsu, Y | 1 |
| Benyó, Z; Kovách, AG; Sándor, P; Szabó, C | 1 |
| Jang, IK; Januzzi, JL | 1 |
| Abe, Y; Fujisawa, Y; Miyanaka, H; Miyatake, A; Mori, N; Yube, K | 1 |
| Noris, M; Remuzzi, G | 1 |
| Ahmad, S; Ahsan, A; Fareed, J; Hoppensteadt, DA; Iqbal, O; Lewis, BE; Walenga, JM | 1 |
| Angele, MK; Ayala, A; Chaudry, IH; Fitzal, F; Knöferl, MW; Schwacha, MG; Smail, N; Wang, P | 1 |
| Besse, P; Darius, H; Fels, PW; Fitzgerald, D; Garrigou, D; Müller, E; Puel, J; Simoons, ML; Vahanian, A; Van de Werf, F; Vermeer, F | 1 |
| Bartholomew, J; Berkowitz, SD; Fareed, J; Hursting, MJ; Jang, IK; Kelton, JG; Lerner, RG; Lewis, BE; Matthai, WH; Moran, J; Rifkin, SD; Rustagi, PK; Sham, R; Walenga, JM; Wallis, DE; Zeigler, ZR | 1 |
| Prostran, M; Todorović, Z; Vucković, S | 1 |
| Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H | 1 |
| Corno, A; Horisberger, J; Marty, B; Mueller, X; von Segesser, LK | 1 |
| Cho, JH; Dan, T; Kim, HY; Koga, T; Koo, BA; Seo, HS; Yun, CH | 1 |
| Lieberthal, W; McGarry, AE; Sheils, J; Valeri, CR | 1 |
| Boughton-Smith, NK; Hutcheson, IR; Whittle, BJ | 1 |
| Corna, D; Macconi, D; Perico, N; Remuzzi, G; Viganò, G; Zoja, C | 1 |
| Ouyang, C; Shiau, SY | 1 |
| Adams, DA; Dashe, AM; Gipstein, RM; Heuser, G; Rand, RW; Roth, NH | 1 |
| Burton, AM; Forsling, ML; Martin, MJ; Sturdy, JC | 1 |
| Field, JB; Finster, JL; Mintz, DH; Raskin, P; Taylor, AL | 1 |
| de Vries, A; Hahn, J; Moroz, C | 1 |
| Burton, AM; Forsling, ML; Martin, MJ | 1 |
| Aziz, O | 1 |
| De Wardener, HE; Fabian, M; Jones, JJ; Lee, J; Schrier, RW; Verroust, PJ | 1 |
| Fabian, M; Forsling, ML; Jones, JJ; Lee, J | 1 |
38 review(s) available for arginine and Bleeding
| Article | Year |
|---|---|
A short review of ciraparantag in perspective of the currently available anticoagulant reversal agents.
Topics: Administration, Oral; Anticoagulant Reversal Agents; Anticoagulants; Anticoagulation Reversal; Antidotes; Arginine; Hemorrhage; Heparin; Humans; Piperazines; Recombinant Proteins | 2022 |
Antidotes for reversal of direct oral anticoagulants.
Topics: Animals; Antibodies, Monoclonal, Humanized; Arginine; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins | 2019 |
Current Strategies for the Management of Bleeding Associated with Direct Oral Anticoagulants and a Review of Investigational Reversal Agents.
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Factors; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Practice Guidelines as Topic; Recombinant Proteins | 2020 |
The role of new oral anticoagulants in orthopaedics: an update of recent evidence.
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Tests; Dabigatran; Factor Xa; Hemorrhage; Humans; Orthopedic Procedures; Piperazines; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles; Venous Thromboembolism | 2017 |
[State of the art: Direct oral anticoagulants and transfusion].
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Antidotes; Antithrombins; Arginine; Blood Coagulation Factors; Blood Transfusion; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hemostatics; Humans; Piperazines; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Stroke; Thrombophilia | 2017 |
Reversal of direct oral anticoagulants.
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation; Coagulants; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Risk Factors; Treatment Outcome | 2017 |
Reversal agents for non-vitamin K antagonist oral anticoagulants.
Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Blood Loss, Surgical; Coagulants; Factor Xa; Hemorrhage; Humans; Perioperative Care; Piperazines; Postoperative Hemorrhage; Recombinant Proteins; Risk Assessment; Risk Factors; Treatment Outcome | 2018 |
Argatroban: for a few selected patients.
Topics: Anticoagulants; Antithrombins; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Drug Interactions; Drug Substitution; Hemorrhage; Heparin; Heparitin Sulfate; Humans; Patient Selection; Pipecolic Acids; Risk Assessment; Risk Factors; Sulfonamides; Thrombocytopenia; Treatment Outcome; Venous Thrombosis | 2013 |
[Anticoagulation].
Topics: Administration, Oral; Anticoagulants; Antithrombins; Arginine; Arrhythmias, Cardiac; Blood Coagulation Tests; Factor Xa Inhibitors; Hemorrhage; Heparin; Heparinoids; Hirudins; Humans; Infusions, Intravenous; Orthopedic Procedures; Peptide Fragments; Pipecolic Acids; Postoperative Complications; Pulmonary Embolism; Recombinant Proteins; Risk Factors; Secondary Prevention; Sulfonamides; Thromboembolism; Treatment Outcome; Venous Thrombosis; Vitamin K | 2013 |
[Meta-analysis of the role of Argatroban in renal replacement therapy].
Topics: Antithrombins; Arginine; Hemorrhage; Humans; Incidence; Pipecolic Acids; Renal Dialysis; Renal Insufficiency; Renal Replacement Therapy; Sulfonamides; Thrombosis | 2013 |
Antidotes for novel oral anticoagulants: current status and future potential.
Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Coagulants; Hemorrhage; Humans; Piperazines; Risk Assessment; Risk Factors; Treatment Outcome | 2015 |
Monitoring and reversal of direct oral anticoagulants.
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Factors; Blood Coagulation Tests; Dabigatran; Factor VIIa; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hemostasis; Humans; Partial Thromboplastin Time; Piperazines; Prothrombin; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles; Thrombin Time | 2015 |
When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH.
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Coagulants; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins | 2016 |
Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab.
Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Blood Coagulation Tests; Coagulants; Drug Monitoring; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins | 2016 |
Reversal agents for use with direct and indirect anticoagulants.
Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins | 2016 |
Reversal of Newer Direct Oral Anticoagulant Drugs (DOACs).
Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antifibrinolytic Agents; Arginine; Blood Coagulation; Blood Coagulation Factors; Cardiovascular Diseases; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Models, Molecular; Piperazines; Recombinant Proteins | 2017 |
Management of Bleeding With Non-Vitamin K Antagonist Oral Anticoagulants in the Era of Specific Reversal Agents.
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Antithrombins; Arginine; Blood Coagulation Factors; Dabigatran; Factor VIIa; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hemostatics; Humans; Piperazines; Plasma; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles | 2016 |
Idarucizumab and Factor Xa Reversal Agents: Role in Hospital Guidelines and Protocols.
Topics: Antibodies, Monoclonal, Humanized; Antidotes; Antithrombins; Arginine; Blood Coagulation Factors; Clinical Protocols; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hospitals; Humans; Piperazines; Practice Guidelines as Topic; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban | 2016 |
Discontinuation and Management of Direct-Acting Anticoagulants for Emergency Procedures.
Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Antithrombins; Arginine; Dabigatran; Deprescriptions; Emergencies; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Humans; International Normalized Ratio; Piperazines; Prothrombin Time; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Surgical Procedures, Operative | 2016 |
Preclinical and Clinical Data for Factor Xa and "Universal" Reversal Agents.
Topics: Animals; Antidotes; Arginine; Atrial Fibrillation; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Stroke; Thromboembolism | 2016 |
Idarucizumab and factor Xa reversal agents: role in hospital guidelines and protocols.
Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Clinical Protocols; Dabigatran; Emergency Treatment; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hospitals; Humans; Patient Selection; Piperazines; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Surgical Procedures, Operative; Thiazoles | 2016 |
Discontinuation and management of direct-acting anticoagulants for emergency procedures.
Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Tests; Emergency Treatment; Factor Xa; Hemorrhage; Humans; Perioperative Care; Piperazines; Recombinant Proteins; Withholding Treatment | 2016 |
Preclinical and clinical data for factor Xa and "universal" reversal agents.
Topics: Animals; Anticoagulants; Arginine; Clinical Trials as Topic; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins | 2016 |
[Heparin-induced thrombocytopenia type II (HIT II) : A medical-economic view].
Topics: Arginine; Chondroitin Sulfates; Costs and Cost Analysis; Dermatan Sulfate; Germany; Hemorrhage; Heparin; Heparitin Sulfate; Hospitalization; Humans; Pipecolic Acids; Risk Factors; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome | 2017 |
Clinical implications of reversal agents for direct oral anticoagulants.
Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Antithrombins; Arginine; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles; Venous Thromboembolism | 2017 |
Reversal of direct oral anticoagulants.
Topics: Aged; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Antithrombins; Arginine; Blood Coagulation Factors; Coagulants; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Intracranial Hemorrhages; Male; Partial Thromboplastin Time; Piperazines; Prothrombin Time; Recombinant Proteins; Thrombin Time | 2017 |
HEPATIC COMA.
Topics: Ammonia; Anti-Bacterial Agents; Arginine; Blood; Diagnosis; Diagnosis, Differential; Diuretics; Gastrointestinal Hemorrhage; Glutamates; Hemorrhage; Hepatic Encephalopathy; Humans; Hypnotics and Sedatives; Metabolism; Pathology; Surgical Procedures, Operative; Toxicology; Water-Electrolyte Balance | 1964 |
Developing an algorithm for treating heparin-induced thrombocytopenia.
Topics: Algorithms; Anticoagulants; Antigen-Antibody Complex; Arginine; Clinical Trials as Topic; Diagnosis, Differential; Disease Management; Follow-Up Studies; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Immunoglobulin G; Pipecolic Acids; Platelet Activation; Platelet Count; Platelet Factor 4; Prognosis; Purpura, Thrombocytopenic, Idiopathic; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombophilia; Time Factors | 2004 |
Direct thrombin inhibition during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.
Topics: Angioplasty, Balloon, Coronary; Antithrombins; Arginine; Drug Interactions; Economics, Pharmaceutical; Fibrinolytic Agents; Hemorrhage; Heparin; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis | 2007 |
Essentials of anticoagulation in hemodialysis.
Topics: Anticoagulants; Arginine; Blood Coagulation; Chondroitin Sulfates; Dermatan Sulfate; Equipment Failure; Hemorrhage; Heparin; Heparitin Sulfate; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Renal Dialysis; Renal Insufficiency, Chronic; Sulfonamides | 2007 |
Heparin induced thrombocytopenia: diagnosis and management update.
Topics: Anticoagulants; Arginine; Cardiovascular Surgical Procedures; Chondroitin Sulfates; Dermatan Sulfate; Fibrinolytic Agents; Hemorrhage; Heparin; Heparitin Sulfate; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Renal Dialysis; Sulfonamides; Thrombocytopenia; Warfarin | 2007 |
Anticoagulation for acute coronary syndromes: from heparin to direct thrombin inhibitors.
Topics: Acute Disease; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Fondaparinux; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Models, Molecular; Molecular Structure; Myocardial Ischemia; Peptide Fragments; Pipecolic Acids; Platelet Activation; Polysaccharides; Recombinant Proteins; Sulfonamides; Syndrome; Thrombin; Thrombosis | 2007 |
The biological and pharmacological role of nitric oxide in platelet function.
Topics: Amino Acid Oxidoreductases; Arginine; Arteriosclerosis; Blood Platelets; Endothelium, Vascular; Enzyme Induction; Guanylate Cyclase; Hemorrhage; Hemostasis; Humans; Iron-Sulfur Proteins; Isoenzymes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation; Thrombosis; Vasodilation | 1993 |
Direct thrombin inhibitors: appraisal of the antithrombotic/hemorrhagic balance.
Topics: Antithrombins; Arginine; Clinical Trials, Phase III as Topic; Fibrinolytic Agents; Hemorrhage; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides | 1997 |
Heparin induced thrombocytopenia: diagnosis and contemporary antithrombin management.
Topics: Ancrod; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Drug Combinations; Fibrinolytic Agents; Forecasting; Gangrene; Hemorrhage; Heparin; Heparitin Sulfate; Hirudin Therapy; Hirudins; Humans; Pipecolic Acids; Platelet Aggregation; Protein C; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Warfarin | 1999 |
Uremic bleeding: closing the circle after 30 years of controversies?
Topics: Anemia; Animals; Arginine; Bleeding Time; Blood Platelets; Endothelium, Vascular; Enzyme Inhibitors; Erythropoietin; Guanidines; Hemorrhage; History, 18th Century; History, 20th Century; Humans; Isoenzymes; Kidney Failure, Chronic; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Succinates; Uremia | 1999 |
Anticoagulation: the present and future.
Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis | 2001 |
Alternatives to unfractionated heparin for anticoagulation in cardiopulmonary bypass.
Topics: Abciximab; Ancrod; Antibodies, Monoclonal; Anticoagulants; Arginine; Cardiopulmonary Bypass; Chondroitin Sulfates; Cross Reactions; Dermatan Sulfate; Drug Combinations; Drug Hypersensitivity; Factor Xa Inhibitors; Hemodilution; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Hirudin Therapy; Humans; Immunoglobulin Fab Fragments; Perfusion; Pipecolic Acids; Platelet Aggregation Inhibitors; Protamines; Sulfonamides; Thrombocytopenia; Thrombophilia; Thrombosis; Tirofiban; Tyrosine | 2001 |
15 trial(s) available for arginine and Bleeding
| Article | Year |
|---|---|
Safety and preliminary efficacy of argatroban plus dual antiplatelet therapy for acute mild to moderate ischemic stroke with large artery atherosclerosis.
Topics: Arginine; Arteries; Atherosclerosis; Hemorrhage; Humans; Intracranial Hemorrhages; Ischemic Stroke; Pipecolic Acids; Platelet Aggregation Inhibitors; Prospective Studies; Retrospective Studies; Sulfonamides; Treatment Outcome | 2022 |
Ciraparantag, an anticoagulant reversal drug: mechanism of action, pharmacokinetics, and reversal of anticoagulants.
Topics: Animals; Anticoagulants; Arginine; Blood Coagulation; Female; Half-Life; Hemorrhage; Humans; Male; Piperazines; Rats; Rats, Sprague-Dawley | 2021 |
Targeting Coagulase Activity in Staphylococcus aureus Bacteraemia: A Randomized Controlled Single-Centre Trial of Staphylothrombin Inhibition.
Topics: Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Bacteremia; Belgium; Blood Coagulation; Coagulase; Dabigatran; Enoxaparin; Feasibility Studies; Female; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Pilot Projects; Pipecolic Acids; Prospective Studies; Staphylococcal Infections; Staphylococcus aureus; Sulfonamides; Thrombin; Thrombosis; Time Factors; Treatment Outcome | 2018 |
Argatroban versus Lepirudin in critically ill patients (ALicia): a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Critical Illness; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Recombinant Proteins; Renal Insufficiency; Renal Replacement Therapy; Sulfonamides; Surgical Procedures, Operative; Thrombocytopenia | 2014 |
Low dose of argatroban saline flushes anticoagulation in hemodialysis patients with high risk of bleeding.
Topics: Anticoagulants; Arginine; Dose-Response Relationship, Drug; Female; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Renal Dialysis; Sodium Chloride; Sulfonamides | 2010 |
Argatroban for elective percutaneous coronary intervention: the ARG-E04 multi-center study.
Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Blood Coagulation; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombosis | 2011 |
A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis: PREVENT-HIT Study.
Topics: Adolescent; Adult; Aged; Anticoagulants; Arginine; Disease Progression; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Pilot Projects; Pipecolic Acids; Platelet Count; Postoperative Complications; Postoperative Period; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis; Treatment Outcome; Young Adult | 2011 |
Bleeding risk factors associated with argatroban therapy in the critically ill.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Bilirubin; Critical Illness; Female; Hemoglobins; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Count; Retrospective Studies; Risk Factors; Sulfonamides | 2012 |
Anticoagulant therapy with a selective thrombin inhibitor for acute cerebral infarction: usefulness of coagulation markers for evaluation of efficacy.
Topics: Acute Disease; Aged; Anticoagulants; Antithrombins; Arginine; Biomarkers; Blood Coagulation; Blood Coagulation Tests; Blood Proteins; Cerebral Infarction; Embolism; Female; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Stroke; Sulfonamides; Thrombosis; Treatment Outcome | 2002 |
Transitioning from argatroban to warfarin in heparin-induced thrombocytopenia: an analysis of outcomes in patients with elevated international normalized ratio (INR).
Topics: Adult; Aged; Amputation, Surgical; Arginine; Cause of Death; Female; Hemorrhage; Heparin; Humans; Incidence; International Normalized Ratio; Male; Middle Aged; Pipecolic Acids; Retrospective Studies; Risk Assessment; Sulfonamides; Survival Rate; Thrombocytopenia; Thrombosis; Treatment Outcome; Warfarin | 2005 |
Thrombocytopenia following heparin flush.
Topics: Amputation, Surgical; Anticoagulants; Arginine; Catheters, Indwelling; Cause of Death; Diagnosis, Differential; Female; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Male; Middle Aged; Partial Thromboplastin Time; Patient Selection; Pipecolic Acids; Platelet Count; Prospective Studies; Recurrence; Sulfonamides; Therapeutic Irrigation; Thrombocytopenia; Thrombosis; Treatment Outcome | 2005 |
Argatroban anticoagulation in critically ill patients.
Topics: Anticoagulants; Arginine; Critical Illness; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Multiple Organ Failure; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombocytopenia | 2007 |
Clinical laboratory monitoring of a synthetic antithrombin agent, argatroban, using high performance liquid chromatography and functional methods.
Topics: Anticoagulants; Antithrombins; Arginine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Hemorrhage; Humans; Male; Myocardial Infarction; Pipecolic Acids; Sensitivity and Specificity; Streptokinase; Sulfonamides; Time Factors | 1999 |
Argatroban and alteplase in patients with acute myocardial infarction: the ARGAMI Study.
Topics: Aged; Angiography; Anticoagulants; Arginine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Partial Thromboplastin Time; Pipecolic Acids; Plasminogen Activators; Sulfonamides; Survival Rate; Time Factors; Tissue Plasminogen Activator | 2000 |
Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia.
Topics: Aged; Anticoagulants; Arginine; Blood Coagulation; Blood Coagulation Tests; Diarrhea; Exanthema; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pain; Pipecolic Acids; Purpura; Sulfonamides; Thrombocytopenia; Treatment Outcome | 2001 |
93 other study(ies) available for arginine and Bleeding
| Article | Year |
|---|---|
High concentration of symmetric dimethylarginine is associated with low platelet reactivity and increased bleeding risk in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Arginine; Biomarkers; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors | 2022 |
Novel insight into Robert's cytoprotection: complex therapeutic effect of cytoprotective pentadecapeptide pentadecapeptide BPC 157 in rats with perforated stomach throughout modulation of nitric oxide-system. Comparison with L-arginine, ranitidine and pan
Topics: Animals; Arginine; Cytoprotection; Hemorrhage; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pantoprazole; Peptide Fragments; Proteins; Ranitidine; Rats; Rats, Wistar; Stomach Diseases | 2021 |
A Fibrinogen-Mimicking, Activated-Platelet-Sensitive Nanocoacervate Enhances Thrombus Targeting and Penetration of Tissue Plasminogen Activator for Effective Thrombolytic Therapy.
Topics: Animals; Arginine; Aspartic Acid; Chitosan; Fibrinogen; Fibrinolytic Agents; Glycine; Hemorrhage; Hemostatics; Mice; Oligopeptides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator | 2022 |
Therapy of the rat hemorrhagic cystitis induced by cyclophosphamide. Stable gastric pentadecapeptide BPC 157, L-arginine, L-NAME.
Topics: Animals; Anti-Ulcer Agents; Arginine; Cyclophosphamide; Cystitis; Female; Hemorrhage; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proteins; Rats; Rats, Wistar | 2019 |
Utilization and Outcomes of Children Treated with Direct Thrombin Inhibitors on Paracorporeal Ventricular Assist Device Support.
Topics: Adolescent; Antithrombins; Arginine; Child; Child, Preschool; Female; Heart-Assist Devices; Hemorrhage; Hirudins; Humans; Infant; Male; North America; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Stroke; Sulfonamides; Thrombosis; Treatment Outcome | 2020 |
[Complex management of type 2 heparin-induced thrombocytopenia in patients with major bleeding tendency: two case report].
Topics: 4-Hydroxycoumarins; Aged; Anticoagulants; Arginine; Blood Coagulation Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Hemorrhage; Heparin; Humans; Indenes; Intracranial Thrombosis; Male; Middle Aged; Neurosurgical Procedures; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Vitamin K | 2020 |
Treatment and outcomes of heparin-induced thrombocytopenia (HIT) in patients with neoplasm, a case series.
Topics: Aged; Anticoagulants; Arginine; Canada; Female; Fondaparinux; Gastrointestinal Neoplasms; Hematologic Neoplasms; Hemorrhage; Heparin; Humans; Male; Patient Acuity; Pipecolic Acids; Platelet Count; Retrospective Studies; Risk Adjustment; Sulfonamides; Thrombocytopenia | 2021 |
Importance of endothelial dysfunction biomarkers in patients with Crimean-Congo hemorrhagic fever.
Topics: Adult; Aged; Arginine; Biomarkers; Cytokines; Endothelin-1; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Hemorrhage; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Humans; Kinetics; Male; Middle Aged; Prognosis; Prospective Studies; ROC Curve; Thrombomodulin; Turkey; von Willebrand Factor | 2017 |
Argininosuccinate synthase 1 (ASS1): A marker of unclassified hepatocellular adenoma and high bleeding risk.
Topics: Adenoma, Liver Cell; Adult; Arginine; Argininosuccinate Synthase; Biomarkers, Tumor; Cohort Studies; Female; Hemorrhage; Humans; Laser Capture Microdissection; Liver; Liver Neoplasms; Mass Spectrometry; Middle Aged; Proteome | 2017 |
Tissue plasminogen activator mediates deleterious complement cascade activation in stroke.
Topics: Animals; Arginine; Benzhydryl Compounds; Brain; Brain Edema; Cell Death; Cells, Cultured; Complement C3; Endothelial Cells; Fibrinolysin; Hemoglobins; Hemorrhage; Humans; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Stroke; Tissue Plasminogen Activator | 2017 |
Use of Fondaparinux Off-Label or Approved Anticoagulants for Management of Heparin-Induced Thrombocytopenia.
Topics: Anticoagulants; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Factor Xa Inhibitors; Female; Fondaparinux; Hemorrhage; Heparin; Heparitin Sulfate; Hirudins; Hospital Mortality; Hospitalization; Humans; Male; Necrosis; Off-Label Use; Partial Thromboplastin Time; Patient Safety; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Registries; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thromboembolism; Treatment Outcome | 2017 |
A chemically-modified inactive antithrombin as a potent antagonist of fondaparinux and heparin anticoagulant activity.
Topics: Animals; Anticoagulants; Antithrombins; Arginine; Diacetyl; Drug Design; Female; Fondaparinux; Hemorrhage; Heparin; Heparin Antagonists; Humans; Mass Spectrometry; Mice; Partial Thromboplastin Time; Polysaccharides; Recombinant Proteins; Risk | 2013 |
Administration of human recombinant activated protein C is not associated with pancreatic parenchymal haemorrhage in L-arginine-induced experimental acute pancreatitis.
Topics: Acute Disease; Amylases; Animals; Anti-Infective Agents; Arginine; Hemorrhage; Humans; Injections, Intraperitoneal; Lipase; Male; Pancreas; Pancreatic Diseases; Pancreatitis; Protein C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Treatment Outcome | 2013 |
Intravenous warfarin and heparin-induced thrombocytopenia: making the diagnosis, management, modern monitoring, and multidisciplinary care.
Topics: Aged; Anticoagulants; Antithrombins; Arginine; Cardiac Surgical Procedures; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Male; Pipecolic Acids; Pulmonary Embolism; Sulfonamides; Thrombocytopenia; Thrombosis; Warfarin | 2014 |
Trends in parenteral direct thrombin inhibitor use in pediatric patients: analysis of a large administrative database.
Topics: Adolescent; Age Factors; Antithrombins; Arginine; Child; Child, Preschool; Databases, Factual; Female; Health Information Systems; Hemorrhage; Hirudins; Humans; Incidence; Infant; Infant, Newborn; Infusions, Parenteral; Male; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia; Young Adult | 2014 |
Efficacy and safety of argatroban and bivalirudine in patients with suspected heparin-induced thrombocytopenia.
Topics: Aged; Anticoagulants; Arginine; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia | 2015 |
Safety and economic considerations of argatroban use in critically ill patients: a retrospective analysis.
Topics: Adult; Aged; Anticoagulants; Arginine; Critical Illness; Dose-Response Relationship, Drug; Drug Costs; Female; Germany; Health Care Costs; Hemorrhage; Heparin; Humans; Intensive Care Units; Male; Middle Aged; Pipecolic Acids; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thromboembolism | 2015 |
Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine.
Topics: Amputation, Surgical; Animals; Anticoagulants; Arginine; Drug Evaluation, Preclinical; Hemorrhage; Hemostasis; Heparin; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proteins; Rats, Wistar; Thrombocytopenia; Warfarin | 2015 |
Novel oral anticoagulants and reversal agents: Considerations for clinical development.
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Cardiovascular Diseases; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Stroke | 2015 |
Comparison of bivalirudin to lepirudin and argatroban in patients with heparin-induced thrombocytopenia.
Topics: Aged; Anticoagulants; Antithrombins; Arginine; Dose-Response Relationship, Drug; Female; Hemorrhage; Heparin; Hirudins; Humans; International Normalized Ratio; Male; Middle Aged; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia | 2015 |
A new experimental rat model of pancreatitis using Ecballium elaterium.
Topics: Acute Disease; Amylases; Animals; Antioxidants; Arginine; Cucurbitaceae; Disease Models, Animal; Edema; Hemorrhage; Interleukin-1beta; Interleukin-6; Lung; Male; Malondialdehyde; Mice; Necrosis; Pancreas; Pancreatitis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2015 |
Outcomes of Argatroban Treatment in Patients With Atherothrombotic Stroke: Observational Nationwide Study in Japan.
Topics: Adult; Aged; Aged, 80 and over; Antithrombins; Arginine; Case-Control Studies; Cohort Studies; Female; Hemorrhage; Humans; Intracranial Arteriosclerosis; Intracranial Thrombosis; Japan; Male; Middle Aged; Odds Ratio; Pipecolic Acids; Practice Guidelines as Topic; Retrospective Studies; Stroke; Sulfonamides; Treatment Outcome | 2016 |
Reversal strategies for non-vitamin K antagonist oral anticoagulants: a critical appraisal of available evidence and recommendations for clinical management-a joint position paper of the European Society of Cardiology Working Group on Cardiovascular Pharm
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Consensus; Dabigatran; Evidence-Based Medicine; Factor Xa; Forecasting; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Risk Factors; Thrombosis; Vitamin K | 2017 |
[Antidotes for the new oral anticoagulants: Reality and expectations].
Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Coagulants; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Treatment Outcome | 2016 |
Mutation in a highly conserved glycine residue in strand 5B of plasminogen activator inhibitor 1 causes polymerisation.
Topics: Aged; Amino Acid Substitution; Animals; Arginine; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cytosine; DNA Mutational Analysis; Exons; Female; Genetic Predisposition to Disease; Glycine; Guanine; Hemorrhage; Hemostasis; Homozygote; Humans; Models, Molecular; Molecular Weight; Mutation; Phenotype; Plasminogen Activator Inhibitor 1; Polymerization; Protein Conformation; Structure-Activity Relationship; Transfection | 2017 |
What is the optimal anticoagulation level with argatroban during percutaneous coronary intervention?
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Female; Heart Diseases; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Retrospective Studies; Sulfonamides; Thrombocytopenia; Whole Blood Coagulation Time | 2008 |
Risk factors for major bleeding in patients with heparin-induced thrombocytopenia treated with argatroban: a retrospective study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Arginine; Blood Coagulation; Drug Monitoring; Female; Hemorrhage; Heparin; Humans; Lung Diseases; Male; Middle Aged; Odds Ratio; Partial Thromboplastin Time; Pipecolic Acids; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonamides; Thrombocytopenia; Thrombosis; Young Adult | 2008 |
Anticoagulation with the direct thrombin inhibitor argatroban in patients presenting with acute coronary syndromes.
Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Cardiac Catheterization; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Pipecolic Acids; Retrospective Studies; Risk Assessment; Sulfonamides; Thrombin; Treatment Outcome | 2009 |
Clinical investigation in ACS and PCI: shooting in the dark at a moving target.
Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Evidence-Based Medicine; Hemorrhage; Humans; Myocardial Infarction; Myocardial Revascularization; Pipecolic Acids; Research Design; Risk Assessment; Sulfonamides; Thrombin; Treatment Outcome | 2009 |
Pharmacokinetic and pharmacodynamic basis for effective argatroban dosing in pediatrics.
Topics: Adolescent; Arginine; Bilirubin; Body Weight; Child; Child, Preschool; Computer Simulation; Dose-Response Relationship, Drug; Female; Hemorrhage; Humans; Infant; Infant, Newborn; Male; Models, Biological; Partial Thromboplastin Time; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides | 2011 |
Safety and efficacy of the argatroban therapy during the early post-cardiac surgery period.
Topics: Aged; Aged, 80 and over; Arginine; Cardiac Surgical Procedures; Drug-Related Side Effects and Adverse Reactions; Female; Hemorrhage; Hospital Mortality; Humans; Male; Middle Aged; Pipecolic Acids; Postoperative Care; Postoperative Complications; Retrospective Studies; Sulfonamides; Thrombin; Thrombosis; Treatment Outcome | 2010 |
Venous limb gangrene and fatal hemorrhage: adverse consequences of HIT "overdiagnosis" in a patient with antiphospholipid syndrome.
Topics: Anticoagulants; Antiphospholipid Syndrome; Arginine; Diagnostic Errors; Drug Monitoring; Fatal Outcome; Female; Gangrene; Hemorrhage; Humans; Lung Diseases; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Upper Extremity; Vascular Diseases; Warfarin | 2011 |
Effects of argatroban as an anticoagulant for intermittent veno-venous hemofiltration (IVVH) in patients at high risk of bleeding.
Topics: Acute Kidney Injury; Anticoagulants; Arginine; Cohort Studies; Female; Follow-Up Studies; Hemofiltration; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Prognosis; Prospective Studies; Renal Replacement Therapy; Risk Factors; Sulfonamides; Survival Rate | 2011 |
Argatroban therapy in pediatric patients requiring nonheparin anticoagulation: an open-label, safety, efficacy, and pharmacokinetic study.
Topics: Anticoagulants; Arginine; Child; Child, Preschool; Female; Hemorrhage; Heparin; Humans; Infant; Liver Function Tests; Male; Pipecolic Acids; Platelet Aggregation Inhibitors; Prospective Studies; Sulfonamides; Survival Rate; Thrombocytopenia; Thrombosis; Tissue Distribution; Treatment Outcome | 2011 |
Implementation of an individualized argatroban protocol in an academic medical center.
Topics: Academic Medical Centers; Arginine; Clinical Protocols; Hemorrhage; Humans; Pipecolic Acids; Precision Medicine; Prothrombin Time; Retrospective Studies; Sulfonamides | 2011 |
The impact of L-NAME and L-arginine chronic toxicity induced lesions on ascites--pulmonary hypertension syndrome development in broiler chickens.
Topics: Animals; Arginine; Ascites; Chickens; Hemorrhage; Hypertension, Pulmonary; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Poultry Diseases; Toxicity Tests, Chronic | 2011 |
Recognition of heparin-induced thrombocytopenia and initiation of argatroban therapy after cardiothoracic surgery in the intensive care unit.
Topics: Antibodies; Anticoagulants; Arginine; Cardiac Surgical Procedures; Drug Substitution; Georgia; Hemorrhage; Heparin; Humans; Intensive Care Units; Pipecolic Acids; Platelet Factor 4; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonamides; Thoracic Surgical Procedures; Thrombocytopenia; Thrombosis; Time Factors; Treatment Outcome | 2012 |
The therapeutic management of bleeding and thrombotic disorders complicating CNS malignancies.
Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Bevacizumab; Central Nervous System Neoplasms; Fondaparinux; Glioblastoma; Glioma; Hemorrhage; Heparin, Low-Molecular-Weight; Hirudins; Humans; Pipecolic Acids; Polysaccharides; Postoperative Complications; Pulmonary Embolism; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Vena Cava Filters; Venous Thromboembolism; Venous Thrombosis; Warfarin | 2012 |
Safety and effectiveness outcomes of an inpatient collaborative drug therapy management service for direct thrombin inhibitors.
Topics: Adult; Aged; Antithrombins; Arginine; Cohort Studies; Cooperative Behavior; Drug Monitoring; Female; Hemorrhage; Heparin; Hirudins; Humans; Inpatients; Male; Medication Errors; Middle Aged; Outcome Assessment, Health Care; Partial Thromboplastin Time; Peptide Fragments; Pharmacists; Pharmacy Service, Hospital; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia; Time Factors | 2012 |
Biochemical and biological activities of the venom of a new species of pitviper from Vietnam, Triceratolepidophis sieversorum.
Topics: Animals; Arginine; Caseins; Cattle; Crotalid Venoms; Dose-Response Relationship, Drug; Esters; Female; Hemorrhage; Humans; Hydrolysis; Injections, Intraperitoneal; Kallikreins; Lethal Dose 50; Mice; Muscle, Skeletal; Phospholipases A; Skin; Species Specificity; Vietnam; Viperidae | 2003 |
Antithrombotic properties of a direct thrombin inhibitor with a prolonged half-life and AT-mediated factor Xa inhibitory activity.
Topics: Animals; Antithrombin III; Arginine; Blood Coagulation Tests; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Factor Xa Inhibitors; Fibrinolytic Agents; Fondaparinux; Half-Life; Hemorrhage; Heparin; Male; Molecular Structure; Oligosaccharides; Pipecolic Acids; Polysaccharides; Rabbits; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombolytic Therapy; Thrombosis | 2003 |
Involvement of nitric oxide and hyperbaric oxygen in the pathogenesis of cyclophosphamide induced hemorrhagic cystitis in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Arginine; Cyclophosphamide; Cystitis; Hemorrhage; Hyperbaric Oxygenation; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Urinary Bladder | 2003 |
Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats.
Topics: Animals; Antineoplastic Agents, Alkylating; Arginine; Cyclophosphamide; Cystitis; Disease Models, Animal; Enzyme Inhibitors; Female; Hemorrhage; Isothiuronium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley | 2004 |
L-arginine improves wound healing after trauma-hemorrhage by increasing collagen synthesis.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Collagen; Hemorrhage; Hydroxyproline; Male; Mice; Mice, Inbred C3H; Random Allocation; Transforming Growth Factor beta; Wound Healing; Wounds and Injuries | 2005 |
A comparison of lepirudin and argatroban outcomes.
Topics: Aged; Anticoagulants; Arginine; Female; Hemorrhage; Hirudins; Humans; Male; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin; Treatment Outcome | 2005 |
Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis.
Topics: Animals; Arginine; Base Sequence; DNA Primers; Gene Expression Regulation; Hemorrhage; Inflammation; Lung; Male; Nitric Oxide; Pancreatitis, Acute Necrotizing; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2005 |
Heparin-induced thrombocytopenia from venous thromboembolism treatment.
Topics: Amputation, Surgical; Anticoagulants; Arginine; Drug Administration Schedule; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Count; Randomized Controlled Trials as Topic; Recurrence; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thromboembolism; Treatment Outcome; Warfarin | 2005 |
Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats.
Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Hemorrhage; Injections, Spinal; Nitric Oxide; Oxadiazoles; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Sympathetic Nervous System | 2007 |
Antioxidants combined with NO donor enhance systemic inflammation in acute lung injury in rats.
Topics: Animals; Antioxidants; Arginine; Catalase; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Hemorrhage; Inflammation; Intestines; Male; Neutrophil Infiltration; Nitric Oxide Donors; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Distress Syndrome; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2007 |
Effect of body mass index on Argatroban therapy during percutaneous coronary intervention.
Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Blood Coagulation; Body Mass Index; Coronary Artery Disease; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Obesity; Pipecolic Acids; Retrospective Studies; Sulfonamides; Thrombocytopenia | 2008 |
Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT)--bridging the River Coumarin.
Topics: Acute Disease; Anticoagulants; Arginine; Blood Coagulation; Factor Xa Inhibitors; Fondaparinux; Hemorrhage; Heparin; Hirudins; Humans; International Normalized Ratio; Pipecolic Acids; Platelet Count; Polysaccharides; Recombinant Proteins; Research Design; Sulfonamides; Thrombin; Thrombocytopenia; Treatment Outcome; Venous Thrombosis; Warfarin | 2008 |
Alpha-defensin-like product and asymmetric dimethylarginine increase in mesenteric lymph after hemorrhage in anesthetized rat.
Topics: alpha-Defensins; Anesthesia; Animals; Antimicrobial Cationic Peptides; Arginine; Enzyme-Linked Immunosorbent Assay; Hemorrhage; Inflammation; Intestinal Mucosa; Lymph Nodes; Male; Phospholipases A2; Rats; Rats, Sprague-Dawley; Time Factors | 2008 |
Hemin arginate-induced heme oxygenase 1 expression improves liver microcirculation and mediates an anti-inflammatory cytokine response after hemorrhagic shock.
Topics: Animals; Anti-Inflammatory Agents; Arginine; Cytokines; Heat-Shock Proteins; Heme; Heme Oxygenase-1; Hemorrhage; Interleukin-10; Liver; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha | 2008 |
Hemorrhagic and proteolytic activities of Thailand snake venoms.
Topics: Animals; Arginine; Caseins; Hemorrhage; Injections, Subcutaneous; Mice; Peptide Hydrolases; Rabbits; Snakes; Thailand; Tyrosine; Venoms | 1967 |
Diminished effect of inhibition of nitric oxide synthase on regional cerebral vascular resistance in conscious and in isoflurane anesthetized rats during hemorrhage.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Brain; Hemorrhage; Isoflurane; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Vascular Resistance | 1993 |
The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat.
Topics: Acetylcholine; Adenosine Triphosphate; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Blood Pressure; Blood Transfusion; Brain; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Electroencephalography; Hemorrhage; Hypotension; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Organ Specificity; Parietal Lobe; Pituitary Gland; Regional Blood Flow; Spinal Cord; Vasodilator Agents | 1994 |
Nitric oxide contributes to multiorgan oxidative stress in acute experimental pancreatitis.
Topics: Acute Disease; Amylases; Animals; Arginine; Hemorrhage; Liver; Lung; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Wistar; Sulfhydryl Compounds | 1994 |
Influence of nitric oxide on the hemodynamic response to hemorrhage in conscious rabbits.
Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Blood Flow Velocity; Blood Pressure; Female; Heart Rate; Hemodynamics; Hemorrhage; Hindlimb; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Regional Blood Flow; Splanchnic Circulation; Time Factors | 1995 |
Evidence of a role for endothelium-derived nitric oxide in the regulation of vascular tone during acute haemorrhage.
Topics: Acute Disease; Animals; Arginine; Cats; Endothelium, Vascular; Enzyme Inhibitors; Hemorrhage; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vascular Resistance | 1995 |
Effect of inhibition of nitric oxide synthesis on the cardiovascular and endocrine responses to hemorrhage in conscious rabbits.
Topics: Animals; Arginine; Arginine Vasopressin; Baroreflex; Blood Pressure; Enzyme Inhibitors; Hemorrhage; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Renin | 1995 |
Viscoelastic behavior of "in situ" aortic wall during hemorrhagic hypotension.
Topics: Animals; Aorta; Arginine; Blood Pressure; Elasticity; Gases; Hemorrhage; Hydrogen-Ion Concentration; Hypotension; Indomethacin; Male; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Viscosity | 1995 |
Possible role for oxygen free radicals in the regulation of renal nitric oxide synthesis and blood flow.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Down-Regulation; Free Radicals; Hemorrhage; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen; Rats; Renal Circulation; Reperfusion Injury; Vasoconstriction | 1995 |
Disturbances in blood pressure homeostasis modify GABA release in the locus coeruleus.
Topics: Animals; Arginine; Blood Pressure; Blood Volume; gamma-Aminobutyric Acid; Hemorrhage; Homeostasis; Locus Coeruleus; Male; Neurons; Nitroprusside; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Taurine | 1994 |
Stroma-free hemoglobin increases blood pressure and GFR in the hypotensive rat: role of nitric oxide.
Topics: Animals; Arginine; Blood Gas Analysis; Blood Pressure; Blood Substitutes; Glomerular Filtration Rate; Hemoglobins; Hemorrhage; Hypotension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium | 1994 |
Nitric oxide inhibition causes intrauterine growth retardation and hind-limb disruptions in rats.
Topics: Amniotic Fluid; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Female; Fetal Diseases; Fetal Growth Retardation; Fetus; Hemorrhage; Hindlimb; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley | 1994 |
Influence of endothelium-derived relaxing factor on platelet function and hemostasis in vivo.
Topics: Animals; Arginine; Blood Platelets; Blood Pressure; Carbachol; Female; Hemoglobins; Hemorrhage; Hemostasis; Male; Nitric Oxide; Nitroarginine; Rabbits; Statistics as Topic | 1994 |
Requirements for neutrophil products and L-arginine in ischemia-reperfusion injury.
Topics: Animals; Arginine; Capillary Permeability; Complement Hemolytic Activity Assay; Hemorrhage; Hindlimb; Ischemia; Lung; Male; Muscles; Neutrophils; Peroxidase; Rats; Rats, Inbred Strains; Reperfusion Injury; Time Factors | 1993 |
L-Arginine reverses the abolition of hypovolaemic decompensation by N-nitro-L-arginine methyl ester and naloxone in conscious rabbits.
Topics: Animals; Arginine; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hemodynamics; Hemorrhage; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Shock, Hemorrhagic | 1995 |
Regional heterogeneity and differential vulnerability of cerebral and spinal vascular CO2-responsiveness during graded haemorrhagic hypotension.
Topics: Animals; Arginine; Blood Pressure; Blood Vessels; Carbon Dioxide; Cats; Cerebrovascular Circulation; Gases; Hemorrhage; Hypercapnia; Hypocapnia; Hypotension; Male; Reference Values; Spinal Cord | 1996 |
Antithrombotic and hemorrhagic effects of DX-9065a, a direct and selective factor Xa inhibitor: comparison with a direct thrombin inhibitor and antithrombin III-dependent anticoagulants.
Topics: Animals; Anticoagulants; Antithrombin III; Arginine; Bleeding Time; Blood Coagulation; Disease Models, Animal; Factor Xa Inhibitors; Hemorrhage; Heparin, Low-Molecular-Weight; Male; Naphthalenes; Peptide Hydrolases; Pipecolic Acids; Propionates; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombosis | 1997 |
Effect of a synthetic factor Xa inhibitor, YM-60828, on blood vessel patency in combination with a thrombolytic agent and on blood loss from the operation site in a rat model of arterial thrombosis.
Topics: Animals; Anticoagulants; Arginine; Blood Loss, Surgical; Carotid Arteries; Carotid Artery Thrombosis; Drug Evaluation, Preclinical; Hemorrhage; Heparin; Male; Naphthalenes; Pipecolic Acids; Piperidines; Rats; Recurrence; Reperfusion; Serine Proteinase Inhibitors; Sulfonamides; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator | 1998 |
Purification, cDNA cloning and molecular characteristic of a fibrinolytic enzyme from the venom of Agkistrodon acutus.
Topics: Agkistrodon; Amino Acid Sequence; Animals; Arginine; Base Sequence; Blotting, Western; Cloning, Molecular; Crotalid Venoms; DNA, Complementary; Escherichia coli; Hemorrhage; Male; Metalloendopeptidases; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid | 1998 |
L-arginine restores the depressed cardiac output and regional perfusion after trauma-hemorrhage.
Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Digestive System; Hemorrhage; Interleukin-6; Kidney; Laparotomy; Liver; Lung; Male; Mesentery; Muscle, Skeletal; Pancreas; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Resuscitation; Skin; Soft Tissue Injuries; Vascular Resistance | 1998 |
L-Arginine restores splenocyte functions after trauma and hemorrhage potentially by improving splenic blood flow.
Topics: Animals; Arginine; Cell Division; Cells, Cultured; Enzyme Inhibitors; Glucocorticoids; Guanidines; Hemorrhage; Interleukin-2; Male; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Spleen; Wounds and Injuries | 1999 |
Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.
Topics: Amino Acid Sequence; Animals; Arginine; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; Chlorides; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Glass; Hemorrhage; Heparin; Hirudin Therapy; Hirudins; Molecular Sequence Data; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Sulfonamides; Thrombin; Thrombosis; Vena Cava, Inferior; Venous Thrombosis | 1999 |
Prevention of the hemorrhagic hypotension-induced hepatic arterial vasoconstriction by L-arginine and naloxone.
Topics: Animals; Arginine; Cats; Drug Evaluation, Preclinical; Hemorrhage; Hypotension; Liver; Male; Naloxone; Nitroarginine; Regional Blood Flow; Vasoconstriction | 1999 |
Role of nitric oxide in regulation of renal sympathetic nerve activity during hemorrhage in conscious rats.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine; Blood Pressure; Consciousness; Enzyme Inhibitors; Heart Rate; Hemorrhage; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System | 1999 |
L-arginine attenuates trauma-hemorrhage-induced liver injury.
Topics: Animals; Arginine; Citrulline; Endothelium, Vascular; Glutathione Transferase; Hemodynamics; Hemorrhage; Immunity, Cellular; Liver; Male; Neutrophil Infiltration; Nitric Oxide; Ornithine; Prospective Studies; Rats; Rats, Sprague-Dawley; Resuscitation | 2000 |
Argatroban for treatment of heparin-induced thrombocytopenia.
Topics: Arginine; Health Expenditures; Hemorrhage; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis | 2001 |
The influence of L-arginine on heart rate and tissue oxygen extraction in haemorrhaged rabbits.
Topics: Acid-Base Equilibrium; Animals; Arginine; Blood Pressure; Blood Proteins; Heart Rate; Hematocrit; Hemoglobins; Hemorrhage; Monitoring, Physiologic; Oxygen; Rabbits; Stereoisomerism; Survival Rate; Water-Electrolyte Balance | 2001 |
The antithrombotic efficacy of AT-1459, a novel, direct thrombin inhibitor, in rat models of venous and arterial thrombosis.
Topics: Administration, Oral; Amidines; Animals; Arginine; Azepines; Bleeding Time; Carotid Artery Thrombosis; Dalteparin; Drug Evaluation, Preclinical; Fibrinolytic Agents; Hemorrhage; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Molecular Structure; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombin; Vena Cava, Inferior; Venous Thrombosis; Warfarin | 2001 |
Nitric oxide inhibition in rats improves blood pressure and renal function during hypovolemic shock.
Topics: Animals; Arginine; Blood Pressure; Glomerular Filtration Rate; Hemorrhage; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values; Renal Circulation; Shock; Vascular Resistance | 1991 |
Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat.
Topics: Animals; Arginine; Blood Cell Count; Blood Pressure; Blood Vessels; Capillary Permeability; Endotoxins; Hemorrhage; Intestinal Diseases; Iodine Radioisotopes; Jejunum; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains | 1990 |
Role of endothelium-derived nitric oxide in the bleeding tendency of uremia.
Topics: Animals; Arginine; Bleeding Time; Calcimycin; Endothelium, Vascular; Hemorrhage; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Adhesiveness; Platelet Aggregation; Rats; Rats, Inbred Strains; Uremia | 1990 |
Relationship between pharmacological actions and enzymatic activities of the venom of Trimeresurus gramineus.
Topics: Animals; Antivenins; Arginine; Bradykinin; Capillary Permeability; Caseins; Cysteine; Diaphragm; Edetic Acid; Electrophoresis; Enzymes; Esterases; Eye; Hemorrhage; Histamine Release; Hot Temperature; Mice; Phospholipases; Rabbits; Rats; Snakes; Thrombin; Venoms | 1970 |
Hypophysectomy in diabetic retinopathy. The relationship between the degree of pituitary ablation and ocular response.
Topics: Adolescent; Adult; Arginine; Blood Glucose; Cryosurgery; Diabetes Mellitus; Diabetic Retinopathy; Female; Fundus Oculi; Growth Hormone; Hemorrhage; Humans; Hypophysectomy; Insulin; Male; Microsurgery; Middle Aged; Pituitary Function Tests; Pituitary Gland; Postoperative Complications; Retinal Hemorrhage; Stereotaxic Techniques; Visual Acuity; Vitreous Body | 1974 |
Observations on the release and clearance of neurophysin and the neurohypophysial hormones in the rat.
Topics: Animals; Arginine; Biological Assay; Calcium Chloride; Cross Reactions; Half-Life; Hemorrhage; Hypophysectomy; Iodine Isotopes; Male; Neurophysins; Oxytocin; Radioimmunoassay; Rats; Vasopressins | 1973 |
Pituitary apoplexy in acromegaly.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adult; Arginine; Blood; Blood Glucose; Diabetes Complications; Female; Glucose Tolerance Test; Growth Hormone; Hemorrhage; Humans; Hydrocortisone; Insulin; Islets of Langerhans; Necrosis; Osmolar Concentration; Pituitary Diseases; Thyroxine; Tolbutamide; Urine | 1968 |
Neutralization of Vipera palestinae hemorrhagin by antibody fragments.
Topics: Alkylation; Animals; Antibodies; Antigen-Antibody Reactions; Arginine; Esterases; Esters; Hemorrhage; Immunoglobulin G; Immunoglobulins; Neutralization Tests; Oxidation-Reduction; Papain; Pepsin A; Peptide Hydrolases; Rabbits; Snakes; Sulfonic Acids; Toluene; Venoms | 1971 |
The effect of hydration on vasopressin and neurophysin release in the rat.
Topics: Animals; Arginine; Biological Assay; Hemorrhage; Male; Osmolar Concentration; Pituitary Hormones, Posterior; Radioimmunoassay; Rats; Sodium Chloride; Vasopressins; Water; Water Deprivation; Water Intoxication; Water-Electrolyte Balance | 1971 |
[Cross circulation experiments with unanesthetized rats. 3. Clearance and volume of distribution of exogenous and endogenous ADH].
Topics: Animals; Arginine; Hemorrhage; Metabolic Clearance Rate; Parabiosis; Rats; Time Factors; Vasopressins | 1969 |
The effect of acute extracellular fluid volume expansion and acute haemorrhage on plasma antidiuretic hormone and oxytocin levels in dogs.
Topics: Animals; Arginine; Body Fluids; Dogs; Extracellular Space; Hemorrhage; Natriuresis; Oxytocin; Vasopressins | 1968 |
The release, clearance and plasma protein binding of oxytocin in the anaesthetized rat.
Topics: Anesthesia; Animals; Arginine; Blood Proteins; Female; Hemorrhage; Kidney; Metabolic Clearance Rate; Oxytocin; Pentobarbital; Pressure; Protein Binding; Rats; Temperature; Time Factors; Vasopressins | 1969 |