arginine and Bleeding

arginine has been researched along with Bleeding in 146 studies

Research

Studies (146)

TimeframeStudies, this research(%)All Research%
pre-199011 (7.53)18.7374
1990's31 (21.23)18.2507
2000's35 (23.97)29.6817
2010's59 (40.41)24.3611
2020's10 (6.85)2.80

Authors

AuthorsStudies
Dizdarevic, AM; Eyileten, C; Gasecka, A; Jarosz-Popek, J; Lang, IM; Nowak, A; Postula, M; Siller-Matula, JM; Ufnal, M; Wolska, M1
Bilic, Z; Boban Blagaic, A; Brizic, I; Drmic, D; Gojkovic, S; Hriberski, K; Kalogjera, L; Kasnik, K; Knezevic, M; Kokot, A; Kralj, T; Krezic, I; Kubat, M; Lojo, N; Malekinusic, D; Milavic, M; Peklic, M; Seiwerth, S; Sever, M; Sikiric, P; Sikiric, S; Siroglavic, M; Skorak, I; Skrtic, A; Tvrdeic, A; Vladic, J; Vukojevic, J1
Chen, HS; Cui, Y; Hou, XW; Li, XQ; Tian, XF; Wang, XH; Zhou, ZH1
Chen, R; Guo, Y; Huang, Y; Jiang, J; Li, Y; Ren, J; Zhao, Q; Zhou, J1
Jung, C; Leentjens, J; Middeldorp, S1
Blagaic, AB; Drmic, D; Halle, ZB; Jandric, I; Kokot, A; Luetic, K; Seiwerth, RS; Seiwerth, S; Sever, AZ; Sikiric, P; Strinic, D; Sucic, M; Vuletic, LB; Zoricic, I1
Bhatt, SH; Dobesh, PP; Glaubius, K; Trujillo, TC1
Gulseth, MP; Kaide, CG1
Boyle, G; Buchholz, H; Cantor, RS; Conway, J; Fynn-Thompson, F; Griffiths, E; Hawkins, B; Lorts, A; Lytrivi, ID; Machado, D; May, L; Niebler, RA; Rossano, J; Sutcliffe, DL; VanderPluym, CJ1
Ansell, J; Baker, C; Bakhru, SH; Burnett, A; Chen, L; Jiang, X; Laulicht, BE; Steiner, S; Villano, S1
Bergis, B; Chanson, N; Chassin, O; Drouot, S; Gleizes, O; Legris, N; Proulle, V; Ract, C; Walle, EM; Werner, M1
Lai, CMB; Lee, AYY; Smith, T1
Gkiatas, I; Korompilias, AV; Kostas-Agnantis, I; Papadopoulos, DV; Tsantes, AG; Ziara, P1
Arslan, M; Karahan, SC; Koksal, I; Mentese, A; Yilmaz, G; Yilmaz, H1
Abou Hammoud, A; Balabaud, C; Bioulac-Sage, P; Blanc, JF; Dartigues, B; Dugot-Senant, N; Dupuy, JW; Ezzoukry, Z; Henriet, E; Le Bail, B; Leste-Lasserre, T; Nikolski, M; Pallares-Lupon, N; Raymond, AA; Saltel, F1
Fischer, AM; Godier, A; Martin, AC; Mauge, L; Smadja, DM1
Ahmad, S; Ducruet, AF; Larkin, TM; Lauver, MA; Zhao, XJ1
Almegren, M1
Banik, N; Beyer-Westendorf, J; Brachmann, J; Dohmen, PM; Eberle, S; Hankowitz, J; Klamroth, R; Kropff, S; Lindhoff-Last, E; Madlener, K; Müller, MM; Pötzsch, B; Schellong, S; Schindewolf, M; Steindl, J1
Douketis, J; Levy, JH; Weitz, JI1
Gheysens, O; Goffin, KE; Hoylaerts, MF; Jacquemin, M; Liesenborghs, L; Peerlinck, K; Peetermans, M; Peetermans, WE; Vanassche, T; Verhaegen, J; Verhamme, P; Wijngaerden, EV1
Bianchini, EP; Borgel, D; Fazavana, J; Picard, V; Saller, F; Smadja, C; Taverna, M1
Pötzsch, B1
Babu, BI; Jamdar, S; Jeziorska, M; McMahon, RF; Nirmalan, M; Siriwardena, AK1
Burger, CF; Schlesinger, JJ1
Cao, FF; Feng, X; Jiao, RN; Zhang, HT1
Moffett, BS; Teruya, J1
Bahlmann, A; Beiderlinden, M; Brezina, T; Geib, J; Golla, E; Greinacher, A; Kienbaum, P; Kindgen-Milles, D; Pannen, B; Schaefer, MS; Treschan, TA; Werner, P1
Lin, JK; Tong, LM; Vo, QA1
Baumgarten, G; Boehm, O; Graeff, I; Hoeft, A; Kim, SC; Schewe, JC; Tran, N; Wittmann, M1
Bojic, D; Drmic, D; Hrelec Patrlj, M; Kokot, A; Kolenc, D; Radic, B; Seiwerth, S; Sikiric, P; Stupnisek, M; Suran, J; Vcev, A; Zenko Sever, A1
Berkowitz, SD; Costin', J; Curnutte, JT; Gibson, CM; Hoffman, M; Kaminskas, E; Kowey, PR; Krucoff, MW; Levy, JH; Mintz, PD; Reilly, PA; Sager, PT; Sarich, TC; Seltzer, JH; Singer, DE; Stockbridge, N; Weitz, JI1
Crowther, M; Crowther, MA1
Bain, J; Meyer, A1
Arslan, S; Basuguy, E; Bozdag, Z; Ibiloglu, I; Kaplan, I; Okur, MH; Turkoglu, A; Uluca, U; Zeytun, H1
Cuker, A; Siegal, D1
Fushimi, K; Horiguchi, H; Matsubara, T; Nakajima, S; Wada, T; Yahagi, N; Yasunaga, H1
Agewall, S; Atar, D; Drexel, H; Husted, SE; Kaski, JC; Kjeldsen, K; Koller, L; Lewis, BS; Lip, GYH; Morais, J; Niessner, A; Storey, RF; Tamargo, J; Torp-Pedersen, C; Verheugt, FWA; Wassmann, S1
Gómez-Outes, A; Lecumberri, R1
Ageno, W; Chan, NC; Crowther, M; Levy, JH; Verhamme, P; Weitz, JI1
Asirvatham, SJ; Hu, TY; Vaidya, VR1
Fanikos, J; Smythe, MA; Trujillo, T1
Hussain, SS; Mukherjee, D; Tyroch, AH1
Antman, EM; Giugliano, RP; Ruff, CT1
Fanikos, J; Huisman, MV2
Levy, JH2
Kaatz, S; Milling, TJ2
Baumgarten, G; Kim, S; Koster, A; Riedel, R; Schewe, JC; Schmieder, A1
Bhagirath, VC; Eikelboom, JW; Monagle, S; Ng, KH1
Iwaki, T; Kanayama, N; Nagahashi, K; Suzuki-Inoue, K; Takano, K; Umemura, K; Urano, T1
Desborough, MJ; Shapiro, S; Zhang, XY1
Baron, SJ; Cruz-Gonzalez, I; Healy, JL; Jang, IK; Osakabe, M; Sanchez-Ledesma, M; Watanabe, H; Yeh, RW1
Hursting, MJ; Verme-Gibboney, CN1
Baron, SJ; Cruz-Gonzalez, I; Healy, JL; Jang, IK; McNulty, IA; Pomerantsev, E; Yeh, RW1
Dangas, G1
Jianping, N; Siyuan, D; Yanchao, L; Yixiong, Z1
Buerke, M; Desaga, M; Genth-Zotz, S; Gulba, DC; Harder, S; Heyndrickx, GR; Rau, M; Rössig, L; Schneider, T; Zeiher, AM1
Boyle, DA; Choi, YM; Cox, DS; Gobburu, JV; Hossain, M; Madabushi, R; Patel, BR; Young, G1
Agnihotri, AK; Hoffman, WD; Jang, IK; Nam, KH; Yeh, RW; Yoon, JH1
Bandyk, DF; Bartholomew, JR; Boyce, SW; Frame, JN; Rice, L1
Smythe, MA; Warkentin, TE; Woodhouse, AL; Zakalik, D1
Chen, X; Chen, Y; Ma, Z; Sun, X; Wang, Y; Xiang, J; Xiao, Q; Zhou, J1
Boshkov, LK; Boyle, DA; Cox, DS; Hursting, MJ; Kallender, H; Raffini, LJ; Soffer, J; Sullivan, JE; Tarka, EA; Young, G1
Bradley, AM; Branan, T1
Artuković, B; Cenan, S; Cooper, RG; Dinarina-Sablić, M; Dzaja, P; Grabarević, Z; Tisljar, M; Zelenika, TA1
Demma, LJ; Levy, JH; Paciullo, CA1
Doepker, B; Gerlach, AT; Mount, KL; Murphy, CV; Philips, GS; Ryder, LJ1
Knovich, MA; Lesser, GJ; Strowd, RE1
Cooper, T; Kokko, H; Mazur, J; Taber, D; Uber, WE; White, CL1
Mizuno, Y; Noda, K; Tanaka, R; Urabe, T1
Herrmann, HW; Kuch, U; Mebs, D; Ziegler, T1
Buijsman, R; Meuleman, DG; Princen, AW; Smit, MJ; Van Dinther, TG; Vogel, GM1
DAVIDSON, CS1
Bilgic, H; Deveci, S; Korkmaz, A; Oter, S; Ozgurtas, T; Sadir, S; Topal, T1
Bilgic, H; Korkmaz, A; Oter, S; Oztas, E; Topal, T; Yildirim, I1
Bartholomew, JR; Hursting, MJ1
Angele, MK; Angele, P; Chaudry, IH; Hernandez-Richter, T; Jauch, KW; Mayr, S; Prix, N; van den Engel, NK; Wichmann, MW; Wittmann, F1
McIntosh, BA1
Koerber, JM; Mattson, JC; Smythe, MA; Stephens, JL1
Katz, E; Kim, KY; McNulty, I1
Chen, Y; Guo, XJ; Wang, CY; Wang, L; Wu, HS; Xu, JB; Zhang, JH; Zhang, L1
Aghababian, RV; Begelman, SM; Hursting, MJ; McCollum, D1
Hursting, MJ; Lewis, BE1
Arnolda, LF; Holobotovskyy, VV; Malik, V; McKitrick, DJ; Phillips, JK1
Fischer, KG1
Beiderlinden, M; Görlinger, K; Peters, J; Treschan, TA1
Kääpä, P; Kiss, J; Savunen, T1
Hursting, MJ; Jang, IK1
Ahmed, I; Majeed, A; Powell, R1
Lepor, NE1
Warkentin, TE1
Asher, LV; Atkins, JL; Gorbunov, NV; Hammamieh, R; Jett, M; Kiang, JG1
Bauer, I; Heiser, J; Kubulus, D; Mathes, A; Pavlidis, D; Pradarutti, S; Raddatz, A; Rensing, H; Wolf, B1
Ganthavorn, S; Toom, PM; Tu, AT1
Chi, OZ; Sinha, AK; Wei, HM; Weiss, HR1
Moncada, S; Radomski, MW1
Balla, I; Dawson, TM; Kovách, AG; Lohinai, Z; Marczis, J; Snyder, SH1
Dabrowski, A; Gabryelewicz, A1
Hasser, EM; Koch, MA; Schadt, JC1
Ekelund, U; Mellander, S1
Chiu, T; Reid, IA1
Krieger, EM; Xavier-Neto, J1
Castaneda, A; Hernandez, R; Myers, SI1
Philippu, A; Schneider, C; Singewald, N1
Lieberthal, W; McGarry, AE; Thompson, A; Valeri, CR1
Clark, DA; Diket, AL; Eloby-Childress, S; Greenberg, SS; Miller, MJ; Munshi, UK; Pierce, MR; Voelker, CA; Zhang, XJ1
Buchanan, MR; Houston, DS1
Mulligan, MS; Seekamp, A; Till, GO; Ward, PA1
Ludbrook, J; Ventura, S1
Verstraete, M1
Greenberg, JH; Jaggi, JL; Komjáti, K; Kovách, AG; Nyáry, I; Reivich, M; Sándor, P1
Hara, T; Kunitada, S; Morishima, Y; Tanabe, K; Terada, Y1
Hirayama, F; Kawasaki, T; Koshio, H; Matsumoto, Y; Sato, K; Taniuchi, Y1
Du, XY; Jin, Y; Pan, H; Wu, XF; Zhou, YC; Zhu, H1
Angele, MK; Bland, KI; Chaudry, IH; Cioffi, WG; Smail, N; Wang, P1
Angele, MK; Ayala, A; Chaudry, IH; Cioffi, WG; Knöferl, MW; Smail, N1
Fukazawa, T; Goto, Y; Hayashi, H; Inoue, Y; Komatsu, Y1
Benyó, Z; Kovách, AG; Sándor, P; Szabó, C1
Jang, IK; Januzzi, JL1
Abe, Y; Fujisawa, Y; Miyanaka, H; Miyatake, A; Mori, N; Yube, K1
Noris, M; Remuzzi, G1
Ahmad, S; Ahsan, A; Fareed, J; Hoppensteadt, DA; Iqbal, O; Lewis, BE; Walenga, JM1
Angele, MK; Ayala, A; Chaudry, IH; Fitzal, F; Knöferl, MW; Schwacha, MG; Smail, N; Wang, P1
Besse, P; Darius, H; Fels, PW; Fitzgerald, D; Garrigou, D; Müller, E; Puel, J; Simoons, ML; Vahanian, A; Van de Werf, F; Vermeer, F1
Bartholomew, J; Berkowitz, SD; Fareed, J; Hursting, MJ; Jang, IK; Kelton, JG; Lerner, RG; Lewis, BE; Matthai, WH; Moran, J; Rifkin, SD; Rustagi, PK; Sham, R; Walenga, JM; Wallis, DE; Zeigler, ZR1
Prostran, M; Todorović, Z; Vucković, S1
Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H1
Corno, A; Horisberger, J; Marty, B; Mueller, X; von Segesser, LK1
Cho, JH; Dan, T; Kim, HY; Koga, T; Koo, BA; Seo, HS; Yun, CH1
Lieberthal, W; McGarry, AE; Sheils, J; Valeri, CR1
Boughton-Smith, NK; Hutcheson, IR; Whittle, BJ1
Corna, D; Macconi, D; Perico, N; Remuzzi, G; Viganò, G; Zoja, C1
Ouyang, C; Shiau, SY1
Adams, DA; Dashe, AM; Gipstein, RM; Heuser, G; Rand, RW; Roth, NH1
Burton, AM; Forsling, ML; Martin, MJ; Sturdy, JC1
Field, JB; Finster, JL; Mintz, DH; Raskin, P; Taylor, AL1
de Vries, A; Hahn, J; Moroz, C1
Burton, AM; Forsling, ML; Martin, MJ1
Aziz, O1
De Wardener, HE; Fabian, M; Jones, JJ; Lee, J; Schrier, RW; Verroust, PJ1
Fabian, M; Forsling, ML; Jones, JJ; Lee, J1

Reviews

38 review(s) available for arginine and Bleeding

ArticleYear
A short review of ciraparantag in perspective of the currently available anticoagulant reversal agents.
    Drug discovery today, 2022, Volume: 27, Issue:10

    Topics: Administration, Oral; Anticoagulant Reversal Agents; Anticoagulants; Anticoagulation Reversal; Antidotes; Arginine; Hemorrhage; Heparin; Humans; Piperazines; Recombinant Proteins

2022
Antidotes for reversal of direct oral anticoagulants.
    Pharmacology & therapeutics, 2019, Volume: 204

    Topics: Animals; Antibodies, Monoclonal, Humanized; Arginine; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins

2019
Current Strategies for the Management of Bleeding Associated with Direct Oral Anticoagulants and a Review of Investigational Reversal Agents.
    The Journal of emergency medicine, 2020, Volume: 58, Issue:2

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Factors; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Practice Guidelines as Topic; Recombinant Proteins

2020
The role of new oral anticoagulants in orthopaedics: an update of recent evidence.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2017, Volume: 27, Issue:5

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Tests; Dabigatran; Factor Xa; Hemorrhage; Humans; Orthopedic Procedures; Piperazines; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles; Venous Thromboembolism

2017
[State of the art: Direct oral anticoagulants and transfusion].
    Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine, 2017, Volume: 24, Issue:3

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Antidotes; Antithrombins; Arginine; Blood Coagulation Factors; Blood Transfusion; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hemostatics; Humans; Piperazines; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Stroke; Thrombophilia

2017
Reversal of direct oral anticoagulants.
    Vascular health and risk management, 2017, Volume: 13

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation; Coagulants; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Risk Factors; Treatment Outcome

2017
Reversal agents for non-vitamin K antagonist oral anticoagulants.
    Nature reviews. Cardiology, 2018, Volume: 15, Issue:5

    Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Blood Loss, Surgical; Coagulants; Factor Xa; Hemorrhage; Humans; Perioperative Care; Piperazines; Postoperative Hemorrhage; Recombinant Proteins; Risk Assessment; Risk Factors; Treatment Outcome

2018
Argatroban: for a few selected patients.
    Prescrire international, 2013, Volume: 22, Issue:135

    Topics: Anticoagulants; Antithrombins; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Drug Interactions; Drug Substitution; Hemorrhage; Heparin; Heparitin Sulfate; Humans; Patient Selection; Pipecolic Acids; Risk Assessment; Risk Factors; Sulfonamides; Thrombocytopenia; Treatment Outcome; Venous Thrombosis

2013
[Anticoagulation].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2013, Volume: 108, Issue:4

    Topics: Administration, Oral; Anticoagulants; Antithrombins; Arginine; Arrhythmias, Cardiac; Blood Coagulation Tests; Factor Xa Inhibitors; Hemorrhage; Heparin; Heparinoids; Hirudins; Humans; Infusions, Intravenous; Orthopedic Procedures; Peptide Fragments; Pipecolic Acids; Postoperative Complications; Pulmonary Embolism; Recombinant Proteins; Risk Factors; Secondary Prevention; Sulfonamides; Thromboembolism; Treatment Outcome; Venous Thrombosis; Vitamin K

2013
[Meta-analysis of the role of Argatroban in renal replacement therapy].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2013, Volume: 35, Issue:6

    Topics: Antithrombins; Arginine; Hemorrhage; Humans; Incidence; Pipecolic Acids; Renal Dialysis; Renal Insufficiency; Renal Replacement Therapy; Sulfonamides; Thrombosis

2013
Antidotes for novel oral anticoagulants: current status and future potential.
    Arteriosclerosis, thrombosis, and vascular biology, 2015, Volume: 35, Issue:8

    Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Coagulants; Hemorrhage; Humans; Piperazines; Risk Assessment; Risk Factors; Treatment Outcome

2015
Monitoring and reversal of direct oral anticoagulants.
    Hematology. American Society of Hematology. Education Program, 2015, Volume: 2015

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Factors; Blood Coagulation Tests; Dabigatran; Factor VIIa; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hemostasis; Humans; Partial Thromboplastin Time; Piperazines; Prothrombin; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles; Thrombin Time

2015
When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH.
    Journal of thrombosis and haemostasis : JTH, 2016, Volume: 14, Issue:3

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Coagulants; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins

2016
Reversing anticoagulant effects of novel oral anticoagulants: role of ciraparantag, andexanet alfa, and idarucizumab.
    Vascular health and risk management, 2016, Volume: 12

    Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Blood Coagulation; Blood Coagulation Tests; Coagulants; Drug Monitoring; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins

2016
Reversal agents for use with direct and indirect anticoagulants.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2016, May-15, Volume: 73, Issue:10 Suppl 2

    Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins

2016
Reversal of Newer Direct Oral Anticoagulant Drugs (DOACs).
    Cardiovascular & hematological agents in medicinal chemistry, 2017, Volume: 14, Issue:2

    Topics: Administration, Oral; Animals; Antibodies, Monoclonal, Humanized; Anticoagulants; Antifibrinolytic Agents; Arginine; Blood Coagulation; Blood Coagulation Factors; Cardiovascular Diseases; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Models, Molecular; Piperazines; Recombinant Proteins

2017
Management of Bleeding With Non-Vitamin K Antagonist Oral Anticoagulants in the Era of Specific Reversal Agents.
    Circulation, 2016, Jul-19, Volume: 134, Issue:3

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Antithrombins; Arginine; Blood Coagulation Factors; Dabigatran; Factor VIIa; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hemostatics; Humans; Piperazines; Plasma; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles

2016
Idarucizumab and Factor Xa Reversal Agents: Role in Hospital Guidelines and Protocols.
    The American journal of medicine, 2016, Volume: 129, Issue:11S

    Topics: Antibodies, Monoclonal, Humanized; Antidotes; Antithrombins; Arginine; Blood Coagulation Factors; Clinical Protocols; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hospitals; Humans; Piperazines; Practice Guidelines as Topic; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban

2016
Discontinuation and Management of Direct-Acting Anticoagulants for Emergency Procedures.
    The American journal of medicine, 2016, Volume: 129, Issue:11S

    Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Antithrombins; Arginine; Dabigatran; Deprescriptions; Emergencies; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Humans; International Normalized Ratio; Piperazines; Prothrombin Time; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Surgical Procedures, Operative

2016
Preclinical and Clinical Data for Factor Xa and "Universal" Reversal Agents.
    The American journal of medicine, 2016, Volume: 129, Issue:11S

    Topics: Animals; Antidotes; Arginine; Atrial Fibrillation; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Pyrazoles; Pyridones; Recombinant Proteins; Rivaroxaban; Stroke; Thromboembolism

2016
Idarucizumab and factor Xa reversal agents: role in hospital guidelines and protocols.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:11S

    Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Clinical Protocols; Dabigatran; Emergency Treatment; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Hospitals; Humans; Patient Selection; Piperazines; Practice Guidelines as Topic; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Surgical Procedures, Operative; Thiazoles

2016
Discontinuation and management of direct-acting anticoagulants for emergency procedures.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:11S

    Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Blood Coagulation Tests; Emergency Treatment; Factor Xa; Hemorrhage; Humans; Perioperative Care; Piperazines; Recombinant Proteins; Withholding Treatment

2016
Preclinical and clinical data for factor Xa and "universal" reversal agents.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:11S

    Topics: Animals; Anticoagulants; Arginine; Clinical Trials as Topic; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins

2016
[Heparin-induced thrombocytopenia type II (HIT II) : A medical-economic view].
    Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2017, Volume: 112, Issue:4

    Topics: Arginine; Chondroitin Sulfates; Costs and Cost Analysis; Dermatan Sulfate; Germany; Hemorrhage; Heparin; Heparitin Sulfate; Hospitalization; Humans; Pipecolic Acids; Risk Factors; Sulfonamides; Thrombocytopenia; Thrombosis; Treatment Outcome

2017
Clinical implications of reversal agents for direct oral anticoagulants.
    Future cardiology, 2017, Volume: 13, Issue:2

    Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Antithrombins; Arginine; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Pyrazoles; Pyridines; Pyridones; Recombinant Proteins; Rivaroxaban; Thiazoles; Venous Thromboembolism

2017
Reversal of direct oral anticoagulants.
    British journal of hospital medicine (London, England : 2005), 2017, Mar-02, Volume: 78, Issue:3

    Topics: Aged; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Antithrombins; Arginine; Blood Coagulation Factors; Coagulants; Dabigatran; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Intracranial Hemorrhages; Male; Partial Thromboplastin Time; Piperazines; Prothrombin Time; Recombinant Proteins; Thrombin Time

2017
HEPATIC COMA.
    Disease-a-month : DM, 1964, Volume: 45

    Topics: Ammonia; Anti-Bacterial Agents; Arginine; Blood; Diagnosis; Diagnosis, Differential; Diuretics; Gastrointestinal Hemorrhage; Glutamates; Hemorrhage; Hepatic Encephalopathy; Humans; Hypnotics and Sedatives; Metabolism; Pathology; Surgical Procedures, Operative; Toxicology; Water-Electrolyte Balance

1964
Developing an algorithm for treating heparin-induced thrombocytopenia.
    Clinical advances in hematology & oncology : H&O, 2004, Volume: 2, Issue:4

    Topics: Algorithms; Anticoagulants; Antigen-Antibody Complex; Arginine; Clinical Trials as Topic; Diagnosis, Differential; Disease Management; Follow-Up Studies; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Immunoglobulin G; Pipecolic Acids; Platelet Activation; Platelet Count; Platelet Factor 4; Prognosis; Purpura, Thrombocytopenic, Idiopathic; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombophilia; Time Factors

2004
Direct thrombin inhibition during percutaneous coronary intervention in patients with heparin-induced thrombocytopenia.
    Expert review of cardiovascular therapy, 2007, Volume: 5, Issue:1

    Topics: Angioplasty, Balloon, Coronary; Antithrombins; Arginine; Drug Interactions; Economics, Pharmaceutical; Fibrinolytic Agents; Hemorrhage; Heparin; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Platelet Aggregation Inhibitors; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Thrombosis

2007
Essentials of anticoagulation in hemodialysis.
    Hemodialysis international. International Symposium on Home Hemodialysis, 2007, Volume: 11, Issue:2

    Topics: Anticoagulants; Arginine; Blood Coagulation; Chondroitin Sulfates; Dermatan Sulfate; Equipment Failure; Hemorrhage; Heparin; Heparitin Sulfate; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Renal Dialysis; Renal Insufficiency, Chronic; Sulfonamides

2007
Heparin induced thrombocytopenia: diagnosis and management update.
    Postgraduate medical journal, 2007, Volume: 83, Issue:983

    Topics: Anticoagulants; Arginine; Cardiovascular Surgical Procedures; Chondroitin Sulfates; Dermatan Sulfate; Fibrinolytic Agents; Hemorrhage; Heparin; Heparitin Sulfate; Hirudins; Humans; Pipecolic Acids; Recombinant Proteins; Renal Dialysis; Sulfonamides; Thrombocytopenia; Warfarin

2007
Anticoagulation for acute coronary syndromes: from heparin to direct thrombin inhibitors.
    Reviews in cardiovascular medicine, 2007, Volume: 8 Suppl 3

    Topics: Acute Disease; Angina Pectoris; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Fondaparinux; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudins; Humans; Models, Molecular; Molecular Structure; Myocardial Ischemia; Peptide Fragments; Pipecolic Acids; Platelet Activation; Polysaccharides; Recombinant Proteins; Sulfonamides; Syndrome; Thrombin; Thrombosis

2007
The biological and pharmacological role of nitric oxide in platelet function.
    Advances in experimental medicine and biology, 1993, Volume: 344

    Topics: Amino Acid Oxidoreductases; Arginine; Arteriosclerosis; Blood Platelets; Endothelium, Vascular; Enzyme Induction; Guanylate Cyclase; Hemorrhage; Hemostasis; Humans; Iron-Sulfur Proteins; Isoenzymes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Platelet Activation; Platelet Aggregation; Thrombosis; Vasodilation

1993
Direct thrombin inhibitors: appraisal of the antithrombotic/hemorrhagic balance.
    Thrombosis and haemostasis, 1997, Volume: 78, Issue:1

    Topics: Antithrombins; Arginine; Clinical Trials, Phase III as Topic; Fibrinolytic Agents; Hemorrhage; Hirudin Therapy; Hirudins; Humans; Myocardial Infarction; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Sulfonamides

1997
Heparin induced thrombocytopenia: diagnosis and contemporary antithrombin management.
    Journal of thrombosis and thrombolysis, 1999, Volume: 7, Issue:3

    Topics: Ancrod; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Drug Combinations; Fibrinolytic Agents; Forecasting; Gangrene; Hemorrhage; Heparin; Heparitin Sulfate; Hirudin Therapy; Hirudins; Humans; Pipecolic Acids; Platelet Aggregation; Protein C; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Warfarin

1999
Uremic bleeding: closing the circle after 30 years of controversies?
    Blood, 1999, Oct-15, Volume: 94, Issue:8

    Topics: Anemia; Animals; Arginine; Bleeding Time; Blood Platelets; Endothelium, Vascular; Enzyme Inhibitors; Erythropoietin; Guanidines; Hemorrhage; History, 18th Century; History, 20th Century; Humans; Isoenzymes; Kidney Failure, Chronic; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; omega-N-Methylarginine; Rats; Succinates; Uremia

1999
Anticoagulation: the present and future.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:3

    Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis

2001
Alternatives to unfractionated heparin for anticoagulation in cardiopulmonary bypass.
    Perfusion, 2001, Volume: 16, Issue:5

    Topics: Abciximab; Ancrod; Antibodies, Monoclonal; Anticoagulants; Arginine; Cardiopulmonary Bypass; Chondroitin Sulfates; Cross Reactions; Dermatan Sulfate; Drug Combinations; Drug Hypersensitivity; Factor Xa Inhibitors; Hemodilution; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Heparitin Sulfate; Hirudin Therapy; Humans; Immunoglobulin Fab Fragments; Perfusion; Pipecolic Acids; Platelet Aggregation Inhibitors; Protamines; Sulfonamides; Thrombocytopenia; Thrombophilia; Thrombosis; Tirofiban; Tyrosine

2001

Trials

15 trial(s) available for arginine and Bleeding

ArticleYear
Safety and preliminary efficacy of argatroban plus dual antiplatelet therapy for acute mild to moderate ischemic stroke with large artery atherosclerosis.
    Brain and behavior, 2022, Volume: 12, Issue:7

    Topics: Arginine; Arteries; Atherosclerosis; Hemorrhage; Humans; Intracranial Hemorrhages; Ischemic Stroke; Pipecolic Acids; Platelet Aggregation Inhibitors; Prospective Studies; Retrospective Studies; Sulfonamides; Treatment Outcome

2022
Ciraparantag, an anticoagulant reversal drug: mechanism of action, pharmacokinetics, and reversal of anticoagulants.
    Blood, 2021, 01-07, Volume: 137, Issue:1

    Topics: Animals; Anticoagulants; Arginine; Blood Coagulation; Female; Half-Life; Hemorrhage; Humans; Male; Piperazines; Rats; Rats, Sprague-Dawley

2021
Targeting Coagulase Activity in Staphylococcus aureus Bacteraemia: A Randomized Controlled Single-Centre Trial of Staphylothrombin Inhibition.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:5

    Topics: Administration, Intravenous; Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Bacteremia; Belgium; Blood Coagulation; Coagulase; Dabigatran; Enoxaparin; Feasibility Studies; Female; Hemorrhage; Humans; Injections, Subcutaneous; Male; Middle Aged; Partial Thromboplastin Time; Pilot Projects; Pipecolic Acids; Prospective Studies; Staphylococcal Infections; Staphylococcus aureus; Sulfonamides; Thrombin; Thrombosis; Time Factors; Treatment Outcome

2018
Argatroban versus Lepirudin in critically ill patients (ALicia): a randomized controlled trial.
    Critical care (London, England), 2014, Oct-25, Volume: 18, Issue:5

    Topics: Aged; Aged, 80 and over; Anticoagulants; Antithrombins; Arginine; Critical Illness; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Partial Thromboplastin Time; Pipecolic Acids; Recombinant Proteins; Renal Insufficiency; Renal Replacement Therapy; Sulfonamides; Surgical Procedures, Operative; Thrombocytopenia

2014
Low dose of argatroban saline flushes anticoagulation in hemodialysis patients with high risk of bleeding.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2010, Volume: 16, Issue:4

    Topics: Anticoagulants; Arginine; Dose-Response Relationship, Drug; Female; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Renal Dialysis; Sodium Chloride; Sulfonamides

2010
Argatroban for elective percutaneous coronary intervention: the ARG-E04 multi-center study.
    International journal of cardiology, 2011, Apr-14, Volume: 148, Issue:2

    Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Anticoagulants; Antithrombins; Arginine; Blood Coagulation; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombosis

2011
A randomized, open-label pilot study comparing desirudin and argatroban in patients with suspected heparin-induced thrombocytopenia with or without thrombosis: PREVENT-HIT Study.
    American journal of therapeutics, 2011, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Aged; Anticoagulants; Arginine; Disease Progression; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Pilot Projects; Pipecolic Acids; Platelet Count; Postoperative Complications; Postoperative Period; Recombinant Proteins; Sulfonamides; Thrombin; Thrombocytopenia; Thrombosis; Treatment Outcome; Young Adult

2011
Bleeding risk factors associated with argatroban therapy in the critically ill.
    Journal of thrombosis and thrombolysis, 2012, Volume: 34, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arginine; Bilirubin; Critical Illness; Female; Hemoglobins; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Aggregation Inhibitors; Platelet Count; Retrospective Studies; Risk Factors; Sulfonamides

2012
Anticoagulant therapy with a selective thrombin inhibitor for acute cerebral infarction: usefulness of coagulation markers for evaluation of efficacy.
    Journal of thrombosis and thrombolysis, 2002, Volume: 13, Issue:3

    Topics: Acute Disease; Aged; Anticoagulants; Antithrombins; Arginine; Biomarkers; Blood Coagulation; Blood Coagulation Tests; Blood Proteins; Cerebral Infarction; Embolism; Female; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Stroke; Sulfonamides; Thrombosis; Treatment Outcome

2002
Transitioning from argatroban to warfarin in heparin-induced thrombocytopenia: an analysis of outcomes in patients with elevated international normalized ratio (INR).
    Journal of thrombosis and thrombolysis, 2005, Volume: 19, Issue:3

    Topics: Adult; Aged; Amputation, Surgical; Arginine; Cause of Death; Female; Hemorrhage; Heparin; Humans; Incidence; International Normalized Ratio; Male; Middle Aged; Pipecolic Acids; Retrospective Studies; Risk Assessment; Sulfonamides; Survival Rate; Thrombocytopenia; Thrombosis; Treatment Outcome; Warfarin

2005
Thrombocytopenia following heparin flush.
    Progress in cardiovascular nursing, 2005,Fall, Volume: 20, Issue:4

    Topics: Amputation, Surgical; Anticoagulants; Arginine; Catheters, Indwelling; Cause of Death; Diagnosis, Differential; Female; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Male; Middle Aged; Partial Thromboplastin Time; Patient Selection; Pipecolic Acids; Platelet Count; Prospective Studies; Recurrence; Sulfonamides; Therapeutic Irrigation; Thrombocytopenia; Thrombosis; Treatment Outcome

2005
Argatroban anticoagulation in critically ill patients.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:5

    Topics: Anticoagulants; Arginine; Critical Illness; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Multiple Organ Failure; Partial Thromboplastin Time; Pipecolic Acids; Sulfonamides; Thrombocytopenia

2007
Clinical laboratory monitoring of a synthetic antithrombin agent, argatroban, using high performance liquid chromatography and functional methods.
    International angiology : a journal of the International Union of Angiology, 1999, Volume: 18, Issue:3

    Topics: Anticoagulants; Antithrombins; Arginine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Hemorrhage; Humans; Male; Myocardial Infarction; Pipecolic Acids; Sensitivity and Specificity; Streptokinase; Sulfonamides; Time Factors

1999
Argatroban and alteplase in patients with acute myocardial infarction: the ARGAMI Study.
    Journal of thrombosis and thrombolysis, 2000, Volume: 10, Issue:3

    Topics: Aged; Angiography; Anticoagulants; Arginine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Partial Thromboplastin Time; Pipecolic Acids; Plasminogen Activators; Sulfonamides; Survival Rate; Time Factors; Tissue Plasminogen Activator

2000
Argatroban anticoagulant therapy in patients with heparin-induced thrombocytopenia.
    Circulation, 2001, Apr-10, Volume: 103, Issue:14

    Topics: Aged; Anticoagulants; Arginine; Blood Coagulation; Blood Coagulation Tests; Diarrhea; Exanthema; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pain; Pipecolic Acids; Purpura; Sulfonamides; Thrombocytopenia; Treatment Outcome

2001

Other Studies

93 other study(ies) available for arginine and Bleeding

ArticleYear
High concentration of symmetric dimethylarginine is associated with low platelet reactivity and increased bleeding risk in patients with acute coronary syndrome.
    Thrombosis research, 2022, Volume: 213

    Topics: Acute Coronary Syndrome; Adenosine Diphosphate; Arginine; Biomarkers; Female; Hemorrhage; Humans; Male; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors

2022
Novel insight into Robert's cytoprotection: complex therapeutic effect of cytoprotective pentadecapeptide pentadecapeptide BPC 157 in rats with perforated stomach throughout modulation of nitric oxide-system. Comparison with L-arginine, ranitidine and pan
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2021, Volume: 72, Issue:6

    Topics: Animals; Arginine; Cytoprotection; Hemorrhage; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pantoprazole; Peptide Fragments; Proteins; Ranitidine; Rats; Rats, Wistar; Stomach Diseases

2021
A Fibrinogen-Mimicking, Activated-Platelet-Sensitive Nanocoacervate Enhances Thrombus Targeting and Penetration of Tissue Plasminogen Activator for Effective Thrombolytic Therapy.
    Advanced healthcare materials, 2022, Volume: 11, Issue:19

    Topics: Animals; Arginine; Aspartic Acid; Chitosan; Fibrinogen; Fibrinolytic Agents; Glycine; Hemorrhage; Hemostatics; Mice; Oligopeptides; Thrombolytic Therapy; Thrombosis; Tissue Plasminogen Activator

2022
Therapy of the rat hemorrhagic cystitis induced by cyclophosphamide. Stable gastric pentadecapeptide BPC 157, L-arginine, L-NAME.
    European journal of pharmacology, 2019, Oct-15, Volume: 861

    Topics: Animals; Anti-Ulcer Agents; Arginine; Cyclophosphamide; Cystitis; Female; Hemorrhage; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proteins; Rats; Rats, Wistar

2019
Utilization and Outcomes of Children Treated with Direct Thrombin Inhibitors on Paracorporeal Ventricular Assist Device Support.
    ASAIO journal (American Society for Artificial Internal Organs : 1992), 2020, Volume: 66, Issue:8

    Topics: Adolescent; Antithrombins; Arginine; Child; Child, Preschool; Female; Heart-Assist Devices; Hemorrhage; Hirudins; Humans; Infant; Male; North America; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Stroke; Sulfonamides; Thrombosis; Treatment Outcome

2020
[Complex management of type 2 heparin-induced thrombocytopenia in patients with major bleeding tendency: two case report].
    Annales de biologie clinique, 2020, Dec-01, Volume: 78, Issue:6

    Topics: 4-Hydroxycoumarins; Aged; Anticoagulants; Arginine; Blood Coagulation Disorders; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Hemorrhage; Heparin; Humans; Indenes; Intracranial Thrombosis; Male; Middle Aged; Neurosurgical Procedures; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Vitamin K

2020
Treatment and outcomes of heparin-induced thrombocytopenia (HIT) in patients with neoplasm, a case series.
    Journal of thrombosis and thrombolysis, 2021, Volume: 51, Issue:3

    Topics: Aged; Anticoagulants; Arginine; Canada; Female; Fondaparinux; Gastrointestinal Neoplasms; Hematologic Neoplasms; Hemorrhage; Heparin; Humans; Male; Patient Acuity; Pipecolic Acids; Platelet Count; Retrospective Studies; Risk Adjustment; Sulfonamides; Thrombocytopenia

2021
Importance of endothelial dysfunction biomarkers in patients with Crimean-Congo hemorrhagic fever.
    Journal of medical virology, 2017, Volume: 89, Issue:12

    Topics: Adult; Aged; Arginine; Biomarkers; Cytokines; Endothelin-1; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Hemorrhage; Hemorrhagic Fever Virus, Crimean-Congo; Hemorrhagic Fever, Crimean; Humans; Kinetics; Male; Middle Aged; Prognosis; Prospective Studies; ROC Curve; Thrombomodulin; Turkey; von Willebrand Factor

2017
Argininosuccinate synthase 1 (ASS1): A marker of unclassified hepatocellular adenoma and high bleeding risk.
    Hepatology (Baltimore, Md.), 2017, Volume: 66, Issue:6

    Topics: Adenoma, Liver Cell; Adult; Arginine; Argininosuccinate Synthase; Biomarkers, Tumor; Cohort Studies; Female; Hemorrhage; Humans; Laser Capture Microdissection; Liver; Liver Neoplasms; Mass Spectrometry; Middle Aged; Proteome

2017
Tissue plasminogen activator mediates deleterious complement cascade activation in stroke.
    PloS one, 2017, Volume: 12, Issue:7

    Topics: Animals; Arginine; Benzhydryl Compounds; Brain; Brain Edema; Cell Death; Cells, Cultured; Complement C3; Endothelial Cells; Fibrinolysin; Hemoglobins; Hemorrhage; Humans; Immunohistochemistry; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Stroke; Tissue Plasminogen Activator

2017
Use of Fondaparinux Off-Label or Approved Anticoagulants for Management of Heparin-Induced Thrombocytopenia.
    Journal of the American College of Cardiology, 2017, Nov-28, Volume: 70, Issue:21

    Topics: Anticoagulants; Arginine; Chondroitin Sulfates; Dermatan Sulfate; Factor Xa Inhibitors; Female; Fondaparinux; Hemorrhage; Heparin; Heparitin Sulfate; Hirudins; Hospital Mortality; Hospitalization; Humans; Male; Necrosis; Off-Label Use; Partial Thromboplastin Time; Patient Safety; Pipecolic Acids; Polysaccharides; Recombinant Proteins; Registries; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thromboembolism; Treatment Outcome

2017
A chemically-modified inactive antithrombin as a potent antagonist of fondaparinux and heparin anticoagulant activity.
    Journal of thrombosis and haemostasis : JTH, 2013, Volume: 11, Issue:6

    Topics: Animals; Anticoagulants; Antithrombins; Arginine; Diacetyl; Drug Design; Female; Fondaparinux; Hemorrhage; Heparin; Heparin Antagonists; Humans; Mass Spectrometry; Mice; Partial Thromboplastin Time; Polysaccharides; Recombinant Proteins; Risk

2013
Administration of human recombinant activated protein C is not associated with pancreatic parenchymal haemorrhage in L-arginine-induced experimental acute pancreatitis.
    JOP : Journal of the pancreas, 2013, Nov-10, Volume: 14, Issue:6

    Topics: Acute Disease; Amylases; Animals; Anti-Infective Agents; Arginine; Hemorrhage; Humans; Injections, Intraperitoneal; Lipase; Male; Pancreas; Pancreatic Diseases; Pancreatitis; Protein C; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Treatment Outcome

2013
Intravenous warfarin and heparin-induced thrombocytopenia: making the diagnosis, management, modern monitoring, and multidisciplinary care.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:2

    Topics: Aged; Anticoagulants; Antithrombins; Arginine; Cardiac Surgical Procedures; Hemorrhage; Heparin; Humans; Infusions, Intravenous; Male; Pipecolic Acids; Pulmonary Embolism; Sulfonamides; Thrombocytopenia; Thrombosis; Warfarin

2014
Trends in parenteral direct thrombin inhibitor use in pediatric patients: analysis of a large administrative database.
    Archives of pathology & laboratory medicine, 2014, Volume: 138, Issue:9

    Topics: Adolescent; Age Factors; Antithrombins; Arginine; Child; Child, Preschool; Databases, Factual; Female; Health Information Systems; Hemorrhage; Hirudins; Humans; Incidence; Infant; Infant, Newborn; Infusions, Parenteral; Male; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia; Young Adult

2014
Efficacy and safety of argatroban and bivalirudine in patients with suspected heparin-induced thrombocytopenia.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:2

    Topics: Aged; Anticoagulants; Arginine; Female; Hemorrhage; Heparin; Hirudins; Humans; Male; Middle Aged; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia

2015
Safety and economic considerations of argatroban use in critically ill patients: a retrospective analysis.
    Journal of cardiothoracic surgery, 2015, Feb-07, Volume: 10

    Topics: Adult; Aged; Anticoagulants; Arginine; Critical Illness; Dose-Response Relationship, Drug; Drug Costs; Female; Germany; Health Care Costs; Hemorrhage; Heparin; Humans; Intensive Care Units; Male; Middle Aged; Pipecolic Acids; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thromboembolism

2015
Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Amputation, Surgical; Animals; Anticoagulants; Arginine; Drug Evaluation, Preclinical; Hemorrhage; Hemostasis; Heparin; Male; NG-Nitroarginine Methyl Ester; Peptide Fragments; Proteins; Rats, Wistar; Thrombocytopenia; Warfarin

2015
Novel oral anticoagulants and reversal agents: Considerations for clinical development.
    American heart journal, 2015, Volume: 169, Issue:6

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Cardiovascular Diseases; Factor Xa; Factor Xa Inhibitors; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Stroke

2015
Comparison of bivalirudin to lepirudin and argatroban in patients with heparin-induced thrombocytopenia.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Sep-01, Volume: 72, Issue:17 Suppl 2

    Topics: Aged; Anticoagulants; Antithrombins; Arginine; Dose-Response Relationship, Drug; Female; Hemorrhage; Heparin; Hirudins; Humans; International Normalized Ratio; Male; Middle Aged; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia

2015
A new experimental rat model of pancreatitis using Ecballium elaterium.
    International journal of surgery (London, England), 2015, Volume: 23, Issue:Pt A

    Topics: Acute Disease; Amylases; Animals; Antioxidants; Arginine; Cucurbitaceae; Disease Models, Animal; Edema; Hemorrhage; Interleukin-1beta; Interleukin-6; Lung; Male; Malondialdehyde; Mice; Necrosis; Pancreas; Pancreatitis; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2015
Outcomes of Argatroban Treatment in Patients With Atherothrombotic Stroke: Observational Nationwide Study in Japan.
    Stroke, 2016, Volume: 47, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antithrombins; Arginine; Case-Control Studies; Cohort Studies; Female; Hemorrhage; Humans; Intracranial Arteriosclerosis; Intracranial Thrombosis; Japan; Male; Middle Aged; Odds Ratio; Pipecolic Acids; Practice Guidelines as Topic; Retrospective Studies; Stroke; Sulfonamides; Treatment Outcome

2016
Reversal strategies for non-vitamin K antagonist oral anticoagulants: a critical appraisal of available evidence and recommendations for clinical management-a joint position paper of the European Society of Cardiology Working Group on Cardiovascular Pharm
    European heart journal, 2017, 06-07, Volume: 38, Issue:22

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Antidotes; Arginine; Consensus; Dabigatran; Evidence-Based Medicine; Factor Xa; Forecasting; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Risk Factors; Thrombosis; Vitamin K

2017
[Antidotes for the new oral anticoagulants: Reality and expectations].
    Medicina clinica, 2016, Jun-03, Volume: 146, Issue:11

    Topics: Administration, Oral; Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Coagulants; Factor Xa; Hemorrhage; Humans; Piperazines; Recombinant Proteins; Treatment Outcome

2016
Mutation in a highly conserved glycine residue in strand 5B of plasminogen activator inhibitor 1 causes polymerisation.
    Thrombosis and haemostasis, 2017, 05-03, Volume: 117, Issue:5

    Topics: Aged; Amino Acid Substitution; Animals; Arginine; Chlorocebus aethiops; Conserved Sequence; COS Cells; Cytosine; DNA Mutational Analysis; Exons; Female; Genetic Predisposition to Disease; Glycine; Guanine; Hemorrhage; Hemostasis; Homozygote; Humans; Models, Molecular; Molecular Weight; Mutation; Phenotype; Plasminogen Activator Inhibitor 1; Polymerization; Protein Conformation; Structure-Activity Relationship; Transfection

2017
What is the optimal anticoagulation level with argatroban during percutaneous coronary intervention?
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2008, Volume: 19, Issue:5

    Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Female; Heart Diseases; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Retrospective Studies; Sulfonamides; Thrombocytopenia; Whole Blood Coagulation Time

2008
Risk factors for major bleeding in patients with heparin-induced thrombocytopenia treated with argatroban: a retrospective study.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticoagulants; Arginine; Blood Coagulation; Drug Monitoring; Female; Hemorrhage; Heparin; Humans; Lung Diseases; Male; Middle Aged; Odds Ratio; Partial Thromboplastin Time; Pipecolic Acids; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonamides; Thrombocytopenia; Thrombosis; Young Adult

2008
Anticoagulation with the direct thrombin inhibitor argatroban in patients presenting with acute coronary syndromes.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Aug-01, Volume: 74, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Cardiac Catheterization; Female; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Odds Ratio; Pipecolic Acids; Retrospective Studies; Risk Assessment; Sulfonamides; Thrombin; Treatment Outcome

2009
Clinical investigation in ACS and PCI: shooting in the dark at a moving target.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2009, Aug-01, Volume: 74, Issue:2

    Topics: Acute Coronary Syndrome; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Evidence-Based Medicine; Hemorrhage; Humans; Myocardial Infarction; Myocardial Revascularization; Pipecolic Acids; Research Design; Risk Assessment; Sulfonamides; Thrombin; Treatment Outcome

2009
Pharmacokinetic and pharmacodynamic basis for effective argatroban dosing in pediatrics.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:1

    Topics: Adolescent; Arginine; Bilirubin; Body Weight; Child; Child, Preschool; Computer Simulation; Dose-Response Relationship, Drug; Female; Hemorrhage; Humans; Infant; Infant, Newborn; Male; Models, Biological; Partial Thromboplastin Time; Pipecolic Acids; Platelet Aggregation Inhibitors; Sulfonamides

2011
Safety and efficacy of the argatroban therapy during the early post-cardiac surgery period.
    Journal of thrombosis and thrombolysis, 2010, Volume: 30, Issue:3

    Topics: Aged; Aged, 80 and over; Arginine; Cardiac Surgical Procedures; Drug-Related Side Effects and Adverse Reactions; Female; Hemorrhage; Hospital Mortality; Humans; Male; Middle Aged; Pipecolic Acids; Postoperative Care; Postoperative Complications; Retrospective Studies; Sulfonamides; Thrombin; Thrombosis; Treatment Outcome

2010
Venous limb gangrene and fatal hemorrhage: adverse consequences of HIT "overdiagnosis" in a patient with antiphospholipid syndrome.
    American journal of hematology, 2011, Volume: 86, Issue:2

    Topics: Anticoagulants; Antiphospholipid Syndrome; Arginine; Diagnostic Errors; Drug Monitoring; Fatal Outcome; Female; Gangrene; Hemorrhage; Humans; Lung Diseases; Middle Aged; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Upper Extremity; Vascular Diseases; Warfarin

2011
Effects of argatroban as an anticoagulant for intermittent veno-venous hemofiltration (IVVH) in patients at high risk of bleeding.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:9

    Topics: Acute Kidney Injury; Anticoagulants; Arginine; Cohort Studies; Female; Follow-Up Studies; Hemofiltration; Hemorrhage; Humans; Male; Middle Aged; Pipecolic Acids; Prognosis; Prospective Studies; Renal Replacement Therapy; Risk Factors; Sulfonamides; Survival Rate

2011
Argatroban therapy in pediatric patients requiring nonheparin anticoagulation: an open-label, safety, efficacy, and pharmacokinetic study.
    Pediatric blood & cancer, 2011, Jul-01, Volume: 56, Issue:7

    Topics: Anticoagulants; Arginine; Child; Child, Preschool; Female; Hemorrhage; Heparin; Humans; Infant; Liver Function Tests; Male; Pipecolic Acids; Platelet Aggregation Inhibitors; Prospective Studies; Sulfonamides; Survival Rate; Thrombocytopenia; Thrombosis; Tissue Distribution; Treatment Outcome

2011
Implementation of an individualized argatroban protocol in an academic medical center.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2011, Jul-15, Volume: 68, Issue:14

    Topics: Academic Medical Centers; Arginine; Clinical Protocols; Hemorrhage; Humans; Pipecolic Acids; Precision Medicine; Prothrombin Time; Retrospective Studies; Sulfonamides

2011
The impact of L-NAME and L-arginine chronic toxicity induced lesions on ascites--pulmonary hypertension syndrome development in broiler chickens.
    Collegium antropologicum, 2011, Volume: 35, Issue:2

    Topics: Animals; Arginine; Ascites; Chickens; Hemorrhage; Hypertension, Pulmonary; Injections, Intraperitoneal; Male; NG-Nitroarginine Methyl Ester; Poultry Diseases; Toxicity Tests, Chronic

2011
Recognition of heparin-induced thrombocytopenia and initiation of argatroban therapy after cardiothoracic surgery in the intensive care unit.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:5

    Topics: Antibodies; Anticoagulants; Arginine; Cardiac Surgical Procedures; Drug Substitution; Georgia; Hemorrhage; Heparin; Humans; Intensive Care Units; Pipecolic Acids; Platelet Factor 4; Predictive Value of Tests; Retrospective Studies; Risk Assessment; Risk Factors; Sulfonamides; Thoracic Surgical Procedures; Thrombocytopenia; Thrombosis; Time Factors; Treatment Outcome

2012
The therapeutic management of bleeding and thrombotic disorders complicating CNS malignancies.
    Current treatment options in oncology, 2012, Volume: 13, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Anticoagulants; Arginine; Bevacizumab; Central Nervous System Neoplasms; Fondaparinux; Glioblastoma; Glioma; Hemorrhage; Heparin, Low-Molecular-Weight; Hirudins; Humans; Pipecolic Acids; Polysaccharides; Postoperative Complications; Pulmonary Embolism; Recombinant Proteins; Sulfonamides; Thrombocytopenia; Vena Cava Filters; Venous Thromboembolism; Venous Thrombosis; Warfarin

2012
Safety and effectiveness outcomes of an inpatient collaborative drug therapy management service for direct thrombin inhibitors.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2012, Nov-15, Volume: 69, Issue:22

    Topics: Adult; Aged; Antithrombins; Arginine; Cohort Studies; Cooperative Behavior; Drug Monitoring; Female; Hemorrhage; Heparin; Hirudins; Humans; Inpatients; Male; Medication Errors; Middle Aged; Outcome Assessment, Health Care; Partial Thromboplastin Time; Peptide Fragments; Pharmacists; Pharmacy Service, Hospital; Pipecolic Acids; Recombinant Proteins; Retrospective Studies; Sulfonamides; Thrombocytopenia; Time Factors

2012
Biochemical and biological activities of the venom of a new species of pitviper from Vietnam, Triceratolepidophis sieversorum.
    Toxicon : official journal of the International Society on Toxinology, 2003, Volume: 41, Issue:2

    Topics: Animals; Arginine; Caseins; Cattle; Crotalid Venoms; Dose-Response Relationship, Drug; Esters; Female; Hemorrhage; Humans; Hydrolysis; Injections, Intraperitoneal; Kallikreins; Lethal Dose 50; Mice; Muscle, Skeletal; Phospholipases A; Skin; Species Specificity; Vietnam; Viperidae

2003
Antithrombotic properties of a direct thrombin inhibitor with a prolonged half-life and AT-mediated factor Xa inhibitory activity.
    Journal of thrombosis and haemostasis : JTH, 2003, Volume: 1, Issue:9

    Topics: Animals; Antithrombin III; Arginine; Blood Coagulation Tests; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Factor Xa Inhibitors; Fibrinolytic Agents; Fondaparinux; Half-Life; Hemorrhage; Heparin; Male; Molecular Structure; Oligosaccharides; Pipecolic Acids; Polysaccharides; Rabbits; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombolytic Therapy; Thrombosis

2003
Involvement of nitric oxide and hyperbaric oxygen in the pathogenesis of cyclophosphamide induced hemorrhagic cystitis in rats.
    The Journal of urology, 2003, Volume: 170, Issue:6 Pt 1

    Topics: Animals; Antineoplastic Agents, Alkylating; Arginine; Cyclophosphamide; Cystitis; Hemorrhage; Hyperbaric Oxygenation; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Urinary Bladder

2003
Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats.
    Urological research, 2004, Volume: 32, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Arginine; Cyclophosphamide; Cystitis; Disease Models, Animal; Enzyme Inhibitors; Female; Hemorrhage; Isothiuronium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley

2004
L-arginine improves wound healing after trauma-hemorrhage by increasing collagen synthesis.
    The Journal of trauma, 2005, Volume: 59, Issue:1

    Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Chromatography, High Pressure Liquid; Collagen; Hemorrhage; Hydroxyproline; Male; Mice; Mice, Inbred C3H; Random Allocation; Transforming Growth Factor beta; Wound Healing; Wounds and Injuries

2005
A comparison of lepirudin and argatroban outcomes.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2005, Volume: 11, Issue:4

    Topics: Aged; Anticoagulants; Arginine; Female; Hemorrhage; Hirudins; Humans; Male; Pipecolic Acids; Recombinant Proteins; Sulfonamides; Thrombin; Treatment Outcome

2005
Effect of nitric oxide on toll-like receptor 2 and 4 gene expression in rats with acute lung injury complicated by acute hemorrhage necrotizing pancreatitis.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2005, Volume: 4, Issue:4

    Topics: Animals; Arginine; Base Sequence; DNA Primers; Gene Expression Regulation; Hemorrhage; Inflammation; Lung; Male; Nitric Oxide; Pancreatitis, Acute Necrotizing; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 2; Toll-Like Receptor 4

2005
Heparin-induced thrombocytopenia from venous thromboembolism treatment.
    Journal of internal medicine, 2005, Volume: 258, Issue:6

    Topics: Amputation, Surgical; Anticoagulants; Arginine; Drug Administration Schedule; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Pipecolic Acids; Platelet Count; Randomized Controlled Trials as Topic; Recurrence; Retrospective Studies; Sulfonamides; Thrombocytopenia; Thromboembolism; Treatment Outcome; Warfarin

2005
Intrathecal cGMP elicits pressor responses and maintains mean blood pressure during haemorrhage in anaesthetized rats.
    The Journal of physiology, 2007, Jun-01, Volume: 581, Issue:Pt 2

    Topics: Anesthesia; Animals; Arginine; Blood Pressure; Cyclic GMP; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Heart Rate; Hemorrhage; Injections, Spinal; Nitric Oxide; Oxadiazoles; Pressoreceptors; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Sympathetic Nervous System

2007
Antioxidants combined with NO donor enhance systemic inflammation in acute lung injury in rats.
    Scandinavian cardiovascular journal : SCJ, 2007, Volume: 41, Issue:3

    Topics: Animals; Antioxidants; Arginine; Catalase; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Hemorrhage; Inflammation; Intestines; Male; Neutrophil Infiltration; Nitric Oxide Donors; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Distress Syndrome; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2007
Effect of body mass index on Argatroban therapy during percutaneous coronary intervention.
    Journal of thrombosis and thrombolysis, 2008, Volume: 25, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Anticoagulants; Arginine; Blood Coagulation; Body Mass Index; Coronary Artery Disease; Female; Hemorrhage; Heparin; Humans; Male; Middle Aged; Obesity; Pipecolic Acids; Retrospective Studies; Sulfonamides; Thrombocytopenia

2008
Fondaparinux versus direct thrombin inhibitor therapy for the management of heparin-induced thrombocytopenia (HIT)--bridging the River Coumarin.
    Thrombosis and haemostasis, 2008, Volume: 99, Issue:1

    Topics: Acute Disease; Anticoagulants; Arginine; Blood Coagulation; Factor Xa Inhibitors; Fondaparinux; Hemorrhage; Heparin; Hirudins; Humans; International Normalized Ratio; Pipecolic Acids; Platelet Count; Polysaccharides; Recombinant Proteins; Research Design; Sulfonamides; Thrombin; Thrombocytopenia; Treatment Outcome; Venous Thrombosis; Warfarin

2008
Alpha-defensin-like product and asymmetric dimethylarginine increase in mesenteric lymph after hemorrhage in anesthetized rat.
    Shock (Augusta, Ga.), 2008, Volume: 30, Issue:4

    Topics: alpha-Defensins; Anesthesia; Animals; Antimicrobial Cationic Peptides; Arginine; Enzyme-Linked Immunosorbent Assay; Hemorrhage; Inflammation; Intestinal Mucosa; Lymph Nodes; Male; Phospholipases A2; Rats; Rats, Sprague-Dawley; Time Factors

2008
Hemin arginate-induced heme oxygenase 1 expression improves liver microcirculation and mediates an anti-inflammatory cytokine response after hemorrhagic shock.
    Shock (Augusta, Ga.), 2008, Volume: 29, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arginine; Cytokines; Heat-Shock Proteins; Heme; Heme Oxygenase-1; Hemorrhage; Interleukin-10; Liver; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Shock, Hemorrhagic; Tumor Necrosis Factor-alpha

2008
Hemorrhagic and proteolytic activities of Thailand snake venoms.
    Biochemical pharmacology, 1967, Volume: 16, Issue:11

    Topics: Animals; Arginine; Caseins; Hemorrhage; Injections, Subcutaneous; Mice; Peptide Hydrolases; Rabbits; Snakes; Thailand; Tyrosine; Venoms

1967
Diminished effect of inhibition of nitric oxide synthase on regional cerebral vascular resistance in conscious and in isoflurane anesthetized rats during hemorrhage.
    Brain research, 1993, Dec-10, Volume: 630, Issue:1-2

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Brain; Hemorrhage; Isoflurane; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenylephrine; Rats; Vascular Resistance

1993
The effect of hemorrhagic hypotension and retransfusion and 7-nitro-indazole on rCBF, NOS catalytic activity, and cortical NO content in the cat.
    Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738

    Topics: Acetylcholine; Adenosine Triphosphate; Amino Acid Oxidoreductases; Analgesics; Animals; Arginine; Blood Pressure; Blood Transfusion; Brain; Cats; Cerebral Arteries; Cerebral Cortex; Cerebrovascular Circulation; Electroencephalography; Hemorrhage; Hypotension; Indazoles; Male; Molsidomine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Organ Specificity; Parietal Lobe; Pituitary Gland; Regional Blood Flow; Spinal Cord; Vasodilator Agents

1994
Nitric oxide contributes to multiorgan oxidative stress in acute experimental pancreatitis.
    Scandinavian journal of gastroenterology, 1994, Volume: 29, Issue:10

    Topics: Acute Disease; Amylases; Animals; Arginine; Hemorrhage; Liver; Lung; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Wistar; Sulfhydryl Compounds

1994
Influence of nitric oxide on the hemodynamic response to hemorrhage in conscious rabbits.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Amino Acid Oxidoreductases; Analysis of Variance; Animals; Arginine; Blood Flow Velocity; Blood Pressure; Female; Heart Rate; Hemodynamics; Hemorrhage; Hindlimb; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Regional Blood Flow; Splanchnic Circulation; Time Factors

1995
Evidence of a role for endothelium-derived nitric oxide in the regulation of vascular tone during acute haemorrhage.
    Acta physiologica Scandinavica, 1995, Volume: 154, Issue:3

    Topics: Acute Disease; Animals; Arginine; Cats; Endothelium, Vascular; Enzyme Inhibitors; Hemorrhage; Muscle Tonus; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Vascular Resistance

1995
Effect of inhibition of nitric oxide synthesis on the cardiovascular and endocrine responses to hemorrhage in conscious rabbits.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1995, Volume: 18, Issue:1

    Topics: Animals; Arginine; Arginine Vasopressin; Baroreflex; Blood Pressure; Enzyme Inhibitors; Hemorrhage; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Renin

1995
Viscoelastic behavior of "in situ" aortic wall during hemorrhagic hypotension.
    The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 2

    Topics: Animals; Aorta; Arginine; Blood Pressure; Elasticity; Gases; Hemorrhage; Hydrogen-Ion Concentration; Hypotension; Indomethacin; Male; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Viscosity

1995
Possible role for oxygen free radicals in the regulation of renal nitric oxide synthesis and blood flow.
    American journal of surgery, 1995, Volume: 169, Issue:6

    Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Down-Regulation; Free Radicals; Hemorrhage; Kidney; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxygen; Rats; Renal Circulation; Reperfusion Injury; Vasoconstriction

1995
Disturbances in blood pressure homeostasis modify GABA release in the locus coeruleus.
    Neuroreport, 1994, Sep-08, Volume: 5, Issue:14

    Topics: Animals; Arginine; Blood Pressure; Blood Volume; gamma-Aminobutyric Acid; Hemorrhage; Homeostasis; Locus Coeruleus; Male; Neurons; Nitroprusside; Norepinephrine; Phenylephrine; Rats; Rats, Sprague-Dawley; Taurine

1994
Stroma-free hemoglobin increases blood pressure and GFR in the hypotensive rat: role of nitric oxide.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 77, Issue:5

    Topics: Animals; Arginine; Blood Gas Analysis; Blood Pressure; Blood Substitutes; Glomerular Filtration Rate; Hemoglobins; Hemorrhage; Hypotension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Sprague-Dawley; Sodium

1994
Nitric oxide inhibition causes intrauterine growth retardation and hind-limb disruptions in rats.
    American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:5

    Topics: Amniotic Fluid; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Female; Fetal Diseases; Fetal Growth Retardation; Fetus; Hemorrhage; Hindlimb; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley

1994
Influence of endothelium-derived relaxing factor on platelet function and hemostasis in vivo.
    Thrombosis research, 1994, Apr-01, Volume: 74, Issue:1

    Topics: Animals; Arginine; Blood Platelets; Blood Pressure; Carbachol; Female; Hemoglobins; Hemorrhage; Hemostasis; Male; Nitric Oxide; Nitroarginine; Rabbits; Statistics as Topic

1994
Requirements for neutrophil products and L-arginine in ischemia-reperfusion injury.
    The American journal of pathology, 1993, Volume: 142, Issue:4

    Topics: Animals; Arginine; Capillary Permeability; Complement Hemolytic Activity Assay; Hemorrhage; Hindlimb; Ischemia; Lung; Male; Muscles; Neutrophils; Peroxidase; Rats; Rats, Inbred Strains; Reperfusion Injury; Time Factors

1993
L-Arginine reverses the abolition of hypovolaemic decompensation by N-nitro-L-arginine methyl ester and naloxone in conscious rabbits.
    European journal of pharmacology, 1995, Dec-29, Volume: 294, Issue:2-3

    Topics: Animals; Arginine; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hemodynamics; Hemorrhage; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Shock, Hemorrhagic

1995
Regional heterogeneity and differential vulnerability of cerebral and spinal vascular CO2-responsiveness during graded haemorrhagic hypotension.
    Acta physiologica Hungarica, 1996, Volume: 84, Issue:3

    Topics: Animals; Arginine; Blood Pressure; Blood Vessels; Carbon Dioxide; Cats; Cerebrovascular Circulation; Gases; Hemorrhage; Hypercapnia; Hypocapnia; Hypotension; Male; Reference Values; Spinal Cord

1996
Antithrombotic and hemorrhagic effects of DX-9065a, a direct and selective factor Xa inhibitor: comparison with a direct thrombin inhibitor and antithrombin III-dependent anticoagulants.
    Thrombosis and haemostasis, 1997, Volume: 78, Issue:5

    Topics: Animals; Anticoagulants; Antithrombin III; Arginine; Bleeding Time; Blood Coagulation; Disease Models, Animal; Factor Xa Inhibitors; Hemorrhage; Heparin, Low-Molecular-Weight; Male; Naphthalenes; Peptide Hydrolases; Pipecolic Acids; Propionates; Rats; Rats, Wistar; Sulfonamides; Thrombin; Thrombosis

1997
Effect of a synthetic factor Xa inhibitor, YM-60828, on blood vessel patency in combination with a thrombolytic agent and on blood loss from the operation site in a rat model of arterial thrombosis.
    Thrombosis and haemostasis, 1998, Volume: 79, Issue:4

    Topics: Animals; Anticoagulants; Arginine; Blood Loss, Surgical; Carotid Arteries; Carotid Artery Thrombosis; Drug Evaluation, Preclinical; Hemorrhage; Heparin; Male; Naphthalenes; Pipecolic Acids; Piperidines; Rats; Recurrence; Reperfusion; Serine Proteinase Inhibitors; Sulfonamides; Thrombolytic Therapy; Time Factors; Tissue Plasminogen Activator

1998
Purification, cDNA cloning and molecular characteristic of a fibrinolytic enzyme from the venom of Agkistrodon acutus.
    Journal of natural toxins, 1998, Volume: 7, Issue:2

    Topics: Agkistrodon; Amino Acid Sequence; Animals; Arginine; Base Sequence; Blotting, Western; Cloning, Molecular; Crotalid Venoms; DNA, Complementary; Escherichia coli; Hemorrhage; Male; Metalloendopeptidases; Mice; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid

1998
L-arginine restores the depressed cardiac output and regional perfusion after trauma-hemorrhage.
    Surgery, 1998, Volume: 124, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Cardiac Output; Digestive System; Hemorrhage; Interleukin-6; Kidney; Laparotomy; Liver; Lung; Male; Mesentery; Muscle, Skeletal; Pancreas; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Resuscitation; Skin; Soft Tissue Injuries; Vascular Resistance

1998
L-Arginine restores splenocyte functions after trauma and hemorrhage potentially by improving splenic blood flow.
    The American journal of physiology, 1999, Volume: 276, Issue:1

    Topics: Animals; Arginine; Cell Division; Cells, Cultured; Enzyme Inhibitors; Glucocorticoids; Guanidines; Hemorrhage; Interleukin-2; Male; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Spleen; Wounds and Injuries

1999
Pharmacological effects of a novel recombinant hirudin, CX-397, in vivo and in vitro: comparison with recombinant hirudin variant-1, heparin, and argatroban.
    Thrombosis and haemostasis, 1999, Volume: 81, Issue:2

    Topics: Amino Acid Sequence; Animals; Arginine; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; Chlorides; Drug Evaluation, Preclinical; Ferric Compounds; Fibrinolytic Agents; Glass; Hemorrhage; Heparin; Hirudin Therapy; Hirudins; Molecular Sequence Data; Pipecolic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Sulfonamides; Thrombin; Thrombosis; Vena Cava, Inferior; Venous Thrombosis

1999
Prevention of the hemorrhagic hypotension-induced hepatic arterial vasoconstriction by L-arginine and naloxone.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:5

    Topics: Animals; Arginine; Cats; Drug Evaluation, Preclinical; Hemorrhage; Hypotension; Liver; Male; Naloxone; Nitroarginine; Regional Blood Flow; Vasoconstriction

1999
Role of nitric oxide in regulation of renal sympathetic nerve activity during hemorrhage in conscious rats.
    The American journal of physiology, 1999, Volume: 277, Issue:1

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine; Blood Pressure; Consciousness; Enzyme Inhibitors; Heart Rate; Hemorrhage; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperidines; Quinolones; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System

1999
L-arginine attenuates trauma-hemorrhage-induced liver injury.
    Critical care medicine, 2000, Volume: 28, Issue:9

    Topics: Animals; Arginine; Citrulline; Endothelium, Vascular; Glutathione Transferase; Hemodynamics; Hemorrhage; Immunity, Cellular; Liver; Male; Neutrophil Infiltration; Nitric Oxide; Ornithine; Prospective Studies; Rats; Rats, Sprague-Dawley; Resuscitation

2000
Argatroban for treatment of heparin-induced thrombocytopenia.
    The Medical letter on drugs and therapeutics, 2001, Feb-05, Volume: 43, Issue:1097

    Topics: Arginine; Health Expenditures; Hemorrhage; Heparin; Humans; Pipecolic Acids; Sulfonamides; Thrombocytopenia; Thrombosis

2001
The influence of L-arginine on heart rate and tissue oxygen extraction in haemorrhaged rabbits.
    Pharmacological research, 2001, Volume: 43, Issue:4

    Topics: Acid-Base Equilibrium; Animals; Arginine; Blood Pressure; Blood Proteins; Heart Rate; Hematocrit; Hemoglobins; Hemorrhage; Monitoring, Physiologic; Oxygen; Rabbits; Stereoisomerism; Survival Rate; Water-Electrolyte Balance

2001
The antithrombotic efficacy of AT-1459, a novel, direct thrombin inhibitor, in rat models of venous and arterial thrombosis.
    Thrombosis and haemostasis, 2001, Volume: 86, Issue:6

    Topics: Administration, Oral; Amidines; Animals; Arginine; Azepines; Bleeding Time; Carotid Artery Thrombosis; Dalteparin; Drug Evaluation, Preclinical; Fibrinolytic Agents; Hemorrhage; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Molecular Structure; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Sulfonamides; Thrombin; Vena Cava, Inferior; Venous Thrombosis; Warfarin

2001
Nitric oxide inhibition in rats improves blood pressure and renal function during hypovolemic shock.
    The American journal of physiology, 1991, Volume: 261, Issue:5 Pt 2

    Topics: Animals; Arginine; Blood Pressure; Glomerular Filtration Rate; Hemorrhage; Kidney; Male; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred Strains; Reference Values; Renal Circulation; Shock; Vascular Resistance

1991
Role of nitric oxide in maintaining vascular integrity in endotoxin-induced acute intestinal damage in the rat.
    British journal of pharmacology, 1990, Volume: 101, Issue:4

    Topics: Animals; Arginine; Blood Cell Count; Blood Pressure; Blood Vessels; Capillary Permeability; Endotoxins; Hemorrhage; Intestinal Diseases; Iodine Radioisotopes; Jejunum; Lipopolysaccharides; Male; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred Strains

1990
Role of endothelium-derived nitric oxide in the bleeding tendency of uremia.
    The Journal of clinical investigation, 1990, Volume: 86, Issue:5

    Topics: Animals; Arginine; Bleeding Time; Calcimycin; Endothelium, Vascular; Hemorrhage; Male; Nitric Oxide; omega-N-Methylarginine; Platelet Adhesiveness; Platelet Aggregation; Rats; Rats, Inbred Strains; Uremia

1990
Relationship between pharmacological actions and enzymatic activities of the venom of Trimeresurus gramineus.
    Toxicon : official journal of the International Society on Toxinology, 1970, Volume: 8, Issue:2

    Topics: Animals; Antivenins; Arginine; Bradykinin; Capillary Permeability; Caseins; Cysteine; Diaphragm; Edetic Acid; Electrophoresis; Enzymes; Esterases; Eye; Hemorrhage; Histamine Release; Hot Temperature; Mice; Phospholipases; Rabbits; Rats; Snakes; Thrombin; Venoms

1970
Hypophysectomy in diabetic retinopathy. The relationship between the degree of pituitary ablation and ocular response.
    Diabetes, 1974, Volume: 23, Issue:8

    Topics: Adolescent; Adult; Arginine; Blood Glucose; Cryosurgery; Diabetes Mellitus; Diabetic Retinopathy; Female; Fundus Oculi; Growth Hormone; Hemorrhage; Humans; Hypophysectomy; Insulin; Male; Microsurgery; Middle Aged; Pituitary Function Tests; Pituitary Gland; Postoperative Complications; Retinal Hemorrhage; Stereotaxic Techniques; Visual Acuity; Vitreous Body

1974
Observations on the release and clearance of neurophysin and the neurohypophysial hormones in the rat.
    The Journal of endocrinology, 1973, Volume: 57, Issue:2

    Topics: Animals; Arginine; Biological Assay; Calcium Chloride; Cross Reactions; Half-Life; Hemorrhage; Hypophysectomy; Iodine Isotopes; Male; Neurophysins; Oxytocin; Radioimmunoassay; Rats; Vasopressins

1973
Pituitary apoplexy in acromegaly.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:12

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Adult; Arginine; Blood; Blood Glucose; Diabetes Complications; Female; Glucose Tolerance Test; Growth Hormone; Hemorrhage; Humans; Hydrocortisone; Insulin; Islets of Langerhans; Necrosis; Osmolar Concentration; Pituitary Diseases; Thyroxine; Tolbutamide; Urine

1968
Neutralization of Vipera palestinae hemorrhagin by antibody fragments.
    Toxicon : official journal of the International Society on Toxinology, 1971, Volume: 9, Issue:1

    Topics: Alkylation; Animals; Antibodies; Antigen-Antibody Reactions; Arginine; Esterases; Esters; Hemorrhage; Immunoglobulin G; Immunoglobulins; Neutralization Tests; Oxidation-Reduction; Papain; Pepsin A; Peptide Hydrolases; Rabbits; Snakes; Sulfonic Acids; Toluene; Venoms

1971
The effect of hydration on vasopressin and neurophysin release in the rat.
    The Journal of endocrinology, 1971, Volume: 51, Issue:2

    Topics: Animals; Arginine; Biological Assay; Hemorrhage; Male; Osmolar Concentration; Pituitary Hormones, Posterior; Radioimmunoassay; Rats; Sodium Chloride; Vasopressins; Water; Water Deprivation; Water Intoxication; Water-Electrolyte Balance

1971
[Cross circulation experiments with unanesthetized rats. 3. Clearance and volume of distribution of exogenous and endogenous ADH].
    Pflugers Archiv : European journal of physiology, 1969, Volume: 311, Issue:4

    Topics: Animals; Arginine; Hemorrhage; Metabolic Clearance Rate; Parabiosis; Rats; Time Factors; Vasopressins

1969
The effect of acute extracellular fluid volume expansion and acute haemorrhage on plasma antidiuretic hormone and oxytocin levels in dogs.
    The Journal of physiology, 1968, Volume: 196, Issue:2

    Topics: Animals; Arginine; Body Fluids; Dogs; Extracellular Space; Hemorrhage; Natriuresis; Oxytocin; Vasopressins

1968
The release, clearance and plasma protein binding of oxytocin in the anaesthetized rat.
    The Journal of endocrinology, 1969, Volume: 43, Issue:2

    Topics: Anesthesia; Animals; Arginine; Blood Proteins; Female; Hemorrhage; Kidney; Metabolic Clearance Rate; Oxytocin; Pentobarbital; Pressure; Protein Binding; Rats; Temperature; Time Factors; Vasopressins

1969