arginine and Becker Muscular Dystrophy

arginine has been researched along with Becker Muscular Dystrophy in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's2 (12.50)29.6817
2010's11 (68.75)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Tsikas, D1
Armstead, EA; Bayne, KV; Converso-Baran, KL; Cuttitta, AJ; D'Alecy, LG; Garbincius, JF; Merz, LE; Michele, DE; Schrade, S; Whitesall, SE1
Bollenbach, A; Bonati, U; Fischer, D; Hafner, P; Hanff, E; Kayacelebi, AA; Tsikas, D1
Bossi, L; de la Porte, S; Escolar, D; Fougerousse, F; Foutz, AS; Gillet, B; Haddad, H; He, X; Israël, M; Matecki, S; Perronnet, C; Roulot, M; Sebrié, C; Vaillend, C; Vianello, S; Voisin, V; Yu, H1
Benoit, E; Bich, C; Brunelle, A; Cancela, JM; Consolaro, F; de la Porte, S; Israël, M; Lanchec, E; Roulot, M; Touboul, D; Vianello, S1
Davies, KE; Robinson, N; Tinsley, J1
Dickson, G; Gait, MJ; Jarmin, SA; Lu-Nguyen, NB; Popplewell, L; Saleh, AF1
Beckmann, B; Carmann, C; Chobanyan-Jürgens, K; Hörster, I; Kayacelebi, AA; Köhler, C; Lücke, T; Schara, U; Tsikas, D; Weigt-Usinger, K1
Bieri, O; Bonati, U; Deuster, S; Erne, B; Fischer, D; Fischmann, A; Frank, S; Gloor, M; Gueven, N; Hafner, P; Neuhaus, C; Peters, T; Pohlman, U; Rubino, D; Rutz, E; Schmid, M; Sinnreich, M1
Deng, B; Gotoh, T; Nguyen, HX; Tidball, JG; Villalta, SA1
Barbin, IC; Ferretti, R; Marques, MJ; Oggian, DS; Santo Neto, H; Taniguti, AP1
Becker, M; Bossi, L; Cha, HJ; de la Porte, S; Escolar, DM; Farajian, V; Francia, D; Gernapudi, R; Gordish-Dressman, H; Guerron, AD; Hoffman, EP; Nagaraju, K; Pandey, GS; Partridge, T; Pistilli, E; Rawat, R; Sali, A; Spurney, CF; Zerr, P1
Chagneau, C; De La Porte, S; Laroche, S; Le Blanc, P; Mornet, D; Perronnet, C; Samson-Desvignes, N; Vaillend, C1
Beuve, A; Crassous, PA; Fraidenraich, D; Gonzalez, JP; Peluffo, RD; Ramachandran, J; Schneider, JS; Xie, LH; Zheng, R1
De La Porte, S; Gayraud, J; Hnia, K; Hugon, G; Matecki, S; Mornet, D; Ramonatxo, M1
Baux, G; Chaubourt, E; De La Porte, S; Fossier, P; Israël, M; Leprince, C1

Trials

4 trial(s) available for arginine and Becker Muscular Dystrophy

ArticleYear
Effects of single and combined metformin and L-citrulline supplementation on L-arginine-related pathways in Becker muscular dystrophy patients: possible biochemical and clinical implications.
    Amino acids, 2018, Volume: 50, Issue:10

    Topics: Adult; Amidinotransferases; Arginine; Citrulline; Creatinine; Dietary Supplements; Female; Glycine; Guanidinoacetate N-Methyltransferase; Homoarginine; Humans; Male; Metformin; Middle Aged; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitrates; Nitric Oxide Synthase Type I; Treatment Outcome; Young Adult

2018
Safety, tolerability, and pharmacokinetics of SMT C1100, a 2-arylbenzoxazole utrophin modulator, following single- and multiple-dose administration to healthy male adult volunteers.
    Journal of clinical pharmacology, 2015, Volume: 55, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Arginine; Benzothiazoles; Benzoxazoles; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Half-Life; Healthy Volunteers; Humans; Male; Middle Aged; Muscular Dystrophy, Duchenne; No-Observed-Adverse-Effect Level; Utrophin; Young Adult

2015
The L-arginine/NO pathway and homoarginine are altered in Duchenne muscular dystrophy and improved by glucocorticoids.
    Amino acids, 2015, Volume: 47, Issue:9

    Topics: Adolescent; Adult; Arginine; Child; Child, Preschool; Cross-Sectional Studies; Glucocorticoids; Homoarginine; Humans; Infant; Male; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitric Oxide; Pilot Projects

2015
Improved Muscle Function in Duchenne Muscular Dystrophy through L-Arginine and Metformin: An Investigator-Initiated, Open-Label, Single-Center, Proof-Of-Concept-Study.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Arginine; Biopsy; Child; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging; Metformin; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitric Oxide Synthase Type I; Pilot Projects

2016

Other Studies

12 other study(ies) available for arginine and Becker Muscular Dystrophy

ArticleYear
Determination of equilibria constants of arginine:glycine amidinotransferase (AGAT)-catalyzed reactions using concentrations of circulating amino acids.
    Amino acids, 2023, Volume: 55, Issue:2

    Topics: Amidinotransferases; Arginine; Catalysis; Citrulline; Homoarginine; Humans; Muscular Dystrophy, Duchenne

2023
Enhanced dimethylarginine degradation improves coronary flow reserve and exercise tolerance in Duchenne muscular dystrophy carrier mice.
    American journal of physiology. Heart and circulatory physiology, 2020, 09-01, Volume: 319, Issue:3

    Topics: Amidohydrolases; Animals; Arginine; Cardiomyopathies; Coronary Circulation; Disease Models, Animal; Exercise Tolerance; Female; Heterozygote; Male; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, Transgenic; Muscular Dystrophy, Duchenne; Myocardium; Necrosis; Quadriceps Muscle; Ventricular Function, Left

2020
Arginine butyrate: a therapeutic candidate for Duchenne muscular dystrophy.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:6

    Topics: Animals; Animals, Newborn; Arginine; Butyrates; Cells, Cultured; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Up-Regulation; Utrophin

2013
Low doses of arginine butyrate derivatives improve dystrophic phenotype and restore membrane integrity in DMD models.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2014, Volume: 28, Issue:6

    Topics: Animals; Arginine; Butyrates; Cell Membrane Permeability; Cells, Cultured; Disease Models, Animal; Histone Deacetylase Inhibitors; Humans; Male; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscle Strength; Muscles; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Utrophin

2014
Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2015, Volume: 23, Issue:8

    Topics: Alternative Splicing; Animals; Animals, Newborn; Arginine; Diaphragm; Disease Models, Animal; Dystrophin; Exons; Genetic Therapy; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Morpholinos; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Myostatin; Necrosis; Oligonucleotides, Antisense; Open Reading Frames; Peptides; Reading Frames

2015
Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy.
    Human molecular genetics, 2009, Feb-01, Volume: 18, Issue:3

    Topics: Animals; Arginine; Cell Proliferation; Cells, Cultured; Cytokines; Humans; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Nitric Oxide; Nitric Oxide Synthase Type II; Phenotype; Severity of Illness Index

2009
Myocardial fibrosis is unaltered by long-term administration of L-arginine in dystrophin deficient mdx mice: a histomorphometric analysis.
    Acta biologica Hungarica, 2010, Volume: 61, Issue:2

    Topics: Animals; Arginine; Cardiomyopathies; Dystrophin; Fibrosis; Inflammation; Male; Mice; Mice, Inbred mdx; Muscles; Muscular Dystrophy, Duchenne; Myocardium; Nitric Oxide; Time Factors

2010
Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy.
    PloS one, 2010, Jun-21, Volume: 5, Issue:6

    Topics: Animals; Arginine; Behavior, Animal; Butyrates; Disease Models, Animal; Drug Therapy, Combination; Female; Gene Expression Profiling; Gene Expression Regulation; Heart; Mice; Mice, Inbred mdx; Muscles; Muscular Dystrophy, Duchenne; Prednisone; RNA, Messenger; Time Factors; Utrophin

2010
Upregulation of brain utrophin does not rescue behavioral alterations in dystrophin-deficient mice.
    Human molecular genetics, 2012, May-15, Volume: 21, Issue:10

    Topics: Animals; Arginine; Brain; Butyrates; Dystrophin; Mice; Mice, Inbred mdx; Mice, Knockout; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; RNA, Messenger; Up-Regulation; Utrophin

2012
Nitric oxide signalling pathway in Duchenne muscular dystrophy mice: up-regulation of L-arginine transporters.
    The Biochemical journal, 2013, Jan-01, Volume: 449, Issue:1

    Topics: Amino Acid Transport Systems; Animals; Arginine; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Female; Male; Mice; Mice, Inbred mdx; Mice, Knockout; Mice, Transgenic; Muscular Dystrophy, Duchenne; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type I; Protein Transport; Signal Transduction; Up-Regulation; Utrophin

2013
L-arginine decreases inflammation and modulates the nuclear factor-kappaB/matrix metalloproteinase cascade in mdx muscle fibers.
    The American journal of pathology, 2008, Volume: 172, Issue:6

    Topics: Animals; Arginine; Inflammation; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred mdx; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Dystrophy, Duchenne; NF-kappa B; Nitric Oxide Synthase; Regeneration; Signal Transduction

2008
Nitric oxide and l-arginine cause an accumulation of utrophin at the sarcolemma: a possible compensation for dystrophin loss in Duchenne muscular dystrophy.
    Neurobiology of disease, 1999, Volume: 6, Issue:6

    Topics: Animals; Arginine; Cell Line; Cytoskeletal Proteins; Dystrophin; Hydroxyurea; Membrane Proteins; Mice; Mice, Inbred C57BL; Molsidomine; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Nitric Oxide; Nitric Oxide Donors; Utrophin

1999