arginine has been researched along with Alloxan Diabetes in 370 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 70 (18.92) | 18.7374 |
| 1990's | 116 (31.35) | 18.2507 |
| 2000's | 80 (21.62) | 29.6817 |
| 2010's | 80 (21.62) | 24.3611 |
| 2020's | 24 (6.49) | 2.80 |
| Authors | Studies |
|---|---|
| Kaur, G; Kumawat, VS | 2 |
| Inoue, Y; Iwai, M; Kadoyama, K; Matsumoto, K; Nitta, Y; Takano-Ohmuro, H; Takasugi, R; Takenokuchi, M; Taniguchi, T; Yoshida, K | 1 |
| Bomalaski, JS; DeBosch, BJ; Higgins, CB; Van Tine, BA; Zhang, Y | 1 |
| Beresewicz, A; Duda, M; Gajos-Draus, A | 1 |
| Allen, CL; Amoaku, W; Arkill, KP; Bates, DO; Batson, J; Horton, KL; Malhi, NK; Morris, JC; Riu, F; Stewart, E | 1 |
| Fu, Q; Gutman, J; Li, K; Liu, S; Zhu, A | 1 |
| Chen, F; Liao, J; Lu, Q; Niu, C; Wang, H; Wang, S; Yu, Y | 1 |
| Cao, Z; Chen, G; Guo, Y; Hu, X; Li, Y; Liu, X; Xu, Q; Zhang, Y | 1 |
| Abd El-Rady, NM; Gomaa, AMS; Gomaa, WMS; Hosny, A; Sayed, MM | 1 |
| Dang, LH; Dao, TP; Do, THT; Ha, PT; Nguyen, TP; Pham, TKT; Tran, NQ | 1 |
| Dzugkoev, SG; Dzugkoeva, FS; Khubulova, AE; Margieva, OI | 1 |
| Huang, CY; Jiang, JL; Li, G; Li, MY; Wu, MT; Xiong, XM; Zhou, T | 1 |
| Bode-Böger, SM; Brilloff, S; Hohenstein, B; Hugo, C; Jarzebska, N; Martens-Lobenhoffer, J; Rexin, A; Rodionov, RN; Schneider, A; Sradnick, J; Todorov, V; Weiss, N | 1 |
| Abdel-Rahman, AA; Leffler, KE | 1 |
| Awad, AS; Cooper, TK; Gao, T; Morris, SM; Stanley, K; Wetzel, MD | 1 |
| Abdel-Latif, Y; Badawy, E; El-Laithy, N; El-Naggar, M; El-Waseef, M; Hassan, H; Hussein, J | 1 |
| Aizawa, N; Fukuhara, H; Igawa, Y; Kume, H; Masuda, K; Okegawa, T; Watanabe, D | 1 |
| Baek, IH; Ha, ES; Hong, SH; Hwang, SJ; Jin Seo, H; Kim, JS; Kim, MS; Lee, S; Park, H | 1 |
| Atan, D; Barrington, AF; Butler, MJ; Coward, RJM; Graham, M; Heesom, KJ; Herbert, E; Hurcombe, JA; Ju, W; Kretzler, M; Lay, AC; Lewis, PA; McArdle, CA; Mountjoy, E; Nair, V; Neal, CR; Nelson, RG; Perrett, RM; Ramnath, RD; Satchell, SC; Welsh, GI; Wilson, MC | 1 |
| Engel, H; Gazyakan, E; Germann, G; Hirche, C; Reichenberger, MA; Urbach, O | 1 |
| He, YL; Qiu, N; Wei, XM; Xiong, Y; Zhang, ZJ; Zhou, XK | 1 |
| Feng, Y; Liu, Q; Liu, X; Lou, K; Ma, S; Meng, X; Song, X; Wang, C; Wang, W; Wang, X; Xu, H | 1 |
| Ikeda, H; Kamata, T; Kamei, J; Ueda, D; Waddington, JL; Yonemochi, N | 1 |
| Li, Y; Liu, DF; Mei, X; Qiu, P; Tang, MW; Yang, HL; Zeng, J; Zhao, Y | 1 |
| He, YL; Li, XM; Nie, F; Xiong, Y; Zhou, XK | 1 |
| Buzadzic, B; Filipovic, M; Ivanovic-Burmazovic, I; Jankovic, A; Korac, A; Korac, B; Masovic, S; Otasevic, V; Stancic, A | 1 |
| Cao, J; Lei, T; Liu, S; Lu, Z; Shi, L; Wang, H; Zhao, C | 1 |
| Bulani, Y; Sharma, SS | 1 |
| He, ZM; Lei, YP; Lin, Y; Lu, CW; Wang, L; Xiong, Y | 1 |
| Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP | 1 |
| Bensellam, M; Cantley, J; Chan, JY; Dezaki, K; Grey, ST; Gurzov, EN; Herzog, H; Ip, CK; Kay, TW; Laybutt, DR; Lee, K; Loh, K; Nakata, M; Shi, YC; Thomas, HE; Waibel, M; Walters, S; Yada, T | 1 |
| Lotfipour, S; Smith, MT | 1 |
| El-Banna, M; El-Naggar, ME; Hussein, J; Razik, TA | 1 |
| Atawia, RT; Bagi, Z; Bhatta, A; Caldwell, RB; Caldwell, RW; Chen, J; Fouda, AY; Lucas, R; Toque, HA; Xu, Z; Yao, L | 1 |
| Bode-Böger, SM; Brilloff, S; Heinrich, A; Hohenstein, B; Hugo, CPM; Jarzebska, N; Martens-Lobenhoffer, J; Rodionov, RN; Todorov, VT; Weiss, N | 1 |
| Cong, XD; Jin, SJ; Li, Q; Li, XX; Su, J; Wei, W; Xu, M | 1 |
| Du, MR; Jiang, JL; Li, NS; Wang, YJ; Yan, L; Zhou, T | 1 |
| Fu, Q; Hu, LL; Tian, T; Zhang, H; Zhang, KQ | 1 |
| Ahmed, SM; Ragy, MM | 1 |
| Ali, O; El-Naggar, M; El-Toukhy, S; Harvy, M; Hussein, JS; Nabeeh, M; Raafat, J; Ramzy, T; Rasheed, W | 1 |
| Liu, YT; Mong, MC; Pai, PY; Wang, ZH; Yang, YC; Yin, MC | 1 |
| Cheng, YS; Cong, XD; Dai, DZ; Dai, Y; Peng, HJ; Shi, FH | 1 |
| Ai, J; Cai, BZ; Chen, QX; Liu, J; Sun, LH; Wang, N; Xie, F; Yang, BF; Ye, JH | 1 |
| Arvindekar, AU; Haldavnekar, VS; Joglekar, MM; Panaskar, SN; Taklikar, SS | 1 |
| Cong, XD; Dai, DZ; Dai, Y; Shi, FH; Wu, Y; Zhang, YM | 1 |
| Cong, XD; Dai, DZ; Dai, Y; Ding, MJ; Liu, GL; Zhang, YM | 1 |
| Chen, X; Deng, M; He, P; Liu, H; Pang, X; Tang, Z; Yang, Y | 1 |
| Ai, J; Niu, HF; Xie, F; Xu, L; Yan, Y; Yang, BF | 1 |
| Albertoni Borghese, MF; Balonga, S; Bustamante, J; Cicerchia, D; Filipuzzi, AL; Lavagna, A; Lores-Arnaiz, S; Majowicz, M; Ortiz, Mdel C | 1 |
| Borthwick, G; Cairns, C; Choudhary, AK; Conway, BR; Hughes, J; Kluth, D; Morton, NM; Rennie, J | 1 |
| Dzugkoev, SG; Dzugkoeva, FS; Metel'skaya, VA | 1 |
| Hotta, Y; Kataoka, T; Kimura, K; Maeda, Y | 1 |
| Chang, CY; Chang, KC; Chang, RW; Chen, YS; Ko, WJ; Ko, YH; Tsai, PR; Wang, CH; Wang, SS; Young, TH | 1 |
| Fasching, A; Hansell, P; Palm, F; Persson, P; Teerlink, T | 2 |
| Khalili, A; Khosravi, MB; Nekooeian, AA | 1 |
| Chennupati, R; De Mey, JG; Janssen, BJ; Köhler, SE; Lamers, WH; Marion, V; Meens, MJ | 1 |
| Albertoni Borghese, MF; Balonga, SE; Costa, MA; Elesgaray, R; Filipuzzi, AL; Lavagna, A; Majowicz, MP; Ortiz, MC | 1 |
| Awad, AS; Cooper, TK; Gao, T; Morris, SM; You, H | 1 |
| El-Maraghy, SA; Mehana, NA | 1 |
| Farsi, L; Keshavarz, M; Kharazmi, F; Rezaei, S; Soltani, N | 1 |
| Nevo, E; Sybirna, NO; Wasser, SP; Yurkiv, B | 1 |
| Behrmann, A; Bello Arredondo, Y; Brill, LM; Cheng, SL; Kapoor, K; Kovacs, A; Krchma, K; Mead, M; Perera, R; Ramachandran, B; Shao, JS; Smith, C; Towler, DA; Williams, BO | 1 |
| Devi, VG; Preetha, PP; Rajamohan, T | 1 |
| Ho, JJ; Hsu, CC; Hsu, JY; Yang, HT; Yin, MC | 1 |
| Düfer, M; García-López, PM; Gurrola-Díaz, CM; Vargas-Guerrero, B; Wiedemann, M; Wink, M | 1 |
| Bhatta, A; Cain, M; Caldwell, RB; Caldwell, RW; Chutkan, N; Elsalanty, M; Fulzele, S; Howie, N; Hunter, M; Isales, C; Kolhe, R; Sangani, R; Shinde, R; Toque, HA; Wong, A; Yao, L | 1 |
| Cong, XD; Dai, DZ; Dai, Y; Hu, C; Khan, HH; Li, Q; Shi, FH; Xu, M | 1 |
| Abd-Alkhalek, HA; El-Bakly, WM; El-Lithy, GM; Hamza, M; Masoud, SI; Matboli, M | 1 |
| Buzadzic, B; Ferreri, C; Filipovic, M; Ivanovic-Burmazovic, I; Jankovic, A; Korac, A; Korac, B; Otasevic, V; Stancic, A | 1 |
| Carpinelli, AR; Carvalho, DS; Cavanal, MF; da Silva Alves, E; Diniz, MM; Gil, FZ; Haidar, AA; Hirata, AE | 1 |
| Almeida, RM; Alves, EO; Amorin, R; Barros, AD; Bocca, AL; Borin, MF; Cavalcanti, FF; Jerônimo, MS; MoritaI, VE; Nóbrega, YK; Souza, NL | 1 |
| Gonon, AT; Kiss, A; Pernow, J; Sjöquist, PO; Tratsiakovich, Y; Yang, J | 1 |
| Andreatini, R; Bortolanza, M; da Cunha, JM; Del Bel, EA; Frazão Vital, MAB; Siba, IP; Zanoveli, JM | 1 |
| Bhatnagar, A; Kaiserova, K; Ramana, KV; Srivastava, SK; West, MB | 1 |
| Lin, CC; Yin, MC | 1 |
| Abramov, AV; Kamyshnyĭ, OM; Kolesnyk, IuM | 1 |
| Ferentc, M; Gzregotsky, M; Urbanovych, A; Yaschenko, A; Zayachkivska, O | 1 |
| Dixit, PV; Jain, NS; Kochar, NI; Umathe, SN | 1 |
| Baiza-Gutman, LA; Barrera-Escorcia, E; Chirino-Galindo, G; Palomar-Morales, M | 1 |
| Ford, EL; Herrera, PL; Hu, J; Kawamori, D; Kulkarni, RN; Kurpad, AJ; Liew, CW; McGuinness, OP; Polonsky, KS; Shih, JL | 1 |
| Clementi, G; Fiore, CE; Luca, T; Mangiafico, RA; Martinez, G; Muratore, F; Pennisi, P; Prato, A; Pulvirenti, I | 1 |
| Chen, Y; Gu, Q; Sheng, M; Xu, X; Zhang, X; Zheng, Z | 1 |
| Feng, M; Guo, Z; He, ZM; Lu, CW; Wu, ZZ; Xiong, Y | 1 |
| Chaudhuri, BS; Ray, M; Ray, S; Talukdar, D | 1 |
| Baker, A; Balestrieri, ML; Cacciatore, F; D'Armiento, FP; de Nigris, F; De Rosa, G; Farzati, B; Feng, Q; Fiorito, C; Giordano, A; Giovane, A; Ignarro, LJ; Lanza, R; Lu, SJ; Mancini, FP; Minucci, PB; Napoli, C; Pagliarulo, C; Pastore, L; Rengo, F; Rienzo, M; Salvatore, F; Servillo, L; Testa, G; Williams-Ignarro, S | 1 |
| Arellano-Mendoza, MG; Castorena-Torres, F; Coronel, I; del Valle-Mondragon, L; Escalante, B; Rios, A; Romo, E; Vargas-Robles, H | 1 |
| Brasacchio, D; Chin-Dusting, J; Cooper, ME; Coughlan, MT; Forbes, JM; Harris, E; Kaye, D; Paavonen, K; Soro-Paavonen, A; Thomas, MC; Tong, DC; Venardos, K; Zhang, WZ | 1 |
| García-Salcedo, JA; Morales, S; Muñoz-Torres, M | 1 |
| Huang, KH; Pai, MH; Wu, CH; Yeh, SL | 1 |
| Buzadzić, B; Dinulović, I; Janković, A; Korać, A; Korać, B; Petrović, V; Vasilijević, A; Vojcić, Lj | 1 |
| Agostini, C; Albiero, M; Avogaro, A; Boscaro, E; Cosma, C; Fadini, GP; Giorgio, M; Iori, E; Lapolla, A; Menegazzo, L; Pagnin, E; Pelicci, PG; Pengo, V; Stendardo, M | 1 |
| Clementi, G; Fiore, CE; Loreto, C; Martinez, G; Musumeci, G | 1 |
| Abe, T; Hishinuma, T; Saigusa, D; Shiba, K; Suzuki, N; Takahashi, M; Tanaka, S; Tomioka, Y | 1 |
| Heidarianpour, A | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K; Takenouchi, Y | 1 |
| Brodiak, IV; Hnatush, AR; Sybirna, NO | 1 |
| Arya, A; Sharma, PL; Yadav, HN | 1 |
| Fartushok, NV; Fedevych, IuM; Khavrona, OP; Skliarov, OIa; Sol's'ki, Ia | 1 |
| Chen, MS; Chen, N; Leng, YP; Luo, JD; Xiong, Y; Xu, WJ | 1 |
| Chetyrkin, S; Hachey, DL; Hudson, B; Madu, H; Mathis, M; McDonald, WH; Pedchenko, V; Sanchez, OA; Stec, D; Voziyan, P | 1 |
| Ader, M; Bunnell, DJ; Harlan, DM; Hirshberg, B; Remaley, AT; Rickels, MR; Rother, KI; Soleimanpour, SA; Sumner, AE | 1 |
| Nevin, KG; Rajamohan, T; Salil, G | 2 |
| Lin, CY; Yin, MC | 1 |
| Breuillard, C; Curis, E; Cynober, L; Darquy, S; De Bandt, JP; Garnier, JP; Neveux, N | 1 |
| Arend, A; Aunapuu, M; Avolio, AP; Butlin, M; Eha, J; Kals, J; Kampus, P; Põdramägi, T; Salum, E; Zilmer, M | 1 |
| Câmara, NO; Cavanal, MF; Correa-Costa, M; De Marco, DT; Gil, FZ; Hirata, AE; Landgraf, MA; Semedo, P; Vieira, DA | 1 |
| Cheng, H; Fan, X; Harris, RC; Paueksakon, P; Wang, H | 1 |
| Kumar, PH; Murugan, PS; Puhari, SS; Ramprasath, T; Selvam, GS; Vasudevan, V | 1 |
| Andreeva, LA; Grigorieva, ME; Ljapina, LA; Myasoedov, NF; Shubina, TA | 1 |
| Fukami, K; Ishibashi, Y; Maeda, S; Matsui, T; Nishino, Y; Ojima, A; Takeuchi, M; Yamagishi, S | 1 |
| Bidasee, KR; Kutty, S; Moore, CJ; Nagai, R; Shao, CH; Singh, J | 1 |
| Adimoolam, S; Asagami, T; Cooke, JP; Ito, A; Kimoto, M; Lin, KY; Reaven, GM; Tsao, PS; Tsuji, H | 1 |
| Kamata, K; Makino, A | 1 |
| Coppey, LJ; Davidson, EP; Gellett, JS; Yorek, MA | 1 |
| Kashiwagi, A; Kim, H; Koya, D; Maeda, K; Sasaki, T; Yasuda, H | 1 |
| Gu, Y; Hiura, A; Hori, H; Inoue, K; Sakurai, T; Sumi, S; Tabata, Y; Wang, W | 1 |
| Fu, SH; Fu, YF; Xiong, Y; Zhou, HH | 1 |
| Li, Q; Miller, B; Perlman, I; Zemel, E | 1 |
| Sadan, G; Tasatargil, A | 1 |
| Gai, W; Gleichmann, H; Schott-Ohly, P; Schulte im Walde, S | 1 |
| Haynes, TE; Kohli, R; Meininger, CJ; Self, JT; Wu, G; Yan, W | 1 |
| Ben-Dor, A; Benedict, Y; Blum, M; Brasowski, E; Chernichovski, T; Iaina, A; Levo, Y; Misonzhnik, F; Schwartz, D; Schwartz, IF; Wollman, Y | 1 |
| Beffy, P; Bezzi, D; Gross, R; Lajoix, AD; Marchetti, P; Masiello, P; Novelli, M; Pocai, A | 1 |
| Klahr, S; Morrissey, J | 1 |
| Mariño, G; Míguez, I; Rodríguez, B; Taboada, C | 1 |
| Ge, K; Liao, ZJ; Lu, SL; Niu, YW; Qing, C; Rong, L; Shi, JX; Wang, MJ; Xie, T | 1 |
| Bilbao, G; Contreras, JL; Eckhoff, DE; Eckstein, C; Fernández, JA; Griffin, JH; Ringland, SE; Smyth, CA; Thompson, JA; Vilatoba, M; Young, C | 1 |
| Chen, KM; Lee, SH; Liu, CT; Tsai, LJ | 1 |
| Fu, S; Fu, Y; Lei, M; Xiong, Y | 1 |
| Kotsiuruba, AV; Prysiazhna, OD; Sahach, VF; Tkachenko, MN | 1 |
| Hernández, Rde H; Méndez, JD | 1 |
| Ge, K; Li, WD; Lu, SL; Niu, YW; Qing, C; Shu, L; Wang, MJ; Xie, T | 1 |
| Cerasi, E; Efendic, S; Kaiser, N; Nesher, R; Oprescu, A | 1 |
| Anjaneyulu, M; Chopra, K; Singal, A | 1 |
| Buerk, DG; Carlsson, PO; Hansell, P; Liss, P; Palm, F | 1 |
| Carr, RD; Gotfredsen, CF; Larsen, MO; Pørksen, N; Rolin, B; Sturis, J; Wilken, M | 1 |
| Balderas, FL; Méndez, JD | 1 |
| Alexandru, N; Constantinescu, E; Georgescu, A; Popov, D | 1 |
| Fujii, K; Marumo, K; Mori, Y; Saito, M | 1 |
| Hu, CP; Jiang, JL; Li, YJ; Wang, S; Yang, DL; Zhang, XJ | 1 |
| Caldwell, RB; Caldwell, RW; El-Remessy, AB; Ma, G; Matragoon, S; Tawfik, HE | 1 |
| Nagaraj, RH; Padival, S | 1 |
| Lei, ST; Lü, WM; Shi, HP; Wang, SM; Zhang, Q; Zhang, YJ | 1 |
| Deng, HW; Deng, S; Jia, SJ; Li, D; Li, YJ; Wang, L; Xia, K; Yang, ZC; Zhang, XH; Zhang, Z | 1 |
| Beals, JM; DiMarchi, RD; Kahl, SD; Kohn, WD; Li, S; Mayer, JP; Micanovic, R; Myers, SL; Shang, J; Strifler, BA; Vick, AM; Zhang, L | 1 |
| Auge, N; Ayala, V; Cantero, AV; Elbaz, M; Nègre-Salvayre, A; Pamplona, R; Portero-Otín, M; Salvayre, R; Sanson, M; Thiers, JC | 1 |
| El-Bab, MF; Gawad, HS; Hammad, LN; Mohamadin, AM | 1 |
| Cavanal, Mde F; Fortes, ZB; Forti, AL; Franco, Mdo C; Gil, FZ; Gomes, GN; Rocha, SO | 1 |
| Joharchi, K; Jorjani, M | 1 |
| Brownlee, M; Edelstein, D; Giardino, I; Hammes, HP; Matsumura, T; Pestell, R; Rabbani, N; Sarthy, VP; Suske, G; Taguchi, T; Thornalley, PJ; Yao, D | 1 |
| Buzadzic, B; Jankovic, A; Korac, A; Korac, B; Petrovic, V; Vasilijevic, A | 1 |
| Beckmann, B; Chobanyan, K; Gutzki, FM; Mitschke, A; Stichtenoth, DO; Suchy, MT; Thum, T; Tsikas, D; Zhu, B | 1 |
| Dolber, PC; Fraser, MO; Yang, Z | 1 |
| Bartoli, M; Caldwell, RB; Caldwell, RW; El-Remessy, AB; Labazi, M; Platt, DH; Romero, MJ; Tawfik, HE | 1 |
| Izuhara, Y; Miyata, T; Nangaku, M; Ohtomo, S; Strihou, Cv; Takizawa, S | 1 |
| Chernichovsky, T; Davidovitch, A; Iaina, A; Levin-Iaina, N; Schwartz, D; Schwartz, I | 1 |
| Hernández-Espinosa, C; Salceda, R; Sánchez-Chávez, G | 1 |
| Brodiak, IV; Sybirna, NO | 1 |
| Debaveye, Y; Ellger, B; Langouche, L; Richir, M; Teerlink, T; Van den Berghe, G; Van Leeuwen, PA; Vanhorebeek, I | 1 |
| Baba, S; Hirose, Y; Ishihara, K; Kazumi, T; Makimura, H; Utsumi, M; Yoshino, G | 1 |
| Chiba, T; Fujita, T; Goto, Y; Kadowaki, S; Matsukura, S; Nozawa, M; Seino, Y; Taminato, T | 2 |
| Berelowitz, M; Frohman, LA; Goto, Y | 1 |
| Bonner-Weir, S; Clore, ET; Weir, GC; Zmachinski, CJ | 1 |
| Hermansen, K | 1 |
| Kumahara, Y; Ota, T; Sawazaki, N; Shima, K; Tabata, M; Tanaka, A; Tanaka, R | 1 |
| Efendić, S; Grill, V | 1 |
| Engerman, RL; Kern, TS | 2 |
| Patel, YC; Ruggere, MD | 1 |
| Frankel, BJ; Gerritsen, GC; Grodsky, GM; Heldt, AM | 1 |
| Bonner-Weir, S; Leahy, JL; Weir, GC | 3 |
| Kondo, M; Nakamura, Y; Nakano, K; Yoshida, T | 1 |
| Bailbe, D; Giroix, MH; Kergoat, M; Picon, L; Portha, B | 1 |
| Grill, V; Herberg, L | 1 |
| Marliss, EB; Nakhooda, AF; Poussier, P | 1 |
| Allen, LH; Wood, RJ | 1 |
| Gotoh, M; Monden, M; Okamura, J; Shima, K | 1 |
| Honey, RN; Mathe, CJ; Schwarz, JA; Weir, GC | 1 |
| Giroix, MH; Kergoat, M; Picon, L; Portha, B | 2 |
| Goto, Y; Kakizaki, M; Kimura, K; Kudo, M; Takebe, K; Toyota, T | 1 |
| Phillips, RW; Spangler, RS | 1 |
| Grose, M; Marliss, EB; Nakhooda, AF; Poussier, P | 1 |
| Campbell, J; Pierluissi, J | 1 |
| Kobayashi, T; Nihei, J; Nishikawa, K; Ohneda, A | 1 |
| Funahashi, M; Kato, H; Nakagawa, H; Shiosaka, S | 1 |
| Bhathena, SJ; Recant, L; Smith, SS; Wilkins, SD | 1 |
| Frankel, BJ; Grodsky, GM; Heldt, AM | 1 |
| Cabo, J; Gomez, M; Grisolía, S; Jordá, A | 1 |
| Glance, SD; Hodgson, WC; James, GM; King, RG; Sikorski, BW | 1 |
| Craven, PA; DeRubertis, FR; Studer, RK | 1 |
| Brown, DM; Mauer, SM; Raij, L; Shultz, PJ; Tolins, JP | 1 |
| Efendic, S; Jansson, L; Ostenson, CG; Sandler, S; Svensson, AM | 1 |
| Bjerre, U; Mandrup-Poulsen, T; Nerup, J; Reimers, JI | 1 |
| Ansite, JD; Lokeh, A; Mills, CD; Rossini, TJ; Stevens, RB; Sutherland, DE | 1 |
| Martinez-Cuesta, MA; Massuda, H; Moncada, S; Whittle, BJ | 1 |
| Kihara, M; Low, PA | 1 |
| Kasuga, A; Maruyama, T; Miyazaki, J; Nakaki, T; Ozawa, Y; Saruta, T; Takayama, S; Takei, I | 1 |
| Chang, K; Corbett, JA; Currie, MG; Hasan, KS; McDaniel, ML; Misko, TP; Moore, WM; Petrash, JM; Smith, SR; Tilton, RG | 1 |
| Davison, JS; Mathison, R | 1 |
| Abiru, T; Endo, K; Kamata, K; Kasuya, Y; Machida, H | 1 |
| Kimura, I; Kimura, M; Nakashima, N | 1 |
| Catanzaro, OL; Dominguez, A; Hope, SI; Marina-Prendes, MG; Zuccollo, A | 1 |
| Carmines, PK; Ohishi, K | 1 |
| Peltier, BA; Pieper, GM | 1 |
| Mancusi, G; Raberger, G; Schütz, W; Sexl, V | 1 |
| Poston, L; Taylor, PD | 1 |
| Ansite, JD; Brown, RR; Lokeh, A; Mills, CD; Saxena, M; Stevens, RB; Sutherland, DE | 1 |
| Hirose, H; Ito, K; Kido, K; Koyama, K; Maruyama, H; Saruta, T; Tashiro, Y | 1 |
| Allen, TJ; Cooper, ME; Komers, R | 1 |
| Hara, M; Sasaki, H; Takahashi, K; Yamatani, K | 1 |
| Ansite, JD; Lokeh, A; Mills, CD; Saxena, M; Stevens, RB; Sutherland, DE | 1 |
| Oon, BB; Poston, L; Taylor, PD; Thomas, CR | 1 |
| Davis, EA; Haynes, JM; Hodgson, WC; James, GM | 1 |
| Dananberg, J; Feldman, EL; Greene, DA; Kamijo, M; Lattimer, SA; Shindo, H; Sima, AA; Stevens, MJ; Thomas, TP | 1 |
| Dai, FX; Diederich, A; Diederich, D; Skopec, J | 1 |
| Iwamoto, Y; Kamei, J; Kasuya, Y; Misawa, M; Nagase, H | 1 |
| Imura, H; Ishida, H; Kato, S; Kurose, T; Okada, Y; Okamoto, Y; Seino, Y; Taminato, T; Tsuji, K; Tsuura, Y | 1 |
| Mayhan, WG | 2 |
| Hodgson, WC; King, RG; Sikorski, BW | 1 |
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| Blum, M; Cabili, S; Chernihovsky, T; Goor, Y; Iaina, A; Peer, G; Silverberg, D; Wollman, Y | 1 |
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| Carrington, AL; Dewhurst, M; Omawari, N; Stevens, EJ; Tomlinson, DR; Vo, PA | 1 |
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| Angulo, J; Marín, J; Neira, M; Peiró, C; Rodríguez-Mañas, L; Sánchez-Ferrer, CF | 1 |
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| Baynes, JW; Degenhardt, TP; Fu, MX; Neidlein, R; Reiff, K; Reiter, R; Strein, K; Thorpe, SR; Voss, E | 1 |
| Goto, K; Ishige, A; Kamei, J; Komatsu, Y; Suzuki, Y | 1 |
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| Elías, MM; García, VM; Ochoa, JE | 1 |
| Bertuzzi, F; Di Carlo, V; Leone, BE; Nano, R; Piemonti, L; Pozza, G; Socci, C | 1 |
| Granstam, E; Granstam, SO | 1 |
| Altan, VM; Dinçer, D; Meral, S; Ozçelikay, AT; Tay, A; Yildizoğlu-Ari, N | 1 |
| Cartledge, J | 1 |
| Khan, MA; Mikhailidis, DP; Morgan, RJ; Thompson, CS | 1 |
| Altan, VM; Dinçer, UD; Güner, S; Ozçelikay, AT; Taşyaran, V; Tay, A; Yildizoğlu-Ari, N | 1 |
| Fu, P; Huang, S; Li, X; Zhang, X | 1 |
| Gür, S; Karahan, ST; Oztürk, B | 1 |
| Carmo, A; Carvalho, AP; Cunha-Vaz, JG; Lopes, MC | 2 |
| Dincer, UD; Ozcelikay, AT; Yilmaz, ED | 1 |
| Cenuse, M; Costache, G; Georgescu, A; Jinga, VV; Popov, D; Simionescu, M | 1 |
| Komori, T; Nanbu, A; Nishimura, M; Ohtsuka, K; Takahashi, H; Yoshimura, M | 1 |
| Chang, CJ; Cheng, JT; Chi, TC; Chin, WT; Juang, SW; Yu, WJ | 1 |
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| Berrino, L; D'Amico, M; De Angelis, L; Di Filippo, C; Giugliano, D; Marfella, R; Nappo, F; Rossi, F | 1 |
| Balderas, F; Méndez, JD | 1 |
| Aoyagi, K; Araki, E; Gotoh, T; Mori, M; Oyadomari, S; Shichiri, M | 1 |
| Bakala, H; Depreux, P; Fourmaintraux, E; Schwedler, SB; Striker, GE; Striker, LJ; Verbeke, P; Vilar, J; Weiss, MF | 1 |
| Adeghate, E; El-Sharkawy, T; Parvez, H; Ponery, AS | 1 |
| Babaya, N; Hamada, Y; Ikegami, H; Kawaguchi, Y; Nojima, K; Ogihara, T; Shibata, M; Ueda, H; Yamada, K; Yamato, E | 1 |
| Ahrén, B; Havel, PJ; Taborsky, GJ | 1 |
| Coppey, LJ; Davidson, EP; Dunlap, JA; Gellett, JS; Yorek, MA | 1 |
| Carr, RD; Gotfredsen, CF; Larsen, MO; Rolin, B; Svendsen, O; Wilken, M | 1 |
| Beck-Nielsen, H; Nielsen, TB; Yderstraede, KB | 1 |
| Biemel, KM; Lederer, MO; Mally, A; Nagaraj, RH; Padayatti, PS; Sarkar, P | 1 |
| Brodsky, SV; Chen, J; Goligorsky, DM; Goligorsky, MS; Gross, SS; Hampel, DJ; Li, H | 1 |
| Gajdosík, A; Gajdosíkova, A; Okruhlicova, L; Sotníkova, R; Stefek, M; Tribulova, N; Weismann, P | 1 |
| Christensen, SE; Hermansen, K; Orskov, H | 1 |
| Gerich, J; Hara, M; Patton, G | 1 |
| Kobayashi, T; Nihei, J; Ohneda, A; Sakai, T; Sanoyama, K; Umezu, M | 2 |
| Lund, ED; Lykkelund, C | 1 |
| Campbell, J; Green, GR; Pierluissi, J | 1 |
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| Epstein, G; Fanska, R; Grodsky, GM | 1 |
| Blazquez, E; Dobbs, RE; Muñoz-Barragan, L; Patton, GS; Unger, RH | 1 |
| Baetens, D; Dobbs, R; Faloona, G; Orci, L; Sakurai, H; Sasaki, H; Unger, R; Valverde, I | 1 |
| Dobbs, R; Unger, RH; Valverde, I | 1 |
| Cohen, RA; Gupta, S; McArthur, CS; Ruderman, NB; Sussman, I; Tornheim, K | 1 |
| Kolb, H; Kolb-Bachofen, V | 1 |
| Brain, SD; Lawrence, E | 1 |
| Faraci, FM; Fujii, K; Heistad, DD | 1 |
| Langenstroer, P; Mei, DA; O'Rourke, ST; Pieper, GM | 1 |
| McCarthy, AL; Poston, L; Taylor, PD; Thomas, CR | 1 |
| Höger, H; Lubec, B; Lubec, G; Szalay, S; Weninger, M; Xi, Z | 1 |
| Arreola, MA; Méndez, JD | 1 |
| Finegood, DT; Lewis, JT; Rajotte, RV; Tobin, BL; Tobin, BW | 1 |
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| Hisatomi, A; Inoue, K; Nawata, H; Umeda, F | 1 |
| Albrecht, RF; Miletich, DJ; Pelligrino, DA | 1 |
| Langenstroer, P; Pieper, GM | 1 |
| Kiesel, U; Kolb, H; Kolb-Bachofen, V; Kröncke, KD | 1 |
| Hertelendy, ZI; Patel, DG; Skau, KA | 1 |
| Mayhan, WG; Sharpe, GM; Simmons, LK | 1 |
| Chan, WL; Liew, FY; Lukic, ML; Ostojic, N; Stosic-Grujicic, S | 1 |
| Hirata, Y; Inoue, Y; Matsumoto, H; Mochizuki, N; Tasaka, Y | 1 |
| Bennett, T; Compton, AM; Gardiner, SM; Kiff, RJ | 2 |
| Campbell, IL; Harrison, LC; Oxbrow, L | 1 |
| Leahy, JL; Weir, GC | 2 |
| Efendic, S; Grill, V; Ostenson, CG | 1 |
| Bailbé, D; Blondel, O; Portha, B; Serradas, P | 1 |
| Bailbé, D; Giroix, MH; Goto, Y; Portha, B; Serradas, P; Suzuki, K | 1 |
| Bonner-Weir, S; Kahn, SE; Koerker, DJ; McCulloch, DK; Palmer, JP | 1 |
| Inoue, S; Nagase, H; Saitoh, T; Takamura, Y; Tanaka, K | 1 |
| Cattral, MC; Jaspan, JL; Kneteman, NM; Rajotte, RV; Scharp, DW; Warnock, GL | 1 |
| Kato, Y; Kawaguchi, M; Ohguni, S; Tanigawa, K | 1 |
| Hasegawa, G; Kanatsuna, T; Kitagawa, Y; Kondo, M; Mori, H; Nakano, K; Sawada, M; Shigeta, H; Takagi, S | 1 |
| Gillies, MC; Mandel, TE | 1 |
| Blech, W; Brömme, HJ; Hahn, HJ; Hildebrandt, W; Lucke, S | 1 |
| Ahrén, B; Alumets, J; Ar'Rajab, A; Bengmark, S | 1 |
| Ahrén, B; Ar'Rajab, A; Bengmark, S | 1 |
| Baba, S; Ohki, A; Okabayashi, Y; Otsuki, M; Tani, S | 1 |
| Bailbé, D; Portha, B; Serradas, P | 1 |
| Gross, R; Loubatières-Mariani, MM; Puech, R; Ribes, G; Zerbib, A | 1 |
| Sanda, M | 1 |
| Bond, JS; Spolarics, Z | 1 |
| Hermansen, K; Orskov, H; Schmitz, O | 1 |
| Eto, M; Ishii, K; Iwashima, Y; Morikawa, A; Takebe, T; Watanabe, K | 1 |
| Carloni, C; Cristallini, S; Filipponi, P; Gregorio, F; Gubbiotti, G; Pippi, R | 1 |
| White, MF | 1 |
| Blayac, JP; Loubatières-Mariani, MM; Ribes, G; Zerbib, A | 1 |
| Besmond, C; Darquy, S; Dreyfus, JC; Kahn, A; Munnich, A; Reach, G; Vaulont, S | 1 |
| Beard, JC; Benson, EA; Bergman, RN; Johnston, C; Kahn, SE; Klaff, LJ; Koerker, DJ; McCulloch, DK; Raghu, PK; Ward, WK | 1 |
| Cuthbertson, RA; Mandel, TE | 1 |
| Bailbe, D; Kergoat, M; Portha, B | 1 |
| Hashimoto, N; Horie, H; Iwaoka, H; Kanatsuka, A; Makino, H; Sakurada, M; Yoshida, S | 1 |
| DeFronzo, RA; Rossetti, L; Shulman, GI; Zawalich, W | 1 |
| Kajiyama, S; Kanatsuna, T; Kano, Y; Kitagawa, Y; Kondo, M; Mori, H; Nakamura, N; Nakano, K | 1 |
| Cristallini, S; Ferrandina, C; Filipponi, P; Gregorio, F; Nicoletti, I; Santeusanio, F | 1 |
| Giroix, MH; Kergoat, M; Portha, B | 1 |
| Alam, T; Baetens, D; Crider, B; Inman, L; Johnson, JH; Komiya, I; McCorkle, K; Moltz, J; Stefan, Y; Tominaga, M | 1 |
| Kergoat, M; Portha, B | 1 |
| Haynes, SP; Prowse, SJ; Wilson, JD | 1 |
| Dalstein, JM; Loubatieres-Mariani, MM; Ribes, G; Valette, G | 1 |
5 review(s) available for arginine and Alloxan Diabetes
| Article | Year |
|---|---|
[Pentosidine: a new biomarker in diabetes mellitus complications].
Topics: Animals; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Glycation End Products, Advanced; Glycosylation; Humans; Hypoglycemic Agents; Inflammation; Lysine; Oxidative Stress; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2011 |
L-arginine as a therapeutic tool in kidney disease.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Humans; Kidney Diseases; Nitric Oxide; Prognosis; Rats; Renal Circulation; Risk Assessment; Treatment Outcome; Up-Regulation | 2004 |
Nitric oxide: a pathogenetic factor in autoimmunity.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Autoimmunity; Calcium; Cell Adhesion; Cell Death; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Enzyme Induction; Humans; Inflammation; Islets of Langerhans; Isoenzymes; Macrophage Activation; Mice; Neutrophils; Nitric Oxide; Nitric Oxide Synthase | 1992 |
Experimental reduction of B-cell mass: implications for the pathogenesis of diabetes.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Synergism; Glucagon; Glucose; Glucose Tolerance Test; Histocytochemistry; Humans; Immunologic Techniques; In Vitro Techniques; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Pancreatectomy; Rats; Rats, Inbred Strains | 1986 |
The transport of cationic amino acids across the plasma membrane of mammalian cells.
Topics: Amino Acids; Animals; Arginine; Binding Sites; Biological Transport, Active; Cations; Cell Line; Cell Membrane; Cell Membrane Permeability; Diabetes Mellitus, Experimental; Glucagon; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Neoplasms, Experimental; Lysine; Mammals; Models, Biological; Ornithine; Rats; Sodium; Streptozocin; Substrate Specificity; Urea | 1985 |
365 other study(ies) available for arginine and Alloxan Diabetes
| Article | Year |
|---|---|
Cannabinoid 2 receptor agonist and L-arginine combination attenuates diabetic cardiomyopathy in rats via NF-ĸβ inhibition.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Down-Regulation; Drug Therapy, Combination; Male; NF-kappa B; Oxidative Stress; Polycyclic Sesquiterpenes; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Streptozocin | 2022 |
In Vitro and In Vivo Antiglycation Effects of Connarus ruber Extract.
Topics: Animals; Arginine; Collagen; Connaraceae; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Guanidines; Lipids; Lysine; Pyruvaldehyde; Rats; Streptozocin | 2022 |
Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism.
Topics: Animals; Arginine; Autophagy; Beclin-1; Dependovirus; Diabetes Mellitus, Experimental; Diet, Western; Dyslipidemias; Energy Metabolism; Fatty Liver; Fibroblast Growth Factors; Glucose; Hepatocytes; Homeostasis; Hydrolases; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Polyethylene Glycols; Thermogenesis | 2022 |
Exercise and nitrite prevent and Nω-nitrol-L-arginine methyl ester reproduces imbalance in the nuclear factor-κB/NADPH oxidase 2 and nuclear factor erythroid 2-related factor 2/NADPH oxidase 4/endothelial nitric oxide synthase systems in diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Hydrogen Peroxide; NADPH Oxidase 2; NADPH Oxidase 4; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Nitroglycerin; Oxidative Stress; Rats | 2021 |
Serine-arginine-rich protein kinase-1 inhibition for the treatment of diabetic retinopathy.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Humans; Hyperglycemia; Macular Edema; Ophthalmic Solutions; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Serine; Serine-Arginine Splicing Factors; Vascular Endothelial Growth Factor A | 2022 |
Cysteine-Rich Whey Protein Isolate (CR-WPI) Ameliorates Erectile Dysfunction by Diminishing Oxidative Stress via DDAH/ADMA/NOS Pathway.
Topics: Amidohydrolases; Animals; Arginine; Cysteine; Diabetes Mellitus, Experimental; Erectile Dysfunction; Humans; Hydrogen Peroxide; Male; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Whey Proteins | 2022 |
Serum untargeted metabolomics analysis of the mechanisms of evodiamine on type 2 diabetes mellitus model rats.
Topics: Amino Sugars; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glutathione; Metabolomics; Nucleotides; Proline; Quinazolines; Rats; Streptozocin; Tryptophan | 2022 |
Effects of Chicken Serum Metabolite Treatment on the Blood Glucose Control and Inflammatory Response in Streptozotocin-Induced Type 2 Diabetes Mellitus Rats.
Topics: Animals; Arginine; Blood Glucose; Chickens; Chromatography, Liquid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glycemic Control; Hyperglycemia; Hypoglycemic Agents; Insulin; Rats; Streptozocin; Tandem Mass Spectrometry | 2022 |
Antioxidant, antiapoptotic, and antifibrotic abilities of L-Arginine ameliorate the testicular dysfunction in diabetic rats.
Topics: Animals; Antioxidants; Arginine; Caspase 3; Diabetes Mellitus, Experimental; Male; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Testis; Transforming Growth Factor beta1 | 2023 |
Injectable thermogel incorporating reactive oxygen species scavenger and nitric oxide donor to accelerate the healing process of diabetic wounds.
Topics: Animals; Anti-Bacterial Agents; Arginine; Diabetes Mellitus, Experimental; Fishes; Hydrogels; Mice; Nitric Oxide Donors; Reactive Oxygen Species; Resveratrol | 2023 |
Analysis of Mechanisms Underlying the Development of Endothelial Dysfunction and Functional Disorders in Experimental Diabetes Mellitus and Their Pathogenetic Correction.
Topics: Animals; Arginine; Carnitine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Sodium-Potassium-Exchanging ATPase | 2023 |
Asymmetric dimethylarginine aggravates blood-retinal barrier breakdown of diabetic retinopathy via inhibition of intercellular communication in retinal pericytes.
Topics: Animals; Apoptosis; Arginine; Blood-Retinal Barrier; Cell Communication; Cell Membrane Permeability; Cells, Cultured; Connexin 43; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gap Junctions; Glucose; Male; Pericytes; Rats; Rats, Sprague-Dawley; Streptozocin | 2019 |
ADMA elevation does not exacerbate development of diabetic nephropathy in mice with streptozotocin-induced diabetes mellitus.
Topics: Amidohydrolases; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glomerular Filtration Rate; Male; Mice; Mice, Inbred C57BL; Risk Factors; Streptozocin | 2019 |
Restoration of Adiponectin-Connexin43 Signaling Mitigates Myocardial Inflammation and Dysfunction in Diabetic Female Rats.
Topics: Adiponectin; Animals; Arginine; Connexin 43; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Estradiol; Estrogen Receptor alpha; Female; Heme Oxygenase (Decyclizing); Hypertrophy, Left Ventricular; Ovariectomy; Piperidines; Rats, Wistar; Receptors, Adiponectin; Receptors, G-Protein-Coupled; Signal Transduction; Tumor Necrosis Factor-alpha; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Enhancing kidney DDAH-1 expression by adenovirus delivery reduces ADMA and ameliorates diabetic nephropathy.
Topics: Adenoviridae; Albuminuria; Amidohydrolases; Animals; Arginine; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Genetic Therapy; Genetic Vectors; Inflammation Mediators; Kidney; Male; Mice, Inbred DBA; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Signal Transduction; Thiobarbituric Acid Reactive Substances | 2020 |
Homocysteine and Asymmetrical Dimethylarginine in Diabetic Rats Treated with Docosahexaenoic Acid-Loaded Zinc Oxide Nanoparticles.
Topics: Animals; Arginine; Cellulose; Diabetes Mellitus, Experimental; Docosahexaenoic Acids; Homocysteine; Hyperhomocysteinemia; Insulin; Insulin Resistance; Male; Metal Nanoparticles; Microscopy, Electron, Transmission; Nitric Oxide; Rats; Risk Factors; Zinc Oxide | 2020 |
Insulinotropic and antidiabetic effects of β-caryophyllene with l-arginine in type 2 diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Polycyclic Sesquiterpenes; Rats | 2020 |
Pathophysiological changes of the lower urinary tract behind voiding dysfunction in streptozotocin-induced long-term diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Male; Rats; Rats, Wistar; Residual Volume; Streptozocin; Tadalafil; Urinary Bladder | 2020 |
Characterization and therapeutic efficacy evaluation of glimepiride and L-arginine co-amorphous formulation prepared by supercritical antisolvent process: Influence of molar ratio and preparation methods.
Topics: Administration, Oral; Animals; Arginine; Blood Glucose; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Combinations; Drug Compounding; Drug Liberation; Humans; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Male; Particle Size; Powder Diffraction; Rats; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Streptozocin; Sulfonylurea Compounds; X-Ray Diffraction | 2020 |
A role for NPY-NPY2R signaling in albuminuric kidney disease.
Topics: Albuminuria; Animals; Arginine; Benzazepines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Down-Regulation; Doxorubicin; Humans; Insulin; Kidney Diseases; Kidney Glomerulus; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neuropeptide Y; Podocytes; Proteomics; Receptors, Neuropeptide Y; Signal Transduction | 2020 |
Modulation of Nitric Oxide Bioavailability Attenuates Ischemia-Reperfusion Injury in Type II Diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Reperfusion Injury; Skin; Surgical Flaps | 2021 |
Asymmetrical dimethylarginine induces dysfunction of insulin signal transduction via endoplasmic reticulum stress in the liver of diabetic rats.
Topics: Animals; Apoptosis; Arginine; Diabetes Mellitus, Experimental; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Glucose Intolerance; Hepatocytes; Insulin; Insulin Resistance; Liver; Male; Rats; Rats, Sprague-Dawley; Signal Transduction | 2020 |
Fluorophore-Promoted Facile Deprotonation and Exocyclic Five-Membered Ring Cyclization for Selective and Dynamic Tracking of Labile Glyoxals.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Cyclization; Diabetes Mellitus; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; Fluorescent Dyes; Formaldehyde; Glyoxal; HeLa Cells; Humans; Mass Spectrometry; Mice; Microscopy, Fluorescence | 2020 |
Neuropeptide Y and glutamatergic mechanisms in the amygdala and ventral hippocampus differentially mediate impaired social behavior in diabetic mice.
Topics: Animals; Arginine; Basolateral Nuclear Complex; Behavior, Animal; Benzazepines; Cognitive Dysfunction; Diabetes Complications; Diabetes Mellitus, Experimental; Excitatory Amino Acid Antagonists; Hippocampus; Male; Mice; Mice, Inbred ICR; Neuropeptide Y; Receptors, AMPA; Receptors, Neuropeptide Y; Social Behavior | 2021 |
Abnormalities of the PRMT1-ADMA-DDAH1 metabolism axis and probucol treatment in diabetic patients and diabetic rats.
Topics: Amidohydrolases; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Humans; Nitric Oxide; Probucol; Protein-Arginine N-Methyltransferases; Rats; Repressor Proteins | 2021 |
Endogenous asymmetric dimethylarginine accumulation precipitates the cardiac and mitochondrial dysfunctions in type 1 diabetic rats.
Topics: Acetylcysteine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Free Radical Scavengers; Glycosylation; Heart Diseases; Insulin Resistance; Male; Mitochondria; Myocardial Contraction; Myocytes, Cardiac; Nitric Oxide; Papillary Muscles; Rats, Sprague-Dawley; Signal Transduction; Streptozocin | 2021 |
Early energy metabolism-related molecular events in skeletal muscle of diabetic rats: The effects of l-arginine and SOD mimic.
Topics: AMP-Activated Protein Kinases; Animals; Arginine; Diabetes Mellitus, Experimental; Energy Metabolism; Glucose Transporter Type 4; GTP Phosphohydrolases; Manganese; Mitochondria; Muscle, Skeletal; Nitric Oxide; Organometallic Compounds; Oxidative Phosphorylation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Superoxides | 2017 |
Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.
Topics: Aging; Aldosterone; Amidohydrolases; Animals; Arginine; Cell Line; Creatinine; Diabetes Mellitus, Experimental; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Gene Knockout Techniques; Humans; Kidney Diseases; Kidney Tubules, Proximal; Mice | 2017 |
Argatroban Attenuates Diabetic Cardiomyopathy in Rats by Reducing Fibrosis, Inflammation, Apoptosis, and Protease-Activated Receptor Expression.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Fibrosis; Heart; Inflammation; Male; Myocardium; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Receptors, Proteinase-Activated; Signal Transduction; Sulfonamides | 2017 |
Pyrrolidine dithiocarbamate ameliorates endothelial dysfunction in thoracic aorta of diabetic rats by preserving vascular DDAH activity.
Topics: Amidohydrolases; Animals; Aorta, Thoracic; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; HEK293 Cells; Humans; Nitric Oxide; Oxidative Stress; Pyrrolidines; Rats; Thiocarbamates; Vasodilation | 2017 |
L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration.
Topics: Administration, Oral; Agmatine; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Neuralgia; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin | 2018 |
Inhibition of Y1 receptor signaling improves islet transplant outcome.
Topics: Animals; Arginine; Cyclic AMP; Diabetes Mellitus, Experimental; Humans; Insulin; Insulin Secretion; Insulin-Secreting Cells; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Receptors, Neuropeptide Y; Signal Transduction | 2017 |
Morphine hyposensitivity in streptozotocin-diabetic rats: Reversal by dietary l-arginine treatment.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diet; Hyperalgesia; Morphine; Nitric Oxide; Rats | 2018 |
Biocompatible zinc oxide nanocrystals stabilized via hydroxyethyl cellulose for mitigation of diabetic complications.
Topics: Animals; Arginine; Biocompatible Materials; Cardiovascular Diseases; Cellulose; Diabetes Mellitus, Experimental; Humans; Hyperglycemia; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Rats; Zinc Oxide | 2018 |
Obesity-induced vascular dysfunction and arterial stiffening requires endothelial cell arginase 1.
Topics: Animals; Arginase; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Dietary Sucrose; Endothelium, Vascular; Enzyme Inhibitors; Fibrosis; Genetic Predisposition to Disease; Insulin; Male; Metabolic Syndrome; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Obesity; Ornithine; Oxidative Stress; Phenotype; Signal Transduction; Vascular Diseases; Vascular Stiffness; Vasodilation | 2017 |
ADMA reduction does not protect mice with streptozotocin-induced diabetes mellitus from development of diabetic nephropathy.
Topics: Albuminuria; Amidohydrolases; Animals; Arginine; Cell Proliferation; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Down-Regulation; Genetic Predisposition to Disease; Glomerular Mesangium; Glomerulonephritis; Hydrolysis; Kidney; Male; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Streptozocin | 2017 |
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O
Topics: Animals; Anthraquinones; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Combinations; Endothelium, Vascular; Insulin Resistance; Male; NADPH Oxidase 4; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2018 |
Asymmetric dimethylarginine contributes to retinal neovascularization of diabetic retinopathy through EphrinB2 pathway.
Topics: Amidohydrolases; Animals; Arginine; Cell Hypoxia; Cell Line; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; Ephrin-B2; Human Umbilical Vein Endothelial Cells; Humans; Macaca mulatta; Male; Protein-Arginine N-Methyltransferases; Rats, Sprague-Dawley; Retinal Neovascularization; Retinal Vessels; RNA Interference; Signal Transduction | 2018 |
Probucol improves erectile function via Activation of Nrf2 and coordinates the HO-1 / DDAH / PPAR-γ/ eNOS pathways in streptozotocin-induced diabetic rats.
Topics: Amidohydrolases; Animals; Arginine; Blood Glucose; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Erectile Dysfunction; Heme Oxygenase-1; Male; Malondialdehyde; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; PPAR gamma; Probucol; Rats, Sprague-Dawley; Signal Transduction; Streptozocin; Superoxide Dismutase | 2018 |
Protective effects of either C-peptide or l-arginine on pancreatic β-cell function, proliferation, and oxidative stress in streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Blood Glucose; C-Peptide; Cell Proliferation; Diabetes Mellitus, Experimental; Gene Expression Regulation; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Male; Oxidative Stress; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley | 2019 |
Synthesis of docosahexaenoic acid-loaded silver nanoparticles for improving endothelial dysfunctions in experimental diabetes.
Topics: Animals; Arginine; Aryldialkylphosphatase; Blood Glucose; Diabetes Mellitus, Experimental; DNA Damage; Docosahexaenoic Acids; Insulin; Male; Membrane Lipids; Metal Nanoparticles; Nitric Oxide; Rats, Wistar; Silver | 2019 |
Anti-Diabetic Effects of Gynura Bicolor Aqueous Extract in Mice.
Topics: Animals; Antidiuretic Agents; Arginine; Asteraceae; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Humans; Kidney; Liver; Lysine; Male; Mice; Mice, Inbred BALB C; NF-kappa B; Plant Extracts; Reactive Oxygen Species | 2019 |
Depressed calcium-handling proteins due to endoplasmic reticulum stress and apoptosis in the diabetic heart are attenuated by argirein.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Apoptosis; Arginine; Calcium-Binding Proteins; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Dose-Response Relationship, Drug; Down-Regulation; Drug Combinations; Endoplasmic Reticulum Stress; Guanidines; Male; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Streptozocin; Tacrolimus Binding Proteins; Up-Regulation | 2013 |
Blockage of peripheral NPY Y1 and Y2 receptors modulates barorefex sensitivity of diabetic rats.
Topics: Animals; Arginine; Baroreflex; Benzazepines; Blood Pressure; Cholesterol; Cholesterol, LDL; Diabetes Mellitus, Experimental; Heart Rate; Hyperlipidemias; Male; Neuropeptide Y; Nitroprusside; Phenylephrine; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Triglycerides | 2013 |
Aegle marmelos Correa leaf extract prevents secondary complications in streptozotocin-induced diabetic rats and demonstration of limonene as a potent antiglycating agent.
Topics: Aegle; Animals; Antioxidants; Arginine; Body Weight; Cataract; Collagen; Cyclohexenes; Diabetes Mellitus, Experimental; Eating; Glycation End Products, Advanced; Hypoglycemic Agents; Kidney; Limonene; Lysine; Male; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Terpenes | 2013 |
Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Apoptosis; Arginine; Diabetes Mellitus, Experimental; Diet, High-Fat; Drug Combinations; eIF-2 Kinase; Endoplasmic Reticulum Stress; Glucose; Glucose Transporter Type 4; Glutathione Peroxidase; Glycogen; Heat-Shock Proteins; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Tetrazoles; Transcription Factor CHOP; Valine; Valsartan | 2013 |
Male hypogonadism induced by high fat diet and low dose streptozotocin is mediated by activated endoplasmic reticulum stress and IκBβ and attenuated by argirein and valsartan.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; Drug Combinations; Endoplasmic Reticulum Stress; Hypogonadism; I-kappa B Proteins; Male; Rats; Rats, Sprague-Dawley; Sexual Behavior, Animal; Streptozocin; Tetrazoles; Valine; Valsartan | 2013 |
Poly(ester amide) blend microspheres for oral insulin delivery.
Topics: Administration, Oral; Animals; Arginine; Biological Availability; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Leucine; Lysine; Male; Microspheres; Nylons; Polyesters; Rats; Rats, Wistar | 2013 |
Inhibition of peripheral NPY Y1 and Y2 receptors ameliorates the aberrant baroreceptor reflex sensitivity in streptozotocin induced diabetic rats.
Topics: Animals; Arginine; Baroreflex; Benzazepines; Blood Pressure; Bradycardia; Diabetes Mellitus, Experimental; Heart Rate; Myocardial Contraction; Neuropeptide Y; Rats; Receptors, Neuropeptide Y; Streptozocin | 2013 |
Mitochondrial dysfunction in brain cortex mitochondria of STZ-diabetic rats: effect of l-Arginine.
Topics: Animals; Arginine; Blood Glucose; Blotting, Western; Body Weight; Cerebral Cortex; Diabetes Mellitus, Experimental; Lipid Peroxidation; Male; Mitochondria; Nitric Oxide; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin | 2013 |
Administration of heme arginate ameliorates murine type 2 diabetes independently of heme oxygenase activity.
Topics: 3T3 Cells; Adipocytes; Adipogenesis; Adiponectin; Adipose Tissue; Adiposity; Animals; Arginine; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Heme; Heme Oxygenase (Decyclizing); Hyperglycemia; Inflammation; Insulin-Secreting Cells; Metalloporphyrins; Mice; Pilot Projects | 2013 |
Effects of endogenous regulators of endothelial NO synthase on nitric oxide homeostasis and blood serum lipoproteins during experimental diabetes mellitus.
Topics: Animals; Arginine; Cholesterol; Diabetes Mellitus, Experimental; Endothelial Cells; Glycated Hemoglobin; Lipoproteins, HDL; Lipoproteins, LDL; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Ubiquinone | 2013 |
Assessment of androgen replacement therapy for erectile function in rats with type 2 diabetes mellitus by examining nitric oxide-related and inflammatory factors.
Topics: Androgens; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Electric Stimulation; Erectile Dysfunction; Hormone Replacement Therapy; Interleukin-6; Male; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Penile Erection; Penis; Rats, Long-Evans; Testosterone; Tumor Necrosis Factor-alpha | 2014 |
Prevention of arterial stiffening by using low-dose atorvastatin in diabetes is associated with decreased malondialdehyde.
Topics: Animals; Arginine; Atorvastatin; Blood Glucose; Blood Pressure; Body Weight; C-Reactive Protein; Cholesterol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fatty Acids; Glycation End Products, Advanced; Hemodynamics; Heptanoic Acids; Lysine; Male; Malondialdehyde; Organ Size; Pyrroles; Rats, Wistar; Streptozocin; Vascular Stiffness | 2014 |
L-Citrulline, but not L-arginine, prevents diabetes mellitus-induced glomerular hyperfiltration and proteinuria in rat.
Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Oxygen Consumption; Proteinuria; Rats | 2014 |
Effects of oleuropein in rats with simultaneous type 2 diabetes and renal hypertension: a study of antihypertensive mechanisms.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Endothelium, Vascular; Hypertension, Renal; Iridoid Glucosides; Iridoids; Male; Molecular Structure; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2014 |
Endothelial arginine resynthesis contributes to the maintenance of vasomotor function in male diabetic mice.
Topics: Acetylcholine; Animals; Arginase; Arginine; Argininosuccinate Synthase; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Endothelial Cells; Endothelium; Female; Heart Rate; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroprusside; Phenylephrine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vasomotor System | 2014 |
Renal response to L-arginine in diabetic rats. A possible link between nitric oxide system and aquaporin-2.
Topics: Animals; Aquaporin 2; Arginine; Blood Glucose; Citrulline; Diabetes Mellitus, Experimental; Kidney Medulla; Kidney Tubules, Collecting; Male; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Streptozocin | 2014 |
Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation.
Topics: Amino Acids; Animals; Arginase; Arginine; Blood Pressure; Citrulline; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Fibronectins; Kidney; Male; Membrane Proteins; Mice; Mice, Inbred DBA; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Tumor Necrosis Factor-alpha | 2014 |
Modulatory effects of l-arginine and soy enriched diet on bone homeostasis abnormalities in streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Bone and Bones; Diabetes Complications; Diabetes Mellitus, Experimental; Diet; Dietary Supplements; Homeostasis; Male; Osteocalcin; Osteogenesis; Osteoporosis; Parathyroid Hormone; Rats; Rats, Wistar; Soy Foods | 2015 |
Role of GABAB receptor and L-Arg in GABA-induced vasorelaxation in non-diabetic and streptozotocin-induced diabetic rat vessels.
Topics: Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hypertension; Male; Mesenteric Artery, Superior; Nitric Oxide; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Streptozocin; Vasodilation | 2015 |
The Effect of Agaricus brasiliensis and Ganoderma lucidum Medicinal Mushroom Administration on the L-arginine/Nitric Oxide System and Rat Leukocyte Apoptosis in Experimental Type 1 Diabetes Mellitus.
Topics: Agaricus; Animals; Apoptosis; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diet; Leukocytes; Male; Nitric Oxide; Rats; Reishi | 2015 |
Vascular smooth muscle LRP6 limits arteriosclerotic calcification in diabetic LDLR-/- mice by restraining noncanonical Wnt signals.
Topics: Animals; Arginine; Arteriosclerosis; Calcinosis; Diabetes Mellitus, Experimental; Dietary Fats; Frizzled Receptors; Gene Expression Regulation; Histones; Low Density Lipoprotein Receptor-Related Protein-6; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Osteopontin; Paracrine Communication; Protein Interaction Mapping; Protein-Arginine N-Methyltransferases; Receptors, Cell Surface; Receptors, LDL; Upstream Stimulatory Factors; Vascular Stiffness; Wnt Signaling Pathway | 2015 |
Mature coconut water exhibits antidiabetic and antithrombotic potential via L-arginine-nitric oxide pathway in alloxan induced diabetic rats.
Topics: Alloxan; Animals; Arginine; Blood Coagulation; Blood Glucose; Cocos; Diabetes Mellitus, Experimental; Fibrinolytic Agents; Hypoglycemic Agents; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2015 |
Houttuynia cordata aqueous extract attenuated glycative and oxidative stress in heart and kidney of diabetic mice.
Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Creatine Kinase; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fructose; Glutathione; Heart; Houttuynia; Insulin; Interleukin-6; Kidney; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Oxidative Stress; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Tumor Necrosis Factor-alpha | 2016 |
Lupanine Improves Glucose Homeostasis by Influencing KATP Channels and Insulin Gene Expression.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression Regulation; Homeostasis; Insulin; Insulin Secretion; Insulin-Secreting Cells; KATP Channels; Mice; Mice, Inbred C57BL; Rats; Sparteine; Streptozocin | 2015 |
Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model.
Topics: Animals; Arginase; Arginine; Bone and Bones; Bone Density; Cells, Cultured; Diabetes Mellitus, Experimental; Diet, High-Fat; Glucose; Mesenchymal Stem Cells; Mice; Nitric Oxide; Streptozocin; Sucrose; Up-Regulation | 2016 |
Argirein alleviates stress-induced and diabetic hypogonadism in rats via normalizing testis endothelin receptor A and connexin 43.
Topics: Animals; Anthraquinones; Arginine; Connexin 43; Diabetes Mellitus, Experimental; Drug Combinations; Drugs, Chinese Herbal; Hypogonadism; Isoproterenol; Male; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Rheum; Streptozocin; Testis; Testosterone | 2016 |
Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Female; Hyperalgesia; Ibuprofen; MicroRNAs; Muscles; Nitric Oxide; Peripheral Nervous System Diseases; Rats, Wistar; Skin; Spinal Cord; Streptozocin; Up-Regulation | 2016 |
Targeting the superoxide/nitric oxide ratio by L-arginine and SOD mimic in diabetic rat skin.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Male; Nitric Oxide; Oxidation-Reduction; Rats; Superoxides | 2016 |
L-Arginine supplementation improves insulin sensitivity and beta cell function in the offspring of diabetic rats through AKT and PDX-1 activation.
Topics: Adipose Tissue; Animals; Arginine; Diabetes Mellitus, Experimental; Enzyme Activation; Female; Gene Expression Regulation; Homeodomain Proteins; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Membrane Glycoproteins; Mothers; Muscle, Skeletal; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Trans-Activators | 2016 |
Oral or topical administration of L-arginine changes the expression of TGF and iNOS and results in early wounds healing.
Topics: Administration, Oral; Administration, Topical; Animals; Arginine; Collagen; Cytokines; Diabetes Mellitus, Experimental; Disease Models, Animal; Immunocompromised Host; Inflammation; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Surgical Wound; Transforming Growth Factor beta; Wound Healing; Wounds and Injuries | 2016 |
Cellular transport of l-arginine determines renal medullary blood flow in control rats, but not in diabetic rats despite enhanced cellular uptake capacity.
Topics: Animals; Arginine; Biological Transport; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Homoarginine; Kidney Medulla; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Renal Circulation | 2017 |
Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arginase; Arginine; Cytoprotection; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; omega-N-Methylarginine; Protein Kinase Inhibitors; Rats, Sprague-Dawley; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction | 2017 |
Fish oil prevents rodent anxious states comorbid with diabetes: A putative involvement of nitric oxide modulation.
Topics: Amygdala; Animals; Anxiety; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Inhibitors; Fish Oils; Hippocampus; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Periaqueductal Gray; Rats; Rats, Wistar; Streptozocin | 2017 |
L-Arginine prevents metabolic effects of high glucose in diabetic mice.
Topics: Aldehyde Reductase; Animals; Aortitis; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glutathione; Heart Diseases; Hyperglycemia; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Phosphorylation; Polymers; Protein Kinase C; Protein Kinase C beta; Sorbitol; Superoxides | 2008 |
Antiglycative and anti-VEGF effects of s-ethyl cysteine and s-propyl cysteine in kidney of diabetic mice.
Topics: Albuminuria; Animals; Arginine; Blood Glucose; Creatinine; Cysteine; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Kidney; Lysine; Male; Mice; Mice, Inbred BALB C; Organ Size; Vascular Endothelial Growth Factor A | 2008 |
[Searching for ways to correct thymic dysfunction in rats with experimental diabetes mellitus].
Topics: Animals; Apoptosis; Arginine; Cell Proliferation; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Insulin; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitroarginine; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; T-Lymphocytes; Thymus Gland | 2008 |
Effects of nitrosative stress and reactive oxygen-scavenging systems in esophageal physiopathy under streptozotocin-induced experimental hyperglycemia.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Esophagus; Glutathione Peroxidase; Glycosylation; Hyperglycemia; Indomethacin; Lipid Peroxidation; Male; Malondialdehyde; Mucous Membrane; Nitric Oxide; Nitrosation; Oxidative Stress; Rats; Rats, Wistar; Reactive Oxygen Species; Streptozocin | 2008 |
Gastrointestinal dysfunction in diabetic rats relates with a decline in tissue L-arginine content and consequent low levels of nitric oxide.
Topics: Analysis of Variance; Animals; Arginine; Barium Sulfate; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Gastric Emptying; Gastrointestinal Transit; Ileum; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pylorus; Rats; Rats, Sprague-Dawley | 2009 |
Polyamines protect rat embryo in vitro from high glucose-induced developmental delay and dysmorphogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Arginine; Diabetes Mellitus, Experimental; Drug Combinations; Embryo, Mammalian; Embryonic Development; Female; Glucose; Organ Culture Techniques; Rats; Rats, Wistar; Spermine | 2009 |
Insulin signaling in alpha cells modulates glucagon secretion in vivo.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Fasting; Feeding Behavior; Gene Expression Regulation; Glucagon; Glucagon-Secreting Cells; Glucose Intolerance; Hyperinsulinism; Hypoglycemia; Insulin; Insulin-Secreting Cells; Mice; Mice, Knockout; Organ Size; Organ Specificity; Receptor, Insulin; Signal Transduction; Streptozocin | 2009 |
L-arginine supplementation normalizes bone turnover and preserves bone mass in streptozotocin-induced diabetic rats.
Topics: Alkaline Phosphatase; Animals; Arginine; Bone Density; Bone Diseases, Metabolic; Bone Remodeling; Calcium; Collagen Type I; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Male; Nitric Oxide Donors; Osteocalcin; Peptides; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric | 2009 |
PRMT-1 and DDAHs-induced ADMA upregulation is involved in ROS- and RAS-mediated diabetic retinopathy.
Topics: Amidohydrolases; Animals; Arginine; Blotting, Western; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; Male; Protein-Arginine N-Methyltransferases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin-Angiotensin System; Up-Regulation | 2009 |
Ex vivo gene transferring of human dimethylarginine dimethylaminohydrolase-2 improved endothelial dysfunction in diabetic rat aortas and high glucose-treated endothelial cells.
Topics: Amidohydrolases; Animals; Aorta; Arginine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Endothelium, Vascular; Gene Transfer Techniques; Glucose; Humans; Hyperglycemia; Male; Rats; Rats, Sprague-Dawley | 2010 |
Critical evaluation of toxic versus beneficial effects of methylglyoxal.
Topics: Animals; Arginine; Cataract; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Delivery Systems; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Lysine; Maillard Reaction; Oxidative Stress; Protein Conformation; Protein Folding; Pyruvaldehyde; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serum Albumin | 2009 |
Therapeutic angiogenesis in diabetic apolipoprotein E-deficient mice using bone marrow cells, functional hemangioblasts and metabolic intervention.
Topics: Animals; Apolipoproteins E; Arginine; Ascorbic Acid; Bone Marrow Transplantation; Diabetes Mellitus, Experimental; Hemangioblasts; Hindlimb; Ischemia; Mice; Neovascularization, Physiologic; Peripheral Vascular Diseases; Regional Blood Flow; Vitamin E | 2010 |
L-arginine and antioxidant diet supplementation partially restores nitric oxide-dependent regulation of phenylephrine renal vasoconstriction in diabetics rats.
Topics: Animals; Antioxidants; Arginine; Ascorbic Acid; Biopterins; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenylephrine; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Vasoconstriction; Vasoconstrictor Agents; Vitamin E | 2010 |
Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase.
Topics: Animals; Aorta, Thoracic; Arginine; Cattle; Cells, Cultured; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelial Cells; Glycation End Products, Advanced; Hypoglycemic Agents; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Vascular Diseases; Vasodilation; Vasodilator Agents | 2010 |
Effects of dietary arginine on inflammatory mediator and receptor of advanced glycation endproducts (RAGE) expression in rats with streptozotocin-induced type 2 diabetes.
Topics: Animals; Arginine; Blood Glucose; C-Reactive Protein; Diabetes Mellitus, Experimental; Dietary Supplements; Fructosamine; Inflammation Mediators; Liver; Lung; Male; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic | 2010 |
Expression pattern of thermogenesis-related factors in interscapular brown adipose tissue of alloxan-treated rats: beneficial effect of L-arginine.
Topics: Adipose Tissue, Brown; Alloxan; Analysis of Variance; Animals; Antioxidants; Arginine; Back; Body Weight; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Ion Channels; Male; Mitochondrial Proteins; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR gamma; Rats; Regional Blood Flow; RNA-Binding Proteins; Thermogenesis; Transcription Factors; Uncoupling Protein 1 | 2010 |
The redox enzyme p66Shc contributes to diabetes and ischemia-induced delay in cutaneous wound healing.
Topics: Animals; Arginine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Lysine; Mice; Mice, Knockout; Muscle, Skeletal; Oxidation-Reduction; Shc Signaling Adaptor Proteins; Skin; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine; Wound Healing | 2010 |
An in vivo experimental study on osteopenia in diabetic rats.
Topics: Animals; Apoptosis; Arginine; Bone Diseases, Metabolic; Diabetes Mellitus, Experimental; Immunohistochemistry; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Osteogenesis; Rats; Rats, Sprague-Dawley; Streptozocin | 2011 |
Simultaneous determination of guanidinosuccinic acid and guanidinoacetic acid in urine using high performance liquid chromatography/tandem mass spectrometry.
Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Creatinine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Glycine; Guanidines; Homoarginine; Male; Mice; Mice, Inbred C57BL; Succinates; Tandem Mass Spectrometry | 2010 |
Does detraining restore influence of exercise training on microvascular responses in streptozotocin-induced diabetic rats?
Topics: Administration, Cutaneous; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enzyme Inhibitors; Iontophoresis; Laser-Doppler Flowmetry; Male; Microcirculation; Microinjections; Microvessels; Nitric Oxide; Nitric Oxide Synthase; Physical Exertion; Rats; Rats, Wistar; Skin; Time Factors; Vasodilation; Vasodilator Agents | 2010 |
Gender differences in vascular reactivity of aortas from streptozotocin-induced diabetic mice.
Topics: Acetylcholine; Adiponectin; Animals; Aorta; Arginine; Clonidine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Insulin; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitroprusside; Norepinephrine; Sex Factors; Vasoconstriction; Vasodilation | 2010 |
[Effect of L-arginine and aminoguanidine on morphological characteristics of the lymphocyte plasma membranes during experimental diabetes mellitus].
Topics: Animals; Arginine; Cell Culture Techniques; Cell Membrane; Cell Size; Cells, Cultured; Diabetes Mellitus, Experimental; Guanidines; Lymphocytes; Male; Rats; Rats, Wistar | 2010 |
Involvement of vascular endothelial nitric oxide synthase in development of experimental diabetic nephropathy in rats.
Topics: Animals; Arginine; Blood Glucose; Blood Urea Nitrogen; Body Weight; Caveolin 1; Cholesterol; Collagen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dietary Fats; Endothelium, Vascular; Isoflavones; Kidney; Male; Nitric Oxide Synthase Type III; Nitrites; Organ Size; Proteinuria; Rats; Rats, Wistar; Sodium Nitrite; Urine | 2011 |
[The changes of oxidative-reductive processes and fatty acid composition of liver lipids in rats with streptozotocin-induced diabetes].
Topics: Animals; Antioxidants; Arginine; Diabetes Mellitus, Experimental; Fatty Acids; Lipid Peroxidation; Lipid Peroxides; Liver; Male; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Rats; Streptozocin | 2010 |
Contribution of endogenous inhibitor of nitric oxide synthase to hepatic mitochondrial dysfunction in streptozotocin-induced diabetic rats.
Topics: Adenosine Triphosphate; Animals; Arginine; Cell Line, Tumor; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Hepatocytes; Ion Channels; Liver; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Proteins; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Superoxide Dismutase; Transcription Factors; Uncoupling Protein 2 | 2011 |
Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues.
Topics: Amino Acid Motifs; Animals; Arginine; Collagen Type IV; Diabetes Mellitus, Experimental; Glucose; Glyoxal; Hyperglycemia; Male; Micrococcus; Muramidase; Protein Carbonylation; Protein Structure, Tertiary; Proteins; Pyruvaldehyde; Random Allocation; Rats; Rats, Sprague-Dawley | 2011 |
Metabolic function of a suboptimal transplanted islet mass in nonhuman primates on rapamycin monotherapy.
Topics: Animals; Arginine; Blood Glucose; C-Peptide; Diabetes Mellitus, Experimental; Glucagon; Glucose Tolerance Test; Immunosuppressive Agents; Insulin; Insulin-Secreting Cells; Islets of Langerhans Transplantation; Macaca fascicularis; Sirolimus | 2012 |
Arginine-rich coconut kernel diet influences nitric oxide synthase activity in alloxandiabetic rats.
Topics: Animals; Antioxidants; Arginase; Arginine; Blood Glucose; Cocos; Diabetes Mellitus, Experimental; Diet; Dietary Proteins; Glycogen; Insulin; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pancreas; Phytotherapy; Plant Preparations; Plant Proteins; Rats; Rats, Sprague-Dawley; Seeds; Signal Transduction | 2012 |
Renal protective effects of extracts from guava fruit (Psidium guajava L.) in diabetic mice.
Topics: Aldehyde Reductase; Animals; Anti-Inflammatory Agents; Antioxidants; Arginine; Blood Glucose; Blood Urea Nitrogen; Cytokines; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Fructose; Fruit; Hypoglycemic Agents; Insulin; Kidney; Lysine; Male; Mice; Mice, Inbred BALB C; Phytotherapy; Plant Extracts; Psidium; Reactive Oxygen Species | 2012 |
Effects of a diabetes-specific enteral nutrition on nutritional and immune status of diabetic, obese, and endotoxemic rats: interest of a graded arginine supply.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Endotoxemia; Enteral Nutrition; Food, Formulated; Insulin; Macrophages; Male; Nitric Oxide; Nutritional Status; Obesity; Rats; Rats, Zucker; Tumor Necrosis Factor-alpha | 2012 |
Effect of vitamin D on aortic remodeling in streptozotocin-induced diabetes.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Arginine; Biomarkers; Blood Pressure; Cholecalciferol; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dietary Supplements; Elastic Tissue; Elasticity; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Male; Pulsatile Flow; Radioimmunoassay; Rats; Rats, Wistar; Streptozocin; Time Factors; Vasoconstrictor Agents; Vasodilator Agents; Vitamin D | 2012 |
Inflammatory milieu as an early marker of kidney injury in offspring rats from diabetic mothers.
Topics: Acute Kidney Injury; Animals; Arginine; Biomarkers; Diabetes Mellitus, Experimental; Early Diagnosis; Female; Inflammation Mediators; Male; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Random Allocation; Rats; Rats, Wistar | 2012 |
Improvement of endothelial nitric oxide synthase activity retards the progression of diabetic nephropathy in db/db mice.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Endothelium, Vascular; Glucose; Kidney Glomerulus; Mice; Nitric Oxide Synthase Type III; Pterins | 2012 |
L-Arginine ameliorates cardiac left ventricular oxidative stress by upregulating eNOS and Nrf2 target genes in alloxan-induced hyperglycemic rats.
Topics: Alloxan; Animals; Arginine; Caspase 3; Diabetes Mellitus, Experimental; Gene Expression Regulation; Heart Ventricles; Hyperglycemia; Lipid Peroxidation; NF-E2-Related Factor 2; NF-kappa B; NG-Nitroarginine Methyl Ester; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Up-Regulation | 2012 |
Arginine-containing tripeptide Pro-Arg-Gly is involved in the regulation of the function of anticoagulation and insular systems under persistent hyperglycemia.
Topics: Administration, Intranasal; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptides; Factor XII; Fibrinolysis; Fibrinolytic Agents; Glucose; Male; Oligopeptides; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Rats; Tissue Plasminogen Activator | 2012 |
Coconut kernel-derived proteins enhance hypolipidemic and antioxidant activity in alloxan-induced diabetic rats.
Topics: Animals; Antioxidants; Arginine; Cocos; Diabetes Mellitus, Experimental; Dietary Proteins; Hypolipidemic Agents; Lipids; Male; Oxidative Stress; Peroxides; Plant Proteins; Rats; Rats, Sprague-Dawley; Seeds | 2013 |
Glucagon-like peptide-1 receptor agonist inhibits asymmetric dimethylarginine generation in the kidney of streptozotocin-induced diabetic rats by blocking advanced glycation end product-induced protein arginine methyltranferase-1 expression.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Drug Evaluation, Preclinical; Exenatide; Gene Expression Regulation, Enzymologic; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glycation End Products, Advanced; Humans; Hypertrophy; Hypoglycemic Agents; Kidney; Kidney Glomerulus; Kidney Tubules; Macrophages; Male; Peptides; Protein-Arginine N-Methyltransferases; Rats; Rats, Wistar; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Receptors, Glucagon; Receptors, Immunologic; Repressor Proteins; RNA, Messenger; Venoms | 2013 |
Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes.
Topics: Aldehydes; Animals; Arginine; Calcium; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Echocardiography; Guanidines; Lysine; Male; Malondialdehyde; Myocytes, Cardiac; Norleucine; Protein Carbonylation; Pyridoxamine; Pyrroles; Rats; Rats, Sprague-Dawley; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spin Labels | 2013 |
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.
Topics: Amidohydrolases; Animals; Antioxidants; Aorta; Arginine; Cell Line; Cells, Cultured; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Humans; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Oxidative Stress; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2002 |
Effects of chronic administration of L-arginine on vasoactive responses induced by endothelin-1 and its plasma level in streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelin-1; Male; Mesenteric Arteries; Methoxamine; Osmolar Concentration; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents | 2002 |
Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation.
Topics: Animals; Arginine; Arterioles; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Indoles; Male; Maleimides; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxidative Stress; Protein Kinase C; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spin Labels; Superoxides; Thioctic Acid; Vasodilation | 2003 |
Protein kinase Cbeta selective inhibitor LY333531 attenuates diabetic hyperalgesia through ameliorating cGMP level of dorsal root ganglion neurons.
Topics: Animals; Arginine; Cyclic GMP; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Enzyme Inhibitors; Ganglia, Spinal; Immunohistochemistry; Indoles; Male; Maleimides; NAV1.9 Voltage-Gated Sodium Channel; Neuropeptides; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nociceptors; Protein Kinase C; Protein Kinase C beta; Rats; Rats, Sprague-Dawley; Sodium Channels; Tetrodotoxin | 2003 |
Subcutaneous transplantation of macroencapsulated porcine pancreatic endocrine cells normalizes hyperglycemia in diabetic mice.
Topics: Animals; Anti-Infective Agents; Arginine; Capsules; Diabetes Mellitus, Experimental; Gels; Glucose; Graft Survival; Hyperglycemia; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Polystyrenes; Sepharose; Subcutaneous Tissue; Swine; Theophylline; Transplantation, Heterologous; Vasodilator Agents | 2003 |
Elevated levels of the serum endogenous inhibitor of nitric oxide synthase and metabolic control in rats with streptozotocin-induced diabetes.
Topics: Animals; Arginine; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Insulin; Male; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2003 |
NADPH diaphorase activity in the rat retina during the early stages of experimental diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diet; Electroretinography; Enzyme Inhibitors; Histocytochemistry; Male; NADPH Dehydrogenase; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Retina; Streptozocin | 2003 |
Reduction in [D-Ala2, NMePhe4, Gly-ol5]enkephalin-induced peripheral antinociception in diabetic rats: the role of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway.
Topics: Analgesics, Opioid; Animals; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Formaldehyde; Guanylate Cyclase; Male; Methylene Blue; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Pain; Pain Measurement; Rats; Rats, Wistar | 2004 |
Differential target molecules for toxicity induced by streptozotocin and alloxan in pancreatic islets of mice in vitro.
Topics: Alloxan; Animals; Arginine; Blotting, Western; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucokinase; Glucose; Glucose Transporter Type 2; Insulin; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; Monosaccharide Transport Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Streptozocin | 2004 |
Dietary L-arginine supplementation enhances endothelial nitric oxide synthesis in streptozotocin-induced diabetic rats.
Topics: Alanine; Amino Acids; Animals; Arginine; Blood Glucose; Body Weight; Coronary Vessels; Diabetes Mellitus, Experimental; Diet; Dietary Supplements; Endothelium, Vascular; Insulin; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reference Values | 2004 |
Augmented arginine uptake, through modulation of cationic amino acid transporter-1, increases GFR in diabetic rats.
Topics: Animals; Arginase; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glomerular Filtration Rate; Humans; In Vitro Techniques; Isoenzymes; Kidney Glomerulus; Male; Rats; Rats, Wistar; RNA, Messenger; Time Factors | 2004 |
Alteration of beta-cell constitutive NO synthase activity is involved in the abnormal insulin response to arginine in a new rat model of type 2 diabetes.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoenzymes; Male; Nitric Oxide Synthase; Rats; Rats, Wistar | 2004 |
Effects of dietary L-arginine supplementation on serum lipids and intestinal enzyme activities in diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dietary Supplements; Intestines; Male; Rats; Rats, Sprague-Dawley; Triglycerides | 2004 |
[The influence of L-arginine on the angiogenesis in burn wounds in diabetic rats].
Topics: Animals; Arginine; Blood Glucose; Burns; Diabetes Mellitus, Experimental; Male; Neovascularization, Physiologic; Nitric Oxide; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A; Wound Healing | 2004 |
Activated protein C preserves functional islet mass after intraportal transplantation: a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Enzyme Activation; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Protein C; Recombinant Proteins; Transplantation, Isogeneic | 2004 |
Effect of supplemental L-arginine on the function of T lymphocytes and the formation of advanced glycosylated end products in rats with streptozotocin-induced diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Immunologic; Fructosamine; Glycation End Products, Advanced; Glycine; Glycosylation; Lymphocyte Activation; Male; Rats; Rats, Wistar; T-Lymphocytes | 2005 |
Effect of diabetic duration on serum concentrations of endogenous inhibitor of nitric oxide synthase in patients and rats with diabetes.
Topics: Adult; Aged; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Streptozocin; Time Factors; Vasoconstriction | 2005 |
[Effect of L-arginine on the endothelium functional activity in experimental diabetes mellitus].
Topics: Animals; Aorta, Thoracic; Arginase; Arginine; Diabetes Mellitus, Experimental; Drug Synergism; Endothelium, Vascular; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Rats; Rats, Wistar; Vasoconstriction | 2005 |
L-arginine and polyamine administration protect beta-cells against alloxan diabetogenic effect in Sprague-Dawley rats.
Topics: Alloxan; Animals; Arginine; Blood Glucose; Body Weight; Bromodeoxyuridine; Cell Proliferation; Cholesterol; Diabetes Mellitus, Experimental; Drug Administration Schedule; Immunochemistry; Injections, Intraperitoneal; Insulin-Secreting Cells; Male; Polyamines; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides | 2005 |
[Effects of arginine on cutaneous underlying disorder in diabetic rats ].
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glucose; Male; Rats; Rats, Sprague-Dawley; Skin; Skin Diseases | 2005 |
Characterization of the action of S 21403 (mitiglinide) on insulin secretion and biosynthesis in normal and diabetic beta-cells.
Topics: Animals; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Gerbillinae; Glucose; Hypoglycemic Agents; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Isoindoles; Perfusion; Rats; Rats, Wistar | 2005 |
Modulatory role of green tea extract on antinociceptive effect of morphine in diabetic mice.
Topics: Analgesics; Animals; Arginine; Blood Glucose; Body Weight; Camellia sinensis; Diabetes Mellitus, Experimental; Drug Interactions; Enzyme Inhibitors; Male; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitrites; Pain Threshold; Plant Extracts; Streptozocin | 2005 |
Reduced nitric oxide concentration in the renal cortex of streptozotocin-induced diabetic rats: effects on renal oxygenation and microcirculation.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Kidney Cortex; Male; Microcirculation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Oxygen; Rats; Rats, Inbred WF; Renal Circulation | 2005 |
Measurements of insulin responses as predictive markers of pancreatic beta-cell mass in normal and beta-cell-reduced lean and obese Göttingen minipigs in vivo.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Niacinamide; Obesity; Predictive Value of Tests; Retrospective Studies; Streptozocin; Swine; Swine, Miniature | 2006 |
Inhibition by L-arginine and spermidine of hemoglobin glycation and lipid peroxidation in rats with induced diabetes.
Topics: Animals; Arginine; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Glycated Hemoglobin; Lipid Peroxidation; Lipoproteins; Male; Rats; Rats, Sprague-Dawley; Spermidine; Thiobarbituric Acid Reactive Substances; Triglycerides | 2006 |
Effect of gap junction uncoupler heptanol on resistance arteries reactivity in experimental models of diabetes, hyperlipemia and hyperlipemia-diabetes.
Topics: Acetylcholine; Animals; Arginine; Cholesterol, Dietary; Cricetinae; Diabetes Mellitus, Experimental; Gap Junctions; Heptanol; Hyperlipidemias; Male; Mesenteric Arteries; Mesocricetus; Nitroprusside; Norepinephrine; Potassium Chloride; Streptozocin; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats.
Topics: Animals; Arginine; Blood Glucose; Bone Density; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Experimental; Femur; Lysine; Male; Rats; Rats, Wistar; Stress, Mechanical; Vitamin B 6 | 2006 |
Relationship between protective effects of rosiglitazone on endothelium and endogenous nitric oxide synthase inhibitor in streptozotocin-induced diabetic rats and cultured endothelial cells.
Topics: Acetylcholine; Animals; Aorta; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Male; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Rosiglitazone; Thiazolidinediones; Tumor Necrosis Factor-alpha; Vasodilation | 2007 |
Simvastatin improves diabetes-induced coronary endothelial dysfunction.
Topics: Animals; Arginine; Coronary Vessels; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Simvastatin; Streptozocin; Superoxides; Tyrosine; Vasodilation | 2006 |
Pyridoxamine inhibits maillard reactions in diabetic rat lenses.
Topics: Aldehyde Reductase; Animals; Arginine; Chromatography, High Pressure Liquid; Diabetes Complications; Diabetes Mellitus, Experimental; Glucose; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lens Diseases; Lens, Crystalline; Lysine; Maillard Reaction; Male; Organ Culture Techniques; Ornithine; Pyridoxamine; Pyrimidines; Pyruvaldehyde; Rats; Rats, Sprague-Dawley | 2006 |
[Effect of L-arginine on diabetic rats].
Topics: Animals; Arginine; Blood Glucose; Blood Proteins; Body Weight; Diabetes Mellitus, Experimental; Drinking; Eating; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Lew | 2006 |
Asymmetric dimethylarginine reduced erythrocyte deformability in streptozotocin-induced diabetic rats.
Topics: Animals; Aorta, Thoracic; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Erythrocyte Deformability; In Vitro Techniques; Male; Malondialdehyde; Nitric Oxide; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Vitamin E | 2007 |
pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity.
Topics: 3T3-L1 Cells; Amino Acid Sequence; Amino Acids; Animals; Arginine; Binding, Competitive; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Dogs; Female; Humans; Hypoglycemic Agents; Insulin; Isoelectric Point; Lysine; Male; Mice; Molecular Sequence Data; Protein Binding; Radioimmunoassay; Receptor, IGF Type 1; Receptor, Insulin; Structure-Activity Relationship | 2007 |
Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis.
Topics: Animals; Aorta; Apolipoproteins E; Arginine; Atherosclerosis; Becaplermin; Cell Movement; Cell Proliferation; Cells, Cultured; Diabetes Complications; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Glyoxal; Guanidines; Humans; Mesoderm; Mice; Mice, Knockout; Myocytes, Smooth Muscle; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyruvaldehyde; Rabbits; Receptor, Platelet-Derived Growth Factor beta | 2007 |
Can nitric oxide-generating compounds improve the oxidative stress response in experimentally diabetic rats?
Topics: Animals; Antioxidants; Arginine; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Glyburide; Glycated Hemoglobin; Hypoglycemic Agents; Kidney; Linear Models; Lipid Peroxidation; Lipids; Liver; Male; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2007 |
The influence of L-arginine on blood pressure, vascular nitric oxide and renal morphometry in the offspring from diabetic mothers.
Topics: Acetylcholine; Administration, Oral; Animals; Arginine; Blood Pressure; Body Weight; Bradykinin; Diabetes Mellitus, Experimental; Dietary Supplements; Endothelium, Vascular; Female; Glomerular Filtration Rate; Hypertension; Hypertrophy; Kidney Diseases; Kidney Glomerulus; Nitric Oxide; Organ Size; Pregnancy; Pregnancy in Diabetics; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Time Factors; Vasodilator Agents | 2007 |
The role of nitric oxide in diabetes-induced changes of morphine tolerance in rats.
Topics: Analgesics, Opioid; Animals; Arginine; Diabetes Mellitus, Experimental; Drug Tolerance; Guanidines; Hot Temperature; Male; Morphine; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrites; Pain; Rats; Rats, Sprague-Dawley | 2007 |
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A.
Topics: Acetylglucosamine; Angiopoietin-2; Animals; Arginine; Cell Line, Transformed; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelial Cells; Gene Expression Regulation; Glucose; Glycolysis; Intercellular Adhesion Molecule-1; Kidney; Mice; N-Acetylglucosaminyltransferases; Protein Processing, Post-Translational; Pyruvaldehyde; Repressor Proteins; Response Elements; Sin3 Histone Deacetylase and Corepressor Complex; Sp3 Transcription Factor; Sweetening Agents; Transcription, Genetic; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1 | 2007 |
Beneficial effects of L-arginine nitric oxide-producing pathway in rats treated with alloxan.
Topics: Alloxan; Animals; Antioxidants; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression Regulation; Homeodomain Proteins; In Situ Nick-End Labeling; Insulin-Secreting Cells; Male; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Proliferating Cell Nuclear Antigen; Protein Isoforms; Rats; Trans-Activators | 2007 |
GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in
Topics: Amidohydrolases; Animals; Arginine; Catalysis; Diabetes Mellitus, Experimental; Dimethylamines; Enzyme Inhibitors; Female; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Liver; Male; Molecular Structure; Nitrates; Nitrites; Rats; Rats, Wistar; Reproducibility of Results; S-Nitrosothiols | 2007 |
Diabetic urethropathy compounds the effects of diabetic cystopathy.
Topics: Adrenergic alpha-Agonists; Animals; Antibiotics, Antineoplastic; Arginine; Bungarotoxins; Diabetes Mellitus, Experimental; Electromyography; Female; Follow-Up Studies; Muscle Contraction; Phenylephrine; Rats; Rats, Sprague-Dawley; Streptozocin; Urethra; Urethral Diseases; Urinary Bladder; Urinary Bladder Diseases | 2007 |
Diabetes-induced coronary vascular dysfunction involves increased arginase activity.
Topics: Animals; Arginase; Arginine; Binding, Competitive; Cattle; Coronary Disease; Coronary Vessels; Diabetes Complications; Diabetes Mellitus, Experimental; Endothelium, Vascular; Nitric Oxide Synthase Type III; Rats | 2008 |
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model.
Topics: Animals; Antimutagenic Agents; Arginine; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Blotting, Western; Chromatography, High Pressure Liquid; Cobalt; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Gene Expression; Glycation End Products, Advanced; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immediate-Early Proteins; Insulin-Like Growth Factor Binding Proteins; Intercellular Signaling Peptides and Proteins; Kidney; Lysine; Male; NADPH Oxidases; Obesity; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred SHR; RNA, Messenger; Transforming Growth Factor beta | 2008 |
Tubular and glomerular L-arginine transport (uptake and transporters) and the nitric oxide synthases in ischemic acute renal failure (iARF) in streptozotocin-induced diabetic rats (STZ-DM).
Topics: Acute Kidney Injury; Animals; Arginine; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Diabetes Mellitus, Experimental; Glyceraldehyde-3-Phosphate Dehydrogenases; Isoenzymes; Male; Nephrons; Nitric Oxide Synthase; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury; RNA, Messenger | 2007 |
L-arginine uptake in normal and diabetic rat retina and retinal pigment epithelium.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Nitrates; Nitric Oxide; Nitrites; Pigment Epithelium of Eye; Rats; Rats, Long-Evans; Retina | 2008 |
[Peculiarities of L-arginine metabolism in the blood leukocytes in experimental diabetes mellitus].
Topics: Animals; Arginase; Arginine; Diabetes Mellitus, Experimental; Guanidines; Leukocytes; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Substrate Specificity | 2008 |
Modulation of regional nitric oxide metabolism: blood glucose control or insulin?
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Nitric Oxide; Nitric Oxide Synthase; Parenteral Nutrition, Total; Rabbits | 2008 |
Somatostatin concentration responds to arginine in portal plasma: effects of fasting, streptozotocin diabetes, and insulin administration in diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Fasting; Insulin; Male; Rats; Somatostatin | 1980 |
Somatostatin release from the isolated, perfused diabetic rat pancreas: inverse relationship between pancreatic somatostatin and insulin.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Pancreas; Perfusion; Rats; Somatostatin | 1980 |
Reversal of the enhanced somatostatin release from the isolated, perfused diabetic rat pancreas after the amelioration of diabetes by whole pancreas transplantation.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Insulin; Kinetics; Male; Pancreas; Pancreas Transplantation; Rats; Somatostatin; Transplantation, Homologous | 1980 |
Acute effects of alloxan- and streptozotocin-induced insulin deficiency on somatostatin and glucagon secretion by the perfused isolated rat pancreatico-duodenal preparation.
Topics: Alloxan; Animals; Arginine; Diabetes Mellitus, Experimental; Duodenum; Glucagon; Glucose; Insulin; Male; Pancreas; Rats; Somatostatin; Streptozocin; Theophylline | 1981 |
Islet secretion in a new experimental model for non-insulin-dependent diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Male; Pregnancy; Rats; Somatostatin; Theophylline; Tolbutamide | 1981 |
Characterisation of the abnormal pancreatic D and A cell function in streptozotocin diabetic dogs: studies with D-glyceraldehyde, dihydroxyacetone, D-mannoheptulose, D-glucose, and L-arginine.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Dihydroxyacetone; Dogs; Glucagon; Glucose; Glyceraldehyde; Heptoses; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Mannoheptulose; Somatostatin; Trioses | 1981 |
Changes in somatostatin release from perfused pancreas of streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Body Weight; Diabetes Mellitus, Experimental; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains; Somatostatin | 1981 |
Loss of a priming effect of glucose on A and D cell secretion in perfused pancreases from alloxan-diabetic rats: role of insulin and alloxan.
Topics: Alloxan; Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreatic Hormones; Perfusion; Rats; Rats, Inbred Strains; Somatostatin | 1983 |
Abnormal amino acid concentrations in plasma and urine of experimentally diabetic dogs.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Female; Glutamates; Glutamic Acid; Histidine; Male; Phenylalanine; Renal Aminoacidurias; Tryptophan; Tyrosine | 1983 |
Somatostatin, glucagon, and insulin secretion from perfused pancreas of BB rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Rats; Rats, Mutant Strains; Somatostatin; Theophylline | 1984 |
Insulin, glucagon, and somatostatin release from the prediabetic Chinese hamster.
Topics: Aging; Animals; Arginine; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mutation; Prediabetic State; Somatostatin | 1984 |
Abnormal glucose regulation of insulin secretion in models of reduced B-cell mass.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreatectomy; Perfusion; Radioimmunoassay; Rats; Rats, Inbred Strains; Streptozocin | 1984 |
Effect of islet-activating protein (IAP), purified from the culture medium of Bordetella pertussis, on the secretion of immunoreactive insulin and glucagon in normal, alloxan-treated, and depancreatized dogs.
Topics: Alloxan; Animals; Arginine; Bacterial Proteins; Blood Glucose; Bordetella pertussis; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Pancreatectomy; Pertussis Toxin; Virulence Factors, Bordetella | 1981 |
Glucose insensitivity and amino-acid hypersensitivity of insulin release in rats with non-insulin-dependent diabetes. A study with the perfused pancreas.
Topics: Acetylcholine; Amino Acids; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glyceraldehyde; Insulin; Insulin Secretion; Islets of Langerhans; Isoproterenol; Keto Acids; Leucine; Mannose; Rats; Rats, Inbred Strains; Theophylline; Tolbutamide | 1983 |
Glucose- and arginine-induced insulin and glucagon responses from the isolated perfused pancreas of the BB-Wistar diabetic rat. Evidence for selective impairment of glucose regulation.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Perfusion; Rats; Rats, Inbred Strains | 1983 |
Clinical forms and natural history of the diabetic syndrome and insulin and glucagon secretion in the BB rat.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Glucagon; Insulin; Insulin Secretion; Male; Rats; Rats, Inbred Strains; Stress, Physiological; Tolbutamide | 1983 |
Evidence for insulin involvement in arginine- and glucose-induced hypercalciuria in the rat.
Topics: Animals; Arginine; Calcium; Diabetes Mellitus, Experimental; Female; Glomerular Filtration Rate; Glucose; Insulin; Mannoheptulose; Rats; Rats, Inbred Strains | 1983 |
Glucagon secretory responses to insulin-induced hypoglycemia and arginine in streptozotocin-induced diabetic dogs.
Topics: Animals; Arginine; Cell Communication; Diabetes Mellitus, Experimental; Dogs; Female; Glucagon; Hypoglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male | 1983 |
Insulin, glucagon, and somatostatin secretion from isolated perfused rat and chicken pancreas-duodenum.
Topics: Animals; Arginine; Chickens; Diabetes Mellitus, Experimental; Duodenum; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Radioimmunoassay; Rats; Somatostatin; Streptozocin | 1980 |
Glucagon secretion in rats with non-insulin-dependent diabetes: an in vivo and in vitro study.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucagon; In Vitro Techniques; Male; Pancreas; Rats; Rats, Inbred Strains | 1984 |
Impaired insulin secretion in the spontaneous diabetes rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Norepinephrine; Rats | 1982 |
Portal vein insulin response of glucose intolerant Yucatan miniature swine to common secretogogues.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Glucose Tolerance Test; Insulin; Isoproterenol; Leucine; Male; Portal Vein; Swine; Swine, Miniature | 1982 |
[Disparity between the effect of glucose and arginine on insulin secretion from the perfused pancreas of non insulin dependent diabetic rats].
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains | 1981 |
Arginine-induced glucagon secretion in the spontaneously diabetic BB Wistar rat.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucagon; Male; Rats; Rats, Inbred Strains | 1983 |
Metasomatotrophic diabetes and its induction: basal insulin secretion and insulin release responses to glucose, glucagon, arginine and meals.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Eating; Fasting; Glucagon; Glucose; Glucose Tolerance Test; Growth Hormone; Insulin; Insulin Secretion; Kinetics; Male | 1980 |
Glucagon in spontaneously diabetic KK mice.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glucagon; Hyperglycemia; Insulin; Jejunum; Male; Mice; Organ Size; Pancreas; Stomach | 1981 |
Formation of arginine and guanidinoacetic acid in the kidney in vivo. Their relations with the liver and their regulation.
Topics: Animals; Arginine; Citrulline; Diabetes Mellitus, Experimental; Diet; Glycine; Hepatectomy; Insulin; Kidney; Male; Nephrectomy; Ornithine; Rats | 1981 |
Potassium ion concentration alters glucagon secretion independently of insulin secretion in the isolated rat pancreas.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Perfusion; Potassium; Rats; Rats, Inbred Strains | 1982 |
Insulin and glucagon release in the diabetic Chinese hamster: differences among inbred sublines.
Topics: Animals; Arginine; Blood Glucose; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Female; Glucagon; Glucose; Insulin; Male; Pancreas; Perfusion; Sex Factors; Species Specificity | 1982 |
Effect of streptozotocin diabetes on some urea cycle enzymes.
Topics: Acetyltransferases; Amidohydrolases; Amino-Acid N-Acetyltransferase; Animals; Arginine; Carbamoyl-Phosphate Synthase (Ammonia); Diabetes Mellitus, Experimental; Ligases; Liver; Male; Mitochondria, Liver; Ornithine Carbamoyltransferase; Rats; Rats, Inbred Strains; Urea | 1982 |
Effect of endothelium on diabetes-induced changes in constrictor responses mediated by 5-hydroxytryptamine in rat aorta.
Topics: Amphetamines; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Endothelium; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroarginine; Organ Size; Papaverine; Potassium; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Vasoconstriction | 1993 |
Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Alkaloids; Amino Acid Oxidoreductases; Animals; Arginine; Calcimycin; Carbachol; Cyclic GMP; Diabetes Mellitus, Experimental; Female; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kidney Glomerulus; Kinetics; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Phosphates; Phosphorylation; Piperazines; Prostaglandin Endoperoxides, Synthetic; Protein Kinase C; Proteins; Rats; Rats, Sprague-Dawley; Staurosporine; Thromboxane A2 | 1994 |
Abnormal renal hemodynamic response to reduced renal perfusion pressure in diabetic rats: role of NO.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Hemodynamics; Homeostasis; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renal Circulation; Vascular Resistance | 1993 |
Inhibition of nitric oxide synthase by NG-nitro-L-arginine causes a preferential decrease in pancreatic islet blood flow in normal rats and spontaneously diabetic GK rats.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Diabetes Mellitus, Experimental; Female; Islets of Langerhans; Male; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Rats, Wistar; Reference Values; Regional Blood Flow | 1994 |
Interleukin 1 beta induces diabetes and fever in normal rats by nitric oxide via induction of different nitric oxide synthases.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Body Temperature; Body Weight; Corticosterone; Diabetes Mellitus, Experimental; Glucagon; Guanidines; Humans; Insulin; Interleukin-1; Isoenzymes; Leukocyte Count; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred WKY; Recombinant Proteins; Weight Gain | 1994 |
Expression of intrahepatic inducible nitric oxide synthetase mRNA correlates with production of nitric oxide during intraportal isogeneic and allogeneic rat islet transplantation.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Diabetes Mellitus, Experimental; Enzyme Induction; Gene Expression; Graft Rejection; Islets of Langerhans Transplantation; Liver; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Polymerase Chain Reaction; Portal System; Rats; Rats, Inbred Lew; Rats, Wistar; RNA, Messenger; T-Lymphocytes; Time Factors; Transplantation, Homologous; Transplantation, Isogeneic | 1995 |
Impairment of nitrergic-mediated relaxation of rat isolated duodenum by experimental diabetes.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Arginine; Citrulline; Diabetes Mellitus, Experimental; Dimethylphenylpiperazinium Iodide; Duodenum; In Vitro Techniques; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Rats; Rats, Wistar; Tissue Preservation | 1995 |
Impaired vasoreactivity to nitric oxide in experimental diabetic neuropathy.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Arterioles; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Endothelins; Endothelium, Vascular; Microcirculation; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reference Values; Sciatic Nerve | 1995 |
Nitric oxide is important for mouse beta-cell line killing by peritoneal exudate cells obtained from cyclophosphamide treated non-obese diabetic mice.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Cell Death; Cell Line; Cyclophosphamide; Cytotoxicity, Immunologic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female; Islets of Langerhans; Macrophages, Peritoneal; Mice; Mice, Inbred NOD; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine | 1995 |
Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation.
Topics: Aldehyde Reductase; Amino Acid Oxidoreductases; Animals; Arginine; Benzothiazoles; Blood Pressure; Body Weight; Capillary Permeability; Citrulline; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glycation End Products, Advanced; Guanidines; Imidazoles; Imidazolidines; Inositol; Iodine Radioisotopes; Male; Methylguanidine; Naphthalenes; Nitric Oxide Synthase; omega-N-Methylarginine; Phthalazines; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Serum Albumin, Bovine; Sorbitol; Thiazoles; Uvea | 1993 |
Altered vascular permeability responses to substance P in diabetic rats: interactions with a nitric oxide synthesis inhibitor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Blood Pressure; Capillary Permeability; Diabetes Mellitus, Experimental; Dinoprostone; Drinking; Injections, Intravenous; Male; Nitric Oxide Synthase; Nitroarginine; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Substance P | 1993 |
Endothelium-derived hyperpolarizing factor does not contribute to the decrease in endothelium-dependent relaxation in the aorta of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Biological Factors; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Streptozocin; Tetraethylammonium Compounds; Vasodilation | 1995 |
Salivary peptide P-C potentiates insulin release and inhibits glucagon release from isolated perfused pancreas of the diabetic GK rat.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Immunohistochemistry; Insulin; Insulin Secretion; Male; Pancreas; Peptides; Rats; Rats, Wistar | 1995 |
Streptozotocin-induced hyperglycemia is decreased by nitric oxide inhibition.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diuresis; Hyperglycemia; Kallikreins; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitroarginine; Proteinuria; Time Factors | 1994 |
Superoxide dismutase restores the influence of nitric oxide on renal arterioles in diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Diabetes Mellitus, Experimental; Male; Nitric Oxide; Nitroarginine; Rats; Renal Circulation; Superoxide Dismutase; Vasodilation | 1995 |
Amelioration by L-arginine of a dysfunctional arginine/nitric oxide pathway in diabetic endothelium.
Topics: Acetylcholine; Amino Acids; Animals; Arginine; Body Weight; Calcimycin; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley | 1995 |
Age-related changes in vascular reactivity in genetically diabetic rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Calcimycin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker | 1995 |
The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Hyperglycemia; In Vitro Techniques; Indomethacin; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Phthalazines; Rats; Rats, Wistar; Vasodilation | 1994 |
Administration of NG-monomethyl-L-arginine in a marginal renal subcapsular mouse islet transplant model.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Drug Administration Schedule; Infusions, Parenteral; Injections, Intraperitoneal; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Transplantation, Heterotopic; Transplantation, Isogeneic | 1995 |
Defective insulin and glucagon secretion in isolated perfused pancreata of diabetic WBN/Kob rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Susceptibility; Glucagon; Glucose Tolerance Test; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Rats; Rats, Inbred Strains; Rats, Wistar | 1995 |
Role of endothelium-derived nitric oxide in the pathogenesis of the renal hemodynamic changes of experimental diabetes.
Topics: Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hemodynamics; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Renal Circulation | 1994 |
Gliclazide directly suppresses arginine-induced glucagon secretion.
Topics: Animals; Arginine; Cysteamine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Gliclazide; Glucagon; Insulin; Insulin Secretion; Male; Pancreas; Rats; Rats, Wistar; Somatostatin; Streptozocin; Sulfonylurea Compounds | 1994 |
Administration of L-GN-monomethyl-arginine in a mouse islet transplant model.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Nitric Oxide; omega-N-Methylarginine; Transplantation, Heterotopic | 1994 |
Prevention by insulin treatment of endothelial dysfunction but not enhanced noradrenaline-induced contractility in mesenteric resistance arteries from streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Arginine; Delayed-Action Preparations; Diabetes Mellitus, Experimental; Drug Implants; Endothelium, Vascular; Female; Insulin; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Rats; Rats, Wistar; Vascular Resistance | 1994 |
Attenuated 5-hydroxytryptamine receptor-mediated responses in aortae from streptozotocin-induced diabetic rats.
Topics: Animals; Aorta; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Endothelium, Vascular; Insulin; Ketanserin; Male; Nitroarginine; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Vasoconstriction | 1994 |
The linked roles of nitric oxide, aldose reductase and, (Na+,K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat.
Topics: Aldehyde Reductase; Animals; Arginine; Diabetes Mellitus, Experimental; Male; Neural Conduction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Streptozocin | 1994 |
Diabetes-induced endothelial dysfunction in streptozotocin-treated rats: role of prostaglandin endoperoxides and free radicals.
Topics: Animals; Arginine; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelium, Vascular; Fatty Acids, Unsaturated; Free Radical Scavengers; Free Radicals; Hydrazines; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandin Endoperoxides; Rats; Rats, Inbred WKY; Receptors, Thromboxane; Renal Artery; Superoxide Dismutase; Thiourea; Vasodilation | 1993 |
Antinociceptive effect of L-arginine in diabetic mice.
Topics: Analgesics; Animals; Arginine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endorphins; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nitroarginine; Pain Measurement; Reaction Time | 1994 |
Selective impairment of the cytoplasmic Ca2+ response to glucose in pancreatic beta cells of streptozocin-induced non-insulin-dependent diabetic rats.
Topics: Animals; Animals, Newborn; Arginine; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Wistar; Streptozocin; Time Factors | 1993 |
Responses of cerebral arterioles to activation of beta-adrenergic receptors during diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Cerebrovascular Circulation; Colforsin; Diabetes Mellitus, Experimental; Isoproterenol; Nitric Oxide; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Rats; Receptors, Adrenergic, beta; Vasodilation | 1994 |
Effects of haemoglobin and N-nitro-L-arginine on constrictor and dilator responses of aortic rings from streptozotocin diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Hemoglobins; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Vasoconstriction; Vasodilation | 1993 |
L-arginine administration prevents glomerular hyperfiltration and decreases proteinuria in diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Kidney; Nitric Oxide; Proteinuria; Rats; Rats, Sprague-Dawley; Renal Circulation | 1993 |
Diazoxide causes recovery of beta-cell glucose responsiveness in 90% pancreatectomized diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diazoxide; Glucose; Glucose Tolerance Test; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreatectomy; Perfusion; Rats; Rats, Sprague-Dawley | 1994 |
Spontaneous glucose intolerance in the progeny of low dose streptozotocin-induced diabetic mice.
Topics: Aging; Animals; Arginine; Body Weight; Diabetes Mellitus, Experimental; Female; Glucose; Glucose Intolerance; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Pancreatic Diseases; Pregnancy; Pregnancy in Diabetics; Sex Factors; Species Specificity | 1993 |
Role of EDRF (nitric oxide) in diabetic renal hyperfiltration.
Topics: Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Sprague-Dawley; Renal Circulation | 1993 |
Pharmacological manipulation of vascular endothelium function in non-diabetic and streptozotocin-diabetic rats: effects on nerve conduction, hypoxic resistance and endoneurial capillarization.
Topics: Animals; Arginine; Capillaries; Cell Hypoxia; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Endothelium, Vascular; Flurbiprofen; In Vitro Techniques; Male; Motor Neurons; Neural Conduction; Neurons, Afferent; Nitroarginine; Peripheral Nerves; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Sciatic Nerve | 1993 |
Responses of cerebral arterioles in diabetic rats to activation of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Arginine; Arterioles; Cerebrovascular Circulation; Diabetes Mellitus, Experimental; Male; Nitroglycerin; omega-N-Methylarginine; Pia Mater; Picolines; Potassium Channels; Pyrans; Rats; Rats, Sprague-Dawley | 1993 |
Changes in endothelium-dependent relaxation and levels of cyclic nucleotides in the perfused mesenteric arterial bed from streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Blood Pressure; Cyclic AMP; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Vasodilation | 1993 |
GLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats.
Topics: 3-O-Methylglucose; Animals; Arginine; Biological Transport; Blood Glucose; Dexamethasone; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Transporter Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Methylglucosides; Mifepristone; Monosaccharide Transport Proteins; Rats; Rats, Zucker | 1993 |
Insulin secretory function in relation to transplanted islet mass in STZ-induced diabetic rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Rats; Rats, Inbred WF; Time Factors | 1993 |
Effect of diabetes on relaxations to non-adrenergic, non-cholinergic nerve stimulation in longitudinal muscle of the rat gastric fundus.
Topics: Adrenergic Fibers; Animals; Arginine; Blood Glucose; Cholinergic Fibers; Diabetes Mellitus, Experimental; Electric Stimulation; Gastric Fundus; In Vitro Techniques; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vasoactive Intestinal Peptide | 1995 |
Administration of a nitric oxide synthase inhibitor does not suppress low-dose streptozotocin-induced diabetes in mice.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Islets of Langerhans; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Streptozocin | 1995 |
Evidence of a glycemic threshold for the formation of pentosidine in diabetic dog lens but not in collagen.
Topics: Animals; Arginine; Blood Glucose; Blood Proteins; Chromatography, High Pressure Liquid; Collagen; Diabetes Mellitus, Experimental; Dogs; Dura Mater; Female; Glycated Hemoglobin; Glycated Serum Proteins; Glycation End Products, Advanced; Glycoproteins; Glycosuria; Glycosylation; Lens, Crystalline; Lysine; Male; Reference Values | 1996 |
L-Arginine does not restore dilatation of the basilar artery during diabetes mellitus.
Topics: Acetylcholine; Animals; Arginine; Basilar Artery; Bradykinin; Diabetes Mellitus, Experimental; Male; Nitroglycerin; Rats; Rats, Sprague-Dawley; Reference Values; Vasodilation | 1996 |
Interactions between essential fatty acid, prostanoid, polyol pathway and nitric oxide mechanisms in the neurovascular deficit of diabetic rats.
Topics: Acetanilides; Aldehyde Reductase; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dietary Fats, Unsaturated; Enzyme Inhibitors; Erythropoietin; Fatty Acids, Essential; Flurbiprofen; Fructose; gamma-Linolenic Acid; Inositol; Linoleic Acids; Male; Neural Conduction; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oenothera biennis; Plant Oils; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Regression Analysis; Sciatic Nerve; Sorbitol; Sulfones | 1996 |
Nitric oxide in streptozotocin-induced diabetes mellitus in rats.
Topics: Alloxan; Animals; Arginine; Creatine; Diabetes Mellitus, Experimental; Metabolic Clearance Rate; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Rats; Rats, Wistar | 1996 |
Deficient nitric oxide responsible for reduced nerve blood flow in diabetic rats: effects of L-NAME, L-arginine, sodium nitroprusside and evening primrose oil.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Enzyme Activation; Enzyme Inhibitors; Fatty Acids, Essential; gamma-Linolenic Acid; Guanylate Cyclase; Linoleic Acids; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Oenothera biennis; Plant Oils; Rats; Sciatic Nerve; Vasodilator Agents | 1996 |
Diabetes-mediated decreases in ovarian superoxide dismutase activity are related to blood-follicle barrier and ovulation defects.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Arginine; Capillary Permeability; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Endothelium, Vascular; Female; Free Radical Scavengers; Gonadotropins, Equine; Insulin; Intercellular Junctions; Isoenzymes; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Ovarian Follicle; Ovary; Ovulation; Reference Values; Superoxide Dismutase; Thiophenes | 1996 |
Rapid reversal by aminoguanidine of the neurovascular effects of diabetes in rats: modulation by nitric oxide synthase inhibition.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Diabetic Neuropathies; Enzyme Inhibitors; Glycation End Products, Advanced; Guanidines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1996 |
Nitric oxide in ischaemic acute renal failure of streptozotocin diabetic rats.
Topics: Acute Kidney Injury; Analysis of Variance; Animals; Arginine; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Ischemia; Nephrectomy; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Rats; Rats, Wistar; Reference Values; Renal Artery; Renal Circulation; Sodium | 1996 |
Renal effects of acute and chronic nitric oxide inhibition in experimental diabetes.
Topics: Angiotensin II; Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Endothelin-1; Enzyme Inhibitors; Glomerular Filtration Rate; Hemodynamics; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation; Time Factors | 1996 |
Short-term oral administration of L-arginine reverses defective endothelium-dependent relaxation and cGMP generation in diabetes.
Topics: Acetylcholine; Amino Acids; Animals; Aorta, Thoracic; Arginine; Blood Glucose; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley | 1996 |
Aminoguanidine--effects on endoneurial vasoactive nitric oxide and on motor nerve conduction velocity in control and streptozotocin-diabetic rats.
Topics: Amine Oxidase (Copper-Containing); Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Guanidines; Heart Rate; Laser-Doppler Flowmetry; Male; Neural Conduction; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Sciatic Nerve; Streptozocin | 1997 |
Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands.
Topics: Animals; Arginine; Citrulline; Cyclic GMP; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Exocrine Glands; Gastric Mucosa; Hypoglycemic Agents; Insulin; Kinetics; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rabbits | 1997 |
Imidazolone, a novel advanced glycation end product, is present at high levels in kidneys of rats with streptozotocin-induced diabetes.
Topics: Animals; Antibodies, Monoclonal; Arginine; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Glycation End Products, Advanced; Imidazoles; Kidney; Kinetics; Maillard Reaction; Male; Mice; Rats; Rats, Wistar | 1997 |
Characteristics of coronary endothelial dysfunction in experimental diabetes.
Topics: Acetylcholine; Animals; Arginine; Coronary Circulation; Coronary Vessels; Cyclic GMP; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Dogs; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Ibuprofen; In Vitro Techniques; Indomethacin; Male; Nitric Oxide; Nitroprusside; Vasodilation; Vasodilator Agents | 1997 |
L-arginine does not reverse impaired agonist-induced increases in macromolecular efflux during diabetes mellitus.
Topics: Animals; Arginine; Capillary Permeability; Cheek; Cricetinae; Dextrans; Diabetes Mellitus, Experimental; Extravasation of Diagnostic and Therapeutic Materials; Fluorescein-5-isothiocyanate; Histamine; Inflammation Mediators; Macromolecular Substances; Male; Mesocricetus; Substance P | 1997 |
Delayed Ca2+ response to glucose in diabetic GK rat.
Topics: Animals; Arginine; Calcium; Cells, Cultured; Diabetes Mellitus, Experimental; Glucose; Islets of Langerhans; Rats; Rats, Inbred Strains; Rats, Wistar | 1997 |
Inhibition of platelet aggregation by L-arginine and polyamines in alloxan treated rats.
Topics: Animals; Arginase; Arginine; Diabetes Mellitus, Experimental; Humans; Insulin; Male; Plasma; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyamines; Putrescine; Rats; Rats, Sprague-Dawley; Spermidine; Spermine | 1997 |
Plasma and vascular tissue arginine are decreased in diabetes: acute arginine supplementation restores endothelium-dependent relaxation by augmenting cGMP production.
Topics: Animals; Arginine; Body Weight; Cyclic GMP; Diabetes Mellitus, Experimental; Endothelium, Vascular; Male; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin; Vasodilation | 1997 |
Nitric oxide synthase activity and L-arginine metabolism in the retinas from streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Retina; Streptozocin | 1998 |
Study of I-arginine: no pathway before and after low-dose Escherichia coli lipopolysaccharide in normal, diabetic, and islet transplanted rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Escherichia coli; Islets of Langerhans Transplantation; Lipopolysaccharides; Male; Nitric Oxide; Rats; Rats, Wistar; Signal Transduction | 1998 |
Transplantation of syngenic pancreatic islets into rats with streptozotocin induced non insulin dependent diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Rats; Rats, Inbred Lew; Transplantation, Isogeneic | 1997 |
Circulating advanced glycation peptides in streptozotocin-induced diabetic rats: evidence for preferential modification of IgG light chains.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Guanidines; Immunoglobulin Light Chains; Lysine; Male; Peptide Fragments; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence | 1998 |
Pancreatic beta-cell regeneration after 48-h glucose infusion in mildly diabetic rats is not correlated with functional improvement.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; Hyperinsulinism; Immunoenzyme Techniques; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Leucine; Male; Rats; Rats, Wistar; Regeneration | 1998 |
Reduced nerve blood flow in diabetic rats: relationship to nitric oxide production and inhibition of aldose reductase.
Topics: Aldehyde Reductase; Animals; Arginine; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Laser-Doppler Flowmetry; Male; Motor Neurons; Neural Conduction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Wistar; Sciatic Nerve | 1998 |
Effects of L-NAME and L-Arg on arterial blood pressure in normotensive and hypertensive streptozotocin diabetic rats.
Topics: Analysis of Variance; Animals; Arginine; Blood Pressure; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Hemodynamics; Hypertension; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Streptozocin | 1998 |
Impaired phasic insulin and amylin secretion in diabetic rats.
Topics: Activity Cycles; Amyloid; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Hypoglycemic Agents; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Pancreatectomy; Rats; Rats, Sprague-Dawley; Tolbutamide | 1998 |
Effect of L-arginine-nitric oxide system on chemical-induced diabetes mellitus.
Topics: Alloxan; Animals; Antioxidants; Arginine; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Insulin; Ketone Bodies; Lactic Acid; Lipid Peroxides; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Wistar | 1998 |
Impairment of nitric oxide-mediated relaxations in anaesthetized autoperfused streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Anesthesia; Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Enzyme Inhibitors; Free Radical Scavengers; Glycated Hemoglobin; Heart Rate; Hindlimb; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Perfusion; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 1998 |
Interactions between vitamin E and glucose on B-cell functions in the rat: an in vivo and in vitro study.
Topics: Animals; Arginine; Cells, Cultured; Diabetes Mellitus, Experimental; Drug Interactions; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Kidney; Male; Proinsulin; Protein Precursors; Rats; Rats, Inbred WF; Rats, Wistar; RNA; RNA, Messenger; Transplantation, Heterotopic; Vitamin E | 1999 |
Aminoguanidine inhibits albuminuria, but not the formation of advanced glycation end-products in skin collagen of diabetic rats.
Topics: Albuminuria; Animals; Arginine; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glycated Hemoglobin; Glycation End Products, Advanced; Guanidines; Kinetics; Lysine; Male; Metabolic Clearance Rate; Rats; Rats, Inbred Lew; Reference Values; Skin | 1999 |
Antinociceptive mechanism of Gosha-jinki-gan in streptozotocin-induced diabetic animals: role of nitric oxide in the periphery.
Topics: Analgesics; Animals; Arginine; Diabetes Mellitus, Experimental; Drugs, Chinese Herbal; Enzyme Inhibitors; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Tail | 1999 |
The effects of long-term oral administration of L-arginine on the erectile response of rabbits with alloxan-induced diabetes.
Topics: Administration, Oral; Animals; Arginine; Diabetes Mellitus, Experimental; Isometric Contraction; Male; Muscle Relaxation; Muscle, Smooth; Penile Erection; Rabbits | 1999 |
Elevation of an endogenous inhibitor of nitric oxide synthase in diabetic rat serum.
Topics: Animals; Aorta; Arginine; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Vasodilation | 1997 |
Pancreatic secretory responses in L-arginine-induced pancreatitis: comparison of diabetic and nondiabetic rats.
Topics: Acute Disease; Amylases; Animals; Arginine; Diabetes Mellitus, Experimental; Male; Pancreas; Pancreatic Juice; Pancreatitis; Rats; Rats, Wistar; Sincalide; Time Factors | 1999 |
Effect of early stage of experimental diabetes on vascular functions in isolated perfused kidneys.
Topics: Animals; Arginine; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Fructosamine; Glycated Hemoglobin; Male; Nitric Oxide; Nitroprusside; Norepinephrine; Perfusion; Phenylephrine; Random Allocation; Rats; Rats, Wistar; Renal Insufficiency; Time Factors; Vascular Resistance; Vasodilator Agents | 1999 |
Effects of cryopreservation on in vitro and in vivo long-term function of human islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Cryopreservation; Diabetes Mellitus, Experimental; Glucagon; Glucose; Glucose Tolerance Test; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Nude; Reference Values; Time Factors; Transplantation, Heterologous | 1999 |
Regulation of uveal and retinal blood flow in STZ-diabetic and non-diabetic rats; involvement of nitric oxide.
Topics: Acetylcholine; Animals; Arginine; Blood Flow Velocity; Choroid; Diabetes Mellitus, Experimental; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Retinal Vessels; Uvea; Vascular Resistance; Vasodilation | 1999 |
The effects of chronic L-arginine treatment on vascular responsiveness of streptozotocin-diabetic rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Eating; Endothelium, Vascular; In Vitro Techniques; Male; Nitroprusside; Norepinephrine; Rats; Rats, Wistar; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 1999 |
The effects of long-term oral L-arginine on the erectile response of rabbits with alloxan-induced diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Impotence, Vasculogenic; Male; Penile Erection; Rabbits | 1999 |
The effects of long-term oral L-arginine on the erectile response of rabbits with alloxan-induced diabetes.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Humans; Impotence, Vasculogenic; Male; Penile Erection; Rabbits | 1999 |
Reversal effects of L-arginine treatment on blood pressure and vascular responsiveness of streptozotocin-diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Blood Vessels; Body Weight; Diabetes Mellitus, Experimental; Endothelium, Vascular; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Wistar; Time Factors; Vasoconstrictor Agents; Vasodilator Agents | 2000 |
[L-arginine and nitric oxide have effects on glomerulus hyperperfusion of early diabetic rats].
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glomerular Filtration Rate; Kidney; Male; Nitric Oxide; Rats; Rats, Wistar | 1997 |
Impaired endothelium-dependent and neurogenic relaxation of corpus cavernosum from diabetic rats: improvement with L-arginine.
Topics: Acetylcholine; Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium; Male; Muscle Relaxation; Muscle, Smooth; Penis; Rats; Rats, Wistar; Vasodilator Agents | 2000 |
L-arginine transport in retinas from streptozotocin diabetic rats: correlation with the level of IL-1 beta and NO synthase activity.
Topics: Animals; Arginine; Biological Transport; Diabetes Mellitus, Experimental; Hydrogen-Ion Concentration; Interleukin-1; Male; Nitric Oxide Synthase; Rats; Rats, Wistar; Retina | 1999 |
The effects of chronic L-name and L-arginine administration on beta-adrenergic responsiveness of STZ-diabetic rat atria.
Topics: Animals; Arginine; Body Weight; Diabetes Mellitus, Experimental; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Rats; Receptors, Adrenergic, beta; Streptozocin | 2000 |
Effect of L-arginine-nitric oxide system on the metabolism of essential fatty acids in chemical-induced diabetes mellitus.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arginine; Delta-5 Fatty Acid Desaturase; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fatty Acid Desaturases; Fatty Acids, Essential; gamma-Linolenic Acid; Linoleic Acid; Linoleoyl-CoA Desaturase; Lipid Peroxides; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Phospholipids; Rats; Rats, Wistar | 2000 |
The effects of simultaneous hyperlipemia-hyperglycemia on the resistance arteries, myocardium and kidney glomeruli.
Topics: Acetylcholine; Animals; Arginine; Blood Glucose; Cholesterol; Cholesterol, Dietary; Collagen; Cricetinae; Diabetes Mellitus, Experimental; Erythrocytes; Glomerular Mesangium; Glycation End Products, Advanced; Hyperlipidemias; Hypertrophy, Left Ventricular; Lysine; Male; Mesenteric Arteries; Mesocricetus; Myocardium; Norepinephrine; Osmotic Fragility; Peptidyl-Dipeptidase A; Vascular Resistance | 2000 |
Eicosapentaenoic acid stimulates nitric oxide production and decreases cardiac noradrenaline in diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Eicosapentaenoic Acid; Enzyme Inhibitors; Fructosamine; Heart; Heart Rate; Insulin; Male; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Rats; Rats, Wistar; Sympathetic Nervous System | 2000 |
Nitric oxide synthase activity in retinas from non-insulin-dependent diabetic Goto-Kakizaki rats: correlation with blood-retinal barrier permeability.
Topics: Animals; Arginine; Blood Glucose; Blood-Retinal Barrier; Blotting, Western; Densitometry; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Fluorescein Angiography; Guanidines; Immunohistochemistry; Interleukin-1; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitroarginine; Rats; Rats, Inbred Strains; Rats, Wistar; Retina; Retinal Vessels | 2000 |
Insulin restores neuronal nitric oxide synthase expression in streptozotocin-induced diabetic rats.
Topics: Animals; Arginine; Blood Glucose; Blotting, Northern; Blotting, Western; Citrulline; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2000 |
Role of nitric oxide in renal function in rats with short and prolonged periods of streptozotocin-induced diabetes.
Topics: Animals; Arginine; Blood Flow Velocity; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diuresis; Enzyme Inhibitors; Glomerular Filtration Rate; Glycosuria; Insulin; Kidney; Kidney Tubules; Male; Natriuresis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Proteinuria; Rats; Rats, Wistar | 1999 |
High glucose induces ventricular instability and increases vasomotor tone in rats.
Topics: Animals; Arginine; Blood Pressure; Coronary Circulation; Diabetes Mellitus, Experimental; Electrocardiography; Enzyme Inhibitors; Glutathione; Heart; Heart Rate; Heart Ventricles; Hyperglycemia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Vasomotor System | 2001 |
Regulation of hyperglycemia and dyslipidemia by exogenous L-arginine in diabetic rats.
Topics: Animals; Aorta; Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Arginine; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Glucose; Hyperglycemia; Hyperlipidemias; Lipoproteins, HDL; Lipoproteins, LDL; Male; Rats; Rats, Sprague-Dawley; Time Factors; Triglycerides | 2001 |
Coinduction of endothelial nitric oxide synthase and arginine recycling enzymes in aorta of diabetic rats.
Topics: Amino Acid Transport Systems, Basic; Animals; Aorta; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Blood Glucose; Carrier Proteins; Cell Division; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Insulin; Liver; Male; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Umbilical Veins | 2001 |
Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin.
Topics: Albumins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Aspirin; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dogs; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosuria; Guanidines; Kidney; Lysine; Neural Conduction; Platelet Aggregation; Random Allocation; Retinal Vessels; Ulnar Nerve | 2001 |
N-phenacylthiazolium bromide decreases renal and increases urinary advanced glycation end products excretion without ameliorating diabetic nephropathy in C57BL/6 mice.
Topics: Animals; Arginine; Collagen; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Mesangium; Glycation End Products, Advanced; Kidney; Kidney Glomerulus; Lysine; Mice; Mice, Inbred C57BL; Proteinuria; Thiazoles | 2001 |
L-arginine stimulates insulin secretion from the pancreas of normal and diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Humans; In Vitro Techniques; Insulin; Insulin Secretion; Male; Nitric Oxide Donors; Pancreas; Radioimmunoassay; Rats; Rats, Wistar | 2001 |
Insulin secretion to glucose as well as nonglucose stimuli is impaired in spontaneously diabetic Nagoya-Shibata-Yasuda mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Arginine; Blood Glucose; Calcium Channel Agonists; Cell Separation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glucose Tolerance Test; Glyburide; Hypoglycemic Agents; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Stimulation, Chemical | 2001 |
Differential impairment of glucagon responses to hypoglycemia, neuroglycopenia, arginine, and carbachol in alloxan-diabetic mice.
Topics: Animals; Arginine; Brain; Carbachol; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucagon; Glucose; Hypoglycemia; Hypoglycemic Agents; Insulin; Mice; Mice, Inbred Strains | 2002 |
Effect of treating streptozotocin-induced diabetic rats with sorbinil, myo-inositol or aminoguanidine on endoneurial blood flow, motor nerve conduction velocity and vascular function of epineurial arterioles of the sciatic nerve.
Topics: Aldehyde Reductase; Animals; Arginine; Arterioles; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Guanidines; Imidazoles; Imidazolidines; Inositol; Lysine; Male; Neural Conduction; Rats; Rats, Sprague-Dawley; Retina; Sciatic Nerve; Sodium-Potassium-Exchanging ATPase; Superoxides | 2002 |
Mild streptozotocin diabetes in the Göttingen minipig. A novel model of moderate insulin deficiency and diabetes.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Fasting; Food; Glucagon; Glucose Tolerance Test; Insulin; Insulin Secretion; Islets of Langerhans; Male; Niacinamide; Streptozocin; Swine, Miniature; Time Factors | 2002 |
Isolation, transplantation, and functional studies of adult porcine islets of Langerhans.
Topics: Animals; Arginine; Cell Separation; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; DNA; Glucose; Humans; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Nude; Swine | 2002 |
Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal.
Topics: Animals; Arginine; Cattle; Chromatography, High Pressure Liquid; Crystallins; Diabetes Mellitus, Experimental; Dimerization; Erythrocytes; Glutathione; Glycation End Products, Advanced; Lactoylglutathione Lyase; Lysine; Magnetic Resonance Spectroscopy; Maillard Reaction; Models, Chemical; Oxidative Stress; Pyridoxamine; Pyruvaldehyde; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances | 2002 |
Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells.
Topics: Animals; Apoptosis; Arginine; Azoles; beta-Galactosidase; Cells, Cultured; Cellular Senescence; Collagen Type I; Diabetes Mellitus, Experimental; Endothelium, Vascular; Free Radical Scavengers; Glycosylation; Humans; Isoindoles; Kinetics; Metalloporphyrins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Organoselenium Compounds; Peroxynitrous Acid; Phenotype; Rats; Rats, Zucker | 2002 |
L-arginine reduces structural remodeling in the diabetic rat myocardium.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Male; Myocardium; Nitric Oxide Synthase; Rats; Rats, Wistar; Ventricular Remodeling | 2002 |
Streptozotocin diabetes: a glucoreceptor dysfunction affecting D cells as well as B and A cells.
Topics: Animals; Arginine; Calcium; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glucose; Insulin; Isoproterenol; Male; Pancreas; Somatostatin | 1979 |
Increased somatostatin release from pancreases of alloxan diabetic rats perfused in vitro.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; In Vitro Techniques; Insulin; Male; Pancreas; Rats; Somatostatin | 1979 |
Response of extrapancreatic glucagon to arginine in dogs.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Gastrectomy; Glucagon; Insulin; Pancreatectomy | 1979 |
Plasma glucagon responses to insulin-induced hypoglycaemia and arginine in normal and alloxan diabetic rats.
Topics: Alloxan; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Hypoglycemia; Insulin; Male; Rats | 1979 |
Effect of insulin treatment upon response of extrapancreatic glucagon to arginine.
Topics: Alloxan; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Immunoassay; Insulin; Pancreas; Pancreatectomy; Time Factors | 1979 |
Somatotrophic diabetes: insulin release responses to arginine and glucagon in dogs.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Food; Glucagon; Glucose; Growth Hormone; Insulin; Male; Pancreas | 1978 |
Effect of free fatty acids and amino acids on glucagon and insulin secretions in normal and diabetic ducks.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Ducks; Glucagon; Insulin; Male; Oleic Acids; Pancreatectomy | 1978 |
The effect of potassium and valinomycin on insulin and glucagon secretion in the perfused rat pancreas.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Ethanol; Glucagon; Insulin; Insulin Secretion; Kinetics; Pancreas; Perfusion; Potassium; Rats; Valinomycin | 1978 |
Demonstration of gastric glucagon hypersecretion in insulin-deprived alloxan-diabetic dogs.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Gastric Mucosa; Glucagon; Infusions, Parenteral; Insulin; Pancreas | 1977 |
Glucagon: role in the hyperglycemia of diabetes mellitus.
Topics: Animals; Arginine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Dogs; Glucagon; Growth Hormone-Releasing Hormone; Hyperglycemia; Insulin; Oligopeptides; Pancreatectomy | 1975 |
Heterogeneity of plasma glucagon immunoreactivity in normal, depancreatized, and alloxan-diabetic dogs.
Topics: Animals; Arginine; Chromatography, Gel; Diabetes Mellitus, Experimental; Dogs; Glucagon; Insulin; Iodine Radioisotopes; Molecular Weight; Pancreas; Pancreatectomy; Phlorhizin; Somatostatin | 1975 |
Endothelium-dependent inhibition of Na(+)-K+ ATPase activity in rabbit aorta by hyperglycemia. Possible role of endothelium-derived nitric oxide.
Topics: Animals; Aorta; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hyperglycemia; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Osmolar Concentration; Rabbits; Rubidium Radioisotopes; Sodium-Potassium-Exchanging ATPase | 1992 |
Altered microvascular reactivity to endothelin-1, endothelin-3 and NG-nitro-L-arginine methyl ester in streptozotocin-induced diabetes mellitus.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Endothelins; Male; Microcirculation; Nitroarginine; Rats; Rats, Inbred Strains; Vasopressins; Xenon Radioisotopes | 1992 |
Effect of diabetes mellitus on flow-mediated and endothelium-dependent dilatation of the rat basilar artery.
Topics: Acetylcholine; Animals; Arginine; Basilar Artery; Blood Flow Velocity; Blood Glucose; Diabetes Mellitus, Experimental; Dilatation, Pathologic; Endothelium, Vascular; Male; Nitroprusside; Rats; Rats, Sprague-Dawley; Vasodilation | 1992 |
Bioassay of endothelium-derived relaxing factor in diabetic rat aorta.
Topics: Acetylcholine; Animals; Aorta; Arginine; Biological Assay; Diabetes Mellitus, Experimental; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasoconstriction | 1992 |
Endothelium-dependent relaxation and noradrenaline sensitivity in mesenteric resistance arteries of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Arginine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Female; Indomethacin; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; omega-N-Methylarginine; Rats | 1992 |
L-arginine reduces glomerular basement membrane collagen N epsilon-carboxymethyllysine in the diabetic db/db mouse.
Topics: Administration, Oral; Animals; Arginine; Basement Membrane; Collagen; Diabetes Mellitus, Experimental; Glycosylation; Kidney Glomerulus; Lysine; Mice; Mice, Mutant Strains | 1992 |
Effect of L-arginine on pancreatic arginase activity and polyamines in alloxan treated rats.
Topics: Animals; Arginase; Arginine; Diabetes Mellitus, Experimental; Male; Pancreas; Polyamines; Putrescine; Rats; Spermidine; Spermine | 1992 |
Markedly reduced beta-cell function does not result in insulin resistance in islet autografted dogs.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Disease Models, Animal; Dogs; Female; Glucagon; Insulin; Insulin Resistance; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Pancreatectomy; Transplantation, Autologous | 1992 |
Increased sensitivity to endothelin-1 in isolated Krebs'-perfused kidneys of streptozotocin-diabetic rats.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arginine; Body Weight; Diabetes Mellitus, Experimental; Endothelins; In Vitro Techniques; Kidney; Male; Nitric Oxide; Nitroarginine; Norepinephrine; Organ Size; Perfusion; Rats; Rats, Inbred Strains; Vasoconstriction | 1992 |
Relative hypersecretion of amylin to insulin from rat pancreas after neonatal STZ treatment.
Topics: Amyloid; Analysis of Variance; Animals; Animals, Newborn; Arginine; Diabetes Mellitus, Experimental; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Islets of Langerhans; Kinetics; Male; Perfusion; Radioimmunoassay; Rats; Rats, Inbred Strains; Streptozocin | 1992 |
Diminished muscarinic receptor-mediated cerebral blood flow response in streptozotocin-treated rats.
Topics: Animals; Arginine; Carotid Arteries; Cerebral Cortex; Cerebrovascular Circulation; Diabetes Mellitus, Experimental; Injections, Intra-Arterial; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Oxotremorine; Oxygen Consumption; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Regulation of spontaneous EDRF release in diabetic rat aorta by oxygen free radicals.
Topics: Animals; Aorta; Arginine; Biological Assay; Diabetes Mellitus, Experimental; Free Radicals; Male; Nitric Oxide; omega-N-Methylarginine; Oxygen; Rats; Rats, Inbred Strains; Superoxide Dismutase; Vasoconstriction | 1992 |
Suppression of low dose streptozotocin induced diabetes in mice by administration of a nitric oxide synthase inhibitor.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; In Vitro Techniques; Islets of Langerhans; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Random Allocation; Rats; Rats, Inbred Strains | 1991 |
Progressive and concurrent deterioration of vagus-stimulated and hypoglycemia-induced glucagon secretion in streptozotocin-diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Electric Stimulation; Glucagon; Hypoglycemia; Insulin; Rats; Rats, Inbred Strains; Vagus Nerve | 1992 |
Mechanism of impaired responses of cerebral arterioles during diabetes mellitus.
Topics: Animals; Arginine; Arterioles; Brain; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Nitric Oxide; omega-N-Methylarginine; Prostaglandins H; Rats; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxanes; Vasoconstriction; Vasodilation | 1991 |
Inhibition of nitric oxide generation affects the induction of diabetes by streptozocin in mice.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Islets of Langerhans; Isomerism; Male; Mice; Mice, Inbred CBA; Necrosis; Nitric Oxide; omega-N-Methylarginine; Streptozocin | 1991 |
Plasma insulin and glucagon and their release from pancreatic islet in hyperosmolar diabetic rat.
Topics: Animals; Arginine; Blood Glucose; Dehydration; Diabetes Mellitus, Experimental; Glucagon; Hydrocortisone; Insulin; Islets of Langerhans; Male; Osmotic Pressure; Rats; Rats, Inbred Strains; Streptozocin | 1991 |
The effects of endothelin-1 and NG-nitro-L-arginine methyl ester on regional haemodynamics in conscious rats with streptozotocin-induced diabetes mellitus.
Topics: Animals; Arginine; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Endothelins; Heart Rate; Hemodynamics; Hindlimb; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred Strains; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Vasodilation | 1991 |
Reduction in insulitis following administration of IFN-gamma and TNF-alpha in the NOD mouse.
Topics: Animals; Arginine; Autoimmune Diseases; Blood Glucose; Diabetes Mellitus, Experimental; Drug Synergism; H-2 Antigens; Interferon-gamma; Islets of Langerhans; Mice; Mice, Mutant Strains; Pancreatitis; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1991 |
Selective impairment of hindquarters vasodilator responses to bradykinin in conscious Wistar rats with streptozotocin-induced diabetes mellitus.
Topics: Acetylcholine; Animals; Arginine; Blood Glucose; Blood Pressure; Bradykinin; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hindlimb; Male; NG-Nitroarginine Methyl Ester; Nitroglycerin; Rats; Rats, Inbred Strains; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Vasodilation | 1991 |
Beta-cell dysfunction in hyperglycaemic rat models: recovery of glucose-induced insulin secretion with lowering of the ambient glucose level.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Hyperglycemia; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Organ Size; Pancreatectomy; Perfusion; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Abnormal regulation by glucose of somatostatin secretion in the perfused pancreas of NIDDM rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin | 1990 |
Abnormal B-cell function in rats with non-insulin-dependent diabetes induced by neonatal streptozotocin: effect of in vivo insulin, phlorizin, or vanadate treatments.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Phlorhizin; Rats; Rats, Inbred Strains; Vanadates | 1991 |
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; In Vitro Techniques; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Reference Values | 1991 |
Correlations of in vivo beta-cell function tests with beta-cell mass and pancreatic insulin content in streptozocin-administered baboons.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Immunoenzyme Techniques; Insulin; Islets of Langerhans; Male; Pancreas; Papio; Prediabetic State; Reference Values | 1991 |
Hyper-response of insulin release to arginine in streptozotocin-induced diabetic rats with hepatic vagotomy.
Topics: Animals; Arginine; Chemoreceptor Cells; Diabetes Mellitus, Experimental; Female; Glucose; Insulin; Insulin Secretion; Liver; Rats; Rats, Inbred Strains; Vagus Nerve | 1990 |
Immunosuppression and pancreatic islet transplantation.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glucose Tolerance Test; Graft Rejection; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans Transplantation | 1990 |
Insulin release from the pancreas and fuel metabolism during late gestation in chemically diabetic rats.
Topics: Animals; Arginine; Body Weight; Diabetes Mellitus, Experimental; Fasting; Female; Glucose; Insulin; Insulin Secretion; Ketone Bodies; Mice; Mice, Inbred Strains; Pancreas; Pregnancy; Pregnancy in Diabetics; Streptozocin | 1990 |
Dietary treatment ameliorates overt diabetes and decreased insulin secretion to glucose, induced by overeating in impaired glucose tolerant mice.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diet; Dietary Fiber; Eating; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Male; Mice; Mice, Inbred ICR; Pancreas; Perfusion | 1990 |
The evolution of function and response to arginine challenge and pregnancy of portally and systemically placed islet cell grafts in streptozotocin diabetic mice.
Topics: Animals; Arginine; Blood Glucose; Blood Vessels; Body Weight; Diabetes Mellitus, Experimental; Female; Glucose Tolerance Test; Glycated Hemoglobin; Insulin; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Pancreas; Portal System; Pregnancy; Pregnancy, Animal | 1990 |
Abnormal insulin secretion in a streptozocin model of diabetes. Effects of insulin treatment.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1985 |
Arginine stimulated insulin and glucagon release from islets transplanted into the liver of diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Female; Glucagon; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Liver; Rats; Rats, Inbred Lew | 1989 |
Islet transplantation to the renal subcapsular space in streptozotocin-diabetic rats. Long-term effects on insulin and glucagon secretion.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Kidney; Male; Rats; Rats, Inbred Strains | 1989 |
Insulin and glucagon secretion in streptozotocin-diabetic rats: influences of islets transplanted to the renal subcapsular space.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Increased beta-cell secretory responsiveness to ceruletide and TPA in streptozocin-induced mildly diabetic rats.
Topics: Animals; Arginine; Carbachol; Ceruletide; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Streptozocin; Tetradecanoylphorbol Acetate | 1989 |
Long-term gliclazide treatment improves the in vitro glucose-induced insulin release in rats with type 2 (non-insulin-dependent) diabetes induced by neonatal streptozotocin.
Topics: Animals; Animals, Newborn; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gliclazide; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Rats, Inbred Strains; Reference Values; Streptozocin; Sulfonylurea Compounds | 1989 |
Hypersensitivity to arginine of both B and D pancreatic cells in adult streptozotocin-diabetic rats.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin | 1989 |
[Studies on glucose metabolism and pancreatic endocrine function after simultaneous major resection of the liver and pancreas].
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Female; Glucagon; Glucose; Glucose Tolerance Test; Hepatectomy; Hypertrophy; Insulin; Insulin Secretion; Islets of Langerhans; Liver; Male; Pancreatectomy; Regeneration | 1989 |
Comparison of biochemical properties of liver arginase from streptozocin-induced diabetic and control mice.
Topics: Animals; Arginase; Arginine; Binding Sites; Cytosol; Diabetes Mellitus, Experimental; Hot Temperature; Kinetics; Liver; Male; Manganese; Mice; Mice, Inbred ICR; Molecular Weight; Protein Conformation | 1989 |
Reversal of D- and A-cell insensitivity to glucose in alloxan-diabetic dogs by treatment with the artificial beta cell (Biostator).
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Glucagon; Glucose; Insulin; Insulin Infusion Systems; Islets of Langerhans; Somatostatin | 1985 |
Unresponsiveness to glucose in a streptozocin model of diabetes. Inappropriate insulin and glucagon responses to a reduction of glucose concentration.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Epinephrine; Glucagon; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin | 1985 |
Insulin and glucagon response of the diabetic Chinese hamster in the Asahikawa colony.
Topics: Animals; Arginine; Blood Glucose; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Female; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Islets of Langerhans; Male; Pancreas; Somatostatin | 1985 |
Pancreatic A- and D-cell response to arginine during acute alloxan-induced intra-islet insulinopenia.
Topics: Alloxan; Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Insulin Infusion Systems; Islets of Langerhans; Male; Rats; Rats, Inbred Strains; Somatostatin | 1988 |
[Combined administration of sodium chloro-2-propionate and insulin on the secretion of glucagon by the pancreas in the diabetic rat].
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Drug Combinations; Glucagon; Glucose; Hydrocarbons, Chlorinated; Insulin; Pancreas; Propionates; Rats; Rats, Inbred Strains | 1988 |
Dietary and hormonal regulation of aldolase B gene expression.
Topics: Adrenalectomy; Animals; Arginine; Cyclic AMP; Diabetes Mellitus, Experimental; Dietary Carbohydrates; Fructose-Bisphosphate Aldolase; Gene Expression Regulation; Glucagon; Hormones; Intestine, Small; Kidney; Liver; Male; Parathyroid Glands; Rats; Rats, Inbred Strains; RNA, Messenger; Thyroidectomy | 1985 |
Defects in beta-cell function and insulin sensitivity in normoglycemic streptozocin-treated baboons: a model of preclinical insulin-dependent diabetes.
Topics: Adult; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Fasting; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Papio | 1988 |
A comparison of portal versus systemic venous drainage in murine foetal pancreatic islet transplantation.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Female; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Kidney; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Portal Vein; Spleen | 1986 |
Insulin treatment improves glucose-induced insulin release in rats with NIDDM induced by streptozocin.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Insulin; Insulin Secretion; Rats; Rats, Inbred Strains; Time Factors | 1987 |
Abnormal calcium handling by perifused pancreatic islets from neonatal streptozotocin diabetic model rats.
Topics: Animals; Animals, Newborn; Arginine; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Insulin; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains | 1987 |
Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rats.
Topics: Animals; Arginine; Blood Glucose; Body Weight; Chronic Disease; Diabetes Mellitus, Experimental; Glycosuria; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Pancreatectomy; Phlorhizin; Rats; Rats, Inbred Strains | 1987 |
Defect of the first-phase insulin secretion to glucose stimulation in the perfused pancreas of the nonobese diabetic (NOD) mouse.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred ICR; Mice, Mutant Strains | 1986 |
Selective impairment of pancreatic A cell suppression by glucose during acute alloxan-induced insulinopenia: in vitro study on isolated perfused rat pancreas.
Topics: Alloxan; Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains | 1986 |
Evidence for normal in vitro Ca2+-stimulated insulin release in rats with non-insulin-dependent diabetes.
Topics: Animals; Arginine; Calcium; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Inbred Strains | 1986 |
Loss of insulin response to glucose but not arginine during the development of autoimmune diabetes in BB/W rats: relationships to islet volume and glucose transport rate.
Topics: Age Factors; Animals; Arginine; Autoimmune Diseases; Biological Transport; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Rats; Rats, Inbred Strains; Secretory Rate | 1986 |
Dynamics of glucose-induced insulin release during the spontaneous remission of streptozocin diabetes induced in the newborn rat.
Topics: Animals; Animals, Newborn; Arginine; Diabetes Mellitus, Experimental; Glucose; Insulin; Pancreas; Perfusion; Rats; Rats, Inbred Strains | 1985 |
Pancreatic islet allograft function in nonimmunosuppressed conscious mice.
Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Immunosuppression Therapy; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Theophylline | 1985 |
Effect of sodium 2-chloropropionate on glucagon secretion in the rat.
Topics: Alanine; Animals; Arginine; Diabetes Mellitus, Experimental; Glucagon; Glycosuria; Hydrocarbons, Chlorinated; Male; Pancreas; Perfusion; Propionates; Rats; Rats, Inbred Strains | 1985 |