arginine has been researched along with Allodynia in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 23 (29.87) | 18.2507 |
| 2000's | 21 (27.27) | 29.6817 |
| 2010's | 27 (35.06) | 24.3611 |
| 2020's | 6 (7.79) | 2.80 |
| Authors | Studies |
|---|---|
| Castro Perez, A; Gama Duarte, ID; Lima Romero, TR; Teixeira, LRM | 1 |
| Hall, C; Roman, K; Schaeffer, AJ; Thumbikat, P | 1 |
| Balabanyan, VY; Kashkin, VA; Makarov, VG; Makarova, MN; Muzhikyan, AА; Shekunova, EV | 1 |
| Ando, M; Asano, S; Hayashi, Y; Iinuma, T; Iwata, K; Kanno, K; Kimura, Y; Koyama, R; Kubo, A; Lee, J; Ohara, K; Sakanashi, K; Shinoda, M; Soma, K; Sugawara, S | 1 |
| Ahmadi-Zeidabadi, M; Jeddi, S; Kohlmeier, KA; Mohammadi, F; Shabani, M | 1 |
| Ahmadimoghaddam, D; Izadidastenaei, Z; Mohammadi, S; Salehi, I; Zarei, M | 1 |
| Courteix, C; Davin, N; Eschalier, A; Farges, MC; Privat, AM; Rondón, LJ; Sion, B; Vasson, MP | 1 |
| Chen, SR; Jin, XG; Pan, HL | 1 |
| Lotfipour, S; Smith, MT | 1 |
| Doolen, S; Fu, W; Gutierrez, JJP; K Taylor, B; Nelson, TS; Santos, DF; Ye, N; Zhou, J | 1 |
| Chen, W; Fu, W; Marvizon, JC; Taylor, BK | 1 |
| Akhtar, MN; Akira, A; Israf, DA; Kamaldin, MN; Lajis, N; Ming-Tatt, L; Mohamad, AS; Perimal, EK; Sulaiman, MR | 1 |
| Echizenya, S; Honda, K; Ito, R; Iwata, K; Kaji, K; Lee, J; Ohara, K; Shinoda, M; Sugiyama, T; Takahashi, O; Urata, K; Watase, T | 1 |
| Cortes, S; Costa, A; Duarte, I; Galdino, G; Romero, T; Santos, R; Silva, G | 1 |
| Abareghi, F; Nazeri, M; Razavinasab, M; Shabani, M | 1 |
| Prostran, MS; Savic Vujovic, KR; Srebro, DP; Vucković, SM | 1 |
| Bertin, I; Bihel, F; Bourguignon, JJ; Humbert, JP; Laboureyras, E; Mollereau, C; Petit-Demoulière, B; Schmitt, M; Schneider, E; Schneider, S; Simonin, F; Simonnet, G; Wagner, P | 1 |
| de Carvalho Veloso, C; de Castro Perez, A; Duarte, ID; Duarte, LP; Ferreira, RC; Klein, A; Rodrigues, VG; Romero, TR | 1 |
| Acuña, MA; Benke, D; Ralvenius, WT; Rudolph, U; Zeilhofer, HU | 1 |
| Bahr, MH; Hamza, M; Masoud, SI; Saad, SS | 1 |
| Abd-Alkhalek, HA; El-Bakly, WM; El-Lithy, GM; Hamza, M; Masoud, SI; Matboli, M | 1 |
| Kuphal, KE; Pedrazzini, T; Solway, B; Taylor, BK | 1 |
| Crestani, F; Knabl, J; Rudolph, U; Zeilhofer, HU; Zeilhofer, UB | 1 |
| Duarte, ID; Romero, TR | 1 |
| Chereshnev, I; Criesta, M; Kolesnikov, YA; Pan, YX; Pasternak, GW | 1 |
| Dandekar, MP; Kokare, DM; Singru, PS; Subhedar, NK; Upadhya, MA | 1 |
| Ikeda, T; Matsushima, O; Naono, R; Nishimori, T; Sakoda, S; Sunakawa, N | 1 |
| Kostić, S; Puljak, L; Sapunar, D; Vukojević, K | 1 |
| Ahn, JH; Choe, MA; Han, JA; Kim, JI; Kim, KH | 1 |
| Côrtes, SF; Duarte, ID; Galdino, GS; Perez, AC; Resende, LC; Romero, TR; Silva, GC | 2 |
| Duarte, ID; Resende, LC; Romero, TR | 1 |
| Gupta, A; Kalonia, H; Kumar, A; Kumar, P; Meena, S | 1 |
| Choi, JI; Kim, WM; Kim, YO; Lee, HG; Yoon, MH | 1 |
| Barbosa, AL; Moraes, MO; Oliveira, GJ; Pinheiro, CA; Ribeiro, RA; Souza, MH; Torres, JN; Vale, ML | 1 |
| Alves, DP; da Motta, PG; Duarte, ID; Klein, A; Romero, TR | 1 |
| Cidral-Filho, FJ; Martins, DF; Mazzardo-Martins, L; Santos, AR; Stramosk, J | 1 |
| Amarante, LH; Duarte, ID | 1 |
| Carvajal, C; Dumont, Y; Gardell, L; Lai, J; Ossipov, MH; Porreca, F; Quirion, R; Zhang, ET | 1 |
| Ferreira, SH; Parada, CA; Vivancos, GG | 1 |
| Maegawa, FA; Tonussi, CR | 1 |
| Zhang, XC; Zhang, YQ; Zhao, ZQ | 1 |
| Dokmeci, D; Guray, G; Ozyigit, F; Sapolyo, N; Tamer, M; Ulugol, A | 1 |
| Castro, MS; Duarte, ID; Francischi, JN; Pacheco, DF; Perez, AC; Reis, GM | 1 |
| Calixto, JB; Kassuya, CA; Luiz, AP; Meotti, FC; Pizzolatti, MG; Santos, AR | 1 |
| Dudhgaonkar, SP; Kumar, D; Naik, AK; Tandan, SK | 1 |
| Kamei, J; Nozaki, C; Saitoh, A | 1 |
| Eneroth, A; Kristensson, K; Olsson, T; Wiesenfeld-Hallin, Z | 1 |
| Björkman, R; Hallman, KM; Hedner, J; Hedner, T; Henning, M | 1 |
| Gebhart, GF; Meller, ST | 1 |
| Coderre, TJ; Yashpal, K | 1 |
| Mashimoto, T; Ohara, A; Shibuta, S; Yoshiya, I; Zhang, P | 1 |
| Babbedge, R; Dray, A; Levers, T; Thompson, SW; Urban, L | 1 |
| Devissaguet, M; Ferreira, SH; Lesieur, D; Lorenzetti, BB; Tsouderos, Y | 1 |
| Furness, LE; Maier, SF; Watkins, LR; Wiertelak, EP | 1 |
| Ferreira, SH; Tonussi, CR | 1 |
| Furness, LE; Horan, R; Maier, SF; Martinez, J; Watkins, LR; Wiertelak, EP | 1 |
| Cummings, CP; Gebhart, GF; Meller, ST; Traub, RJ | 1 |
| Ferreira, SH | 1 |
| Henry, JL; Hui-Chan, CW; Radhakrishnan, V; Yashpal, K | 1 |
| Iwatsubo, K; Kawabata, A; Takagi, H; Takaya, S | 1 |
| Goettl, VM; Larson, AA | 1 |
| Iwase, K; Seo, HG; Shigenaga, Y; Takemura, M; Taniguchi, N; Yonehara, N; Yoshimura, M | 1 |
| Asano, T; Dohi, S; Masue, T; Shimonaka, H | 1 |
| Sugimoto, Y; Yamada, J; Yoshikawa, T | 1 |
| Calixto, JB; Ferreira, J; Santos, AR | 1 |
| Cury, Y; Giorgi, R; Picolo, G | 1 |
| Duarte, ID; Ferreira, SH | 1 |
| Abarca, C; Contreras, E; Oliva, P; Sepúlveda, MJ; Silva, E | 1 |
| Ichikawa, A; Ito, S; Kobayashi, T; Minami, T; Nakano, H; Narumiya, S; Sugimoto, Y; Ushikubi, F | 1 |
| Jain, NK; Kulkarni, SK; Patil, CS; Singh, A | 1 |
| Taiwo, OB; Taylor, BK | 1 |
| Haley, JE; Kitto, KF; Wilcox, GL | 1 |
| Fukushima, Y; Fukuzumi, Y; Kawabata, A; Takagi, H | 1 |
| Gebhart, GF; Maves, TJ; Meller, ST; Pechman, PS | 1 |
| Kawabata, A; Nishimura, Y; Takagi, H | 1 |
| Sun, J; Yan, J; Zeng, Z | 1 |
1 review(s) available for arginine and Allodynia
| Article | Year |
|---|---|
Inflammatory pain: the role of cytokines and its control by drugs which release nitric oxide.
Topics: Analgesics; Arginine; Cyclic GMP; Cyclooxygenase Inhibitors; Cytokines; Down-Regulation; Humans; Hyperalgesia; Inflammation; Nitric Oxide; Nociceptors; Sympatholytics | 1993 |
76 other study(ies) available for arginine and Allodynia
| Article | Year |
|---|---|
Magnesium sulphate activates the L-arginine/NO/cGMP pathway to induce peripheral antinociception in mice
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dinoprostone; Hyperalgesia; Magnesium Sulfate; Male; Mice; Nitric Oxide; Nitroarginine; Phosphodiesterase Inhibitors; Soluble Guanylyl Cyclase | 2022 |
TRPV1 in experimental autoimmune prostatitis.
Topics: Animals; Arginine; Autoimmune Diseases; Extracellular Signal-Regulated MAP Kinases; Ganglia, Spinal; Hyperalgesia; Male; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Pelvic Pain; Phosphorylation; Prostatitis; Spinal Cord; TRPV Cation Channels | 2020 |
Therapeutic efficacy of arginine-rich exenatide on diabetic neuropathy in rats.
Topics: Animals; Arginine; Blood Glucose; Diabetic Neuropathies; Dose-Response Relationship, Drug; Exenatide; Gene Expression Regulation; Glycated Hemoglobin; Hyperalgesia; Insulin; Islets of Langerhans; Locomotion; Male; Organ Size; Rats; Rats, Wistar; Sciatic Nerve | 2020 |
Involvement of Satellite Cell Activation via Nitric Oxide Signaling in Ectopic Orofacial Hypersensitivity.
Topics: Animals; Arginine; Disease Models, Animal; Glial Fibrillary Acidic Protein; Humans; Hyperalgesia; Mandibular Nerve; Mandibular Nerve Injuries; Neuralgia; Neuroglia; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Satellite Cells, Skeletal Muscle; Signal Transduction; Trigeminal Ganglion; Trigeminal Nerve Injuries | 2020 |
Affective dimensions of pain and region -specific involvement of nitric oxide in the development of empathic hyperalgesia.
Topics: Animals; Arginine; Brain; Disease Models, Animal; Empathy; Female; Hyperalgesia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociception; Pain; Rats, Wistar | 2020 |
Bupleurum falcatum L. alleviates nociceptive and neuropathic pain: Potential mechanisms of action.
Topics: Animals; Arginine; Bupleurum; Cyclic GMP; Formaldehyde; Hyperalgesia; Iran; Male; Medicine, Traditional; Mice; Nitric Oxide; Oils, Volatile; Pain; Phytotherapy; Plant Oils; Plant Roots; Potassium Channels; Spinal Cord Injuries | 2021 |
L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration.
Topics: Administration, Oral; Agmatine; Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Neuralgia; Nitric Oxide; Rats; Rats, Sprague-Dawley; Streptozocin | 2018 |
Endogenous nitric oxide inhibits spinal NMDA receptor activity and pain hypersensitivity induced by nerve injury.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Central Nervous System Agents; Cyclic GMP; Disease Models, Animal; Ethylmaleimide; Excitatory Amino Acid Antagonists; Hot Temperature; Hyperalgesia; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type I; Posterior Horn Cells; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; Soluble Guanylyl Cyclase; Spinal Nerves; Tissue Culture Techniques; Touch | 2017 |
Morphine hyposensitivity in streptozotocin-diabetic rats: Reversal by dietary l-arginine treatment.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diet; Hyperalgesia; Morphine; Nitric Oxide; Rats | 2018 |
An NPY Y1 receptor antagonist unmasks latent sensitization and reveals the contribution of protein kinase A and Epac to chronic inflammatory pain.
Topics: Animals; Arginine; Chronic Pain; Cyclic AMP-Dependent Protein Kinases; Guanine Nucleotide Exchange Factors; Hyperalgesia; Inflammation; Male; Mice; Pain Measurement; Pain Threshold; Phosphorylation; Receptors, Neuropeptide Y | 2019 |
Neuropeptide Y release in the rat spinal cord measured with Y1 receptor internalization is increased after nerve injury.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arginine; Calcium Channel Blockers; Capsaicin; Cyclic AMP-Dependent Protein Kinases; Excitatory Amino Acid Antagonists; Hyperalgesia; Indoles; Interneurons; Lidocaine; Male; Microscopy, Confocal; Neuropeptide Y; Nociception; omega-Conotoxins; Peripheral Nerve Injuries; Posterior Horn Cells; Potassium Chloride; Protein Transport; Protein Tyrosine Phosphatases; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neuropeptide Y; Sensory System Agents; Spinal Cord; Spinal Nerve Roots; TRPV Cation Channels; Voltage-Gated Sodium Channel Blockers | 2019 |
Peripheral antinociception of a chalcone, flavokawin B and possible involvement of the nitric oxide/cyclic guanosine monophosphate/potassium channels pathway.
Topics: Analgesics; Animals; Arginine; Carrageenan; Chalcone; Cyclic GMP; Disease Models, Animal; Flavonoids; Hyperalgesia; Male; Nitric Oxide; Potassium Channel Blockers; Potassium Channels; Rats; Signal Transduction | 2013 |
Nitric oxide signaling contributes to ectopic orofacial neuropathic pain.
Topics: Animals; Arginine; Enzyme Inhibitors; Enzyme Precursors; Facial Pain; Hyperalgesia; Indazoles; Lip; Male; Mandibular Nerve; Neural Pathways; Neuralgia; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Threshold; Rats; Rats, Sprague-Dawley; Sensory Thresholds; Signal Transduction; Touch; Trigeminal Ganglion; Trigeminal Nerve Injuries | 2013 |
Ang-(1-7) activates the NO/cGMP and ATP-sensitive K+ channels pathway to induce peripheral antinociception in rats.
Topics: Adenosine Triphosphate; Analgesics; Angiotensin I; Animals; Arginine; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; KATP Channels; Male; Nitric Oxide; Pain; Pain Measurement; Peptide Fragments; Rats; Rats, Wistar | 2014 |
Role of nitric oxide in altered nociception and memory following chronic stress.
Topics: Animals; Anxiety; Arginine; Avoidance Learning; Chronic Disease; Electroshock; Enzyme Inhibitors; Exploratory Behavior; Hot Temperature; Hyperalgesia; Learning Disabilities; Male; Memory; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nociception; Rats, Sprague-Dawley; Stress, Psychological; Swimming | 2014 |
Nitric oxide synthase modulates the antihyperalgesic effect of the NMDA receptor antagonist MK-801 on Carrageenan-induced inflammatory pain in rats.
Topics: Animals; Arginine; Carrageenan; Dizocilpine Maleate; Hyperalgesia; Inflammation; Isothiuronium; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain; Pain Threshold; Rats, Wistar; Receptors, N-Methyl-D-Aspartate | 2014 |
Development of a peptidomimetic antagonist of neuropeptide FF receptors for the prevention of opioid-induced hyperalgesia.
Topics: Analgesics, Opioid; Animals; Arginine; Chemical Phenomena; Cyclic AMP; Fentanyl; HEK293 Cells; Humans; Hyperalgesia; Male; Microsomes, Liver; Ornithine; Pain Threshold; Peptidomimetics; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide; Structure-Activity Relationship; Time Factors; Tritium | 2015 |
Tingenone, a pentacyclic triterpene, induces peripheral antinociception due to NO/cGMP and ATP-sensitive K(+) channels pathway activation in mice.
Topics: Analgesics; Animals; Arginine; Cyclic GMP; Dinoprostone; Hyperalgesia; KATP Channels; Male; Maytenus; Mice; Nitric Oxide; Plant Roots; Signal Transduction; Triterpenes | 2015 |
Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype.
Topics: Analgesia; Animals; Arginine; Benzodiazepines; Diazepam; GABA Modulators; Gene Expression; Histidine; Hyperalgesia; Hypnotics and Sedatives; Male; Mice; Midazolam; Pain; Pain Management; Point Mutation; Receptors, GABA-A; Spinal Cord | 2015 |
Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Animals; Arginine; Hindlimb; Hyperalgesia; Ibuprofen; Male; Mice; Nitric Oxide; Pain, Postoperative; Physical Stimulation; Receptors, Adrenergic, alpha-2; Spinal Cord; Touch; Yohimbine | 2016 |
Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy.
Topics: Animals; Arginine; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Drug Therapy, Combination; Female; Hyperalgesia; Ibuprofen; MicroRNAs; Muscles; Nitric Oxide; Peripheral Nervous System Diseases; Rats, Wistar; Skin; Spinal Cord; Streptozocin; Up-Regulation | 2016 |
Y1 receptor knockout increases nociception and prevents the anti-allodynic actions of NPY.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arginine; Behavior, Animal; Disease Models, Animal; Hot Temperature; Hyperalgesia; Inflammation; Male; Mice; Mice, Knockout; Neuropeptide Y; Pain; Pain Measurement; Receptors, Neuropeptide Y; Sciatic Neuropathy | 2008 |
Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice.
Topics: Analysis of Variance; Anesthetics; Animals; Arginine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Histidine; Hyperalgesia; Indoles; Male; Mice; Mice, Mutant Strains; Motor Activity; Physical Stimulation; Point Mutation; Protein Subunits; Pyrroles; Receptors, GABA-A | 2009 |
alpha(2)-Adrenoceptor agonist xylazine induces peripheral antinociceptive effect by activation of the L-arginine/nitric oxide/cyclic GMP pathway in rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guanylate Cyclase; Hyperalgesia; Male; Nitric Oxide; Nitric Oxide Synthase; Phosphoric Diester Hydrolases; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Xylazine | 2009 |
Opposing actions of neuronal nitric oxide synthase isoforms in formalin-induced pain in mice.
Topics: Analysis of Variance; Animals; Arginine; Drug Tolerance; Formaldehyde; Hyperalgesia; Injections, Spinal; Isoenzymes; Male; Mice; Morphine; Nitric Oxide Synthase Type I; Nitroarginine; Oligodeoxyribonucleotides, Antisense; Pain; Pain Measurement; Pain Threshold | 2009 |
Involvement of neuropeptide Y in the acute, chronic and withdrawal responses of morphine in nociception in neuropathic rats: behavioral and neuroanatomical correlates.
Topics: Analgesics, Opioid; Animals; Arginine; Behavior, Animal; Drug Tolerance; Hyperalgesia; Male; Morphine; Neuropeptide Y; Pain Measurement; Peripheral Nervous System Diseases; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Sciatic Nerve; Substance Withdrawal Syndrome | 2009 |
The amino-terminal region of hemokinin-1 regulates the induction of thermal hyperalgesia in rats.
Topics: Amino Acid Sequence; Animals; Arginine; Hyperalgesia; Male; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Serine; Substance P; Tachykinins; Threonine | 2010 |
Attenuation of pain-related behavior evoked by injury through blockade of neuropeptide Y Y2 receptor.
Topics: Analysis of Variance; Animals; Arginine; Benzazepines; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Glial Fibrillary Acidic Protein; Hyperalgesia; Male; Motor Activity; Neuralgia; Neurons; Neuropeptide Y; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Rotarod Performance Test; Spinal Cord | 2011 |
Upregulation of neuronal nitric oxide synthase in the periphery promotes pain hypersensitivity after peripheral nerve injury.
Topics: Animals; Arginine; Hyperalgesia; Male; Molsidomine; Neuralgia; Nitric Oxide Synthase Type I; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Schwann Cells; Sensory Receptor Cells; Up-Regulation | 2011 |
Ketamine activates the L-arginine/Nitric oxide/cyclic guanosine monophosphate pathway to induce peripheral antinociception in rats.
Topics: Analgesia; Anesthetics, Dissociative; Animals; Arginine; Cyclic AMP; Dinoprostone; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Guanylate Cyclase; Hyperalgesia; Ketamine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Pain; Peripheral Nervous System Diseases; Quinoxalines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2011 |
The neuronal NO synthase participation in the peripheral antinociception mechanism induced by several analgesic drugs.
Topics: Acetylcholine; Analgesics; Animals; Arachidonic Acids; Arginine; Dinoprostone; Endocannabinoids; Enzyme Inhibitors; Hyperalgesia; Isoenzymes; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Pain Measurement; Peripheral Nervous System Diseases; Polyunsaturated Alkamides; Rats; Rats, Wistar | 2011 |
Effect of nitric oxide in protective effect of melatonin against chronic constriction sciatic nerve injury induced neuropathic pain in rats.
Topics: Animals; Antioxidants; Arginine; Catalase; Chronic Disease; Disease Models, Animal; Glutathione; Hyperalgesia; Lipid Peroxidation; Male; Melatonin; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Sciatic Nerve | 2011 |
Role of neuronal nitric oxide synthase in the antiallodynic effects of intrathecal EGCG in a neuropathic pain rat model.
Topics: Animals; Arginine; Catechin; Disease Models, Animal; Extremities; Hyperalgesia; Injections, Spinal; Ligation; Male; Neuralgia; Nitric Oxide; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves | 2012 |
Involvement of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in peripheral antinociception induced by N-palmitoyl-ethanolamine in rats.
Topics: Amides; Analgesics; Animals; Arginine; Cyclic GMP; Disease Models, Animal; Endocannabinoids; Ethanolamines; Hyperalgesia; Male; Neural Inhibition; Neural Pathways; Nitric Oxide; Nociception; Palmitic Acids; Rats; Rats, Wistar | 2012 |
Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in rats.
Topics: Analgesics; Animals; Arginine; Carcinoma 256, Walker; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; KATP Channels; Male; Nitric Oxide; Nociception; Oxadiazoles; Pain Measurement; Pain Threshold; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2012 |
NO/cGMP production is important for the endogenous peripheral control of hyperalgesia during inflammation.
Topics: Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Inflammation; Male; Nitric Oxide; Pain; Pain Measurement; Pressure; Rats; Rats, Wistar | 2013 |
Glycogen synthase kinase 3-specific inhibitor AR-A014418 decreases neuropathic pain in mice: evidence for the mechanisms of action.
Topics: Analgesics; Animals; Arginine; Cytokines; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Hyperalgesia; Ligation; Male; Mice; Motor Activity; Neuralgia; Nitric Oxide; Pain Measurement; Parasympathetic Nervous System; Sciatic Neuropathy; Serotonin; Spinal Cord; Thiazoles; Urea | 2012 |
The kappa-opioid agonist (+/-)-bremazocine elicits peripheral antinociception by activation of the L-arginine/nitric oxide/cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Benzomorphans; Cyclic GMP; Guanylate Cyclase; Hyperalgesia; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pain; Phosphodiesterase Inhibitors; Purinones; Rats; Rats, Wistar; Receptors, Opioid, kappa | 2002 |
Selective mediation of nerve injury-induced tactile hypersensitivity by neuropeptide Y.
Topics: Animals; Arginine; Benzazepines; Disease Models, Animal; Disease Progression; Ganglia, Spinal; Hyperalgesia; Immune Sera; Ligation; Lumbosacral Region; Male; Medulla Oblongata; Microinjections; Nerve Crush; Neuropeptide Y; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Rhizotomy; Spinal Cord; Spinal Nerves | 2002 |
Opposite nociceptive effects of the arginine/NO/cGMP pathway stimulation in dermal and subcutaneous tissues.
Topics: Animals; Arginine; Bucladesine; Cyclic GMP; Dermis; Dinoprostone; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Subcutaneous; Male; Molsidomine; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Oxadiazoles; Pain Measurement; Quinoxalines; Rats; Rats, Wistar; Subcutaneous Tissue; Time Factors | 2003 |
The L-arginine/nitric oxide/cyclic-GMP pathway apparently mediates the peripheral antihyperalgesic action of fentanyl in rats.
Topics: Analgesics, Opioid; Animals; Arginine; Cyclic GMP; Dinoprostone; Dose-Response Relationship, Drug; Fentanyl; Formaldehyde; Hyperalgesia; Male; Nitric Oxide; Nitric Oxide Synthase; Oxytocics; Rats; Rats, Wistar | 2003 |
Involvement of nitric oxide in long-term potentiation of spinal nociceptive responses in rats.
Topics: Analysis of Variance; Animals; Arginine; Drug Interactions; Enzyme Inhibitors; Evoked Potentials; Functional Laterality; Hemoglobins; Hyperalgesia; Long-Term Potentiation; Male; Nerve Fibers, Unmyelinated; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nociceptors; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatic Nerve; Spinal Cord; Time Factors | 2005 |
Antihyperalgesic, but not antiallodynic, effect of melatonin in nerve-injured neuropathic mice: Possible involvements of the L-arginine-NO pathway and opioid system.
Topics: Analgesics; Animals; Arginine; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Melatonin; Mice; Mice, Inbred Strains; Naloxone; Narcotic Antagonists; Nitric Oxide; Receptors, Opioid; Sciatic Nerve; Sciatic Neuropathy | 2006 |
delta-Opioid receptor agonist SNC80 elicits peripheral antinociception via delta(1) and delta(2) receptors and activation of the l-arginine/nitric oxide/cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Benzamides; Benzylidene Compounds; Cyclic GMP; Dinoprostone; Enzyme Inhibitors; Hyperalgesia; Male; Naltrexone; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Piperazines; Rats; Receptors, Opioid, delta | 2005 |
Analysis of the antinociceptive effect of the flavonoid myricitrin: evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways.
Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Arginine; Blotting, Western; Female; Flavonoids; Hyperalgesia; Injections, Intraperitoneal; Male; Mice; Motor Activity; Nitric Oxide; Pain; Pain Measurement; Protein Kinase C; Rats; Rats, Wistar | 2006 |
Nitric oxide and its modulators in chronic constriction injury-induced neuropathic pain in rats.
Topics: Animals; Arginine; Behavior, Animal; Cold Temperature; Constriction, Pathologic; Disease Models, Animal; Hindlimb; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Male; Neuralgia; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitrites; Nitroprusside; Pain Threshold; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sciatic Nerve; Stress, Mechanical | 2006 |
Effect of mexiletine on vincristine-induced painful neuropathy in mice.
Topics: Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Mexiletine; Mice; Mice, Inbred ICR; Neuralgia; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Pain Measurement; Pyrethrins; Vincristine | 2006 |
A new approach for the pathogenesis of human African trypanosomiasis.
Topics: Animals; Arginine; Brain; CD8-Positive T-Lymphocytes; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Sensory; Ganglia, Spinal; Growth Substances; Hot Temperature; Humans; Hyperalgesia; Injections, Spinal; Interferon-gamma; Mice; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nociceptors; Rats; Trypanosoma brucei brucei; Trypanosomiasis, African | 1994 |
Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance P.
Topics: Acetaminophen; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arginine; Behavior, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; N-Methylaspartate; Nociceptors; Rats; Rats, Sprague-Dawley; Spinal Cord Diseases; Substance P | 1994 |
Spinal mediators of hyperalgesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arginine; Calcium; Cycloleucine; Disease Models, Animal; Excitatory Amino Acids; Hot Temperature; Hyperalgesia; Male; N-Methylaspartate; Neuronal Plasticity; Neurons, Afferent; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Stress, Mechanical | 1994 |
Intracellular messengers contributing to persistent nociception and hyperalgesia induced by L-glutamate and substance P in the rat formalin pain model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arachidonic Acid; Arginine; Dexamethasone; Formaldehyde; Glutamic Acid; Hyperalgesia; Injections, Spinal; Isoquinolines; Male; Neurotransmitter Agents; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain; Pain Measurement; Pain Threshold; Piperazines; Protein Kinase C; Rats; Reflex; Substance P | 1994 |
Intracerebroventricular administration of a nitric oxide-releasing compound, NOC-18, produces thermal hyperalgesia in rats.
Topics: Animals; Arginine; Body Temperature; Brain; Hyperalgesia; Injections, Intraventricular; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroso Compounds; Nociceptors; Rats; Rats, Sprague-Dawley | 1995 |
No evidence for contribution of nitric oxide to spinal reflex activity in the rat spinal cord in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Electric Stimulation; Hyperalgesia; In Vitro Techniques; N-Methylaspartate; Nerve Fibers; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Reflex; Spinal Cord; Spinal Nerve Roots | 1995 |
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hyperalgesia; Indomethacin; Male; Methylene Blue; Nitric Oxide; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar; Thiazoles; Yohimbine | 1995 |
Illness-induced hyperalgesia is mediated by a spinal NMDA-nitric oxide cascade.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Aspirin; Binding, Competitive; Disease; Dizocilpine Maleate; Hyperalgesia; Injections, Spinal; Lipopolysaccharides; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1994 |
Mechanism of diclofenac analgesia: direct blockade of inflammatory sensitization.
Topics: Analgesia; Animals; Arginine; Carrageenan; Diclofenac; Dinoprostone; Drug Interactions; Enzyme Activation; Guanylate Cyclase; Hyperalgesia; Indomethacin; Inflammation; Injections, Intra-Articular; Knee Injuries; Male; Methylene Blue; Nitric Oxide; Nociceptors; omega-N-Methylarginine; Pain Measurement; Rats; Rats, Wistar | 1994 |
Subcutaneous formalin produces centrifugal hyperalgesia at a non-injected site via the NMDA-nitric oxide cascade.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Cordotomy; Formaldehyde; Hot Temperature; Hyperalgesia; Injections, Spinal; Injections, Subcutaneous; N-Methylaspartate; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1994 |
The role of nitric oxide in the development and maintenance of the hyperalgesia produced by intraplantar injection of carrageenan in the rat.
Topics: Animals; Arginine; Carrageenan; Edema; Hyperalgesia; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Spinal Cord; Stereoisomerism; Time Factors | 1994 |
Implication of a nitric oxide synthase mechanism in the action of substance P: L-NAME blocks thermal hyperalgesia induced by endogenous and exogenous substance P in the rat.
Topics: Animals; Arginine; Enzyme Inhibitors; Hyperalgesia; Injections, Spinal; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Neurokinin-1; Stereoisomerism; Substance P | 1995 |
Central antinociceptive effect of L-ornithine, a metabolite of L-arginine, in rats and mice.
Topics: Analgesia; Animals; Arginine; Carrageenan; Citrulline; Dipeptides; Dose-Response Relationship, Drug; Excipients; Hyperalgesia; Injections, Intraventricular; Leucine; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Ornithine; Pain Measurement; Protease Inhibitors; Rats | 1996 |
Nitric oxide mediates long-term hyperalgesic and antinociceptive effects of the N-terminus of substance P in the formalin assay in mice.
Topics: Analgesics; Animals; Arginine; Enzyme Inhibitors; Formaldehyde; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Mice; Mice, Inbred Strains; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain Measurement; Peptide Fragments; Stereoisomerism; Substance P; Time Factors | 1996 |
Nitric oxide in the rat spinal cord in Freund's adjuvant-induced hyperalgesia.
Topics: Animals; Arginine; Enzyme Inhibitors; Freund's Adjuvant; Hindlimb; Hot Temperature; Hyperalgesia; Immunohistochemistry; Injections, Intravenous; Injections, Subcutaneous; Male; NADPH Dehydrogenase; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Spinal Cord | 1997 |
Spinal antinociceptive effect of epidural nonsteroidal antiinflammatory drugs on nitric oxide-induced hyperalgesia in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Epidural Space; Hyperalgesia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Rats; Rats, Sprague-Dawley; Spinal Cord | 1999 |
A neuronal nitric oxide synthase inhibitor 7-nitroindazole reduces the 5-HT1A receptor against 8-OH-DPAT-elicited hyperphagia in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arginine; Autoreceptors; Enzyme Inhibitors; Feeding Behavior; Hyperalgesia; Hypothalamus; Indazoles; Male; Neurons; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists | 1999 |
The role of systemic, spinal and supraspinal L-arginine-nitric oxide-cGMP pathway in thermal hyperalgesia caused by intrathecal injection of glutamate in mice.
Topics: Analysis of Variance; Animals; Arginine; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Hot Temperature; Hyperalgesia; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Spinal; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine | 1999 |
delta-opioid receptors and nitric oxide mediate the analgesic effect of Crotalus durissus terrificus snake venom.
Topics: Analgesics, Non-Narcotic; Animals; Arginine; Carrageenan; Crotalid Venoms; Cyclic GMP; Edema; Enzyme Inhibitors; Hyperalgesia; Male; Methylene Blue; Motor Activity; Narcotic Antagonists; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2000 |
L-NAME causes antinociception by stimulation of the arginine-NO-cGMP pathway.
Topics: Analgesics; Animals; Arginine; Carrageenan; Cyclic GMP; Dinoprostone; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxadiazoles; Phosphodiesterase Inhibitors; Phthalazines; Quinoxalines; Rats; Rats, Wistar; Signal Transduction | 2000 |
Neurochemical changes after morphine, dizocilpine or riluzole in the ventral posterolateral thalamic nuclei of rats with hyperalgesia.
Topics: Analysis of Variance; Animals; Arginine; Aspartic Acid; Carrageenan; Citrulline; Dialysis Solutions; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glutamic Acid; Hindlimb; Hyperalgesia; Male; Microdialysis; Morphine; Neuroprotective Agents; Rats; Rats, Wistar; Riluzole; Thalamic Nuclei | 2000 |
Characterization of EP receptor subtypes responsible for prostaglandin E2-induced pain responses by use of EP1 and EP3 receptor knockout mice.
Topics: Animals; Arginine; Behavior, Animal; Dinoprostone; Formaldehyde; Gene Deletion; Hyperalgesia; Mice; Mice, Knockout; Nitric Oxide; Nitroprusside; Nitroso Compounds; Pain; Pain Measurement; Reaction Time; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype | 2001 |
Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Acetic Acid; Analgesia; Animals; Arginine; Carrageenan; Central Nervous System; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dose-Response Relationship, Drug; Female; Hyperalgesia; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Nociceptors; Pain; Pain Measurement; Pain Threshold; Peripheral Nervous System; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Piperazines; Purines; Signal Transduction; Sildenafil Citrate; Sulfones | 2001 |
Antihyperalgesic effects of intrathecal neuropeptide Y during inflammation are mediated by Y1 receptors.
Topics: Acute Disease; Animals; Arginine; Body Temperature; Carrageenan; Disease Models, Animal; Freund's Adjuvant; Hot Temperature; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Neurogenic Inflammation; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide Y; Spinal Cord | 2002 |
Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acid Oxidoreductases; Animals; Arginine; Cycloleucine; Hemoglobins; Hydroxylamine; Hydroxylamines; Hyperalgesia; Ibotenic Acid; Injections, Spinal; Kainic Acid; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Spinal Cord; Time Factors | 1992 |
Antinociceptive effect of L-arginine on the carrageenin-induced hyperalgesia of the rat: possible involvement of central opioidergic systems.
Topics: Analgesics; Animals; Arginine; Blood Pressure; Carrageenan; Hyperalgesia; Male; Motor Activity; Nitric Oxide; Rats; Rats, Inbred Strains; Receptors, Opioid | 1992 |
Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat.
Topics: Analysis of Variance; Animals; Arginine; Hot Temperature; Hyperalgesia; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
L-leucyl-L-arginine, naltrindole and D-arginine block antinociception elicited by L-arginine in mice with carrageenin-induced hyperalgesia.
Topics: Analgesics; Animals; Arginine; Brain; Carrageenan; Dipeptides; Endorphins; Hyperalgesia; Indoles; Injections, Subcutaneous; Male; Mice; Morphinans; Naltrexone; Narcotic Antagonists; Pain Measurement; Stereoisomerism | 1992 |
Teniposide ameliorates bone cancer nociception in rats via the P2X7 receptor.
Topics: Animals; Bone Neoplasms; Carcinoma; Cell Line, Tumor; Cytokines; Disease Models, Animal; Female; Hyperalgesia; Inflammation; Mammary Glands, Animal; Nociception; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Purinergic P2X7; Teniposide | 2018 |