arginine has been researched along with Aging in 482 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 72 (14.94) | 18.7374 |
1990's | 170 (35.27) | 18.2507 |
2000's | 128 (26.56) | 29.6817 |
2010's | 93 (19.29) | 24.3611 |
2020's | 19 (3.94) | 2.80 |
Authors | Studies |
---|---|
Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y | 1 |
Arabzadeh, E; Feizolahi, F; Hatami Nasab, Z; Zargani, M | 1 |
Arabzadeh, E; Feizolahi, F; Mazaheri Tirani, Z; Rahimi, A; Zargani, M | 1 |
Baumann, A; Bergheim, I; Brandt, A; Camarinha-Silva, A; Franzke, B; Hernández-Arriaga, A; Jung, F; Nier, A; Rajcic, D; Schmeer, C; Staltner, R; Wagner, KH; Wessner, B; Witte, OW | 1 |
Andtbacka, RHI; Hyngstrom, JR; Kwon, OS; Noh, SG; Park, SH; Richardson, RS | 1 |
Arc-Chagnaud, C; De la Rosa, A; Guerra-Ojeda, S; Mauricio, MD; San-Miguel, T; Serna, E; Valls, A; Verdú, D; Viña, J | 1 |
Beletti, ME; Butolo, EAF; Butolo, JEG; Oliveira, LBT; Reis, RS; Travençolo, BAN | 1 |
Bijsmans, ES; Biourge, VC; Chang, YM; Elliott, J; Jepson, RE; Sargent, HJ | 1 |
Cifù, A; Curcio, F; Domenis, R; Fabris, M; Garbo, R; Giacomello, R; Gigli, GL; Janes, F; Nilo, A; Pessa, ME; Sanvilli, N; Valente, M | 1 |
Darband, SG; Kaviani, M; Majidinia, M; Mobaraki, K; Sadighparvar, S; Yousefi, B | 1 |
Burrin, DG; Didelija, IC; Marini, JC; Mohammad, MA; Stoll, B; Wang, X | 1 |
Choisy, C; Cynober, L; De Bandt, JP; Le Plenier, S; Nakib, S; Neveux, N; Raynaud-Simon, A; Sarfati, G; Tennoune, N; Ventura, G | 1 |
Hayashi, T | 1 |
Figueroa, A; Gonzales, JU; Jaime, SJ; Moinard, C; Morita, M | 1 |
Arakawa, S; Hayashi, H; Ikeda, R; Kayama, T; Kurosaka, D; Marumo, K; Nagai, R; Ohno, RI; Saito, M; Suzuki, R | 1 |
Engdahl, C; Farman, HH; Gustafsson, KL; Henning, P; Lagerquist, MK; Lawenius, L; Lionikaite, V; Movérare-Skrtic, S; Nilsson, KH; Ohlsson, C | 1 |
Ikegami, S; Kato, H; Nakamura, Y; Nakano, M; Sakai, N; Suzuki, T; Takahashi, J; Tokida, R; Uehara, M | 1 |
Castro-Diehl, C; Ehrbar, R; Obas, V; Oh, A; Vasan, RS; Xanthakis, V | 1 |
Adamski, J; Artati, A; Blaauw, B; Dyar, KA; Huber, S; Möller, G; Tokarz, J; Zeigerer, A | 1 |
Nakamura, Y; Unno, K | 1 |
Chertok, AG; Chertok, VM; Kotsyuba, AE | 1 |
Amancio-Dos-Santos, A; Duda-de-Oliveira, D; Falcão, ACSM; Germano, PCPDS; Guedes, RCA; Maia, LMSS | 1 |
Romanov, GA; Sukhoverov, VS | 1 |
Cao, J; Lei, T; Liu, S; Lu, Z; Shi, L; Wang, H; Zhao, C | 1 |
Bernstein, HG; Laube, G | 1 |
Fujitsuka, N; Hattori, T; Mogami, S; Yamada, C | 1 |
Jönsson, TJ; Kennedy, AD; Milgram, NW; Pan, Y | 1 |
Damanhuri, HA; Hamezah, HS; Jing, Y; Liu, P; Mazlan, M; Taridi, NM; Wan Ngah, WZ; Zhang, H | 1 |
Clay Bunn, R; Creecy, A; Nyman, JS; Unal, M; Uppuganti, S; Voziyan, P | 1 |
Buchalla, W; Grillmeier, I; Hiller, KA; Neubauer, C; Schmalz, G | 1 |
Arnold, P; Bautmans, I; Buyl, R; Gorus, E; Njemini, R; Pool-Goudzwaard, A; Vantieghem, S | 1 |
Esmaeili, M; Gilani, N; Haghshenas, R | 1 |
Brodmann, M; Gary, T; Hackl, G; Hafner, F; Jud, P; Meinitzer, A; Seinost, G; Verheyen, N | 1 |
Amiya, Y; Fujii, H; Katayama, S; Maebuchi, M; Matsui, T; Mitani, T; Nakamura, S; Shimizu, A; Tanaka, M; Tanaka, S | 1 |
Antal, M; Contreras, GA; Dormann, D; Fekecs, Z; Guo, X; Hickman, J; Hortobagyi, T; Horvath, A; Jiang, LL; Karolyi, K; Keresztessy, Z; Kiss, G; Kolostyak, Z; Nagy, L; Nógrádi, A; Pajer, K; Pap, A; Papp, Z; Patsalos, A; Reho, B; Sari, Z; Sieler, T; Simandi, Z; Vámosi, G; Xu, H | 1 |
García-Villanova, B; Guerra-Hernández, E; Hougen, HP; Márquez-Ruiz, AB; Rufián-Henares, JÁ; Valenzuela, A | 1 |
Saito, M; Satake, Y; Takahashi, K; Takai, S | 1 |
Kövamees, O; Mahdi, A; Pernow, J | 1 |
Becker, J; Eickhoff, SB; Mahlke, NS; Reckert, A; Ritz-Timme, S | 1 |
Endo, H; Kajitani, S; Kanazawa, M; Kondo, M; Nakamura, A; Nozaki, E; Sato, K | 1 |
Atawia, RT; Bragg, RT; Caldwell, RW; Fulzele, S; Hamrick, M; Isales, C; Lee, B; Mendhe, B; Pandya, B; Pandya, CD; Toque, HA | 1 |
Imai, T; Kashiwabara, S; Saito, M; Shiraki, M; Tanaka, S | 1 |
Carru, C; Mangoni, AA; McEvoy, M; Rodionov, RN; Sotgia, S; Zinellu, A | 1 |
Baamonde-Laborda, E; Gonzalez-Cabrera, F; Oliva-Damaso, E; Oliva-Damaso, N; Payan, J; Rodriguez-Esparragon, F; Rodriguez-Perez, JC; Santana-Estupiñan, R | 1 |
Bouras, G; Chatzis, G; Cleman, MW; Deftereos, S; Giannopoulos, G; Stefanadis, C; Tousoulis, D; Tsounis, D | 1 |
Karim, L; Sroga, GE; Tang, SY; Vashishth, D | 1 |
Micans, P | 1 |
Basso, A; Costarelli, L; Giacconi, R; Lattanzio, F; Malavolta, M; Mocchegiani, E; Piacenza, F | 1 |
Collie, ND; Fleete, MS; Jing, Y; Liu, P; Zhang, H | 1 |
Chlebda-Sieragowska, E; Fereniec-Gołębiewska, L; Kwiatkowska, J; Merwid-Ląd, A; Pieśniewska, M; Sozański, T; Szeląg, A; Szuba, A; Trocha, M | 1 |
Alcantara, R; Baltgalvis, KA; Claypool, MD; Friera, AM; Godinez, G; Goff, D; Gururaja, T; Hansen, D; Hitoshi, Y; Jenkins, Y; Kinsella, TM; Lang, W; Lau, D; Li, W; Li, Y; Markovtsov, V; McCaughey, K; McLaughlin, J; Nguyen, H; Pan, A; Park, G; Payan, DG; Shaw, SJ; Singh, BK; Singh, R; Smith, IJ; Sun, TQ; Uy, G; White, K | 1 |
Asai, K; Hirata, K; Kanazawa, H; Kyoh, S; Tochino, Y | 1 |
Benno, Y; Kakeyama, M; Kibe, R; Kitada, Y; Kurihara, S; Matsumoto, M; Muramatsu, K; Nakamura, A; Ooga, T; Sakai, Y; Sawaki, E; Suzuki, H; Yamashita, A | 1 |
Abraham, WC; Collie, ND; Curtis, MA; Faull, RL; Fleete, MS; Jing, Y; Liu, P; Waldvogel, HJ; Zhang, H | 1 |
Bayatli, N; Gur, S; Kaya, E; Un, O; Yilmaz, D | 1 |
Chan, WP; Chirkov, YY; Horowitz, JD; Ngo, DT; Sverdlov, AL | 1 |
Kurumatani, N; Obayashi, K; Saeki, K | 1 |
Dhondt, A; Eloot, S; Glorieux, G; Liabeuf, S; Massy, Z; Neirynck, N; Rroji, M; Van Biesen, W; Vandennoortgate, N; Vanholder, R | 1 |
Adams, V; Erbs, S; Gielen, S; Hambrecht, R; Höllriegel, R; Kirsch, K; Linke, A; Lurz, P; Mangner, N; Möbius-Winkler, S; Rabald, K; Sandri, M; Schuler, G; Teupser, D; Thiery, J; Viehmann, M | 1 |
Akhlaghi, A; Esmaeile Neia, L; Lotfi, L; Sharideh, H; Zaghari, M; Zhandi, M | 1 |
Calhoun, D; Dudenbostel, T; Ellis, AC; Gower, B; Patterson, M | 1 |
Ashor, A; Brandt, K; Lara, J; Mathers, JC; Ogbonmwan, I; Oggioni, C; Qadir, O; Siervo, M; Zheng, D | 1 |
Marumo, K; Saito, M | 1 |
Ishigami, A; Machii, H; Miura, S; Owada, T; Saitoh, S; Takeishi, Y; Yamada, S; Yamauchi, H | 1 |
Bowdish, DM; Fei, F; Lee, KM; McCarry, BE | 1 |
Basili, S; Campesi, I; Carru, C; Cherchi, S; Franconi, F; Occhioni, S; Tonolo, G; Zinellu, A | 1 |
Bank, RA; Hooymans, JM; Los, LI; van Deemter, M; Vehof, J | 1 |
Friedrich, MG; Hancock, SE; Raftery, MJ; Truscott, RJ | 1 |
Bendixen, C; Farajzadeh, L; Kristensen, KK; Larsen, K; Momeni, J | 1 |
Dorca, J; Escobar, I; Llatjos, R; Machahua, C; Molina-Molina, M; Montes-Worboys, A; Vicens-Zygmunt, V | 1 |
Bobe, G; Hall, JA; Jewell, DE; Obare, E; Panickar, KS; Yerramilli, M | 1 |
Chen, Z; Cui, K; Liu, J; Luan, Y; Rao, K; Tang, Z; Wang, D; Wang, S; Wang, T | 1 |
Demougeot, C; Guglielmetti, AS; Marie, C; Martin, H; Moretto, J; Prigent-Tessier, A; Tournier-Nappey, M | 1 |
Abe, Y; Arai, Y; Hirata, T; Ohkuma, K; Takayama, M; Takebayashi, T | 1 |
Gongora, E; Nair, N | 1 |
Collie, ND; Gupta, N; Jing, Y; Liu, P; Smith, PF; Zhang, H | 1 |
Blanc, RS; Richard, S | 1 |
Chakraborti, A; Gulati, K; Ray, A | 1 |
Berkowitz, DE; Christianson, DW; Nyhan, D; Santhanam, L | 1 |
Frazão, MF; Guedes, RC; Silva de Seixas Maia, LM | 1 |
Chalisova, NI; Zakutskii, AN | 1 |
Bhattacharya, SK | 1 |
Beaudeux, JL; Cottart, CH; Klimczak, C; Laguillier, C; Nivet-Antoine, V; Sebban, C | 1 |
Chernichovski, T; Grupper, A; Krishtol, N; Laron, I; Schwartz, D; Schwartz, IF | 1 |
Bertholon, C; Chapurlat, R; Gineyts, E; Munoz, F; Sornay-Rendu, E | 1 |
Bank, RA; Hooymans, JM; Los, LI; Ponsioen, TL; Snabel, JM; van Deemter, M; van der Worp, RJ | 1 |
Brummer, RJ; Heitmann, BL; Nieuwenhuizen, AG; van Vught, AJ; Veldhorst, MA; Westerterp-Plantenga, MS | 1 |
Aagaard, P; Couppé, C; Hansen, P; Kjaer, M; Kongsgaard, M; Kovanen, V; Magnusson, SP; Suetta, C | 1 |
Horowitz, JD; McNeil, JJ; Ngo, DT; Sverdlov, AL | 1 |
Liu, A; Ma, Y; Zhu, Z | 1 |
Jing, Y; Liu, P; Zhang, H | 1 |
Bode-Böger, SM; Fulge, B; Heimburg, A; Martens-Lobenhoffer, J; Scalera, F | 1 |
Chernichovski, T; Schwartz, D; Schwartz, IF | 1 |
Dörr, HG; Hauffa, BP; Wallaschofski, H | 1 |
Fahs, CA; Heffernan, KS; Patvardhan, EA; Ranadive, SM | 1 |
Alpert, DR; Cooke, JP; Crow, MK; Devereux, RB; Lockshin, MD; Perna, M; Roman, MJ; Salmon, JE; Sammaritano, L | 1 |
Hegg, CC; Jia, C | 1 |
Abe, T; Isobe, C; Terayama, Y | 1 |
Arnaud, E; Cartoni, R; Chrast, R; Courvoisier, DS; Martinou, JC; Médard, JJ; Poirot, O | 1 |
Hausmanowa-Petrusewicz, I; Kabzińska, D; Kochański, A; Sinkiewicz-Darol, E | 1 |
Devaraj, R; Ganesalingam, GS; Liu, P; Smith, PF; Zhang, H | 1 |
Andley, UP; Reilly, MA | 1 |
Asai, K; Hirata, K; Ichimaru, Y; Kanazawa, H; Kyoh, S; Tochino, Y | 1 |
Eguchi, N; Hirohama, J; Jinno, M; Miyazaki, A; Takeuchi, M; Teruya, K; Watanabe, A | 1 |
Beesley, MF; Choudhary, AK; Clay, S; Conway, BC; Ferenbach, DA; Hughes, J; Kluth, DC; Marson, LP; McKay, J; Nkejabega, NC; Vernon, MA | 1 |
Cremers, SG; Weinberg, PD; Wolffram, SJ | 1 |
Iemitsu, M; Kuno, S; Maeda, S; Murakami, H; Tanabe, K; Zempo, H | 1 |
Bogner, M; Elmadfa, I; Fabian, E | 1 |
Angelim, MK; de França, JP; de Lima e Silva, D; dos Santos, AA; Guedes, RC; Maia, LM; Monteiro, HM | 1 |
Li, LK; Li, XM; Song, B; Wu, XJ; Zhang, JH; Zhou, ZS | 1 |
Jurvelin, JS; Karjalainen, HM; Kokkonen, HT; Korhonen, RK; Kovanen, V; Kulmala, KA; Mäkelä, J; Rieppo, L; Tiitu, V; Töyräs, J | 1 |
Fan, X; Monnier, VM; Nemet, I; Potts, B; Strauch, CM; Xiaoqin, L | 1 |
Cauley, JA; Harris, T; Launer, L; Lindquist, K; Rosano, C; Satterfield, S; Schwartz, AV; Simonsick, EM; Vitartas, C; Vittinghoff, E; Yaffe, K | 1 |
Aussel, C; Cynober, L; Deutz, NE; Jourdan, M | 1 |
Begall, S; Dammann, P; Monnier, VM; Sell, DR; Strauch, C | 1 |
de Boer, TN; DeGroot, J; Huisman, AM; Lafeber, FP; Mastbergen, SC; Polak, AA; Vos, PA | 1 |
Taddei, S; Virdis, A | 1 |
Collie, ND; Jing, Y; Kennard, JT; Liu, P; Rushaidhi, M; Williams, JM; Zhang, H | 1 |
Goto, M; Iwaki-Egawa, S; Watanabe, Y | 1 |
Davidge, ST; Jiang, Y; Lekontseva, O; Schleppe, C | 1 |
Katsanos, CS; Mandarino, LJ; Meyer, C; Puga, GM | 1 |
Collie, ND; Gupta, N; Jing, Y; Liu, P; Zhang, H | 1 |
Aussel, C; Bahri, S; Chaumeil, JC; Crenn, P; Curis, E; Cynober, L; Moinard, C; Sfar, S; Zerrouk, N | 1 |
Aita, S; Iwanaga, T; Kameya, T; Kawai, Y; Matsushita, M; Ogawa, T; Okamoto, N; Saito, M; Yoneshiro, T | 1 |
Bryant-Angeloni, K; Dilger, RN; Lemme, A; Parsons, CM; Payne, RL | 1 |
Attia, JR; Carru, C; Mangoni, AA; McEvoy, M; Zinellu, A | 1 |
Chang, KJ; Choi, MJ | 1 |
Ağar, A; Bîlmen, S; Gümüşlü, S; Hacioğlu, G; Ozdemir, S; Yargiçoğlu, P | 1 |
Horiuchi, S; Jono, T; Kimura, T; Kitamura, T; Miyazaki, K; Nagai, R; Takamatsu, J; Yuzuriha, T | 1 |
Biemel, KM; Conrad, J; Lederer, MO | 1 |
Li, NS; Li, YJ; Lu, R; Peng, J; Zhu, HQ | 1 |
Aimaretti, G; Baffoni, C; Bellone, S; Benso, A; Broglio, F; Corneli, G; Origlia, C; Rovere, S; Tassone, F | 1 |
Allona, A; Angulo, J; Cuevas, P; Fernández, A; Gabancho, S; Martín-Morales, A; Moncada, I; Sáenz de Tejada, I | 1 |
Bode-Böger, SM; Fliser, D; Frölich, JC; Haller, H; Kielstein, JT; Ritz, E | 1 |
Al-Ruzzeh, S; Amrani, M; Chester, AH; Dewar, A; Nakamura, K; Rothery, S; Severs, NJ; Yacoub, MH | 1 |
Corzo, A; Hoehler, D; Moran, ET | 1 |
Anderstam, B; Bárány, P; Fehrman-Ekholm, I; Heimbürger, O; Lindholm, B; Pecoits-Filho, R; Qureshi, AR; Rodríguez Ayala, E; Stenvinkel, P; Suliman, ME | 1 |
Cutler, RG; Handy, A; Ingram, DK; Lane, MA; Mattison, JA; Monnier, VM; Obrenovich, ME; Roth, GS; Sell, DR | 1 |
Bode-Böger, SM; Fliser, D; Haller, H; Kielstein, JT | 1 |
Appleton, I; Bilkey, DK; Darlington, CL; Liu, P; Smith, PF | 1 |
Delemarre-van de Waal, HA; Heine, RJ; van Weissenbruch, MM; Veening, MA | 1 |
Frey, J; Meli, M; Perier, C | 1 |
Selley, ML | 1 |
WALIGORA, Z; WENDER, M | 1 |
MARTINEZ, C | 1 |
Chalisova, NI; Penniiaĭnen, VA | 1 |
Berkowitz, DE; Burke, S; Cernetich, A; Champion, HC; Hare, JM; Kim, S; Li, D; Minhas, KM; Nyhan, D; Shoukas, AA; White, R | 1 |
Bode-Böger, SM; Böger, RH; Brabant, G; Frölich, JC; Muke, J; Surdacki, A | 1 |
Kawata, K; Koga, Y; Mizuguchi, N; Okuda, T; Takasugi, Y; Watanabe, S; Yamanaka, S | 1 |
Boekelheide, K; Gray, DA; Rasoulpour, RJ; Schoenfeld, HA | 1 |
Bencko, V; Bezdícková, D; Pilin, A; Pudil, F; Sajdok, J; Zídková, J | 1 |
Aïtoubah, J; Itaya, S; Molotchnikoff, S | 1 |
Agrawal, CM; Li, X; Shen, X; Wang, X | 1 |
Ohhashi, T; Yashiro, Y | 1 |
Hirao, Y; Kitauchi, T; Ozono, S; Saka, T; Yoneda, T; Yoshida, K; Yoshikawa, M | 1 |
Ahlers, BA; Chin-Dusting, JP; Kaye, DM; Parnell, MM | 1 |
Larson, DF; Watson, RR; Yang, B | 1 |
Boer, P; Braam, B; Goldschmeding, R; Joles, JA; Koomans, HA; Racasan, S; van der Giezen, DM | 1 |
Azuma, H; Kihara, K; Kurosaki, E; Masuda, H; Sakai, Y; Yamauchi, Y | 1 |
Chiariello, M; Coppola, C; Curcio, A; Ellison, GM; Indolfi, C; Leosco, D; Li Volti, G; Rengo, F; Russo, VG; Torella, D; Torella, M | 1 |
Barnett, P; Bonert, VS; Elashoff, JD; Melmed, S | 1 |
Nishimura, H; Ruiz-Feria, CA; Yang, Y | 1 |
Alfarano, C; Banchelli, G; Cecchi, E; Cerbai, E; Cioni, L; Lodovici, M; Mugelli, A; Pirisino, R; Raimondi, L; Sartiani, L; Visioli, F | 1 |
Monnier, VM; Sell, DR | 4 |
Adman, ET; Kamath-Loeb, AS; Loeb, LA; Waite, M; Welcsh, P | 1 |
Ağar, A; Izgüt-Uysal, VN; Ozdemir, S; Ozkaya, YG; Yargiçoğlu, P | 1 |
Bowers, CY; Brill, KT; Mueller, EE; Patrie, JT; Veldhuis, JD; Weltman, A; Weltman, JY | 1 |
Bergamini, E; Bonanomi, G; Cavallini, G; Di Stefano, R; Mosca, F; Odetti, P; Parentini, I; Poggi, A; Rossi, S | 1 |
Menzel, EJ; Reihsner, R | 2 |
Barton, M; Lattmann, T; Münter, K; Shaw, S; Vetter, W | 1 |
Bourguignon, JP; Gérard, A; Lebrethon, MC; Matagne, V | 1 |
Birthelmer, A; Cassel, JC; Förstermann, U; Gödtel-Armbrust, U; Jackisch, R; Knörle, R; Lazaris, A; Schweizer, T | 1 |
Barton, M | 1 |
Hirose, H; Miyashita, K; Ogawa, T; Saito, I; Saruta, T | 1 |
Cavanal, Mde F; Coimbra, TM; Gil, FZ; Gomes, GN; Lucas, SR | 1 |
Habbel, S; Okonek, A; Quack, I; Rump, LC; Stegbauer, J; Vonend, O | 1 |
Calderón-Cortés, E; Clemente-Guerrero, M; Cortés-Rojo, C; Gaona-Zamudio, FJ; Saavedra-Molina, A; Sierra-Campos, E; Villalobos-Molina, R | 1 |
Chung, HY; Kim, YJ; Yokozawa, T | 1 |
Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T | 1 |
Deng, K; Nolan, JV; Wong, CW | 1 |
Barbi, C; Bonafé, M; Franceschi, C; Gravina, S; Mondello, C; Monti, D; Rossi, M; Salvioli, S; Storci, G; Tiberi, L; Tocco, F; Trapassi, C | 1 |
Black, SM; Farrow, KN; Jenkins, C; Konduri, GG; Lakshminrusimha, S; Mata-Greenwood, E; Russell, JA; Steinhorn, RH | 1 |
Ekambaram, P; Paul, V; Reddy, L | 1 |
Böger, RH; Freese, R; Maas, R; Schulze, F; Schwedhelm, E; Silberhorn, E | 1 |
Bowers, CY; Keenan, DM; Mielke, K; Miles, JM; Veldhuis, JD | 1 |
Adegoke, OA; Chevalier, S; Gougeon, R; Lamarche, M; Marliss, EB; Morais, JA; Wu, G | 1 |
Berkowitz, DE; Champion, HC; Hare, JM; Li, D; Nyhan, D; Ryoo, S; Shoukas, AA; Steppan, J; Wang, D; White, AR | 1 |
Holowatz, LA; Kenney, WL; Thompson, CS | 1 |
Aujard, F; Bentivoglio, M; Cayetanot, F; Perret, M | 1 |
Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M | 1 |
Suzuki, J | 1 |
Degroot, J; Maroudas, A; Roughley, P; Sakkee, N; Sivan, SS; Tsitron, E; van der Ham, F; Wachtel, E | 1 |
Bucek, RA; Haider, DG; Hron, G; Kyrle, PA; Minar, E; Mittermayer, F; Reiter, M; Wolzt, M | 1 |
Cipriano, C; Costarelli, L; Giacconi, R; Malavolta, M; Mocchegiani, E; Muti, E; Santarelli, L | 1 |
Boucher, ML; Gates, PE; Monahan, KD; Seals, DR; Silver, AE | 1 |
Babinet, C; Cohen-Tannoudji, M; Domenga, V; Gridley, T; Joutel, A; Langa, F; Lemaire, B; Monet, M; Souilhol, C; Tournier-Lasserve, E | 1 |
Bowers, CY; Cosma, M; Erickson, D; Farhy, LS; Mielke, K; Paulo, R; Veldhuis, JD | 1 |
Dreshaj, IA; Haxhiu, MA; Kamath, S; Martin, RJ; Sopi, RB; Zaidi, SI | 1 |
Carrithers, JA; Haus, JM; Trappe, SW; Trappe, TA | 1 |
Lang, J; Liu, AJ; Ma, YH; Zhang, GR | 1 |
Behnke, BJ; Delp, MD; Muller-Delp, JM; Spier, SA; Wu, G | 1 |
Bencko, V; Bezdícková, D; Pillin, A; Pudil, F | 1 |
De Lutiis, MA; Felaco, M; Franceschelli, S; Grilli, A; Mastrangelo, F; Patruno, A; Pesce, M; Speranza, L; Tetè, S; Vinciguerra, I | 1 |
Barlag, RE; Funovic, P; Jacob, RF; Korda, M; Kubant, R; Malinski, T; Mason, RP | 1 |
Bui, QU; Børsheim, E; Ferrando, AA; Kobayashi, H; Tissier, S; Wolfe, RR | 1 |
Heffernan, KS; Valentine, RJ; Vieira, VJ | 1 |
Huang, CC; Lin, WT; Tsai, SC | 1 |
Zhinkin, LN | 1 |
Frankel, BJ; Gerritsen, GC; Grodsky, GM; Heldt, AM | 1 |
Hill, RS; Rhoten, WB | 1 |
Bolgiano, DC; Halter, JB; McKnight, B; Porte, D; Ward, WK | 1 |
Chyun, JH; Griminger, P | 1 |
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36 review(s) available for arginine and Aging
Article | Year |
---|---|
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction | 2021 |
L-Citrulline Supports Vascular and Muscular Benefits of Exercise Training in Older Adults.
Topics: Aging; Arginine; Biological Availability; Body Mass Index; Citrulline; Dietary Supplements; Endothelium, Vascular; Exercise; Humans; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Nitric Oxide; Oxygen Consumption; Physical Conditioning, Human | 2020 |
Green Tea Suppresses Brain Aging.
Topics: Aging; Animals; Arginine; Brain; Catechin; Glutamates; Humans; Tea | 2021 |
Agmatine: multifunctional arginine metabolite and magic bullet in clinical neuroscience?
Topics: Aging; Agmatine; Animals; Arginine; Central Nervous System Diseases; Humans; Mental Disorders; Metabolic Networks and Pathways; Neuralgia | 2017 |
New horizons in arginine metabolism, ageing and chronic disease states.
Topics: Aged; Aging; Arginine; Chronic Disease; Homoarginine; Humans | 2019 |
Asymmetric (ADMA) and Symmetric (SDMA) Dimethylarginines in Chronic Kidney Disease: A Clinical Approach.
Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic | 2019 |
Asymmetric Dimethylarginine (ADMA): a promising biomarker for cardiovascular disease?
Topics: Aging; Amidohydrolases; Arginine; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Diabetes Complications; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Mass Spectrometry; Nitric Oxide; Oxidative Stress; Reference Values; Risk Factors; Smoking | 2013 |
Is there a possible single mediator in modulating neuroendocrine-thymus interaction in ageing?
Topics: Aging; Animals; Arginine; Cytokines; Humans; Hypothalamo-Hypophyseal System; Melatonin; Mice; Neuroimmunomodulation; Neurosecretory Systems; Signal Transduction; Thymus Gland; Zinc | 2013 |
[Determinants of bone quality and strength independent of bone remodeling].
Topics: Aging; Animals; Arginine; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Collagen; Diphosphonates; Female; Fractures, Stress; Glucocorticoids; Glycation End Products, Advanced; Humans; Lysine; Male; Osteoporosis; Precision Medicine; Selective Estrogen Receptor Modulators | 2016 |
Oxidative Stress and Cardiovascular Aging: Interaction Between NRF-2 and ADMA.
Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction | 2017 |
Regenerating muscle with arginine methylation.
Topics: Aging; Animals; Arginine; Humans; Methylation; Muscle Proteins; Muscles; Muscular Diseases; Myoblasts; Protein-Arginine N-Methyltransferases; Regeneration | 2017 |
Arginase and vascular aging.
Topics: Aging; Animals; Arginase; Arginine; Cardiovascular Agents; Drug Design; Elasticity; Endothelium, Vascular; Enzyme Inhibitors; Humans; Models, Molecular; Nitric Oxide; Nitric Oxide Synthase; Protein Conformation; Signal Transduction; Structure-Activity Relationship | 2008 |
Retinal deimination in aging and disease.
Topics: Aging; Arginine; Humans; Hydrolases; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Retinal Diseases | 2009 |
[Biology of arterial ageing and arteriosclerosis].
Topics: Adult; Aged; Aging; Arginine; Arteriosclerosis; Atherosclerosis; Calcinosis; Diagnostic Techniques, Cardiovascular; Endothelium, Vascular; Extracellular Matrix; Female; Humans; Hypertension; Lipoproteins; Male; Middle Aged; Monocytes; Osteoblasts; Tunica Media; Vascular Resistance | 2009 |
L-arginine as a nutritional prophylaxis against vascular endothelial dysfunction with aging.
Topics: Aging; Anti-Inflammatory Agents; Arginine; Cardiovascular Diseases; Endothelial Cells; Humans; Nitric Oxide; Nutritional Physiological Phenomena; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Endothelial aging and gender.
Topics: Aging; Androgens; Arginine; Atherosclerosis; Endothelium, Vascular; Estrogens; Female; Humans; Nitric Oxide; Reactive Oxygen Species; Sex Factors | 2012 |
Citrulline: from metabolism to therapeutic use.
Topics: Aging; Animals; Arginine; Biological Transport; Cardiovascular Diseases; Citrulline; Humans; Intestinal Mucosa; Models, Animal; Muscle, Skeletal; Protein Biosynthesis; Sarcopenia | 2013 |
Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine?
Topics: Adult; Aged; Aging; Arginine; Enzyme Inhibitors; Humans; Kidney; Kidney Diseases | 2003 |
Native protein glycoxidation and aging.
Topics: Aging; Arginine; Carbohydrate Metabolism; Free Radicals; Glucose; Glycation End Products, Advanced; Glycosylation; Half-Life; Humans; Lysine; Maillard Reaction; Oxidation-Reduction; Proteins | 2003 |
[Age-related post-translational modification of proteins in human tissue and its use determination of age in forensic medicine. Review].
Topics: Aging; Arginine; Forensic Medicine; Glycation End Products, Advanced; Humans; Lysine; Protein Processing, Post-Translational | 2003 |
Ageing as a determinant of renal and vascular disease: role of endothelial factors.
Topics: Aging; Arginine; Endothelial Cells; Endothelium, Vascular; Humans; Kidney Diseases; Nitric Oxide; Vascular Diseases | 2005 |
Plasticity of neuroendocrine-thymus interactions during ontogeny and ageing: role of zinc and arginine.
Topics: Aging; Animals; Arginine; Dietary Supplements; Growth Hormone; Humans; Immune System; Melatonin; Neurosecretory Systems; Rejuvenation; Thymus Gland; Zinc | 2006 |
Microvascular function and ageing L-arginine, tetrahydrobiopterin and the search for the fountain of vascular youth.
Topics: Aging; Animals; Arginine; Arterioles; Biopterins; Endothelium, Vascular; Muscle, Skeletal; Rats; Vasodilation | 2008 |
[Neuroregulation of GH secretion in aging].
Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Child, Preschool; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Infant; Insulin-Like Growth Factor I; Middle Aged; Neuropeptides; Neurotransmitter Agents; Recombinant Proteins; Reference Values; Somatostatin | 1993 |
[Non-enzymatic glycosylation of proteins. Complications of diabetes mellitus, aging and kidney failure].
Topics: Aging; Arginine; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Lysine; Maillard Reaction; Renal Insufficiency | 1993 |
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles | 1996 |
New biomarkers of Maillard reaction damage to proteins.
Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles | 1996 |
Posttranslational arginylation of brain proteins.
Topics: Aging; Amyloid beta-Peptides; Animals; Arginine; Brain; Microtubule-Associated Proteins; Nerve Tissue Proteins; Protein Processing, Post-Translational; Ubiquitins | 1997 |
[Nitric oxide (NO), vascular protection factor. NO: role in aging].
Topics: Aging; Animals; Arginine; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Vasoconstriction | 1998 |
Arginine nutrition and cardiovascular function.
Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Humans; Nitric Oxide; Nutritional Physiological Phenomena | 2000 |
AGE in micro- and macroangiopathy.
Topics: Aging; Animals; Arginine; Arteriosclerosis; Cell Adhesion; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Interferon-gamma; Lysine; Membrane Proteins; Microcirculation; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; T-Lymphocytes; Vascular Diseases | 2001 |
Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia.
Topics: Aging; Arginine; Diabetes Mellitus; Extracellular Matrix Proteins; Humans; Lysine; Maillard Reaction; Proteins; Uremia | 1992 |
Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia.
Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Cross-Linking Reagents; Diabetes Mellitus; Dura Mater; Humans; Lysine; Uremia | 1991 |
Somatomedin C and arginine: implicit connections between mutually isolated literatures.
Topics: Acquired Immunodeficiency Syndrome; Aging; Animals; Arginine; Growth; Growth Hormone; Humans; Insulin-Like Growth Factor I; Nutrition Disorders; Somatomedins | 1990 |
Protein and amino acid requirements of fishes.
Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine | 1986 |
Enzymes of arginine and urea synthesis.
Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Arginase; Arginine; Binding Sites; Carbamates; Dietary Proteins; Humans; Kinetics; Liver; Lyases; Organ Specificity; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Species Specificity; Succinates; Urea | 1973 |
29 trial(s) available for arginine and Aging
Article | Year |
---|---|
Application of multivariate longitudinal models in SIRT6, FBS, and BMI analysis of the elderly.
Topics: Aging; Anthropometry; Arginine; Body Composition; Body Mass Index; Dietary Supplements; Exercise Therapy; Humans; Longevity; Male; Middle Aged; Monitoring, Physiologic; Sirtuins; Treatment Outcome | 2019 |
Aortic wave velocity: a noninvasive method to measure the stiffness of arteries and the clinical results of supplements that appear to improve arterial stiffness.
Topics: Adult; Aged; Aging; Arginine; Cardiovascular Diseases; Carnosine; Dietary Supplements; Female; Glycation End Products, Advanced; Guanidines; Humans; Male; Middle Aged; Pulse Wave Analysis; Resveratrol; Risk Factors; Stilbenes; Vascular Stiffness | 2013 |
Chronic heart failure and aging - effects of exercise training on endothelial function and mechanisms of endothelial regeneration: Results from the Leipzig Exercise Intervention in Chronic heart failure and Aging (LEICA) study.
Topics: Aged; Aging; Arginine; Blood Flow Velocity; Cell Count; Chemokine CXCL12; Endothelial Progenitor Cells; Endothelium, Vascular; Exercise Therapy; Heart Failure; Humans; Intercellular Adhesion Molecule-1; Middle Aged; Prospective Studies; Radial Artery; Regeneration; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A | 2016 |
Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Diet; Female; Fertility; Glycine; Humans; Insemination, Artificial; Male; Sperm-Ovum Interactions; Vitelline Membrane | 2016 |
Effects of 6-month supplementation with β-hydroxy-β-methylbutyrate, glutamine and arginine on vascular endothelial function of older adults.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Brachial Artery; C-Reactive Protein; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Fasting; Female; Glutamine; Humans; Male; Tumor Necrosis Factor-alpha; Valerates; Vasodilation | 2016 |
Effects of handgrip exercise or inorganic nitrate supplementation on 24-h ambulatory blood pressure and peripheral arterial function in overweight and obese middle age and older adults: A pilot RCT.
Topics: Adult; Aged; Aging; Arginine; Beta vulgaris; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dietary Supplements; Exercise; Female; Hand Strength; Humans; Hypertension; Male; Middle Aged; Nitrates; Obesity; Overweight; Phytotherapy; Pulsatile Flow; Treatment Outcome | 2015 |
Nutritional Interventions that Slow the Age-Associated Decline in Renal Function in a Canine Geriatric Model for Elderly Humans.
Topics: Absorptiometry, Photon; Aged; Aging; Animals; Arginine; Biomarkers; Body Weight; Carnitine; Cross-Sectional Studies; Diet; Dietary Proteins; Dietary Supplements; Disease Models, Animal; Dogs; Female; Fish Oils; Fruit; Geriatric Assessment; Glomerular Filtration Rate; Humans; Kidney; Male; Thioctic Acid; Vegetables | 2016 |
Increased plasma availability of L-arginine in the postprandial period decreases the postprandial lipemia in older adults.
Topics: Administration, Oral; Aged; Aging; Arginine; Biological Availability; Cardiovascular Diseases; Dietary Fats; Fatty Acids, Nonesterified; Humans; Hyperlipidemias; Infusions, Intravenous; Male; Postprandial Period; Risk Factors; Triglycerides | 2013 |
Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arginine; Enzyme Inhibitors; Female; Homocysteine; Humans; Male; Matched-Pair Analysis; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Reference Values; Statistics as Topic | 2003 |
Oral L-arginine improves endothelial function in healthy individuals older than 70 years.
Topics: Administration, Oral; Aged; Aging; Analysis of Variance; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Humans; Linear Models; Male; Prospective Studies; Vasodilation | 2003 |
An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans.
Topics: Acetylcholine; Adult; Aged; Aging; Arginine; Biological Transport; Endothelium, Vascular; Forearm; Humans; Male; Middle Aged; Monocytes; Nitric Oxide Synthase; Plethysmography; Reference Values; Vasodilation; Vasodilator Agents | 2004 |
Contributions of gender and systemic estradiol and testosterone concentrations to maximal secretagogue drive of burst-like growth hormone secretion in healthy middle-aged and older adults.
Topics: Aged; Aging; Arginine; Estradiol; Exercise; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Male; Middle Aged; Sex Characteristics; Somatostatin; Stimulation, Chemical; Testosterone | 2004 |
Long-term effects of early life L-arginine supplementation on growth performance, lymphoid organs and immune responses in Leghorn-type chickens.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antibodies; Arginine; Chickens; Dietary Supplements; Immunoglobulin M; Lymphoid Tissue; Male; Serum Albumin, Bovine; Weight Gain | 2005 |
Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy.
Topics: Adipose Tissue; Aged; Aging; Arginine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Luminescence; Male; Middle Aged; Oligopeptides; Radiography, Abdominal; Robotics; Testosterone; Tomography, X-Ray Computed; Viscera | 2005 |
Tripartite control of growth hormone secretion in women during controlled estradiol repletion.
Topics: Adult; Aged; Aging; Arginine; Estradiol; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Middle Aged; Oligopeptides; Postmenopause; Premenopause | 2007 |
Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Drug Combinations; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Infusions, Intravenous; Male; Oligopeptides | 1994 |
Low doses of either intravenously or orally administered arginine are able to enhance growth hormone response to growth hormone releasing hormone in elderly subjects.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Arginine; Dose-Response Relationship, Drug; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Injections, Intravenous; Male | 1994 |
Arginine enhances the growth hormone-releasing activity of a synthetic hexapeptide (GHRP-6) in elderly but not in young subjects after oral administration.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Arginine; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Injections, Intravenous; Insulin-Like Growth Factor I; Male; Molecular Sequence Data; Oligopeptides | 1994 |
Oral arginine-lysine does not increase growth hormone or insulin-like growth factor-I in old men.
Topics: Administration, Oral; Adult; Aged; Aging; Arginine; Drug Combinations; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Lysine; Male; Middle Aged | 1993 |
Age-dependent decrease in the growth hormone response to growth hormone-releasing hormone in normally cycling women.
Topics: Adolescent; Adult; Aging; Arginine; Cholinesterase Inhibitors; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Menstrual Cycle; Middle Aged; Pyridostigmine Bromide; Somatostatin | 1996 |
Aging abolishes the renal response to L-arginine infusion in essential hypertension.
Topics: Adult; Aged; Aging; Arginine; Blood Pressure; Enzyme Inhibitors; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Nitric Oxide; Nitric Oxide Synthase | 1996 |
Effect of arginine and ornithine infusions on luteinizing hormone secretion in prepubertal ewes.
Topics: Aging; Analysis of Variance; Animals; Arginine; Female; Infusions, Intravenous; Luteinizing Hormone; Ornithine; Radioimmunoassay; Sheep | 1996 |
Reproducibility of the growth hormone response to stimulation with growth hormone-releasing hormone plus arginine during lifespan.
Topics: Adult; Aged; Aging; Arginine; Child; Drug Therapy, Combination; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypopituitarism; Male; Reference Values; Reproducibility of Results; Time Factors | 1996 |
Hypertension causes premature aging of endothelial function in humans.
Topics: Acetylcholine; Adult; Aged; Aging; Arginine; Blood Circulation; Drug Interactions; Endothelium; Female; Humans; Hypertension; Male; Middle Aged; Nitroprusside; Vasodilation; Vasodilator Agents | 1997 |
Relationship between mechanical properties and pentosidine in tendon: effects of age, diet restriction, and aminoguanidine in broiler breeder hens.
Topics: Aging; Animals; Arginine; Biomechanical Phenomena; Chickens; Diet; Elasticity; Female; Food Deprivation; Guanidines; Lysine; Regression Analysis; Tendons; Tensile Strength | 2000 |
Retesting young adults with childhood-onset growth hormone (GH) deficiency with GH-releasing-hormone-plus-arginine test.
Topics: Adolescent; Adult; Aging; Arginine; Child; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypopituitarism; Insulin-Like Growth Factor I; Male; Radioimmunoassay | 2000 |
Identification of N(omega)-carboxymethylarginine, a new advanced glycation endproduct in serum proteins of diabetic patients: possibility of a new marker of aging and diabetes.
Topics: Aging; Arginine; Biomarkers; Calibration; Chromatography, Liquid; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Middle Aged; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization | 2001 |
Sensitivity and specificity of six tests for the diagnosis of adult GH deficiency.
Topics: Adult; Aged; Aging; Arginine; Body Mass Index; Diagnostic Techniques, Endocrine; Drug Combinations; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Levodopa; Male; Metabolic Diseases; Middle Aged; Sensitivity and Specificity; Sex Characteristics; Stimulation, Chemical | 2002 |
Effect of normal aging on the prolactin response to graded doses of sulpiride and to arginine.
Topics: Adolescent; Adult; Aged; Aging; Arginine; Humans; Male; Prolactin; Stimulation, Chemical; Sulpiride; Time Factors | 1985 |
417 other study(ies) available for arginine and Aging
Article | Year |
---|---|
Swimming exercise with L-arginine coated nanoparticles supplementation upregulated HAND2 and TBX5 expression in the cardiomyocytes of aging male rats.
Topics: Aging; Animals; Arginine; Dietary Supplements; Humans; Male; Myocytes, Cardiac; Nanoparticles; Physical Conditioning, Animal; Rats; Rats, Wistar; RNA, Messenger; Swimming | 2022 |
Swimming exercise and nano-l-arginine supplementation improve oxidative capacity and some autophagy-related genes in the soleus muscle of aging rats.
Topics: Aging; Animals; Antioxidants; Arginine; Autophagy; Autophagy-Related Proteins; Chitosan; Dietary Supplements; Eosine Yellowish-(YS); Hematoxylin; Male; Muscle, Skeletal; Oxidative Stress; Physical Conditioning, Animal; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Swimming | 2023 |
Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and 'inflammaging'.
Topics: Aging; Animals; Arginase; Arginine; Endotoxemia; Intestines; Mice; Nitric Oxide | 2022 |
Ageing and endothelium-mediated vascular dysfunction: the role of the NADPH oxidases.
Topics: Acetylcholine; Aging; Arginine; Endothelium, Vascular; Humans; Middle Aged; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Vascular Diseases | 2023 |
Glucose 6-P Dehydrogenase Overexpression Improves Aging-Induced Endothelial Dysfunction in Aorta from Mice: Role of Arginase II.
Topics: Aging; Animals; Aorta; Arginase; Arginine; Endothelium, Vascular; Glucose; Glucosephosphate Dehydrogenase; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Vascular Diseases | 2023 |
L-arginine supplementation minimizes aging-induced changes in the sperm chromatin of roosters.
Topics: Aging; Animals; Arginine; Chickens; Chromatin; Diet; Dietary Supplements; Male; Semen; Semen Analysis; Sperm Motility; Spermatozoa | 2023 |
Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats.
Topics: Aging; Animals; Arginine; Biomarkers; Cats; Cross-Sectional Studies; Female; Fibroblast Growth Factors; Male; Reference Values | 2019 |
ADMA as a possible marker of endothelial damage. A study in young asymptomatic patients with cerebral small vessel disease.
Topics: Adult; Aged; Aging; Arginine; Biomarkers; Brain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Endothelial Cells; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Stroke | 2019 |
Combination of exercise training and L-arginine reverses aging process through suppression of oxidative stress, inflammation, and apoptosis in the rat heart.
Topics: Aging; Animals; Apoptosis; Arginine; Fibrosis; Heart; HSP70 Heat-Shock Proteins; Interleukins; Male; Myocardium; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2020 |
Developmental changes in the utilization of citrulline by neonatal pigs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Citrulline; Female; Kidney; Male; Swine | 2020 |
Effect of aging on the availability of amino acids from an immune-enhancing diet (IED) after a surgical stress in rats.
Topics: Aging; Amino Acids; Animals; Arginine; Biological Availability; Enteral Nutrition; Immunity; Male; Models, Animal; Postoperative Care; Rats; Rats, Sprague-Dawley; Stress, Physiological; Surgical Procedures, Operative | 2020 |
[Prevention of the progression of atherosclerosis and aging through nitric oxide (NO)].
Topics: Aging; Animals; Arginine; Atherosclerosis; Citrulline; Humans; Nitric Oxide; Nitric Oxide Synthase; Vasodilation | 2020 |
Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Bone and Bones; Bone Diseases; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Mass Spectrometry; Ornithine; Sex Characteristics; Tartrate-Resistant Acid Phosphatase | 2020 |
Arginine site 264 in murine estrogen receptor-α is dispensable for the regulation of the skeleton.
Topics: Absorptiometry, Photon; Aging; Animals; Arginine; Bone and Bones; Bone Density; Endothelium; Estrogen Receptor alpha; Estrogens; Female; Methylation; Mice; Organ Size; Ovariectomy; Spine; Tibia; Tomography, X-Ray Computed | 2021 |
Reference values for bone metabolism in a Japanese cohort survey randomly sampled from a basic elderly resident registry.
Topics: Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Arginine; Biomarkers; Bone Density; Bone Resorption; Cohort Studies; Female; Femur Neck; Hip; Humans; Japan; Lysine; Male; Middle Aged; Osteoporosis; Reference Values; Registries; Tartrate-Resistant Acid Phosphatase; Vitamin D | 2021 |
Biomarkers representing key aging-related biological pathways are associated with subclinical atherosclerosis and all-cause mortality: The Framingham Study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Intima-Media Thickness; Creatinine; Cross-Sectional Studies; Endothelial Cells; Female; Humans; Insulin-Like Growth Factor I; Isoprostanes; Male; Middle Aged; Oxidative Stress; Prospective Studies; Telomere Homeostasis; Telomere Shortening | 2021 |
Common Muscle Metabolic Signatures Highlight Arginine and Lysine Metabolism as Potential Therapeutic Targets to Combat Unhealthy Aging.
Topics: Aging; Animals; Arginine; Lysine; Male; Mice; Muscle, Skeletal; Oxidative Stress; Signal Transduction | 2021 |
Age-Specific Characteristics of CO-Mediated Reaction of the Pial Arteries of Various Diameters in Rats.
Topics: Aging; Animals; Arginine; Carbon Monoxide; Cerebral Arteries; Hemin; Male; NG-Nitroarginine Methyl Ester; Protoporphyrins; Rats, Wistar; Signal Transduction; Vasodilation | 2017 |
Do the accelerating actions of tianeptine and l-arginine on cortical spreading depression interact? An electrophysiological analysis in young and adult rats.
Topics: Aging; Animals; Arginine; Brain; Brain Mapping; Cortical Spreading Depression; Dose-Response Relationship, Drug; Drug Combinations; Female; Rats, Wistar; Thiazepines | 2017 |
Arginine CGA codons as a source of nonsense mutations: a possible role in multivariant gene expression, control of mRNA quality, and aging.
Topics: Aging; Alternative Splicing; Arginine; Catalase; Codon, Nonsense; DNA Methylation; Gene Expression; Glutamine; Humans; Nonsense Mediated mRNA Decay; RNA, Messenger; Selenocysteine; Selenoproteins | 2017 |
Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.
Topics: Aging; Aldosterone; Amidohydrolases; Animals; Arginine; Cell Line; Creatinine; Diabetes Mellitus, Experimental; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Gene Knockout Techniques; Humans; Kidney Diseases; Kidney Tubules, Proximal; Mice | 2017 |
Peptide YY induces characteristic meal patterns of aged mice.
Topics: Aging; Animals; Appetite; Arginine; Benzazepines; Eating; Feeding Behavior; Male; Mice; Mice, Inbred C57BL; Peptide YY; Receptors, Neuropeptide Y | 2017 |
Cognitive enhancement in old dogs from dietary supplementation with a nutrient blend containing arginine, antioxidants, B vitamins and fish oil.
Topics: Aging; alpha-Tocopherol; Animals; Arginine; Cognition; Cognitive Dysfunction; Diet; Dietary Supplements; Discrimination Learning; Docosahexaenoic Acids; Dog Diseases; Dogs; Eicosapentaenoic Acid; Female; Fish Oils; Learning; Male; Nootropic Agents; Vitamin B Complex | 2018 |
Effects of Aging and Tocotrienol-Rich Fraction Supplementation on Brain Arginine Metabolism in Rats.
Topics: Aging; Amino Acids; Animals; Antioxidants; Arginine; Brain; Dietary Supplements; Male; Polyamines; Rats; Rats, Wistar; Tocotrienols | 2017 |
Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.
Topics: Aging; Animals; Arginine; Bone Density; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Femur; Fractures, Bone; Lysine; Male; Mice; Spectrum Analysis, Raman; X-Ray Microtomography | 2018 |
In vitro effects of hydroxyapatite containing toothpastes on dentin permeability after multiple applications and ageing.
Topics: Aging; Animals; Arginine; Calcium Carbonate; Cattle; Dentin; Dentin Permeability; Dentin Sensitivity; Durapatite; Fluorides; Humans; Nitrates; Potassium Compounds; Saliva; Sodium Fluoride; Toothbrushing; Toothpastes | 2018 |
Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Electromyography; Female; Glycation End Products, Advanced; Humans; Inflammation; Isometric Contraction; Linear Models; Lysine; Male; Muscle Weakness; Muscle, Skeletal; Reaction Time; Sarcopenia; Sex Factors | 2018 |
Age-dependent effects of homocysteine and dimethylarginines on cardiovascular mortality in claudicant patients with lower extremity arterial disease.
Topics: Aged; Aging; Arginine; Austria; Cardiovascular Diseases; Female; Homocysteine; Humans; Incidence; Intermittent Claudication; Lower Extremity; Male; Prospective Studies; Risk Factors; Survival Rate | 2018 |
Soybean-Derived Glycine-Arginine Dipeptide Administration Promotes Neurotrophic Factor Expression in the Mouse Brain.
Topics: Aging; Animals; Arginine; Brain; Brain-Derived Neurotrophic Factor; Dipeptides; Female; Glycine; Glycine max; Hippocampus; Humans; Male; Memory; Mice; Mice, Inbred C57BL; Neurogenesis; Plant Extracts | 2018 |
Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons.
Topics: Aging; Amino Acid Sequence; Animals; Arginine; Cell Line; Cyclic AMP Response Element-Binding Protein; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Isometric Contraction; Male; Mice; Mice, Knockout; Mice, Transgenic; Motor Neurons; Muscle Cells; Neuromuscular Junction; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; Reflex, Abnormal; RNA Interference; RNA, Small Interfering; Rotarod Performance Test; Spinal Cord | 2018 |
Differences in non-enzymatic glycation products in human dentine and clavicle: changes with aging.
Topics: Adolescent; Adult; Age Determination by Skeleton; Age Determination by Teeth; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Clavicle; Dentin; Female; Forensic Sciences; Humans; Lysine; Male; Middle Aged; Young Adult | 2018 |
Objective Colorimetric Evaluation of Aging-related Articular Cartilage Degeneration.
Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Arginine; Cartilage, Articular; Chromatography, High Pressure Liquid; Color; Colorimetry; Female; Glycation End Products, Advanced; Humans; Hydroxyproline; Lysine; Male; Middle Aged; Osteoarthritis; Prospective Studies | 2018 |
Arginase Inhibition Improves Endothelial Function in an Age-Dependent Manner in Healthy Elderly Humans.
Topics: Aged; Aging; Arginase; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Female; Healthy Volunteers; Humans; Male; Middle Aged; Nitric Oxide; Vasodilation | 2019 |
Age estimation based on different molecular clocks in several tissues and a multivariate approach: an explorative study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; D-Aspartic Acid; Epiglottis; Female; Forensic Medicine; Humans; Infant; Intervertebral Disc; Lysine; Male; Middle Aged; Models, Statistical; Multivariate Analysis; Young Adult | 2020 |
Decline of popliteal artery flow-mediated dilation with aging and possible involvement of asymmetric dimethylarginine in healthy men.
Topics: Adult; Age Factors; Aging; Arginine; Brachial Artery; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Popliteal Artery; Reference Values; Sex Factors; Vasodilation | 2019 |
Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice.
Topics: Aging; Animals; Arginase; Arginine; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nitric Oxide; Oxidative Stress | 2019 |
The association of urinary pentosidine levels with the prevalence of osteoporotic fractures in postmenopausal women.
Topics: Aged; Aging; Arginine; Cohort Studies; Cross-Sectional Studies; Female; Humans; Logistic Models; Lysine; Middle Aged; Multivariate Analysis; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Prevalence | 2019 |
Differences in non-enzymatic glycation and collagen cross-links between human cortical and cancellous bone.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Collagen; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Specimen Handling; Tibia; Tissue Culture Techniques; Young Adult | 2013 |
Regional variations and age-related changes in arginine metabolism in the rat brain stem and spinal cord.
Topics: Aging; Animals; Arginine; Blotting, Western; Brain Stem; Male; Rats; Rats, Sprague-Dawley; Spinal Cord | 2013 |
Age-related changes in ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion.
Topics: Aging; Amidohydrolases; Animals; Arginine; Liver; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Transaminases | 2014 |
Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice.
Topics: Aging; AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Arginine; Cilostazol; Diet, High-Fat; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Humans; Intermittent Claudication; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Fatigue; Muscle, Skeletal; Nitric Oxide Synthase Type III; Obesity; Peripheral Vascular Diseases; Phosphodiesterase 3 Inhibitors; Physical Exertion; Tetrazoles; Vasodilator Agents | 2014 |
Potential role of pentosidine on susceptibility to small airway closure in elderly and smoking asthma.
Topics: Adult; Aged; Aging; Arginine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Lysine; Male; Methacholine Chloride; Middle Aged; Respiratory Function Tests; Smoking; Sputum; Vital Capacity; Young Adult | 2014 |
Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice.
Topics: Administration, Oral; Aging; Animals; Arginine; Feces; Female; Intestines; Longevity; Male; Metabolome; Metabolomics; Mice; Microbiota; Polyamines; Probiotics; Putrescine; Quality of Life; Time Factors; Up-Regulation | 2014 |
Altered arginine metabolism in Alzheimer's disease brains.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arginase; Arginine; Cerebellum; Disease Progression; Female; Hippocampus; Humans; Male; Middle Aged; Nitric Oxide Synthase; Organ Specificity; Prefrontal Cortex | 2014 |
L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats.
Topics: Aging; Animals; Arginine; Biopterins; Dose-Response Relationship, Drug; Erectile Dysfunction; Male; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Penile Erection; Penis; Rats, Wistar; Sodium Nitrite | 2014 |
Aging of the nitric oxide system: are we as old as our NO?
Topics: Aged; Aging; Arginine; Blood Platelets; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitric Oxide; Platelet Aggregation; Prospective Studies | 2014 |
Asymmetric dimethylarginine attenuates the association of melatonin secretion with night-time blood pressure and dipping in elderly individuals.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Blood Pressure; Body Mass Index; Circadian Rhythm; Cross-Sectional Studies; Diabetes Mellitus; Endothelium, Vascular; Female; Humans; Hypertension; Male; Melatonin; Nitric Oxide; Nitric Oxide Synthase Type III; Secretory Rate; Smoking | 2014 |
Association of advanced age with concentrations of uraemic toxins in CKD.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; beta 2-Microglobulin; Biomarkers; Blood Urea Nitrogen; Creatinine; Female; Furans; Humans; Male; Middle Aged; Multivariate Analysis; Propionates; Renal Dialysis; Renal Insufficiency, Chronic; Uremia | 2016 |
Senescence marker protein-30 deficiency impairs angiogenesis under ischemia.
Topics: Aging; Animals; Apoptosis; Arginine; Calcium-Binding Proteins; Glutathione; Humans; Intracellular Signaling Peptides and Proteins; Ischemia; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Superoxides; Vascular Endothelial Growth Factor A | 2016 |
Age-associated metabolic dysregulation in bone marrow-derived macrophages stimulated with lipopolysaccharide.
Topics: Aging; Animals; Arginine; Cells, Cultured; gamma-Aminobutyric Acid; Glycolysis; Inflammation; Lipopolysaccharides; Macrophage Activation; Macrophages; Metabolic Diseases; Mice; Mice, Inbred C57BL; Oxidative Phosphorylation; Succinic Acid | 2016 |
Ageing/Menopausal Status in Healthy Women and Ageing in Healthy Men Differently Affect Cardiometabolic Parameters.
Topics: Adult; Aging; Arginine; Blood; Body Weight; Female; Humans; Interleukin-6; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Postmenopause; Premenopause; Protein Carbonylation; Risk Factors; Triglycerides; Tumor Necrosis Factor-alpha | 2016 |
FACTORS ASSOCIATED WITH PENTOSIDINE ACCUMULATION IN THE HUMAN VITREOUS.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Humans; Lysine; Male; Middle Aged; Pseudophakia; Regression Analysis; Sex Factors; Vitreous Body; Vitreous Detachment; Young Adult | 2017 |
Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?
Topics: Adult; Aged; Aging; Arginine; Aspartic Acid; Cerebellum; Glutamine; Humans; Isoaspartic Acid; Mass Spectrometry; Middle Aged; Models, Molecular; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Protein Processing, Post-Translational; Proteolysis | 2016 |
A-to-I RNA editing of the IGFBP7 transcript increases during aging in porcine brain tissues.
Topics: Aging; Amino Acid Sequence; Animals; Arginine; Binding Sites; Brain; Brain Mapping; Cerebellum; Chromosome Mapping; Female; Frontal Lobe; Gene Expression Profiling; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Lung; Lysine; Methylation; Mice; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Sulfates; Swine | 2016 |
Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis.
Topics: Aged; Aging; Alveolar Epithelial Cells; Antigens, Neoplasm; Arginine; Epithelial Cells; Extracellular Matrix Proteins; Female; Fibroblasts; Glycation End Products, Advanced; Humans; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Lung; Lysine; Male; Middle Aged; Mitogen-Activated Protein Kinases; Signal Transduction | 2016 |
Involvement of DDAH/ADMA/NOS/cGMP and COX-2/PTGIS/cAMP Pathways in Human Tissue Kallikrein 1 Protecting Erectile Function in Aged Rats.
Topics: Aging; Amidohydrolases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Erectile Dysfunction; Humans; Intramolecular Oxidoreductases; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tissue Kallikreins | 2017 |
Effects of a chronic l-arginine supplementation on the arginase pathway in aged rats.
Topics: Aging; Animals; Arginase; Arginine; Blood Pressure; Dietary Supplements; Heart Rate; Male; Nitric Oxide; Ornithine; Rats; Rats, Wistar | 2017 |
Carotid Plaque Score and Risk of Cardiovascular Mortality in the Oldest Old: Results from the TOOTH Study.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Female; Humans; Japan; Kaplan-Meier Estimate; Male; Multivariate Analysis; Proportional Hazards Models; Risk Factors; Sensitivity and Specificity; Treatment Outcome | 2018 |
Further studies of the effects of aging on arginine metabolites in the rat vestibular nucleus and cerebellum.
Topics: Aging; Animals; Arginine; Cerebellum; Citrulline; Glutamic Acid; Male; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Vestibular Nuclei | 2017 |
Age related differences in stress-induced neurobehavioral responses in rats: modulation by antioxidants and nitrergic agents.
Topics: Aging; alpha-Tocopherol; Animals; Antioxidants; Arginine; Behavior, Animal; Catalase; Enzyme Inhibitors; Exploratory Behavior; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Superoxide Dismutase | 2008 |
Early malnutrition, but not age, modulates in the rat the L-Arginine facilitating effect on cortical spreading depression.
Topics: Aging; Animals; Arginine; Cortical Spreading Depression; Electroencephalography; Malnutrition; Rats | 2008 |
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation | 2008 |
Sexual dimorphism in glomerular arginine transport affects nitric oxide generation in old male rats.
Topics: Aging; Animals; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cyclic GMP; Female; Kidney Glomerulus; Male; Models, Animal; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Kinase C-alpha; Rats; Rats, Wistar; Sex Characteristics | 2009 |
Urinary levels of pentosidine and the risk of fracture in postmenopausal women: the OFELY study.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone Density; Epidemiologic Methods; Female; Hip Joint; Humans; Lumbar Vertebrae; Lysine; Middle Aged; Osteoporotic Fractures; Postmenopause; Spinal Fractures | 2010 |
Pentosidine accumulates in the aging vitreous body: a gender effect.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Ciliary Body; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Menopause; Middle Aged; Sex Characteristics; Vitreous Body; Young Adult | 2009 |
Association between dietary protein and change in body composition among children (EYHS).
Topics: Adolescent; Aging; Algorithms; Arginine; Body Composition; Body Mass Index; Child; Dietary Proteins; Female; Health Surveys; Humans; Lysine; Male; Motor Activity; Obesity; Puberty; Sex Characteristics; Social Class | 2009 |
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men.
Topics: Adult; Aged; Aging; Amino Acids; Arginine; Arm; Biomechanical Phenomena; Biopsy; Collagen; Glycation End Products, Advanced; Humans; Hydroxyproline; Knee; Lysine; Male; Movement; Muscle, Skeletal; Patellar Ligament; Protein-Lysine 6-Oxidase | 2009 |
Correlates of arterial stiffness in an ageing population: role of asymmetric dimethylarginine.
Topics: Aged; Aging; Arginine; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Vascular Resistance | 2009 |
Protective effect of selenoarginine against oxidative stress in D-galactose-induced aging mice.
Topics: Aging; Animals; Antioxidants; Arginine; Female; Galactose; Glutathione Peroxidase; Male; Malondialdehyde; Mice; Organoselenium Compounds; Oxidative Stress; Superoxide Dismutase | 2009 |
Age-related changes in arginine and its metabolites in memory-associated brain structures.
Topics: Aging; Analysis of Variance; Animals; Arginase; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memory; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley | 2009 |
Red wine decreases asymmetric dimethylarginine via SIRT1 induction in human endothelial cells.
Topics: Age Factors; Aging; Amidohydrolases; Arginine; Cell Survival; Cells, Cultured; Cellular Senescence; Endothelial Cells; Humans; Methyltransferases; Nitric Oxide Synthase; Sirtuin 1; Up-Regulation; Wine | 2009 |
Aortic arginine transport is attenuated, through post-translational modulation of CAT-1 by PKCalpha, in old male rats.
Topics: Age Factors; Aging; alpha-Tocopherol; Animals; Aorta; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Down-Regulation; Female; Male; Nitric Oxide Synthase Type III; Phosphorylation; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Wistar; Up-Regulation | 2010 |
[Management of adolescents with childhood onset growth hormone deficiency in the transition--results of a field based study in Germany].
Topics: Adolescent; Adult; Aging; Arginine; Body Height; Child; Germany; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Physician-Patient Relations | 2009 |
Relationship of asymmetric dimethylarginine and homocysteine to vascular aging in systemic lupus erythematosus patients.
Topics: Adult; Aging; Arginine; Carotid Arteries; Female; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Multivariate Analysis; Patient Selection; Prognosis; Severity of Illness Index; Vascular Diseases | 2010 |
NPY mediates ATP-induced neuroproliferation in adult mouse olfactory epithelium.
Topics: Adenosine Triphosphate; Aging; Animals; Arginine; Cell Proliferation; Dose-Response Relationship, Drug; Male; Mice; Models, Neurological; Neurogenesis; Neuropeptide Y; Olfactory Mucosa; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Neuropeptide Y; Receptors, Purinergic; Sensory Receptor Cells | 2010 |
Decrease in asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in cerebrospinal fluid during elderly aging and in patients with sporadic form of amyotrophic lateral sclerosis.
Topics: Aged; Aging; Amyotrophic Lateral Sclerosis; Analysis of Variance; Anthracenes; Arginine; Case-Control Studies; Female; Humans; Male; Middle Aged; Propane; Statistics, Nonparametric | 2010 |
Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A.
Topics: Aging; Animals; Arginine; Axons; Charcot-Marie-Tooth Disease; DNA, Complementary; Glutamine; GTP Phosphohydrolases; Humans; Membrane Transport Proteins; Mice; Mice, Transgenic; Microscopy, Electron; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Mutation; Nerve Fibers, Myelinated; Neurons; Peripheral Nerves; Phenotype; Sciatic Nerve | 2010 |
Charcot-Marie-Tooth type 1A disease caused by a novel Ser112Arg mutation in the PMP22 gene, coexisting with a slowly progressive hearing impairment.
Topics: Adolescent; Adult; Age of Onset; Aging; Amino Acid Sequence; Amino Acid Substitution; Arginine; Audiometry; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Conserved Sequence; Hearing Disorders; Humans; Male; Molecular Sequence Data; Myelin Proteins; Phenotype; Serine | 2010 |
A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus.
Topics: Aging; Animals; Arginine; Cerebellum; Cluster Analysis; gamma-Aminobutyric Acid; Glutamic Acid; Male; Models, Animal; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Vestibular Nuclei | 2010 |
Quantitative biometric phenotype analysis in mouse lenses.
Topics: Aging; alpha-Crystallin A Chain; Animals; Arginine; Biometry; Cataract; Cysteine; Eye Abnormalities; Genotype; Heterozygote; Homozygote; Image Processing, Computer-Assisted; Lens, Crystalline; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Organ Size; Phenotype; Solubility | 2010 |
Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Asthma; Cross-Linking Reagents; Female; Humans; Lysine; Male; Middle Aged; Respiratory Function Tests; Sputum; Young Adult | 2011 |
Advanced glycation end-products accumulation compromises embryonic development and achievement of pregnancy by assisted reproductive technology.
Topics: Aging; Arginine; Embryo Implantation; Embryonic Development; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicular Fluid; Glycation End Products, Advanced; Humans; Infertility; Lysine; Ovulation Induction; Pregnancy; Pregnancy Rate; Reproductive Techniques, Assisted; Retrospective Studies | 2011 |
The induction of macrophage hemeoxygenase-1 is protective during acute kidney injury in aging mice.
Topics: Acute Kidney Injury; Aging; Animals; Arginine; Cells, Cultured; Heme; Heme Oxygenase-1; Kidney; Macrophages; Membrane Proteins; Mice; Reperfusion Injury | 2011 |
Atheroprotective effects of dietary L-arginine increase with age in cholesterol-fed rabbits.
Topics: Aging; Animals; Arginine; Atherosclerosis; Cholesterol, Dietary; Diet; Rabbits | 2011 |
Age differences in the relation between ACTN3 R577X polymorphism and thigh-muscle cross-sectional area in women.
Topics: Actinin; Age Factors; Aged; Aging; Amino Acid Substitution; Anatomy, Cross-Sectional; Arginine; Asian People; Body Composition; Female; Genetic Association Studies; Humans; Middle Aged; Muscles; Polymorphism, Single Nucleotide; Sex Factors; Thigh | 2011 |
Age-related modification of antioxidant enzyme activities in relation to cardiovascular risk factors.
Topics: Aged; Aged, 80 and over; Aging; Apolipoproteins A; Arginine; Cardiovascular Diseases; Catalase; Enzyme-Linked Immunosorbent Assay; Female; Fetuins; Glutathione Peroxidase; Humans; Lipid Peroxidation; Lipoproteins; Lipoproteins, LDL; Male; Oxidation-Reduction; Oxidative Stress; Risk Factors; Statistics as Topic; Superoxide Dismutase | 2012 |
Differential effects of physical exercise and L-arginine on cortical spreading depression in developing rats.
Topics: Aging; Animals; Arginine; Body Weight; Brain; Cortical Spreading Depression; Dose-Response Relationship, Drug; Histidine; Male; Motor Activity; Organ Size; Rats; Rats, Wistar | 2011 |
Effect of exogenous l-arginine and ageing on NO and ET-1 in penile tissue of rat.
Topics: Aging; Animals; Arginine; Cyclic GMP; Endothelin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Penis; Rats; Rats, Wistar | 2011 |
Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage.
Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Case-Control Studies; Cattle; Collagen; Contrast Media; Hindlimb; Ioxaglic Acid; Lysine; Patella; Tetroses; Tomography, X-Ray Computed | 2011 |
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice.
Topics: Acetylcysteine; Administration, Topical; Aging; Animals; Arginine; Ascorbic Acid; Biological Transport, Active; Cataract; Crystallins; Gene Knock-In Techniques; Glycation End Products, Advanced; Guanidines; Humans; Lens, Crystalline; Mass Spectrometry; Mice; Mice, Transgenic; Ophthalmic Solutions; Penicillamine; Rabbits; Sodium-Coupled Vitamin C Transporters; Spectrometry, Fluorescence | 2011 |
Advanced glycation end product level, diabetes, and accelerated cognitive aging.
Topics: Aged; Aging; Arginine; Chi-Square Distribution; Cognition Disorders; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Longitudinal Studies; Lysine; Male; Mental Status Schedule; Neuropsychological Tests; Odds Ratio | 2011 |
Features, causes and consequences of splanchnic sequestration of amino acid in old rats.
Topics: Age Factors; Aging; Amino Acids; Animals; Arginine; Intestinal Mucosa; Kupffer Cells; Liver; Lysine; Protein Biosynthesis; Rats; Viscera | 2011 |
Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli).
Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Female; Glycation End Products, Advanced; Longevity; Lysine; Male; Mole Rats; Skin | 2012 |
In end stage osteoarthritis, cartilage tissue pentosidine levels are inversely related to parameters of cartilage damage.
Topics: Aged; Aging; Arginine; Arthroplasty, Replacement, Knee; Biomarkers; Cartilage, Articular; Collagen; Female; Glycation End Products, Advanced; Humans; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis, Knee; Severity of Illness Index | 2012 |
Aging affects L-arginine and its metabolites in memory-associated brain structures at the tissue and synaptoneurosome levels.
Topics: Aging; Animals; Arginine; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Chromatography, Liquid; Male; Mass Spectrometry; Memory; Rats; Rats, Sprague-Dawley; Synaptosomes | 2012 |
Ageing in Werner syndrome.
Topics: Adult; Aged, 80 and over; Aging; Arginine; Female; Health; Homocysteine; Humans; Lysine; Male; Middle Aged; Werner Syndrome | 2012 |
Altered neuronal nitric oxide synthase in the aging vascular system: implications for estrogens therapy.
Topics: Aging; Animals; Aorta, Thoracic; Arginine; Blotting, Western; Estradiol; Female; In Vitro Techniques; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Ovariectomy; Rats; Rats, Sprague-Dawley; Superoxides; Tyrosine | 2012 |
Ageing alters behavioural function and brain arginine metabolism in male Sprague-Dawley rats.
Topics: Aging; Animals; Anxiety; Arginase; Arginine; Behavior, Animal; Body Weight; Brain Chemistry; Chromatography, High Pressure Liquid; Cues; Male; Mass Spectrometry; Maze Learning; Memory; Motor Activity; Nitric Oxide Synthase; Orientation; Psychomotor Performance; Rats; Rats, Sprague-Dawley | 2012 |
Impact of UCP1 and β3AR gene polymorphisms on age-related changes in brown adipose tissue and adiposity in humans.
Topics: Adipose Tissue, Brown; Adiposity; Adult; Aged; Aging; Arginine; Energy Metabolism; Female; Fluorodeoxyglucose F18; Healthy Volunteers; Humans; Ion Channels; Japan; Male; Middle Aged; Mitochondrial Proteins; Polymorphism, Single Nucleotide; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Adrenergic, beta-3; Thermogenesis; Tomography, X-Ray Computed; Tryptophan; Uncoupling Protein 1 | 2013 |
Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks.
Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Diet; Glycine | 2013 |
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aging; Amidohydrolases; Arginine; Australia; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Community Medicine; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Taurine | 2013 |
Effect of dietary taurine and arginine supplementation on bone mineral density in growing female rats.
Topics: Aging; Amino Acids; Animals; Arginine; Bone Density; Calcium; Creatinine; Dietary Supplements; Feeding Behavior; Female; Food; Phosphorus; Rats; Rats, Sprague-Dawley; Taurine; Weight Gain | 2013 |
Role of nitric oxide on age-dependent alterations: investigation of electrophysiologic and biochemical parameters.
Topics: Aging; Animals; Antioxidants; Arginine; Brain; Enzyme Inhibitors; Evoked Potentials, Visual; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrous Acid; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E | 2002 |
Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyramidal Cells | 2002 |
Unexpected carbonyl mobility in aminoketoses: the key to major Maillard crosslinks.
Topics: Aging; Amino Sugars; Arginine; Carbon Radioisotopes; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Radioactive Tracers | 2002 |
Endothelium-dependent vasorelaxation and the expression of calcitonin gene-related peptide in aged rats.
Topics: Aging; Animals; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Gene Expression; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilation | 2002 |
The nutritional status has no major role in the age-related reduction of IGF-I secretion.
Topics: Aged; Aging; Arginine; Dehydroepiandrosterone Sulfate; Drug Combinations; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Middle Aged; Nutritional Status; Reference Values | 2002 |
Activation and potentiation of the NO/cGMP pathway by NG-hydroxyl-L-arginine in rabbit corpus cavernosum under normoxic and hypoxic conditions and ageing.
Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Male; Nitric Oxide; Penis; Rabbits; Vasodilation | 2003 |
Asymmetric dimethylarginine, blood pressure, and renal perfusion in elderly subjects.
Topics: Adult; Aged; Aging; Arginine; Blood Pressure; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Renal Circulation; Renal Plasma Flow, Effective | 2003 |
Age-related changes in the protective effect of chronic administration of L-arginine on post-ischemic recovery of endothelial function.
Topics: Aging; Animals; Arginine; Endothelium, Vascular; Male; Models, Animal; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Nitric Oxide; Nitroglycerin; Perfusion; Rats; Rats, Sprague-Dawley; Serotonin; Vasodilator Agents | 2003 |
Arginine need of heavy broiler males: applying the ideal protein concept.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Dietary Proteins; Glycine max; Male; Nitrogen; Nutritional Requirements; Weight Gain; Zea mays | 2003 |
Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Cardiovascular Diseases; Cohort Studies; Female; Glomerular Filtration Rate; Humans; Inflammation; Kidney Failure, Chronic; Lysine; Male; Mortality; Nutrition Disorders; Prognosis; Prospective Studies; Renal Dialysis; Survival Analysis | 2003 |
The effect of caloric restriction on glycation and glycoxidation in skin collagen of nonhuman primates.
Topics: Aging; Analysis of Variance; Animals; Arginine; Biomarkers; Body Weight; Chromatography, High Pressure Liquid; Collagen; Food Deprivation; Glucose; Glucose Tolerance Test; Glycation End Products, Advanced; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Regression Analysis; Saimiri; Skin | 2003 |
Regional variations and age-related changes in nitric oxide synthase and arginase in the sub-regions of the hippocampus.
Topics: Aging; Animals; Arginase; Arginine; Dentate Gyrus; Down-Regulation; Hippocampus; Liver; Male; Memory Disorders; Nerve Degeneration; Neurons; Nitric Oxide; Nitric Oxide Synthase; Protein Isoforms; Rats; Rats, Sprague-Dawley; Up-Regulation; Urea | 2003 |
Beta-cell capacity and insulin sensitivity in prepubertal children born small for gestational age: influence of body size during childhood.
Topics: Aging; Arginine; Birth Weight; Body Constitution; Body Mass Index; Child; Female; Growth; Humans; Infant, Newborn; Infant, Small for Gestational Age; Insulin; Insulin Secretion; Islets of Langerhans; Male | 2003 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
[ARGINASE ACTIVITY DURING THE EMBRYONIC DEVELOPMENT OF THE ALBINO RAT (RATTUS NORWEGICUS)].
Topics: Aging; Amniotic Fluid; Arginase; Arginine; Blood; Brain; Embryo, Mammalian; Embryo, Nonmammalian; Female; Liver; Ornithine; Placenta; Pregnancy; Proteins; Rats; Research; Urea | 1963 |
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen | 2003 |
Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.
Topics: Aging; Animals; Arginase; Arginine; Blood Vessels; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents | 2003 |
Strain differences to effects of aging on concentrations of amino acids in cerebrospinal fluid between Sprague Dawley rat and Wistar Kyoto rat.
Topics: Aging; Amino Acids; Animals; Arginine; Body Weight; Male; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Threonine | 2003 |
Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging.
Topics: Aging; Animals; Animals, Newborn; Arginine; Cell Death; Cryptorchidism; Cytoprotection; Gene Expression; Humans; Lysine; Male; Mice; Mice, Transgenic; Mutation; Spermatogenesis; Spermatozoa; Testis; Transgenes; Ubiquitin | 2003 |
Nitric oxide and its influence on oscillations of collicular responses in developing rats.
Topics: Aging; Animals; Animals, Newborn; Arginine; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Evoked Potentials; Immunohistochemistry; Models, Neurological; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Periodicity; Rats; Rats, Long-Evans; Superior Colliculi | 2003 |
Age-related changes of noncalcified collagen in human cortical bone.
Topics: Adult; Aged; Aging; Arginine; Bone Remodeling; Cadaver; Collagen; Cross-Linking Reagents; Elasticity; Female; Femoral Fractures; Femur; Haversian System; Humans; Lysine; Male; Middle Aged; Osteogenesis; Osteoporosis; Protein Denaturation | 2003 |
Age-dependent changes in the regulatory roles of nitric oxide and vasodilator prostanoids on the mechanical activities of isolated rabbit spinal arterioles.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Age Factors; Aging; Animals; Arginine; Arterioles; Cilostazol; Dose-Response Relationship, Drug; Epoprostenol; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Prostaglandins; Rabbits; Spinal Cord; Tetrazoles; Vasodilation; Vasodilator Agents | 2003 |
Association between pentosidine and arteriosclerosis in patients receiving hemodialysis.
Topics: Aged; Aging; Aorta, Abdominal; Aortic Diseases; Arginine; Arteriosclerosis; Calcinosis; Female; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Regression Analysis; Renal Dialysis; Time Factors; Tomography, X-Ray Computed | 2004 |
Modulation of iNOS activity in age-related cardiac dysfunction.
Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Guanidines; Isothiuronium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Ventricular Dysfunction, Left | 2004 |
Perinatal L-arginine and antioxidant supplements reduce adult blood pressure in spontaneously hypertensive rats.
Topics: Aging; Animals; Animals, Newborn; Antioxidants; Arginine; Blood Pressure; Dietary Supplements; Female; Hypertension; Kidney; Male; Nitric Oxide; Oxidative Stress; Pregnancy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species | 2004 |
Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit.
Topics: Aging; Animals; Arginase; Arginine; Carbachol; Cholinergic Agonists; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits | 2004 |
Aging exacerbates negative remodeling and impairs endothelial regeneration after balloon injury.
Topics: Aging; Angioplasty, Balloon; Animals; Apoptosis; Arginine; Cell Cycle Proteins; Cell Division; Endothelium, Vascular; Hyperplasia; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Regeneration | 2004 |
Body mass index determines evoked growth hormone (GH) responsiveness in normal healthy male subjects: diagnostic caveat for adult GH deficiency.
Topics: Adult; Aging; Arginine; Body Mass Index; Case-Control Studies; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Obesity; Time Factors | 2004 |
Do incremental increases in blood pressure elicit neointimal plaques through endothelial injury?
Topics: Aging; Animals; Aorta, Abdominal; Arginine; Blood Pressure; Chickens; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Hypertension; Male; Propranolol; Solvents; Tunica Intima | 2004 |
n-3 polyunsaturated fatty acids supplementation decreases asymmetric dimethyl arginine and arachidonate accumulation in aging spontaneously hypertensive rats.
Topics: Aging; Animals; Arachidonic Acid; Arginine; Cardiovascular Diseases; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Male; Rats; Rats, Inbred SHR; Risk Factors | 2005 |
Conversion of arginine into ornithine by advanced glycation in senescent human collagen and lens crystallins.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alkylation; Arginine; Borohydrides; Child; Chromatography, Liquid; Collagen; Crystallins; Formaldehyde; Furans; Glycation End Products, Advanced; Glycosylation; Humans; Hydrolysis; Lens, Crystalline; Middle Aged; Ornithine; Skin; Spectrometry, Mass, Electrospray Ionization | 2004 |
The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aging; Alleles; Arginine; Cell Line; Cysteine; DNA; DNA Helicases; DNA, Complementary; Escherichia coli; Exodeoxyribonucleases; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Humans; Hydrolysis; Immunoprecipitation; Models, Genetic; Models, Molecular; Mutation; Plasmids; Polymorphism, Genetic; Protein Structure, Tertiary; RecQ Helicases; Transfection; Werner Syndrome Helicase | 2004 |
Effect of L-arginine on age-related changes in macrophage phagocytic activity.
Topics: Aging; Animals; Arginine; Macrophages, Peritoneal; Male; Nitric Oxide; Phagocytosis; Rats; Rats, Wistar | 2004 |
Changes in dolichol and pentosidine levels in the age-mismatched heterotopically transplanted rat heart.
Topics: Aging; Animals; Arginine; Biological Clocks; Connective Tissue; Dolichols; Heart Transplantation; Lysine; Male; Myocardium; Papillary Muscles; Rats; Rats, Inbred Lew; Transplantation, Heterotopic | 2004 |
The influence of L-arginine on biomechanical parameters of native and nonenzymatically glycated rat tail tendons.
Topics: Aging; Animals; Arginine; Calcium; Collagen; Dose-Response Relationship, Drug; Elasticity; Glucose; Glycation End Products, Advanced; Glycosylation; Male; Models, Biological; Molecular Structure; Protein Binding; Proteoglycans; Rats; Rats, Sprague-Dawley; Sodium; Tail; Tendons; Tensile Strength; Weight-Bearing | 1994 |
Anatomically distinct activation of endothelin-3 and the L-arginine/nitric oxide pathway in the kidney with advanced aging.
Topics: Aging; Animals; Arginine; Blood Pressure; Body Weight; Endothelin-3; Female; Gene Expression Regulation; Kidney; Nitric Oxide; Rats; Rats, Wistar; Receptors, Endothelin; Signal Transduction | 2005 |
Kainate/estrogen receptor involvement in rapid estradiol effects in vitro and intracellular signaling pathways.
Topics: Aging; Animals; Arginine; Estradiol; Estrogen Receptor alpha; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Male; Median Eminence; Nitric Oxide; Preoptic Area; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, Glutamate; Receptors, Kainic Acid; Signal Transduction | 2005 |
Cognitive deficits in aged rats correlate with levels of L-arginine, not with nNOS expression or 3,4-DAP-evoked transmitter release in the frontoparietal cortex.
Topics: 4-Aminopyridine; Acetylcholine; Aging; Amifampridine; Animals; Arginine; Cerebral Cortex; Cognition Disorders; Female; Frontal Lobe; Gene Expression Regulation; Nerve Tissue Proteins; Neurotransmitter Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Parietal Lobe; Rats; Rats, Long-Evans; Serotonin | 2005 |
GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men.
Topics: Adult; Aged; Aging; Arginine; Body Mass Index; Genotype; Histidine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Japan; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, G-Protein-Coupled; Regression Analysis | 2005 |
Effects of intrauterine food restriction and long-term dietary supplementation with L-arginine on age-related changes in renal function and structure of rats.
Topics: Actins; Aging; Animals; Arginine; Blood Pressure; Dietary Supplements; Female; Fetal Growth Retardation; Fibronectins; Food Deprivation; Glomerular Filtration Rate; Glomerulonephritis; Immunohistochemistry; Kidney; Placental Insufficiency; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Proteinuria; Rats; Rats, Wistar; Time Factors; Weight Gain | 2005 |
Renovascular effects of sympathetic cotransmitters ATP and NPY are age-dependent in spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Aging; Animals; Arginine; Dose-Response Relationship, Drug; Electric Stimulation; Kidney; Male; Neuropeptide Y; Norepinephrine; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Receptors, Purinergic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System | 2005 |
Functional characterization of brain mitochondrial nitric oxide synthase during hypertension and aging.
Topics: Aging; Animals; Arginine; Brain; Citrulline; Hypertension; Indazoles; Male; Mitochondria; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar | 2006 |
Effects of energy restriction and fish oil supplementation on renal guanidino levels and antioxidant defences in aged lupus-prone B/W mice.
Topics: Acetic Acid; Aging; Animals; Antioxidants; Arginine; Catalase; Creatinine; Dietary Supplements; Energy Intake; Female; Fish Oils; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Guanidine; Kidney; Lupus Vulgaris; Mice; Mice, Inbred Strains; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase | 2005 |
Immunohistochemical localization of advanced glycation end products in pinguecula.
Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles | 2006 |
Ornithine is a novel amino acid and a marker of arginine damage by oxoaldehydes in senescent proteins.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Child; Collagen; Glycation End Products, Advanced; Humans; Middle Aged; Ornithine; Skin Aging | 2005 |
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; beta-Galactosidase; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Separation; Cells, Cultured; Chromatin Immunoprecipitation; Codon; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Flow Cytometry; Homozygote; Humans; Luciferases; Microscopy, Fluorescence; Neoplasms; Oligonucleotides; Oxidative Stress; Polymorphism, Genetic; Proline; Propidium; Protein Isoforms; Transfection | 2005 |
eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally.
Topics: Aging; Animals; Arginine; Biopterins; Calcimycin; Endothelium, Vascular; Enzyme Activation; Fetus; HSP90 Heat-Shock Proteins; Humans; Nitric Oxide Synthase Type III; Pulmonary Artery; Reactive Oxygen Species; Recombinant Proteins; Sheep; Stress, Mechanical; Superoxides; Vascular Endothelial Growth Factor A; Vasodilation | 2006 |
A reversal by L-arginine and sodium nitroprusside of ageing-induced memory impairment in rats by increasing nitric oxide concentration in the hippocampus.
Topics: Aging; Animals; Arginine; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Hippocampus; Male; Memory Disorders; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Reaction Time; Rotation; Time Factors | 2005 |
Determination of a reference value for N(G), N(G)-dimethyl-L-arginine in 500 subjects.
Topics: Adult; Aged; Aging; Arginine; Biomarkers; Cardiovascular Diseases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Reference Values; Sensitivity and Specificity; Sex Characteristics | 2005 |
Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Blood Glucose; Body Composition; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Obesity; omega-N-Methylarginine; Proteins; Regression Analysis; Sex Characteristics | 2006 |
Knockdown of arginase I restores NO signaling in the vasculature of old rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Arginase; Arginine; Calcium; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotides, Antisense; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Up-Regulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2006 |
L-Arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin.
Topics: Adolescent; Adult; Aged; Aging; Arginase; Arginine; Biological Availability; Female; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Skin; Up-Regulation; Vasodilation | 2006 |
Age-related effects on the biological clock and its behavioral output in a primate.
Topics: Aging; Animals; Arginine; Behavior, Animal; Biological Clocks; Cheirogaleidae; Circadian Rhythm; Neuropeptides; Peptides; Primates; Suprachiasmatic Nucleus; Time Factors; Vasoactive Intestinal Peptide; Vasopressins | 2006 |
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.
Topics: Aging; Arginine; Cells, Cultured; Cellular Senescence; Endothelial Cells; Endothelium, Vascular; Homocysteine; Humans; NG-Nitroarginine Methyl Ester; Oxidative Stress; Telomerase; Time Factors | 2006 |
L-arginine supplementation causes additional effects on exercise-induced angiogenesis and VEGF expression in the heart and hind-leg muscles of middle-aged rats.
Topics: Aging; Animals; Arginine; Blotting, Western; Capillaries; Coronary Vessels; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Heart Ventricles; Hindlimb; Histocytochemistry; Male; Muscle, Skeletal; Myocardium; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Physical Conditioning, Animal; Rats; Rats, Wistar; Vascular Endothelial Growth Factor A | 2006 |
Age-related accumulation of pentosidine in aggrecan and collagen from normal and degenerate human intervertebral discs.
Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Chondroitin Sulfate Proteoglycans; Collagen; Discitis; Extracellular Matrix Proteins; Humans; Intervertebral Disc; Lectins, C-Type; Lysine; Middle Aged; Proteoglycans | 2006 |
The cardiovascular risk marker asymmetrical dimethylarginine is not affected by venous thromboembolism.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Body Mass Index; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Middle Aged; Risk Factors; Venous Thrombosis | 2006 |
Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression.
Topics: Adolescent; Adult; Aged; Aging; Amidohydrolases; Arginine; Biological Availability; Brachial Artery; Carotid Arteries; Endothelium, Vascular; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Regional Blood Flow; Vasodilation | 2007 |
The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo.
Topics: Aging; Animals; Arginine; CADASIL; Cerebral Arteries; Cysteine; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Intracranial Arterial Diseases; Lac Operon; Mice; Mice, Knockout; Mutant Proteins; Mutation, Missense; Protein Structure, Tertiary; Receptor, Notch3; Receptors, Notch; Transgenes | 2007 |
Disruption of NO-cGMP signaling by neonatal hyperoxia impairs relaxation of lung parenchyma.
Topics: Aging; Animals; Animals, Newborn; Arginase; Arginine; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Hyperoxia; In Vitro Techniques; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction | 2007 |
Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle.
Topics: Actins; Activities of Daily Living; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Collagen; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Muscle Contraction; Muscle Strength; Muscular Diseases; Myofibrils; Myosins; Quadriceps Muscle | 2007 |
[Effect of seleno-arginine on cellular immunological function in D-gal aging mice].
Topics: Aging; Animals; Arginine; CD40 Antigens; Cell Proliferation; Dietary Supplements; Female; Fluorescent Antibody Technique; Galactose; Gene Expression Regulation; Killer Cells, Natural; Male; Mice; Selenium; Spleen; Thymus Gland | 2007 |
Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles.
Topics: Aging; Animals; Arginase; Arginine; Arterioles; Biopterins; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pterins; Rats; Rats, Inbred F344; Vasodilation | 2008 |
Contents of pentosidine in the tissue of the intervertebral disc as an indicator of the human age.
Topics: Adolescent; Adult; Age Determination by Skeleton; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Glycation End Products, Advanced; Humans; Intervertebral Disc; Lumbar Vertebrae; Lysine; Middle Aged | 2007 |
iNOS activity in the aged rat liver tissue.
Topics: Aging; Animals; Arginine; Blotting, Western; Citrulline; Gene Expression; Immunohistochemistry; Kidney; Liver; Male; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Effect of beta-blockers on endothelial function during biological aging: a nanotechnological approach.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; Arginine; Atenolol; Cellular Senescence; Endothelium, Vascular; In Vitro Techniques; Metoprolol; Nanotechnology; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Pterins; Rats; Rats, Inbred WKY; Superoxide Dismutase | 2008 |
Effect of amino acid supplementation on muscle mass, strength and physical function in elderly.
Topics: Absorptiometry, Photon; Aged; Aging; Amino Acids, Essential; Arginine; Body Composition; Dietary Supplements; Female; Gait; Glucose Intolerance; Humans; Lower Extremity; Male; Muscle Strength; Muscle Strength Dynamometer; Muscle, Skeletal; Treatment Outcome | 2008 |
Potential ergogenic effects of L-arginine against oxidative and inflammatory stress induced by acute exercise in aging rats.
Topics: Aging; Animals; Arginine; Biomarkers; Dietary Supplements; Inflammation; Kidney; Lactic Acid; Liver; Lung; Male; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Peroxidase; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Xanthine Oxidase | 2008 |
[Protein synthesis and the regulation process in the cell].
Topics: Aging; Animals; Arginine; Autoradiography; Axons; Body Weight; Cell Biology; Cytoplasmic Granules; Glycine; Golgi Apparatus; Guinea Pigs; Hippocampus; Homeostasis; Leucine; Methionine; Mice; Microscopy, Electron; Neurons; Pancreas; Photoreceptor Cells; Protein Biosynthesis; Purkinje Cells; Pyramidal Tracts; Rats; Ribosomes; RNA; RNA, Messenger; Spectrophotometry; Thyroid Gland; Time Factors; Tritium; Tyrosine | 1966 |
Insulin, glucagon, and somatostatin release from the prediabetic Chinese hamster.
Topics: Aging; Animals; Arginine; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mutation; Prediabetic State; Somatostatin | 1984 |
Differential effects of microtubule-altering agents on beta-cells during development.
Topics: Aging; Animals; Arginine; Deuterium; Deuterium Oxide; Female; Fetus; Gestational Age; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Microtubules; Pregnancy; Rats; Rats, Inbred Strains; Vinblastine; Water | 1983 |
Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.
Topics: Adult; Aging; Arginine; Blood Glucose; Catecholamines; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Obesity | 1984 |
Improvement of nitrogen retention by arginine and glycine supplementation and its relation to collagen synthesis in traumatized mature and aged rats.
Topics: Aging; Animals; Arginine; Collagen; Food, Fortified; Glycine; Hydroxyproline; Male; Nitrogen; Rats; Rats, Inbred F344; Wound Healing; Wounds and Injuries | 1984 |
Urinary excretion of dimethylarginines in premature infants.
Topics: Adolescent; Adult; Aging; Arginine; Body Weight; Child; Child, Preschool; Diet; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Methylhistidines; Muscle Proteins; Nitrogen; Proteins | 1984 |
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine | 1982 |
Serum glucagon after arginine infusion in aged and young subjects.
Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Diabetes Mellitus; Glucagon; Growth Hormone; Humans; Infusions, Parenteral; Insulin | 1980 |
Hormonal control of glucose homeostasis during development and ageing in mice.
Topics: Aging; Animals; Arginine; Blood Glucose; Catecholamines; Cortisone; Glucagon; Growth Hormone; Homeostasis; Hormones; Insulin; Mice; Mice, Obese | 1982 |
Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain.
Topics: Adenine; Aging; Animals; Animals, Newborn; Arginine; Blood-Brain Barrier; Brain; Butanols; Choline; Glucose; Lactates; Permeability; Rabbits; Tryptophan | 1982 |
Effect of dietary arginine level on urinary orotate and citrate excretion in growing kittens.
Topics: Aging; Animals; Arginine; Cats; Citrates; Diet; Dose-Response Relationship, Drug; Female; Male; Nutritional Requirements; Orotic Acid | 1980 |
Arginyl-tRNA transferase activity as a marker of cellular aging in peripheral rat tissues.
Topics: Acyltransferases; Aging; Aminoacyltransferases; Animals; Arginine; Brain; Chromatin; Chromosomal Proteins, Non-Histone; Kidney; Liver; Male; Rats; RNA, Transfer; Tissue Distribution | 1980 |
Developmental changes of free amino acid concentrations in fetal fluids of pigs.
Topics: Aging; Allantois; Amino Acids; Ammonia; Amniotic Fluid; Animals; Arginine; Female; Fetal Blood; Gestational Age; Glutamine; Glycine; Male; Ornithine; Placenta; Pregnancy; Swine; Urea; Uterus | 1995 |
Nitric oxide and beta-adrenergic mechanisms modify contractile responses to norepinephrine in ovine fetal and newborn cerebral arteries.
Topics: Adrenergic beta-Antagonists; Aging; Animals; Animals, Newborn; Arginine; Cerebral Arteries; Embryonic and Fetal Development; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Propranolol; Receptors, Adrenergic, beta; Sheep; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity.
Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1995 |
The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Humans; Hypertrophy; Inflammation; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Mice, Mutant Strains; Obesity; Sex Characteristics; Time Factors | 1995 |
Age-dependent decrease in endothelium-dependent hyperpolarizations to endothelin-3 in the rat mesenteric artery.
Topics: Acetylcholine; Aging; Animals; Arginine; Endothelins; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitroarginine; Rats; Rats, Inbred WKY | 1993 |
Effect of ageing on tissue levels of amino acids involved in the nitric oxide pathway in rat brain.
Topics: Aging; Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Aspartic Acid; Brain Chemistry; Citrulline; Glutamates; Glutamic Acid; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar | 1993 |
Different pial arteriolar responses to acetylcholine in the newborn and juvenile pig.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Arterioles; Calcimycin; Cerebrovascular Circulation; Cyclic GMP; Female; Male; Nitroarginine; Nitroprusside; Pia Mater; Swine | 1994 |
Abolition of flow-dependent EDRF release before that evoked by agonists in hypercholesterolaemic rabbits.
Topics: Acetylcholine; Aging; Animals; Arginine; Blood Viscosity; Cholesterol; Cholesterol, Dietary; Dextrans; Hypercholesterolemia; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits | 1994 |
Effect of aging on nitric oxide-mediated penile erection in rats.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Papaverine; Penile Erection; Penis; Rats; Rats, Inbred F344 | 1995 |
Nitric oxide synthesis and the effect of aminoguanidine and NG-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Diabetes Mellitus, Type 1; Guanidines; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred BB; Species Specificity; Time Factors | 1995 |
N omega-nitro-L-arginine methyl ester reduces the incidence of IDDM in BB/E rats.
Topics: Administration, Oral; Aging; Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 1; Female; Insulin; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred BB | 1995 |
Impairment of the priming effect of glucose on insulin secretion from isolated islets of aging rats.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Blood Glucose; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Sprague-Dawley | 1995 |
Endothelial nucleotide-mediated aorta relaxation in aged Watanabe heritable hyperlipidemic rabbits.
Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Aorta, Thoracic; Arginine; Arteriosclerosis; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hyperlipidemia, Familial Combined; Male; Methylene Blue; Microscopy, Electron; Microscopy, Electron, Scanning; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinergic Antagonists; Rabbits; Receptors, Muscarinic; Receptors, Purinergic; Suramin; Uridine Triphosphate | 1995 |
Effect of aging and hypertension on contractility of resistance arteries: modulation by endothelial factors.
Topics: Aging; Angiotensins; Animals; Arginine; Arteries; Blood Pressure; Body Weight; Endothelium, Vascular; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents | 1995 |
Arginine synthesis in enterocytes of neonatal pigs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Body Fluids; Citrulline; DNA; Glutamine; Jejunum; Kidney; Ornithine; Osmolar Concentration; Proline; Swine | 1995 |
Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen.
Topics: Aging; Animals; Arginine; Blood Proteins; Chromatography, High Pressure Liquid; Collagen; Energy Intake; Female; Food Deprivation; Glycation End Products, Advanced; Lysine; Oxidation-Reduction; Rats; Rats, Inbred BN; Skin | 1995 |
Roles of nitric oxide and endothelium-derived hyperpolarizing factor in vasorelaxant effect of acetylcholine as influenced by aging and hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Biological Factors; Blood Pressure; Hypertension; In Vitro Techniques; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation; Tetraethylammonium Compounds; Vasodilation | 1995 |
An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele.
Topics: Aging; Alanine; Alleles; Animals; Apoptosis; Arginine; Cell Differentiation; Codon; Epithelial Cells; Gene Expression; Genes, p53; Genetic Therapy; Humans; Lens, Crystalline; Mice; Mice, Transgenic; Microphthalmos; Point Mutation; Proline; Tumor Suppressor Protein p53; Valine | 1995 |
Role of nitric oxide in regulation of vascular resistance in postnatal intestine.
Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Infusions, Intra-Arterial; Intestines; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Oxygen; Partial Pressure; Potassium Chloride; Regional Blood Flow; Swine; Vascular Resistance | 1995 |
Evidence for the Maillard reaction in rat lung collagen and its relationship with solubility and age.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Extracellular Matrix; Hydroxyproline; Lung; Lysine; Maillard Reaction; Rats; Rats, Sprague-Dawley; Solubility; Spectrometry, Fluorescence | 1995 |
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Rats; Signal Transduction | 1993 |
The suppression of long-term potentiation in rat hippocampus by inhibitors of nitric oxide synthase is temperature and age dependent.
Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Hemoglobins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Temperature | 1993 |
Vasomotor reactivity and catecholamine, arginine vasopressin plasma levels during ageing and development in rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Arterial Occlusive Diseases; Blood Pressure; Carotid Artery Diseases; Catecholamines; Hyperlipidemias; Hypertension; Isoproterenol; Norepinephrine; Rats; Rats, Inbred Strains; Vasomotor System; Vasopressins | 1994 |
Age-related changes in vascular reactivity in genetically diabetic rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Calcimycin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker | 1995 |
The role of islet secretory function in the development of diabetes in the GK Wistar rat.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Glyceraldehyde; Glycerol; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Potassium Chloride; Rats; Rats, Wistar; Reference Values | 1994 |
Developmental effects of endothelin-1 on the pulmonary circulation in sheep.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Arginine; Endothelins; Glyburide; Hemodynamics; Hypertension, Pulmonary; Meclofenamic Acid; Nitric Oxide; Nitroarginine; Potassium Channel Blockers; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pulmonary Circulation; Sheep; Thromboxane A2; Vasoconstrictor Agents | 1994 |
Effects of aging and caloric restriction on extracellular matrix biosynthesis in a model of injury repair in rats.
Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Dipeptides; Energy Intake; Granulation Tissue; Lysine; Male; Rats; Rats, Inbred F344; Time Factors; Wound Healing | 1995 |
Effect of 15-day treatment with growth-hormone-releasing hormone alone or combined with different doses of arginine on the reduced somatotrope responsiveness to the neurohormone in normal aging.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Arginine; Dose-Response Relationship, Drug; Drug Combinations; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Injections, Intravenous; Male; Reference Values; Time Factors | 1995 |
Lysyl oxidase and Maillard reaction-mediated crosslinks in aging and osteoarthritic rabbit cartilage.
Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Collagen; Female; Lysine; Maillard Reaction; Osteoarthritis; Peptide Mapping; Protein-Lysine 6-Oxidase; Rabbits; Solubility | 1995 |
Glutamine and glucose metabolism in enterocytes of the neonatal pig.
Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Arginine; Citrulline; Glucose; Glutamine; Jejunum; Oxygen Consumption; Swine | 1995 |
The possible role and treatment of deficient microcirculation regulation in age-associated memory impairment.
Topics: Acetylcholine; Aging; Animals; Arginine; Arterioles; Brain; Cerebrovascular Circulation; Drug Tolerance; Endothelium, Vascular; Humans; Hypertension; Memory Disorders; Microcirculation; Models, Biological; Nitric Oxide; Vasodilator Agents | 1994 |
Changes in nitric oxide precursor, L-arginine, and metabolites, nitrate and nitrite, with aging.
Topics: Aging; Animals; Arginine; Fasting; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley | 1994 |
Blunted growth hormone response to intravenous arginine in subjects with a spinal cord injury.
Topics: Adult; Aging; Arginine; Body Mass Index; Glucose Tolerance Test; Growth Hormone; Humans; Insulin-Like Growth Factor I; Kinetics; Middle Aged; Spinal Cord Injuries | 1994 |
L-arginine-nitric oxide pathway and chronic nephropathy in aged rats.
Topics: Aging; Amino Acids; Animals; Arginine; Blood Urea Nitrogen; Chronic Disease; Creatinine; Dietary Proteins; Dilatation, Pathologic; Guanidines; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Inbred F344; Sclerosis; Specific Pathogen-Free Organisms | 1994 |
Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction.
Topics: Adult; Aged; Aging; Arginine; Erectile Dysfunction; Humans; Male; Middle Aged; Nitric Oxide; Penis; Pilot Projects; Regional Blood Flow | 1994 |
Hypertension and ageing impair acetylcholine-induced vasodilation in rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Blood Pressure; Hemodynamics; Hypertension; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasodilation | 1994 |
Altered renal vascular responses in the aging rat kidney.
Topics: Aging; Angiotensin II; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Endothelins; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Renal Circulation; Tetrazoles | 1994 |
Nitric oxide production and neurotoxicity mediated by activated microglia from human versus mouse brain.
Topics: Aged; Aging; Animals; Animals, Newborn; Arginine; Brain; Cells, Cultured; gamma-Aminobutyric Acid; Humans; Interferon-gamma; L-Lactate Dehydrogenase; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Microglia; Middle Aged; Neurons; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1994 |
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Norepinephrine; Ouabain; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Yohimbine | 1994 |
Functional versus structural changes in the pathophysiology of acute ischemic renal failure in aging rats.
Topics: Acute Kidney Injury; Aging; Animals; Arginine; Dietary Proteins; Glomerular Filtration Rate; Ischemia; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiourea | 1994 |
Glutamate and theta-rhythm stimulation selectively enhance NMDA component of EPSC in CA1 neurons of young rats.
Topics: Aging; Animals; Arginine; Evoked Potentials; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitroarginine; Norepinephrine; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Theta Rhythm | 1993 |
Influence of age and long-term dietary restriction on enzymatically mediated crosslinks and nonenzymatic glycation of collagen in mice.
Topics: Aging; Animals; Aorta; Arginine; Collagen; Cross-Linking Reagents; Food Deprivation; Glycosylation; Lung; Lysine; Male; Mice; Mice, Inbred C57BL; Skin; Spectrometry, Fluorescence; Tendons | 1994 |
L-arginine reduces kidney collagen accumulation and N-epsilon-(carboxymethyl)lysine in the aging NMRI-mouse.
Topics: Aging; Animals; Arginine; Basement Membrane; Collagen; Electrophoresis, Polyacrylamide Gel; Female; Glycosylation; Hydroxyproline; Kidney; Kidney Glomerulus; Lysine; Mice | 1994 |
Quantitative analysis of crosslinks pyridinoline and pentosidine in articular cartilage of patients with bone and joint disorders.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Bone Diseases; Cartilage, Articular; Chromatography, High Pressure Liquid; Chronic Kidney Disease-Mineral and Bone Disorder; Cross-Linking Reagents; Female; Femur Head Necrosis; Hip Joint; Humans; Joint Diseases; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis; Osteoporosis | 1994 |
Pulmonary endothelial nitric oxide production is developmentally regulated in the fetus and newborn.
Topics: Aging; Animals; Animals, Newborn; Arginine; Cyclic GMP; Embryonic and Fetal Development; Endothelium, Vascular; Fetus; In Vitro Techniques; Nitric Oxide; Oxygen; Pulmonary Artery; Sheep | 1993 |
Role of endothelium-derived nitric oxide in control of renal microvasculature in aging male rats.
Topics: Aging; Animals; Arginine; Arterioles; Blood Pressure; Glomerular Filtration Rate; Hematocrit; Kidney Glomerulus; Male; Microcirculation; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Renal Circulation; Vascular Resistance | 1993 |
Differential effects of type 2 (non-insulin-dependent) diabetes mellitus on pentosidine formation in skin and glomerular basement membrane.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Basement Membrane; Biomarkers; Child; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Female; Humans; Infant; Kidney Glomerulus; Lysine; Male; Middle Aged; Skin; Skin Aging | 1993 |
Effects of repeated stress on plasma arginine levels in young and old rats.
Topics: Adaptation, Psychological; Aging; Animals; Arginine; Immobilization; Male; Rats; Rats, Inbred F344; Stress, Psychological | 1993 |
Spontaneous glucose intolerance in the progeny of low dose streptozotocin-induced diabetic mice.
Topics: Aging; Animals; Arginine; Body Weight; Diabetes Mellitus, Experimental; Female; Glucose; Glucose Intolerance; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Pancreatic Diseases; Pregnancy; Pregnancy in Diabetics; Sex Factors; Species Specificity | 1993 |
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine | 1993 |
Modulation by aging of the coronary vascular response to endothelin-1 in the rat isolated perfused heart.
Topics: Acetylcholine; Aging; Animals; Arginine; Coronary Circulation; Coronary Vessels; Endothelins; Hemoglobins; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; Nitroprusside; Perfusion; Prostaglandins; Rats; Rats, Inbred F344 | 1993 |
Developmental and biochemical characteristics of the cardiac membrane-bound arginine-specific mono-ADP-ribosyltransferase.
Topics: ADP Ribose Transferases; Aging; Animals; Arginine; Bacillus cereus; Cell Membrane; Glycosylphosphatidylinositols; Heart; Myocardium; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Species Specificity | 1993 |
Quantification of the cross-link pentosidine in serum from normal and uremic subjects.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Uremia | 1993 |
Decreased arteriolar endothelium-derived relaxing factor production during the development of genetic hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Arterioles; Hypertension; Male; Microcirculation; Muscles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stimulation, Chemical | 1993 |
Hypersecretion of amylin from the perfused pancreas of genetically obese (fa/fa) rats and its alteration with aging.
Topics: Aging; Amyloid; Animals; Arginine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Male; Obesity; Pancreas; Perfusion; Rats; Rats, Zucker; Reference Values | 1993 |
Angiotensin II-induced endothelium-dependent relaxation of fowl aorta.
Topics: Acetylcholine; Aging; Angiotensin II; Animals; Aorta; Arginine; Calcium; Endothelium, Vascular; Female; Gossypol; Hydroquinones; NG-Nitroarginine Methyl Ester; Poultry; Vasoconstrictor Agents; Vasodilation | 1993 |
GLUT2 expression and function in beta-cells of GK rats with NIDDM. Dissociation between reductions in glucose transport and glucose-stimulated insulin secretion.
Topics: Aging; Animals; Arginine; Biological Transport; Cell Membrane; Diabetes Mellitus, Type 2; Gene Expression; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; RNA, Messenger; Species Specificity | 1993 |
Accumulation of Maillard reaction products in skin collagen in diabetes and aging.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Diabetes Mellitus, Type 1; Female; Glycosylation; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Oxidation-Reduction; Skin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1993 |
Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence.
Topics: Aging; Animals; Arginine; Cattle; Collagen; Cross-Linking Reagents; Diet; Dogs; Glucose; Humans; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Rats; Regression Analysis; Saimiri; Skin; Swine | 1996 |
Secretion of insulin and glucagon by the perfused pancreas of genetically obese (fa/fa) Zucker rats and its alteration with aging.
Topics: Aging; Animals; Arginine; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Radioimmunoassay; Rats; Rats, Zucker | 1995 |
Restoration of normal adult penile erectile response in aged rats by long-term treatment with androgens.
Topics: Aging; Androgens; Animals; Arginine; Blotting, Western; Dihydrotestosterone; Drug Implants; Electric Stimulation; Enzyme Inhibitors; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Pressure; Rats; Rats, Inbred F344; Testosterone | 1995 |
Beyond the somatopause: growth hormone deficiency in adults over the age of 60 years.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Body Mass Index; Female; Growth Hormone; Humans; Hypothalamic Diseases; Insulin-Like Growth Factor I; Male; Middle Aged; Pituitary Diseases; Reference Values | 1996 |
Activation of nitric oxide synthesis in vascular smooth muscle cells and macrophages during development in spontaneously hypertensive rats.
Topics: Aging; Animals; Arginine; Blood Pressure; Cell Division; Cells, Cultured; Concanavalin A; Enzyme Inhibitors; Hypertension; Lymphocytes; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Spleen | 1996 |
Phenotypic expressions of a Gly 154Arg mutation in type II collagen in two unrelated patients with spondyloepimetaphyseal dysplasia (SEMD).
Topics: Adult; Aging; Amino Acid Sequence; Arginine; Base Sequence; Bone and Bones; Bone Development; Collagen; Female; Genotype; Glycine; Humans; Infant, Newborn; Male; Molecular Sequence Data; Osteochondrodysplasias; Pedigree; Phenotype; Point Mutation; Polymerase Chain Reaction; Radiography; Spine | 1996 |
Ageing is associated with reduced basal and stimulated release of nitric oxide by the coronary endothelium.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Male; Nitric Oxide; omega-N-Methylarginine; Perfusion; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents | 1996 |
Arg506Gln factor V mutation and cerebral ischemia in the young.
Topics: Adolescent; Adult; Aging; Arginine; Brain Ischemia; Child; Child, Preschool; Factor V; Female; Glycine; Humans; Male; Point Mutation | 1996 |
The performance of commercial broilers when fed various levels of rendered whole-hen meal.
Topics: Aging; Animal Feed; Animals; Arginine; Body Weight; Chickens; Diet; Eating; Food Handling; Food Preservation; Tryptophan | 1996 |
Direct quantification of pentosidine in urine and serum by HPLC with column switching.
Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Time Factors; Uremia | 1996 |
The role of glycation cross-links in diabetic vascular stiffening.
Topics: Adult; Aged; Aging; Amino Acids; Aorta, Thoracic; Arginine; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Elastin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Time Factors | 1996 |
Subcellular distribution of soluble and membrane-bound Arg-beta-naphthylamide hydrolyzing activities in the developing and aged rat brain.
Topics: Aging; Aminopeptidases; Animals; Arginine; Brain; Cell Membrane; Female; Hydrolysis; Male; Microsomes; Myelin Proteins; Rats; Rats, Sprague-Dawley; Synaptosomes | 1995 |
Comparison of 5-hydroxy-2-amino valeric acid with carbonyl group content as a marker of oxidized protein in human and mouse liver tissues.
Topics: Aging; Amino Acids; Animals; Arginine; Biomarkers; Carboxylic Acids; Cytosol; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Proline; Proteins; Regression Analysis; Sensitivity and Specificity; Spectrometry, Mass, Secondary Ion | 1996 |
A diet enriched in protein accelerates diabetes manifestation in NOD mice.
Topics: Aging; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Dietary Proteins; Female; Glucose Tolerance Test; Incidence; Insulin; Insulin Secretion; Mice; Mice, Inbred NOD | 1996 |
Arginine degradation in developing porcine enterocytes.
Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Aging; Animals; Animals, Newborn; Animals, Suckling; Arginine; Cells, Cultured; Citrulline; Cyclohexanecarboxylic Acids; Intestinal Mucosa; Jejunum; Nitric Oxide Synthase; Nitroarginine; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroline Carboxylate Reductases; Swine; Valine; Weaning | 1996 |
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Hydroxyproline; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lysine; Male; Oxidation-Reduction; Random Allocation; Rats; Rats, Inbred BB; Spectrometry, Fluorescence | 1996 |
Aging-associated endothelial dysfunction in humans is reversed by L-arginine.
Topics: Acetylcholine; Adult; Aged; Aging; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Humans; Male; Microcirculation; Middle Aged; Nitroglycerin; Papaverine; Vasodilator Agents | 1996 |
Abdominal adiposity and physical fitness are major determinants of the age associated decline in stimulated GH secretion in healthy adults.
Topics: Abdomen; Adipose Tissue; Adult; Aging; Arginine; Body Constitution; Clonidine; Female; Growth Hormone; Humans; Male; Middle Aged; Oxygen Consumption; Physical Fitness; Reference Values; Regression Analysis | 1996 |
[Activity of basic arginine- and lysine-residue cleaving carboxypeptidase in rats of various ages].
Topics: Aging; Animals; Arginine; Brain; Carboxypeptidases; Hydrolysis; Lysine; Male; Rats | 1996 |
Influence of dietary lysine levels and arginine:lysine ratios on performance of broilers exposed to heat or cold stress during the period of three to six weeks of age.
Topics: Aging; Animals; Arginine; Body Composition; Body Temperature; Chickens; Cold Temperature; Diet; Dose-Response Relationship, Drug; Eating; Hot Temperature; Lysine; Male; Meat; Poultry Diseases; Regression Analysis; Stress, Physiological; Time Factors; Weight Gain | 1997 |
Age-related increase in an advanced glycation end product in penile tissue.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Penile Erection; Penis; Sexual Dysfunction, Physiological | 1995 |
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Arterial Occlusive Diseases; Cyclic GMP; Disease Progression; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peripheral Vascular Diseases; Vasodilation | 1997 |
Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs.
Topics: Aging; Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbon Dioxide; Cells, Cultured; DNA; Enzyme Induction; Female; Glucocorticoids; Glutamine; Hydrocortisone; Jejunum; Male; Mifepristone; Ornithine; Proline; Receptors, Glucocorticoid; Swine; Urea; Weaning | 1997 |
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays | 1997 |
Synthesis of citrulline and arginine from proline in enterocytes of postnatal pigs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Carbon Radioisotopes; Citrulline; Female; Intestinal Mucosa; Male; Mitochondria; Models, Biological; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Radioisotope Dilution Technique; Rats; Swine | 1997 |
Basal and stimulated nitric oxide in control of kidney function in the aging rat.
Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Renal Circulation; Vascular Resistance; Vasoconstriction | 1997 |
Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function.
Topics: Aging; Animals; Arginine; Body Weight; Cell Movement; Diet; Hemodynamics; Kidney; Kidney Glomerulus; Macrophages; Male; Nitrates; Nitrites; Organ Size; Proteinuria; Rats; Renal Circulation; Sclerosis; Time Factors | 1997 |
Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons.
Topics: Adolescent; Aged; Aging; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipofuscin; Lysine; Nerve Degeneration; Nerve Tissue Proteins; Neurons | 1997 |
Aging and severity of hypertension attenuate endothelium-dependent renal vascular relaxation in humans.
Topics: Adult; Aged; Aging; Arginine; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Osmolar Concentration; Renal Circulation; Vasodilation | 1997 |
[L-arginine nitric oxide pathway in acute renal ischemia reperfusion injury of the aged rats].
Topics: Aging; Animals; Arginine; Cyclic GMP; Ischemia; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renal Agents; Reperfusion Injury | 1996 |
Age-related association of tail tendon break time with tissue pentosidine in DBA/2 vs C57BL/6 mice: the effect of dietary restriction.
Topics: Aging; Animals; Arginine; Collagen; Diet; Female; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Denaturation; Species Specificity; Tail; Tendons; Time Factors | 1997 |
Effect of dietary aminoguanidine on tissue pentosidine and reproductive performance in broiler breeder hens.
Topics: Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Chickens; Collagen; Diet; Egg Shell; Female; Fertility; Guanidines; Lysine; Male; Oviposition; Random Allocation; Reproduction; Skin; Specific Gravity | 1997 |
Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diaphyses; Dipeptides; Femur; Histidine; Humans; Indicators and Reagents; Infant; Lysine; Male; Middle Aged; Sensitivity and Specificity; Skin; Spectrometry, Fluorescence | 1997 |
Neurochemical development of the degenerating rat retina.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamine; Glycine; Immunohistochemistry; Neurotransmitter Agents; Rats; Rats, Inbred BUF; Rats, Mutant Strains; Retina; Retinal Degeneration; Taurine | 1997 |
Apparent ileal digestibilities of amino acids in newly weaned pigs fed diets with protease-treated soybean meal.
Topics: Administration, Topical; Aging; Alanine; Amino Acids; Animals; Arginine; Diet; Dietary Proteins; Digestion; Endopeptidases; Female; Glycine max; Hydrogen-Ion Concentration; Ileum; Male; Swine; Weaning | 1997 |
Arginine supplementation increases weight gain, depresses antibody production, and alters circulating leukocyte profiles in preruminant calves without affecting plasma growth hormone concentrations.
Topics: Aging; Animals; Animals, Newborn; Antibody Formation; Arginine; Cattle; Diet; Dietary Supplements; Growth Hormone; Hemocyanins; Immunoglobulin G; Insulin-Like Growth Factor Binding Protein 3; Leukocytes; Male; Nitrogen; Radioimmunoassay; Random Allocation; Urea; Weight Gain | 1997 |
Basal synthesis of heat shock protein 70 increases with age in rat kidneys.
Topics: Actins; Aging; Animals; Arginine; HSP70 Heat-Shock Proteins; Kidney; Lysine; Male; Rats; Rats, Wistar; RNA, Messenger; RNA, Ribosomal | 1998 |
Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomechanical Phenomena; Cartilage, Articular; Child; Child, Preschool; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Hydroxylysine; Infant; Lysine; Middle Aged; Protein Processing, Post-Translational | 1998 |
Nonenzymatic glycation of cartilage proteoglycans: an in vivo and in vitro study.
Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Animals; Arginine; Cartilage; Cartilage, Articular; Cattle; Chromatography, Agarose; Cross-Linking Reagents; Extracellular Matrix Proteins; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Lectins, C-Type; Lysine; Middle Aged; Molecular Weight; Osteoarthritis; Proteoglycans | 1997 |
Role of nitric oxide-related mechanisms in renal function in ageing rats.
Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Arginine; Glomerular Filtration Rate; Hemodynamics; Kidney; Kidney Function Tests; Male; Microspheres; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar | 1998 |
Role of advanced glycation end products in aging collagen. A scanning force microscope study.
Topics: Aging; Animals; Arginine; Collagen; Glycation End Products, Advanced; Lysine; Male; Microscopy; Osmolar Concentration; Periodicity; Rats; Rats, Wistar; Tail; Tendons | 1998 |
Collagen crosslinks in human lumbar intervertebral disc aging.
Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cadaver; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged | 1998 |
The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.
Topics: Adult; Aging; Alleles; Arginine; Body Mass Index; Body Temperature Regulation; Body Weight; Cholesterol; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Genotype; Humans; Lipolysis; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Random Allocation; Receptors, Adrenergic, beta; Tryptophan | 1998 |
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats.
Topics: Acetylcholine; Aging; Animals; Aorta; Arginine; Blood Pressure; Bradykinin; Calcium; Cattle; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents | 1998 |
Localization of identified advanced glycation end-product structures, N epsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Brain; Entorhinal Cortex; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Inclusion Bodies; Lipofuscin; Lysine; Maillard Reaction; Middle Aged; Ubiquitins | 1998 |
Influence of age, hyperglycemia, leptin, and NPY on islet blood flow in obese-hyperglycemic mice.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretion; Islets of Langerhans; Leptin; Mice; Mice, Inbred C57BL; Mice, Obese; Neuropeptide Y; Obesity; Organ Size; Pancreas; Perfusion; Phlorhizin; Proteins; Receptors, Leptin; Receptors, Neuropeptide Y; Regional Blood Flow | 1998 |
Hexarelin, a synthetic GH-releasing peptide, is a powerful stimulus of GH secretion in pubertal children and in adults but not in prepubertal children and in elderly subjects.
Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Child, Preschool; Female; Growth Hormone-Releasing Hormone; Growth Substances; Human Growth Hormone; Humans; Male; Middle Aged; Oligopeptides; Puberty | 1998 |
Determination of urinary and serum pentosidine and its application to elder patients.
Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Humans; Lysine; Middle Aged | 1998 |
Effects of continuous ambulatory peritoneal dialysis and kidney transplantation on advanced glycation endproducts in the skin and peritoneum.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Skin; Spectrometry, Fluorescence | 1998 |
Chemical modification of proteins by methylglyoxal.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Aorta; Arginine; Child; Collagen; Crystallins; Diabetes Mellitus, Type 1; Dogs; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged; Proteins; Pyruvaldehyde; Rats; Skin; Uremia | 1998 |
Changes in collagen cross-linking in degenerative disc disease and scoliosis.
Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dipeptides; Extracellular Matrix; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged; Scoliosis | 1998 |
Decrease in participation of nitric oxide in nonadrenergic, noncholinergic relaxation of rat intestine with age.
Topics: Adrenergic Agents; Aging; Animals; Arginine; Atropine; Colon; Electric Stimulation; Enzyme Inhibitors; Female; Guanethidine; Humans; Ileum; Immunohistochemistry; In Vitro Techniques; Infant, Newborn; Intestines; Jejunum; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Rats; Rats, Wistar; Rectum; Time Factors | 1998 |
Prolonged L-arginine on cardiovascular mass and myocardial hemodynamics and collagen in aged spontaneously hypertensive rats and normal rats.
Topics: Aging; Animals; Aorta; Arginine; Collagen; Coronary Circulation; Coronary Vessels; Fibrosis; Heart; Heart Ventricles; Hemodynamics; Hypertension; Male; Muscle Development; Muscle, Smooth, Vascular; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Vascular Resistance; Ventricular Function, Left | 1999 |
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia | 1999 |
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bruch Membrane; Choroid; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Infant; Lysine; Middle Aged; Pigment Epithelium of Eye; Retinal Drusen | 1999 |
Protein glycosylation and advanced glycosylated endproducts (AGEs) accumulation: an avian solution?
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Enzyme Inhibitors; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Hyperglycemia; Leukocytes; Lysine; Oxidative Stress; Random Allocation; Respiratory Burst; Skin; Uric Acid | 1999 |
Age-related decrease in proteoglycan synthesis of human articular chondrocytes: the role of nonenzymatic glycation.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Cross-Linking Reagents; Extracellular Matrix; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Osteoarthritis; Proteoglycans; Ribose | 1999 |
Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus, Type 1; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred NOD | 1999 |
Lysylhydroxylation and non-reducible crosslinking of human supraspinatus tendon collagen: changes with age and in chronic rotator cuff tendinitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Child; Chronic Disease; Collagen; Cross-Linking Reagents; Humans; Hydroxylation; Hydroxylysine; Lysine; Middle Aged; Rotator Cuff; Tendinopathy | 1999 |
Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.
Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aging; Animals; Antibodies; Antibody Specificity; Arginine; Bruch Membrane; Cattle; Choroid Plexus; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infant; Lysine; Middle Aged | 1999 |
Characterization and regional distribution of nitric oxide synthase in the human brain during normal ageing.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Brain; Cadaver; Child; Child, Preschool; Citrulline; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reference Values; Tissue Distribution | 1999 |
Expression of the genes of arginine-synthesizing enzymes in the rat kidney during development.
Topics: Aging; Animals; Animals, Newborn; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Blotting, Northern; Gene Expression; Glucocorticoids; Intestines; Kidney; Liver; Rats; Rats, Wistar; RNA, Messenger; Tissue Distribution; Transcription, Genetic | 1999 |
DNA sequence variants of p53: cancer and aging.
Topics: Aged; Aged, 80 and over; Aging; Arginine; Codon; Genes, p53; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Middle Aged; Neoplasms; Odds Ratio; Polymorphism, Genetic; Proline | 1999 |
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo.
Topics: Aging; Animals; Antioxidants; Arabinose; Arginine; Cattle; Cross-Linking Reagents; Diabetes Mellitus; Fluorescence; Glucose; In Vitro Techniques; Lysine; Maillard Reaction; Oxidation-Reduction; Oxygen; Pentoses; Proteins; Ribonucleases | 1999 |
Adult and fetal haemoglobin J-Sardegna [alpha50(CE8)His-->Asp]: functional and molecular modelling studies.
Topics: 2,3-Diphosphoglycerate; Adult; Aging; Amino Acid Substitution; Arginine; Aspartic Acid; Binding Sites; Computer Simulation; Crystallography, X-Ray; Fetal Blood; Genetic Variation; Hemoglobin J; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Models, Molecular; Oxygen; Temperature; Thermodynamics; Time Factors | 2000 |
Effect of age and menopause on serum concentrations of pentosidine, an advanced glycation end product.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Lysine; Menopause; Middle Aged; Osteocalcin | 2000 |
Accumulation of advanced glycation endproducts in aging male Fischer 344 rats during long-term feeding of various dietary carbohydrates.
Topics: Aging; Animals; Arginine; Blood Glucose; Collagen; Cross-Linking Reagents; Dietary Carbohydrates; Dietary Sucrose; Energy Intake; Fructosamine; Fructose; Glucose; Glycation End Products, Advanced; Lysine; Male; Rats; Rats, Inbred F344; Skin; Starch | 2000 |
Arginine enhances In vivo immune responses in young, adult and aged mice.
Topics: Aging; Animals; Arginine; Body Weight; Dietary Supplements; Hypersensitivity, Delayed; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Organ Size | 2000 |
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Child; Child, Preschool; Collagen; Collagenases; Cross-Linking Reagents; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Skin; Spectrometry, Fluorescence | 2000 |
Decrease of neuronal nitric oxide synthase in the cerebellum of aged rats.
Topics: Aging; Animals; Arginine; Blotting, Northern; Blotting, Western; Cerebellum; Citrulline; Densitometry; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde-3-Phosphate Dehydrogenases; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; RNA, Messenger | 2000 |
Acceleration of pubertal development following central blockade of the Y1 subtype of neuropeptide Y receptors.
Topics: Aging; Animals; Arginine; Body Weight; Female; Hypothalamus; Luteinizing Hormone; Neuropeptide Y; Pituitary Gland; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Sexual Maturation; Vagina; Weight Gain | 2000 |
Age-related variations in the neuroendocrine control, more than impaired receptor sensitivity, cause the reduction in the GH-releasing activity of GHRPs in human aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Dose-Response Relationship, Drug; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Male; Neurosecretory Systems; Oligopeptides | 1998 |
Growth hormone deficiency in elderly patients with hypothalamo-pituitary tumors.
Topics: Aged; Aging; Arginine; Body Composition; Bone Density; Case-Control Studies; Collagen; Collagen Type I; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypothalamic Neoplasms; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Middle Aged; Osteocalcin; Peptides; Pituitary Neoplasms | 1998 |
Upregulation of the nitric oxide-cGMP pathway in aged myocardium: physiological response to l-arginine.
Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Female; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Up-Regulation | 2001 |
Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Substitution; Arginine; Arteriosclerosis; Coronary Artery Disease; Cysteine; Finland; Gene Frequency; Genotype; Haplotypes; Humans; Infant, Newborn; Leucine; Longevity; Mexico; Middle Aged; Phenylalanine; Polymorphism, Genetic; Werner Syndrome | 2000 |
Isoleucine imbalance using selected mixtures of imbalancing amino acids in diets of the broiler chick.
Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Composition; Chickens; Diet; Dietary Proteins; Eating; Isoleucine; Lysine; Male; Nutritional Requirements; Regression Analysis; Weight Gain | 2000 |
Contrasting effects of L-arginine on insulin-mediated blood flow and glucose disposal in the elderly.
Topics: Adult; Aged; Aging; Anthropometry; Arginine; Blood Flow Velocity; Blood Glucose; Blood Pressure; Electric Conductivity; Female; Glucose Clamp Technique; Heart Rate; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Nitric Oxide; Vasodilation | 2001 |
Modest overexpression of neuropeptide Y in the brain leads to obesity after high-sucrose feeding.
Topics: Aging; Animals; Arginine; Brain; Cyclohexanes; Dietary Sucrose; Energy Intake; Homozygote; Humans; Mice; Mice, Knockout; Mice, Transgenic; Neuropeptide Y; Obesity; Phenotype; Promoter Regions, Genetic; Receptors, Neuropeptide Y; Reference Values; Thy-1 Antigens; Xanthenes | 2001 |
Endogenous nitric oxide-mediated relaxation and nitrinergic innervation in the rabbit prostate: the changes with aging.
Topics: Aging; Aminoquinolines; Animals; Arginine; Atropine; Electric Stimulation; Guanethidine; Histocytochemistry; In Vitro Techniques; Indomethacin; Male; Muscle Tonus; Muscle, Smooth; NADPH Dehydrogenase; Nerve Fibers; Nitric Oxide; Organ Size; Propranolol; Prostate; Rabbits; Tetrodotoxin; Tissue Distribution | 2001 |
Accelerated tissue aging and increased oxidative stress in broiler chickens fed allopurinol.
Topics: Aging; Allopurinol; Animals; Antimetabolites; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Glycation End Products, Advanced; Glycosylation; Hemin; Luminescent Measurements; Lysine; Muscle, Skeletal; Oxidative Stress; Skin; Uric Acid | 2001 |
Elevated serum endogenous inhibitor of nitric oxide synthase and endothelial dysfunction in aged rats.
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Kidney; Male; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2001 |
Reduction in asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in the cerebrospinal fluid during aging and in patients with Alzheimer's disease.
Topics: Aged; Aging; Alzheimer Disease; Arginine; Brain; Female; Humans; Male; Middle Aged; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress | 2001 |
Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.
Topics: Adrenergic beta-Agonists; Age Factors; Aging; Animals; Arginine; Blotting, Western; Citrulline; Cyclic AMP; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunity; Interferon-gamma; Isoproterenol; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysine; Nitric Oxide; Rats; Rats, Wistar; Sepsis; Signal Transduction; Up-Regulation | 2001 |
Maturation-dependent neointima formation in fowl aorta.
Topics: Actins; Aging; Animals; Aorta, Abdominal; Arginine; Asparagine; Blood Pressure; Chickens; Cholesterol; Female; Hyperplasia; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nitric Oxide; Ornithine; Phenylalanine; Tunica Intima | 2001 |
Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chondroitin Sulfate Proteoglycans; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Lectins, C-Type; Lysine; Middle Aged; Osteoarthritis; Proteoglycans | 2001 |
Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: the role of advanced glycation end products.
Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Arginine; Arthritis, Rheumatoid; Cartilage, Articular; Cattle; Chromatography, High Pressure Liquid; Glycosaminoglycans; Humans; In Vitro Techniques; Knee Joint; Lysine; Matrix Metalloproteinases; Middle Aged; Osteoarthritis, Knee; Phenylmercuric Acetate; Ribose; Synovial Fluid | 2001 |
Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice.
Topics: Aging; Animals; Arginine; Brain Chemistry; Creatinine; Glycine; Guanidines; Homoarginine; Humans; Hypertrophy; Kidney; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Succinates; Urea | 2001 |
Isolated systolic hypertension in elderly WKY is reversed with L-arginine and ACE inhibition.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Collagen; Coronary Circulation; Hemodynamics; Hypertension; Kidney; Male; Myocardium; Organ Size; Rats; Rats, Inbred WKY; Regional Blood Flow; Vascular Resistance; Ventricular Function, Left | 2001 |
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
Topics: Adult; Aging; Arginine; Cartilage, Articular; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Lysine; Osteoarthritis; Pyruvaldehyde; Regression Analysis; Ribose; Stress, Mechanical; Tetroses | 2002 |
[Levels of mature cross-links and advanced glycation end product cross-links in human vitreous].
Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cross-Linking Reagents; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Vitreous Body | 2002 |
Long-term high-fat feeding leads to severe insulin resistance but not diabetes in Wistar rats.
Topics: Acyl Coenzyme A; Aging; Animals; Arginine; Blood Glucose; Body Composition; Diabetes Mellitus; Dietary Fats; Fasting; Genetic Predisposition to Disease; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Glycogen; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Rats; Rats, Wistar; Time Factors; Triglycerides; Weight Gain | 2002 |
The 'intestinal-renal' arginine biosynthetic axis in the aging rat.
Topics: Aging; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Cerebellum; Citrulline; Female; Glutaminase; Intestine, Small; Kidney; Kidney Cortex; Male; Ornithine Carbamoyltransferase; Rats; Rats, Sprague-Dawley | 2002 |
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aging; Animals; Arginine; Arterioles; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Coronary Vessels; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Immunohistochemistry; In Vitro Techniques; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Phenotype; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tyrosine; Vasodilation; Xanthine Oxidase | 2002 |
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alleles; Amino Acid Substitution; Arginine; Aryldialkylphosphatase; Esterases; Female; Gene Frequency; Humans; Longevity; Male | 2002 |
Effect of age on bone mineral density and the serum concentration of endogenous nitric oxide synthase inhibitors in rats.
Topics: Absorptiometry, Photon; Aging; Animals; Arginine; Bone and Bones; Bone Density; Enzyme Inhibitors; Male; Malondialdehyde; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 2002 |
[Investigations on the plasm amino acids of old patients with rheumatoid arthritis (author's transl)].
Topics: Aged; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Chromatography, Ion Exchange; Cystathionine; Humans; Methylhistidines; Middle Aged; Threonine; Tryptophan | 1977 |
Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Biological Transport, Active; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Methionine; Phenylalanine; Rats; Valine | 1979 |
Age related activity changes in arginine phosphokinase in the house fly, Musca domestic+ L.
Topics: Aging; Animals; Arginine; Cytoplasm; Female; Flight, Animal; Houseflies; Male; Phosphotransferases; Sex Factors | 1975 |
Age-dependent arginine phosphokinase activity changes in male vestigial and wild-type Drosophila melanogaster.
Topics: Aging; Animals; Arginine; Drosophila melanogaster; Female; Flight, Animal; Male; Muscles; Mutation; Phosphotransferases | 1975 |
Effect of aging on free amino acids and electrolytes in leg skeletal muscle.
Topics: Aged; Aging; Alanine; Amino Acids; Arginine; Citrulline; Electrolytes; Histidine; Humans; Leg; Male; Middle Aged; Muscles; Water | 1979 |
Orotic aciduria and increased nitrogen catabolism in rats.
Topics: Aging; Animals; Arginine; Dietary Proteins; Male; Nitrogen; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Rats; Starvation | 1979 |
Effect of growth & differentiation on distribution of arginase & arginine in rat tissues.
Topics: Aging; Animals; Arginase; Arginine; Growth; Liver Neoplasms, Experimental; Liver Regeneration; Male; Rats | 1979 |
Ontogenetic changes in the content of methylated amino acids in rodent skeletal muscle.
Topics: Aging; Animals; Arginine; Cricetinae; Histidine; Lysine; Male; Methylation; Methylhistidines; Mice; Muscle Development; Muscles; Myosins; Rats | 1977 |
[Raised glucagon levels of the blood induced by arginine: relation to blood sugar, blood insulin and STH in aged non-diabetics and diabetics].
Topics: Adult; Age Factors; Aged; Aging; Arginine; Blood Glucose; Diabetes Mellitus; Glucagon; Growth Hormone; Humans; Insulin | 1978 |
Orotic aciduria in the female rat and its relation to dietary arginine.
Topics: Aging; Ammonia; Animals; Arginine; Birth Weight; Body Weight; Citrates; Female; Litter Size; Orotic Acid; Pregnancy; Pregnancy Complications; Rats; Species Specificity; Urea | 1978 |
[Effects of ageing on arginine-induced secretion of insulin (author's transl)].
Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Female; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged | 1978 |
Insulin and growth hormone in lean and obese pigs.
Topics: Aging; Animals; Arginine; Blood Glucose; Fasting; Glucose; Growth Hormone; Insulin; Obesity; Swine | 1977 |
Insect flight muscle: maturation and senescence.
Topics: Age Factors; Aging; Animals; Arginine; Female; Flight, Animal; Glycogen; Insecta; Male; Mitochondria, Muscle; Muscles; Oxidoreductases; Sex Factors | 1976 |
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Piperazines; Potassium Chloride; Protein Kinase C; Rabbits | 1992 |
Possible mechanisms of age-associated reduction of vascular relaxation caused by atrial natriuretic peptide.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinones; Rats; Rats, Inbred Strains | 1992 |
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar | 1992 |
Developmental changes in endothelium-dependent pulmonary vasodilatation in pigs.
Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Masoprocol; Microscopy, Electron; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; omega-N-Methylarginine; Pulmonary Artery; Swine; Vasodilation | 1992 |
A neuroendocrinological approach to evidence an impairment of central cholinergic function in aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Insulin-Like Growth Factor I; Male; Pituitary Gland; Pyridostigmine Bromide | 1992 |
[Influences of hypercholesterolemia on the vessel function of isolated rat thoracic aorta].
Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Body Weight; Cholesterol, Dietary; Endothelium, Vascular; Hypercholesterolemia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; omega-N-Methylarginine; Phenylephrine; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Vasoconstriction | 1992 |
Pattern of thyrotropin-releasing hormone secretion from the adult and neonatal rat pancreas: comparison with insulin secretion.
Topics: Aging; Animals; Animals, Newborn; Arginine; Cells, Cultured; Chromatography, Gel; Female; Gene Expression; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Pregnancy; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1992 |
GH response to GHRH, insulin, clonidine and arginine after GHRH pretreatment in children.
Topics: Adolescent; Aging; Arginine; Child; Child, Preschool; Clonidine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin; Male | 1992 |
Exercise training delineates the importance of B-cell dysfunction to the glucose intolerance of human aging.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bicycling; Blood Glucose; Exercise; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Running | 1992 |
Impairment of L-arginine metabolism in spontaneously hypertensive rats.
Topics: Aging; Animals; Arginine; Hypertension; Immersion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stress, Physiological | 1992 |
Fluorophores from aging human articular cartilage.
Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Female; Humans; Lysine; Male; Microbial Collagenase; Middle Aged; Solubility; Spectrometry, Fluorescence | 1991 |
Effects of different regimens of dietary restriction on the age-related decline in insulin secretory response of isolated rat pancreatic islets.
Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Diet, Reducing; Energy Intake; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Arginine-deficient diets alter plasma and tissue amino acids in young and aged rats.
Topics: Aging; Amino Acids; Ammonia; Animals; Arginine; Diet; Liver; Male; Orotic Acid; Rats; Rats, Inbred Strains; Spleen | 1991 |
The effects of overeating on insulin secretion in normal mice.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Cacao; Diet; Feeding and Eating Disorders; Glucose; Glucose Tolerance Test; Glycated Hemoglobin; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred ICR; Perfusion; Reference Values | 1991 |
Dietary arginine supplementation does not enhance lymphocyte proliferation or interleukin-2 production in young and aged rats.
Topics: Aging; Alanine; Animals; Arginine; Body Weight; Citrulline; Concanavalin A; Diet; Glutamine; Interleukin-2; Lymphocyte Activation; Male; Organ Size; Ornithine; Phytohemagglutinins; Pokeweed Mitogens; Rats; Rats, Inbred F344; Spleen | 1991 |
Alterations of biochemical and biomechanical properties of rat tail tendons caused by non-enzymatic glycation and their inhibition by dibasic amino acids arginine and lysine.
Topics: Aging; Animals; Arginine; Fructosamine; Glucose; Glycosylation; Hexosamines; In Vitro Techniques; Kinetics; Lysine; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Stress, Mechanical; Tail; Tendons | 1991 |
NG-monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats.
Topics: Acetylcholine; Aging; Animals; Arginine; Blood Pressure; Heart Rate; Injections, Intravenous; Male; omega-N-Methylarginine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity | 1991 |
Development of pyrroline-5-carboxylate synthase and N-acetylglutamate synthase and their changes in lactation and aging.
Topics: Acetyltransferases; Aging; Amino-Acid N-Acetyltransferase; Animals; Arginine; Female; Intestine, Small; Kinetics; Lactation; Liver; Ornithine-Oxo-Acid Transaminase; Pregnancy; Rats; Rats, Inbred Strains; Urea | 1991 |
High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis.
Topics: Adult; Aged; Aging; Animals; Arginine; Ascorbic Acid; Cataract; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Crystallins; Humans; Hydrolysis; Lens, Crystalline; Lysine; Models, Biological; Molecular Weight; Pigmentation; Reference Values | 1991 |
Age-related decrease in plasma growth hormone: response to growth hormone-releasing hormone, arginine, and L-dopa in obesity.
Topics: Adolescent; Adult; Aged; Aging; Arginine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Levodopa; Male; Middle Aged; Obesity | 1991 |
Lifelong sequential changes in glucose tolerance and insulin secretion in genetically obese Zucker rats (fa/fa) fed a diabetogenic diet.
Topics: Aging; Animals; Arginine; Blood Glucose; Diabetes Mellitus; Diet; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Longitudinal Studies; Obesity; Rats; Rats, Zucker | 1991 |
Gradual delay in glucose-induced first phase insulin secretion by the pancreatic islets of 7 week-, 6 month-, and 1 year-old rats.
Topics: Aging; Animals; Arginine; Calcium; Culture Techniques; Cytosol; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; In Vitro Techniques; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Reference Values | 1991 |
Maturational changes in endothelium-derived relaxing factor activity of ovine pulmonary arteries in vitro.
Topics: Acetylcholine; Adenosine Diphosphate; Aging; Animals; Animals, Newborn; Arginine; Female; Gestational Age; In Vitro Techniques; Kinetics; Muscle Development; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Pregnancy; Pulmonary Artery; Sheep; Vasodilation; Vasodilator Agents | 1991 |
Growth hormone (GH) responsiveness to combined administration of arginine and GH-releasing hormone does not vary with age in man.
Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Kinetics; Male | 1990 |
[The effect of intravenous administration of arginine and glycine on the blood plasma content of glucose, insulin, free fatty acids and total alpha-amino-N-compounds in lambs of different ages].
Topics: Aging; Animals; Arginine; Blood Glucose; Fatty Acids, Nonesterified; Glycine; Insulin; Sheep | 1990 |
Activation of endothelial L-arginine pathway in resistance arteries. Effect of age and hypertension.
Topics: Acetylcholine; Aging; Animals; Arginine; Endothelium, Vascular; Hypertension; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction | 1990 |
Implication of lysine residues in the loss of enzymatic activity in rat liver 6-phosphogluconate dehydrogenase found in aging.
Topics: Aging; Animals; Arginine; Ascorbic Acid; Chemical Phenomena; Chemistry, Physical; Histidine; Immunosorbent Techniques; Liver; Lysine; Methionine; Molecular Weight; Oxidation-Reduction; Peptide Fragments; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1989 |
Insulin, growth hormone, glucose, and fatty acids in gilts selected for rapid vs. slow growth rate.
Topics: Aging; Animals; Arginine; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose; Growth Hormone; Growth Hormone-Releasing Hormone; Insulin; Species Specificity; Swine | 1989 |
[Immunoreactive 7B2 concentrations in plasma and cerebrospinal fluid in pathophysiological conditions and the responses to oral glucose load, intravenous LH-RH, TRH and arginine infusion].
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Cerebrovascular Disorders; Child; Child, Preschool; Female; Fetal Blood; Glucose; Gonadotropin-Releasing Hormone; Humans; Infant; Infusions, Intravenous; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Nerve Tissue Proteins; Neuroendocrine Secretory Protein 7B2; Pituitary Hormones; Pregnancy; Thyrotropin-Releasing Hormone | 1989 |
Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process.
Topics: Aging; Animals; Arginine; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dura Mater; Extracellular Matrix; Hexoses; Humans; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Organ Specificity; Pentoses; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 1989 |
Plasma glucagon-immunoreactive components in early life in dogs.
Topics: Aging; Animals; Animals, Newborn; Arginine; Dogs; Glucagon; Glucagon-Like Peptides; Insulin; Peptides; Radioimmunoassay; Somatostatin | 1985 |
Adenylate energy charge, arginine phosphate and ATPase activity in juvenile Homarus americanus during the molt cycle.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Arginine; Energy Metabolism; Gills; Liver; Muscle Development; Nephropidae; Organ Specificity; Pancreas; Sodium-Potassium-Exchanging ATPase | 1985 |
[The effect of synthetic human pancreatic growth hormone-releasing factor (hpGRF-44) on serum growth hormone response in normal and obese subjects].
Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Female; Follicle Stimulating Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hydrocortisone; Insulin; Luteinizing Hormone; Male; Middle Aged; Obesity; Peptide Fragments; Prolactin; Thyrotropin | 1986 |
Recovery of age-related decline of thymic endocrine activity and PHA response by lysin-arginine combination.
Topics: Aging; Amino Acids; Animals; Arginine; Cytotoxicity Tests, Immunologic; Lysine; Male; Mice; Mice, Inbred BALB C; Phytohemagglutinins; Thymic Factor, Circulating; Thymus Gland; Thymus Hormones | 1986 |
Possible involvement of histidine residues in the loss of enzymatic activity of rat liver malic enzyme during aging.
Topics: Aging; Animals; Arginine; Histidine; Kinetics; Liver; Lysine; Malate Dehydrogenase; Methionine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds | 1988 |
Effect of age on the insulin secretory response of perfused rat pancreas to arginine and tolbutamide.
Topics: Aging; Animals; Arginine; Body Weight; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Size; Perfusion; Radioimmunoassay; Rats; Tolbutamide | 1987 |
In vitro response to mitogens and antigens in elderly and post-cytotoxic patients can be modified by a new hypoxanthine derivative (PCF-39).
Topics: Aged; Aging; Antineoplastic Agents; Arginine; Diabetes Mellitus, Type 2; Humans; Hypoxanthines; Immunity, Cellular; Lymphocyte Activation; Melanoma; Phytohemagglutinins | 1987 |
Age-related differences in the incorporation of 3H-arginine into vasopressin in Fischer 344 rats.
Topics: Aging; Animals; Arginine; Arginine Vasopressin; Biological Transport, Active; Hypothalamus; Kinetics; Male; Pituitary Gland, Posterior; Rats; Rats, Inbred F344 | 1987 |
Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased beta-cell function.
Topics: Adipose Tissue; Adolescent; Adult; Aged; Aging; Arginine; Blood Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Resistance; Islets of Langerhans; Kinetics; Male; Middle Aged | 1985 |
Carbohydrate intolerance in gonadal dysgenesis: evidence for insulin resistance and hyperglucagonemia.
Topics: Adolescent; Adult; Aging; Arginine; Blood Glucose; Body Weight; Child; Glucagon; Glucose Tolerance Test; Gonadal Dysgenesis; Growth Hormone; Humans; Insulin; Insulin Resistance; Malabsorption Syndromes; Male; Obesity; Tolbutamide | 1985 |
Analysis of immunoreactive insulins in man in relation to the effects of aging.
Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Blood Proteins; Fasting; Humans; Immunoelectrophoresis; Insulin; Islets of Langerhans; Middle Aged; Proinsulin | 1985 |
Ontogeny modifies manifestations of cystinuria genes: implications for counseling.
Topics: Aging; Amino Acids; Arginine; Cystinuria; Follow-Up Studies; Genetic Counseling; Genotype; Humans; Infant, Newborn; Lysine; Ornithine; Phenotype; Quebec | 1985 |
Effect of arginine-free diet on ammonia metabolism in young and adult ferrets.
Topics: Aging; Ammonia; Animals; Arginine; Benzoates; Benzoic Acid; Brain; Brain Diseases; Diet; Ferrets; Male | 1986 |
Nutritional and metabolic responses to arginine deficiency in carnivores.
Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Arginine; Carnivora; Cats; Citrulline; Dogs; Glutamine; Intestinal Mucosa; Kidney; Liver; Muscles; Nutritional Requirements; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Rats; Species Specificity; Urea | 1985 |
Methylation of myelin basic protein by enzymes from rat brain.
Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration | 1974 |
Biochemical aspects of the aging of the sea mussel Mytilus gallo-provincialis.
Topics: Adenosine Triphosphatases; Aging; Animals; Arginine; Bivalvia; Chick Embryo; Muscles | 1974 |
Insulin secretion during development: response of isolated pancreatic islets of fetal, newborn and adult rats to theophylline and arginine.
Topics: Aging; Animals; Animals, Newborn; Antigens; Arginine; Female; Fetus; Glucose; Immunoassay; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Microbial Collagenase; Rats; Stimulation, Chemical; Theophylline | 1972 |
Hydrolytic enzyme activities in the developing chick central and peripheral nervous systems.
Topics: Aging; Aminopeptidases; Animals; Arginine; Brain; Chick Embryo; Chickens; Glutamates; Leucyl Aminopeptidase; Lysine; Naphthols; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Sciatic Nerve; Time Factors | 1974 |
On the water economy of Israel amphibians; the anurans.
Topics: Aging; Animals; Anura; Arginine; Bufonidae; Kinetics; Oxytocin; Ranidae; Skin; Sweating; Temperature; Urinary Bladder; Vasotocin; Water; Water Loss, Insensible; Xenopus | 1971 |
Fetal development: the effects of maturation on in vitro protein synthesis by mouse brain tissue.
Topics: Aging; Animals; Animals, Newborn; Arginine; Brain; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Deoxycholic Acid; Female; Fetus; Gestational Age; In Vitro Techniques; Magnesium; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phenylalanine; Polyribosomes; Pregnancy; Time Factors | 1974 |
Further data on the age-dependent intestinal absorption of dibasic amino acids.
Topics: Aging; Amino Acids; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestines; Lysine; Organ Size; Rats | 1974 |
[Proceedings: Effects of aging on arginine induction of insulin secretion].
Topics: Adult; Aged; Aging; Arginine; Female; Humans; Insulin; Male; Middle Aged | 1974 |
Changes in transfer RNAs and aminoacyl-tRNA synthetases during sea urchin development.
Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Arginine; Carbon Isotopes; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Embryo, Nonmammalian; Female; Fertilization; Leucine; Lysine; Ovum; RNA, Transfer; Saccharomyces cerevisiae; Sea Urchins; Serine; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1973 |
Effect of age on growth hormone secretion in man.
Topics: Adipose Tissue; Adult; Aged; Aging; Arginine; Blood Glucose; Body Composition; Fasting; Glucose; Growth Hormone; Humans; Male; Middle Aged; Potassium Isotopes | 1973 |
Synthesis and degradation of chicken liver xanthine dehydrogenase during development.
Topics: Aging; Alcohol Oxidoreductases; Animals; Arginine; Carbon Isotopes; Chick Embryo; Chickens; Chromatography, Ion Exchange; Electrophoresis, Disc; Kinetics; Liver; Methods; Valine | 1973 |
Gluconeogenesis in the newborn rat: the substrates and their quantitative significance.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginase; Arginine; Dietary Fats; Female; Gluconeogenesis; Glycerol; Glycogen; L-Lactate Dehydrogenase; Lactates; Lactation; Ligases; Lipid Metabolism; Liver; Mitochondria, Liver; Pregnancy; Pyruvates; Rats; Succinates; Urea | 1973 |
Free amino acids in developing rat retina.
Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine | 1974 |
[Aortic elastin and its variations during senescence and arteriosclerosis].
Topics: Aging; Amino Acids; Animals; Aorta; Arginine; Arteriosclerosis; Aspartic Acid; Cattle; Elastin; Glutamates; Lysine; Rabbits | 1970 |
Age-related alterations in the structure of nucleoprotein. IV. Changes in the compoistion of whole histone from rat liver.
Topics: Age Factors; Aging; Animals; Arginine; DNA; Edetic Acid; Female; Histones; Immunodiffusion; Liver; Lysine; Methods; Nucleoproteins; Rats; Temperature | 1969 |
Biochemical studies on the aging of rat tail tendon.
Topics: Aging; Animals; Arginine; Calcium Chloride; Collagen; Fucose; Galactose; Glucose; Glycoproteins; Glycosides; Hexosamines; Hexoses; Hydroxyproline; Lysine; Mannose; Proteins; Rats; Tail; Tendons; Time Factors; Xylose | 1971 |
Preparation of two antigens of human liver isoenzymes of alkaline phosphatase.
Topics: Aging; Alkaline Phosphatase; Antibody Formation; Antigens; Arginine; Chromatography, Gel; Depression, Chemical; Humans; Immune Sera; Immunoelectrophoresis; Isoenzymes; Liver; Magnesium; Phenylalanine; Stimulation, Chemical | 1971 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
The effect of catechol amines on free amino acids in rat heart and other organs.
Topics: Aging; Alanine; Amino Acids; Animals; Arginine; Epinephrine; Female; Glutamates; Glutamine; Heart; Liver; Metabolism; Myocardium; Norepinephrine; Ornithine; Rats; Reserpine; Time Factors | 1969 |
The biosynthesis of protamine in trout testis. II. Polysome patterns and protein synthetic activities during testis maturation.
Topics: Aging; Animals; Arginine; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; Liver; Lysine; Magnesium; Male; Protamines; Ribonucleases; Ribosomes; Salmonidae; Seasons; Testis; Ultracentrifugation | 1970 |
Estrogen-induced variation of lysine transfer ribonucleic acid isoacceptors in chicken liver.
Topics: Aging; Albumins; Animals; Arginine; Chickens; Chromatography; Detergents; Diethylstilbestrol | 1970 |
Intestinal transfer of l-arginine in relation to age.
Topics: Aging; Animals; Arginine; Carbon Isotopes; Female; Intestinal Absorption; Intestine, Small; Rats | 1970 |
Metabolic changes in the tissues of young and old mice. Oxygen consumption with different substrates.
Topics: Aging; Animals; Arginine; Brain; Glutamates; Kidney; Malates; Manometry; Mice; Myocardium; Oxygen Consumption | 1968 |
Studies on the histones and DNA of calf and old cow thymus.
Topics: Aging; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Cesium; Chromosomes; DNA; Histocytochemistry; Histones; Lysine; Molecular Biology; Spectrophotometry; Thymus Gland | 1968 |