arginine and Aging

arginine has been researched along with Aging in 482 studies

Research

Studies (482)

TimeframeStudies, this research(%)All Research%
pre-199072 (14.94)18.7374
1990's170 (35.27)18.2507
2000's128 (26.56)29.6817
2010's93 (19.29)24.3611
2020's19 (3.94)2.80

Authors

AuthorsStudies
Hu, J; Ji, L; Johnston, LJ; Liu, C; Ma, X; Zhang, X; Zhao, Y1
Arabzadeh, E; Feizolahi, F; Hatami Nasab, Z; Zargani, M1
Arabzadeh, E; Feizolahi, F; Mazaheri Tirani, Z; Rahimi, A; Zargani, M1
Baumann, A; Bergheim, I; Brandt, A; Camarinha-Silva, A; Franzke, B; Hernández-Arriaga, A; Jung, F; Nier, A; Rajcic, D; Schmeer, C; Staltner, R; Wagner, KH; Wessner, B; Witte, OW1
Andtbacka, RHI; Hyngstrom, JR; Kwon, OS; Noh, SG; Park, SH; Richardson, RS1
Arc-Chagnaud, C; De la Rosa, A; Guerra-Ojeda, S; Mauricio, MD; San-Miguel, T; Serna, E; Valls, A; Verdú, D; Viña, J1
Beletti, ME; Butolo, EAF; Butolo, JEG; Oliveira, LBT; Reis, RS; Travençolo, BAN1
Bijsmans, ES; Biourge, VC; Chang, YM; Elliott, J; Jepson, RE; Sargent, HJ1
Cifù, A; Curcio, F; Domenis, R; Fabris, M; Garbo, R; Giacomello, R; Gigli, GL; Janes, F; Nilo, A; Pessa, ME; Sanvilli, N; Valente, M1
Darband, SG; Kaviani, M; Majidinia, M; Mobaraki, K; Sadighparvar, S; Yousefi, B1
Burrin, DG; Didelija, IC; Marini, JC; Mohammad, MA; Stoll, B; Wang, X1
Choisy, C; Cynober, L; De Bandt, JP; Le Plenier, S; Nakib, S; Neveux, N; Raynaud-Simon, A; Sarfati, G; Tennoune, N; Ventura, G1
Hayashi, T1
Figueroa, A; Gonzales, JU; Jaime, SJ; Moinard, C; Morita, M1
Arakawa, S; Hayashi, H; Ikeda, R; Kayama, T; Kurosaka, D; Marumo, K; Nagai, R; Ohno, RI; Saito, M; Suzuki, R1
Engdahl, C; Farman, HH; Gustafsson, KL; Henning, P; Lagerquist, MK; Lawenius, L; Lionikaite, V; Movérare-Skrtic, S; Nilsson, KH; Ohlsson, C1
Ikegami, S; Kato, H; Nakamura, Y; Nakano, M; Sakai, N; Suzuki, T; Takahashi, J; Tokida, R; Uehara, M1
Castro-Diehl, C; Ehrbar, R; Obas, V; Oh, A; Vasan, RS; Xanthakis, V1
Adamski, J; Artati, A; Blaauw, B; Dyar, KA; Huber, S; Möller, G; Tokarz, J; Zeigerer, A1
Nakamura, Y; Unno, K1
Chertok, AG; Chertok, VM; Kotsyuba, AE1
Amancio-Dos-Santos, A; Duda-de-Oliveira, D; Falcão, ACSM; Germano, PCPDS; Guedes, RCA; Maia, LMSS1
Romanov, GA; Sukhoverov, VS1
Cao, J; Lei, T; Liu, S; Lu, Z; Shi, L; Wang, H; Zhao, C1
Bernstein, HG; Laube, G1
Fujitsuka, N; Hattori, T; Mogami, S; Yamada, C1
Jönsson, TJ; Kennedy, AD; Milgram, NW; Pan, Y1
Damanhuri, HA; Hamezah, HS; Jing, Y; Liu, P; Mazlan, M; Taridi, NM; Wan Ngah, WZ; Zhang, H1
Clay Bunn, R; Creecy, A; Nyman, JS; Unal, M; Uppuganti, S; Voziyan, P1
Buchalla, W; Grillmeier, I; Hiller, KA; Neubauer, C; Schmalz, G1
Arnold, P; Bautmans, I; Buyl, R; Gorus, E; Njemini, R; Pool-Goudzwaard, A; Vantieghem, S1
Esmaeili, M; Gilani, N; Haghshenas, R1
Brodmann, M; Gary, T; Hackl, G; Hafner, F; Jud, P; Meinitzer, A; Seinost, G; Verheyen, N1
Amiya, Y; Fujii, H; Katayama, S; Maebuchi, M; Matsui, T; Mitani, T; Nakamura, S; Shimizu, A; Tanaka, M; Tanaka, S1
Antal, M; Contreras, GA; Dormann, D; Fekecs, Z; Guo, X; Hickman, J; Hortobagyi, T; Horvath, A; Jiang, LL; Karolyi, K; Keresztessy, Z; Kiss, G; Kolostyak, Z; Nagy, L; Nógrádi, A; Pajer, K; Pap, A; Papp, Z; Patsalos, A; Reho, B; Sari, Z; Sieler, T; Simandi, Z; Vámosi, G; Xu, H1
García-Villanova, B; Guerra-Hernández, E; Hougen, HP; Márquez-Ruiz, AB; Rufián-Henares, JÁ; Valenzuela, A1
Saito, M; Satake, Y; Takahashi, K; Takai, S1
Kövamees, O; Mahdi, A; Pernow, J1
Becker, J; Eickhoff, SB; Mahlke, NS; Reckert, A; Ritz-Timme, S1
Endo, H; Kajitani, S; Kanazawa, M; Kondo, M; Nakamura, A; Nozaki, E; Sato, K1
Atawia, RT; Bragg, RT; Caldwell, RW; Fulzele, S; Hamrick, M; Isales, C; Lee, B; Mendhe, B; Pandya, B; Pandya, CD; Toque, HA1
Imai, T; Kashiwabara, S; Saito, M; Shiraki, M; Tanaka, S1
Carru, C; Mangoni, AA; McEvoy, M; Rodionov, RN; Sotgia, S; Zinellu, A1
Baamonde-Laborda, E; Gonzalez-Cabrera, F; Oliva-Damaso, E; Oliva-Damaso, N; Payan, J; Rodriguez-Esparragon, F; Rodriguez-Perez, JC; Santana-Estupiñan, R1
Bouras, G; Chatzis, G; Cleman, MW; Deftereos, S; Giannopoulos, G; Stefanadis, C; Tousoulis, D; Tsounis, D1
Karim, L; Sroga, GE; Tang, SY; Vashishth, D1
Micans, P1
Basso, A; Costarelli, L; Giacconi, R; Lattanzio, F; Malavolta, M; Mocchegiani, E; Piacenza, F1
Collie, ND; Fleete, MS; Jing, Y; Liu, P; Zhang, H1
Chlebda-Sieragowska, E; Fereniec-Gołębiewska, L; Kwiatkowska, J; Merwid-Ląd, A; Pieśniewska, M; Sozański, T; Szeląg, A; Szuba, A; Trocha, M1
Alcantara, R; Baltgalvis, KA; Claypool, MD; Friera, AM; Godinez, G; Goff, D; Gururaja, T; Hansen, D; Hitoshi, Y; Jenkins, Y; Kinsella, TM; Lang, W; Lau, D; Li, W; Li, Y; Markovtsov, V; McCaughey, K; McLaughlin, J; Nguyen, H; Pan, A; Park, G; Payan, DG; Shaw, SJ; Singh, BK; Singh, R; Smith, IJ; Sun, TQ; Uy, G; White, K1
Asai, K; Hirata, K; Kanazawa, H; Kyoh, S; Tochino, Y1
Benno, Y; Kakeyama, M; Kibe, R; Kitada, Y; Kurihara, S; Matsumoto, M; Muramatsu, K; Nakamura, A; Ooga, T; Sakai, Y; Sawaki, E; Suzuki, H; Yamashita, A1
Abraham, WC; Collie, ND; Curtis, MA; Faull, RL; Fleete, MS; Jing, Y; Liu, P; Waldvogel, HJ; Zhang, H1
Bayatli, N; Gur, S; Kaya, E; Un, O; Yilmaz, D1
Chan, WP; Chirkov, YY; Horowitz, JD; Ngo, DT; Sverdlov, AL1
Kurumatani, N; Obayashi, K; Saeki, K1
Dhondt, A; Eloot, S; Glorieux, G; Liabeuf, S; Massy, Z; Neirynck, N; Rroji, M; Van Biesen, W; Vandennoortgate, N; Vanholder, R1
Adams, V; Erbs, S; Gielen, S; Hambrecht, R; Höllriegel, R; Kirsch, K; Linke, A; Lurz, P; Mangner, N; Möbius-Winkler, S; Rabald, K; Sandri, M; Schuler, G; Teupser, D; Thiery, J; Viehmann, M1
Akhlaghi, A; Esmaeile Neia, L; Lotfi, L; Sharideh, H; Zaghari, M; Zhandi, M1
Calhoun, D; Dudenbostel, T; Ellis, AC; Gower, B; Patterson, M1
Ashor, A; Brandt, K; Lara, J; Mathers, JC; Ogbonmwan, I; Oggioni, C; Qadir, O; Siervo, M; Zheng, D1
Marumo, K; Saito, M1
Ishigami, A; Machii, H; Miura, S; Owada, T; Saitoh, S; Takeishi, Y; Yamada, S; Yamauchi, H1
Bowdish, DM; Fei, F; Lee, KM; McCarry, BE1
Basili, S; Campesi, I; Carru, C; Cherchi, S; Franconi, F; Occhioni, S; Tonolo, G; Zinellu, A1
Bank, RA; Hooymans, JM; Los, LI; van Deemter, M; Vehof, J1
Friedrich, MG; Hancock, SE; Raftery, MJ; Truscott, RJ1
Bendixen, C; Farajzadeh, L; Kristensen, KK; Larsen, K; Momeni, J1
Dorca, J; Escobar, I; Llatjos, R; Machahua, C; Molina-Molina, M; Montes-Worboys, A; Vicens-Zygmunt, V1
Bobe, G; Hall, JA; Jewell, DE; Obare, E; Panickar, KS; Yerramilli, M1
Chen, Z; Cui, K; Liu, J; Luan, Y; Rao, K; Tang, Z; Wang, D; Wang, S; Wang, T1
Demougeot, C; Guglielmetti, AS; Marie, C; Martin, H; Moretto, J; Prigent-Tessier, A; Tournier-Nappey, M1
Abe, Y; Arai, Y; Hirata, T; Ohkuma, K; Takayama, M; Takebayashi, T1
Gongora, E; Nair, N1
Collie, ND; Gupta, N; Jing, Y; Liu, P; Smith, PF; Zhang, H1
Blanc, RS; Richard, S1
Chakraborti, A; Gulati, K; Ray, A1
Berkowitz, DE; Christianson, DW; Nyhan, D; Santhanam, L1
Frazão, MF; Guedes, RC; Silva de Seixas Maia, LM1
Chalisova, NI; Zakutskii, AN1
Bhattacharya, SK1
Beaudeux, JL; Cottart, CH; Klimczak, C; Laguillier, C; Nivet-Antoine, V; Sebban, C1
Chernichovski, T; Grupper, A; Krishtol, N; Laron, I; Schwartz, D; Schwartz, IF1
Bertholon, C; Chapurlat, R; Gineyts, E; Munoz, F; Sornay-Rendu, E1
Bank, RA; Hooymans, JM; Los, LI; Ponsioen, TL; Snabel, JM; van Deemter, M; van der Worp, RJ1
Brummer, RJ; Heitmann, BL; Nieuwenhuizen, AG; van Vught, AJ; Veldhorst, MA; Westerterp-Plantenga, MS1
Aagaard, P; Couppé, C; Hansen, P; Kjaer, M; Kongsgaard, M; Kovanen, V; Magnusson, SP; Suetta, C1
Horowitz, JD; McNeil, JJ; Ngo, DT; Sverdlov, AL1
Liu, A; Ma, Y; Zhu, Z1
Jing, Y; Liu, P; Zhang, H1
Bode-Böger, SM; Fulge, B; Heimburg, A; Martens-Lobenhoffer, J; Scalera, F1
Chernichovski, T; Schwartz, D; Schwartz, IF1
Dörr, HG; Hauffa, BP; Wallaschofski, H1
Fahs, CA; Heffernan, KS; Patvardhan, EA; Ranadive, SM1
Alpert, DR; Cooke, JP; Crow, MK; Devereux, RB; Lockshin, MD; Perna, M; Roman, MJ; Salmon, JE; Sammaritano, L1
Hegg, CC; Jia, C1
Abe, T; Isobe, C; Terayama, Y1
Arnaud, E; Cartoni, R; Chrast, R; Courvoisier, DS; Martinou, JC; Médard, JJ; Poirot, O1
Hausmanowa-Petrusewicz, I; Kabzińska, D; Kochański, A; Sinkiewicz-Darol, E1
Devaraj, R; Ganesalingam, GS; Liu, P; Smith, PF; Zhang, H1
Andley, UP; Reilly, MA1
Asai, K; Hirata, K; Ichimaru, Y; Kanazawa, H; Kyoh, S; Tochino, Y1
Eguchi, N; Hirohama, J; Jinno, M; Miyazaki, A; Takeuchi, M; Teruya, K; Watanabe, A1
Beesley, MF; Choudhary, AK; Clay, S; Conway, BC; Ferenbach, DA; Hughes, J; Kluth, DC; Marson, LP; McKay, J; Nkejabega, NC; Vernon, MA1
Cremers, SG; Weinberg, PD; Wolffram, SJ1
Iemitsu, M; Kuno, S; Maeda, S; Murakami, H; Tanabe, K; Zempo, H1
Bogner, M; Elmadfa, I; Fabian, E1
Angelim, MK; de França, JP; de Lima e Silva, D; dos Santos, AA; Guedes, RC; Maia, LM; Monteiro, HM1
Li, LK; Li, XM; Song, B; Wu, XJ; Zhang, JH; Zhou, ZS1
Jurvelin, JS; Karjalainen, HM; Kokkonen, HT; Korhonen, RK; Kovanen, V; Kulmala, KA; Mäkelä, J; Rieppo, L; Tiitu, V; Töyräs, J1
Fan, X; Monnier, VM; Nemet, I; Potts, B; Strauch, CM; Xiaoqin, L1
Cauley, JA; Harris, T; Launer, L; Lindquist, K; Rosano, C; Satterfield, S; Schwartz, AV; Simonsick, EM; Vitartas, C; Vittinghoff, E; Yaffe, K1
Aussel, C; Cynober, L; Deutz, NE; Jourdan, M1
Begall, S; Dammann, P; Monnier, VM; Sell, DR; Strauch, C1
de Boer, TN; DeGroot, J; Huisman, AM; Lafeber, FP; Mastbergen, SC; Polak, AA; Vos, PA1
Taddei, S; Virdis, A1
Collie, ND; Jing, Y; Kennard, JT; Liu, P; Rushaidhi, M; Williams, JM; Zhang, H1
Goto, M; Iwaki-Egawa, S; Watanabe, Y1
Davidge, ST; Jiang, Y; Lekontseva, O; Schleppe, C1
Katsanos, CS; Mandarino, LJ; Meyer, C; Puga, GM1
Collie, ND; Gupta, N; Jing, Y; Liu, P; Zhang, H1
Aussel, C; Bahri, S; Chaumeil, JC; Crenn, P; Curis, E; Cynober, L; Moinard, C; Sfar, S; Zerrouk, N1
Aita, S; Iwanaga, T; Kameya, T; Kawai, Y; Matsushita, M; Ogawa, T; Okamoto, N; Saito, M; Yoneshiro, T1
Bryant-Angeloni, K; Dilger, RN; Lemme, A; Parsons, CM; Payne, RL1
Attia, JR; Carru, C; Mangoni, AA; McEvoy, M; Zinellu, A1
Chang, KJ; Choi, MJ1
Ağar, A; Bîlmen, S; Gümüşlü, S; Hacioğlu, G; Ozdemir, S; Yargiçoğlu, P1
Horiuchi, S; Jono, T; Kimura, T; Kitamura, T; Miyazaki, K; Nagai, R; Takamatsu, J; Yuzuriha, T1
Biemel, KM; Conrad, J; Lederer, MO1
Li, NS; Li, YJ; Lu, R; Peng, J; Zhu, HQ1
Aimaretti, G; Baffoni, C; Bellone, S; Benso, A; Broglio, F; Corneli, G; Origlia, C; Rovere, S; Tassone, F1
Allona, A; Angulo, J; Cuevas, P; Fernández, A; Gabancho, S; Martín-Morales, A; Moncada, I; Sáenz de Tejada, I1
Bode-Böger, SM; Fliser, D; Frölich, JC; Haller, H; Kielstein, JT; Ritz, E1
Al-Ruzzeh, S; Amrani, M; Chester, AH; Dewar, A; Nakamura, K; Rothery, S; Severs, NJ; Yacoub, MH1
Corzo, A; Hoehler, D; Moran, ET1
Anderstam, B; Bárány, P; Fehrman-Ekholm, I; Heimbürger, O; Lindholm, B; Pecoits-Filho, R; Qureshi, AR; Rodríguez Ayala, E; Stenvinkel, P; Suliman, ME1
Cutler, RG; Handy, A; Ingram, DK; Lane, MA; Mattison, JA; Monnier, VM; Obrenovich, ME; Roth, GS; Sell, DR1
Bode-Böger, SM; Fliser, D; Haller, H; Kielstein, JT1
Appleton, I; Bilkey, DK; Darlington, CL; Liu, P; Smith, PF1
Delemarre-van de Waal, HA; Heine, RJ; van Weissenbruch, MM; Veening, MA1
Frey, J; Meli, M; Perier, C1
Selley, ML1
WALIGORA, Z; WENDER, M1
MARTINEZ, C1
Chalisova, NI; Penniiaĭnen, VA1
Berkowitz, DE; Burke, S; Cernetich, A; Champion, HC; Hare, JM; Kim, S; Li, D; Minhas, KM; Nyhan, D; Shoukas, AA; White, R1
Bode-Böger, SM; Böger, RH; Brabant, G; Frölich, JC; Muke, J; Surdacki, A1
Kawata, K; Koga, Y; Mizuguchi, N; Okuda, T; Takasugi, Y; Watanabe, S; Yamanaka, S1
Boekelheide, K; Gray, DA; Rasoulpour, RJ; Schoenfeld, HA1
Bencko, V; Bezdícková, D; Pilin, A; Pudil, F; Sajdok, J; Zídková, J1
Aïtoubah, J; Itaya, S; Molotchnikoff, S1
Agrawal, CM; Li, X; Shen, X; Wang, X1
Ohhashi, T; Yashiro, Y1
Hirao, Y; Kitauchi, T; Ozono, S; Saka, T; Yoneda, T; Yoshida, K; Yoshikawa, M1
Ahlers, BA; Chin-Dusting, JP; Kaye, DM; Parnell, MM1
Larson, DF; Watson, RR; Yang, B1
Boer, P; Braam, B; Goldschmeding, R; Joles, JA; Koomans, HA; Racasan, S; van der Giezen, DM1
Azuma, H; Kihara, K; Kurosaki, E; Masuda, H; Sakai, Y; Yamauchi, Y1
Chiariello, M; Coppola, C; Curcio, A; Ellison, GM; Indolfi, C; Leosco, D; Li Volti, G; Rengo, F; Russo, VG; Torella, D; Torella, M1
Barnett, P; Bonert, VS; Elashoff, JD; Melmed, S1
Nishimura, H; Ruiz-Feria, CA; Yang, Y1
Alfarano, C; Banchelli, G; Cecchi, E; Cerbai, E; Cioni, L; Lodovici, M; Mugelli, A; Pirisino, R; Raimondi, L; Sartiani, L; Visioli, F1
Monnier, VM; Sell, DR4
Adman, ET; Kamath-Loeb, AS; Loeb, LA; Waite, M; Welcsh, P1
Ağar, A; Izgüt-Uysal, VN; Ozdemir, S; Ozkaya, YG; Yargiçoğlu, P1
Bowers, CY; Brill, KT; Mueller, EE; Patrie, JT; Veldhuis, JD; Weltman, A; Weltman, JY1
Bergamini, E; Bonanomi, G; Cavallini, G; Di Stefano, R; Mosca, F; Odetti, P; Parentini, I; Poggi, A; Rossi, S1
Menzel, EJ; Reihsner, R2
Barton, M; Lattmann, T; Münter, K; Shaw, S; Vetter, W1
Bourguignon, JP; Gérard, A; Lebrethon, MC; Matagne, V1
Birthelmer, A; Cassel, JC; Förstermann, U; Gödtel-Armbrust, U; Jackisch, R; Knörle, R; Lazaris, A; Schweizer, T1
Barton, M1
Hirose, H; Miyashita, K; Ogawa, T; Saito, I; Saruta, T1
Cavanal, Mde F; Coimbra, TM; Gil, FZ; Gomes, GN; Lucas, SR1
Habbel, S; Okonek, A; Quack, I; Rump, LC; Stegbauer, J; Vonend, O1
Calderón-Cortés, E; Clemente-Guerrero, M; Cortés-Rojo, C; Gaona-Zamudio, FJ; Saavedra-Molina, A; Sierra-Campos, E; Villalobos-Molina, R1
Chung, HY; Kim, YJ; Yokozawa, T1
Amano, S; Horiuchi, S; Kaji, Y; Koito, W; Okamoto, F; Oshika, T1
Deng, K; Nolan, JV; Wong, CW1
Barbi, C; Bonafé, M; Franceschi, C; Gravina, S; Mondello, C; Monti, D; Rossi, M; Salvioli, S; Storci, G; Tiberi, L; Tocco, F; Trapassi, C1
Black, SM; Farrow, KN; Jenkins, C; Konduri, GG; Lakshminrusimha, S; Mata-Greenwood, E; Russell, JA; Steinhorn, RH1
Ekambaram, P; Paul, V; Reddy, L1
Böger, RH; Freese, R; Maas, R; Schulze, F; Schwedhelm, E; Silberhorn, E1
Bowers, CY; Keenan, DM; Mielke, K; Miles, JM; Veldhuis, JD1
Adegoke, OA; Chevalier, S; Gougeon, R; Lamarche, M; Marliss, EB; Morais, JA; Wu, G1
Berkowitz, DE; Champion, HC; Hare, JM; Li, D; Nyhan, D; Ryoo, S; Shoukas, AA; Steppan, J; Wang, D; White, AR1
Holowatz, LA; Kenney, WL; Thompson, CS1
Aujard, F; Bentivoglio, M; Cayetanot, F; Perret, M1
Bode-Böger, SM; Bukowska, A; Lendeckel, U; Martens-Lobenhoffer, J; Scalera, F; Täger, M1
Suzuki, J1
Degroot, J; Maroudas, A; Roughley, P; Sakkee, N; Sivan, SS; Tsitron, E; van der Ham, F; Wachtel, E1
Bucek, RA; Haider, DG; Hron, G; Kyrle, PA; Minar, E; Mittermayer, F; Reiter, M; Wolzt, M1
Cipriano, C; Costarelli, L; Giacconi, R; Malavolta, M; Mocchegiani, E; Muti, E; Santarelli, L1
Boucher, ML; Gates, PE; Monahan, KD; Seals, DR; Silver, AE1
Babinet, C; Cohen-Tannoudji, M; Domenga, V; Gridley, T; Joutel, A; Langa, F; Lemaire, B; Monet, M; Souilhol, C; Tournier-Lasserve, E1
Bowers, CY; Cosma, M; Erickson, D; Farhy, LS; Mielke, K; Paulo, R; Veldhuis, JD1
Dreshaj, IA; Haxhiu, MA; Kamath, S; Martin, RJ; Sopi, RB; Zaidi, SI1
Carrithers, JA; Haus, JM; Trappe, SW; Trappe, TA1
Lang, J; Liu, AJ; Ma, YH; Zhang, GR1
Behnke, BJ; Delp, MD; Muller-Delp, JM; Spier, SA; Wu, G1
Bencko, V; Bezdícková, D; Pillin, A; Pudil, F1
De Lutiis, MA; Felaco, M; Franceschelli, S; Grilli, A; Mastrangelo, F; Patruno, A; Pesce, M; Speranza, L; Tetè, S; Vinciguerra, I1
Barlag, RE; Funovic, P; Jacob, RF; Korda, M; Kubant, R; Malinski, T; Mason, RP1
Bui, QU; Børsheim, E; Ferrando, AA; Kobayashi, H; Tissier, S; Wolfe, RR1
Heffernan, KS; Valentine, RJ; Vieira, VJ1
Huang, CC; Lin, WT; Tsai, SC1
Zhinkin, LN1
Frankel, BJ; Gerritsen, GC; Grodsky, GM; Heldt, AM1
Hill, RS; Rhoten, WB1
Bolgiano, DC; Halter, JB; McKnight, B; Porte, D; Ward, WK1
Chyun, JH; Griminger, P1
Nissim, I; Pereira, G; Segal, S; Yudkoff, M1
Arakawa, T; Chikaoka, H; Katsushima, N; Kobayashi, M; Minagawa, A; Saito, TG; Shioji, R1
Casale, G; De Nicola, P; Ferrero, E1
Bailey, CJ; Flatt, PR1
Braun, LD; Cornford, EM; Oldendorf, WH1
Costello, MJ; Morris, JG; Rogers, QR1
Kaji, H; Lamon, KD1
Bazer, FW; Tou, W; Wu, G1
Moliken, W; Russo, P; Wagerle, LC1
Bowyer, JF1
Fu, J; Fujioka, Y; Fujisawa, T; Fukuda, M; Ikegami, H; Kawaguchi, Y; Shen, G; Takekawa, K; Ueda, H; Yamato, E1
Nakashima, M; Vanhoutte, PM1
Cini, M; Dostert, P; Marrari, P; Strolin Benedetti, M1
Armstead, WM; Leffler, CW; Parfenova, H; Shibata, M; Zuckerman, SL1
Griffith, TM; Hutcheson, IR; Smith, JA1
Freedman, A; Garbán, H; González-Cadavid, N; Rajfer, J; Vernet, D1
Wu, G2
Baird, JD; Lindsay, RM; McIntyre, MA; Rossiter, SP; Smith, W; Williams, BC1
Bergamini, E; Bombara, M; Masiello, P; Novelli, M1
Aliev, G; Caparrotta, L; Chinellato, A; Fassina, G; Froldi, G; Pandolfo, L; Prosdocimi, M; Ragazzi, E1
Lang, MG; Lüscher, TF; Noll, G1
Knabe, DA; Wu, G1
Baynes, JW; Bell-Farrow, AD; Cefalu, WT; Fu, MX; Sonntag, WE; Thorpe, SR; Wang, ZQ1
Amerini, S; Ledda, F; Mantelli, L1
Nakamura, T; Pichel, JG; Westphal, H; Williams-Simons, L1
Nankervis, CA; Nowicki, PT1
Bellmunt, MJ; Cosso, L; Odetti, P; Pamplona, R; Portero, M; Prat, J1
Balligand, JL; Kelly, RA; Marsden, PA; Michel, T; Smith, TW1
Bliss, TV; Errington, ML; Li, YG; Murphy, KP; Nayak, A; Williams, JH1
de Novellis, V; Filippelli, A; Loffreda, A; Rossi, F1
Mancusi, G; Raberger, G; Schütz, W; Sexl, V1
Goto, Y; Hughes, SJ; Suzuki, K1
Fineman, JR; Soifer, SJ; Vanderford, PA; Wong, J1
McDonald, R; McGee, C; Reiser, K; Rucker, R1
Camanni, F; Ceda, GP; Ghigo, E; Goffi, S; Mucci, M; Muller, EE; Valcavi, R; Valenti, G; Zini, M1
Boja, B; Monnier, V; Moskowitz, RW; Pokharna, HK1
Flynn, NE; Knabe, DA; Wu, G; Yan, W1
Arvat, E; Bellone, J; Camanni, F; Ghigo, E; Gianotti, L; Goffi, S; Maccario, M; Procopio, M1
Pautler, EL1
Arvat, E; Camanni, F; Deghenghi, R; Ghigo, E; Gianotti, L; Grottoli, S; Imbimbo, BP; Lenaerts, V1
Bacon, EE; Blanchard, EJ; Kellum, JA; Kruckeberg, WC; Reckelhoff, JF; Wesley, AJ1
Alexander, LR; Bauman, WA; Flanagan, S; Spungen, AM; Tsitouras, PD; Zhong, YG1
Camanni, F; Ceda, GP; Cocchi, D; Ghigo, E; Goffi, S; Mucci, M; Müller, EE; Valcavi, R; Valenti, G; Zini, M1
Futami, Y; Maki, T; Sonaka, I1
Lizza, EF; Zorgniotti, AW1
Abe, I; Fujii, K; Fujishima, M; Kobayashi, K; Takata, Y; Tominaga, M1
Anderson, S; Houghton, DC; Tank, JE; Vora, JP1
Anderson, WR; Chao, CC; Hu, S; Peterson, PK1
Arvat, E; Bellone, J; Boffano, GM; Boghen, MF; Camanni, F; Ghigo, E; Mucci, M; Nicolosi, M; Rizzi, G1
Arribas, S; Balfagón, G; Marín, J; Ponte, A; Salaices, M1
Andreucci, VE; Conte, G; De Nicola, L; Giliberti, A; Margri, P; Sabbatini, M; Sansone, G; Sepe, V; Uccello, F1
Garaschuk, O; Kovalchuk, Yu; Krishtal, O1
Reiser, KM1
Höger, H; Lubec, B; Lubec, G; Radner, W; Salzer, H1
Hoshino, H; Inoue, T; Kawana, K; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A1
Farrar, MA; Magness, RR; Shaul, PW1
Manning, RD; Reckelhoff, JF1
Carlson, EC; Monnier, VM; Sell, DR1
Monnier, V1
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Federlin, K; Linn, T; Loewk, E; Schneider, K1
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Hiramatsu, S; Inoue, K; Nawata, H; Sako, Y; Umeda, F1
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Caffarri, G; Capretti, L; Chiodera, P; Coiro, V; Davoli, C; Volpi, R1
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Pokharna, HK; Pottenger, LA1
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Phillips, FM; Pokharna, HK1
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Caramelo, C; Casado, S; Cernadas, MR; de Frutos, T; Fernández, P; García-Durán, M; González-Fernández, F; Guerra, J; Millás, I; Montón, M; Rico, L; Rodrigo, J; Rodríguez-Feo, JA; Sánchez de Miguel, L1
Horiuchi, S; Kimura, T; Miyakawa, T; Miyata, T; Takamatsu, J1
Andersson, A; Carlsson, PO; Jansson, L1
Tiritilli, A1
Aimaretti, G; Arvat, E; Bartolotta, E; Bellone, J; Bellone, S; Deghenghi, R; Ghigo, E; Sgattoni, C1
Kanai, M; Nagata, M; Nagayama, Y; Nakamura, K; Saito, N; Takahashi, S; Yoshihara, K1
Akyol, M; Bell, J; Briggs, JD; Dominiczak, MH; Shaw, S1
Baynes, JW; Degenhardt, TP; Thorpe, SR1
Avery, N; Crean, JK; Duance, VC; Eisenstein, SM; Menage, J; Roberts, S; Sims, TJ; Smith, S1
Hata, F; Ishii, T; Niioka, S; Nishio, H; Okishio, Y; Takatsuji, K; Takeuchi, T; Yamaji, M1
Francischetti, A; Frohlich, ED; Susic, D1
Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J1
Aotaki-Keen, A; Handa, JT; Hjelmeland, LM; Lutty, GA; Matsunaga, H; Miyata, T; te Koppele, JM; Verzijl, N1
Alhumadi, NH; Iqbal, M; Klandorf, H; Probert, LL1
Bank, RA; Bijlsma, JW; DeGroot, J; Lafeber, FP; TeKoppele, JM; Verzijl, N1
Baldwin, AC; Levisetti, M; Pick, AJ; Polonsky, KS; Pugh, W; Sreenan, S1
Bank, RA; Hazleman, BL; Oostingh, G; Riley, GP; TeKoppele, JM1
Aotaki-Keen, A; Farboud, B; Handa, JT; Hjelmeland, LM; Miyata, T1
Blum-Degen, D; Gerlach, M; Heinemann, T; Lan, J; Leblhuber, F; Paulus, W; Pedersen, V; Riederer, P1
Fairand, A; Goutal, I; Husson, A1
Keshava, C; McCanlies, EC; Sharp, DS; Sun, Y; Weston, A1
Baynes, JW; Litchfield, JE; Thorpe, SR1
Castagnola, M; Corda, M; De Rosa, MC; Fais, A; Ficarra, S; Giardina, B; Manca, L; Masala, B; Olianas, A; Pellegrini, MG; Sanna, MT; Zappacosta, B1
Nagano, A; Oikawa, M; Takahashi, M1
Lingelbach, LB; McDonald, RB; Mitchell, AE; Rucker, RB1
Langkamp-Henken, B; Lewis, B1
Bank, RA; Bayliss, MT; Baynes, JW; Bijlsma, JW; DeGroot, J; Lafeber, FP; Oldehinkel, E; Tekoppele, JM; Thorpe, SR; Verzijl, N1
Cheng, J; Juang, S; Lee, J; Liu, T; Yu, W1
Al-Humadi, NH; Iqbal, M; Kenney, PB; Klandorf, H1
Meininger, CJ; Wu, G1
Aimaretti, G; Arvat, E; Baffoni, C; Bellone, S; Benso, L; Camanni, F; Corneli, G; Di Vito, L; Ghigo, E1
Gaillard, RC; Giacomini, M; Grouzmann, E; Pralong, FP; Voirol, M1
Arvat, E; Broglio, F; Ceda, GP; Deghenghi, R; Di Vito, L; Ghigo, E; Gianotti, L; Ramunni, J1
Aimaretti, G; Cerbone, G; Colao, A; Di Somma, C; Faggiano, A; Klain, M; Lombardi, G; Pivonello, R; Salvatore, M1
Fedele, D; Lapolla, A; Traldi, P1
Gerstenblith, G; Hare, JM; Lakatta, EG; Ricker, KM; Rosas, GO; Vandegaer, K; Zieman, SJ1
Brown, G; Castro, E; Deeb, SS; Edland, SD; Erkkola, R; Lee, L; Louhija, J; Martin, GM; Ogburn, CE; Oshima, J; Panduro, A; Penttinen, R; Riestra, R; Tilvis, R; Wang, L1
Austic, RE; Park, BC1
Battistini, B; Floras, JS; Meneilly, GS1
Asakawa, A; Cheng, JT; Dobashi, R; Fujimiya, M; Inui, A; Kaga, T; Kasuga, M; Liu, IM; Morimoto, Y; Nishimura, N; Okita, M; Ueno, N1
Aikawa, K; Okamura , H; Yamaguchi, O; Yokota, T1
Iqbal, M; Klandorf, H; Rathore, DS; Shi, X; Van Dyke, K1
Fujimoto, D; Hiki, Y; Iijima, K; Irie, S; Kusunoki, H; Maeda, K; Miyata, S; Nakata, M; Odani, H; Yasuda, Y1
Chen, BM; Deng, HW; Li, YJ; Xiong, Y; Yuan, LW1
Abe, T; Isobe, C; Murata, T; Sato, C; Tohgi, H1
Donabedian, M; Hare, JM; Rosas, GO; Vandegaer, K; Zieman, SJ1
Corvol, P; Kempf, H; Nishimura, H; Wideman, RF; Xi, Z; Zhang, L1
Bank, RA; Bayliss, MT; Bijlsma, JW; DeGroot, J; Lafeber, FP; Maroudas, A; TeKoppele, JM; Verzijl, N1
Bank, RA; Bijlsma, JW; DeGroot, J; Lafeber, FP; TeKoppele, JM; Verzijl, N; Wenting-Van Wijk, MJ1
Al Banchaabouchi, M; D'hooge, R; De Deyn, PP; Marescau, B; Van Marck, E1
Frohlich, ED; Susic, D; Varagic, J1
Bank, RA; Baynes, JW; Ben, ZC; Bijlsma, JW; Brau-Benjamin, O; DeGroot, J; Lafeber, FP; Maroudas, A; Mizrahi, J; Schalkwijk, CG; TeKoppele, JM; Thorpe, SR; Verzijl, N1
Arai, K; Chikuda, M; Matsumoto, Y; Takahashi, M1
Arafah, BM; Biller, BM; Bonert, V; Chipman, JJ; Cook, DM; Hartman, ML; Kleinberg, DL; Samuels, MH; Stavrou, S; Zagar, A1
Chalkley, SM; Chisholm, DJ; Hettiarachchi, M; Kraegen, EW1
Baylis, C; Greenfeld, Z; Mistry, SK; Morris, SM1
Csiszar, A; Edwards, JG; Kaley, G; Kaminski, P; Koller, A; Ungvari, Z; Wolin, MS1
Antonicelli, R; Barbieri, M; Berardelli, M; Bonafè, M; Cardelli, M; Cavallone, L; De Benedictis, G; Franceschi, C; Giovagnetti, S; Gueresi, P; Lisa, R; Marchegiani, F; Marra, M; Olivieri, F; Paolisso, G; Passeri, G; Pieri, C; Tesei, S; Troiano, L1
Hu, CP; Li, YJ; Liao, EY; Lu, R; Wu, XP1
Eberl, R; Partsch, G; Schwarzer, C; Tausch, G1
Daniels, VG; Murphy, S1
Baker, GT3
Bergström, J; Eriksson, S; Fürst, P; Hellström, K; Möller, P1
Hassan, AS; Milner, JA1
Gopalakrishna, R; Nagarajan, B1
Deyl, Z; Helm, R; Vancikova, O1
Casale, G; Ciaponi, A; Ferrero, E; Tassi, G1
Milner, JA; Visek, WJ1
Takemura, Y; Yoshie, Y1
Gahagan, JH; Martin, RJ; Wangsness, PJ1
Day, RW; Ignarro, LJ; Klitzner, TS; Lai, WW1
Hisayama, T; Moritoki, H; Takeuchi, S; Yoshikawa, T1
Hisayama, T; Kondoh, W; Miyano, H; Moritoki, H; Takeuchi, S1
Barnes, PJ; Haworth, SG; Hislop, AA; Liu, SF1
Arvat, E; Boffano, GM; Boghen, MF; Ghigo, E; Goffi, S; Imperiale, E; Magliona, A; Mazza, E; Santi, I; Valetto, MR1
Hiramatsu, Y; Itokazu, Y; Kinoshita, T; Koida, M; Kurio, W; Maeda, H; Manno, K; Nakamuta, H; Ogawa, Y; Ozaki, K1
Grandhee, S; Ibrahim, SA; Miyata, S; Monnier, VM; Nagaraj, RH; Odetti, P; Sell, DR1
Aratan-Spire, S; Bulant, M; Ebiou, JC; Nicolas, P1
Bernasconi, S; Cozzini, A; Ghigo, E; Ghizzoni, L; Panza, C; Volta, C; Ziveri, M1
Abrass, IB; Beard, JC; Cain, KC; Cerqueira, MD; Fellingham, GW; Kahn, SE; Larson, VG; Schwartz, RS; Stratton, JR1
Hasegawa, T; Morita, K; Nakajima, S; Nishimaki, K; Takagi, S1
Fujie, M; Horiuchi, K; Inoue, T; Kushida, K; Ohishi, T; Takahashi, M; Uchiyama, A1
Bergamini, E; Bombara, M; Fierabracci, V; Masiello, P; Novelli, M1
Gross, KL; Hartman, WJ; Prior, RL; Ronnenberg, A1
Fogarty, J; Grandhee, SK; Lapolla, A; Monnier, VM; Nagaraj, RH; Odetti, P; Sell, DR1
Hasegawa, G; Kondo, M; Nakamura, N; Nakano, K; Sawada, M1
Gross, KL; Hartman, WJ; Meydani, SN; Prior, RL; Ronnenberg, AG1
Fujita, N; Nagao, T; Yamazaki, J1
Wakabayashi, Y; Yamada, E1
Monnier, VM; Nagaraj, RH; Ortwerth, BJ; Prabhakaram, M; Sell, DR1
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Fürnsinn, C; Komjati, M; Madsen, OD; Schneider, B; Waldhäusl, W1
Aizawa, T; Komatsu, M; Komiya, I; Nagasawa, Y; Takasu, N; Yamada, T; Yokokawa, N1
Bailbé, D; Giroix, MH; Goto, Y; Portha, B; Serradas, P; Suzuki, K1
Abman, SH; Chatfield, BA; Hall, SL; McMurtry, IF; Rodman, DM1
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Swanson, DR1
Ayala, A; Bautista, J; Gordillo, E; Machado, A1
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Kobori, H1
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Inoue, K; Shimizu, T1
Wilson, RP1
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Ayala, A; Bautista, J; F-Lobato, M; Gordillo, E; Machado, A1
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Busby, WF; Hele, P1
Kanungo, MS; Shukla, SP1
Pyhtilä, MJ; Sherman, FG1

Reviews

36 review(s) available for arginine and Aging

ArticleYear
Functional Amino Acids and Autophagy: Diverse Signal Transduction and Application.
    International journal of molecular sciences, 2021, Oct-22, Volume: 22, Issue:21

    Topics: Aging; Amino Acids; Arginine; Autophagy; Glutamine; Humans; Leucine; Mechanistic Target of Rapamycin Complex 1; Methionine; Neoplasms; Neurodegenerative Diseases; Obesity; Signal Transduction

2021
L-Citrulline Supports Vascular and Muscular Benefits of Exercise Training in Older Adults.
    Exercise and sport sciences reviews, 2020, Volume: 48, Issue:3

    Topics: Aging; Arginine; Biological Availability; Body Mass Index; Citrulline; Dietary Supplements; Endothelium, Vascular; Exercise; Humans; Muscle Proteins; Muscle Strength; Muscle, Skeletal; Nitric Oxide; Oxygen Consumption; Physical Conditioning, Human

2020
Green Tea Suppresses Brain Aging.
    Molecules (Basel, Switzerland), 2021, Aug-12, Volume: 26, Issue:16

    Topics: Aging; Animals; Arginine; Brain; Catechin; Glutamates; Humans; Tea

2021
Agmatine: multifunctional arginine metabolite and magic bullet in clinical neuroscience?
    The Biochemical journal, 2017, 07-26, Volume: 474, Issue:15

    Topics: Aging; Agmatine; Animals; Arginine; Central Nervous System Diseases; Humans; Mental Disorders; Metabolic Networks and Pathways; Neuralgia

2017
New horizons in arginine metabolism, ageing and chronic disease states.
    Age and ageing, 2019, 11-01, Volume: 48, Issue:6

    Topics: Aged; Aging; Arginine; Chronic Disease; Homoarginine; Humans

2019
Asymmetric (ADMA) and Symmetric (SDMA) Dimethylarginines in Chronic Kidney Disease: A Clinical Approach.
    International journal of molecular sciences, 2019, Jul-26, Volume: 20, Issue:15

    Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; Metabolic Networks and Pathways; Molecular Targeted Therapy; Prognosis; Renal Dialysis; Renal Insufficiency, Chronic

2019
Asymmetric Dimethylarginine (ADMA): a promising biomarker for cardiovascular disease?
    Current topics in medicinal chemistry, 2013, Volume: 13, Issue:2

    Topics: Aging; Amidohydrolases; Arginine; Biomarkers; Cardiovascular Diseases; Cerebrovascular Disorders; Chromatography, High Pressure Liquid; Diabetes Complications; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Mass Spectrometry; Nitric Oxide; Oxidative Stress; Reference Values; Risk Factors; Smoking

2013
Is there a possible single mediator in modulating neuroendocrine-thymus interaction in ageing?
    Current aging science, 2013, Volume: 6, Issue:1

    Topics: Aging; Animals; Arginine; Cytokines; Humans; Hypothalamo-Hypophyseal System; Melatonin; Mice; Neuroimmunomodulation; Neurosecretory Systems; Signal Transduction; Thymus Gland; Zinc

2013
[Determinants of bone quality and strength independent of bone remodeling].
    Clinical calcium, 2016, Volume: 26, Issue:1

    Topics: Aging; Animals; Arginine; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Collagen; Diphosphonates; Female; Fractures, Stress; Glucocorticoids; Glycation End Products, Advanced; Humans; Lysine; Male; Osteoporosis; Precision Medicine; Selective Estrogen Receptor Modulators

2016
Oxidative Stress and Cardiovascular Aging: Interaction Between NRF-2 and ADMA.
    Current cardiology reviews, 2017, Volume: 13, Issue:3

    Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Endothelium, Vascular; Humans; NF-E2-Related Factor 2; Oxidative Stress; Signal Transduction

2017
Regenerating muscle with arginine methylation.
    Transcription, 2017, 05-27, Volume: 8, Issue:3

    Topics: Aging; Animals; Arginine; Humans; Methylation; Muscle Proteins; Muscles; Muscular Diseases; Myoblasts; Protein-Arginine N-Methyltransferases; Regeneration

2017
Arginase and vascular aging.
    Journal of applied physiology (Bethesda, Md. : 1985), 2008, Volume: 105, Issue:5

    Topics: Aging; Animals; Arginase; Arginine; Cardiovascular Agents; Drug Design; Elasticity; Endothelium, Vascular; Enzyme Inhibitors; Humans; Models, Molecular; Nitric Oxide; Nitric Oxide Synthase; Protein Conformation; Signal Transduction; Structure-Activity Relationship

2008
Retinal deimination in aging and disease.
    IUBMB life, 2009, Volume: 61, Issue:5

    Topics: Aging; Arginine; Humans; Hydrolases; Neurodegenerative Diseases; Protein Processing, Post-Translational; Protein-Arginine Deiminase Type 2; Protein-Arginine Deiminases; Retinal Diseases

2009
[Biology of arterial ageing and arteriosclerosis].
    Comptes rendus biologies, 2009, Volume: 332, Issue:5

    Topics: Adult; Aged; Aging; Arginine; Arteriosclerosis; Atherosclerosis; Calcinosis; Diagnostic Techniques, Cardiovascular; Endothelium, Vascular; Extracellular Matrix; Female; Humans; Hypertension; Lipoproteins; Male; Middle Aged; Monocytes; Osteoblasts; Tunica Media; Vascular Resistance

2009
L-arginine as a nutritional prophylaxis against vascular endothelial dysfunction with aging.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:1

    Topics: Aging; Anti-Inflammatory Agents; Arginine; Cardiovascular Diseases; Endothelial Cells; Humans; Nitric Oxide; Nutritional Physiological Phenomena; Randomized Controlled Trials as Topic; Treatment Outcome

2010
Endothelial aging and gender.
    Maturitas, 2012, Volume: 71, Issue:4

    Topics: Aging; Androgens; Arginine; Atherosclerosis; Endothelium, Vascular; Estrogens; Female; Humans; Nitric Oxide; Reactive Oxygen Species; Sex Factors

2012
Citrulline: from metabolism to therapeutic use.
    Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:3

    Topics: Aging; Animals; Arginine; Biological Transport; Cardiovascular Diseases; Citrulline; Humans; Intestinal Mucosa; Models, Animal; Muscle, Skeletal; Protein Biosynthesis; Sarcopenia

2013
Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine?
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:7

    Topics: Adult; Aged; Aging; Arginine; Enzyme Inhibitors; Humans; Kidney; Kidney Diseases

2003
Native protein glycoxidation and aging.
    The journal of nutrition, health & aging, 2003, Volume: 7, Issue:4

    Topics: Aging; Arginine; Carbohydrate Metabolism; Free Radicals; Glucose; Glycation End Products, Advanced; Glycosylation; Half-Life; Humans; Lysine; Maillard Reaction; Oxidation-Reduction; Proteins

2003
[Age-related post-translational modification of proteins in human tissue and its use determination of age in forensic medicine. Review].
    Soudni lekarstvi, 2003, Volume: 48, Issue:4

    Topics: Aging; Arginine; Forensic Medicine; Glycation End Products, Advanced; Humans; Lysine; Protein Processing, Post-Translational

2003
Ageing as a determinant of renal and vascular disease: role of endothelial factors.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2005, Volume: 20, Issue:3

    Topics: Aging; Arginine; Endothelial Cells; Endothelium, Vascular; Humans; Kidney Diseases; Nitric Oxide; Vascular Diseases

2005
Plasticity of neuroendocrine-thymus interactions during ontogeny and ageing: role of zinc and arginine.
    Ageing research reviews, 2006, Volume: 5, Issue:3

    Topics: Aging; Animals; Arginine; Dietary Supplements; Growth Hormone; Humans; Immune System; Melatonin; Neurosecretory Systems; Rejuvenation; Thymus Gland; Zinc

2006
Microvascular function and ageing L-arginine, tetrahydrobiopterin and the search for the fountain of vascular youth.
    The Journal of physiology, 2008, Apr-15, Volume: 586, Issue:8

    Topics: Aging; Animals; Arginine; Arterioles; Biopterins; Endothelium, Vascular; Muscle, Skeletal; Rats; Vasodilation

2008
[Neuroregulation of GH secretion in aging].
    Minerva endocrinologica, 1993, Volume: 18, Issue:3 Suppl 1

    Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Child, Preschool; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Infant; Insulin-Like Growth Factor I; Middle Aged; Neuropeptides; Neurotransmitter Agents; Recombinant Proteins; Reference Values; Somatostatin

1993
[Non-enzymatic glycosylation of proteins. Complications of diabetes mellitus, aging and kidney failure].
    Presse medicale (Paris, France : 1983), 1993, Oct-09, Volume: 22, Issue:30

    Topics: Aging; Arginine; Blood Glucose; Diabetes Mellitus; Diabetic Neuropathies; Glycation End Products, Advanced; Glycosylation; Guanidines; Humans; Lysine; Maillard Reaction; Renal Insufficiency

1993
Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:12

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Elastin; Glycation End Products, Advanced; Glycosylation; Humans; Imidazoles; Lysine; Maillard Reaction; Malondialdehyde; Norleucine; Pyrroles

1996
New biomarkers of Maillard reaction damage to proteins.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11 Suppl 5

    Topics: Aging; Arginine; Biomarkers; Diabetes Complications; Diabetes Mellitus; Glycation End Products, Advanced; Glycosylation; Humans; Lysine; Maillard Reaction; Molecular Structure; Norleucine; Oxidation-Reduction; Proteins; Pyrroles

1996
Posttranslational arginylation of brain proteins.
    Neurochemical research, 1997, Volume: 22, Issue:4

    Topics: Aging; Amyloid beta-Peptides; Animals; Arginine; Brain; Microtubule-Associated Proteins; Nerve Tissue Proteins; Protein Processing, Post-Translational; Ubiquitins

1997
[Nitric oxide (NO), vascular protection factor. NO: role in aging].
    Presse medicale (Paris, France : 1983), 1998, Jun-13, Volume: 27, Issue:21

    Topics: Aging; Animals; Arginine; Endothelium, Vascular; Humans; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Vasoconstriction

1998
Arginine nutrition and cardiovascular function.
    The Journal of nutrition, 2000, Volume: 130, Issue:11

    Topics: Aging; Animals; Arginine; Cardiovascular Diseases; Humans; Nitric Oxide; Nutritional Physiological Phenomena

2000
AGE in micro- and macroangiopathy.
    Contributions to nephrology, 2001, Issue:131

    Topics: Aging; Animals; Arginine; Arteriosclerosis; Cell Adhesion; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Humans; Interferon-gamma; Lysine; Membrane Proteins; Microcirculation; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class B; T-Lymphocytes; Vascular Diseases

2001
Maillard reaction-mediated molecular damage to extracellular matrix and other tissue proteins in diabetes, aging, and uremia.
    Diabetes, 1992, Volume: 41 Suppl 2

    Topics: Aging; Arginine; Diabetes Mellitus; Extracellular Matrix Proteins; Humans; Lysine; Maillard Reaction; Proteins; Uremia

1992
Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia.
    Diabetes/metabolism reviews, 1991, Volume: 7, Issue:4

    Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Cross-Linking Reagents; Diabetes Mellitus; Dura Mater; Humans; Lysine; Uremia

1991
Somatomedin C and arginine: implicit connections between mutually isolated literatures.
    Perspectives in biology and medicine, 1990,Winter, Volume: 33, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Aging; Animals; Arginine; Growth; Growth Hormone; Humans; Insulin-Like Growth Factor I; Nutrition Disorders; Somatomedins

1990
Protein and amino acid requirements of fishes.
    Annual review of nutrition, 1986, Volume: 6

    Topics: Aging; Amino Acids; Animals; Arginine; Dietary Proteins; Energy Intake; Fishes; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Species Specificity; Threonine; Tryptophan; Valine

1986
Enzymes of arginine and urea synthesis.
    Advances in enzymology and related areas of molecular biology, 1973, Volume: 39

    Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Arginase; Arginine; Binding Sites; Carbamates; Dietary Proteins; Humans; Kinetics; Liver; Lyases; Organ Specificity; Ornithine; Ornithine Carbamoyltransferase; Phosphotransferases; Species Specificity; Succinates; Urea

1973

Trials

29 trial(s) available for arginine and Aging

ArticleYear
Application of multivariate longitudinal models in SIRT6, FBS, and BMI analysis of the elderly.
    The aging male : the official journal of the International Society for the Study of the Aging Male, 2019, Volume: 22, Issue:4

    Topics: Aging; Anthropometry; Arginine; Body Composition; Body Mass Index; Dietary Supplements; Exercise Therapy; Humans; Longevity; Male; Middle Aged; Monitoring, Physiologic; Sirtuins; Treatment Outcome

2019
Aortic wave velocity: a noninvasive method to measure the stiffness of arteries and the clinical results of supplements that appear to improve arterial stiffness.
    Current aging science, 2013, Volume: 6, Issue:1

    Topics: Adult; Aged; Aging; Arginine; Cardiovascular Diseases; Carnosine; Dietary Supplements; Female; Glycation End Products, Advanced; Guanidines; Humans; Male; Middle Aged; Pulse Wave Analysis; Resveratrol; Risk Factors; Stilbenes; Vascular Stiffness

2013
Chronic heart failure and aging - effects of exercise training on endothelial function and mechanisms of endothelial regeneration: Results from the Leipzig Exercise Intervention in Chronic heart failure and Aging (LEICA) study.
    European journal of preventive cardiology, 2016, Volume: 23, Issue:4

    Topics: Aged; Aging; Arginine; Blood Flow Velocity; Cell Count; Chemokine CXCL12; Endothelial Progenitor Cells; Endothelium, Vascular; Exercise Therapy; Heart Failure; Humans; Intercellular Adhesion Molecule-1; Middle Aged; Prospective Studies; Radial Artery; Regeneration; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A

2016
Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens.
    Journal of animal physiology and animal nutrition, 2016, Volume: 100, Issue:2

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Diet; Female; Fertility; Glycine; Humans; Insemination, Artificial; Male; Sperm-Ovum Interactions; Vitelline Membrane

2016
Effects of 6-month supplementation with β-hydroxy-β-methylbutyrate, glutamine and arginine on vascular endothelial function of older adults.
    European journal of clinical nutrition, 2016, Volume: 70, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Brachial Artery; C-Reactive Protein; Cardiovascular Diseases; Dietary Supplements; Double-Blind Method; Endothelium, Vascular; Fasting; Female; Glutamine; Humans; Male; Tumor Necrosis Factor-alpha; Valerates; Vasodilation

2016
Effects of handgrip exercise or inorganic nitrate supplementation on 24-h ambulatory blood pressure and peripheral arterial function in overweight and obese middle age and older adults: A pilot RCT.
    Maturitas, 2015, Volume: 82, Issue:2

    Topics: Adult; Aged; Aging; Arginine; Beta vulgaris; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dietary Supplements; Exercise; Female; Hand Strength; Humans; Hypertension; Male; Middle Aged; Nitrates; Obesity; Overweight; Phytotherapy; Pulsatile Flow; Treatment Outcome

2015
Nutritional Interventions that Slow the Age-Associated Decline in Renal Function in a Canine Geriatric Model for Elderly Humans.
    The journal of nutrition, health & aging, 2016, Volume: 20, Issue:10

    Topics: Absorptiometry, Photon; Aged; Aging; Animals; Arginine; Biomarkers; Body Weight; Carnitine; Cross-Sectional Studies; Diet; Dietary Proteins; Dietary Supplements; Disease Models, Animal; Dogs; Female; Fish Oils; Fruit; Geriatric Assessment; Glomerular Filtration Rate; Humans; Kidney; Male; Thioctic Acid; Vegetables

2016
Increased plasma availability of L-arginine in the postprandial period decreases the postprandial lipemia in older adults.
    Nutrition (Burbank, Los Angeles County, Calif.), 2013, Volume: 29, Issue:1

    Topics: Administration, Oral; Aged; Aging; Arginine; Biological Availability; Cardiovascular Diseases; Dietary Fats; Fatty Acids, Nonesterified; Humans; Hyperlipidemias; Infusions, Intravenous; Male; Postprandial Period; Risk Factors; Triglycerides

2013
Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's disease.
    Neurobiology of aging, 2003, Volume: 24, Issue:7

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arginine; Enzyme Inhibitors; Female; Homocysteine; Humans; Male; Matched-Pair Analysis; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Reference Values; Statistics as Topic

2003
Oral L-arginine improves endothelial function in healthy individuals older than 70 years.
    Vascular medicine (London, England), 2003, Volume: 8, Issue:2

    Topics: Administration, Oral; Aged; Aging; Analysis of Variance; Arginine; Blood Flow Velocity; Brachial Artery; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Humans; Linear Models; Male; Prospective Studies; Vasodilation

2003
An age-related decline in endothelial function is not associated with alterations in L-arginine transport in humans.
    Journal of hypertension, 2004, Volume: 22, Issue:2

    Topics: Acetylcholine; Adult; Aged; Aging; Arginine; Biological Transport; Endothelium, Vascular; Forearm; Humans; Male; Middle Aged; Monocytes; Nitric Oxide Synthase; Plethysmography; Reference Values; Vasodilation; Vasodilator Agents

2004
Contributions of gender and systemic estradiol and testosterone concentrations to maximal secretagogue drive of burst-like growth hormone secretion in healthy middle-aged and older adults.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:12

    Topics: Aged; Aging; Arginine; Estradiol; Exercise; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Male; Middle Aged; Sex Characteristics; Somatostatin; Stimulation, Chemical; Testosterone

2004
Long-term effects of early life L-arginine supplementation on growth performance, lymphoid organs and immune responses in Leghorn-type chickens.
    British poultry science, 2005, Volume: 46, Issue:3

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Antibodies; Arginine; Chickens; Dietary Supplements; Immunoglobulin M; Lymphoid Tissue; Male; Serum Albumin, Bovine; Weight Gain

2005
Testosterone supplementation in healthy older men drives GH and IGF-I secretion without potentiating peptidyl secretagogue efficacy.
    European journal of endocrinology, 2005, Volume: 153, Issue:4

    Topics: Adipose Tissue; Aged; Aging; Arginine; Cross-Over Studies; Double-Blind Method; Drug Combinations; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Luminescence; Male; Middle Aged; Oligopeptides; Radiography, Abdominal; Robotics; Testosterone; Tomography, X-Ray Computed; Viscera

2005
Tripartite control of growth hormone secretion in women during controlled estradiol repletion.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:6

    Topics: Adult; Aged; Aging; Arginine; Estradiol; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Middle Aged; Oligopeptides; Postmenopause; Premenopause

2007
Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects.
    The Journal of clinical endocrinology and metabolism, 1994, Volume: 79, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Drug Combinations; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Infusions, Intravenous; Male; Oligopeptides

1994
Low doses of either intravenously or orally administered arginine are able to enhance growth hormone response to growth hormone releasing hormone in elderly subjects.
    Journal of endocrinological investigation, 1994, Volume: 17, Issue:2

    Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Arginine; Dose-Response Relationship, Drug; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Injections, Intravenous; Male

1994
Arginine enhances the growth hormone-releasing activity of a synthetic hexapeptide (GHRP-6) in elderly but not in young subjects after oral administration.
    Journal of endocrinological investigation, 1994, Volume: 17, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aging; Amino Acid Sequence; Arginine; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Injections, Intravenous; Insulin-Like Growth Factor I; Male; Molecular Sequence Data; Oligopeptides

1994
Oral arginine-lysine does not increase growth hormone or insulin-like growth factor-I in old men.
    Journal of gerontology, 1993, Volume: 48, Issue:4

    Topics: Administration, Oral; Adult; Aged; Aging; Arginine; Drug Combinations; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin-Like Growth Factor I; Lysine; Male; Middle Aged

1993
Age-dependent decrease in the growth hormone response to growth hormone-releasing hormone in normally cycling women.
    Fertility and sterility, 1996, Volume: 66, Issue:2

    Topics: Adolescent; Adult; Aging; Arginine; Cholinesterase Inhibitors; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Menstrual Cycle; Middle Aged; Pyridostigmine Bromide; Somatostatin

1996
Aging abolishes the renal response to L-arginine infusion in essential hypertension.
    Kidney international. Supplement, 1996, Volume: 55

    Topics: Adult; Aged; Aging; Arginine; Blood Pressure; Enzyme Inhibitors; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; Kidney Function Tests; Male; Nitric Oxide; Nitric Oxide Synthase

1996
Effect of arginine and ornithine infusions on luteinizing hormone secretion in prepubertal ewes.
    Journal of animal science, 1996, Volume: 74, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Arginine; Female; Infusions, Intravenous; Luteinizing Hormone; Ornithine; Radioimmunoassay; Sheep

1996
Reproducibility of the growth hormone response to stimulation with growth hormone-releasing hormone plus arginine during lifespan.
    European journal of endocrinology, 1996, Volume: 135, Issue:5

    Topics: Adult; Aged; Aging; Arginine; Child; Drug Therapy, Combination; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypopituitarism; Male; Reference Values; Reproducibility of Results; Time Factors

1996
Hypertension causes premature aging of endothelial function in humans.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:3

    Topics: Acetylcholine; Adult; Aged; Aging; Arginine; Blood Circulation; Drug Interactions; Endothelium; Female; Humans; Hypertension; Male; Middle Aged; Nitroprusside; Vasodilation; Vasodilator Agents

1997
Relationship between mechanical properties and pentosidine in tendon: effects of age, diet restriction, and aminoguanidine in broiler breeder hens.
    Poultry science, 2000, Volume: 79, Issue:9

    Topics: Aging; Animals; Arginine; Biomechanical Phenomena; Chickens; Diet; Elasticity; Female; Food Deprivation; Guanidines; Lysine; Regression Analysis; Tendons; Tensile Strength

2000
Retesting young adults with childhood-onset growth hormone (GH) deficiency with GH-releasing-hormone-plus-arginine test.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:10

    Topics: Adolescent; Adult; Aging; Arginine; Child; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypopituitarism; Insulin-Like Growth Factor I; Male; Radioimmunoassay

2000
Identification of N(omega)-carboxymethylarginine, a new advanced glycation endproduct in serum proteins of diabetic patients: possibility of a new marker of aging and diabetes.
    Biochemical and biophysical research communications, 2001, Aug-03, Volume: 285, Issue:5

    Topics: Aging; Arginine; Biomarkers; Calibration; Chromatography, Liquid; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Middle Aged; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization

2001
Sensitivity and specificity of six tests for the diagnosis of adult GH deficiency.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:5

    Topics: Adult; Aged; Aging; Arginine; Body Mass Index; Diagnostic Techniques, Endocrine; Drug Combinations; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Levodopa; Male; Metabolic Diseases; Middle Aged; Sensitivity and Specificity; Sex Characteristics; Stimulation, Chemical

2002
Effect of normal aging on the prolactin response to graded doses of sulpiride and to arginine.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:5-6

    Topics: Adolescent; Adult; Aged; Aging; Arginine; Humans; Male; Prolactin; Stimulation, Chemical; Sulpiride; Time Factors

1985

Other Studies

417 other study(ies) available for arginine and Aging

ArticleYear
Swimming exercise with L-arginine coated nanoparticles supplementation upregulated HAND2 and TBX5 expression in the cardiomyocytes of aging male rats.
    Biogerontology, 2022, Volume: 23, Issue:4

    Topics: Aging; Animals; Arginine; Dietary Supplements; Humans; Male; Myocytes, Cardiac; Nanoparticles; Physical Conditioning, Animal; Rats; Rats, Wistar; RNA, Messenger; Swimming

2022
Swimming exercise and nano-l-arginine supplementation improve oxidative capacity and some autophagy-related genes in the soleus muscle of aging rats.
    Gene, 2023, Jan-20, Volume: 850

    Topics: Aging; Animals; Antioxidants; Arginine; Autophagy; Autophagy-Related Proteins; Chitosan; Dietary Supplements; Eosine Yellowish-(YS); Hematoxylin; Male; Muscle, Skeletal; Oxidative Stress; Physical Conditioning, Animal; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reactive Oxygen Species; Swimming

2023
Impairments of intestinal arginine and NO metabolisms trigger aging-associated intestinal barrier dysfunction and 'inflammaging'.
    Redox biology, 2022, Volume: 58

    Topics: Aging; Animals; Arginase; Arginine; Endotoxemia; Intestines; Mice; Nitric Oxide

2022
Ageing and endothelium-mediated vascular dysfunction: the role of the NADPH oxidases.
    The Journal of physiology, 2023, Volume: 601, Issue:3

    Topics: Acetylcholine; Aging; Arginine; Endothelium, Vascular; Humans; Middle Aged; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Vascular Diseases

2023
Glucose 6-P Dehydrogenase Overexpression Improves Aging-Induced Endothelial Dysfunction in Aorta from Mice: Role of Arginase II.
    International journal of molecular sciences, 2023, Feb-11, Volume: 24, Issue:4

    Topics: Aging; Animals; Aorta; Arginase; Arginine; Endothelium, Vascular; Glucose; Glucosephosphate Dehydrogenase; Male; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Vascular Diseases

2023
L-arginine supplementation minimizes aging-induced changes in the sperm chromatin of roosters.
    Poultry science, 2023, Volume: 102, Issue:8

    Topics: Aging; Animals; Arginine; Chickens; Chromatin; Diet; Dietary Supplements; Male; Semen; Semen Analysis; Sperm Motility; Spermatozoa

2023
Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats.
    Journal of veterinary internal medicine, 2019, Volume: 33, Issue:6

    Topics: Aging; Animals; Arginine; Biomarkers; Cats; Cross-Sectional Studies; Female; Fibroblast Growth Factors; Male; Reference Values

2019
ADMA as a possible marker of endothelial damage. A study in young asymptomatic patients with cerebral small vessel disease.
    Scientific reports, 2019, 10-02, Volume: 9, Issue:1

    Topics: Adult; Aged; Aging; Arginine; Biomarkers; Brain; Cerebral Small Vessel Diseases; Cognitive Dysfunction; Endothelial Cells; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Stroke

2019
Combination of exercise training and L-arginine reverses aging process through suppression of oxidative stress, inflammation, and apoptosis in the rat heart.
    Pflugers Archiv : European journal of physiology, 2020, Volume: 472, Issue:2

    Topics: Aging; Animals; Apoptosis; Arginine; Fibrosis; Heart; HSP70 Heat-Shock Proteins; Interleukins; Male; Myocardium; Oxidative Stress; Physical Conditioning, Animal; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha

2020
Developmental changes in the utilization of citrulline by neonatal pigs.
    American journal of physiology. Renal physiology, 2020, 01-01, Volume: 318, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Arginine; Citrulline; Female; Kidney; Male; Swine

2020
Effect of aging on the availability of amino acids from an immune-enhancing diet (IED) after a surgical stress in rats.
    Clinical nutrition (Edinburgh, Scotland), 2020, Volume: 39, Issue:9

    Topics: Aging; Amino Acids; Animals; Arginine; Biological Availability; Enteral Nutrition; Immunity; Male; Models, Animal; Postoperative Care; Rats; Rats, Sprague-Dawley; Stress, Physiological; Surgical Procedures, Operative

2020
[Prevention of the progression of atherosclerosis and aging through nitric oxide (NO)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2020, Volume: 155, Issue:2

    Topics: Aging; Animals; Arginine; Atherosclerosis; Citrulline; Humans; Nitric Oxide; Nitric Oxide Synthase; Vasodilation

2020
Mass spectrometric quantitation of AGEs and enzymatic crosslinks in human cancellous bone.
    Scientific reports, 2020, 11-02, Volume: 10, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Bone and Bones; Bone Diseases; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Mass Spectrometry; Ornithine; Sex Characteristics; Tartrate-Resistant Acid Phosphatase

2020
Arginine site 264 in murine estrogen receptor-α is dispensable for the regulation of the skeleton.
    American journal of physiology. Endocrinology and metabolism, 2021, 01-01, Volume: 320, Issue:1

    Topics: Absorptiometry, Photon; Aging; Animals; Arginine; Bone and Bones; Bone Density; Endothelium; Estrogen Receptor alpha; Estrogens; Female; Methylation; Mice; Organ Size; Ovariectomy; Spine; Tibia; Tomography, X-Ray Computed

2021
Reference values for bone metabolism in a Japanese cohort survey randomly sampled from a basic elderly resident registry.
    Scientific reports, 2021, 04-09, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Arginine; Biomarkers; Bone Density; Bone Resorption; Cohort Studies; Female; Femur Neck; Hip; Humans; Japan; Lysine; Male; Middle Aged; Osteoporosis; Reference Values; Registries; Tartrate-Resistant Acid Phosphatase; Vitamin D

2021
Biomarkers representing key aging-related biological pathways are associated with subclinical atherosclerosis and all-cause mortality: The Framingham Study.
    PloS one, 2021, Volume: 16, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Carotid Intima-Media Thickness; Creatinine; Cross-Sectional Studies; Endothelial Cells; Female; Humans; Insulin-Like Growth Factor I; Isoprostanes; Male; Middle Aged; Oxidative Stress; Prospective Studies; Telomere Homeostasis; Telomere Shortening

2021
Common Muscle Metabolic Signatures Highlight Arginine and Lysine Metabolism as Potential Therapeutic Targets to Combat Unhealthy Aging.
    International journal of molecular sciences, 2021, Jul-26, Volume: 22, Issue:15

    Topics: Aging; Animals; Arginine; Lysine; Male; Mice; Muscle, Skeletal; Oxidative Stress; Signal Transduction

2021
Age-Specific Characteristics of CO-Mediated Reaction of the Pial Arteries of Various Diameters in Rats.
    Bulletin of experimental biology and medicine, 2017, Volume: 162, Issue:5

    Topics: Aging; Animals; Arginine; Carbon Monoxide; Cerebral Arteries; Hemin; Male; NG-Nitroarginine Methyl Ester; Protoporphyrins; Rats, Wistar; Signal Transduction; Vasodilation

2017
Do the accelerating actions of tianeptine and l-arginine on cortical spreading depression interact? An electrophysiological analysis in young and adult rats.
    Neuroscience letters, 2017, 05-22, Volume: 650

    Topics: Aging; Animals; Arginine; Brain; Brain Mapping; Cortical Spreading Depression; Dose-Response Relationship, Drug; Drug Combinations; Female; Rats, Wistar; Thiazepines

2017
Arginine CGA codons as a source of nonsense mutations: a possible role in multivariant gene expression, control of mRNA quality, and aging.
    Molecular genetics and genomics : MGG, 2017, Volume: 292, Issue:5

    Topics: Aging; Alternative Splicing; Arginine; Catalase; Codon, Nonsense; DNA Methylation; Gene Expression; Glutamine; Humans; Nonsense Mediated mRNA Decay; RNA, Messenger; Selenocysteine; Selenoproteins

2017
Dimethylarginine Dimethylaminohydrolase 1 Deficiency Induces the Epithelial to Mesenchymal Transition in Renal Proximal Tubular Epithelial Cells and Exacerbates Kidney Damage in Aged and Diabetic Mice.
    Antioxidants & redox signaling, 2017, Dec-01, Volume: 27, Issue:16

    Topics: Aging; Aldosterone; Amidohydrolases; Animals; Arginine; Cell Line; Creatinine; Diabetes Mellitus, Experimental; Disease Models, Animal; Epithelial Cells; Epithelial-Mesenchymal Transition; Fibrosis; Gene Knockout Techniques; Humans; Kidney Diseases; Kidney Tubules, Proximal; Mice

2017
Peptide YY induces characteristic meal patterns of aged mice.
    Hormones and behavior, 2017, Volume: 96

    Topics: Aging; Animals; Appetite; Arginine; Benzazepines; Eating; Feeding Behavior; Male; Mice; Mice, Inbred C57BL; Peptide YY; Receptors, Neuropeptide Y

2017
Cognitive enhancement in old dogs from dietary supplementation with a nutrient blend containing arginine, antioxidants, B vitamins and fish oil.
    The British journal of nutrition, 2018, Volume: 119, Issue:3

    Topics: Aging; alpha-Tocopherol; Animals; Arginine; Cognition; Cognitive Dysfunction; Diet; Dietary Supplements; Discrimination Learning; Docosahexaenoic Acids; Dog Diseases; Dogs; Eicosapentaenoic Acid; Female; Fish Oils; Learning; Male; Nootropic Agents; Vitamin B Complex

2018
Effects of Aging and Tocotrienol-Rich Fraction Supplementation on Brain Arginine Metabolism in Rats.
    Oxidative medicine and cellular longevity, 2017, Volume: 2017

    Topics: Aging; Amino Acids; Animals; Antioxidants; Arginine; Brain; Dietary Supplements; Male; Polyamines; Rats; Rats, Wistar; Tocotrienols

2017
Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age.
    Bone, 2018, Volume: 110

    Topics: Aging; Animals; Arginine; Bone Density; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Femur; Fractures, Bone; Lysine; Male; Mice; Spectrum Analysis, Raman; X-Ray Microtomography

2018
In vitro effects of hydroxyapatite containing toothpastes on dentin permeability after multiple applications and ageing.
    Scientific reports, 2018, 03-20, Volume: 8, Issue:1

    Topics: Aging; Animals; Arginine; Calcium Carbonate; Cattle; Dentin; Dentin Permeability; Dentin Sensitivity; Durapatite; Fluorides; Humans; Nitrates; Potassium Compounds; Saliva; Sodium Fluoride; Toothbrushing; Toothpastes

2018
Reaction time in healthy elderly is associated with chronic low-grade inflammation and advanced glycation end product.
    Experimental gerontology, 2018, 07-15, Volume: 108

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Electromyography; Female; Glycation End Products, Advanced; Humans; Inflammation; Isometric Contraction; Linear Models; Lysine; Male; Muscle Weakness; Muscle, Skeletal; Reaction Time; Sarcopenia; Sex Factors

2018
Age-dependent effects of homocysteine and dimethylarginines on cardiovascular mortality in claudicant patients with lower extremity arterial disease.
    Heart and vessels, 2018, Volume: 33, Issue:12

    Topics: Aged; Aging; Arginine; Austria; Cardiovascular Diseases; Female; Homocysteine; Humans; Incidence; Intermittent Claudication; Lower Extremity; Male; Prospective Studies; Risk Factors; Survival Rate

2018
Soybean-Derived Glycine-Arginine Dipeptide Administration Promotes Neurotrophic Factor Expression in the Mouse Brain.
    Journal of agricultural and food chemistry, 2018, Aug-01, Volume: 66, Issue:30

    Topics: Aging; Animals; Arginine; Brain; Brain-Derived Neurotrophic Factor; Dipeptides; Female; Glycine; Glycine max; Hippocampus; Humans; Male; Memory; Mice; Mice, Inbred C57BL; Neurogenesis; Plant Extracts

2018
Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018, 08-29, Volume: 38, Issue:35

    Topics: Aging; Amino Acid Sequence; Animals; Arginine; Cell Line; Cyclic AMP Response Element-Binding Protein; DNA Breaks, Double-Stranded; DNA Damage; DNA Repair; Isometric Contraction; Male; Mice; Mice, Knockout; Mice, Transgenic; Motor Neurons; Muscle Cells; Neuromuscular Junction; Protein-Arginine N-Methyltransferases; Recombinant Fusion Proteins; Reflex, Abnormal; RNA Interference; RNA, Small Interfering; Rotarod Performance Test; Spinal Cord

2018
Differences in non-enzymatic glycation products in human dentine and clavicle: changes with aging.
    International journal of legal medicine, 2018, Volume: 132, Issue:6

    Topics: Adolescent; Adult; Age Determination by Skeleton; Age Determination by Teeth; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Clavicle; Dentin; Female; Forensic Sciences; Humans; Lysine; Male; Middle Aged; Young Adult

2018
Objective Colorimetric Evaluation of Aging-related Articular Cartilage Degeneration.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2018, Volume: 85, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Analysis of Variance; Arginine; Cartilage, Articular; Chromatography, High Pressure Liquid; Color; Colorimetry; Female; Glycation End Products, Advanced; Humans; Hydroxyproline; Lysine; Male; Middle Aged; Osteoarthritis; Prospective Studies

2018
Arginase Inhibition Improves Endothelial Function in an Age-Dependent Manner in Healthy Elderly Humans.
    Rejuvenation research, 2019, Volume: 22, Issue:5

    Topics: Aged; Aging; Arginase; Arginine; Endothelium, Vascular; Enzyme Inhibitors; Female; Healthy Volunteers; Humans; Male; Middle Aged; Nitric Oxide; Vasodilation

2019
Age estimation based on different molecular clocks in several tissues and a multivariate approach: an explorative study.
    International journal of legal medicine, 2020, Volume: 134, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; D-Aspartic Acid; Epiglottis; Female; Forensic Medicine; Humans; Infant; Intervertebral Disc; Lysine; Male; Middle Aged; Models, Statistical; Multivariate Analysis; Young Adult

2020
Decline of popliteal artery flow-mediated dilation with aging and possible involvement of asymmetric dimethylarginine in healthy men.
    Journal of medical ultrasonics (2001), 2019, Volume: 46, Issue:4

    Topics: Adult; Age Factors; Aging; Arginine; Brachial Artery; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Popliteal Artery; Reference Values; Sex Factors; Vasodilation

2019
Age-Dependent Oxidative Stress Elevates Arginase 1 and Uncoupled Nitric Oxide Synthesis in Skeletal Muscle of Aged Mice.
    Oxidative medicine and cellular longevity, 2019, Volume: 2019

    Topics: Aging; Animals; Arginase; Arginine; Endothelium, Vascular; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Nitric Oxide; Oxidative Stress

2019
The association of urinary pentosidine levels with the prevalence of osteoporotic fractures in postmenopausal women.
    Journal of bone and mineral metabolism, 2019, Volume: 37, Issue:6

    Topics: Aged; Aging; Arginine; Cohort Studies; Cross-Sectional Studies; Female; Humans; Logistic Models; Lysine; Middle Aged; Multivariate Analysis; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Prevalence

2019
Differences in non-enzymatic glycation and collagen cross-links between human cortical and cancellous bone.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Collagen; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Specimen Handling; Tibia; Tissue Culture Techniques; Young Adult

2013
Regional variations and age-related changes in arginine metabolism in the rat brain stem and spinal cord.
    Neuroscience, 2013, Nov-12, Volume: 252

    Topics: Aging; Animals; Arginine; Blotting, Western; Brain Stem; Male; Rats; Rats, Sprague-Dawley; Spinal Cord

2013
Age-related changes in ADMA-DDAH-NO pathway in rat liver subjected to partial ischemia followed by global reperfusion.
    Experimental gerontology, 2014, Volume: 50

    Topics: Aging; Amidohydrolases; Animals; Arginine; Liver; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reperfusion Injury; Signal Transduction; Transaminases

2014
Exercise performance and peripheral vascular insufficiency improve with AMPK activation in high-fat diet-fed mice.
    American journal of physiology. Heart and circulatory physiology, 2014, Apr-15, Volume: 306, Issue:8

    Topics: Aging; AMP-Activated Protein Kinases; Animals; Apolipoproteins E; Arginine; Cilostazol; Diet, High-Fat; Disease Models, Animal; Enzyme Activation; Enzyme Activators; Humans; Intermittent Claudication; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Fatigue; Muscle, Skeletal; Nitric Oxide Synthase Type III; Obesity; Peripheral Vascular Diseases; Phosphodiesterase 3 Inhibitors; Physical Exertion; Tetrazoles; Vasodilator Agents

2014
Potential role of pentosidine on susceptibility to small airway closure in elderly and smoking asthma.
    Respiratory medicine, 2014, Volume: 108, Issue:5

    Topics: Adult; Aged; Aging; Arginine; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Bronchoconstrictor Agents; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Lysine; Male; Methacholine Chloride; Middle Aged; Respiratory Function Tests; Smoking; Sputum; Vital Capacity; Young Adult

2014
Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice.
    Scientific reports, 2014, Apr-01, Volume: 4

    Topics: Administration, Oral; Aging; Animals; Arginine; Feces; Female; Intestines; Longevity; Male; Metabolome; Metabolomics; Mice; Microbiota; Polyamines; Probiotics; Putrescine; Quality of Life; Time Factors; Up-Regulation

2014
Altered arginine metabolism in Alzheimer's disease brains.
    Neurobiology of aging, 2014, Volume: 35, Issue:9

    Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Arginase; Arginine; Cerebellum; Disease Progression; Female; Hippocampus; Humans; Male; Middle Aged; Nitric Oxide Synthase; Organ Specificity; Prefrontal Cortex

2014
L-arginine and tetrahydrobiopterin, but not sodium nitrite partially restored erectile dysfunction in aged rats.
    The aging male : the official journal of the International Society for the Study of the Aging Male, 2014, Volume: 17, Issue:4

    Topics: Aging; Animals; Arginine; Biopterins; Dose-Response Relationship, Drug; Erectile Dysfunction; Male; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Penile Erection; Penis; Rats, Wistar; Sodium Nitrite

2014
Aging of the nitric oxide system: are we as old as our NO?
    Journal of the American Heart Association, 2014, Aug-18, Volume: 3, Issue:4

    Topics: Aged; Aging; Arginine; Blood Platelets; Cardiovascular Diseases; Cohort Studies; Female; Follow-Up Studies; Humans; Male; Middle Aged; Nitric Oxide; Platelet Aggregation; Prospective Studies

2014
Asymmetric dimethylarginine attenuates the association of melatonin secretion with night-time blood pressure and dipping in elderly individuals.
    Circulation journal : official journal of the Japanese Circulation Society, 2014, Volume: 78, Issue:12

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Blood Pressure; Body Mass Index; Circadian Rhythm; Cross-Sectional Studies; Diabetes Mellitus; Endothelium, Vascular; Female; Humans; Hypertension; Male; Melatonin; Nitric Oxide; Nitric Oxide Synthase Type III; Secretory Rate; Smoking

2014
Association of advanced age with concentrations of uraemic toxins in CKD.
    Journal of nephrology, 2016, Volume: 29, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; beta 2-Microglobulin; Biomarkers; Blood Urea Nitrogen; Creatinine; Female; Furans; Humans; Male; Middle Aged; Multivariate Analysis; Propionates; Renal Dialysis; Renal Insufficiency, Chronic; Uremia

2016
Senescence marker protein-30 deficiency impairs angiogenesis under ischemia.
    Free radical biology & medicine, 2016, Volume: 94

    Topics: Aging; Animals; Apoptosis; Arginine; Calcium-Binding Proteins; Glutathione; Humans; Intracellular Signaling Peptides and Proteins; Ischemia; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Superoxides; Vascular Endothelial Growth Factor A

2016
Age-associated metabolic dysregulation in bone marrow-derived macrophages stimulated with lipopolysaccharide.
    Scientific reports, 2016, Mar-04, Volume: 6

    Topics: Aging; Animals; Arginine; Cells, Cultured; gamma-Aminobutyric Acid; Glycolysis; Inflammation; Lipopolysaccharides; Macrophage Activation; Macrophages; Metabolic Diseases; Mice; Mice, Inbred C57BL; Oxidative Phosphorylation; Succinic Acid

2016
Ageing/Menopausal Status in Healthy Women and Ageing in Healthy Men Differently Affect Cardiometabolic Parameters.
    International journal of medical sciences, 2016, Volume: 13, Issue:2

    Topics: Adult; Aging; Arginine; Blood; Body Weight; Female; Humans; Interleukin-6; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Postmenopause; Premenopause; Protein Carbonylation; Risk Factors; Triglycerides; Tumor Necrosis Factor-alpha

2016
FACTORS ASSOCIATED WITH PENTOSIDINE ACCUMULATION IN THE HUMAN VITREOUS.
    Retina (Philadelphia, Pa.), 2017, Volume: 37, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Humans; Lysine; Male; Middle Aged; Pseudophakia; Regression Analysis; Sex Factors; Vitreous Body; Vitreous Detachment; Young Adult

2017
Isoaspartic acid is present at specific sites in myelin basic protein from multiple sclerosis patients: could this represent a trigger for disease onset?
    Acta neuropathologica communications, 2016, 08-12, Volume: 4, Issue:1

    Topics: Adult; Aged; Aging; Arginine; Aspartic Acid; Cerebellum; Glutamine; Humans; Isoaspartic Acid; Mass Spectrometry; Middle Aged; Models, Molecular; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Relapsing-Remitting; Myelin Basic Protein; Protein Processing, Post-Translational; Proteolysis

2016
A-to-I RNA editing of the IGFBP7 transcript increases during aging in porcine brain tissues.
    Biochemical and biophysical research communications, 2016, Oct-21, Volume: 479, Issue:3

    Topics: Aging; Amino Acid Sequence; Animals; Arginine; Binding Sites; Brain; Brain Mapping; Cerebellum; Chromosome Mapping; Female; Frontal Lobe; Gene Expression Profiling; Gene Expression Regulation; Humans; Insulin-Like Growth Factor Binding Proteins; Lung; Lysine; Methylation; Mice; RNA Editing; RNA-Binding Proteins; RNA, Messenger; Sulfates; Swine

2016
Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis.
    Respiratory research, 2016, 11-05, Volume: 17, Issue:1

    Topics: Aged; Aging; Alveolar Epithelial Cells; Antigens, Neoplasm; Arginine; Epithelial Cells; Extracellular Matrix Proteins; Female; Fibroblasts; Glycation End Products, Advanced; Humans; Idiopathic Pulmonary Fibrosis; Immunohistochemistry; Lung; Lysine; Male; Middle Aged; Mitogen-Activated Protein Kinases; Signal Transduction

2016
Involvement of DDAH/ADMA/NOS/cGMP and COX-2/PTGIS/cAMP Pathways in Human Tissue Kallikrein 1 Protecting Erectile Function in Aged Rats.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Aging; Amidohydrolases; Animals; Arginine; Cyclic AMP; Cyclic GMP; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Erectile Dysfunction; Humans; Intramolecular Oxidoreductases; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Penis; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Recombinant Proteins; RNA, Messenger; Signal Transduction; Tissue Kallikreins

2017
Effects of a chronic l-arginine supplementation on the arginase pathway in aged rats.
    Experimental gerontology, 2017, Volume: 90

    Topics: Aging; Animals; Arginase; Arginine; Blood Pressure; Dietary Supplements; Heart Rate; Male; Nitric Oxide; Ornithine; Rats; Rats, Wistar

2017
Carotid Plaque Score and Risk of Cardiovascular Mortality in the Oldest Old: Results from the TOOTH Study.
    Journal of atherosclerosis and thrombosis, 2018, Jan-01, Volume: 25, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Cardiovascular Diseases; Carotid Stenosis; Cohort Studies; Female; Humans; Japan; Kaplan-Meier Estimate; Male; Multivariate Analysis; Proportional Hazards Models; Risk Factors; Sensitivity and Specificity; Treatment Outcome

2018
Further studies of the effects of aging on arginine metabolites in the rat vestibular nucleus and cerebellum.
    Neuroscience, 2017, 04-21, Volume: 348

    Topics: Aging; Animals; Arginine; Cerebellum; Citrulline; Glutamic Acid; Male; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley; Vestibular Nuclei

2017
Age related differences in stress-induced neurobehavioral responses in rats: modulation by antioxidants and nitrergic agents.
    Behavioural brain research, 2008, Dec-01, Volume: 194, Issue:1

    Topics: Aging; alpha-Tocopherol; Animals; Antioxidants; Arginine; Behavior, Animal; Catalase; Enzyme Inhibitors; Exploratory Behavior; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; NG-Nitroarginine Methyl Ester; Nitrates; Nitrites; Rats; Rats, Wistar; Restraint, Physical; Stress, Psychological; Superoxide Dismutase

2008
Early malnutrition, but not age, modulates in the rat the L-Arginine facilitating effect on cortical spreading depression.
    Neuroscience letters, 2008, Dec-05, Volume: 447, Issue:1

    Topics: Aging; Animals; Arginine; Cortical Spreading Depression; Electroencephalography; Malnutrition; Rats

2008
Effect of amino acids on cell proliferation and protein p53 expression in organotypic culture of lymphoid tissue from neonatal rats.
    Cell biology international, 2008, Volume: 32, Issue:12

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Asparagine; Cell Differentiation; Cell Proliferation; Down-Regulation; Glutamic Acid; Lymphocyte Activation; Lymphoid Tissue; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen; T-Lymphocytes; Tumor Suppressor Protein p53; Up-Regulation

2008
Sexual dimorphism in glomerular arginine transport affects nitric oxide generation in old male rats.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:1

    Topics: Aging; Animals; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Cyclic GMP; Female; Kidney Glomerulus; Male; Models, Animal; Nitric Oxide; Nitric Oxide Synthase Type III; Protein Kinase C-alpha; Rats; Rats, Wistar; Sex Characteristics

2009
Urinary levels of pentosidine and the risk of fracture in postmenopausal women: the OFELY study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2010, Volume: 21, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone Density; Epidemiologic Methods; Female; Hip Joint; Humans; Lumbar Vertebrae; Lysine; Middle Aged; Osteoporotic Fractures; Postmenopause; Spinal Fractures

2010
Pentosidine accumulates in the aging vitreous body: a gender effect.
    Experimental eye research, 2009, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Ciliary Body; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Menopause; Middle Aged; Sex Characteristics; Vitreous Body; Young Adult

2009
Association between dietary protein and change in body composition among children (EYHS).
    Clinical nutrition (Edinburgh, Scotland), 2009, Volume: 28, Issue:6

    Topics: Adolescent; Aging; Algorithms; Arginine; Body Composition; Body Mass Index; Child; Dietary Proteins; Female; Health Surveys; Humans; Lysine; Male; Motor Activity; Obesity; Puberty; Sex Characteristics; Social Class

2009
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men.
    Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 107, Issue:3

    Topics: Adult; Aged; Aging; Amino Acids; Arginine; Arm; Biomechanical Phenomena; Biopsy; Collagen; Glycation End Products, Advanced; Humans; Hydroxyproline; Knee; Lysine; Male; Movement; Muscle, Skeletal; Patellar Ligament; Protein-Lysine 6-Oxidase

2009
Correlates of arterial stiffness in an ageing population: role of asymmetric dimethylarginine.
    Pharmacological research, 2009, Volume: 60, Issue:6

    Topics: Aged; Aging; Arginine; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Vascular Resistance

2009
Protective effect of selenoarginine against oxidative stress in D-galactose-induced aging mice.
    Bioscience, biotechnology, and biochemistry, 2009, Volume: 73, Issue:7

    Topics: Aging; Animals; Antioxidants; Arginine; Female; Galactose; Glutathione Peroxidase; Male; Malondialdehyde; Mice; Organoselenium Compounds; Oxidative Stress; Superoxide Dismutase

2009
Age-related changes in arginine and its metabolites in memory-associated brain structures.
    Neuroscience, 2009, Dec-01, Volume: 164, Issue:2

    Topics: Aging; Analysis of Variance; Animals; Arginase; Arginine; Brain; Citrulline; gamma-Aminobutyric Acid; Glutamic Acid; Male; Memory; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley

2009
Red wine decreases asymmetric dimethylarginine via SIRT1 induction in human endothelial cells.
    Biochemical and biophysical research communications, 2009, Dec-18, Volume: 390, Issue:3

    Topics: Age Factors; Aging; Amidohydrolases; Arginine; Cell Survival; Cells, Cultured; Cellular Senescence; Endothelial Cells; Humans; Methyltransferases; Nitric Oxide Synthase; Sirtuin 1; Up-Regulation; Wine

2009
Aortic arginine transport is attenuated, through post-translational modulation of CAT-1 by PKCalpha, in old male rats.
    Vascular medicine (London, England), 2010, Volume: 15, Issue:1

    Topics: Age Factors; Aging; alpha-Tocopherol; Animals; Aorta; Arginine; Biological Transport; Cationic Amino Acid Transporter 1; Down-Regulation; Female; Male; Nitric Oxide Synthase Type III; Phosphorylation; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Wistar; Up-Regulation

2010
[Management of adolescents with childhood onset growth hormone deficiency in the transition--results of a field based study in Germany].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:50

    Topics: Adolescent; Adult; Aging; Arginine; Body Height; Child; Germany; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Physician-Patient Relations

2009
Relationship of asymmetric dimethylarginine and homocysteine to vascular aging in systemic lupus erythematosus patients.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:6

    Topics: Adult; Aging; Arginine; Carotid Arteries; Female; Homocysteine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Multivariate Analysis; Patient Selection; Prognosis; Severity of Illness Index; Vascular Diseases

2010
NPY mediates ATP-induced neuroproliferation in adult mouse olfactory epithelium.
    Neurobiology of disease, 2010, Volume: 38, Issue:3

    Topics: Adenosine Triphosphate; Aging; Animals; Arginine; Cell Proliferation; Dose-Response Relationship, Drug; Male; Mice; Models, Neurological; Neurogenesis; Neuropeptide Y; Olfactory Mucosa; Purinergic Antagonists; Pyridoxal Phosphate; Receptors, Neuropeptide Y; Receptors, Purinergic; Sensory Receptor Cells

2010
Decrease in asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in cerebrospinal fluid during elderly aging and in patients with sporadic form of amyotrophic lateral sclerosis.
    Neuro-Signals, 2010, Volume: 18, Issue:1

    Topics: Aged; Aging; Amyotrophic Lateral Sclerosis; Analysis of Variance; Anthracenes; Arginine; Case-Control Studies; Female; Humans; Male; Middle Aged; Propane; Statistics, Nonparametric

2010
Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A.
    Brain : a journal of neurology, 2010, Volume: 133, Issue:Pt 5

    Topics: Aging; Animals; Arginine; Axons; Charcot-Marie-Tooth Disease; DNA, Complementary; Glutamine; GTP Phosphohydrolases; Humans; Membrane Transport Proteins; Mice; Mice, Transgenic; Microscopy, Electron; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Proteins; Mutation; Nerve Fibers, Myelinated; Neurons; Peripheral Nerves; Phenotype; Sciatic Nerve

2010
Charcot-Marie-Tooth type 1A disease caused by a novel Ser112Arg mutation in the PMP22 gene, coexisting with a slowly progressive hearing impairment.
    Journal of applied genetics, 2010, Volume: 51, Issue:2

    Topics: Adolescent; Adult; Age of Onset; Aging; Amino Acid Sequence; Amino Acid Substitution; Arginine; Audiometry; Charcot-Marie-Tooth Disease; Child; Child, Preschool; Conserved Sequence; Hearing Disorders; Humans; Male; Molecular Sequence Data; Myelin Proteins; Phenotype; Serine

2010
A multivariate analysis of the effects of aging on glutamate, GABA and arginine metabolites in the rat vestibular nucleus.
    Hearing research, 2010, Oct-01, Volume: 269, Issue:1-2

    Topics: Aging; Animals; Arginine; Cerebellum; Cluster Analysis; gamma-Aminobutyric Acid; Glutamic Acid; Male; Models, Animal; Multivariate Analysis; Rats; Rats, Sprague-Dawley; Spermidine; Spermine; Vestibular Nuclei

2010
Quantitative biometric phenotype analysis in mouse lenses.
    Molecular vision, 2010, Jun-08, Volume: 16

    Topics: Aging; alpha-Crystallin A Chain; Animals; Arginine; Biometry; Cataract; Cysteine; Eye Abnormalities; Genotype; Heterozygote; Homozygote; Image Processing, Computer-Assisted; Lens, Crystalline; Mice; Mice, Knockout; Mice, Transgenic; Mutation; Organ Size; Phenotype; Solubility

2010
Potential roles of pentosidine in age-related and disease-related impairment of pulmonary functions in patients with asthma.
    The Journal of allergy and clinical immunology, 2011, Volume: 127, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Asthma; Cross-Linking Reagents; Female; Humans; Lysine; Male; Middle Aged; Respiratory Function Tests; Sputum; Young Adult

2011
Advanced glycation end-products accumulation compromises embryonic development and achievement of pregnancy by assisted reproductive technology.
    Human reproduction (Oxford, England), 2011, Volume: 26, Issue:3

    Topics: Aging; Arginine; Embryo Implantation; Embryonic Development; Female; Fertilization in Vitro; Follicle Stimulating Hormone; Follicular Fluid; Glycation End Products, Advanced; Humans; Infertility; Lysine; Ovulation Induction; Pregnancy; Pregnancy Rate; Reproductive Techniques, Assisted; Retrospective Studies

2011
The induction of macrophage hemeoxygenase-1 is protective during acute kidney injury in aging mice.
    Kidney international, 2011, Volume: 79, Issue:9

    Topics: Acute Kidney Injury; Aging; Animals; Arginine; Cells, Cultured; Heme; Heme Oxygenase-1; Kidney; Macrophages; Membrane Proteins; Mice; Reperfusion Injury

2011
Atheroprotective effects of dietary L-arginine increase with age in cholesterol-fed rabbits.
    The British journal of nutrition, 2011, Volume: 105, Issue:10

    Topics: Aging; Animals; Arginine; Atherosclerosis; Cholesterol, Dietary; Diet; Rabbits

2011
Age differences in the relation between ACTN3 R577X polymorphism and thigh-muscle cross-sectional area in women.
    Genetic testing and molecular biomarkers, 2011, Volume: 15, Issue:9

    Topics: Actinin; Age Factors; Aged; Aging; Amino Acid Substitution; Anatomy, Cross-Sectional; Arginine; Asian People; Body Composition; Female; Genetic Association Studies; Humans; Middle Aged; Muscles; Polymorphism, Single Nucleotide; Sex Factors; Thigh

2011
Age-related modification of antioxidant enzyme activities in relation to cardiovascular risk factors.
    European journal of clinical investigation, 2012, Volume: 42, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Apolipoproteins A; Arginine; Cardiovascular Diseases; Catalase; Enzyme-Linked Immunosorbent Assay; Female; Fetuins; Glutathione Peroxidase; Humans; Lipid Peroxidation; Lipoproteins; Lipoproteins, LDL; Male; Oxidation-Reduction; Oxidative Stress; Risk Factors; Statistics as Topic; Superoxide Dismutase

2012
Differential effects of physical exercise and L-arginine on cortical spreading depression in developing rats.
    Nutritional neuroscience, 2011, Volume: 14, Issue:3

    Topics: Aging; Animals; Arginine; Body Weight; Brain; Cortical Spreading Depression; Dose-Response Relationship, Drug; Histidine; Male; Motor Activity; Organ Size; Rats; Rats, Wistar

2011
Effect of exogenous l-arginine and ageing on NO and ET-1 in penile tissue of rat.
    Andrologia, 2011, Volume: 43, Issue:5

    Topics: Aging; Animals; Arginine; Cyclic GMP; Endothelin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Penis; Rats; Rats, Wistar

2011
Computed tomography detects changes in contrast agent diffusion after collagen cross-linking typical to natural aging of articular cartilage.
    Osteoarthritis and cartilage, 2011, Volume: 19, Issue:10

    Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Case-Control Studies; Cattle; Collagen; Contrast Media; Hindlimb; Ioxaglic Acid; Lysine; Patella; Tetroses; Tomography, X-Ray Computed

2011
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice.
    Molecular vision, 2011, Volume: 17

    Topics: Acetylcysteine; Administration, Topical; Aging; Animals; Arginine; Ascorbic Acid; Biological Transport, Active; Cataract; Crystallins; Gene Knock-In Techniques; Glycation End Products, Advanced; Guanidines; Humans; Lens, Crystalline; Mass Spectrometry; Mice; Mice, Transgenic; Ophthalmic Solutions; Penicillamine; Rabbits; Sodium-Coupled Vitamin C Transporters; Spectrometry, Fluorescence

2011
Advanced glycation end product level, diabetes, and accelerated cognitive aging.
    Neurology, 2011, Oct-04, Volume: 77, Issue:14

    Topics: Aged; Aging; Arginine; Chi-Square Distribution; Cognition Disorders; Diabetes Mellitus; Female; Glycation End Products, Advanced; Humans; Longitudinal Studies; Lysine; Male; Mental Status Schedule; Neuropsychological Tests; Odds Ratio

2011
Features, causes and consequences of splanchnic sequestration of amino acid in old rats.
    PloS one, 2011, Volume: 6, Issue:11

    Topics: Age Factors; Aging; Amino Acids; Animals; Arginine; Intestinal Mucosa; Kupffer Cells; Liver; Lysine; Protein Biosynthesis; Rats; Viscera

2011
Advanced glycation end-products as markers of aging and longevity in the long-lived Ansell's mole-rat (Fukomys anselli).
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2012, Volume: 67, Issue:6

    Topics: Aging; Animals; Arginine; Biomarkers; Collagen; Female; Glycation End Products, Advanced; Longevity; Lysine; Male; Mole Rats; Skin

2012
In end stage osteoarthritis, cartilage tissue pentosidine levels are inversely related to parameters of cartilage damage.
    Osteoarthritis and cartilage, 2012, Volume: 20, Issue:3

    Topics: Aged; Aging; Arginine; Arthroplasty, Replacement, Knee; Biomarkers; Cartilage, Articular; Collagen; Female; Glycation End Products, Advanced; Humans; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis, Knee; Severity of Illness Index

2012
Aging affects L-arginine and its metabolites in memory-associated brain structures at the tissue and synaptoneurosome levels.
    Neuroscience, 2012, May-03, Volume: 209

    Topics: Aging; Animals; Arginine; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Chromatography, Liquid; Male; Mass Spectrometry; Memory; Rats; Rats, Sprague-Dawley; Synaptosomes

2012
Ageing in Werner syndrome.
    Bioscience trends, 2012, Volume: 6, Issue:1

    Topics: Adult; Aged, 80 and over; Aging; Arginine; Female; Health; Homocysteine; Humans; Lysine; Male; Middle Aged; Werner Syndrome

2012
Altered neuronal nitric oxide synthase in the aging vascular system: implications for estrogens therapy.
    Endocrinology, 2012, Volume: 153, Issue:8

    Topics: Aging; Animals; Aorta, Thoracic; Arginine; Blotting, Western; Estradiol; Female; In Vitro Techniques; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Ovariectomy; Rats; Rats, Sprague-Dawley; Superoxides; Tyrosine

2012
Ageing alters behavioural function and brain arginine metabolism in male Sprague-Dawley rats.
    Neuroscience, 2012, Dec-13, Volume: 226

    Topics: Aging; Animals; Anxiety; Arginase; Arginine; Behavior, Animal; Body Weight; Brain Chemistry; Chromatography, High Pressure Liquid; Cues; Male; Mass Spectrometry; Maze Learning; Memory; Motor Activity; Nitric Oxide Synthase; Orientation; Psychomotor Performance; Rats; Rats, Sprague-Dawley

2012
Impact of UCP1 and β3AR gene polymorphisms on age-related changes in brown adipose tissue and adiposity in humans.
    International journal of obesity (2005), 2013, Volume: 37, Issue:7

    Topics: Adipose Tissue, Brown; Adiposity; Adult; Aged; Aging; Arginine; Energy Metabolism; Female; Fluorodeoxyglucose F18; Healthy Volunteers; Humans; Ion Channels; Japan; Male; Middle Aged; Mitochondrial Proteins; Polymorphism, Single Nucleotide; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Adrenergic, beta-3; Thermogenesis; Tomography, X-Ray Computed; Tryptophan; Uncoupling Protein 1

2013
Dietary guanidino acetic acid is an efficacious replacement for arginine for young chicks.
    Poultry science, 2013, Volume: 92, Issue:1

    Topics: Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Diet; Glycine

2013
Transsulfuration pathway thiols and methylated arginines: the Hunter Community Study.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aging; Amidohydrolases; Arginine; Australia; C-Reactive Protein; Cardiovascular Diseases; Cohort Studies; Community Medicine; Cysteine; Dipeptides; Female; Glutathione; Homocysteine; Humans; Male; Middle Aged; Taurine

2013
Effect of dietary taurine and arginine supplementation on bone mineral density in growing female rats.
    Advances in experimental medicine and biology, 2013, Volume: 776

    Topics: Aging; Amino Acids; Animals; Arginine; Bone Density; Calcium; Creatinine; Dietary Supplements; Feeding Behavior; Female; Food; Phosphorus; Rats; Rats, Sprague-Dawley; Taurine; Weight Gain

2013
Role of nitric oxide on age-dependent alterations: investigation of electrophysiologic and biochemical parameters.
    The International journal of neuroscience, 2002, Volume: 112, Issue:3

    Topics: Aging; Animals; Antioxidants; Arginine; Brain; Enzyme Inhibitors; Evoked Potentials, Visual; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitrous Acid; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vitamin E

2002
Accumulation of imidazolone, pentosidine and N(epsilon)-(carboxymethyl)lysine in hippocampal CA4 pyramidal neurons of aged human brain.
    Pathology international, 2002, Volume: 52, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunohistochemistry; Lysine; Male; Middle Aged; Pyramidal Cells

2002
Unexpected carbonyl mobility in aminoketoses: the key to major Maillard crosslinks.
    Angewandte Chemie (International ed. in English), 2002, Mar-01, Volume: 41, Issue:5

    Topics: Aging; Amino Sugars; Arginine; Carbon Radioisotopes; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Radioactive Tracers

2002
Endothelium-dependent vasorelaxation and the expression of calcitonin gene-related peptide in aged rats.
    Neuropeptides, 2002, Volume: 36, Issue:6

    Topics: Aging; Animals; Arginine; Calcitonin Gene-Related Peptide; Endothelium, Vascular; Gene Expression; Male; Phenylephrine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Vasoconstrictor Agents; Vasodilation

2002
The nutritional status has no major role in the age-related reduction of IGF-I secretion.
    Journal of endocrinological investigation, 2002, Volume: 25, Issue:10 Suppl

    Topics: Aged; Aging; Arginine; Dehydroepiandrosterone Sulfate; Drug Combinations; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Middle Aged; Nutritional Status; Reference Values

2002
Activation and potentiation of the NO/cGMP pathway by NG-hydroxyl-L-arginine in rabbit corpus cavernosum under normoxic and hypoxic conditions and ageing.
    British journal of pharmacology, 2003, Volume: 138, Issue:1

    Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Hydroxyl Radical; Hypoxia; In Vitro Techniques; Male; Nitric Oxide; Penis; Rabbits; Vasodilation

2003
Asymmetric dimethylarginine, blood pressure, and renal perfusion in elderly subjects.
    Circulation, 2003, Apr-15, Volume: 107, Issue:14

    Topics: Adult; Aged; Aging; Arginine; Blood Pressure; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Male; Renal Circulation; Renal Plasma Flow, Effective

2003
Age-related changes in the protective effect of chronic administration of L-arginine on post-ischemic recovery of endothelial function.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2003, Volume: 23, Issue:4

    Topics: Aging; Animals; Arginine; Endothelium, Vascular; Male; Models, Animal; Muscle, Smooth, Vascular; Myocardial Reperfusion Injury; Nitric Oxide; Nitroglycerin; Perfusion; Rats; Rats, Sprague-Dawley; Serotonin; Vasodilator Agents

2003
Arginine need of heavy broiler males: applying the ideal protein concept.
    Poultry science, 2003, Volume: 82, Issue:3

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Dietary Proteins; Glycine max; Male; Nitrogen; Nutritional Requirements; Weight Gain; Zea mays

2003
Plasma pentosidine is associated with inflammation and malnutrition in end-stage renal disease patients starting on dialysis therapy.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Cardiovascular Diseases; Cohort Studies; Female; Glomerular Filtration Rate; Humans; Inflammation; Kidney Failure, Chronic; Lysine; Male; Mortality; Nutrition Disorders; Prognosis; Prospective Studies; Renal Dialysis; Survival Analysis

2003
The effect of caloric restriction on glycation and glycoxidation in skin collagen of nonhuman primates.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2003, Volume: 58, Issue:6

    Topics: Aging; Analysis of Variance; Animals; Arginine; Biomarkers; Body Weight; Chromatography, High Pressure Liquid; Collagen; Food Deprivation; Glucose; Glucose Tolerance Test; Glycation End Products, Advanced; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Regression Analysis; Saimiri; Skin

2003
Regional variations and age-related changes in nitric oxide synthase and arginase in the sub-regions of the hippocampus.
    Neuroscience, 2003, Volume: 119, Issue:3

    Topics: Aging; Animals; Arginase; Arginine; Dentate Gyrus; Down-Regulation; Hippocampus; Liver; Male; Memory Disorders; Nerve Degeneration; Neurons; Nitric Oxide; Nitric Oxide Synthase; Protein Isoforms; Rats; Rats, Sprague-Dawley; Up-Regulation; Urea

2003
Beta-cell capacity and insulin sensitivity in prepubertal children born small for gestational age: influence of body size during childhood.
    Diabetes, 2003, Volume: 52, Issue:7

    Topics: Aging; Arginine; Birth Weight; Body Constitution; Body Mass Index; Child; Female; Growth; Humans; Infant, Newborn; Infant, Small for Gestational Age; Insulin; Insulin Secretion; Islets of Langerhans; Male

2003
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
    Journal of neurochemistry, 1964, Volume: 11

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine

1964
[ARGINASE ACTIVITY DURING THE EMBRYONIC DEVELOPMENT OF THE ALBINO RAT (RATTUS NORWEGICUS)].
    Biologica (Santiago, Chile), 1963, Volume: 35

    Topics: Aging; Amniotic Fluid; Arginase; Arginine; Blood; Brain; Embryo, Mammalian; Embryo, Nonmammalian; Female; Liver; Ornithine; Placenta; Pregnancy; Proteins; Rats; Research; Urea

1963
[The modulating role of essential and non-essential amino acids in organotypic tissue culture in rats of different ages].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2003, Volume: 89, Issue:5

    Topics: Aging; Amino Acids; Amino Acids, Essential; Animals; Arginine; Asparagine; Cerebral Cortex; Culture Media; Glutamic Acid; Liver; Lysine; Organ Culture Techniques; Rats; Rats, Wistar; Spleen

2003
Arginase reciprocally regulates nitric oxide synthase activity and contributes to endothelial dysfunction in aging blood vessels.
    Circulation, 2003, Oct-21, Volume: 108, Issue:16

    Topics: Aging; Animals; Arginase; Arginine; Blood Vessels; Cyclic GMP; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Techniques; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents

2003
Strain differences to effects of aging on concentrations of amino acids in cerebrospinal fluid between Sprague Dawley rat and Wistar Kyoto rat.
    Experimental animals, 2003, Volume: 52, Issue:5

    Topics: Aging; Amino Acids; Animals; Arginine; Body Weight; Male; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Threonine

2003
Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging.
    The American journal of pathology, 2003, Volume: 163, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Arginine; Cell Death; Cryptorchidism; Cytoprotection; Gene Expression; Humans; Lysine; Male; Mice; Mice, Transgenic; Mutation; Spermatogenesis; Spermatozoa; Testis; Transgenes; Ubiquitin

2003
Nitric oxide and its influence on oscillations of collicular responses in developing rats.
    Journal of physiology, Paris, 2003, Volume: 97, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Arginine; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Evoked Potentials; Immunohistochemistry; Models, Neurological; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Periodicity; Rats; Rats, Long-Evans; Superior Colliculi

2003
Age-related changes of noncalcified collagen in human cortical bone.
    Annals of biomedical engineering, 2003, Volume: 31, Issue:11

    Topics: Adult; Aged; Aging; Arginine; Bone Remodeling; Cadaver; Collagen; Cross-Linking Reagents; Elasticity; Female; Femoral Fractures; Femur; Haversian System; Humans; Lysine; Male; Middle Aged; Osteogenesis; Osteoporosis; Protein Denaturation

2003
Age-dependent changes in the regulatory roles of nitric oxide and vasodilator prostanoids on the mechanical activities of isolated rabbit spinal arterioles.
    The Japanese journal of physiology, 2003, Volume: 53, Issue:5

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acetylcholine; Age Factors; Aging; Animals; Arginine; Arterioles; Cilostazol; Dose-Response Relationship, Drug; Epoprostenol; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Prostaglandins; Rabbits; Spinal Cord; Tetrazoles; Vasodilation; Vasodilator Agents

2003
Association between pentosidine and arteriosclerosis in patients receiving hemodialysis.
    Clinical and experimental nephrology, 2004, Volume: 8, Issue:1

    Topics: Aged; Aging; Aorta, Abdominal; Aortic Diseases; Arginine; Arteriosclerosis; Calcinosis; Female; Humans; Kidney Failure, Chronic; Lysine; Male; Middle Aged; Regression Analysis; Renal Dialysis; Time Factors; Tomography, X-Ray Computed

2004
Modulation of iNOS activity in age-related cardiac dysfunction.
    Life sciences, 2004, Jun-25, Volume: 75, Issue:6

    Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Antibody Technique, Indirect; Guanidines; Isothiuronium; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Ventricular Dysfunction, Left

2004
Perinatal L-arginine and antioxidant supplements reduce adult blood pressure in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 2004, Volume: 44, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Antioxidants; Arginine; Blood Pressure; Dietary Supplements; Female; Hypertension; Kidney; Male; Nitric Oxide; Oxidative Stress; Pregnancy; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive Oxygen Species

2004
Involvement of increased arginase activity in impaired cavernous relaxation with aging in the rabbit.
    The Journal of urology, 2004, Volume: 172, Issue:1

    Topics: Aging; Animals; Arginase; Arginine; Carbachol; Cholinergic Agonists; Endothelium, Vascular; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide Synthase; omega-N-Methylarginine; Penis; Rabbits

2004
Aging exacerbates negative remodeling and impairs endothelial regeneration after balloon injury.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:6

    Topics: Aging; Angioplasty, Balloon; Animals; Apoptosis; Arginine; Cell Cycle Proteins; Cell Division; Endothelium, Vascular; Hyperplasia; Muscle, Smooth, Vascular; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Regeneration

2004
Body mass index determines evoked growth hormone (GH) responsiveness in normal healthy male subjects: diagnostic caveat for adult GH deficiency.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:7

    Topics: Adult; Aging; Arginine; Body Mass Index; Case-Control Studies; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Obesity; Time Factors

2004
Do incremental increases in blood pressure elicit neointimal plaques through endothelial injury?
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 287, Issue:6

    Topics: Aging; Animals; Aorta, Abdominal; Arginine; Blood Pressure; Chickens; Disease Models, Animal; Endothelium, Vascular; Hemodynamics; Hypertension; Male; Propranolol; Solvents; Tunica Intima

2004
n-3 polyunsaturated fatty acids supplementation decreases asymmetric dimethyl arginine and arachidonate accumulation in aging spontaneously hypertensive rats.
    European journal of nutrition, 2005, Volume: 44, Issue:6

    Topics: Aging; Animals; Arachidonic Acid; Arginine; Cardiovascular Diseases; Dietary Supplements; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids, Omega-3; Male; Rats; Rats, Inbred SHR; Risk Factors

2005
Conversion of arginine into ornithine by advanced glycation in senescent human collagen and lens crystallins.
    The Journal of biological chemistry, 2004, Dec-24, Volume: 279, Issue:52

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Alkylation; Arginine; Borohydrides; Child; Chromatography, Liquid; Collagen; Crystallins; Formaldehyde; Furans; Glycation End Products, Advanced; Glycosylation; Humans; Hydrolysis; Lens, Crystalline; Middle Aged; Ornithine; Skin; Spectrometry, Mass, Electrospray Ionization

2004
The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Aging; Alleles; Arginine; Cell Line; Cysteine; DNA; DNA Helicases; DNA, Complementary; Escherichia coli; Exodeoxyribonucleases; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Humans; Hydrolysis; Immunoprecipitation; Models, Genetic; Models, Molecular; Mutation; Plasmids; Polymorphism, Genetic; Protein Structure, Tertiary; RecQ Helicases; Transfection; Werner Syndrome Helicase

2004
Effect of L-arginine on age-related changes in macrophage phagocytic activity.
    Immunological investigations, 2004, Volume: 33, Issue:3

    Topics: Aging; Animals; Arginine; Macrophages, Peritoneal; Male; Nitric Oxide; Phagocytosis; Rats; Rats, Wistar

2004
Changes in dolichol and pentosidine levels in the age-mismatched heterotopically transplanted rat heart.
    Biogerontology, 2004, Volume: 5, Issue:6

    Topics: Aging; Animals; Arginine; Biological Clocks; Connective Tissue; Dolichols; Heart Transplantation; Lysine; Male; Myocardium; Papillary Muscles; Rats; Rats, Inbred Lew; Transplantation, Heterotopic

2004
The influence of L-arginine on biomechanical parameters of native and nonenzymatically glycated rat tail tendons.
    Connective tissue research, 1994, Volume: 31, Issue:1

    Topics: Aging; Animals; Arginine; Calcium; Collagen; Dose-Response Relationship, Drug; Elasticity; Glucose; Glycation End Products, Advanced; Glycosylation; Male; Models, Biological; Molecular Structure; Protein Binding; Proteoglycans; Rats; Rats, Sprague-Dawley; Sodium; Tail; Tendons; Tensile Strength; Weight-Bearing

1994
Anatomically distinct activation of endothelin-3 and the L-arginine/nitric oxide pathway in the kidney with advanced aging.
    Biochemical and biophysical research communications, 2005, Feb-04, Volume: 327, Issue:1

    Topics: Aging; Animals; Arginine; Blood Pressure; Body Weight; Endothelin-3; Female; Gene Expression Regulation; Kidney; Nitric Oxide; Rats; Rats, Wistar; Receptors, Endothelin; Signal Transduction

2005
Kainate/estrogen receptor involvement in rapid estradiol effects in vitro and intracellular signaling pathways.
    Endocrinology, 2005, Volume: 146, Issue:5

    Topics: Aging; Animals; Arginine; Estradiol; Estrogen Receptor alpha; Female; Glutamic Acid; Gonadotropin-Releasing Hormone; Hypothalamus; Kinetics; Male; Median Eminence; Nitric Oxide; Preoptic Area; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, Glutamate; Receptors, Kainic Acid; Signal Transduction

2005
Cognitive deficits in aged rats correlate with levels of L-arginine, not with nNOS expression or 3,4-DAP-evoked transmitter release in the frontoparietal cortex.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2005, Volume: 15, Issue:2

    Topics: 4-Aminopyridine; Acetylcholine; Aging; Amifampridine; Animals; Arginine; Cerebral Cortex; Cognition Disorders; Female; Frontal Lobe; Gene Expression Regulation; Nerve Tissue Proteins; Neurotransmitter Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Norepinephrine; Parietal Lobe; Rats; Rats, Long-Evans; Serotonin

2005
GPR40 gene Arg211His polymorphism may contribute to the variation of insulin secretory capacity in Japanese men.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Adult; Aged; Aging; Arginine; Body Mass Index; Genotype; Histidine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Japan; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Receptors, G-Protein-Coupled; Regression Analysis

2005
Effects of intrauterine food restriction and long-term dietary supplementation with L-arginine on age-related changes in renal function and structure of rats.
    Pediatric research, 2005, Volume: 57, Issue:5 Pt 1

    Topics: Actins; Aging; Animals; Arginine; Blood Pressure; Dietary Supplements; Female; Fetal Growth Retardation; Fibronectins; Food Deprivation; Glomerular Filtration Rate; Glomerulonephritis; Immunohistochemistry; Kidney; Placental Insufficiency; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Proteinuria; Rats; Rats, Wistar; Time Factors; Weight Gain

2005
Renovascular effects of sympathetic cotransmitters ATP and NPY are age-dependent in spontaneously hypertensive rats.
    Cardiovascular research, 2005, May-01, Volume: 66, Issue:2

    Topics: Adenosine Triphosphate; Aging; Animals; Arginine; Dose-Response Relationship, Drug; Electric Stimulation; Kidney; Male; Neuropeptide Y; Norepinephrine; Perfusion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Neuropeptide Y; Receptors, Purinergic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sympathetic Nervous System

2005
Functional characterization of brain mitochondrial nitric oxide synthase during hypertension and aging.
    Amino acids, 2006, Volume: 30, Issue:1

    Topics: Aging; Animals; Arginine; Brain; Citrulline; Hypertension; Indazoles; Male; Mitochondria; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar

2006
Effects of energy restriction and fish oil supplementation on renal guanidino levels and antioxidant defences in aged lupus-prone B/W mice.
    The British journal of nutrition, 2005, Volume: 93, Issue:6

    Topics: Acetic Acid; Aging; Animals; Antioxidants; Arginine; Catalase; Creatinine; Dietary Supplements; Energy Intake; Female; Fish Oils; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Guanidine; Kidney; Lupus Vulgaris; Mice; Mice, Inbred Strains; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase

2005
Immunohistochemical localization of advanced glycation end products in pinguecula.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2006, Volume: 244, Issue:1

    Topics: Adult; Aged; Aging; Antibodies, Monoclonal; Arginine; Conjunctival Diseases; Female; Glycation End Products, Advanced; Humans; Imidazoles; Immunoenzyme Techniques; Lysine; Male; Middle Aged; Norleucine; Pyrroles

2006
Ornithine is a novel amino acid and a marker of arginine damage by oxoaldehydes in senescent proteins.
    Annals of the New York Academy of Sciences, 2005, Volume: 1043

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Child; Collagen; Glycation End Products, Advanced; Humans; Middle Aged; Ornithine; Skin Aging

2005
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
    Cell cycle (Georgetown, Tex.), 2005, Volume: 4, Issue:9

    Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; beta-Galactosidase; Bromodeoxyuridine; Cell Cycle; Cell Death; Cell Separation; Cells, Cultured; Chromatin Immunoprecipitation; Codon; Cyclin-Dependent Kinase Inhibitor p21; Fibroblasts; Flow Cytometry; Homozygote; Humans; Luciferases; Microscopy, Fluorescence; Neoplasms; Oligonucleotides; Oxidative Stress; Polymorphism, Genetic; Proline; Propidium; Protein Isoforms; Transfection

2005
eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:2

    Topics: Aging; Animals; Arginine; Biopterins; Calcimycin; Endothelium, Vascular; Enzyme Activation; Fetus; HSP90 Heat-Shock Proteins; Humans; Nitric Oxide Synthase Type III; Pulmonary Artery; Reactive Oxygen Species; Recombinant Proteins; Sheep; Stress, Mechanical; Superoxides; Vascular Endothelial Growth Factor A; Vasodilation

2006
A reversal by L-arginine and sodium nitroprusside of ageing-induced memory impairment in rats by increasing nitric oxide concentration in the hippocampus.
    Indian journal of physiology and pharmacology, 2005, Volume: 49, Issue:2

    Topics: Aging; Animals; Arginine; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Hippocampus; Male; Memory Disorders; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar; Reaction Time; Rotation; Time Factors

2005
Determination of a reference value for N(G), N(G)-dimethyl-L-arginine in 500 subjects.
    European journal of clinical investigation, 2005, Volume: 35, Issue:10

    Topics: Adult; Aged; Aging; Arginine; Biomarkers; Cardiovascular Diseases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Nitric Oxide Synthase; Reference Values; Sensitivity and Specificity; Sex Characteristics

2005
Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover.
    Diabetologia, 2006, Volume: 49, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Blood Glucose; Body Composition; Female; Glucose; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Middle Aged; Obesity; omega-N-Methylarginine; Proteins; Regression Analysis; Sex Characteristics

2006
Knockdown of arginase I restores NO signaling in the vasculature of old rats.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:2

    Topics: Acetylcholine; Aging; Animals; Aorta; Arginase; Arginine; Calcium; Drug Synergism; Enzyme Inhibitors; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Oligonucleotides, Antisense; Oxadiazoles; Phenylephrine; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Up-Regulation; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2006
L-Arginine supplementation or arginase inhibition augments reflex cutaneous vasodilatation in aged human skin.
    The Journal of physiology, 2006, Jul-15, Volume: 574, Issue:Pt 2

    Topics: Adolescent; Adult; Aged; Aging; Arginase; Arginine; Biological Availability; Female; Humans; Male; Nitric Oxide; Nitric Oxide Synthase; Skin; Up-Regulation; Vasodilation

2006
Age-related effects on the biological clock and its behavioral output in a primate.
    Chronobiology international, 2006, Volume: 23, Issue:1-2

    Topics: Aging; Animals; Arginine; Behavior, Animal; Biological Clocks; Cheirogaleidae; Circadian Rhythm; Neuropeptides; Peptides; Primates; Suprachiasmatic Nucleus; Time Factors; Vasoactive Intestinal Peptide; Vasopressins

2006
Effect of L-arginine on asymmetric dimethylarginine (ADMA) or homocysteine-accelerated endothelial cell aging.
    Biochemical and biophysical research communications, 2006, Jul-07, Volume: 345, Issue:3

    Topics: Aging; Arginine; Cells, Cultured; Cellular Senescence; Endothelial Cells; Endothelium, Vascular; Homocysteine; Humans; NG-Nitroarginine Methyl Ester; Oxidative Stress; Telomerase; Time Factors

2006
L-arginine supplementation causes additional effects on exercise-induced angiogenesis and VEGF expression in the heart and hind-leg muscles of middle-aged rats.
    The journal of physiological sciences : JPS, 2006, Volume: 56, Issue:1

    Topics: Aging; Animals; Arginine; Blotting, Western; Capillaries; Coronary Vessels; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation, Enzymologic; Heart Ventricles; Hindlimb; Histocytochemistry; Male; Muscle, Skeletal; Myocardium; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Physical Conditioning, Animal; Rats; Rats, Wistar; Vascular Endothelial Growth Factor A

2006
Age-related accumulation of pentosidine in aggrecan and collagen from normal and degenerate human intervertebral discs.
    The Biochemical journal, 2006, Oct-01, Volume: 399, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Chondroitin Sulfate Proteoglycans; Collagen; Discitis; Extracellular Matrix Proteins; Humans; Intervertebral Disc; Lectins, C-Type; Lysine; Middle Aged; Proteoglycans

2006
The cardiovascular risk marker asymmetrical dimethylarginine is not affected by venous thromboembolism.
    Translational research : the journal of laboratory and clinical medicine, 2006, Volume: 148, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Body Mass Index; Female; Fibrin Fibrinogen Degradation Products; Humans; Male; Middle Aged; Risk Factors; Venous Thrombosis

2006
Impaired flow-mediated dilation with age is not explained by L-arginine bioavailability or endothelial asymmetric dimethylarginine protein expression.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 102, Issue:1

    Topics: Adolescent; Adult; Aged; Aging; Amidohydrolases; Arginine; Biological Availability; Brachial Artery; Carotid Arteries; Endothelium, Vascular; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Regional Blood Flow; Vasodilation

2007
The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo.
    Human molecular genetics, 2007, Apr-15, Volume: 16, Issue:8

    Topics: Aging; Animals; Arginine; CADASIL; Cerebral Arteries; Cysteine; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Intracranial Arterial Diseases; Lac Operon; Mice; Mice, Knockout; Mutant Proteins; Mutation, Missense; Protein Structure, Tertiary; Receptor, Notch3; Receptors, Notch; Transgenes

2007
Disruption of NO-cGMP signaling by neonatal hyperoxia impairs relaxation of lung parenchyma.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Arginase; Arginine; Cyclic GMP; Electric Stimulation; Enzyme Inhibitors; Hyperoxia; In Vitro Techniques; Lung; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Signal Transduction

2007
Collagen, cross-linking, and advanced glycation end products in aging human skeletal muscle.
    Journal of applied physiology (Bethesda, Md. : 1985), 2007, Volume: 103, Issue:6

    Topics: Actins; Activities of Daily Living; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Collagen; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Muscle Contraction; Muscle Strength; Muscular Diseases; Myofibrils; Myosins; Quadriceps Muscle

2007
[Effect of seleno-arginine on cellular immunological function in D-gal aging mice].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2007, Volume: 23, Issue:12

    Topics: Aging; Animals; Arginine; CD40 Antigens; Cell Proliferation; Dietary Supplements; Female; Fluorescent Antibody Technique; Galactose; Gene Expression Regulation; Killer Cells, Natural; Male; Mice; Selenium; Spleen; Thymus Gland

2007
Ageing diminishes endothelium-dependent vasodilatation and tetrahydrobiopterin content in rat skeletal muscle arterioles.
    The Journal of physiology, 2008, Feb-15, Volume: 586, Issue:4

    Topics: Aging; Animals; Arginase; Arginine; Arterioles; Biopterins; Endothelium, Vascular; Enzyme Inhibitors; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Pterins; Rats; Rats, Inbred F344; Vasodilation

2008
Contents of pentosidine in the tissue of the intervertebral disc as an indicator of the human age.
    Soudni lekarstvi, 2007, Volume: 52, Issue:4

    Topics: Adolescent; Adult; Age Determination by Skeleton; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Glycation End Products, Advanced; Humans; Intervertebral Disc; Lumbar Vertebrae; Lysine; Middle Aged

2007
iNOS activity in the aged rat liver tissue.
    Journal of biological regulators and homeostatic agents, 2007, Volume: 21, Issue:3-4

    Topics: Aging; Animals; Arginine; Blotting, Western; Citrulline; Gene Expression; Immunohistochemistry; Kidney; Liver; Male; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction

2007
Effect of beta-blockers on endothelial function during biological aging: a nanotechnological approach.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:2

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Aorta, Thoracic; Arginine; Atenolol; Cellular Senescence; Endothelium, Vascular; In Vitro Techniques; Metoprolol; Nanotechnology; Nitric Oxide; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Pterins; Rats; Rats, Inbred WKY; Superoxide Dismutase

2008
Effect of amino acid supplementation on muscle mass, strength and physical function in elderly.
    Clinical nutrition (Edinburgh, Scotland), 2008, Volume: 27, Issue:2

    Topics: Absorptiometry, Photon; Aged; Aging; Amino Acids, Essential; Arginine; Body Composition; Dietary Supplements; Female; Gait; Glucose Intolerance; Humans; Lower Extremity; Male; Muscle Strength; Muscle Strength Dynamometer; Muscle, Skeletal; Treatment Outcome

2008
Potential ergogenic effects of L-arginine against oxidative and inflammatory stress induced by acute exercise in aging rats.
    Experimental gerontology, 2008, Volume: 43, Issue:6

    Topics: Aging; Animals; Arginine; Biomarkers; Dietary Supplements; Inflammation; Kidney; Lactic Acid; Liver; Lung; Male; Muscle, Skeletal; Myocardium; Oxidation-Reduction; Peroxidase; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Xanthine Oxidase

2008
[Protein synthesis and the regulation process in the cell].
    Arkhiv anatomii, gistologii i embriologii, 1966, Volume: 50, Issue:5

    Topics: Aging; Animals; Arginine; Autoradiography; Axons; Body Weight; Cell Biology; Cytoplasmic Granules; Glycine; Golgi Apparatus; Guinea Pigs; Hippocampus; Homeostasis; Leucine; Methionine; Mice; Microscopy, Electron; Neurons; Pancreas; Photoreceptor Cells; Protein Biosynthesis; Purkinje Cells; Pyramidal Tracts; Rats; Ribosomes; RNA; RNA, Messenger; Spectrophotometry; Thyroid Gland; Time Factors; Tritium; Tyrosine

1966
Insulin, glucagon, and somatostatin release from the prediabetic Chinese hamster.
    Diabetologia, 1984, Volume: 27, Issue:3

    Topics: Aging; Animals; Arginine; Cricetinae; Cricetulus; Diabetes Mellitus, Experimental; Glucagon; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mutation; Prediabetic State; Somatostatin

1984
Differential effects of microtubule-altering agents on beta-cells during development.
    The American journal of physiology, 1983, Volume: 245, Issue:4

    Topics: Aging; Animals; Arginine; Deuterium; Deuterium Oxide; Female; Fetus; Gestational Age; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Microtubules; Pregnancy; Rats; Rats, Inbred Strains; Vinblastine; Water

1983
Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:4

    Topics: Adult; Aging; Arginine; Blood Glucose; Catecholamines; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucagon; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Obesity

1984
Improvement of nitrogen retention by arginine and glycine supplementation and its relation to collagen synthesis in traumatized mature and aged rats.
    The Journal of nutrition, 1984, Volume: 114, Issue:9

    Topics: Aging; Animals; Arginine; Collagen; Food, Fortified; Glycine; Hydroxyproline; Male; Nitrogen; Rats; Rats, Inbred F344; Wound Healing; Wounds and Injuries

1984
Urinary excretion of dimethylarginines in premature infants.
    Biochemical medicine, 1984, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Aging; Arginine; Body Weight; Child; Child, Preschool; Diet; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Methylhistidines; Muscle Proteins; Nitrogen; Proteins

1984
Higher excretion of urinary bound amino acids in infants: probably related to protein-anabolic effect of growth hormone.
    The Tohoku journal of experimental medicine, 1982, Volume: 137, Issue:1

    Topics: Aging; Alanine; Amino Acids; Arginine; Child; Child, Preschool; Cystine; Cystinuria; Glycine; Growth Hormone; Histidine; Humans; Infant; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proteins; Valine

1982
Serum glucagon after arginine infusion in aged and young subjects.
    Journal of the American Geriatrics Society, 1980, Volume: 28, Issue:6

    Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Diabetes Mellitus; Glucagon; Growth Hormone; Humans; Infusions, Parenteral; Insulin

1980
Hormonal control of glucose homeostasis during development and ageing in mice.
    Metabolism: clinical and experimental, 1982, Volume: 31, Issue:3

    Topics: Aging; Animals; Arginine; Blood Glucose; Catecholamines; Cortisone; Glucagon; Growth Hormone; Homeostasis; Hormones; Insulin; Mice; Mice, Obese

1982
Developmental modulations of blood-brain barrier permeability as an indicator of changing nutritional requirements in the brain.
    Pediatric research, 1982, Volume: 16, Issue:4 Pt 1

    Topics: Adenine; Aging; Animals; Animals, Newborn; Arginine; Blood-Brain Barrier; Brain; Butanols; Choline; Glucose; Lactates; Permeability; Rabbits; Tryptophan

1982
Effect of dietary arginine level on urinary orotate and citrate excretion in growing kittens.
    The Journal of nutrition, 1980, Volume: 110, Issue:6

    Topics: Aging; Animals; Arginine; Cats; Citrates; Diet; Dose-Response Relationship, Drug; Female; Male; Nutritional Requirements; Orotic Acid

1980
Arginyl-tRNA transferase activity as a marker of cellular aging in peripheral rat tissues.
    Experimental gerontology, 1980, Volume: 15, Issue:1

    Topics: Acyltransferases; Aging; Aminoacyltransferases; Animals; Arginine; Brain; Chromatin; Chromosomal Proteins, Non-Histone; Kidney; Liver; Male; Rats; RNA, Transfer; Tissue Distribution

1980
Developmental changes of free amino acid concentrations in fetal fluids of pigs.
    The Journal of nutrition, 1995, Volume: 125, Issue:11

    Topics: Aging; Allantois; Amino Acids; Ammonia; Amniotic Fluid; Animals; Arginine; Female; Fetal Blood; Gestational Age; Glutamine; Glycine; Male; Ornithine; Placenta; Pregnancy; Swine; Urea; Uterus

1995
Nitric oxide and beta-adrenergic mechanisms modify contractile responses to norepinephrine in ovine fetal and newborn cerebral arteries.
    Pediatric research, 1995, Volume: 38, Issue:2

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Animals, Newborn; Arginine; Cerebral Arteries; Embryonic and Fetal Development; Enzyme Inhibitors; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Propranolol; Receptors, Adrenergic, beta; Sheep; Vasoconstrictor Agents; Vasodilator Agents

1995
The role of hyperthermia in amphetamine's interactions with NMDA receptors, nitric oxide, and age to produce neurotoxicity.
    Annals of the New York Academy of Sciences, 1995, Sep-15, Volume: 765

    Topics: Aging; Amphetamine; Animals; Arginine; Brain; Dizocilpine Maleate; Fever; Glutamic Acid; Haloperidol; Methamphetamine; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism

1995
The NSY mouse: a new animal model of spontaneous NIDDM with moderate obesity.
    Diabetologia, 1995, Volume: 38, Issue:5

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Intolerance; Humans; Hypertrophy; Inflammation; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Mice, Mutant Strains; Obesity; Sex Characteristics; Time Factors

1995
Age-dependent decrease in endothelium-dependent hyperpolarizations to endothelin-3 in the rat mesenteric artery.
    Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 8

    Topics: Acetylcholine; Aging; Animals; Arginine; Endothelins; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Nitroarginine; Rats; Rats, Inbred WKY

1993
Effect of ageing on tissue levels of amino acids involved in the nitric oxide pathway in rat brain.
    Journal of neural transmission. General section, 1993, Volume: 94, Issue:1

    Topics: Aging; Amino Acid Oxidoreductases; Amino Acids; Animals; Arginine; Aspartic Acid; Brain Chemistry; Citrulline; Glutamates; Glutamic Acid; Male; Nitric Oxide; Nitric Oxide Synthase; Ornithine; Rats; Rats, Wistar

1993
Different pial arteriolar responses to acetylcholine in the newborn and juvenile pig.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1994, Volume: 14, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Arterioles; Calcimycin; Cerebrovascular Circulation; Cyclic GMP; Female; Male; Nitroarginine; Nitroprusside; Pia Mater; Swine

1994
Abolition of flow-dependent EDRF release before that evoked by agonists in hypercholesterolaemic rabbits.
    British journal of pharmacology, 1994, Volume: 113, Issue:1

    Topics: Acetylcholine; Aging; Animals; Arginine; Blood Viscosity; Cholesterol; Cholesterol, Dietary; Dextrans; Hypercholesterolemia; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits

1994
Effect of aging on nitric oxide-mediated penile erection in rats.
    The American journal of physiology, 1995, Volume: 268, Issue:1 Pt 2

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Dose-Response Relationship, Drug; Egtazic Acid; Electric Stimulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroglycerin; Papaverine; Penile Erection; Penis; Rats; Rats, Inbred F344

1995
Nitric oxide synthesis and the effect of aminoguanidine and NG-monomethyl-L-arginine on the onset of diabetes in the spontaneously diabetic BB rat.
    Diabetes, 1995, Volume: 44, Issue:3

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Diabetes Mellitus, Type 1; Guanidines; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Rats; Rats, Inbred BB; Species Specificity; Time Factors

1995
N omega-nitro-L-arginine methyl ester reduces the incidence of IDDM in BB/E rats.
    Diabetes, 1995, Volume: 44, Issue:3

    Topics: Administration, Oral; Aging; Amino Acid Oxidoreductases; Animals; Arginine; Blood Glucose; Blood Pressure; Body Weight; Diabetes Mellitus, Type 1; Female; Insulin; Intestines; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Inbred BB

1995
Impairment of the priming effect of glucose on insulin secretion from isolated islets of aging rats.
    Acta diabetologica, 1995, Volume: 32, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Blood Glucose; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Kinetics; Male; Rats; Rats, Sprague-Dawley

1995
Endothelial nucleotide-mediated aorta relaxation in aged Watanabe heritable hyperlipidemic rabbits.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1

    Topics: Acetylcholine; Adenosine Triphosphate; Aging; Animals; Aorta, Thoracic; Arginine; Arteriosclerosis; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Hyperlipidemia, Familial Combined; Male; Methylene Blue; Microscopy, Electron; Microscopy, Electron, Scanning; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Purinergic Antagonists; Rabbits; Receptors, Muscarinic; Receptors, Purinergic; Suramin; Uridine Triphosphate

1995
Effect of aging and hypertension on contractility of resistance arteries: modulation by endothelial factors.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Aging; Angiotensins; Animals; Arginine; Arteries; Blood Pressure; Body Weight; Endothelium, Vascular; Hypertension; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Norepinephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents

1995
Arginine synthesis in enterocytes of neonatal pigs.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Aging; Animals; Animals, Newborn; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Body Fluids; Citrulline; DNA; Glutamine; Jejunum; Kidney; Ornithine; Osmolar Concentration; Proline; Swine

1995
Caloric restriction decreases age-dependent accumulation of the glycoxidation products, N epsilon-(carboxymethyl)lysine and pentosidine, in rat skin collagen.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50, Issue:6

    Topics: Aging; Animals; Arginine; Blood Proteins; Chromatography, High Pressure Liquid; Collagen; Energy Intake; Female; Food Deprivation; Glycation End Products, Advanced; Lysine; Oxidation-Reduction; Rats; Rats, Inbred BN; Skin

1995
Roles of nitric oxide and endothelium-derived hyperpolarizing factor in vasorelaxant effect of acetylcholine as influenced by aging and hypertension.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:4

    Topics: Acetylcholine; Aging; Animals; Arginine; Biological Factors; Blood Pressure; Hypertension; In Vitro Techniques; Muscle Tonus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Splanchnic Circulation; Tetraethylammonium Compounds; Vasodilation

1995
An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Jun-20, Volume: 92, Issue:13

    Topics: Aging; Alanine; Alleles; Animals; Apoptosis; Arginine; Cell Differentiation; Codon; Epithelial Cells; Gene Expression; Genes, p53; Genetic Therapy; Humans; Lens, Crystalline; Mice; Mice, Transgenic; Microphthalmos; Point Mutation; Proline; Tumor Suppressor Protein p53; Valine

1995
Role of nitric oxide in regulation of vascular resistance in postnatal intestine.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 1

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Arginine; Blood Pressure; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Infusions, Intra-Arterial; Intestines; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Oxygen; Partial Pressure; Potassium Chloride; Regional Blood Flow; Swine; Vascular Resistance

1995
Evidence for the Maillard reaction in rat lung collagen and its relationship with solubility and age.
    Biochimica et biophysica acta, 1995, Aug-15, Volume: 1272, Issue:1

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Extracellular Matrix; Hydroxyproline; Lung; Lysine; Maillard Reaction; Rats; Rats, Sprague-Dawley; Solubility; Spectrometry, Fluorescence

1995
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-01, Volume: 90, Issue:1

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Animals, Newborn; Arginine; Carbachol; Cells, Cultured; Cyclic GMP; Heart; Heart Rate; Heart Ventricles; Isoproterenol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Oxyhemoglobins; Rats; Signal Transduction

1993
The suppression of long-term potentiation in rat hippocampus by inhibitors of nitric oxide synthase is temperature and age dependent.
    Neuron, 1993, Volume: 11, Issue:5

    Topics: Aging; Amino Acid Oxidoreductases; Animals; Arginine; Hemoglobins; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Temperature

1993
Vasomotor reactivity and catecholamine, arginine vasopressin plasma levels during ageing and development in rats.
    Mechanisms of ageing and development, 1994, Nov-25, Volume: 77, Issue:1

    Topics: Acetylcholine; Aging; Animals; Arginine; Arterial Occlusive Diseases; Blood Pressure; Carotid Artery Diseases; Catecholamines; Hyperlipidemias; Hypertension; Isoproterenol; Norepinephrine; Rats; Rats, Inbred Strains; Vasomotor System; Vasopressins

1994
Age-related changes in vascular reactivity in genetically diabetic rats.
    Pharmacology, 1995, Volume: 50, Issue:4

    Topics: Acetylcholine; Aging; Animals; Arginine; Calcimycin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Zucker

1995
The role of islet secretory function in the development of diabetes in the GK Wistar rat.
    Diabetologia, 1994, Volume: 37, Issue:9

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Glyceraldehyde; Glycerol; In Vitro Techniques; Islets of Langerhans; Kinetics; Male; Potassium Chloride; Rats; Rats, Wistar; Reference Values

1994
Developmental effects of endothelin-1 on the pulmonary circulation in sheep.
    Pediatric research, 1994, Volume: 36, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Arginine; Endothelins; Glyburide; Hemodynamics; Hypertension, Pulmonary; Meclofenamic Acid; Nitric Oxide; Nitroarginine; Potassium Channel Blockers; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Pulmonary Circulation; Sheep; Thromboxane A2; Vasoconstrictor Agents

1994
Effects of aging and caloric restriction on extracellular matrix biosynthesis in a model of injury repair in rats.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1995, Volume: 50A, Issue:1

    Topics: Aging; Animals; Arginine; Collagen; Cross-Linking Reagents; Dipeptides; Energy Intake; Granulation Tissue; Lysine; Male; Rats; Rats, Inbred F344; Time Factors; Wound Healing

1995
Effect of 15-day treatment with growth-hormone-releasing hormone alone or combined with different doses of arginine on the reduced somatotrope responsiveness to the neurohormone in normal aging.
    European journal of endocrinology, 1995, Volume: 132, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Aging; Arginine; Dose-Response Relationship, Drug; Drug Combinations; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Injections, Intravenous; Male; Reference Values; Time Factors

1995
Lysyl oxidase and Maillard reaction-mediated crosslinks in aging and osteoarthritic rabbit cartilage.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1995, Volume: 13, Issue:1

    Topics: Aging; Amino Acids; Animals; Arginine; Cartilage, Articular; Collagen; Female; Lysine; Maillard Reaction; Osteoarthritis; Peptide Mapping; Protein-Lysine 6-Oxidase; Rabbits; Solubility

1995
Glutamine and glucose metabolism in enterocytes of the neonatal pig.
    The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 2

    Topics: Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Arginine; Citrulline; Glucose; Glutamine; Jejunum; Oxygen Consumption; Swine

1995
The possible role and treatment of deficient microcirculation regulation in age-associated memory impairment.
    Medical hypotheses, 1994, Volume: 42, Issue:6

    Topics: Acetylcholine; Aging; Animals; Arginine; Arterioles; Brain; Cerebrovascular Circulation; Drug Tolerance; Endothelium, Vascular; Humans; Hypertension; Memory Disorders; Microcirculation; Models, Biological; Nitric Oxide; Vasodilator Agents

1994
Changes in nitric oxide precursor, L-arginine, and metabolites, nitrate and nitrite, with aging.
    Life sciences, 1994, Volume: 55, Issue:24

    Topics: Aging; Animals; Arginine; Fasting; Glomerular Filtration Rate; Male; Nitrates; Nitric Oxide; Nitrites; Proteinuria; Rats; Rats, Sprague-Dawley

1994
Blunted growth hormone response to intravenous arginine in subjects with a spinal cord injury.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1994, Volume: 26, Issue:3

    Topics: Adult; Aging; Arginine; Body Mass Index; Glucose Tolerance Test; Growth Hormone; Humans; Insulin-Like Growth Factor I; Kinetics; Middle Aged; Spinal Cord Injuries

1994
L-arginine-nitric oxide pathway and chronic nephropathy in aged rats.
    Journal of gerontology, 1994, Volume: 49, Issue:4

    Topics: Aging; Amino Acids; Animals; Arginine; Blood Urea Nitrogen; Chronic Disease; Creatinine; Dietary Proteins; Dilatation, Pathologic; Guanidines; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Inbred F344; Sclerosis; Specific Pathogen-Free Organisms

1994
Effect of large doses of the nitric oxide precursor, L-arginine, on erectile dysfunction.
    International journal of impotence research, 1994, Volume: 6, Issue:1

    Topics: Adult; Aged; Aging; Arginine; Erectile Dysfunction; Humans; Male; Middle Aged; Nitric Oxide; Penis; Pilot Projects; Regional Blood Flow

1994
Hypertension and ageing impair acetylcholine-induced vasodilation in rats.
    Journal of hypertension, 1994, Volume: 12, Issue:3

    Topics: Acetylcholine; Aging; Animals; Arginine; Blood Pressure; Hemodynamics; Hypertension; Male; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasodilation

1994
Altered renal vascular responses in the aging rat kidney.
    The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 2

    Topics: Aging; Angiotensin II; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Endothelins; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Renal Circulation; Tetrazoles

1994
Nitric oxide production and neurotoxicity mediated by activated microglia from human versus mouse brain.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:2

    Topics: Aged; Aging; Animals; Animals, Newborn; Arginine; Brain; Cells, Cultured; gamma-Aminobutyric Acid; Humans; Interferon-gamma; L-Lactate Dehydrogenase; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Microglia; Middle Aged; Neurons; Nitric Oxide; omega-N-Methylarginine; Recombinant Proteins; Tumor Necrosis Factor-alpha

1994
Norepinephrine-induced relaxations in rat aorta mediated by endothelial beta adrenoceptors. Impairment by ageing and hypertension.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2

    Topics: Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Hypertension; In Vitro Techniques; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Norepinephrine; Ouabain; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Adrenergic, beta; Yohimbine

1994
Functional versus structural changes in the pathophysiology of acute ischemic renal failure in aging rats.
    Kidney international, 1994, Volume: 45, Issue:5

    Topics: Acute Kidney Injury; Aging; Animals; Arginine; Dietary Proteins; Glomerular Filtration Rate; Ischemia; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thiourea

1994
Glutamate and theta-rhythm stimulation selectively enhance NMDA component of EPSC in CA1 neurons of young rats.
    Neuroscience letters, 1993, Mar-05, Volume: 151, Issue:1

    Topics: Aging; Animals; Arginine; Evoked Potentials; Glutamates; Glutamic Acid; Hemoglobins; In Vitro Techniques; N-Methylaspartate; Neuronal Plasticity; Neurons; Nitroarginine; Norepinephrine; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Theta Rhythm

1993
Influence of age and long-term dietary restriction on enzymatically mediated crosslinks and nonenzymatic glycation of collagen in mice.
    Journal of gerontology, 1994, Volume: 49, Issue:2

    Topics: Aging; Animals; Aorta; Arginine; Collagen; Cross-Linking Reagents; Food Deprivation; Glycosylation; Lung; Lysine; Male; Mice; Mice, Inbred C57BL; Skin; Spectrometry, Fluorescence; Tendons

1994
L-arginine reduces kidney collagen accumulation and N-epsilon-(carboxymethyl)lysine in the aging NMRI-mouse.
    Journal of gerontology, 1994, Volume: 49, Issue:2

    Topics: Aging; Animals; Arginine; Basement Membrane; Collagen; Electrophoresis, Polyacrylamide Gel; Female; Glycosylation; Hydroxyproline; Kidney; Kidney Glomerulus; Lysine; Mice

1994
Quantitative analysis of crosslinks pyridinoline and pentosidine in articular cartilage of patients with bone and joint disorders.
    Arthritis and rheumatism, 1994, Volume: 37, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Bone Diseases; Cartilage, Articular; Chromatography, High Pressure Liquid; Chronic Kidney Disease-Mineral and Bone Disorder; Cross-Linking Reagents; Female; Femur Head Necrosis; Hip Joint; Humans; Joint Diseases; Knee Joint; Lysine; Male; Middle Aged; Osteoarthritis; Osteoporosis

1994
Pulmonary endothelial nitric oxide production is developmentally regulated in the fetus and newborn.
    The American journal of physiology, 1993, Volume: 265, Issue:4 Pt 2

    Topics: Aging; Animals; Animals, Newborn; Arginine; Cyclic GMP; Embryonic and Fetal Development; Endothelium, Vascular; Fetus; In Vitro Techniques; Nitric Oxide; Oxygen; Pulmonary Artery; Sheep

1993
Role of endothelium-derived nitric oxide in control of renal microvasculature in aging male rats.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2

    Topics: Aging; Animals; Arginine; Arterioles; Blood Pressure; Glomerular Filtration Rate; Hematocrit; Kidney Glomerulus; Male; Microcirculation; Nitric Oxide; Nitroarginine; Rats; Rats, Sprague-Dawley; Reference Values; Regional Blood Flow; Renal Circulation; Vascular Resistance

1993
Differential effects of type 2 (non-insulin-dependent) diabetes mellitus on pentosidine formation in skin and glomerular basement membrane.
    Diabetologia, 1993, Volume: 36, Issue:10

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Basement Membrane; Biomarkers; Child; Cross-Linking Reagents; Diabetes Mellitus, Type 2; Female; Humans; Infant; Kidney Glomerulus; Lysine; Male; Middle Aged; Skin; Skin Aging

1993
Effects of repeated stress on plasma arginine levels in young and old rats.
    Physiology & behavior, 1993, Volume: 54, Issue:4

    Topics: Adaptation, Psychological; Aging; Animals; Arginine; Immobilization; Male; Rats; Rats, Inbred F344; Stress, Psychological

1993
Spontaneous glucose intolerance in the progeny of low dose streptozotocin-induced diabetic mice.
    Diabetologia, 1993, Volume: 36, Issue:12

    Topics: Aging; Animals; Arginine; Body Weight; Diabetes Mellitus, Experimental; Female; Glucose; Glucose Intolerance; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Pancreatic Diseases; Pregnancy; Pregnancy in Diabetics; Sex Factors; Species Specificity

1993
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:8

    Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine

1993
Modulation by aging of the coronary vascular response to endothelin-1 in the rat isolated perfused heart.
    Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:1

    Topics: Acetylcholine; Aging; Animals; Arginine; Coronary Circulation; Coronary Vessels; Endothelins; Hemoglobins; In Vitro Techniques; Male; Nitric Oxide; Nitroarginine; Nitroprusside; Perfusion; Prostaglandins; Rats; Rats, Inbred F344

1993
Developmental and biochemical characteristics of the cardiac membrane-bound arginine-specific mono-ADP-ribosyltransferase.
    The Biochemical journal, 1993, Aug-01, Volume: 293 ( Pt 3)

    Topics: ADP Ribose Transferases; Aging; Animals; Arginine; Bacillus cereus; Cell Membrane; Glycosylphosphatidylinositols; Heart; Myocardium; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Species Specificity

1993
Quantification of the cross-link pentosidine in serum from normal and uremic subjects.
    Clinical chemistry, 1993, Volume: 39, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Diabetes Complications; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Uremia

1993
Decreased arteriolar endothelium-derived relaxing factor production during the development of genetic hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1993, Volume: 15, Issue:3

    Topics: Acetylcholine; Aging; Animals; Arginine; Arterioles; Hypertension; Male; Microcirculation; Muscles; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stimulation, Chemical

1993
Hypersecretion of amylin from the perfused pancreas of genetically obese (fa/fa) rats and its alteration with aging.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:5

    Topics: Aging; Amyloid; Animals; Arginine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islet Amyloid Polypeptide; Male; Obesity; Pancreas; Perfusion; Rats; Rats, Zucker; Reference Values

1993
Angiotensin II-induced endothelium-dependent relaxation of fowl aorta.
    The American journal of physiology, 1993, Volume: 264, Issue:5 Pt 2

    Topics: Acetylcholine; Aging; Angiotensin II; Animals; Aorta; Arginine; Calcium; Endothelium, Vascular; Female; Gossypol; Hydroquinones; NG-Nitroarginine Methyl Ester; Poultry; Vasoconstrictor Agents; Vasodilation

1993
GLUT2 expression and function in beta-cells of GK rats with NIDDM. Dissociation between reductions in glucose transport and glucose-stimulated insulin secretion.
    Diabetes, 1993, Volume: 42, Issue:7

    Topics: Aging; Animals; Arginine; Biological Transport; Cell Membrane; Diabetes Mellitus, Type 2; Gene Expression; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Monosaccharide Transport Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; RNA, Messenger; Species Specificity

1993
Accumulation of Maillard reaction products in skin collagen in diabetes and aging.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Diabetes Mellitus, Type 1; Female; Glycosylation; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Oxidation-Reduction; Skin; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1993
Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jan-09, Volume: 93, Issue:1

    Topics: Aging; Animals; Arginine; Cattle; Collagen; Cross-Linking Reagents; Diet; Dogs; Glucose; Humans; Longevity; Lysine; Macaca mulatta; Oxidation-Reduction; Rats; Regression Analysis; Saimiri; Skin; Swine

1996
Secretion of insulin and glucagon by the perfused pancreas of genetically obese (fa/fa) Zucker rats and its alteration with aging.
    Endocrine journal, 1995, Volume: 42, Issue:4

    Topics: Aging; Animals; Arginine; Glucagon; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Perfusion; Radioimmunoassay; Rats; Rats, Zucker

1995
Restoration of normal adult penile erectile response in aged rats by long-term treatment with androgens.
    Biology of reproduction, 1995, Volume: 53, Issue:6

    Topics: Aging; Androgens; Animals; Arginine; Blotting, Western; Dihydrotestosterone; Drug Implants; Electric Stimulation; Enzyme Inhibitors; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Penile Erection; Penis; Pressure; Rats; Rats, Inbred F344; Testosterone

1995
Beyond the somatopause: growth hormone deficiency in adults over the age of 60 years.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:2

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Body Mass Index; Female; Growth Hormone; Humans; Hypothalamic Diseases; Insulin-Like Growth Factor I; Male; Middle Aged; Pituitary Diseases; Reference Values

1996
Activation of nitric oxide synthesis in vascular smooth muscle cells and macrophages during development in spontaneously hypertensive rats.
    American journal of hypertension, 1996, Volume: 9, Issue:4 Pt 1

    Topics: Aging; Animals; Arginine; Blood Pressure; Cell Division; Cells, Cultured; Concanavalin A; Enzyme Inhibitors; Hypertension; Lymphocytes; Macrophages; Male; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Spleen

1996
Phenotypic expressions of a Gly 154Arg mutation in type II collagen in two unrelated patients with spondyloepimetaphyseal dysplasia (SEMD).
    American journal of medical genetics, 1996, May-03, Volume: 63, Issue:1

    Topics: Adult; Aging; Amino Acid Sequence; Arginine; Base Sequence; Bone and Bones; Bone Development; Collagen; Female; Genotype; Glycine; Humans; Infant, Newborn; Male; Molecular Sequence Data; Osteochondrodysplasias; Pedigree; Phenotype; Point Mutation; Polymerase Chain Reaction; Radiography; Spine

1996
Ageing is associated with reduced basal and stimulated release of nitric oxide by the coronary endothelium.
    Acta physiologica Scandinavica, 1996, Volume: 157, Issue:1

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aging; Animals; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Enzyme Inhibitors; Male; Nitric Oxide; omega-N-Methylarginine; Perfusion; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents

1996
Arg506Gln factor V mutation and cerebral ischemia in the young.
    Stroke, 1996, Volume: 27, Issue:9

    Topics: Adolescent; Adult; Aging; Arginine; Brain Ischemia; Child; Child, Preschool; Factor V; Female; Glycine; Humans; Male; Point Mutation

1996
The performance of commercial broilers when fed various levels of rendered whole-hen meal.
    Poultry science, 1996, Volume: 75, Issue:4

    Topics: Aging; Animal Feed; Animals; Arginine; Body Weight; Chickens; Diet; Eating; Food Handling; Food Preservation; Tryptophan

1996
Direct quantification of pentosidine in urine and serum by HPLC with column switching.
    Clinical chemistry, 1996, Volume: 42, Issue:9

    Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Diabetes Mellitus; Humans; Kidney Failure, Chronic; Lysine; Middle Aged; Renal Dialysis; Time Factors; Uremia

1996
The role of glycation cross-links in diabetic vascular stiffening.
    Diabetologia, 1996, Volume: 39, Issue:8

    Topics: Adult; Aged; Aging; Amino Acids; Aorta, Thoracic; Arginine; Collagen; Cross-Linking Reagents; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Elastin; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Time Factors

1996
Subcellular distribution of soluble and membrane-bound Arg-beta-naphthylamide hydrolyzing activities in the developing and aged rat brain.
    Cellular & molecular biology research, 1995, Volume: 41, Issue:5

    Topics: Aging; Aminopeptidases; Animals; Arginine; Brain; Cell Membrane; Female; Hydrolysis; Male; Microsomes; Myelin Proteins; Rats; Rats, Sprague-Dawley; Synaptosomes

1995
Comparison of 5-hydroxy-2-amino valeric acid with carbonyl group content as a marker of oxidized protein in human and mouse liver tissues.
    Free radical biology & medicine, 1996, Volume: 21, Issue:4

    Topics: Aging; Amino Acids; Animals; Arginine; Biomarkers; Carboxylic Acids; Cytosol; Gas Chromatography-Mass Spectrometry; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Proline; Proteins; Regression Analysis; Sensitivity and Specificity; Spectrometry, Mass, Secondary Ion

1996
A diet enriched in protein accelerates diabetes manifestation in NOD mice.
    Acta diabetologica, 1996, Volume: 33, Issue:3

    Topics: Aging; Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Dietary Proteins; Female; Glucose Tolerance Test; Incidence; Insulin; Insulin Secretion; Mice; Mice, Inbred NOD

1996
Arginine degradation in developing porcine enterocytes.
    The American journal of physiology, 1996, Volume: 271, Issue:5 Pt 1

    Topics: 1-Pyrroline-5-Carboxylate Dehydrogenase; Aging; Animals; Animals, Newborn; Animals, Suckling; Arginine; Cells, Cultured; Citrulline; Cyclohexanecarboxylic Acids; Intestinal Mucosa; Jejunum; Nitric Oxide Synthase; Nitroarginine; Ornithine; Ornithine Decarboxylase; Oxidoreductases Acting on CH-NH Group Donors; Proline; Pyrroline Carboxylate Reductases; Swine; Valine; Weaning

1996
Good glycaemic control reduces oxidation and glycation end-products in collagen of diabetic rats.
    Diabetologia, 1996, Volume: 39, Issue:12

    Topics: Abdomen; Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Body Weight; Collagen; Diabetes Mellitus, Type 1; Disease Models, Animal; Glycated Hemoglobin; Glycation End Products, Advanced; Glycosylation; Hydroxyproline; Hypoglycemic Agents; Insulin; Lipid Peroxidation; Lysine; Male; Oxidation-Reduction; Random Allocation; Rats; Rats, Inbred BB; Spectrometry, Fluorescence

1996
Aging-associated endothelial dysfunction in humans is reversed by L-arginine.
    Journal of the American College of Cardiology, 1996, Volume: 28, Issue:7

    Topics: Acetylcholine; Adult; Aged; Aging; Arginine; Coronary Circulation; Coronary Vessels; Endothelium, Vascular; Female; Humans; Male; Microcirculation; Middle Aged; Nitroglycerin; Papaverine; Vasodilator Agents

1996
Abdominal adiposity and physical fitness are major determinants of the age associated decline in stimulated GH secretion in healthy adults.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6

    Topics: Abdomen; Adipose Tissue; Adult; Aging; Arginine; Body Constitution; Clonidine; Female; Growth Hormone; Humans; Male; Middle Aged; Oxygen Consumption; Physical Fitness; Reference Values; Regression Analysis

1996
[Activity of basic arginine- and lysine-residue cleaving carboxypeptidase in rats of various ages].
    Biokhimiia (Moscow, Russia), 1996, Volume: 61, Issue:10

    Topics: Aging; Animals; Arginine; Brain; Carboxypeptidases; Hydrolysis; Lysine; Male; Rats

1996
Influence of dietary lysine levels and arginine:lysine ratios on performance of broilers exposed to heat or cold stress during the period of three to six weeks of age.
    Poultry science, 1997, Volume: 76, Issue:3

    Topics: Aging; Animals; Arginine; Body Composition; Body Temperature; Chickens; Cold Temperature; Diet; Dose-Response Relationship, Drug; Eating; Hot Temperature; Lysine; Male; Meat; Poultry Diseases; Regression Analysis; Stress, Physiological; Time Factors; Weight Gain

1997
Age-related increase in an advanced glycation end product in penile tissue.
    World journal of urology, 1995, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Child; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Penile Erection; Penis; Sexual Dysfunction, Physiological

1995
Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease.
    Circulation, 1997, Apr-15, Volume: 95, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Arterial Occlusive Diseases; Cyclic GMP; Disease Progression; Enzyme Inhibitors; Female; Humans; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Peripheral Vascular Diseases; Vasodilation

1997
Glucocorticoids play an important role in mediating the enhanced metabolism of arginine and glutamine in enterocytes of postweaning pigs.
    The Journal of nutrition, 1997, Volume: 127, Issue:5

    Topics: Aging; Ammonia; Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbon Dioxide; Cells, Cultured; DNA; Enzyme Induction; Female; Glucocorticoids; Glutamine; Hydrocortisone; Jejunum; Male; Mifepristone; Ornithine; Proline; Receptors, Glucocorticoid; Swine; Urea; Weaning

1997
Lysine deficiency in postweaned calves fed corn and corn gluten meal diets.
    Journal of animal science, 1997, Volume: 75, Issue:7

    Topics: Aging; Analysis of Variance; Animals; Arginine; Caseins; Cattle; Cattle Diseases; Cysteine; Deficiency Diseases; Diet; Glutamine; Glutens; Glycine; Lysine; Male; Methionine; Nitrogen; Rumen; Serine; Threonine; Zea mays

1997
Synthesis of citrulline and arginine from proline in enterocytes of postnatal pigs.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1

    Topics: Aging; Animals; Animals, Newborn; Arginine; Carbon Radioisotopes; Citrulline; Female; Intestinal Mucosa; Male; Mitochondria; Models, Biological; Ornithine; Ornithine-Oxo-Acid Transaminase; Proline; Proline Oxidase; Radioisotope Dilution Technique; Rats; Swine

1997
Basal and stimulated nitric oxide in control of kidney function in the aging rat.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Arginine; Blood Pressure; Enzyme Inhibitors; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Rats; Rats, Sprague-Dawley; Renal Circulation; Vascular Resistance; Vasoconstriction

1997
Long-term dietary supplementation with L-arginine prevents age-related reduction in renal function.
    The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 2

    Topics: Aging; Animals; Arginine; Body Weight; Cell Movement; Diet; Hemodynamics; Kidney; Kidney Glomerulus; Macrophages; Male; Nitrates; Nitrites; Organ Size; Proteinuria; Rats; Renal Circulation; Sclerosis; Time Factors

1997
Immunohistochemical localization of advanced glycation end products, pentosidine, and carboxymethyllysine in lipofuscin pigments of Alzheimer's disease and aged neurons.
    Biochemical and biophysical research communications, 1997, Jul-18, Volume: 236, Issue:2

    Topics: Adolescent; Aged; Aging; Alzheimer Disease; Arginine; Glycation End Products, Advanced; Humans; Immunohistochemistry; Lipofuscin; Lysine; Nerve Degeneration; Nerve Tissue Proteins; Neurons

1997
Aging and severity of hypertension attenuate endothelium-dependent renal vascular relaxation in humans.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:2 Pt 1

    Topics: Adult; Aged; Aging; Arginine; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Osmolar Concentration; Renal Circulation; Vasodilation

1997
[L-arginine nitric oxide pathway in acute renal ischemia reperfusion injury of the aged rats].
    Zhonghua yi xue za zhi, 1996, Volume: 76, Issue:8

    Topics: Aging; Animals; Arginine; Cyclic GMP; Ischemia; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Renal Agents; Reperfusion Injury

1996
Age-related association of tail tendon break time with tissue pentosidine in DBA/2 vs C57BL/6 mice: the effect of dietary restriction.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1997, Volume: 52, Issue:5

    Topics: Aging; Animals; Arginine; Collagen; Diet; Female; Lysine; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Protein Denaturation; Species Specificity; Tail; Tendons; Time Factors

1997
Effect of dietary aminoguanidine on tissue pentosidine and reproductive performance in broiler breeder hens.
    Poultry science, 1997, Volume: 76, Issue:11

    Topics: Aging; Analysis of Variance; Animals; Arginine; Blood Glucose; Chickens; Collagen; Diet; Egg Shell; Female; Fertility; Guanidines; Lysine; Male; Oviposition; Random Allocation; Reproduction; Skin; Specific Gravity

1997
Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen.
    Analytical biochemistry, 1997, Nov-01, Volume: 253, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Child; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Diaphyses; Dipeptides; Femur; Histidine; Humans; Indicators and Reagents; Infant; Lysine; Male; Middle Aged; Sensitivity and Specificity; Skin; Spectrometry, Fluorescence

1997
Neurochemical development of the degenerating rat retina.
    The Journal of comparative neurology, 1997, Nov-10, Volume: 388, Issue:1

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; gamma-Aminobutyric Acid; Glutamine; Glycine; Immunohistochemistry; Neurotransmitter Agents; Rats; Rats, Inbred BUF; Rats, Mutant Strains; Retina; Retinal Degeneration; Taurine

1997
Apparent ileal digestibilities of amino acids in newly weaned pigs fed diets with protease-treated soybean meal.
    Journal of animal science, 1997, Volume: 75, Issue:11

    Topics: Administration, Topical; Aging; Alanine; Amino Acids; Animals; Arginine; Diet; Dietary Proteins; Digestion; Endopeptidases; Female; Glycine max; Hydrogen-Ion Concentration; Ileum; Male; Swine; Weaning

1997
Arginine supplementation increases weight gain, depresses antibody production, and alters circulating leukocyte profiles in preruminant calves without affecting plasma growth hormone concentrations.
    Journal of animal science, 1997, Volume: 75, Issue:11

    Topics: Aging; Animals; Animals, Newborn; Antibody Formation; Arginine; Cattle; Diet; Dietary Supplements; Growth Hormone; Hemocyanins; Immunoglobulin G; Insulin-Like Growth Factor Binding Protein 3; Leukocytes; Male; Nitrogen; Radioimmunoassay; Random Allocation; Urea; Weight Gain

1997
Basal synthesis of heat shock protein 70 increases with age in rat kidneys.
    Gerontology, 1998, Volume: 44, Issue:1

    Topics: Actins; Aging; Animals; Arginine; HSP70 Heat-Shock Proteins; Kidney; Lysine; Male; Rats; Rats, Wistar; RNA, Messenger; RNA, Ribosomal

1998
Ageing and zonal variation in post-translational modification of collagen in normal human articular cartilage. The age-related increase in non-enzymatic glycation affects biomechanical properties of cartilage.
    The Biochemical journal, 1998, Feb-15, Volume: 330 ( Pt 1)

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomechanical Phenomena; Cartilage, Articular; Child; Child, Preschool; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Hydroxylysine; Infant; Lysine; Middle Aged; Protein Processing, Post-Translational

1998
Nonenzymatic glycation of cartilage proteoglycans: an in vivo and in vitro study.
    Glycoconjugate journal, 1997, Volume: 14, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Animals; Arginine; Cartilage; Cartilage, Articular; Cattle; Chromatography, Agarose; Cross-Linking Reagents; Extracellular Matrix Proteins; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Lectins, C-Type; Lysine; Middle Aged; Molecular Weight; Osteoarthritis; Proteoglycans

1997
Role of nitric oxide-related mechanisms in renal function in ageing rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1998, Volume: 13, Issue:3

    Topics: Acetylcholine; Aging; Animals; Antihypertensive Agents; Arginine; Glomerular Filtration Rate; Hemodynamics; Kidney; Kidney Function Tests; Male; Microspheres; Nitric Oxide; Nitroprusside; Rats; Rats, Wistar

1998
Role of advanced glycation end products in aging collagen. A scanning force microscope study.
    Gerontology, 1998, Volume: 44, Issue:4

    Topics: Aging; Animals; Arginine; Collagen; Glycation End Products, Advanced; Lysine; Male; Microscopy; Osmolar Concentration; Periodicity; Rats; Rats, Wistar; Tail; Tendons

1998
Collagen crosslinks in human lumbar intervertebral disc aging.
    Spine, 1998, Aug-01, Volume: 23, Issue:15

    Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cadaver; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged

1998
The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:8

    Topics: Adult; Aging; Alleles; Arginine; Body Mass Index; Body Temperature Regulation; Body Weight; Cholesterol; Cohort Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Genotype; Humans; Lipolysis; Male; Middle Aged; Obesity; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Random Allocation; Receptors, Adrenergic, beta; Tryptophan

1998
Expression of constitutive and inducible nitric oxide synthases in the vascular wall of young and aging rats.
    Circulation research, 1998, Aug-10, Volume: 83, Issue:3

    Topics: Acetylcholine; Aging; Animals; Aorta; Arginine; Blood Pressure; Bradykinin; Calcium; Cattle; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1998
Localization of identified advanced glycation end-product structures, N epsilon(carboxymethyl)lysine and pentosidine, in age-related inclusions in human brains.
    Pathology international, 1998, Volume: 48, Issue:8

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Brain; Entorhinal Cortex; Glycation End Products, Advanced; Hippocampus; Humans; Immunoenzyme Techniques; Inclusion Bodies; Lipofuscin; Lysine; Maillard Reaction; Middle Aged; Ubiquitins

1998
Influence of age, hyperglycemia, leptin, and NPY on islet blood flow in obese-hyperglycemic mice.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Hyperglycemia; Hyperinsulinism; Insulin; Insulin Secretion; Islets of Langerhans; Leptin; Mice; Mice, Inbred C57BL; Mice, Obese; Neuropeptide Y; Obesity; Organ Size; Pancreas; Perfusion; Phlorhizin; Proteins; Receptors, Leptin; Receptors, Neuropeptide Y; Regional Blood Flow

1998
Hexarelin, a synthetic GH-releasing peptide, is a powerful stimulus of GH secretion in pubertal children and in adults but not in prepubertal children and in elderly subjects.
    Journal of endocrinological investigation, 1998, Volume: 21, Issue:8

    Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Child, Preschool; Female; Growth Hormone-Releasing Hormone; Growth Substances; Human Growth Hormone; Humans; Male; Middle Aged; Oligopeptides; Puberty

1998
Determination of urinary and serum pentosidine and its application to elder patients.
    Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:10

    Topics: Adult; Aged; Aging; Arginine; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Humans; Lysine; Middle Aged

1998
Effects of continuous ambulatory peritoneal dialysis and kidney transplantation on advanced glycation endproducts in the skin and peritoneum.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Collagen; Glycation End Products, Advanced; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lysine; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritoneum; Skin; Spectrometry, Fluorescence

1998
Chemical modification of proteins by methylglyoxal.
    Cellular and molecular biology (Noisy-le-Grand, France), 1998, Volume: 44, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Animals; Aorta; Arginine; Child; Collagen; Crystallins; Diabetes Mellitus, Type 1; Dogs; Glycation End Products, Advanced; Humans; Lens, Crystalline; Lysine; Maillard Reaction; Middle Aged; Proteins; Pyruvaldehyde; Rats; Skin; Uremia

1998
Changes in collagen cross-linking in degenerative disc disease and scoliosis.
    Spine, 1998, Dec-01, Volume: 23, Issue:23

    Topics: Adolescent; Adult; Aged; Aging; Arginine; Child; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dipeptides; Extracellular Matrix; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Lysine; Middle Aged; Scoliosis

1998
Decrease in participation of nitric oxide in nonadrenergic, noncholinergic relaxation of rat intestine with age.
    Japanese journal of pharmacology, 1998, Volume: 78, Issue:3

    Topics: Adrenergic Agents; Aging; Animals; Arginine; Atropine; Colon; Electric Stimulation; Enzyme Inhibitors; Female; Guanethidine; Humans; Ileum; Immunohistochemistry; In Vitro Techniques; Infant, Newborn; Intestines; Jejunum; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Myenteric Plexus; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroarginine; Rats; Rats, Wistar; Rectum; Time Factors

1998
Prolonged L-arginine on cardiovascular mass and myocardial hemodynamics and collagen in aged spontaneously hypertensive rats and normal rats.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:1 Pt 2

    Topics: Aging; Animals; Aorta; Arginine; Collagen; Coronary Circulation; Coronary Vessels; Fibrosis; Heart; Heart Ventricles; Hemodynamics; Hypertension; Male; Muscle Development; Muscle, Smooth, Vascular; Myocardium; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reference Values; Vascular Resistance; Ventricular Function, Left

1999
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
    Biochemical and biophysical research communications, 1999, Mar-05, Volume: 256, Issue:1

    Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia

1999
Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.
    Investigative ophthalmology & visual science, 1999, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bruch Membrane; Choroid; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Glycation End Products, Advanced; Humans; Immunoenzyme Techniques; Infant; Lysine; Middle Aged; Pigment Epithelium of Eye; Retinal Drusen

1999
Protein glycosylation and advanced glycosylated endproducts (AGEs) accumulation: an avian solution?
    The journals of gerontology. Series A, Biological sciences and medical sciences, 1999, Volume: 54, Issue:4

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Enzyme Inhibitors; Female; Glycation End Products, Advanced; Glycosylation; Guanidines; Hyperglycemia; Leukocytes; Lysine; Oxidative Stress; Random Allocation; Respiratory Burst; Skin; Uric Acid

1999
Age-related decrease in proteoglycan synthesis of human articular chondrocytes: the role of nonenzymatic glycation.
    Arthritis and rheumatism, 1999, Volume: 42, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Cross-Linking Reagents; Extracellular Matrix; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Osteoarthritis; Proteoglycans; Ribose

1999
Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.
    Diabetes, 1999, Volume: 48, Issue:5

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus, Type 1; Female; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Inbred NOD

1999
Lysylhydroxylation and non-reducible crosslinking of human supraspinatus tendon collagen: changes with age and in chronic rotator cuff tendinitis.
    Annals of the rheumatic diseases, 1999, Volume: 58, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Child; Chronic Disease; Collagen; Cross-Linking Reagents; Humans; Hydroxylation; Hydroxylysine; Lysine; Middle Aged; Rotator Cuff; Tendinopathy

1999
Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.
    Molecular vision, 1999, Jul-14, Volume: 5

    Topics: Acetaldehyde; Adult; Aged; Aged, 80 and over; Aging; Animals; Antibodies; Antibody Specificity; Arginine; Bruch Membrane; Cattle; Choroid Plexus; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Immunohistochemistry; Infant; Lysine; Middle Aged

1999
Characterization and regional distribution of nitric oxide synthase in the human brain during normal ageing.
    Brain research, 1999, Jul-10, Volume: 834, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Brain; Cadaver; Child; Child, Preschool; Citrulline; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reference Values; Tissue Distribution

1999
Expression of the genes of arginine-synthesizing enzymes in the rat kidney during development.
    Biology of the neonate, 1999, Volume: 76, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Blotting, Northern; Gene Expression; Glucocorticoids; Intestines; Kidney; Liver; Rats; Rats, Wistar; RNA, Messenger; Tissue Distribution; Transcription, Genetic

1999
DNA sequence variants of p53: cancer and aging.
    American journal of human genetics, 1999, Volume: 65, Issue:6

    Topics: Aged; Aged, 80 and over; Aging; Arginine; Codon; Genes, p53; Genetic Predisposition to Disease; Genetic Variation; Genotype; Haplotypes; Humans; Middle Aged; Neoplasms; Odds Ratio; Polymorphism, Genetic; Proline

1999
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo.
    The international journal of biochemistry & cell biology, 1999, Volume: 31, Issue:11

    Topics: Aging; Animals; Antioxidants; Arabinose; Arginine; Cattle; Cross-Linking Reagents; Diabetes Mellitus; Fluorescence; Glucose; In Vitro Techniques; Lysine; Maillard Reaction; Oxidation-Reduction; Oxygen; Pentoses; Proteins; Ribonucleases

1999
Adult and fetal haemoglobin J-Sardegna [alpha50(CE8)His-->Asp]: functional and molecular modelling studies.
    The Biochemical journal, 2000, Feb-15, Volume: 346 Pt 1

    Topics: 2,3-Diphosphoglycerate; Adult; Aging; Amino Acid Substitution; Arginine; Aspartic Acid; Binding Sites; Computer Simulation; Crystallography, X-Ray; Fetal Blood; Genetic Variation; Hemoglobin J; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Models, Molecular; Oxygen; Temperature; Thermodynamics; Time Factors

2000
Effect of age and menopause on serum concentrations of pentosidine, an advanced glycation end product.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2000, Volume: 55, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Biomarkers; Bone and Bones; Bone Remodeling; Collagen; Cross-Linking Reagents; Female; Glycation End Products, Advanced; Humans; Lysine; Menopause; Middle Aged; Osteocalcin

2000
Accumulation of advanced glycation endproducts in aging male Fischer 344 rats during long-term feeding of various dietary carbohydrates.
    The Journal of nutrition, 2000, Volume: 130, Issue:5

    Topics: Aging; Animals; Arginine; Blood Glucose; Collagen; Cross-Linking Reagents; Dietary Carbohydrates; Dietary Sucrose; Energy Intake; Fructosamine; Fructose; Glucose; Glycation End Products, Advanced; Lysine; Male; Rats; Rats, Inbred F344; Skin; Starch

2000
Arginine enhances In vivo immune responses in young, adult and aged mice.
    The Journal of nutrition, 2000, Volume: 130, Issue:7

    Topics: Aging; Animals; Arginine; Body Weight; Dietary Supplements; Hypersensitivity, Delayed; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Organ Size

2000
Age-related accumulation of Maillard reaction products in human articular cartilage collagen.
    The Biochemical journal, 2000, Sep-01, Volume: 350 Pt 2

    Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Arginine; Cartilage, Articular; Child; Child, Preschool; Collagen; Collagenases; Cross-Linking Reagents; Female; Femur; Glycation End Products, Advanced; Humans; Lysine; Maillard Reaction; Male; Middle Aged; Skin; Spectrometry, Fluorescence

2000
Decrease of neuronal nitric oxide synthase in the cerebellum of aged rats.
    Neuroscience letters, 2000, Sep-08, Volume: 291, Issue:1

    Topics: Aging; Animals; Arginine; Blotting, Northern; Blotting, Western; Cerebellum; Citrulline; Densitometry; Electrophoresis, Polyacrylamide Gel; Glyceraldehyde-3-Phosphate Dehydrogenases; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; RNA, Messenger

2000
Acceleration of pubertal development following central blockade of the Y1 subtype of neuropeptide Y receptors.
    Regulatory peptides, 2000, Nov-24, Volume: 95, Issue:1-3

    Topics: Aging; Animals; Arginine; Body Weight; Female; Hypothalamus; Luteinizing Hormone; Neuropeptide Y; Pituitary Gland; Rats; Rats, Wistar; Receptors, Neuropeptide Y; Sexual Maturation; Vagina; Weight Gain

2000
Age-related variations in the neuroendocrine control, more than impaired receptor sensitivity, cause the reduction in the GH-releasing activity of GHRPs in human aging.
    Pituitary, 1998, Volume: 1, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Dose-Response Relationship, Drug; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Male; Neurosecretory Systems; Oligopeptides

1998
Growth hormone deficiency in elderly patients with hypothalamo-pituitary tumors.
    Pituitary, 1998, Volume: 1, Issue:1

    Topics: Aged; Aging; Arginine; Body Composition; Bone Density; Case-Control Studies; Collagen; Collagen Type I; Female; Growth Hormone-Releasing Hormone; Human Growth Hormone; Humans; Hypothalamic Neoplasms; Insulin; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Middle Aged; Osteocalcin; Peptides; Pituitary Neoplasms

1998
Upregulation of the nitric oxide-cGMP pathway in aged myocardium: physiological response to l-arginine.
    Circulation research, 2001, Jan-19, Volume: 88, Issue:1

    Topics: Aging; Animals; Arginine; Cyclic GMP; Dose-Response Relationship, Drug; Female; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Signal Transduction; Up-Regulation

2001
Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis.
    American journal of medical genetics, 2000, Dec-11, Volume: 95, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acid Substitution; Arginine; Arteriosclerosis; Coronary Artery Disease; Cysteine; Finland; Gene Frequency; Genotype; Haplotypes; Humans; Infant, Newborn; Leucine; Longevity; Mexico; Middle Aged; Phenylalanine; Polymorphism, Genetic; Werner Syndrome

2000
Isoleucine imbalance using selected mixtures of imbalancing amino acids in diets of the broiler chick.
    Poultry science, 2000, Volume: 79, Issue:12

    Topics: Aging; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Composition; Chickens; Diet; Dietary Proteins; Eating; Isoleucine; Lysine; Male; Nutritional Requirements; Regression Analysis; Weight Gain

2000
Contrasting effects of L-arginine on insulin-mediated blood flow and glucose disposal in the elderly.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:2

    Topics: Adult; Aged; Aging; Anthropometry; Arginine; Blood Flow Velocity; Blood Glucose; Blood Pressure; Electric Conductivity; Female; Glucose Clamp Technique; Heart Rate; Humans; Infusions, Intravenous; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Nitric Oxide; Vasodilation

2001
Modest overexpression of neuropeptide Y in the brain leads to obesity after high-sucrose feeding.
    Diabetes, 2001, Volume: 50, Issue:5

    Topics: Aging; Animals; Arginine; Brain; Cyclohexanes; Dietary Sucrose; Energy Intake; Homozygote; Humans; Mice; Mice, Knockout; Mice, Transgenic; Neuropeptide Y; Obesity; Phenotype; Promoter Regions, Genetic; Receptors, Neuropeptide Y; Reference Values; Thy-1 Antigens; Xanthenes

2001
Endogenous nitric oxide-mediated relaxation and nitrinergic innervation in the rabbit prostate: the changes with aging.
    The Prostate, 2001, Jun-15, Volume: 48, Issue:1

    Topics: Aging; Aminoquinolines; Animals; Arginine; Atropine; Electric Stimulation; Guanethidine; Histocytochemistry; In Vitro Techniques; Indomethacin; Male; Muscle Tonus; Muscle, Smooth; NADPH Dehydrogenase; Nerve Fibers; Nitric Oxide; Organ Size; Propranolol; Prostate; Rabbits; Tetrodotoxin; Tissue Distribution

2001
Accelerated tissue aging and increased oxidative stress in broiler chickens fed allopurinol.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2001, Volume: 129, Issue:2

    Topics: Aging; Allopurinol; Animals; Antimetabolites; Arginine; Blood Glucose; Body Weight; Chickens; Cross-Linking Reagents; Diet; Glycation End Products, Advanced; Glycosylation; Hemin; Luminescent Measurements; Lysine; Muscle, Skeletal; Oxidative Stress; Skin; Uric Acid

2001
Elevated serum endogenous inhibitor of nitric oxide synthase and endothelial dysfunction in aged rats.
    Clinical and experimental pharmacology & physiology, 2001, Volume: 28, Issue:10

    Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Endothelium, Vascular; Kidney; Male; Nitric Oxide Synthase; Nitrites; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2001
Reduction in asymmetrical dimethylarginine, an endogenous nitric oxide synthase inhibitor, in the cerebrospinal fluid during aging and in patients with Alzheimer's disease.
    Neuroscience letters, 2001, Oct-26, Volume: 312, Issue:3

    Topics: Aged; Aging; Alzheimer Disease; Arginine; Brain; Female; Humans; Male; Middle Aged; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress

2001
Augmented age-associated innate immune responses contribute to negative inotropic and lusitropic effects of lipopolysaccharide and interferon gamma.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:10

    Topics: Adrenergic beta-Agonists; Age Factors; Aging; Animals; Arginine; Blotting, Western; Citrulline; Cyclic AMP; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunity; Interferon-gamma; Isoproterenol; Lipopolysaccharide Receptors; Lipopolysaccharides; Lysine; Nitric Oxide; Rats; Rats, Wistar; Sepsis; Signal Transduction; Up-Regulation

2001
Maturation-dependent neointima formation in fowl aorta.
    Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 2001, Volume: 130, Issue:1

    Topics: Actins; Aging; Animals; Aorta, Abdominal; Arginine; Asparagine; Blood Pressure; Chickens; Cholesterol; Female; Hyperplasia; Male; Microscopy, Electron; Muscle, Smooth, Vascular; Myosin Heavy Chains; Nitric Oxide; Ornithine; Phenylalanine; Tunica Intima

2001
Age-related accumulation of the advanced glycation endproduct pentosidine in human articular cartilage aggrecan: the use of pentosidine levels as a quantitative measure of protein turnover.
    Matrix biology : journal of the International Society for Matrix Biology, 2001, Volume: 20, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aggrecans; Aging; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chondroitin Sulfate Proteoglycans; Extracellular Matrix Proteins; Glycation End Products, Advanced; Humans; Lectins, C-Type; Lysine; Middle Aged; Osteoarthritis; Proteoglycans

2001
Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: the role of advanced glycation end products.
    Arthritis and rheumatism, 2001, Volume: 44, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Aging; Animals; Arginine; Arthritis, Rheumatoid; Cartilage, Articular; Cattle; Chromatography, High Pressure Liquid; Glycosaminoglycans; Humans; In Vitro Techniques; Knee Joint; Lysine; Matrix Metalloproteinases; Middle Aged; Osteoarthritis, Knee; Phenylmercuric Acetate; Ribose; Synovial Fluid

2001
Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:12

    Topics: Aging; Animals; Arginine; Brain Chemistry; Creatinine; Glycine; Guanidines; Homoarginine; Humans; Hypertrophy; Kidney; Male; Mice; Mice, Inbred C57BL; Nephrectomy; Succinates; Urea

2001
Isolated systolic hypertension in elderly WKY is reversed with L-arginine and ACE inhibition.
    Hypertension (Dallas, Tex. : 1979), 2001, Dec-01, Volume: 38, Issue:6

    Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Collagen; Coronary Circulation; Hemodynamics; Hypertension; Kidney; Male; Myocardium; Organ Size; Rats; Rats, Inbred WKY; Regional Blood Flow; Vascular Resistance; Ventricular Function, Left

2001
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:1

    Topics: Adult; Aging; Arginine; Cartilage, Articular; Collagen; Cross-Linking Reagents; Glycation End Products, Advanced; Humans; Lysine; Osteoarthritis; Pyruvaldehyde; Regression Analysis; Ribose; Stress, Mechanical; Tetroses

2002
[Levels of mature cross-links and advanced glycation end product cross-links in human vitreous].
    Nippon Ganka Gakkai zasshi, 2002, Volume: 106, Issue:1

    Topics: Adult; Aged; Aging; Amino Acids; Arginine; Cross-Linking Reagents; Diabetes Mellitus; Glycation End Products, Advanced; Humans; Lysine; Middle Aged; Vitreous Body

2002
Long-term high-fat feeding leads to severe insulin resistance but not diabetes in Wistar rats.
    American journal of physiology. Endocrinology and metabolism, 2002, Volume: 282, Issue:6

    Topics: Acyl Coenzyme A; Aging; Animals; Arginine; Blood Glucose; Body Composition; Diabetes Mellitus; Dietary Fats; Fasting; Genetic Predisposition to Disease; Glucose Clamp Technique; Glucose Intolerance; Glucose Tolerance Test; Glycogen; Insulin; Insulin Resistance; Liver; Male; Muscle, Skeletal; Rats; Rats, Wistar; Time Factors; Triglycerides; Weight Gain

2002
The 'intestinal-renal' arginine biosynthetic axis in the aging rat.
    Mechanisms of ageing and development, 2002, Apr-30, Volume: 123, Issue:8

    Topics: Aging; Animals; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Cerebellum; Citrulline; Female; Glutaminase; Intestine, Small; Kidney; Kidney Cortex; Male; Ornithine Carbamoyltransferase; Rats; Rats, Sprague-Dawley

2002
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function.
    Circulation research, 2002, Jun-14, Volume: 90, Issue:11

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Aging; Animals; Arginine; Arterioles; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Coronary Vessels; Enzyme Inhibitors; Fatty Acids, Unsaturated; Hydrazines; Immunohistochemistry; In Vitro Techniques; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Phenotype; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Superoxide Dismutase; Tyrosine; Vasodilation; Xanthine Oxidase

2002
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians.
    European journal of human genetics : EJHG, 2002, Volume: 10, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Alleles; Amino Acid Substitution; Arginine; Aryldialkylphosphatase; Esterases; Female; Gene Frequency; Humans; Longevity; Male

2002
Effect of age on bone mineral density and the serum concentration of endogenous nitric oxide synthase inhibitors in rats.
    Comparative medicine, 2002, Volume: 52, Issue:3

    Topics: Absorptiometry, Photon; Aging; Animals; Arginine; Bone and Bones; Bone Density; Enzyme Inhibitors; Male; Malondialdehyde; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley

2002
[Investigations on the plasm amino acids of old patients with rheumatoid arthritis (author's transl)].
    Aktuelle Gerontologie, 1977, Volume: 7, Issue:12

    Topics: Aged; Aging; Amino Acids; Arginine; Arthritis, Rheumatoid; Chromatography, Ion Exchange; Cystathionine; Humans; Methylhistidines; Middle Aged; Threonine; Tryptophan

1977
Postnatal amino acid uptake by the rat small intestine. Changes in membrane transport systems for amino acids associated with maturation of jejunal morphology.
    Journal of developmental physiology, 1979, Volume: 1, Issue:2

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Biological Transport, Active; gamma-Aminobutyric Acid; In Vitro Techniques; Intestinal Mucosa; Jejunum; Kinetics; Leucine; Lysine; Methionine; Phenylalanine; Rats; Valine

1979
Age related activity changes in arginine phosphokinase in the house fly, Musca domestic+ L.
    Journal of gerontology, 1975, Volume: 30, Issue:2

    Topics: Aging; Animals; Arginine; Cytoplasm; Female; Flight, Animal; Houseflies; Male; Phosphotransferases; Sex Factors

1975
Age-dependent arginine phosphokinase activity changes in male vestigial and wild-type Drosophila melanogaster.
    Gerontologia, 1975, Volume: 21, Issue:4

    Topics: Aging; Animals; Arginine; Drosophila melanogaster; Female; Flight, Animal; Male; Muscles; Mutation; Phosphotransferases

1975
Effect of aging on free amino acids and electrolytes in leg skeletal muscle.
    Clinical science (London, England : 1979), 1979, Volume: 56, Issue:5

    Topics: Aged; Aging; Alanine; Amino Acids; Arginine; Citrulline; Electrolytes; Histidine; Humans; Leg; Male; Middle Aged; Muscles; Water

1979
Orotic aciduria and increased nitrogen catabolism in rats.
    The Journal of nutrition, 1979, Volume: 109, Issue:11

    Topics: Aging; Animals; Arginine; Dietary Proteins; Male; Nitrogen; Orotic Acid; Purine-Pyrimidine Metabolism, Inborn Errors; Rats; Starvation

1979
Effect of growth & differentiation on distribution of arginase & arginine in rat tissues.
    Indian journal of biochemistry & biophysics, 1979, Volume: 16, Issue:2

    Topics: Aging; Animals; Arginase; Arginine; Growth; Liver Neoplasms, Experimental; Liver Regeneration; Male; Rats

1979
Ontogenetic changes in the content of methylated amino acids in rodent skeletal muscle.
    Experimental gerontology, 1977, Volume: 12, Issue:5-6

    Topics: Aging; Animals; Arginine; Cricetinae; Histidine; Lysine; Male; Methylation; Methylhistidines; Mice; Muscle Development; Muscles; Myosins; Rats

1977
[Raised glucagon levels of the blood induced by arginine: relation to blood sugar, blood insulin and STH in aged non-diabetics and diabetics].
    Minerva medica, 1978, Apr-14, Volume: 69, Issue:18

    Topics: Adult; Age Factors; Aged; Aging; Arginine; Blood Glucose; Diabetes Mellitus; Glucagon; Growth Hormone; Humans; Insulin

1978
Orotic aciduria in the female rat and its relation to dietary arginine.
    The Journal of nutrition, 1978, Volume: 108, Issue:8

    Topics: Aging; Ammonia; Animals; Arginine; Birth Weight; Body Weight; Citrates; Female; Litter Size; Orotic Acid; Pregnancy; Pregnancy Complications; Rats; Species Specificity; Urea

1978
[Effects of ageing on arginine-induced secretion of insulin (author's transl)].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1978, Volume: 15, Issue:6

    Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Female; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Male; Middle Aged

1978
Insulin and growth hormone in lean and obese pigs.
    The American journal of physiology, 1977, Volume: 233, Issue:2

    Topics: Aging; Animals; Arginine; Blood Glucose; Fasting; Glucose; Growth Hormone; Insulin; Obesity; Swine

1977
Insect flight muscle: maturation and senescence.
    Gerontology, 1976, Volume: 22, Issue:4

    Topics: Age Factors; Aging; Animals; Arginine; Female; Flight, Animal; Glycogen; Insecta; Male; Mitochondria, Muscle; Muscles; Oxidoreductases; Sex Factors

1976
Oxygen-mediated regulation of neonatal and adult rabbit aortic tension.
    Developmental pharmacology and therapeutics, 1992, Volume: 19, Issue:2-3

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aging; Animals; Aorta; Arginine; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Isoquinolines; Muscle Contraction; Muscle Development; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Oxygen; Piperazines; Potassium Chloride; Protein Kinase C; Rabbits

1992
Possible mechanisms of age-associated reduction of vascular relaxation caused by atrial natriuretic peptide.
    European journal of pharmacology, 1992, Jan-07, Volume: 210, Issue:1

    Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Aging; Animals; Aorta, Thoracic; Arginine; Atrial Natriuretic Factor; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; In Vitro Techniques; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinones; Rats; Rats, Inbred Strains

1992
Involvement of nitric oxide pathway in the PAF-induced relaxation of rat thoracic aorta.
    British journal of pharmacology, 1992, Volume: 107, Issue:1

    Topics: Aging; Animals; Aorta, Thoracic; Arginine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Guanylate Cyclase; Hemoglobins; Male; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Platelet Activating Factor; Pyridinium Compounds; Rats; Rats, Wistar

1992
Developmental changes in endothelium-dependent pulmonary vasodilatation in pigs.
    British journal of pharmacology, 1992, Volume: 106, Issue:2

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Arginine; Dinoprost; Endothelium, Vascular; In Vitro Techniques; Masoprocol; Microscopy, Electron; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitroprusside; omega-N-Methylarginine; Pulmonary Artery; Swine; Vasodilation

1992
A neuroendocrinological approach to evidence an impairment of central cholinergic function in aging.
    Journal of endocrinological investigation, 1992, Volume: 15, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypothalamo-Hypophyseal System; Insulin-Like Growth Factor I; Male; Pituitary Gland; Pyridostigmine Bromide

1992
[Influences of hypercholesterolemia on the vessel function of isolated rat thoracic aorta].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 99, Issue:3

    Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Arginine; Body Weight; Cholesterol, Dietary; Endothelium, Vascular; Hypercholesterolemia; In Vitro Techniques; Male; Muscle, Smooth, Vascular; omega-N-Methylarginine; Phenylephrine; Piperidines; Pyrimidinones; Rats; Rats, Inbred Strains; Vasoconstriction

1992
Pattern of thyrotropin-releasing hormone secretion from the adult and neonatal rat pancreas: comparison with insulin secretion.
    Endocrinology, 1992, Volume: 130, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Arginine; Cells, Cultured; Chromatography, Gel; Female; Gene Expression; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Pregnancy; Protein Precursors; Radioimmunoassay; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone

1992
GH response to GHRH, insulin, clonidine and arginine after GHRH pretreatment in children.
    Acta endocrinologica, 1992, Volume: 126, Issue:2

    Topics: Adolescent; Aging; Arginine; Child; Child, Preschool; Clonidine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Insulin; Male

1992
Exercise training delineates the importance of B-cell dysfunction to the glucose intolerance of human aging.
    The Journal of clinical endocrinology and metabolism, 1992, Volume: 74, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Bicycling; Blood Glucose; Exercise; Glucose Tolerance Test; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Middle Aged; Running

1992
Impairment of L-arginine metabolism in spontaneously hypertensive rats.
    Biochemistry international, 1992, Volume: 26, Issue:4

    Topics: Aging; Animals; Arginine; Hypertension; Immersion; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Stress, Physiological

1992
Fluorophores from aging human articular cartilage.
    Journal of biochemistry, 1991, Volume: 110, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aging; Amino Acids; Arginine; Cartilage, Articular; Chemical Fractionation; Child; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Female; Humans; Lysine; Male; Microbial Collagenase; Middle Aged; Solubility; Spectrometry, Fluorescence

1991
Effects of different regimens of dietary restriction on the age-related decline in insulin secretory response of isolated rat pancreatic islets.
    Annals of the New York Academy of Sciences, 1991, Volume: 621

    Topics: 1-Methyl-3-isobutylxanthine; Aging; Animals; Arginine; Diet, Reducing; Energy Intake; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Male; Potassium Chloride; Rats; Rats, Inbred Strains; Reference Values

1991
Arginine-deficient diets alter plasma and tissue amino acids in young and aged rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:10

    Topics: Aging; Amino Acids; Ammonia; Animals; Arginine; Diet; Liver; Male; Orotic Acid; Rats; Rats, Inbred Strains; Spleen

1991
The effects of overeating on insulin secretion in normal mice.
    Diabetes research (Edinburgh, Scotland), 1991, Volume: 17, Issue:3

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Cacao; Diet; Feeding and Eating Disorders; Glucose; Glucose Tolerance Test; Glycated Hemoglobin; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Mice, Inbred ICR; Perfusion; Reference Values

1991
Dietary arginine supplementation does not enhance lymphocyte proliferation or interleukin-2 production in young and aged rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:8

    Topics: Aging; Alanine; Animals; Arginine; Body Weight; Citrulline; Concanavalin A; Diet; Glutamine; Interleukin-2; Lymphocyte Activation; Male; Organ Size; Ornithine; Phytohemagglutinins; Pokeweed Mitogens; Rats; Rats, Inbred F344; Spleen

1991
Alterations of biochemical and biomechanical properties of rat tail tendons caused by non-enzymatic glycation and their inhibition by dibasic amino acids arginine and lysine.
    Diabetologia, 1991, Volume: 34, Issue:1

    Topics: Aging; Animals; Arginine; Fructosamine; Glucose; Glycosylation; Hexosamines; In Vitro Techniques; Kinetics; Lysine; Male; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Stress, Mechanical; Tail; Tendons

1991
NG-monomethyl-L-arginine-induced pressor response at developmental and established stages in spontaneously hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Acetylcholine; Aging; Animals; Arginine; Blood Pressure; Heart Rate; Injections, Intravenous; Male; omega-N-Methylarginine; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity

1991
Development of pyrroline-5-carboxylate synthase and N-acetylglutamate synthase and their changes in lactation and aging.
    Archives of biochemistry and biophysics, 1991, Nov-15, Volume: 291, Issue:1

    Topics: Acetyltransferases; Aging; Amino-Acid N-Acetyltransferase; Animals; Arginine; Female; Intestine, Small; Kinetics; Lactation; Liver; Ornithine-Oxo-Acid Transaminase; Pregnancy; Rats; Rats, Inbred Strains; Urea

1991
High correlation between pentosidine protein crosslinks and pigmentation implicates ascorbate oxidation in human lens senescence and cataractogenesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Nov-15, Volume: 88, Issue:22

    Topics: Adult; Aged; Aging; Animals; Arginine; Ascorbic Acid; Cataract; Cattle; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Crystallins; Humans; Hydrolysis; Lens, Crystalline; Lysine; Models, Biological; Molecular Weight; Pigmentation; Reference Values

1991
Age-related decrease in plasma growth hormone: response to growth hormone-releasing hormone, arginine, and L-dopa in obesity.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:12

    Topics: Adolescent; Adult; Aged; Aging; Arginine; Female; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Levodopa; Male; Middle Aged; Obesity

1991
Lifelong sequential changes in glucose tolerance and insulin secretion in genetically obese Zucker rats (fa/fa) fed a diabetogenic diet.
    Endocrinology, 1991, Volume: 128, Issue:2

    Topics: Aging; Animals; Arginine; Blood Glucose; Diabetes Mellitus; Diet; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Longitudinal Studies; Obesity; Rats; Rats, Zucker

1991
Gradual delay in glucose-induced first phase insulin secretion by the pancreatic islets of 7 week-, 6 month-, and 1 year-old rats.
    Journal of gerontology, 1991, Volume: 46, Issue:2

    Topics: Aging; Animals; Arginine; Calcium; Culture Techniques; Cytosol; Dose-Response Relationship, Drug; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Male; Potassium; Rats; Rats, Inbred Strains; Time Factors

1991
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes.
    Diabetes, 1991, Volume: 40, Issue:4

    Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; In Vitro Techniques; Islets of Langerhans; Male; Perfusion; Rats; Rats, Inbred Strains; Rats, Mutant Strains; Reference Values

1991
Maturational changes in endothelium-derived relaxing factor activity of ovine pulmonary arteries in vitro.
    The American journal of physiology, 1991, Volume: 260, Issue:4 Pt 1

    Topics: Acetylcholine; Adenosine Diphosphate; Aging; Animals; Animals, Newborn; Arginine; Female; Gestational Age; In Vitro Techniques; Kinetics; Muscle Development; Muscle, Smooth, Vascular; Nitric Oxide; Nitroprusside; Pregnancy; Pulmonary Artery; Sheep; Vasodilation; Vasodilator Agents

1991
Growth hormone (GH) responsiveness to combined administration of arginine and GH-releasing hormone does not vary with age in man.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aging; Arginine; Drug Synergism; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Kinetics; Male

1990
[The effect of intravenous administration of arginine and glycine on the blood plasma content of glucose, insulin, free fatty acids and total alpha-amino-N-compounds in lambs of different ages].
    Archiv fur experimentelle Veterinarmedizin, 1990, Volume: 44, Issue:3

    Topics: Aging; Animals; Arginine; Blood Glucose; Fatty Acids, Nonesterified; Glycine; Insulin; Sheep

1990
Activation of endothelial L-arginine pathway in resistance arteries. Effect of age and hypertension.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 16, Issue:2

    Topics: Acetylcholine; Aging; Animals; Arginine; Endothelium, Vascular; Hypertension; Male; Nitric Oxide; Norepinephrine; omega-N-Methylarginine; Phenylephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Resistance; Vasoconstriction

1990
Implication of lysine residues in the loss of enzymatic activity in rat liver 6-phosphogluconate dehydrogenase found in aging.
    The Journal of biological chemistry, 1989, Oct-15, Volume: 264, Issue:29

    Topics: Aging; Animals; Arginine; Ascorbic Acid; Chemical Phenomena; Chemistry, Physical; Histidine; Immunosorbent Techniques; Liver; Lysine; Methionine; Molecular Weight; Oxidation-Reduction; Peptide Fragments; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains; Sulfhydryl Compounds

1989
Insulin, growth hormone, glucose, and fatty acids in gilts selected for rapid vs. slow growth rate.
    The American journal of physiology, 1989, Volume: 257, Issue:4 Pt 1

    Topics: Aging; Animals; Arginine; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose; Growth Hormone; Growth Hormone-Releasing Hormone; Insulin; Species Specificity; Swine

1989
[Immunoreactive 7B2 concentrations in plasma and cerebrospinal fluid in pathophysiological conditions and the responses to oral glucose load, intravenous LH-RH, TRH and arginine infusion].
    Nihon Naibunpi Gakkai zasshi, 1989, Oct-20, Volume: 65, Issue:10

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Arginine; Cerebrovascular Disorders; Child; Child, Preschool; Female; Fetal Blood; Glucose; Gonadotropin-Releasing Hormone; Humans; Infant; Infusions, Intravenous; Injections, Intravenous; Kidney Failure, Chronic; Male; Middle Aged; Nerve Tissue Proteins; Neuroendocrine Secretory Protein 7B2; Pituitary Hormones; Pregnancy; Thyrotropin-Releasing Hormone

1989
Structure elucidation of a senescence cross-link from human extracellular matrix. Implication of pentoses in the aging process.
    The Journal of biological chemistry, 1989, Dec-25, Volume: 264, Issue:36

    Topics: Aging; Animals; Arginine; Cells, Cultured; Chromatography, Gel; Chromatography, High Pressure Liquid; Collagen; Cross-Linking Reagents; Dura Mater; Extracellular Matrix; Hexoses; Humans; Lysine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Organ Specificity; Pentoses; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1989
Plasma glucagon-immunoreactive components in early life in dogs.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:8

    Topics: Aging; Animals; Animals, Newborn; Arginine; Dogs; Glucagon; Glucagon-Like Peptides; Insulin; Peptides; Radioimmunoassay; Somatostatin

1985
Adenylate energy charge, arginine phosphate and ATPase activity in juvenile Homarus americanus during the molt cycle.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1985, Volume: 81, Issue:3

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aging; Animals; Arginine; Energy Metabolism; Gills; Liver; Muscle Development; Nephropidae; Organ Specificity; Pancreas; Sodium-Potassium-Exchanging ATPase

1985
[The effect of synthetic human pancreatic growth hormone-releasing factor (hpGRF-44) on serum growth hormone response in normal and obese subjects].
    Nihon Naibunpi Gakkai zasshi, 1986, Feb-20, Volume: 62, Issue:2

    Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Female; Follicle Stimulating Hormone; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hydrocortisone; Insulin; Luteinizing Hormone; Male; Middle Aged; Obesity; Peptide Fragments; Prolactin; Thyrotropin

1986
Recovery of age-related decline of thymic endocrine activity and PHA response by lysin-arginine combination.
    International journal of immunopharmacology, 1986, Volume: 8, Issue:7

    Topics: Aging; Amino Acids; Animals; Arginine; Cytotoxicity Tests, Immunologic; Lysine; Male; Mice; Mice, Inbred BALB C; Phytohemagglutinins; Thymic Factor, Circulating; Thymus Gland; Thymus Hormones

1986
Possible involvement of histidine residues in the loss of enzymatic activity of rat liver malic enzyme during aging.
    The Journal of biological chemistry, 1988, Jun-15, Volume: 263, Issue:17

    Topics: Aging; Animals; Arginine; Histidine; Kinetics; Liver; Lysine; Malate Dehydrogenase; Methionine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds

1988
Effect of age on the insulin secretory response of perfused rat pancreas to arginine and tolbutamide.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1987, Volume: 19, Issue:10

    Topics: Aging; Animals; Arginine; Body Weight; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Organ Size; Perfusion; Radioimmunoassay; Rats; Tolbutamide

1987
In vitro response to mitogens and antigens in elderly and post-cytotoxic patients can be modified by a new hypoxanthine derivative (PCF-39).
    Bollettino dell'Istituto sieroterapico milanese, 1987, Volume: 66, Issue:6

    Topics: Aged; Aging; Antineoplastic Agents; Arginine; Diabetes Mellitus, Type 2; Humans; Hypoxanthines; Immunity, Cellular; Lymphocyte Activation; Melanoma; Phytohemagglutinins

1987
Age-related differences in the incorporation of 3H-arginine into vasopressin in Fischer 344 rats.
    Experimental gerontology, 1987, Volume: 22, Issue:2

    Topics: Aging; Animals; Arginine; Arginine Vasopressin; Biological Transport, Active; Hypothalamus; Kinetics; Male; Pituitary Gland, Posterior; Rats; Rats, Inbred F344

1987
Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased beta-cell function.
    The Journal of clinical endocrinology and metabolism, 1985, Volume: 60, Issue:1

    Topics: Adipose Tissue; Adolescent; Adult; Aged; Aging; Arginine; Blood Glucose; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Resistance; Islets of Langerhans; Kinetics; Male; Middle Aged

1985
Carbohydrate intolerance in gonadal dysgenesis: evidence for insulin resistance and hyperglucagonemia.
    Hormone research, 1985, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Aging; Arginine; Blood Glucose; Body Weight; Child; Glucagon; Glucose Tolerance Test; Gonadal Dysgenesis; Growth Hormone; Humans; Insulin; Insulin Resistance; Malabsorption Syndromes; Male; Obesity; Tolbutamide

1985
Analysis of immunoreactive insulins in man in relation to the effects of aging.
    Biochemical medicine, 1985, Volume: 34, Issue:2

    Topics: Adult; Aged; Aging; Arginine; Blood Glucose; Blood Proteins; Fasting; Humans; Immunoelectrophoresis; Insulin; Islets of Langerhans; Middle Aged; Proinsulin

1985
Ontogeny modifies manifestations of cystinuria genes: implications for counseling.
    The Journal of pediatrics, 1985, Volume: 106, Issue:3

    Topics: Aging; Amino Acids; Arginine; Cystinuria; Follow-Up Studies; Genetic Counseling; Genotype; Humans; Infant, Newborn; Lysine; Ornithine; Phenotype; Quebec

1985
Effect of arginine-free diet on ammonia metabolism in young and adult ferrets.
    The Journal of nutrition, 1986, Volume: 116, Issue:4

    Topics: Aging; Ammonia; Animals; Arginine; Benzoates; Benzoic Acid; Brain; Brain Diseases; Diet; Ferrets; Male

1986
Nutritional and metabolic responses to arginine deficiency in carnivores.
    The Journal of nutrition, 1985, Volume: 115, Issue:4

    Topics: Aging; Animal Nutritional Physiological Phenomena; Animals; Arginine; Carnivora; Cats; Citrulline; Dogs; Glutamine; Intestinal Mucosa; Kidney; Liver; Muscles; Nutritional Requirements; Ornithine; Ornithine-Oxo-Acid Transaminase; Orotic Acid; Rats; Species Specificity; Urea

1985
Methylation of myelin basic protein by enzymes from rat brain.
    Journal of neurochemistry, 1974, Volume: 23, Issue:6

    Topics: Adenosine; Aging; Animals; Arginine; Brain; Carbon Radioisotopes; Cell Nucleus; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytoplasm; Homocysteine; Methylation; Methyltransferases; Microsomes; Mitochondria; Myelin Basic Protein; Myelin Sheath; Rats; Ribosomes; S-Adenosylmethionine; Time Factors; Tritium; Ultrafiltration

1974
Biochemical aspects of the aging of the sea mussel Mytilus gallo-provincialis.
    Experientia, 1974, Feb-15, Volume: 30, Issue:2

    Topics: Adenosine Triphosphatases; Aging; Animals; Arginine; Bivalvia; Chick Embryo; Muscles

1974
Insulin secretion during development: response of isolated pancreatic islets of fetal, newborn and adult rats to theophylline and arginine.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1972, Volume: 4, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Antigens; Arginine; Female; Fetus; Glucose; Immunoassay; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Microbial Collagenase; Rats; Stimulation, Chemical; Theophylline

1972
Hydrolytic enzyme activities in the developing chick central and peripheral nervous systems.
    Journal of neurochemistry, 1974, Volume: 23, Issue:5

    Topics: Aging; Aminopeptidases; Animals; Arginine; Brain; Chick Embryo; Chickens; Glutamates; Leucyl Aminopeptidase; Lysine; Naphthols; Nucleotides, Cyclic; Phosphoric Diester Hydrolases; Sciatic Nerve; Time Factors

1974
On the water economy of Israel amphibians; the anurans.
    Comparative biochemistry and physiology. A, Comparative physiology, 1971, Volume: 40, Issue:4

    Topics: Aging; Animals; Anura; Arginine; Bufonidae; Kinetics; Oxytocin; Ranidae; Skin; Sweating; Temperature; Urinary Bladder; Vasotocin; Water; Water Loss, Insensible; Xenopus

1971
Fetal development: the effects of maturation on in vitro protein synthesis by mouse brain tissue.
    Journal of neurochemistry, 1974, Volume: 23, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Arginine; Brain; Carbon Radioisotopes; Cell-Free System; Centrifugation, Density Gradient; Deoxycholic Acid; Female; Fetus; Gestational Age; In Vitro Techniques; Magnesium; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Phenylalanine; Polyribosomes; Pregnancy; Time Factors

1974
Further data on the age-dependent intestinal absorption of dibasic amino acids.
    Experimental gerontology, 1974, Volume: 9, Issue:5-6

    Topics: Aging; Amino Acids; Animals; Arginine; Biological Transport; Carbon Radioisotopes; Female; Intestinal Absorption; Intestines; Lysine; Organ Size; Rats

1974
[Proceedings: Effects of aging on arginine induction of insulin secretion].
    Nihon Naibunpi Gakkai zasshi, 1974, Feb-20, Volume: 50, Issue:2

    Topics: Adult; Aged; Aging; Arginine; Female; Humans; Insulin; Male; Middle Aged

1974
Changes in transfer RNAs and aminoacyl-tRNA synthetases during sea urchin development.
    Biochimica et biophysica acta, 1973, Jul-27, Volume: 312, Issue:4

    Topics: Aging; Amino Acyl-tRNA Synthetases; Animals; Arginine; Carbon Isotopes; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Embryo, Nonmammalian; Female; Fertilization; Leucine; Lysine; Ovum; RNA, Transfer; Saccharomyces cerevisiae; Sea Urchins; Serine; Spectrophotometry, Ultraviolet; Time Factors; Tritium

1973
Effect of age on growth hormone secretion in man.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 37, Issue:1

    Topics: Adipose Tissue; Adult; Aged; Aging; Arginine; Blood Glucose; Body Composition; Fasting; Glucose; Growth Hormone; Humans; Male; Middle Aged; Potassium Isotopes

1973
Synthesis and degradation of chicken liver xanthine dehydrogenase during development.
    Mechanisms of ageing and development, 1973, Volume: 1, Issue:5

    Topics: Aging; Alcohol Oxidoreductases; Animals; Arginine; Carbon Isotopes; Chick Embryo; Chickens; Chromatography, Ion Exchange; Electrophoresis, Disc; Kinetics; Liver; Methods; Valine

1973
Gluconeogenesis in the newborn rat: the substrates and their quantitative significance.
    Enzyme, 1973, Volume: 15, Issue:1

    Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginase; Arginine; Dietary Fats; Female; Gluconeogenesis; Glycerol; Glycogen; L-Lactate Dehydrogenase; Lactates; Lactation; Ligases; Lipid Metabolism; Liver; Mitochondria, Liver; Pregnancy; Pyruvates; Rats; Succinates; Urea

1973
Free amino acids in developing rat retina.
    Journal of neurochemistry, 1974, Volume: 22, Issue:6

    Topics: Aging; Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Chromatography, Ion Exchange; Glutamates; Glutamine; Glycine; Histidine; Methionine; Ornithine; Proline; Rats; Retina; Taurine; Time Factors; Tyrosine

1974
[Aortic elastin and its variations during senescence and arteriosclerosis].
    Pathologie-biologie, 1970, Volume: 18, Issue:1

    Topics: Aging; Amino Acids; Animals; Aorta; Arginine; Arteriosclerosis; Aspartic Acid; Cattle; Elastin; Glutamates; Lysine; Rabbits

1970
Age-related alterations in the structure of nucleoprotein. IV. Changes in the compoistion of whole histone from rat liver.
    Gerontologia, 1969, Volume: 15, Issue:4

    Topics: Age Factors; Aging; Animals; Arginine; DNA; Edetic Acid; Female; Histones; Immunodiffusion; Liver; Lysine; Methods; Nucleoproteins; Rats; Temperature

1969
Biochemical studies on the aging of rat tail tendon.
    Gerontologia, 1971, Volume: 17, Issue:2

    Topics: Aging; Animals; Arginine; Calcium Chloride; Collagen; Fucose; Galactose; Glucose; Glycoproteins; Glycosides; Hexosamines; Hexoses; Hydroxyproline; Lysine; Mannose; Proteins; Rats; Tail; Tendons; Time Factors; Xylose

1971
Preparation of two antigens of human liver isoenzymes of alkaline phosphatase.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 34, Issue:3

    Topics: Aging; Alkaline Phosphatase; Antibody Formation; Antigens; Arginine; Chromatography, Gel; Depression, Chemical; Humans; Immune Sera; Immunoelectrophoresis; Isoenzymes; Liver; Magnesium; Phenylalanine; Stimulation, Chemical

1971
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1966, Dec-15, Volume: 171, Issue:3

    Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine

1966
The effect of catechol amines on free amino acids in rat heart and other organs.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: Aging; Alanine; Amino Acids; Animals; Arginine; Epinephrine; Female; Glutamates; Glutamine; Heart; Liver; Metabolism; Myocardium; Norepinephrine; Ornithine; Rats; Reserpine; Time Factors

1969
The biosynthesis of protamine in trout testis. II. Polysome patterns and protein synthetic activities during testis maturation.
    The Journal of biological chemistry, 1970, Volume: 245, Issue:12

    Topics: Aging; Animals; Arginine; Carbon Isotopes; Centrifugation, Density Gradient; Cytoplasm; Dactinomycin; Liver; Lysine; Magnesium; Male; Protamines; Ribonucleases; Ribosomes; Salmonidae; Seasons; Testis; Ultracentrifugation

1970
Estrogen-induced variation of lysine transfer ribonucleic acid isoacceptors in chicken liver.
    Biochimica et biophysica acta, 1970, Dec-14, Volume: 224, Issue:2

    Topics: Aging; Albumins; Animals; Arginine; Chickens; Chromatography; Detergents; Diethylstilbestrol

1970
Intestinal transfer of l-arginine in relation to age.
    Experimental gerontology, 1970, Volume: 5, Issue:3

    Topics: Aging; Animals; Arginine; Carbon Isotopes; Female; Intestinal Absorption; Intestine, Small; Rats

1970
Metabolic changes in the tissues of young and old mice. Oxygen consumption with different substrates.
    Experimental gerontology, 1968, Volume: 3, Issue:4

    Topics: Aging; Animals; Arginine; Brain; Glutamates; Kidney; Malates; Manometry; Mice; Myocardium; Oxygen Consumption

1968
Studies on the histones and DNA of calf and old cow thymus.
    Journal of gerontology, 1968, Volume: 23, Issue:4

    Topics: Aging; Animals; Arginine; Cattle; Centrifugation, Density Gradient; Cesium; Chromosomes; DNA; Histocytochemistry; Histones; Lysine; Molecular Biology; Spectrophotometry; Thymus Gland

1968