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arecoline and Tremor

arecoline has been researched along with Tremor in 20 studies

Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"The muscarinic agonist arecoline (6 mg/kg, subcutaneously in mice) induced a long-lasting tremor."7.74[Involvement of ionotropic glutamate receptors in the genesis of arecoline-induced tremor]. ( Gmiro, VE; Lavrent'eva, VV; Lukomskaia, NIa; Magazanik, LG; Starshinova, LA; Zhabko, EP, 2007)
"Two oxotremorine antagonists have been examined using oxotremorine as the tremor salivation inducer and the ratios between the central and peripheral nervous systems determined."7.65The central and peripheral effectiveness of two oxotremorine-antagonists determined using oxotremorine-induced tremor and salivation. ( Eicholzer, A; Ogren, SO, 1977)
"Injection of rats with 14C-labelled nicotine (3 mg/kg sc) resulted in tremor measured by an electronic device during the first minutes after the injection."7.65Nicotine induced tremor and antidiuresis and brain nicotine levels in the rat. ( Mansner, R; Mattila, MJ, 1975)
" Both types of blocker weakened arecoline tremor, though the dose-response relationships were different for mono-and dications."5.35Involvement of ionotropic glutamate receptors in the appearance of arecoline tremor in mice. ( Gmiro, VE; Lavrent'eva, VV; Lukomskaya, NY; Magazanik, LG; Starshinova, LA; Zhabko, EP, 2008)
"The muscarinic agonist arecoline (6 mg/kg, subcutaneously in mice) induced a long-lasting tremor."3.74[Involvement of ionotropic glutamate receptors in the genesis of arecoline-induced tremor]. ( Gmiro, VE; Lavrent'eva, VV; Lukomskaia, NIa; Magazanik, LG; Starshinova, LA; Zhabko, EP, 2007)
"A tropane ester, three tropane ethers, atropine and mecamylamine were compared in mice for their anti-muscarinic and anti-nicotinic activity against arecoline-induced tremor and nicotine-induced convulsions, respectively."3.69Anticholinergic activity in mice and receptor-binding properties in rats of a series of synthetic tropane derivatives. ( Cui, WY; Gao, ZG; Liu, BY; Liu, CG; Wang, L, 1997)
"Experiments on male Wistar rats and Icr:Icl mice studied the influence of the novel compound--amino acid-containing 1,4-dihydropyridine derivative glutapyrone (G) on acute generalized seizures, arecoline and nicotine tremor, and 45Ca2+ uptake in brain synaptosomes."3.68[The anticonvulsant properties of glutapyrone--a new type of derivative of amino acid-containing 1,4-dihydropyridines]. ( Bisenieks, EA; Cebers, G; Duburs, GIa; Germane, SK; Karpova, MN; Klusa, VE; Pankov, OIu, 1993)
" However, no correlation was found between antistereotypic effect of neuroleptics and their ability to block 3H-quinuclidinyl benzylate binding or arecoline-induced tremor."3.67[Significance of the dopamine-blocking and m-choline-blocking components in the antiapomorphine action of neuroleptics]. ( Chereshka, KS; Langel, IuL; Zharkovskaia, TA; Zharkovskiĭ, AM, 1987)
"The dose-effect of oxotremorine upon the onset, duration and magnitude of tremor and salivation was studied in both mice and rats."3.67Serotonergic potentiation of muscarinic agonist evoked tremor and salivation in rat and mouse. ( Bartfai, T; Carlsson, S; Ogren, SO, 1985)
"Two oxotremorine antagonists have been examined using oxotremorine as the tremor salivation inducer and the ratios between the central and peripheral nervous systems determined."3.65The central and peripheral effectiveness of two oxotremorine-antagonists determined using oxotremorine-induced tremor and salivation. ( Eicholzer, A; Ogren, SO, 1977)
"Injection of rats with 14C-labelled nicotine (3 mg/kg sc) resulted in tremor measured by an electronic device during the first minutes after the injection."3.65Nicotine induced tremor and antidiuresis and brain nicotine levels in the rat. ( Mansner, R; Mattila, MJ, 1975)
" Both types of blocker weakened arecoline tremor, though the dose-response relationships were different for mono-and dications."1.35Involvement of ionotropic glutamate receptors in the appearance of arecoline tremor in mice. ( Gmiro, VE; Lavrent'eva, VV; Lukomskaya, NY; Magazanik, LG; Starshinova, LA; Zhabko, EP, 2008)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's4 (20.00)18.2507
2000's4 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bromidge, SM1
Brown, F1
Cassidy, F1
Clark, MS1
Dabbs, S1
Hadley, MS1
Hawkins, J1
Loudon, JM1
Naylor, CB1
Orlek, BS1
Riley, GJ1
ZEJMAL, EV1
VOTAVA, Z1
Magazanik, LG3
Tikhonov, DB1
Tikhonova, TB1
Lukomskaya, NY2
Nannan, G1
Runmei, Y1
Fusheng, L1
Shoulan, Z1
Guangqing, L1
Lukomskaia, NIa1
Lavrent'eva, VV2
Starshinova, LA2
Zhabko, EP2
Gmiro, VE2
Karpova, MN1
Germane, SK1
Cebers, G1
Pankov, OIu1
Klusa, VE1
Duburs, GIa1
Bisenieks, EA1
Gao, ZG1
Cui, WY1
Liu, BY1
Liu, CG1
Wang, L1
Pandit, PR1
Kulkarni, S1
Joglekar, GV1
Eicholzer, A1
Ogren, SO2
Mansner, R1
Mattila, MJ1
Eichmann, H1
Andreas, K1
Westermann, KH1
Böttger, G1
Polinsky, RJ1
Brown, RT1
Curras, MT1
Baser, SM1
Baucom, CE1
Hooper, DR1
Marini, AM1
Gomita, Y1
Suemaru, K1
Furuno, K1
Araki, Y1
Zharkovskiĭ, AM1
Langel, IuL1
Chereshka, KS1
Zharkovskaia, TA1
Retz, KC1
Trimmer, CK1
Forster, MJ1
Lal, H1
Carlsson, S1
Bartfai, T1
Gothoni, P1
Soncrant, TT1
Holloway, HW1
Rapoport, SI1
Costall, B1
Naylor, RJ1
Olley, JE1

Other Studies

20 other studies available for arecoline and Tremor

ArticleYear
Design of [R-(Z)]-(+)-alpha-(methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitri le (SB 202026), a functionally selective azabicyclic muscarinic M1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere.
    Journal of medicinal chemistry, 1997, Dec-19, Volume: 40, Issue:26

    Topics: Alzheimer Disease; Animals; Binding Sites; Blood Pressure; Brain; CHO Cells; Cricetinae; Electroence

1997
Antagonism against the arecoline tremors of oxyphenonium and its tertiary analogue after intravenous and intracerebral administration in mice.
    Experientia, 1961, Oct-15, Volume: 17

    Topics: Administration, Intravenous; Animals; Arecoline; Mice; Oxyphenonium; Tremor

1961
Mechanisms of the blockade of glutamate channel receptors: significance for structural and physiological investigations.
    Neuroscience and behavioral physiology, 2007, Volume: 37, Issue:3

    Topics: Animals; Animals, Newborn; Arecoline; Diamines; Disease Models, Animal; Drug Interactions; Excitator

2007
Effects of AIT-082, a purine derivative, on tremor induced by arecoline or oxotremorine in mice.
    Pharmacology, 2007, Volume: 80, Issue:1

    Topics: Aminobenzoates; Animals; Arecoline; Dose-Response Relationship, Drug; Hypoxanthines; Male; Mice; Mic

2007
[Involvement of ionotropic glutamate receptors in the genesis of arecoline-induced tremor].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2007, Volume: 93, Issue:3

    Topics: Animals; Arecoline; Cholinergic Agonists; Dose-Response Relationship, Drug; Mice; Receptors, AMPA; R

2007
Involvement of ionotropic glutamate receptors in the appearance of arecoline tremor in mice.
    Neuroscience and behavioral physiology, 2008, Volume: 38, Issue:4

    Topics: Adamantane; Animals; Arecoline; Cyclohexylamines; Excitatory Amino Acid Antagonists; Mice; Quaternar

2008
[The anticonvulsant properties of glutapyrone--a new type of derivative of amino acid-containing 1,4-dihydropyridines].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 116, Issue:9

    Topics: Animals; Anticonvulsants; Arecoline; Calcium; Cerebral Cortex; Dihydropyridines; Drug Evaluation, Pr

1993
Anticholinergic activity in mice and receptor-binding properties in rats of a series of synthetic tropane derivatives.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:3

    Topics: Animals; Arecoline; Brain; Drug Antagonism; Female; Male; Mice; Muscarinic Agonists; Muscarinic Anta

1997
Comparative study of central and peripheral anticholinergic activities of antihistaminics in vivo in albino mice.
    Indian journal of medical sciences, 1975, Volume: 29, Issue:12

    Topics: Animals; Arecoline; Female; Histamine H1 Antagonists; Humans; Hyperkinesis; Male; Mice; Nicotine; Pa

1975
The central and peripheral effectiveness of two oxotremorine-antagonists determined using oxotremorine-induced tremor and salivation.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:10

    Topics: Alkynes; Animals; Arecoline; Male; Mice; Oxotremorine; Pyrrolidinones; Salivation; Time Factors; Tre

1977
Nicotine induced tremor and antidiuresis and brain nicotine levels in the rat.
    Medical biology, 1975, Volume: 53, Issue:3

    Topics: Animals; Arecoline; Brain; Cotinine; Depression, Chemical; Diuresis; Drug Interactions; Kidney; Live

1975
[A method for the objective determination of tremors in the rat].
    Acta biologica et medica Germanica, 1975, Volume: 34, Issue:3

    Topics: Animals; Arecoline; Electromyography; Electronics; Methods; Rats; Tremor

1975
Central and peripheral effects of arecoline in patients with autonomic failure.
    Journal of neurology, neurosurgery, and psychiatry, 1991, Volume: 54, Issue:9

    Topics: Adrenocorticotropic Hormone; Arecoline; Autonomic Nervous System; Autonomic Nervous System Diseases;

1991
Nicotine-induced tail-tremor and drug effects.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 34, Issue:4

    Topics: Animals; Arecoline; Atropine; Hexamethonium; Hexamethonium Compounds; Male; Mecamylamine; Nicotine;

1989
[Significance of the dopamine-blocking and m-choline-blocking components in the antiapomorphine action of neuroleptics].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:3

    Topics: Animals; Antipsychotic Agents; Apomorphine; Arecoline; Choline; Dopamine Antagonists; Female; Male;

1987
Motor responses of autoimmune NZB/B1NJ and C57BL/6Nnia mice to arecoline and nicotine.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:2

    Topics: Animals; Arecoline; Dose-Response Relationship, Drug; Male; Mecamylamine; Mice; Mice, Inbred C57BL;

1987
Serotonergic potentiation of muscarinic agonist evoked tremor and salivation in rat and mouse.
    Psychopharmacology, 1985, Volume: 86, Issue:3

    Topics: Alanine; Animals; Arecoline; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Oxo

1985
Ethanol withdrawal tremor does not interact with physostigmine-induced tremor in rat.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 23, Issue:3

    Topics: Animals; Arecoline; Atropine; Ethanol; Male; Physostigmine; Rats; Rats, Inbred Strains; Substance Wi

1985
Arecoline-induced elevations of regional cerebral metabolism in the conscious rat.
    Brain research, 1985, Nov-18, Volume: 347, Issue:2

    Topics: Animals; Arecoline; Auditory Cortex; Behavior, Animal; Blood Pressure; Brain; Brain Chemistry; Cereb

1985
Catalepsy and circling behaviour after intracerebral injections of neuroleptic, cholinergic and anticholinergic agents into the caudate-putamen, globus pallidus and substantia nigra of rat brain.
    Neuropharmacology, 1972, Volume: 11, Issue:5

    Topics: Animals; Arecoline; Atropine; Behavior, Animal; Catalepsy; Caudate Nucleus; Corpus Striatum; Diffusi

1972