Page last updated: 2024-10-22

arecoline and Schizophrenia

arecoline has been researched along with Schizophrenia in 6 studies

Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"Cerebral demyelination is possibly one of the main pathological factors involved in the development of schizophrenia."5.51Arecoline attenuates memory impairment and demyelination in a cuprizone-induced mouse model of schizophrenia. ( Adilijiang, A; He, J; Li, X; Lin, D; Wang, W; Xu, Z; You, P, 2019)
"We reviewed the clinical literature data since 1980 via a PubMed search for the terms: arecoline, arecaidine, guvacine, guvacoline, betel, Areca catechu, positive and negative symptoms, cognitive symptoms, psychosis and schizophrenia in combination."4.88Potential action of betel alkaloids on positive and negative symptoms of schizophrenia: a review. ( Coppola, M; Mondola, R, 2012)
"Cerebral demyelination is possibly one of the main pathological factors involved in the development of schizophrenia."1.51Arecoline attenuates memory impairment and demyelination in a cuprizone-induced mouse model of schizophrenia. ( Adilijiang, A; He, J; Li, X; Lin, D; Wang, W; Xu, Z; You, P, 2019)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xu, Z1
Adilijiang, A1
Wang, W1
You, P1
Lin, D1
Li, X1
He, J1
Coppola, M1
Mondola, R1
FULCHER, JH1
GALLAGHER, WJ1
PFEIFFER, CC1
Sullivan, RJ1
Allen, JS1
Otto, C1
Tiobech, J1
Nero, K1
Burton-Bradley, BG1
Deahl, M1

Reviews

1 review available for arecoline and Schizophrenia

ArticleYear
Potential action of betel alkaloids on positive and negative symptoms of schizophrenia: a review.
    Nordic journal of psychiatry, 2012, Volume: 66, Issue:2

    Topics: Alkaloids; Areca; Arecoline; Cholinergic Agents; Humans; Male; Phytotherapy; Schizophrenia; Schizoph

2012

Other Studies

5 other studies available for arecoline and Schizophrenia

ArticleYear
Arecoline attenuates memory impairment and demyelination in a cuprizone-induced mouse model of schizophrenia.
    Neuroreport, 2019, 01-16, Volume: 30, Issue:2

    Topics: Animals; Arecoline; Chelating Agents; Cholinergic Agonists; Cuprizone; Demyelinating Diseases; Disea

2019
Comparative lucid intervals after amobarbital, CO2, and arecoline in the chronic schizophrenic.
    A.M.A. archives of neurology and psychiatry, 1957, Volume: 78, Issue:4

    Topics: Amobarbital; Arecoline; Carbon Dioxide; Humans; Parasympathomimetics; Schizophrenia

1957
Effects of chewing betel nut (Areca catechu) on the symptoms of people with schizophrenia in Palau, Micronesia.
    The British journal of psychiatry : the journal of mental science, 2000, Volume: 177

    Topics: Adult; Areca; Arecoline; Cholinergic Agonists; Cross-Sectional Studies; Diagnosis, Dual (Psychiatry)

2000
Arecaidine and schizophrenia.
    The American journal of psychiatry, 1978, Volume: 135, Issue:4

    Topics: Areca; Arecoline; Asia; Humans; Medicine, Traditional; Phytotherapy; Plants, Medicinal; Schizophreni

1978
Betel nut-induced extrapyramidal syndrome: an unusual drug interaction.
    Movement disorders : official journal of the Movement Disorder Society, 1989, Volume: 4, Issue:4

    Topics: Antipsychotic Agents; Areca; Arecoline; Basal Ganglia Diseases; Drug Interactions; Drug Therapy, Com

1989