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arecoline and Renal Insufficiency, Chronic

arecoline has been researched along with Renal Insufficiency, Chronic in 1 studies

Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.

Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)

Research Excerpts

ExcerptRelevanceReference
"Arecoline treatment upregulated the expression of phosphorylated extracellular signal-regulated kinase through epithelial mesenchymal transition and renal fibrosis in HK2 cells."1.56Arecoline induces epithelial mesenchymal transition in HK2 cells by upregulating the ERK-mediated signaling pathway. ( Cheng, CW; Hsieh, YH; Lee, CC; Lee, CH; Lin, SH; Syu, RJ; Tsai, JP, 2020)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Hsieh, YH1
Syu, RJ1
Lee, CC1
Lin, SH1
Lee, CH1
Cheng, CW1
Tsai, JP1

Other Studies

1 other study available for arecoline and Renal Insufficiency, Chronic

ArticleYear
Arecoline induces epithelial mesenchymal transition in HK2 cells by upregulating the ERK-mediated signaling pathway.
    Environmental toxicology, 2020, Volume: 35, Issue:9

    Topics: Actins; Antigens, CD; Areca; Arecoline; Cadherins; Cell Cycle; Cell Line; Cell Movement; Dose-Respon

2020