arecoline has been researched along with Pregnancy in 12 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Higher doses of arecoline inhibit endothelial cell growth, which suggest that long-term use or high doses of areca nut might induce endothelial dysfunction and associated diseases." | 1.33 | Effects of arecoline in relaxing human umbilical vessels and inhibiting endothelial cell growth. ( Hsiao, KM; Kuo, FC; Lo, YC; Wang, YY; Wu, DC; Yang, YC; Yuan, SS, 2005) |
| " After several pilot dose-response studies, we administered 8 mg of the cholinergic agonist arecoline subcutaneously to eight pairs of normal volunteer identical twins and eight bipolar patients currently euthymic and unmedicated." | 1.27 | Behavioral, physiological, and neuroendocrine responses to arecoline in normal twins and "well state" bipolar patients. ( Gershon, ES; Gillin, JC; Jimerson, DC; Lawrence, D; Nadi, NS; Nurnberger, JI; Simmons-Alling, S; Sitaram, N; Tamminga, C, 1983) |
| " Positive results were obtained and a linear dose-response relationship was expressed when pregnant mice were treated with arecoline at dose levels of 20, 40 and 80 mg/kg and micronucleated polychromatic erythrocytes from fetal blood were subsequently analysed." | 1.27 | Transplacental micronucleus inducing ability of arecoline, a betel nut alkaloid, in mice. ( Rao, AR; Sinha, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peng, WH | 1 |
| Lee, YC | 2 |
| Chau, YP | 1 |
| Lu, KS | 1 |
| Kung, HN | 1 |
| Shih, YT | 1 |
| Chen, PS | 1 |
| Wu, CH | 1 |
| Tseng, YT | 1 |
| Wu, YC | 1 |
| Lo, YC | 2 |
| Liu, ST | 1 |
| Young, GC | 1 |
| Chang, YF | 1 |
| Pichini, S | 4 |
| Pellegrini, M | 3 |
| Pacifici, R | 3 |
| Marchei, E | 3 |
| Murillo, J | 2 |
| Puig, C | 3 |
| Vall, O | 3 |
| García-Algar, O | 4 |
| Alameda, F | 1 |
| Zuccaro, P | 2 |
| Kuo, FC | 1 |
| Wu, DC | 1 |
| Yuan, SS | 1 |
| Hsiao, KM | 1 |
| Wang, YY | 1 |
| Yang, YC | 1 |
| Durgbanshi, A | 1 |
| Rossi, S | 1 |
| Nurnberger, JI | 1 |
| Jimerson, DC | 1 |
| Simmons-Alling, S | 1 |
| Tamminga, C | 1 |
| Nadi, NS | 1 |
| Lawrence, D | 1 |
| Sitaram, N | 1 |
| Gillin, JC | 1 |
| Gershon, ES | 1 |
| Shalaby, IA | 1 |
| Spear, LP | 1 |
| Kurihara-Bergstrom, T | 1 |
| Good, WR | 1 |
| Signor, C | 1 |
| Woodworth, M | 1 |
| Sinha, A | 1 |
| Rao, AR | 1 |
12 other studies available for arecoline and Pregnancy
| Article | Year |
|---|---|
Short-term exposure of zebrafish embryos to arecoline leads to retarded growth, motor impairment, and somite muscle fiber changes.
Topics: Animals; Arecoline; Cholinergic Agonists; Embryo, Nonmammalian; Female; Humans; Models, Animal; Moto | 2015 |
Arecoline, a major alkaloid of the areca nut, causes neurotoxicity through enhancement of oxidative stress and suppression of the antioxidant protective system.
Topics: Animals; Antioxidants; Apoptosis; Areca; Arecoline; Caspases; Cell Death; Cytochromes c; Female; Glu | 2010 |
A preliminary report on the toxicity of arecoline on early pregnancy in mice.
Topics: Animals; Arecoline; Female; Litter Size; Mice; Mice, Inbred ICR; Pregnancy; Teratogens | 2011 |
Quantification of arecoline (areca nut alkaloid) in neonatal biological matrices by high-performance liquid chromatography/electrospray quadrupole mass spectrometry.
Topics: Adult; Arecoline; Calibration; Chromatography, High Pressure Liquid; Female; Fetal Blood; Humans; In | 2003 |
Prenatal exposure to arecoline (areca nut alkaloid) and birth outcomes.
Topics: Areca; Arecoline; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Meconium; Neonatal Absti | 2005 |
Assessment of exposure to opiates and cocaine during pregnancy in a Mediterranean city: preliminary results of the "Meconium Project".
Topics: Abortion, Induced; Adult; Arecoline; Body Height; Cholinergic Agonists; Cocaine; Dopamine Uptake Inh | 2005 |
Effects of arecoline in relaxing human umbilical vessels and inhibiting endothelial cell growth.
Topics: Areca; Arecoline; Blotting, Western; Cell Proliferation; Cells, Cultured; Dose-Response Relationship | 2005 |
Determination of arecoline (areca nut alkaloid) and nicotine in hair by high-performance liquid chromatography/electrospray quadrupole mass spectrometry.
Topics: Areca; Arecoline; Chromatography, High Pressure Liquid; Female; Hair; Humans; Illicit Drugs; Infant, | 2005 |
Behavioral, physiological, and neuroendocrine responses to arecoline in normal twins and "well state" bipolar patients.
Topics: Arecoline; Bipolar Disorder; Emotions; Female; Glycopyrrolate; Growth Hormone; Humans; Hydrocortison | 1983 |
Chronic administration of haloperidol during development: later psychopharmacological responses to apomorphine and arecoline.
Topics: Animals; Apomorphine; Arecoline; Behavior, Animal; Catalepsy; Female; Haloperidol; Humans; Male; Pre | 1980 |
Epidermal differentiation and permeability in fetal pig skin.
Topics: Animals; Arecoline; Cell Differentiation; Epidermal Cells; Female; Fetus; Gestational Age; Hydrogen- | 1990 |
Transplacental micronucleus inducing ability of arecoline, a betel nut alkaloid, in mice.
Topics: Animals; Arecoline; Cell Nucleus; Dose-Response Relationship, Drug; Erythrocytes; Female; Fetal Bloo | 1985 |