arecoline has been researched along with Necrosis in 1 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arecoline is cytotoxic via necrosis for endothelium, while biochemical assays indicate no appreciable cellular leakage before death and detachment, as well as no clear effect on mitochondrial function in viable cells." | 3.80 | Arecoline is cytotoxic for human endothelial cells. ( Boadle, R; Cox, S; Kelly, E; Ullah, M; Zoellner, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ullah, M | 1 |
| Cox, S | 1 |
| Kelly, E | 1 |
| Boadle, R | 1 |
| Zoellner, H | 1 |
1 other study available for arecoline and Necrosis
| Article | Year |
|---|---|
Arecoline is cytotoxic for human endothelial cells.
Topics: Arecoline; Autophagy; Cell Count; Cell Culture Techniques; Cell Survival; Cholinergic Agonists; Colo | 2014 |