Page last updated: 2024-10-22

arecoline and Lymph Node Metastasis

arecoline has been researched along with Lymph Node Metastasis in 7 studies

Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.

Research Excerpts

ExcerptRelevanceReference
"Arecoline treatment dose dependently induced Lin28B expression in SG and FaDu cells."1.42Elevated Lin28B expression is correlated with lymph node metastasis in oral squamous cell carcinomas. ( Chou, MY; Lin, WT; Shieh, TM; Wang, TY; Yang, LC; Yu, CC, 2015)
"Arecoline was also found to induced Snail expression in a dose- and time-dependent manner (p<0."1.39Elevated snail expression mediates tumor progression in areca quid chewing-associated oral squamous cell carcinoma via reactive oxygen species. ( Chang, YC; Lee, SS; Tsai, CH; Yu, CC, 2013)
"Arecoline was found to elevate MGMT expression in a dose- and time-dependent manner."1.39The expression of O(6) -methylguanine-DNA methyltransferase in human oral keratinocytes stimulated with arecoline. ( Chang, YC; Ho, YC; Hsu, HI; Lee, SS; Tsai, CH; Yu, CC, 2013)
"Arecoline was found to elevate HSP47 expression in a dose- and time-dependent manner (P<0."1.37Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells. ( Chang, YC; Lee, SS; Li, YC; Tsai, CH; Tseng, LH, 2011)
"Arecoline was found to elevate HSP70 expression in a dose- and time-dependent manner (p<0."1.35The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas. ( Chang, YC; Ho, YC; Lee, SS; Tsai, CH, 2008)
"Argyrophilic carcinoids were found in 2 Syrian hamsters (Mesocricetus auratus)."1.25Argyrophilic carcinoids in two Syrian hamsters (Mesocricetus auratus). ( Dunham, LJ; Snell, KC; Stewart, HL, 1975)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Ren, H1
He, G1
Lu, Z1
He, Q1
Li, S1
Huang, Z1
Chen, Z1
Cao, C1
Wang, A1
Lee, SS4
Tsai, CH4
Yu, CC3
Chang, YC4
Lin, WT1
Shieh, TM1
Yang, LC1
Wang, TY1
Chou, MY1
Tseng, LH1
Li, YC1
Ho, YC2
Hsu, HI1
Dunham, LJ1
Snell, KC1
Stewart, HL1

Other Studies

7 other studies available for arecoline and Lymph Node Metastasis

ArticleYear
Arecoline induces epithelial-mesenchymal transformation and promotes metastasis of oral cancer by SAA1 expression.
    Cancer science, 2021, Volume: 112, Issue:6

    Topics: Animals; Arecoline; Cell Line, Tumor; Cell Movement; Cytokines; Epithelial-Mesenchymal Transition; G

2021
Elevated snail expression mediates tumor progression in areca quid chewing-associated oral squamous cell carcinoma via reactive oxygen species.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Areca; Arecoline; Carcinoma, Squamous Cell; Cells, Cultured; Disease

2013
Elevated Lin28B expression is correlated with lymph node metastasis in oral squamous cell carcinomas.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2015, Volume: 44, Issue:10

    Topics: Adult; Aged; Arecoline; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement

2015
Heat shock protein 47 expression in oral squamous cell carcinomas and upregulated by arecoline in human oral epithelial cells.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2011, Volume: 40, Issue:5

    Topics: Acetylcysteine; Areca; Arecoline; Carcinoma, Squamous Cell; Case-Control Studies; Cell Line, Tumor;

2011
The expression of O(6) -methylguanine-DNA methyltransferase in human oral keratinocytes stimulated with arecoline.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:8

    Topics: Areca; Arecoline; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line; Cholinergic Agonists; Dose

2013
The upregulation of heat shock protein 70 expression in areca quid chewing-associated oral squamous cell carcinomas.
    Oral oncology, 2008, Volume: 44, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Areca; Arecoline; Blotting, Western; Carcinoma, Squamous Cell; C

2008
Argyrophilic carcinoids in two Syrian hamsters (Mesocricetus auratus).
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:2

    Topics: Animals; Arecoline; Calcium Hydroxide; Carcinoid Tumor; Cricetinae; Diet; Liver Neoplasms; Lymphatic

1975