arecoline has been researched along with Innate Inflammatory Response in 5 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Keratinocyte inflammation is crucial for the pathogenesis of cancer and tissue fibrosis." | 5.32 | Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. ( Chan, CP; Chang, MC; Chiang, BL; Hahn, LJ; Ho, YS; Jeng, JH; Lee, JJ; Lee, PH; Wang, TM; Wang, YJ, 2003) |
| " The M1 receptor agonists aceclidine and arecholine and the nonspecific muscarinic receptor agonist oxotremorine augmented carrageenin oedema, an effect attenuated by the M1 receptor antagonist scopolamine." | 3.68 | Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats. ( Bhattacharya, SK; Das Gupta, G; Sen, AP; Seth, K; Seth, PK, 1991) |
| "Keratinocyte inflammation is crucial for the pathogenesis of cancer and tissue fibrosis." | 1.32 | Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. ( Chan, CP; Chang, MC; Chiang, BL; Hahn, LJ; Ho, YS; Jeng, JH; Lee, JJ; Lee, PH; Wang, TM; Wang, YJ, 2003) |
| " The dose-response curves of these compounds in the former were shifted to the right and/or abolished, suggesting decreased sensitivity of LEW/N hypothalami to these neurotransmitters." | 1.28 | Neurotransmitter-induced hypothalamic-pituitary-adrenal axis responsiveness is defective in inflammatory disease-susceptible Lewis rats: in vivo and in vitro studies suggesting globally defective hypothalamic secretion of corticotropin-releasing hormone. ( Aksentijevich, S; Bagdy, G; Bernardini, R; Calogero, AE; Chrousos, GP; Gold, PW; Smith, C; Sternberg, EM; Wilder, RL, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, RJ | 1 |
| Pan, ZY | 1 |
| Long, CL | 1 |
| Cui, WY | 1 |
| Zhang, YF | 1 |
| Wang, H | 1 |
| Jeng, JH | 2 |
| Wang, YJ | 1 |
| Chiang, BL | 1 |
| Lee, PH | 2 |
| Chan, CP | 1 |
| Ho, YS | 1 |
| Wang, TM | 1 |
| Lee, JJ | 2 |
| Hahn, LJ | 2 |
| Chang, MC | 2 |
| Wu, HL | 1 |
| Chang, HH | 1 |
| Lin, BR | 1 |
| Chen, YJ | 1 |
| Calogero, AE | 1 |
| Sternberg, EM | 1 |
| Bagdy, G | 1 |
| Smith, C | 1 |
| Bernardini, R | 1 |
| Aksentijevich, S | 1 |
| Wilder, RL | 1 |
| Gold, PW | 1 |
| Chrousos, GP | 1 |
| Bhattacharya, SK | 1 |
| Sen, AP | 1 |
| Das Gupta, G | 1 |
| Seth, K | 1 |
| Seth, PK | 1 |
5 other studies available for arecoline and Innate Inflammatory Response
| Article | Year |
|---|---|
Stimulation of non-neuronal muscarinic receptors enhances chemerin/ChemR23 system in dysfunctional endothelial cells.
Topics: Adipokines; Animals; Aorta, Thoracic; Arecoline; Atropine; Blotting, Western; Chemokines; Endothelia | 2013 |
Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline.
Topics: Areca; Arecoline; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cyclooxygenase 2; | 2003 |
The induction of prostaglandin E2 production, interleukin-6 production, cell cycle arrest, and cytotoxicity in primary oral keratinocytes and KB cancer cells by areca nut ingredients is differentially regulated by MEK/ERK activation.
Topics: Apoptosis; Areca; Arecoline; Blotting, Western; Cell Cycle; Cell Line, Tumor; Cell Survival; Cells, | 2004 |
Neurotransmitter-induced hypothalamic-pituitary-adrenal axis responsiveness is defective in inflammatory disease-susceptible Lewis rats: in vivo and in vitro studies suggesting globally defective hypothalamic secretion of corticotropin-releasing hormone.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Amphetamines; Animals; Arecoline; Corticosterone; Corti | 1992 |
Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats.
Topics: Animals; Arecoline; Carbachol; Carrageenan; Cerebellum; Corpus Striatum; Edema; Female; Foot; Gallam | 1991 |