arecoline has been researched along with Cell Transformation, Neoplastic in 11 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "First, the key gene related to oral cancer induced by Arecoline was screened." | 5.91 | MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma. ( Chang, A; Chen, H; Guo, X; Ling, J; Sun, Z; Zhao, H; Zhuo, X, 2023) |
| "Keratinocyte inflammation is crucial for the pathogenesis of cancer and tissue fibrosis." | 5.32 | Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. ( Chan, CP; Chang, MC; Chiang, BL; Hahn, LJ; Ho, YS; Jeng, JH; Lee, JJ; Lee, PH; Wang, TM; Wang, YJ, 2003) |
| "First, the key gene related to oral cancer induced by Arecoline was screened." | 1.91 | MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma. ( Chang, A; Chen, H; Guo, X; Ling, J; Sun, Z; Zhao, H; Zhuo, X, 2023) |
| "Oral squamous cell carcinoma (OSCC), one of the most deadliest malignancies in the world, is caused primarily by areca nut chewing in Southeast Asia." | 1.43 | Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline. ( Chang, YC; Chou, MY; Lee, SS; Peng, CY; Wang, TY; Yu, CC, 2016) |
| "Keratinocyte inflammation is crucial for the pathogenesis of cancer and tissue fibrosis." | 1.32 | Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline. ( Chan, CP; Chang, MC; Chiang, BL; Hahn, LJ; Ho, YS; Jeng, JH; Lee, JJ; Lee, PH; Wang, TM; Wang, YJ, 2003) |
| "Of these, 133 hamsters (80." | 1.31 | Cancer induction in the DMBA hamster cheek pouch: a modified technique using a promoter. ( Ahmed, A; Hengesteg, A; Robbins, KT; Wani, MK; Yarber, RH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, C | 3 |
| Kadigamuwa, C | 3 |
| Wu, S | 3 |
| Gao, Y | 3 |
| Chen, W | 3 |
| Gu, Y | 3 |
| Wang, S | 3 |
| Li, X | 3 |
| Sun, Z | 1 |
| Guo, X | 1 |
| Chen, H | 1 |
| Ling, J | 1 |
| Zhao, H | 1 |
| Chang, A | 1 |
| Zhuo, X | 1 |
| Islam, S | 1 |
| Uehara, O | 1 |
| Matsuoka, H | 1 |
| Kuramitsu, Y | 1 |
| Adhikari, BR | 1 |
| Hiraki, D | 1 |
| Toraya, S | 1 |
| Jayawardena, A | 1 |
| Saito, I | 1 |
| Muthumala, M | 1 |
| Nagayasu, H | 1 |
| Abiko, Y | 1 |
| Chiba, I | 1 |
| Lee, CH | 1 |
| Chang, JS | 1 |
| Syu, SH | 1 |
| Wong, TS | 1 |
| Chan, JY | 1 |
| Tang, YC | 1 |
| Yang, ZP | 1 |
| Yang, WC | 1 |
| Chen, CT | 1 |
| Lu, SC | 1 |
| Tang, PH | 1 |
| Yang, TC | 1 |
| Chu, PY | 1 |
| Hsiao, JR | 1 |
| Liu, KJ | 1 |
| Wang, TY | 1 |
| Peng, CY | 1 |
| Lee, SS | 1 |
| Chou, MY | 1 |
| Yu, CC | 1 |
| Chang, YC | 1 |
| Wang, YC | 1 |
| Tsai, YS | 1 |
| Huang, JL | 1 |
| Lee, KW | 1 |
| Kuo, CC | 1 |
| Wang, CS | 1 |
| Huang, AM | 1 |
| Chang, JY | 1 |
| Jong, YJ | 1 |
| Lin, CS | 1 |
| Jeng, JH | 1 |
| Wang, YJ | 1 |
| Chiang, BL | 1 |
| Lee, PH | 1 |
| Chan, CP | 1 |
| Ho, YS | 1 |
| Wang, TM | 1 |
| Lee, JJ | 1 |
| Hahn, LJ | 1 |
| Chang, MC | 1 |
| Gupta, PC | 1 |
| Wani, MK | 1 |
| Yarber, RH | 1 |
| Ahmed, A | 1 |
| Hengesteg, A | 1 |
| Robbins, KT | 1 |
| Ashby, J | 1 |
| Styles, JA | 1 |
| Boyland, E | 1 |
| Arjungi, KN | 1 |
1 review available for arecoline and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Areca nut: a review.
Topics: Alkaloids; Animals; Areca; Arecoline; Cell Transformation, Neoplastic; Habits; Humans; Indicators an | 1976 |
10 other studies available for arecoline and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma.
Topics: Areca; Arecoline; Biomarkers; Carcinoma; Cell Transformation, Neoplastic; Head and Neck Neoplasms; H | 2023 |
DNA hypermethylation of sirtuin 1 (SIRT1) caused by betel quid chewing-a possible predictive biomarker for malignant transformation.
Topics: Adult; Aged; Areca; Arecoline; Biomarkers; Carcinoma, Squamous Cell; Case-Control Studies; Cell Tran | 2020 |
IL-1β promotes malignant transformation and tumor aggressiveness in oral cancer.
Topics: Animals; Arecoline; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cells, Cultured; Gene | 2015 |
Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline.
Topics: 3' Untranslated Regions; Aldehyde Dehydrogenase 1 Family; Animals; Antineoplastic Agents; Arecoline; | 2016 |
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: implication for carcinogenesis.
Topics: Areca; Arecoline; Carcinogens; Cell Line, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; G | 2010 |
Roles of keratinocyte inflammation in oral cancer: regulating the prostaglandin E2, interleukin-6 and TNF-alpha production of oral epithelial cells by areca nut extract and arecoline.
Topics: Areca; Arecoline; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cyclooxygenase 2; | 2003 |
Areca nut use in India.
Topics: Alkaloids; Areca; Arecoline; Cell Transformation, Neoplastic; Habits; Humans; India; Mouth Neoplasms | 2007 |
Cancer induction in the DMBA hamster cheek pouch: a modified technique using a promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Arecoline; Carcinogens; Carcinoma, Squamous Cell; Cell Tr | 2001 |
Betel nuts, arecaidine, and oral cancer.
Topics: Animals; Areca; Arecoline; Carcinogens; Cell Transformation, Neoplastic; Chemical Phenomena; Chemist | 1979 |