arecoline has been researched along with Carcinoma, Hepatocellular in 3 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Arecoline is a well-known risk factor for oral submucosal fibrosis and cancer." | 1.72 | Arecoline promotes proliferation and migration of human HepG2 cells through activation of the PI3K/AKT/mTOR pathway. ( Chen, H; Dai, H; Jing, R; Liao, X; Pan, L; Xie, H; Xie, X, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Xie, H | 1 |
| Jing, R | 1 |
| Liao, X | 1 |
| Chen, H | 1 |
| Xie, X | 1 |
| Dai, H | 1 |
| Pan, L | 1 |
| Cheng, HL | 1 |
| Su, SJ | 1 |
| Huang, LW | 1 |
| Hsieh, BS | 1 |
| Hu, YC | 1 |
| Hung, TC | 1 |
| Chang, KL | 1 |
| Chao, HR | 1 |
| Wang, YF | 1 |
| Chen, HT | 1 |
| Ko, YC | 1 |
| Chang, EE | 1 |
| Huang, YJ | 1 |
| Tsai, FY | 1 |
| Tsai, CH | 1 |
| Wu, CH | 1 |
| Tsou, TC | 1 |
3 other studies available for arecoline and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Arecoline promotes proliferation and migration of human HepG2 cells through activation of the PI3K/AKT/mTOR pathway.
Topics: Arecoline; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Hep G2 Cells; Humans; Liver | 2022 |
Arecoline induces HA22T/VGH hepatoma cells to undergo anoikis - involvement of STAT3 and RhoA activation.
Topics: Animals; Anoikis; Antineoplastic Agents; Arecoline; Blotting, Western; Carcinoma, Hepatocellular; Ce | 2010 |
Differential effect of arecoline on the endogenous dioxin-responsive cytochrome P450 1A1 and on a stably transfected dioxin-responsive element-driven reporter in human hepatoma cells.
Topics: Arecoline; Biological Assay; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 CYP1A1; G | 2007 |