arecoline has been researched along with Carcinogenesis in 9 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "AEBN and arecoline induced dyslipidemia by downregulating AMPK (Thr-172) and activating ACC (Ser-79); they also downregulated tumor suppressor p53 (Ser-15)." | 7.91 | Treatment with the anti-diabetic drug metformin ameliorates betel-nut induced carcinogenesis in a murine model. ( Choudhury, Y; Laskar, J; Sengupta, M, 2019) |
| "AEBN and arecoline induced dyslipidemia by downregulating AMPK (Thr-172) and activating ACC (Ser-79); they also downregulated tumor suppressor p53 (Ser-15)." | 3.91 | Treatment with the anti-diabetic drug metformin ameliorates betel-nut induced carcinogenesis in a murine model. ( Choudhury, Y; Laskar, J; Sengupta, M, 2019) |
| "Oral carcinogenesis involves the progression of the normal mucosa into potentially malignant disorders and finally into cancer." | 1.56 | Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model. ( Chiang, WF; Hsieh, YP; Huang, LY; Huang, TT; Huang, WT; Hwang, DY; Jiang, SS; Liu, KJ; Wang, YY, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 6 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, C | 3 |
| Kadigamuwa, C | 3 |
| Wu, S | 3 |
| Gao, Y | 4 |
| Chen, W | 3 |
| Gu, Y | 4 |
| Wang, S | 3 |
| Li, X | 4 |
| Kong, D | 3 |
| Wang, G | 3 |
| Tang, Y | 3 |
| Guo, M | 3 |
| Ul Haq Khan, Z | 3 |
| Guo, Y | 3 |
| Gu, W | 3 |
| Ma, Y | 3 |
| Sui, M | 3 |
| Li, J | 3 |
| Yang, M | 3 |
| Ko, AM | 1 |
| Tu, HP | 1 |
| Ko, YC | 2 |
| Laskar, J | 1 |
| Sengupta, M | 1 |
| Choudhury, Y | 1 |
| Shiah, SG | 1 |
| Hsiao, JR | 1 |
| Chang, HJ | 1 |
| Hsu, YM | 1 |
| Wu, GH | 1 |
| Peng, HY | 1 |
| Chou, ST | 1 |
| Kuo, CC | 1 |
| Chang, JY | 1 |
| Huang, LY | 1 |
| Hsieh, YP | 1 |
| Wang, YY | 1 |
| Hwang, DY | 1 |
| Jiang, SS | 1 |
| Huang, WT | 1 |
| Chiang, WF | 1 |
| Liu, KJ | 1 |
| Huang, TT | 1 |
| Xie, X | 1 |
| Zhang, J | 1 |
| Song, J | 1 |
| Cheng, X | 1 |
| Ai, Y | 1 |
| Kuo, TM | 1 |
| Nithiyanantham, S | 1 |
| Lee, CP | 1 |
| Hsu, HT | 1 |
| Luo, SY | 1 |
| Lin, YZ | 1 |
| Yeh, KT | 1 |
| Wu, IC | 1 |
| Chen, YK | 1 |
| Wu, CC | 1 |
| Cheng, YJ | 1 |
| Chen, WC | 1 |
| Ko, HJ | 1 |
| Liu, YP | 1 |
| Chai, CY | 1 |
| Lin, HS | 1 |
| Wu, DC | 1 |
| Wu, MT | 1 |
1 review available for arecoline and Carcinogenesis
| Article | Year |
|---|---|
Systematic Review of Roles of Arecoline and Arecoline
Topics: Animals; Arecoline; Carcinogenesis; Carcinogens; Humans; Mice; MicroRNAs; Mouth Neoplasms | 2023 |
8 other studies available for arecoline and Carcinogenesis
| Article | Year |
|---|---|
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
RNA N6-Methyladenosine (m6A) Methyltransferase-like 3 Facilitates Tumorigenesis and Cisplatin Resistance of Arecoline-Exposed Oral Carcinoma.
Topics: Adenosine; Arecoline; Carcinogenesis; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cis | 2022 |
Potential health risk of areca nut consumption: Hazardous effect of toxic alkaloids and aflatoxins on human digestive system.
Topics: Adult; Aflatoxins; Alkaloids; Areca; Arecoline; Carcinogenesis; Child; Digestive System; Humans; Nut | 2022 |
Potential health risk of areca nut consumption: Hazardous effect of toxic alkaloids and aflatoxins on human digestive system.
Topics: Adult; Aflatoxins; Alkaloids; Areca; Arecoline; Carcinogenesis; Child; Digestive System; Humans; Nut | 2022 |
Potential health risk of areca nut consumption: Hazardous effect of toxic alkaloids and aflatoxins on human digestive system.
Topics: Adult; Aflatoxins; Alkaloids; Areca; Arecoline; Carcinogenesis; Child; Digestive System; Humans; Nut | 2022 |
Potential health risk of areca nut consumption: Hazardous effect of toxic alkaloids and aflatoxins on human digestive system.
Topics: Adult; Aflatoxins; Alkaloids; Areca; Arecoline; Carcinogenesis; Child; Digestive System; Humans; Nut | 2022 |
Treatment with the anti-diabetic drug metformin ameliorates betel-nut induced carcinogenesis in a murine model.
Topics: AMP-Activated Protein Kinases; Animals; Areca; Arecoline; Carcinogenesis; Disease Models, Animal; Dy | 2019 |
MiR-30a and miR-379 modulate retinoic acid pathway by targeting DNA methyltransferase 3B in oral cancer.
Topics: Alcohol Oxidoreductases; Aldehyde Dehydrogenase 1 Family; Arecoline; Carcinogenesis; Carcinoma, Squa | 2020 |
Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model.
Topics: 4-Nitroquinoline-1-oxide; Animals; Arecoline; Biomarkers, Tumor; Carcinogenesis; Carcinogens; Cell L | 2020 |
Fat mass and obesity-associated protein regulates tumorigenesis of arecoline-promoted human oral carcinoma.
Topics: Alpha-Ketoglutarate-Dependent Dioxygenase FTO; Areca; Arecoline; Carcinogenesis; Case-Control Studie | 2021 |
Arecoline N-oxide regulates oral squamous cell carcinoma development through NOTCH1 and FAT1 expressions.
Topics: Animals; Arecoline; Biomarkers, Tumor; Body Weight; Cadherins; Carcinogenesis; Carcinoma, Squamous C | 2019 |
Overexpression of ATPase Na+/+ transporting alpha 1 polypeptide, ATP1A1, correlates with clinical diagnosis and progression of esophageal squamous cell carcinoma.
Topics: Animals; Arecoline; Biomarkers, Tumor; Carcinogenesis; Carcinoma, Squamous Cell; Cell Line, Tumor; D | 2016 |