arecoline has been researched along with Cancer of Head in 9 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "First, the key gene related to oral cancer induced by Arecoline was screened." | 5.91 | MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma. ( Chang, A; Chen, H; Guo, X; Ling, J; Sun, Z; Zhao, H; Zhuo, X, 2023) |
| "The high prevalence of oral squamous cell carcinoma (OSCC) in South Asia is associated with habitual areca nut chewing." | 5.72 | Fat mass and obesity-associated protein regulates arecoline-exposed oral cancer immune response through programmed cell death-ligand 1. ( Ai, Y; Chen, W; Cheng, X; Gao, Y; Gu, Y; Li, X; Song, J; Zhang, J, 2022) |
| "First, the key gene related to oral cancer induced by Arecoline was screened." | 1.91 | MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma. ( Chang, A; Chen, H; Guo, X; Ling, J; Sun, Z; Zhao, H; Zhuo, X, 2023) |
| "The high prevalence of oral squamous cell carcinoma (OSCC) in South Asia is associated with habitual areca nut chewing." | 1.72 | Fat mass and obesity-associated protein regulates arecoline-exposed oral cancer immune response through programmed cell death-ligand 1. ( Ai, Y; Chen, W; Cheng, X; Gao, Y; Gu, Y; Li, X; Song, J; Zhang, J, 2022) |
| "Oral squamous cell carcinoma (OSCC), one of the most deadliest malignancies in the world, is caused primarily by areca nut chewing in Southeast Asia." | 1.43 | Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline. ( Chang, YC; Chou, MY; Lee, SS; Peng, CY; Wang, TY; Yu, CC, 2016) |
| "Oral squamous cell carcinoma (OSCC) is the sixth most prevalent malignancy worldwide and the third most common cancer in developing nation." | 1.42 | ZEB1 as an indicator of tumor recurrence for areca quid chewing-associated oral squamous cell carcinomas. ( Ho, CM; Hu, FW; Lee, SS; Lin, SS; Shieh, TM; Yu, CC; Yu, CH, 2015) |
| "Arecoline treatment dose dependently induced Lin28B expression in SG and FaDu cells." | 1.42 | Elevated Lin28B expression is correlated with lymph node metastasis in oral squamous cell carcinomas. ( Chou, MY; Lin, WT; Shieh, TM; Wang, TY; Yang, LC; Yu, CC, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 5 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Li, X | 1 |
| Chen, W | 1 |
| Gao, Y | 1 |
| Song, J | 1 |
| Gu, Y | 1 |
| Zhang, J | 2 |
| Cheng, X | 1 |
| Ai, Y | 1 |
| Xie, C | 1 |
| Li, Z | 2 |
| Hua, Y | 1 |
| Sun, S | 1 |
| Zhong, L | 1 |
| Chen, Q | 2 |
| Feng, H | 1 |
| Ji, N | 1 |
| Li, T | 1 |
| Zhou, X | 1 |
| Zeng, X | 1 |
| Tang, Z | 1 |
| Sun, C | 1 |
| Li, J | 1 |
| Fu, Y | 1 |
| Hu, Y | 1 |
| Zhu, Y | 1 |
| Hu, L | 1 |
| Shi, C | 1 |
| Zhang, Y | 1 |
| Zhou, S | 1 |
| Sun, Z | 1 |
| Guo, X | 1 |
| Chen, H | 1 |
| Ling, J | 1 |
| Zhao, H | 1 |
| Chang, A | 1 |
| Zhuo, X | 1 |
| Ko, HH | 1 |
| Peng, HH | 1 |
| Cheng, AN | 1 |
| Chou, HE | 1 |
| Hou, HH | 1 |
| Kuo, WT | 1 |
| Liu, WW | 1 |
| Kuo, MY | 1 |
| Lee, AY | 1 |
| Cheng, SJ | 1 |
| Yang, SH | 1 |
| Lee, TY | 1 |
| Ho, CA | 1 |
| Yang, CY | 1 |
| Huang, WY | 1 |
| Lin, YC | 1 |
| Nieh, S | 1 |
| Lin, YS | 1 |
| Chen, SF | 1 |
| Lin, FH | 1 |
| Ho, CM | 1 |
| Hu, FW | 1 |
| Lee, SS | 2 |
| Shieh, TM | 2 |
| Yu, CH | 1 |
| Lin, SS | 1 |
| Yu, CC | 3 |
| Lin, WT | 1 |
| Yang, LC | 1 |
| Wang, TY | 2 |
| Chou, MY | 2 |
| Peng, CY | 1 |
| Chang, YC | 1 |
9 other studies available for arecoline and Cancer of Head
| Article | Year |
|---|---|
Fat mass and obesity-associated protein regulates arecoline-exposed oral cancer immune response through programmed cell death-ligand 1.
Topics: Animals; Apoptosis; Areca; Arecoline; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Immunity; L | 2022 |
Identification of a BRAF/PA28γ/MEK1 signaling axis and its role in epithelial-mesenchymal transition in oral submucous fibrosis.
Topics: Arecoline; Autoantigens; Carcinoma, Squamous Cell; Epithelial-Mesenchymal Transition; Head and Neck | 2022 |
Low-dose arecoline regulates distinct core signaling pathways in oral submucous fibrosis and oral squamous cell carcinoma.
Topics: Arecoline; Carcinoma, Squamous Cell; Epigenesis, Genetic; Head and Neck Neoplasms; Humans; Mouth Muc | 2023 |
MYO1B as a prognostic biomarker and a therapeutic target in Arecoline-associated oral carcinoma.
Topics: Areca; Arecoline; Biomarkers; Carcinoma; Cell Transformation, Neoplastic; Head and Neck Neoplasms; H | 2023 |
Metastasis and immunosuppression promoted by mtDNA and PD-L1 in extracellular vesicles are reversed by WGP β-glucan in oral squamous cell carcinoma.
Topics: Arecoline; B7-H1 Antigen; beta-Glucans; Carcinoma, Squamous Cell; DNA, Mitochondrial; Extracellular | 2023 |
Exposure to nicotine-derived nitrosamine ketone and arecoline synergistically facilitates tumor aggressiveness via overexpression of epidermal growth factor receptor and its downstream signaling in head and neck squamous cell carcinoma.
Topics: Arecoline; Carcinoma, Squamous Cell; Cell Line, Tumor; ErbB Receptors; Gene Expression Regulation, E | 2018 |
ZEB1 as an indicator of tumor recurrence for areca quid chewing-associated oral squamous cell carcinomas.
Topics: Areca; Arecoline; Biomarkers, Tumor; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2015 |
Elevated Lin28B expression is correlated with lymph node metastasis in oral squamous cell carcinomas.
Topics: Adult; Aged; Arecoline; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement | 2015 |
Acquisition cancer stemness, mesenchymal transdifferentiation, and chemoresistance properties by chronic exposure of oral epithelial cells to arecoline.
Topics: 3' Untranslated Regions; Aldehyde Dehydrogenase 1 Family; Animals; Antineoplastic Agents; Arecoline; | 2016 |