arecoline has been researched along with Amentia in 2 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "25 mg-1 mg), arecoline (2 and 4 mg) and saline were administered intravenously over 30 minutes in a randomized double blind design to 11 patients with a clinical diagnosis of Alzheimer presenile dementia." | 9.05 | Physostigmine and arecoline: effects of intravenous infusions in Alzheimer presenile dementia. ( Christie, JE; Ferguson, J; Glen, AI; Shering, A, 1981) |
| "25 mg-1 mg), arecoline (2 and 4 mg) and saline were administered intravenously over 30 minutes in a randomized double blind design to 11 patients with a clinical diagnosis of Alzheimer presenile dementia." | 5.05 | Physostigmine and arecoline: effects of intravenous infusions in Alzheimer presenile dementia. ( Christie, JE; Ferguson, J; Glen, AI; Shering, A, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davies, P | 1 |
| Christie, JE | 1 |
| Shering, A | 1 |
| Ferguson, J | 1 |
| Glen, AI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| M2 Receptor Measurements in Aging and in Alzheimer's Disease[NCT00001917] | 150 participants | Observational | 1999-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for arecoline and Amentia
| Article | Year |
|---|---|
An update on the neurochemistry of Alzheimer disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Arecoline; Brain; Choline; Choline O-Acetyltransferase; Cho | 1983 |
1 trial available for arecoline and Amentia
| Article | Year |
|---|---|
Physostigmine and arecoline: effects of intravenous infusions in Alzheimer presenile dementia.
Topics: Alzheimer Disease; Arecoline; Clinical Trials as Topic; Dementia; Dose-Response Relationship, Drug; | 1981 |