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arecoline and Akinetic-Rigid Variant of Huntington Disease

arecoline has been researched along with Akinetic-Rigid Variant of Huntington Disease in 3 studies

Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.

Research Excerpts

ExcerptRelevanceReference
"Arecoline did produce significant alterations of blood pressure, heart rate, and body temperature, probably by central cholinergic stimulation."2.64Treatment of Huntington disease with a cholinergic agonist. ( Chase, TN; Nutt, JG; Rosin, A, 1978)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nutt, JG2
Durso, R1
Tamminga, CA1
Denaro, A1
Ruggeri, S1
Chase, TN2
Rosin, A1

Trials

1 trial available for arecoline and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Treatment of Huntington disease with a cholinergic agonist.
    Neurology, 1978, Volume: 28, Issue:10

    Topics: Adult; Arecoline; Clinical Trials as Topic; Female; Hemodynamics; Humans; Huntington Disease; Male;

1978

Other Studies

2 other studies available for arecoline and Akinetic-Rigid Variant of Huntington Disease

ArticleYear
Effect of cholinergic agents in Huntington's disease: a reappraisal.
    Neurology, 1983, Volume: 33, Issue:7

    Topics: Arecoline; Benztropine; Humans; Huntington Disease; Parasympatholytics; Parasympathomimetics; Physos

1983
Plasma growth hormone and prolactin response to dopaminergic GABAmimetic and cholinergic stimulation in Huntington's disease.
    Neurology, 1983, Volume: 33, Issue:9

    Topics: Adult; Apomorphine; Arecoline; Dopamine; Female; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hu

1983