arecoline has been researched along with Affective Psychosis, Bipolar in 4 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared central cholinergic responsiveness (using the latency to induction of rapid eye movement sleep after arecoline challenge as a response marker) in 90 subjects: patients with major depressive disorder (MDD) (n = 53), nonaffective psychiatric controls (n = 17), and normal controls (n = 20)." | 3.67 | Cholinergic REM sleep induction response correlation with endogenous major depressive subtype. ( Bell, J; Dube, S; Jackson, E; Jones, D; Kelwala, S; Sitaram, N, 1985) |
| " After several pilot dose-response studies, we administered 8 mg of the cholinergic agonist arecoline subcutaneously to eight pairs of normal volunteer identical twins and eight bipolar patients currently euthymic and unmedicated." | 1.27 | Behavioral, physiological, and neuroendocrine responses to arecoline in normal twins and "well state" bipolar patients. ( Gershon, ES; Gillin, JC; Jimerson, DC; Lawrence, D; Nadi, NS; Nurnberger, JI; Simmons-Alling, S; Sitaram, N; Tamminga, C, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nurnberger, JI | 2 |
| Jimerson, DC | 1 |
| Simmons-Alling, S | 1 |
| Tamminga, C | 1 |
| Nadi, NS | 1 |
| Lawrence, D | 1 |
| Sitaram, N | 3 |
| Gillin, JC | 2 |
| Gershon, ES | 3 |
| Nurnberger, J | 1 |
| Berrettini, W | 1 |
| Mendelson, W | 1 |
| Sack, D | 1 |
| Jones, D | 1 |
| Kelwala, S | 1 |
| Bell, J | 1 |
| Dube, S | 1 |
| Jackson, E | 1 |
4 other studies available for arecoline and Affective Psychosis, Bipolar
| Article | Year |
|---|---|
Behavioral, physiological, and neuroendocrine responses to arecoline in normal twins and "well state" bipolar patients.
Topics: Arecoline; Bipolar Disorder; Emotions; Female; Glycopyrrolate; Growth Hormone; Humans; Hydrocortison | 1983 |
Cholinergic regulation of mood and REM sleep: potential model and marker of vulnerability to affective disorder.
Topics: Acetylcholine; Adult; Arecoline; Bipolar Disorder; Depressive Disorder; Electroencephalography; Evok | 1982 |
Measuring cholinergic sensitivity: I. Arecoline effects in bipolar patients.
Topics: Adult; Arecoline; Bipolar Disorder; Brain; Female; Humans; Male; Middle Aged; Receptors, Cholinergic | 1989 |
Cholinergic REM sleep induction response correlation with endogenous major depressive subtype.
Topics: Adult; Aged; Arecoline; Bipolar Disorder; Brain; Depressive Disorder; Electroencephalography; Female | 1985 |