arecoline has been researched along with Abnormalities, Autosome in 6 studies
Arecoline: An alkaloid obtained from the betel nut (Areca catechu), fruit of a palm tree. It is an agonist at both muscarinic and nicotinic acetylcholine receptors. It is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. It has been used as a euphoriant in the Pacific Islands.
arecoline : A tetrahydropyridine that is 1,2,5,6-tetrahydropyridine with a methyl group at position 1, and a methoxycarbonyl group at position 3. An alkaloid found in the areca nut, it acts as an agonist of muscarinic acetylcholine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cells were fixed at 20 h and both chromosome aberrations (CAs) and sister chromatid exchanges (SCEs) were scored." | 1.30 | Influence of buthionine sulfoximine and reduced glutathione on arecoline-induced chromosomal damage and sister chromatid exchange in mouse bone marrow cells in vivo. ( Chatterjee, A; Deb, S, 1998) |
| "Arecoline was injected in doses of 0." | 1.26 | Chromosome-breaking ability of arecoline, a major betel-nut alkaloid, in mouse bone-marrow cells in vivo. ( Panigrahi, GB; Rao, AR, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Panigrahi, GB | 1 |
| Rao, AR | 1 |
| Stich, HF | 1 |
| Stich, W | 1 |
| Lam, PP | 1 |
| Trivedi, AH | 2 |
| Dave, BJ | 2 |
| Adhvaryu, SC | 1 |
| Deb, S | 2 |
| Chatterjee, A | 2 |
| Adhvaryu, SG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Cross-Cultural Adaptation of a Betel Quid Cessation Program and Evaluation of Its Effectiveness in a Malaysian High-Risk Community[NCT05782166] | 92 participants (Anticipated) | Interventional | 2024-01-02 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for arecoline and Abnormalities, Autosome
| Article | Year |
|---|---|
Chromosome-breaking ability of arecoline, a major betel-nut alkaloid, in mouse bone-marrow cells in vivo.
Topics: Animals; Areca; Arecoline; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Karyotyping; Meta | 1982 |
Potentiation of genotoxicity by concurrent application of compounds found in betel quid: arecoline, eugenol, quercetin, chlorogenic acid and Mn2+.
Topics: Animals; Areca; Arecoline; Cell Line; Chlorogenic Acid; Chromatids; Chromosome Aberrations; Cricetin | 1981 |
Genotoxic effects of nicotine in combination with arecoline on CHO cells.
Topics: Animals; Arecoline; CHO Cells; Chromosome Aberrations; Cricetinae; Dose-Response Relationship, Drug; | 1993 |
Influence of buthionine sulfoximine and reduced glutathione on arecoline-induced chromosomal damage and sister chromatid exchange in mouse bone marrow cells in vivo.
Topics: Animals; Arecoline; Bone Marrow Cells; Buthionine Sulfoximine; Chromosome Aberrations; Dose-Response | 1998 |
Genotoxic effect of arecoline given either by the peritoneal or oral route in murine bone marrow cells and the influence of N-acetylcysteine.
Topics: Acetylcysteine; Administration, Oral; Animals; Arecoline; Bone Marrow Cells; Cell Cycle; Chromosome | 1999 |
In vitro genotoxic effects of areca nut extract and arecoline.
Topics: Animals; Areca; Arecoline; CHO Cells; Chromosome Aberrations; Cricetinae; Dose-Response Relationship | 1992 |