Page last updated: 2024-08-24

arctigenin and Inflammation

arctigenin has been researched along with Inflammation in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (56.25)24.3611
2020's7 (43.75)2.80

Authors

AuthorsStudies
Fan, C; Feng, C; Li, H; Liu, M; Lu, H; Qi, Q; Su, H; Tang, W; Xiang, C; Xu, Y; Zhang, X; Zhou, Y1
Guo, R; Ji, Z; Li, H; Ma, Z1
Dong, X; Li, S; Lou, Z; Wang, D; Wang, G; Wu, Y; Yuan, Q; Zhou, X1
Huang, YS; Li, H; Li, Y; Lu, L; Ni, SH; Sun, SN; Wang, JJ; Wang, LJ; Xian, SX; Xiao, W; Yang, ZQ; Zhou, Z1
Huang, H; Liu, H; Shang, P; Tang, Q; Tang, S; Xu, J; Yang, S; Zhang, J; Zheng, X; Zhong, X; Zhou, W1
Deng, Y; Jiang, L; Li, W; Lu, Y1
Chen, F; Huang, Q; Jiang, H; Liu, J; Long, F; Lv, L; Qin, T; Ren, L; Xie, Y; Zeng, M1
Alaj, R; Beretta, G; Cavolli, R; Daci, A; Krasniqi, S; Neziri, B; Norata, GD1
Chen, JT; Chen, KY; Chen, YP; Ho, BY; Hsieh, MC; Hsu, AC; Hsu, RY; Lin, JA; Shen, TL; Tai, YT; Wang, GH; Wu, HT; Yao, HY1
Cheng, X; Cheng, Y; Da, Y; Li, Y; Wang, D; Wang, H; Wang, Y; Xue, Z; Yang, F; Yang, J; Yang, L; Zhang, L; Zhang, Q; Zhang, R; Zhou, D1
Ding, CG; Ding, XM; Dou, M; Han, F; Tian, PX; Wang, YX; Xia, XX; Xue, WJ; Zheng, J1
Dai, J; Dong, G; Fang, R; Li, C; Li, Z; Ma, Q; Ming, J; Ning, Z; Shi, H; Si, C; Xiong, H; Yan, F; Zhang, H; Zhang, J1
Bai, G; Cheng, BF; Dong, LY; Hou, YY; Jiang, M; Zhao, ZY1
Li, A; Pan, R; Wang, J; Wang, R; Zhang, X; Zhu, D1
Kim, CJ; Lee, JY1
Fan, T; Feng Zhang, Y; Jiang, WL; Zhu, J1

Other Studies

16 other study(ies) available for arctigenin and Inflammation

ArticleYear
Identification of phosphodiesterase-4 as the therapeutic target of arctigenin in alleviating psoriatic skin inflammation.
    Journal of advanced research, 2021, Volume: 33

    Topics: Animals; Cyclic Nucleotide Phosphodiesterases, Type 4; Furans; Humans; Inflammation; Leukocytes, Mononuclear; Lignans; Mice

2021
Arctigenin inhibits apoptosis, extracellular matrix degradation, and inflammation in human nucleus pulposus cells by up-regulating miR-483-3p.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:7

    Topics: Apoptosis; Cells, Cultured; Extracellular Matrix; Extracellular Matrix Proteins; Furans; Humans; Inflammation; Intervertebral Disc Degeneration; Lignans; MicroRNAs; NF-kappa B; Nucleus Pulposus

2022
Preventive effects of arctigenin from Arctium lappa L against LPS-induced neuroinflammation and cognitive impairments in mice.
    Metabolic brain disease, 2022, Volume: 37, Issue:6

    Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Arctium; Aspartic Acid Endopeptidases; Cognitive Dysfunction; Furans; Inflammation; Lignans; Lipopolysaccharides; Memory Disorders; Mice; Microglia; Neuroinflammatory Diseases; NF-kappa B; Toll-Like Receptor 4

2022
Arctigenin alleviates myocardial infarction injury through inhibition of the NFAT5-related inflammatory phenotype of cardiac macrophages/monocytes in mice.
    Laboratory investigation; a journal of technical methods and pathology, 2020, Volume: 100, Issue:4

    Topics: Animals; Furans; Heart; Inflammation; Lignans; Macrophages; Male; Mice; Mice, Inbred C57BL; Monocytes; Myocardial Infarction; Myocardium; RAW 264.7 Cells; Signal Transduction; Transcription Factors

2020
Arctigenin prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB axis: In vitro and in vivo studies.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:7

    Topics: Animals; Cartilage, Articular; Chondrocytes; Dinoprostone; Disease Models, Animal; Disease Progression; Furans; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Lignans; Mice; Molecular Docking Simulation; NF-kappa B; Nitric Oxide Synthase Type II; Nitrous Oxide; Osteoarthritis; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Signal Transduction

2020
Arctigenin suppresses fibroblast activity and extracellular matrix deposition in hypertrophic scarring by reducing inflammation and oxidative stress.
    Molecular medicine reports, 2020, Volume: 22, Issue:6

    Topics: Animals; Antioxidants; Bleomycin; Cicatrix, Hypertrophic; Cytokines; Disease Models, Animal; Extracellular Matrix; Female; Fibroblasts; Fibrosis; Furans; Inflammation; Lignans; Malondialdehyde; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Oxidative Stress; Pulmonary Fibrosis; Superoxide Dismutase; Transforming Growth Factor beta1

2020
Targeting Tristetraprolin Expression or Functional Activity Regulates Inflammatory Response Induced by MSU Crystals.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Anti-Inflammatory Agents; Autophagy; Caspase 1; Cell Culture Techniques; Cytokines; Furans; Inflammation; Lignans; Lysosomes; Mice; Mice, Inbred C57BL; Mitochondria; Protein Phosphatase 2; Reactive Oxygen Species; RNA, Small Interfering; Tristetraprolin; Uric Acid

2021
Arctigenin improves vascular tone and decreases inflammation in human saphenous vein.
    European journal of pharmacology, 2017, Sep-05, Volume: 810

    Topics: Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Furans; Humans; Inflammation; Inflammation Mediators; Lignans; Saphenous Vein; Vascular Resistance; Vasodilation

2017
Arctigenin protects against steatosis in WRL68 hepatocytes through activation of phosphoinositide 3-kinase/protein kinase B and AMP-activated protein kinase pathways.
    Nutrition research (New York, N.Y.), 2018, Volume: 52

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinases; Arctium; Carnitine O-Palmitoyltransferase; Fatty Liver; Furans; Hep G2 Cells; Hepatocytes; Humans; Inflammation; Intercellular Adhesion Molecule-1; Interleukins; Lignans; Liver; Non-alcoholic Fatty Liver Disease; Oleic Acid; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phytotherapy; Plant Extracts; PPAR alpha; Proto-Oncogene Proteins c-akt; Signal Transduction; Sterol Regulatory Element Binding Protein 1

2018
Arctigenin protects against liver injury from acute hepatitis by suppressing immune cells in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: Acute Disease; Animals; CD4-Positive T-Lymphocytes; Concanavalin A; Furans; Hepatitis; Inflammation; Inflammation Mediators; Interleukin-10; Lignans; Liver; Macrophages; Male; Mice; Mice, Inbred BALB C; Natural Killer T-Cells; Protective Agents; RAW 264.7 Cells

2018
Arctigenin: A two-edged sword in ischemia/reperfusion induced acute kidney injury.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 103

    Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Furans; Inflammation; Kidney; Lignans; Male; Mice, Inbred C57BL; Oxidative Stress; Reperfusion Injury

2018
Arctigenin Ameliorates Inflammation by Regulating Accumulation and Functional Activity of MDSCs in Endotoxin Shock.
    Inflammation, 2018, Volume: 41, Issue:6

    Topics: Animals; Arginase; Furans; Inflammation; Interferon Regulatory Factors; Lignans; Lipopolysaccharides; Mice; MicroRNAs; Myeloid-Derived Suppressor Cells; Nitric Oxide Synthase Type II; RNA, Messenger; Shock, Septic

2018
[Anti-inflammatory mechanism of qingfei xiaoyan wan studied with network pharmacology].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Asthma; Cell Line; Cholic Acid; Coumaric Acids; Cytokines; Drug Combinations; Drugs, Chinese Herbal; Epithelial Cells; Female; Furans; Guinea Pigs; Humans; Inflammation; Lignans; Lung; Male; MAP Kinase Signaling System; Random Allocation; Receptors, IgE; Toll-Like Receptors

2013
Arctigenin suppresses transforming growth factor-β1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen species-dependent ERK/NF-κB signaling pathway in renal tubular epithe
    Free radical research, 2015, Volume: 49, Issue:9

    Topics: Antigens, CD; Antioxidants; Cadherins; Cell Movement; Chemokine CCL2; Epithelial Cells; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Furans; Gene Expression Regulation; Humans; Inflammation; Kidney Tubules; Lignans; Membrane Glycoproteins; Microscopy, Fluorescence; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta1; Zonula Occludens-1 Protein

2015
Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits type I-IV allergic inflammation and pro-inflammatory enzymes.
    Archives of pharmacal research, 2010, Volume: 33, Issue:6

    Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; B-Lymphocytes; Enzyme Inhibitors; Furans; Guinea Pigs; Hemagglutination; Histamine Antagonists; Histamine Release; Hypersensitivity; Inflammation; Lignans; Lung; Male; Mast Cells; Mice; Mice, Inbred BALB C; Rats; Rats, Sprague-Dawley; Skin; T-Lymphocytes

2010
Arctigenin protects focal cerebral ischemia-reperfusion rats through inhibiting neuroinflammation.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Arctium; Furans; Infarction, Middle Cerebral Artery; Inflammation; Interleukin-1beta; Lignans; Macrophages; Male; Microglia; Neuroprotective Agents; Phytotherapy; Rats; Rats, Sprague-Dawley; Seeds; Tumor Necrosis Factor-alpha

2012