Compounds > arctigenin
Page last updated: 2024-08-24

arctigenin and Colitis

arctigenin has been researched along with Colitis in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Dai, Y; Fang, YL; Lv, CJ; Qiao, SM; Tao, Y; Wei, ZF; Xia, YF; Yue, MF; Yun, XM1
Bian, D; Dai, Y; Dou, Y; Kong, L; Tong, B; Wei, Z; Wu, X; Xia, Y; Yang, Y; Ye, J1
Bian, D; Dai, Y; Dou, Y; Luo, J; Tong, B; Wu, X; Xia, Y; Yang, Y1
Dai, Y; Luo, J; Tong, B; Wei, Z; Wu, X; Xia, Y; Yang, Y; Yuan, X; Yue, M1
Gu, W; Han, MJ; Hyam, SR; Jang, SE; Jeong, JJ; Kim, DH; Kim, KA; Lee, IA1

Other Studies

5 other study(ies) available for arctigenin and Colitis

ArticleYear
Phytoestrogen arctigenin preserves the mucus barrier in inflammatory bowel diseases by inhibiting goblet cell apoptosis via the ERβ/TRIM21/PHB1 pathway.
    Phytotherapy research : PTR, 2022, Volume: 36, Issue:8

    Topics: Animals; Apoptosis; Colitis; Estrogen Receptor beta; Furans; Goblet Cells; Inflammatory Bowel Diseases; Lignans; Mice; Mice, Inbred C57BL; Mucus; Phytoestrogens; Prohibitins

2022
Arctigenin but not arctiin acts as the major effective constituent of Arctium lappa L. fruit for attenuating colonic inflammatory response induced by dextran sulfate sodium in mice.
    International immunopharmacology, 2014, Volume: 23, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arctium; Colitis; Dextran Sulfate; Dose-Response Relationship, Drug; Fruit; Furans; Glucosides; Lignans; Male; Mesalamine; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Molecular Structure; NF-kappa B; Oxidative Stress; Plant Extracts

2014
Arctigenin exerts anti-colitis efficacy through inhibiting the differentiation of Th1 and Th17 cells via an mTORC1-dependent pathway.
    Biochemical pharmacology, 2015, Aug-15, Volume: 96, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cell Differentiation; Colitis; Dextran Sulfate; Furans; Humans; Jurkat Cells; Lignans; Male; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Multiprotein Complexes; Signal Transduction; Th1 Cells; Th17 Cells; TOR Serine-Threonine Kinases

2015
Arctigenin functions as a selective agonist of estrogen receptor β to restrict mTORC1 activation and consequent Th17 differentiation.
    Oncotarget, 2016, Dec-20, Volume: 7, Issue:51

    Topics: Animals; Cell Differentiation; Colitis; Dextran Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Estrogen Receptor Antagonists; Estrogen Receptor beta; Female; Furans; HSP90 Heat-Shock Proteins; Humans; Jurkat Cells; Lignans; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Ovariectomy; Phosphorylation; Regulatory-Associated Protein of mTOR; Selective Estrogen Receptor Modulators; Signal Transduction; Th17 Cells; Time Factors; Transcription, Genetic

2016
Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K/AKT pathway and polarizing M1 macrophages to M2-like macrophages.
    European journal of pharmacology, 2013, May-15, Volume: 708, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Colitis; Cytokines; Furans; Lignans; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Peroxidase; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Trinitrobenzenesulfonic Acid

2013