Page last updated: 2024-08-24

arctigenin and Cancer of Pancreas

arctigenin has been researched along with Cancer of Pancreas in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (27.27)29.6817
2010's12 (54.55)24.3611
2020's4 (18.18)2.80

Authors

AuthorsStudies
Awale, S; Esumi, H; Kadota, S; Tezuka, Y; Win, NN3
Awale, S; Esumi, H; Kadota, S; Li, F; Onozuka, H; Tezuka, Y1
Awale, S; Esumi, H; Kadota, S; Li, F; Tezuka, Y; Zhang, H1
Abdelhamed, S; Athikomkulchai, S; Awale, S; Miyatake, R; Saiki, I; Ueda, JY; Yokoyama, S1
Abdelhamed, S; Athikomkulchai, S; Awale, S; Dibwe, DF; Miyatake, R; Saiki, I; Ueda, JY; Yokoyama, S1
Awale, S; Shakya, B; Ueda, JY; Yadav, PN1
Adachi, I; Chiba, S; Esumi, H; Kaji, S; Kato, A; Kurashima, Y; Minehira, D; Ogura, T; Okada, T; Takada, M; Toyooka, N; Urata, H1
Awale, S; Do, TN; Esumi, H; Le, TH; Nguyen, HX; Nguyen, MT; Nguyen, NT1
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Li, J; Mudogo, V; Seupel, R1
Awale, S; Balachandran, C; Dibwe, DF; Phrutivorapongkul, A; Sun, S1
Cui, W; Li, JX; Liu, CX; Shen, Q; Wang, J; Wang, Y; Wu, J; Zhang, L; Zhang, YC1
Awale, S; Bringmann, G; Bruhn, T; Brun, R; Feineis, D; Kaiser, M; Mudogo, V; Schmidt, D; Tshitenge, DT; Würthner, F1
Awale, S; Dibwe, DF; El-Mekkawy, S; Kohyama, A; Matsuya, Y; Meselhy, MR; Yokoyama, R1
Awale, S; Dibwe, DF; Kim, MJ; Omar, AM; Sun, S; Tawila, AM; Toyooka, N; Ueda, JY1
Awale, S; Chaithatwatthana, K; Dibwe, DF; Fujino, H; Kim, MJ; Omar, AM; Phan, ND; Phrutivorapongkul, A; Pongterdsak, N; Sun, S1
Awale, S; Dibwe, DF; Fujii, T; Kalauni, SK; Maneenet, J; Omar, AM; Phan, ND; Sato, M; Sun, S; Toyooka, N1
Gao, Q; Yang, M; Zuo, Z1
Esumi, H; Fujioka, R; Ikeda, M; Kishino, S; Mochizuki, N; Nomura, S; Owada, S; Sato, A; Tsuchihara, K; Yomoda, S1
Saif, MW; Strimpakos, AS1
Awale, S; Esumi, H; Kadota, S; Kalauni, SK; Kurashima, Y; Lu, J; Tezuka, Y1

Reviews

1 review(s) available for arctigenin and Cancer of Pancreas

ArticleYear
Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L.
    Acta pharmacologica Sinica, 2018, Volume: 39, Issue:5

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arctium; Cell Line, Tumor; Diabetic Nephropathies; Furans; Glucosides; Humans; Lignans; Neuroprotective Agents; Pancreatic Neoplasms

2018

Trials

1 trial(s) available for arctigenin and Cancer of Pancreas

ArticleYear
Change in plasma lactate concentration during arctigenin administration in a phase I clinical trial in patients with gemcitabine-refractory pancreatic cancer.
    PloS one, 2018, Volume: 13, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Arctium; Area Under Curve; Biomarkers; Carcinoma, Adenosquamous; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Furans; Gemcitabine; Gluconeogenesis; Humans; Kaplan-Meier Estimate; Kidney; Lactic Acid; Lignans; Liver; Mitochondria; Oxidative Phosphorylation; Pancreatic Neoplasms; Plant Extracts

2018

Other Studies

20 other study(ies) available for arctigenin and Cancer of Pancreas

ArticleYear
Bioactive secondary metabolites from Boesenbergia pandurata of Myanmar and their preferential cytotoxicity against human pancreatic cancer PANC-1 cell line in nutrient-deprived medium.
    Journal of natural products, 2007, Volume: 70, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chalcones; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Myanmar; Pancreatic Neoplasms; Plants, Medicinal; Rhizome; Terpenes; Zingiberaceae

2007
Constituents of Brazilian red propolis and their preferential cytotoxic activity against human pancreatic PANC-1 cancer cell line in nutrient-deprived condition.
    Bioorganic & medicinal chemistry, 2008, Jan-01, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Necrosis; Nutritional Requirements; Pancreatic Neoplasms; Phytotherapy; Plant Extracts; Propolis; Sensitivity and Specificity

2008
Novel anticancer agents, kayeassamins A and B from the flower of Kayea assamica of Myanmar.
    Bioorganic & medicinal chemistry letters, 2008, Aug-15, Volume: 18, Issue:16

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Clusiaceae; Coumarins; Drug Design; Drug Screening Assays, Antitumor; Flowers; Humans; Magnetic Resonance Spectroscopy; Models, Chemical; Monoterpenes; Myanmar; Pancreatic Neoplasms; Plant Extracts

2008
Novel anticancer agents, kayeassamins C-I from the flower of Kayea assamica of Myanmar.
    Bioorganic & medicinal chemistry, 2008, Sep-15, Volume: 16, Issue:18

    Topics: Antineoplastic Agents, Phytogenic; Biological Assay; Cell Line, Tumor; Coumarins; Humans; Myanmar; Pancreatic Neoplasms; Plant Extracts; Plants, Medicinal; Structure-Activity Relationship; Time Factors; Toxicity Tests

2008
Chemical constituents of propolis from Myanmar and their preferential cytotoxicity against a human pancreatic cancer cell line.
    Journal of natural products, 2009, Volume: 72, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Myanmar; Pancreatic Neoplasms; Propolis; Stereoisomerism; Triterpenes

2009
Antiausterity agents from Uvaria dac and their preferential cytotoxic activity against human pancreatic cancer cell lines in a nutrient-deprived condition.
    Journal of natural products, 2012, Jun-22, Volume: 75, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Crystallography, X-Ray; Cyclohexenes; Drug Screening Assays, Antitumor; Humans; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Thailand; Uvaria

2012
Uvaridacols E-H, highly oxygenated antiausterity agents from Uvaria dac.
    Journal of natural products, 2012, Nov-26, Volume: 75, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Cyclohexenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Plant Stems; Thailand; Uvaria

2012
Discovery of 2-pyridineformamide thiosemicarbazones as potent antiausterity agents.
    Bioorganic & medicinal chemistry letters, 2014, Jan-15, Volume: 24, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Formamides; Humans; Pancreatic Neoplasms; Pyridines; Thiosemicarbazones

2014
Synthesis of new tricyclic thiolactams as potent antitumor agent for pancreatic cancer.
    Bioorganic & medicinal chemistry letters, 2016, 06-01, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lactams; Mice; Molecular Structure; Neoplasms, Experimental; Pancreatic Neoplasms; Structure-Activity Relationship; Sulfhydryl Compounds

2016
Chemical Constituents of Mangifera indica and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line.
    Journal of natural products, 2016, 08-26, Volume: 79, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Mangifera; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Plant Bark; Triterpenes; Vietnam

2016
Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line.
    Journal of natural products, 2017, 10-27, Volume: 80, Issue:10

    Topics: Algorithms; Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Congo; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Isoquinolines; Leishmania donovani; Magnoliopsida; Molecular Structure; Naphthalenes; Nuclear Magnetic Resonance, Biomolecular; Pancreatic Neoplasms; Plasmodium falciparum; Rats; Trypanosoma brucei rhodesiense; Trypanosoma cruzi; Tumor Cells, Cultured

2017
Chemical Constituents of Thai Citrus hystrix and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line.
    Journal of natural products, 2018, 08-24, Volume: 81, Issue:8

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Size; Citrus; Coumarins; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Organelles; Pancreatic Neoplasms; Thailand; Tumor Microenvironment; Tumor Stem Cell Assay; Wound Healing

2018
Synthesis and evaluation of tetrahydroquinolin-2(1H)-one derivatives as novel anti-pancreatic cancer agents via targeting autophagy.
    European journal of medicinal chemistry, 2019, May-15, Volume: 170

    Topics: Animals; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Male; Mice, Nude; Pancreas; Pancreatic Neoplasms; Quinolines

2019
Ealamines A-H, a Series of Naphthylisoquinolines with the Rare 7,8'-Coupling Site, from the Congolese Liana
    Journal of natural products, 2019, 11-22, Volume: 82, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antiprotozoal Agents; Caryophyllales; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Leishmania; Molecular Structure; Naphthalenes; Pancreatic Neoplasms; Plant Components, Aerial; Plant Leaves; Plasmodium; Rats; Trypanosoma

2019
Synthesis of guggulsterone derivatives as potential anti-austerity agents against PANC-1 human pancreatic cancer cells.
    Bioorganic & medicinal chemistry letters, 2020, 04-01, Volume: 30, Issue:7

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pancreatic Neoplasms; Pregnenediones; Structure-Activity Relationship

2020
Chemical constituents of Callistemon citrinus from Egypt and their antiausterity activity against PANC-1 human pancreatic cancer cell line.
    Bioorganic & medicinal chemistry letters, 2020, 08-15, Volume: 30, Issue:16

    Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Egypt; Humans; Molecular Structure; Myrtaceae; Pancreatic Neoplasms; Structure-Activity Relationship; Terpenes; Tumor Microenvironment

2020
A new anti-austerity agent, 4'-O-methylgrynullarin from Derris scandens induces PANC-1 human pancreatic cancer cell death under nutrition starvation via inhibition of Akt/mTOR pathway.
    Bioorganic & medicinal chemistry letters, 2021, 05-15, Volume: 40

    Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Line, Tumor; Cell Movement; Derris; Drug Screening Assays, Antitumor; Flowers; Hemiterpenes; Humans; Isoflavones; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases

2021
Abietane diterpenes from Abies spectabilis and their anti-pancreatic cancer activity against the MIA PaCa-2 cell line.
    Bioorganic & medicinal chemistry letters, 2022, 06-15, Volume: 66

    Topics: Abies; Abietanes; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pancreatic Neoplasms; Plant Extracts

2022
Update on phase I studies in advanced pancreatic adenocarcinoma. Hunting in darkness?
    JOP : Journal of the pancreas, 2013, Jul-10, Volume: 14, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials, Phase I as Topic; Deoxycytidine; Furans; Gemcitabine; Humans; Hyaluronoglucosaminidase; Lignans; Mutation; Pancreatic Neoplasms; Polyethylene Glycols; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Recombinant Proteins; RNA Interference; Treatment Outcome

2013
Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation.
    Cancer research, 2006, Feb-01, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Arctium; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Furans; Glucose; Humans; Lignans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Xenograft Model Antitumor Assays

2006