arabinofuranosyluracil and Neoplasms

arabinofuranosyluracil has been researched along with Neoplasms in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's2 (11.11)18.2507
2000's9 (50.00)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alauddin, MM1
Douglas, KA; Kim, S; Lawhorn-Crews, JM; Li, J; LoRusso, PM; Mangner, TJ; McHugh, CI; Shields, AF; Wu, J1
Collins, JM; Douglas, KA; Jones, SK; Lawhorn-Crews, JM; Mangner, TJ; McHugh, CI; Modi, D; Shields, AF1
Chen, Q; Deng, X; He, F; Huang, Y; Li, GC; Ling, CC; Liu, Y; Minami, A; Sun, X; Wen, B; Xing, L; Zanzonico, PB1
Emerick, LE; Krohn, KA; Plotnik, DA; Schwartz, JL; Unadkat, JD1
Grierson, JR; Jordan, R; Krohn, KA; Schwartz, JL; Tamura, Y1
Collins, JM; Douglas, K; Mangner, TJ; Muzik, O; Shields, AF; Sloan, A; Sun, H; Vaishampayan, U1
Deng, WP; Gelovani, JG; Hwang, JJ; Lin, M; Liu, RS; Wang, HE; Wei, HJ; Yu, HM1
Douglas, KA; Lawhorn-Crews, JM; Shields, AF; Tehrani, OS1
Knaus, EE; Lee, YW; Mercer, JR; Wiebe, LI1
Kato, A; Ogura, K; Okuda, H; Takubo, H; Watabe, T1
Collins, JM; Katki, AG; Klecker, RW1
Cheng, YC1
Akhurst, T; Balatoni, J; Bennett, JJ; Blasberg, R; Doubrovin, M; Federoff, H; Finn, R; Fong, Y; Hackman, T; Johnson, P; Larson, SM; Malholtra, S; Tjuvajev, J1
Bermudes, D; Blasberg, R; King, I; Luo, X; Tjuvajev, J; Zheng, LM1
Hill, DL; Nan, L; Oliver, P; Rhie, JK; Wang, H; Wang, S; Wang, Z; Zhang, R1
Abbruzzese, JL; Castellanos, AM; Krakoff, IH; Legha, SS; Levy, JK; Raber, MN; Schmidt, S1
Burchenal, JH; Fanucchi, MP; Fox, JJ; Leyland-Jones, B; Watanabe, KA; Young, CW1

Reviews

1 review(s) available for arabinofuranosyluracil and Neoplasms

ArticleYear
Journey of 2'-deoxy-2'-fluoro-5-methyl-1-β-D-arabinofuranosyluracil (FMAU): from Antiviral Drug to PET Imaging Agent.
    Current medicinal chemistry, 2018, Volume: 25, Issue:16

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Carbon Radioisotopes; Contrast Media; Fluorine Radioisotopes; Humans; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals

2018

Trials

2 trial(s) available for arabinofuranosyluracil and Neoplasms

ArticleYear
Integrating Dynamic Positron Emission Tomography and Conventional Pharmacokinetic Studies to Delineate Plasma and Tumor Pharmacokinetics of FAU, a Prodrug Bioactivated by Thymidylate Synthase.
    Journal of clinical pharmacology, 2016, Volume: 56, Issue:11

    Topics: Arabinofuranosyluracil; Humans; Infusions, Intravenous; Neoplasms; Positron-Emission Tomography; Prodrugs; Thymidylate Synthase

2016
Imaging DNA synthesis with [18F]FMAU and positron emission tomography in patients with cancer.
    European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:1

    Topics: Adult; Aged; Arabinofuranosyluracil; Biomarkers, Tumor; DNA, Neoplasm; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Organ Specificity; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution

2005

Other Studies

15 other study(ies) available for arabinofuranosyluracil and Neoplasms

ArticleYear
Effects of capecitabine treatment on the uptake of thymidine analogs using exploratory PET imaging agents:
    Cancer imaging : the official publication of the International Cancer Imaging Society, 2016, Oct-17, Volume: 16, Issue:1

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Arabinofuranosyluracil; Capecitabine; Dideoxynucleosides; Female; Humans; Male; Middle Aged; Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals

2016
Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers.
    Cancer research, 2008, Oct-15, Volume: 68, Issue:20

    Topics: Animals; Antigens, Neoplasm; Arabinofuranosyluracil; Autoradiography; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Hypoxia; Etanidazole; Female; Gene Expression; Green Fluorescent Proteins; Herpesvirus 1, Human; HT29 Cells; Humans; Hydrocarbons, Fluorinated; Immunohistochemistry; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Nitroimidazoles; Positron-Emission Tomography; Thymidine Kinase; Tissue Distribution; Transplantation, Heterologous

2008
Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2010, Volume: 51, Issue:9

    Topics: Arabinofuranosyluracil; Biological Transport; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Equilibrative Nucleoside Transport Proteins; Humans; Kinetics; Neoplasms; Positron-Emission Tomography; Thymidine; Tritium

2010
Monitoring tumor cell proliferation by targeting DNA synthetic processes with thymidine and thymidine analogs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:12

    Topics: Animals; Arabinofuranosyluracil; Cell Division; Cell Line, Tumor; Dideoxynucleosides; DNA; Drug Delivery Systems; Humans; Metabolic Clearance Rate; Mice; Neoplasm Staging; Neoplasms; Radiopharmaceuticals; Thymidine; Thymidine Kinase; Tomography, Emission-Computed; Tritium

2003
Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2006, Volume: 47, Issue:7

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Line, Tumor; Female; Floxuridine; Fluorodeoxyglucose F18; Ganciclovir; Genetic Therapy; Herpesvirus 1, Human; Humans; Iodine Radioisotopes; Mice; Neoplasms; Prodrugs; Thymidine Kinase; Tyrosine

2006
Tracking cellular stress with labeled FMAU reflects changes in mitochondrial TK2.
    European journal of nuclear medicine and molecular imaging, 2008, Volume: 35, Issue:8

    Topics: Arabinofuranosyluracil; Cell Line, Tumor; Humans; Mitochondria; Neoplasms; Oxidative Stress; Radionuclide Imaging; Radiopharmaceuticals; Thymidine Kinase; Tritium

2008
The synthesis of [36Cl]-, [82Br]- and [123I]-labelled 1-(3'-chloro-(bromo and iodo)-3'-deoxy-beta-D-arabinofuranosyl)uracil.
    The International journal of applied radiation and isotopes, 1984, Volume: 35, Issue:11

    Topics: Arabinofuranosyluracil; Bromine; Chlorine; Humans; Iodine Radioisotopes; Isotope Labeling; Neoplasms; Radioisotopes; Radionuclide Imaging; Uridine

1984
A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Arabinofuranosyluracil; Bromouracil; Cause of Death; Dihydrouracil Dehydrogenase (NADP); Drug Interactions; Fluorouracil; Half-Life; Herpes Zoster; Humans; Liver; Neoplasms; Oxidoreductases; Prodrugs; Rats; Tissue Distribution

1998
Suicide prodrugs activated by thymidylate synthase: rationale for treatment and noninvasive imaging of tumors with deoxyuridine analogues.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:8

    Topics: Animals; Arabinofuranosyluracil; Cell Division; DNA; Floxuridine; Fluorine Radioisotopes; Humans; Methylation; Mice; Neoplasms; Phosphorylation; Prodrugs; Thymidylate Synthase; Tumor Cells, Cultured

1999
Potential use of antiviral L(-)nucleoside analogues for the prevention or treatment of viral associated cancers.
    Cancer letters, 2001, Volume: 162 Suppl

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Dioxolanes; Hepatitis B virus; Herpesvirus 4, Human; Humans; Neoplasms; Nucleosides; Stereoisomerism; Structure-Activity Relationship; Uracil; Virus Diseases; Zalcitabine

2001
Positron emission tomography imaging for herpes virus infection: Implications for oncolytic viral treatments of cancer.
    Nature medicine, 2001, Volume: 7, Issue:7

    Topics: Antiviral Agents; Arabinofuranosyluracil; Autoradiography; Biological Therapy; Herpesvirus 1, Human; Humans; Neoplasms; Promoter Regions, Genetic; Thymidine Kinase; Tomography, Emission-Computed; Tumor Cells, Cultured; Virus Replication

2001
Salmonella-based tumor-targeted cancer therapy: tumor amplified protein expression therapy (TAPET) for diagnostic imaging.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, Jul-06, Volume: 74, Issue:1-3

    Topics: Animals; Arabinofuranosyluracil; Genetic Markers; Genetic Vectors; Herpesvirus 1, Human; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms; Protein-Tyrosine Kinases; Salmonella; Tissue Distribution; Tumor Cells, Cultured

2001
Radiolabeled 2'-fluorodeoxyuracil-beta-D-arabinofuranoside (FAU) and 2'-fluoro-5-methyldeoxyuracil-beta -D-arabinofuranoside (FMAU) as tumor-imaging agents in mice.
    Cancer chemotherapy and pharmacology, 2002, Volume: 49, Issue:5

    Topics: Animals; Arabinofuranosyluracil; DNA, Neoplasm; Humans; Mice; Mice, SCID; Muscle, Skeletal; Neoplasm Transplantation; Neoplasms; Radiopharmaceuticals; Spleen; Thymidine; Tissue Distribution; Tomography, Emission-Computed; Transplantation, Heterologous

2002
Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity.
    Investigational new drugs, 1989, Volume: 7, Issue:2-3

    Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Colonic Neoplasms; Drug Evaluation; Electroencephalography; Female; Fibrosarcoma; Hematologic Diseases; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasms; Nervous System Diseases; Nervous System Neoplasms

1989
Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU).
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Central Nervous System Diseases; Drug Evaluation; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Platelet Count; Uridine; Vomiting

1985