arabinofuranosyluracil and Hepatitis B Virus Infection

arabinofuranosyluracil has been researched along with Hepatitis B Virus Infection in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's19 (63.33)18.2507
2000's7 (23.33)29.6817
2010's4 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cho, JY; Kim, NH; Koh, MS; Lee, JH; Park, KS; Park, SH1
Kim, HS; Park, SA; Shin, YI; Yang, CY1
Shouval, D1
Byun, KS; Cho, M; Cho, SH; Chon, CY; Chung, YH; Han, BH; Han, CJ; Han, JY; Hwang, JS; Hwang, SG; Kim, BI; Kim, HC; Kim, JH; Kim, TH; Kim, YS; Koh, KC; Lee, HJ; Lee, HS; Lee, KS; Lee, MS; Lee, YS; Paik, SW; Ryu, SH; Um, SH; Yang, JM; Yoo, BC; Yoo, HW; Yoo, K1
Abdelhamed, AM; Furman, PA; Isom, HC; Kelley, CM; Miller, TG1
Chevallier, M; Guerret, S; Jacquard, AC; Jamard, C; Nassal, M; Peyrol, S; Pichoud, C; Ren, S; Rimsky, LT; Schultz, U; Trepo, C; Werle, B; Zoulim, F1
Buti, M; Esteban, R1
Kang, MJ; Kim, DH; Lee, HS; Lee, J; Yoo, BC; Yoo, HH; Yoo, HW1
Byun, KS; Cho, M; Cho, SH; Choi, JY; Choi, SK; Chon, CY; Chung, YH; Han, BH; Han, JY; Hwang, JS; Hwang, SG; Jeong, SH; Kim, BI; Kim, DG; Kim, HC; Kim, JH; Kim, TH; Kim, YS; Kweon, YO; Lee, HJ; Lee, HS; Lee, HY; Lee, KS; Lee, MS; Lee, YJ; Lee, YS; Paik, SW; Park, JW; Ryu, SH; Um, SH; Yang, JM; Yoo, BC; Yoo, HW; Yoo, K1
Conjeevaram, H; Di Bisceglie, AM; Fried, MW; Kleiner, D; Luciano, C; McKenzie, R; Park, Y; Sallie, R; Savarese, B; Tsokos, M1
Swartz, MN1
de Man, RA; Heijtink, RA; Niesters, HG; Schalm, SW2
Caldwell, SH; Dickson, RC; Ishitani, MB; McGory, RW; Oliveira, WM; Pruett, TL; Stevenson, WC1
Caldwell, S; Dickson, R; Gaffey, M; Ishitani, M; Lobo, P; McCullough, C; Pruett, T; Stevenson, W1
Brahams, D1
Marwick, C1
Marshall, E1
Macilwain, C1
Bari, A1
Lewis, W; Perrino, FW1
Gordon, M1
Colacino, JM1
Ascenzi, MA; de Courten-Myers, G; Engelman, L; Gerin, JL; Griniuviene, B; Hornbuckle, WE; Levine, ES; Lewis, W; Montione, R; Tankersley, KO; Tennant, BC1
Gaffey, MJ; Hoofnagle, JH; Kleiner, DE; McKenzie, R; Nichols, L; Sallie, R; Straus, SE; Tsokos, M1
de Man, RA; Honkoop, P; Schalm, SW; Scholte, HR1
Ascenzi, MA; Baldwin, BH; Bowsher, RR; Colacino, JM; Cote, PJ; Engelhardt, JA; Erb, HN; Gerin, JL; Graham, LA; Hornbuckle, WE; Korba, BE; Lewis, W; Lopez, C; Richardson, FC; Rowland, PH; Tennant, BC; Tochkov, IA; Yeager, AE1
Miller, JP; Mintz, PD1
Kocic, I1
Boyer, N; Castelneau, C; Marcellin, P1

Reviews

7 review(s) available for arabinofuranosyluracil and Hepatitis B Virus Infection

ArticleYear
Drugs in development for hepatitis B.
    Drugs, 2005, Volume: 65, Issue:11

    Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Interferon alpha-2; Interferon-alpha; Nucleosides; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir

2005
New nucleoside analogues for chronic hepatitis B.
    Journal of hepatology, 1995, Volume: 22, Issue:1 Suppl

    Topics: 2-Aminopurine; Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; Drug Evaluation, Preclinical; Famciclovir; Hepatitis B; Humans; Lamivudine; Nucleosides; Zalcitabine

1995
New developments in antiviral therapy for chronic hepatitis B infection.
    Scandinavian journal of gastroenterology. Supplement, 1995, Volume: 212

    Topics: 2-Aminopurine; Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Famciclovir; Hepatitis B; Hepatitis, Chronic; Humans; Interferon-alpha; Lamivudine; Treatment Outcome; Zalcitabine

1995
Mechanisms for the anti-hepatitis B virus activity and mitochondrial toxicity of fialuridine (FIAU).
    Antiviral research, 1996, Volume: 29, Issue:2-3

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; DNA, Mitochondrial; Electron Transport Complex IV; Hepatitis B; Hepatitis B virus; Humans; Liver

1996
Mitochondrial injury. Lessons from the fialuridine trial.
    Drug safety, 1997, Volume: 17, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; DNA-Directed DNA Polymerase; Hepatitis B; Hepatitis B virus; Humans; Liver; Mitochondria; Oxidation-Reduction; Pyruvates; Risk Assessment; Structure-Activity Relationship

1997
Clevudine University of Georgia/Abbott/Bukwang/Triangle/Yale University.
    Current opinion in investigational drugs (London, England : 2000), 2000, Volume: 1, Issue:3

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Clinical Trials as Topic; Contraindications; Drugs, Investigational; Epstein-Barr Virus Infections; Hepatitis B; Humans; Structure-Activity Relationship

2000
[New management strategies for hepatitis B].
    Gastroenterologie clinique et biologique, 2002, Volume: 26, Issue:2

    Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; Emtricitabine; Guanine; Hepatitis B; Humans; Lamivudine; Organophosphonates

2002

Trials

4 trial(s) available for arabinofuranosyluracil and Hepatitis B Virus Infection

ArticleYear
Rapid quantitative determination of L-FMAU-TP from human peripheral-blood mononuclear cells of hepatitis B virus-infected patients treated with L-FMAU by ion-pairing, reverse-phase, liquid chromatography/electrospray tandem mass spectrometry.
    Therapeutic drug monitoring, 2006, Volume: 28, Issue:1

    Topics: Adult; Antiviral Agents; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Chromatography, High Pressure Liquid; Half-Life; Hepatitis B; Humans; Mass Spectrometry; Middle Aged; Reproducibility of Results

2006
Twenty-four-week clevudine therapy showed potent and sustained antiviral activity in HBeAg-positive chronic hepatitis B.
    Hepatology (Baltimore, Md.), 2007, Volume: 45, Issue:5

    Topics: Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Double-Blind Method; Female; Hepatitis B; Hepatitis B e Antigens; Hepatitis B, Chronic; Humans; Male; Middle Aged; Placebos

2007
Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.
    The New England journal of medicine, 1995, Oct-26, Volume: 333, Issue:17

    Topics: Acidosis, Lactic; Adult; Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; DNA, Mitochondrial; DNA, Viral; Drugs, Investigational; Female; Hepatitis B; Humans; Jaundice; Liver; Liver Failure; Liver Transplantation; Male; Middle Aged; Pancreatitis; Peripheral Nervous System Diseases

1995
Deaths in US fialuridine trial.
    Lancet (London, England), 1994, Jun-11, Volume: 343, Issue:8911

    Topics: Acidosis, Lactic; Acquired Immunodeficiency Syndrome; Animals; Antiviral Agents; Arabinofuranosyluracil; Cause of Death; Chronic Disease; Female; Hepatitis B; Humans; Male; Middle Aged; Survival Rate

1994

Other Studies

19 other study(ies) available for arabinofuranosyluracil and Hepatitis B Virus Infection

ArticleYear
Clevudine Induced Mitochondrial Myopathy.
    Journal of Korean medical science, 2017, Volume: 32, Issue:11

    Topics: Adult; Aged; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; Databases, Factual; Electromyography; Female; Hepatitis B; Humans; L-Lactate Dehydrogenase; Lower Extremity; Male; Middle Aged; Mitochondrial Myopathies; Muscle, Skeletal; Neck

2017
Polymyositis in patients taking antiviral clevudine therapy: a report of two cases.
    NeuroRehabilitation, 2010, Volume: 26, Issue:2

    Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Creatine Kinase; Female; Hepatitis B; Humans; Male; Middle Aged; Polymyositis

2010
Focus.
    Journal of hepatology, 2010, Volume: 53, Issue:2

    Topics: Albumins; Antiviral Agents; Arabinofuranosyluracil; Cholangitis, Sclerosing; Cholestasis; Dialysis Solutions; Gastrointestinal Neoplasms; Hepatitis B; Humans; Incidence; Muscular Diseases; Pruritus; Renal Dialysis; Risk Factors

2010
Clevudine-induced viral response, associated with continued reduction of HBsAg titer, was durable after the withdrawal of therapy.
    Journal of gastroenterology, 2011, Volume: 46, Issue:3

    Topics: Alanine Transaminase; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Follow-Up Studies; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Viral Load

2011
Rebound of hepatitis B virus replication in HepG2 cells after cessation of antiviral treatment.
    Journal of virology, 2002, Volume: 76, Issue:16

    Topics: Antiviral Agents; Arabinofuranosyluracil; Baculoviridae; Cell Line; DNA, Viral; Hepatitis B; Hepatitis B virus; Humans; Kinetics; Lamivudine; Recombination, Genetic; Virus Replication

2002
Effect of a combination of clevudine and emtricitabine with adenovirus-mediated delivery of gamma interferon in the woodchuck model of hepatitis B virus infection.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:7

    Topics: Adenoviridae; Animals; Antiviral Agents; Arabinofuranosyluracil; Deoxycytidine; DNA-Directed DNA Polymerase; Drug Combinations; Emtricitabine; Genetic Therapy; Hepatitis B; Hepatitis B Core Antigens; Hepatitis B Virus, Woodchuck; Interferon-gamma; Liver; Marmota; Microscopy, Confocal; Microscopy, Electron; Mitochondria, Liver; Proliferating Cell Nuclear Antigen; Recombinant Proteins; Reverse Transcriptase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Viremia; Virus Replication

2004
Mitochondrial toxicity--new adverse drug effects.
    The New England journal of medicine, 1995, Oct-26, Volume: 333, Issue:17

    Topics: Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; Clinical Trials as Topic; DNA, Mitochondrial; Hepatitis B; Humans; Liver Failure

1995
Effects of fialuridine on hepatitis B immune globulin pharmacokinetics following orthotopic liver transplant for chronic hepatitis B viral-induced cirrhosis.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; DNA, Viral; Female; Hepatitis B; Hepatitis B Core Antigens; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Immunoglobulins, Intravenous; Liver Cirrhosis; Liver Transplantation; Male

1995
Clinical course of four patients receiving the experimental antiviral agent fialuridine for the treatment of chronic hepatitis B infection.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Hepatitis B; Humans; Lactates; Liver Transplantation; Randomized Controlled Trials as Topic

1995
NIH panel report of 'no flaws' in FIAU trial at variance with FDA report, new probe planned.
    JAMA, 1994, Jul-06, Volume: 272, Issue:1

    Topics: Antiviral Agents; Arabinofuranosyluracil; Cause of Death; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Hepatitis B; Hepatitis, Chronic; Humans; Liver Diseases; National Institutes of Health (U.S.); Scientific Misconduct; United States; United States Food and Drug Administration

1994
Hepatitis study. Drug trial deaths deemed unavoidable.
    Science (New York, N.Y.), 1994, Jun-10, Volume: 264, Issue:5165

    Topics: Antiviral Agents; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Federal Government; Government Regulation; Hepatitis B; Humans; National Institutes of Health (U.S.); Pancreatic Diseases; Research Subjects; United States; United States Food and Drug Administration

1994
NIH, FDA seek lessons from hepatitis B drug trial deaths.
    Nature, 1993, Jul-22, Volume: 364, Issue:6435

    Topics: Antiviral Agents; Arabinofuranosyluracil; Hepatitis B; Humans; National Institutes of Health (U.S.); United States; United States Food and Drug Administration

1993
Severe toxicity of fialuridine (FIAU)
    The New England journal of medicine, 1996, Apr-25, Volume: 334, Issue:17

    Topics: Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; Hepatitis B; Humans; Interferons; Nucleosides

1996
Severe toxicity of fialuridine (FIAU)
    The New England journal of medicine, 1996, Apr-25, Volume: 334, Issue:17

    Topics: Antiviral Agents; Arabinofuranosyluracil; DNA Polymerase III; DNA, Mitochondrial; Drug Evaluation, Preclinical; Hepatitis B; Humans; In Vitro Techniques

1996
Severe toxicity of fialuridine (FIAU)
    The New England journal of medicine, 1996, Apr-25, Volume: 334, Issue:17

    Topics: Antiviral Agents; Arabinofuranosyluracil; Chronic Disease; Cytarabine; Drug Approval; Hepatitis B; Humans

1996
Depletion of mitochondrial DNA, destruction of mitochondria, and accumulation of lipid droplets result from fialuridine treatment in woodchucks (Marmota monax).
    Laboratory investigation; a journal of technical methods and pathology, 1997, Volume: 76, Issue:1

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; DNA Damage; DNA, Mitochondrial; Heart; Hepatitis B; Hepatitis B Virus, Woodchuck; Kidney; Lipids; Liver; Marmota; Mitochondria; Mitochondria, Muscle; Muscle, Skeletal; Myocardium

1997
Histopathologic changes associated with fialuridine hepatotoxicity.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 1997, Volume: 10, Issue:3

    Topics: Adult; Antiviral Agents; Arabinofuranosyluracil; Chemical and Drug Induced Liver Injury; Chronic Disease; Clinical Trials, Phase II as Topic; Female; Hepatitis B; Humans; Liver; Male; Middle Aged; Randomized Controlled Trials as Topic

1997
Antiviral activity and toxicity of fialuridine in the woodchuck model of hepatitis B virus infection.
    Hepatology (Baltimore, Md.), 1998, Volume: 28, Issue:1

    Topics: Animals; Anorexia; Antiviral Agents; Arabinofuranosyluracil; Carrier State; DNA, Viral; Hepatitis B; Hepatitis B Core Antigens; Hepatitis B virus; Liver; Marmota; Muscles; Sleep Stages; Time Factors; Virus Replication

1998
Falsely low calcium measurements after high volume plasma exchange in a patient with liver failure.
    Transfusion science, 1994, Volume: 15, Issue:3

    Topics: Acidosis, Lactic; Anticoagulants; Antiviral Agents; Arabinofuranosyluracil; Calcium; Citrates; Citric Acid; Hepatitis B; Hepatorenal Syndrome; Humans; Liver Failure; Liver Transplantation; Male; Middle Aged; Plasma Exchange; Predictive Value of Tests; Spectrophotometry, Atomic

1994