arabinofuranosylcytosine triphosphate and Acute Disease

arabinofuranosylcytosine triphosphate has been researched along with Acute Disease in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19909 (39.13)18.7374
1990's12 (52.17)18.2507
2000's2 (8.70)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bowman, WP; Danks, MK; Look, AT; Ochs, J; Rivera, G; Sinkule, JA1
Brach, MA; Herrmann, F; Mertelsmann, RH1
Buck, SA; Gurney, JG; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW1
Büchner, T; Hiddemann, W; Kern, W; Schleyer, E; Unterhalt, M1
Cao, DC; Higashigawa, M; Hori, H; Ido, M; Kawasaki, H; Sakurai, M; Shindou, K1
Alton, P; Elgie, AW; Noordhuis, P; Peters, GJ; Sargent, JM; Taylor, CG; Williamson, CJ1
Du, M; Estey, E; Gandhi, V; Keating, MJ; Plunkett, W1
Rowe, JM1
Fukushima, T; Goto, N; Imamura, S; Iwasaki, H; Kawai, Y; Kishi, S; Masada, M; Tsutani, H; Ueda, T; Urasaki, Y; Yamauchi, T; Yoshida, A1
Büchner, T; Hiddemann, W; Kewer, U; Reuter, C; Rolf, C; Schleyer, E; Uhrmeister, C; Unterhalt, M; Wörmann, B; Zühlsdorf, M1
Büchner, T; Busemann, C; Hiddemann, W; Kiehl, M; Schleyer, E; Wörmann, B; Zühlsdorf, M1
Tanaka, M1
Busch, FW; Ehninger, G; Hiddemann, W; Jaschonek, K; Proksch, B; Schleyer, E; Schmidt, H; Schuler, U; Wanner, T1
Arlin, Z; Bhalla, K; Grant, S; Holladay, C; Ibrado, AM; Jasiok, M1
Jamieson, GP; Snook, MB; Wiley, JS1
Iacoboni, S; Keating, MJ; Plunkett, W1
Keating, MJ; Nowak, B; Plunkett, W1
Preisler, HD; Riva, C; Rustum, YM1
Gahrton, G; Liliemark, JO; Paul, CY; Peterson, CO1
Akman, SA; Joneckis, CC; Ross, DD; Schiffer, CA; Thompson, BW2
Azarnia, N; Preisler, HD; Priore, R; Rustum, YM1
Preisler, HD; Priore, RL; Rustum, Y1

Reviews

2 review(s) available for arabinofuranosylcytosine triphosphate and Acute Disease

ArticleYear
Modulation of cytotoxicity and differentiation-inducing potential of arabinofuranosylcytosine in myeloid leukemia cells by hematopoietic cytokines.
    Cancer investigation, 1993, Volume: 11, Issue:2

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Cell Differentiation; Cell Division; Colony-Stimulating Factors; Cytarabine; Drug Combinations; Growth Inhibitors; Hematopoietic Cell Growth Factors; Humans; Interleukin-6; Leukemia Inhibitory Factor; Leukemia, Myeloid; Lymphokines; Tumor Cells, Cultured; Tumor Stem Cell Assay

1993
Concurrent use of growth factors and chemotherapy in acute leukemia.
    Current opinion in hematology, 2000, Volume: 7, Issue:3

    Topics: Acute Disease; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Clinical Trials as Topic; Colony-Stimulating Factors; Growth Substances; Humans; Leukemia

2000

Trials

1 trial(s) available for arabinofuranosylcytosine triphosphate and Acute Disease

ArticleYear
Effect of amsacrine on ara-CTP cellular pharmacology in human leukemia cells during high-dose cytarabine therapy.
    Cancer treatment reports, 1987, Volume: 71, Issue:5

    Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cells, Cultured; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged

1987

Other Studies

20 other study(ies) available for arabinofuranosylcytosine triphosphate and Acute Disease

ArticleYear
Continuous infusion high-dose cytosine arabinoside in refractory childhood leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:10

    Topics: Acute Disease; Adolescent; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Child; Child, Preschool; Cytarabine; Deoxycytosine Nucleotides; Drug Administration Schedule; Humans; Infusions, Parenteral; Kinetics; Leukemia; Leukemia, Lymphoid

1984
Enhanced metabolism of 1-beta-D-arabinofuranosylcytosine in Down syndrome cells: a contributing factor to the superior event free survival of Down syndrome children with acute myeloid leukemia.
    Blood, 1996, Apr-15, Volume: 87, Issue:8

    Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cell Line, Transformed; Cells, Cultured; Child; Child, Preschool; Chromosomes, Human, Pair 21; Cystathionine beta-Synthase; Cytarabine; Deoxycytosine Nucleotides; Disease-Free Survival; Down Syndrome; Female; Herpesvirus 4, Human; Homocysteine; Humans; Infant; Infant, Newborn; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Male; Methotrexate; Myelodysplastic Syndromes; Neoplastic Stem Cells; Remission, Spontaneous; Survival Rate

1996
Optimizing therapy for acute myeloid leukemia based on differences in intracellular metabolism of cytosine arabinoside between leukemic blasts and normal mononuclear blood cells.
    Therapeutic drug monitoring, 1996, Volume: 18, Issue:4

    Topics: Acute Disease; Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Female; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Male

1996
Deoxycytidine kinase mRNA levels in leukemia cells with competitive polymerase chain reaction assay.
    Leukemia research, 1996, Volume: 20, Issue:8

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Deoxycytidine Kinase; Humans; Leukemia; Leukemia, Myeloid; Nucleic Acid Synthesis Inhibitors; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger; Transcription, Genetic

1996
Modulation of resistance to ara-C by bryostatin in fresh blast cells from patients with AML.
    Leukemia research, 1998, Volume: 22, Issue:4

    Topics: Acute Disease; Antineoplastic Agents; Arabinofuranosylcytosine Triphosphate; Bryostatins; Cell Death; Cytarabine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Lactones; Leukemia, Myeloid; Leukocytes, Mononuclear; Macrolides; Tetrazolium Salts; Thiazoles

1998
Minimum dose of fludarabine for the maximal modulation of 1-beta-D-arabinofuranosylcytosine triphosphate in human leukemia blasts during therapy.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:9

    Topics: Acute Disease; Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Time Factors; Vidarabine

1997
Close correlation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate, an intracellular active metabolite, to the therapeutic efficacy of N(4)-behenoyl-1-beta-D-arabinofuranosylcytosine therapy for acute myelogenous leukemia.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:9

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Area Under Curve; Biotransformation; Cytarabine; Female; Humans; Infusions, Intravenous; Intracellular Fluid; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Prodrugs; Remission Induction; Sensitivity and Specificity; Treatment Outcome

2001
Differences in the intracellular pharmacokinetics of cytosine arabinoside (AraC) between circulating leukemic blasts and normal mononuclear blood cells.
    Leukemia, 1992, Volume: 6, Issue:12

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine

1992
Granulocyte-macrophage colony-stimulating factor and interleukin-3 enhance the incorporation of cytosine arabinoside into the DNA of leukemic blasts and the cytotoxic effect on clonogenic cells from patients with acute myeloid leukemia.
    Seminars in oncology, 1992, Volume: 19, Issue:2 Suppl 4

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Blast Crisis; Cytarabine; DNA, Neoplasm; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; S Phase; Tumor Stem Cell Assay

1992
Enhancement of the cytotoxicity of cytosine arabinoside by interleukin-3.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:2

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Blast Crisis; Cytarabine; Drug Synergism; Feasibility Studies; Humans; Interleukin-1; Interleukin-3; Leukemia, Myeloid; Tumor Stem Cell Assay

1992
Intracellular cytosine arabinoside accumulation and cytosine arabinoside triphosphate formation in leukemic blast cells is inhibited by etoposide and teniposide.
    Leukemia, 1992, Volume: 6, Issue:6

    Topics: Acute Disease; Adult; Aged; Amsacrine; Arabinofuranosylcytosine Triphosphate; Cytarabine; Drug Interactions; Etoposide; Humans; Leukemia; Middle Aged; Neoplastic Stem Cells; Phosphorylation; Teniposide; Tumor Cells, Cultured

1992
Treatment with interleukin-3 plus granulocyte-macrophage colony-stimulating factors improves the selectivity of Ara-C in vitro against acute myeloid leukemia blasts.
    Blood, 1991, Nov-15, Volume: 78, Issue:10

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Blast Crisis; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Kinetics; Leukemia, Myeloid; Monocytes; Recombinant Proteins; Reference Values; Stem Cells; Tumor Cells, Cultured

1991
Saturation of intracellular cytosine arabinoside triphosphate accumulation in human leukemic blast cells.
    Leukemia research, 1990, Volume: 14, Issue:5

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Binding Sites; Biological Transport; Cell Membrane; Cytarabine; Deoxycytidine Kinase; Extracellular Space; Humans; Leukemia; Lymphocytes; Nucleosides; Phosphorylation; Thioinosine; Tumor Cells, Cultured

1990
Cellular pharmacology and optimal therapeutic concentrations of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in leukemic blasts during treatment of refractory leukemia with high-dose 1-beta-D-arabinofuranosylcytosine.
    Scandinavian journal of haematology. Supplementum, 1986, Volume: 44

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Biotransformation; Chromatography, High Pressure Liquid; Cytarabine; Humans; Kinetics; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute

1986
Pharmacokinetic parameters of 1-beta-D-arabinofuranosylcytosine (ara-C) and their relationship to intracellular metabolism of ara-C, toxicity, and response of patients with acute nonlymphocytic leukemia treated with conventional and high-dose ara-C.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Acute Disease; Animals; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Drug Administration Schedule; Humans; Leukemia; Leukemia L1210; Metabolic Clearance Rate; Mice; Uridine Kinase

1987
ara-C in plasma and ara-CTP in leukemic cells after subcutaneous injection and continuous intravenous infusion of ara-C in patients with acute nonlymphoblastic leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Acute Disease; Adult; Aged; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Female; Humans; Infusions, Intravenous; Injections, Subcutaneous; Leukemia; Male; Metabolic Clearance Rate; Middle Aged

1987
Studies of ara-C metabolism in acute leukemia.
    Seminars in oncology, 1987, Volume: 14, Issue:2 Suppl 1

    Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Bromodeoxyuridine; Cell Line; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leukemia; Thymidine

1987
Metabolism of ara-C by blast cells from patients with ANLL.
    Blood, 1986, Volume: 68, Issue:1

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Cytarabine; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Leukemia; Male; Middle Aged

1986
Abrogation of the prognostic significance of low leukemic cell retention of cytosine arabinoside triphosphate by intensification of therapy and by alteration in the dose and schedule of administration of cytosine arabinoside.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:1

    Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Bone Marrow; Cytarabine; Doxorubicin; Humans; Leukemia; Middle Aged; Neoplasm Proteins; Phosphorylation; Prognosis

1987
Relationship between leukemic cell retention of cytosine arabinoside triphosphate and the duration of remission in patients with acute non-lymphocytic leukemia.
    European journal of cancer & clinical oncology, 1985, Volume: 21, Issue:1

    Topics: Acute Disease; Adult; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cytarabine; Female; Humans; Leukemia; Male; Middle Aged; Phosphorylation; Time Factors

1985