apyrase has been researched along with Anti-Neutrophil-Cytoplasmic-Antibody-Associated-Vasculitis* in 1 studies
1 other study(ies) available for apyrase and Anti-Neutrophil-Cytoplasmic-Antibody-Associated-Vasculitis
| Article | Year |
|---|---|
Changes in CD73, CD39 and CD26 expression on T-lymphocytes of ANCA-associated vasculitis patients suggest impairment in adenosine generation and turn-over.
Extracellular adenosine, generated via the concerted action of CD39 and CD73, contributes to T-cell differentiation and function. Adenosine concentrations are furthermore influenced by adenosine deaminase binding protein CD26. Because aberrant T-cell phenotypes had been reported in anti-neutrophil cytoplasmic auto-antibody (ANCA)-associated vasculitis (AAV) patients, an impaired expression of these molecules on T-cells of AAV patients was hypothesized in the present study. While in AAV patients (n = 29) CD26 was increased on CD4 Topics: 5'-Nucleotidase; Adenosine; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Apyrase; C-Reactive Protein; Dipeptidyl Peptidase 4; Female; Glomerular Filtration Rate; GPI-Linked Proteins; Humans; Male; Middle Aged; T-Lymphocytes; Young Adult | 2017 |