aptiganel has been researched along with Cerebrovascular Disorders in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grosset, DG; Lees, KR; Muir, KW | 1 |
| Cotter, RE; Davis, MA; Fisher, M; Knapp, AG; Li, L; McBurney, RN; Minematsu, K; Sotak, CH | 1 |
| Cohen, RA; Fisher, M; Hasegawa, Y | 1 |
| McBurney, RN | 1 |
| Lees, KR | 1 |
2 review(s) available for aptiganel and Cerebrovascular Disorders
| Article | Year |
|---|---|
Development of the NMDA ion-channel blocker, aptiganel hydrochloride, as a neuroprotective agent for acute CNS injury.
Topics: Acute Disease; Brain Injuries; Cerebrovascular Disorders; Clinical Trials as Topic; Drugs, Investigational; Glasgow Coma Scale; Guanidines; Humans; N-Methylaspartate; Neuroprotective Agents; Reference Values; Spinal Cord Injuries | 1997 |
Cerestat and other NMDA antagonists in ischemic stroke.
Topics: Brain Ischemia; Cerebrovascular Disorders; Excitatory Amino Acid Antagonists; Guanidines; Humans; Receptors, N-Methyl-D-Aspartate | 1997 |
1 trial(s) available for aptiganel and Cerebrovascular Disorders
| Article | Year |
|---|---|
Clinical pharmacology of CNS 1102 in man.
Topics: Brain Injuries; Cardiovascular System; Cerebrovascular Circulation; Cerebrovascular Disorders; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Excitatory Amino Acid Antagonists; Guanidines; Humans; Male; Neuroprotective Agents | 1995 |
2 other study(ies) available for aptiganel and Cerebrovascular Disorders
| Article | Year |
|---|---|
Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI.
Topics: Animals; Cerebral Infarction; Cerebrovascular Disorders; Disease Models, Animal; Guanidines; Ischemic Attack, Transient; Kinetics; Magnetic Resonance Imaging; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Staining and Labeling; Tetrazolium Salts; Time Factors | 1993 |
Effects of a novel NMDA receptor antagonist on experimental stroke quantitatively assessed by spectral EEG and infarct volume.
Topics: Animals; Cerebral Infarction; Cerebrovascular Disorders; Electroencephalography; Functional Laterality; Guanidines; Ischemic Attack, Transient; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Time Factors | 1994 |